We propose a conceptual device for a multiplexed biosensor in a photonic crystal chip based on the Su-Schrieffer-Heeger mechanism.Remarkably,the proposed biosensor can identify three distinct disease markers through a...We propose a conceptual device for a multiplexed biosensor in a photonic crystal chip based on the Su-Schrieffer-Heeger mechanism.Remarkably,the proposed biosensor can identify three distinct disease markers through a single-shot photon transmission measurement,thanks to the couplings among the three Su-Schrieffer-Heeger boundary modes in the photonic crystal.Our biosensor design is more robust against defects and disorders that are inevitable in real-life device applications than previous designs.Such robustness is invaluable for achieving efficient,reliable,and integrated biosensing based on nanophotonic systems.We further demonstrate that various combinations of disease markers can be recognized via the photon transmission spectrum,thus unveiling a promising route toward high-performance,advanced biosensing for future biomedical technology.展开更多
基金supported by the National Key R&D Program of China(No.2022YFA1404400)support from the National Natural Science Foundation of China(Grant Nos.12125504 and12074281)the Priority Academic Program Development(PAPD)of Jiangsu Higher Education Institutions.
文摘We propose a conceptual device for a multiplexed biosensor in a photonic crystal chip based on the Su-Schrieffer-Heeger mechanism.Remarkably,the proposed biosensor can identify three distinct disease markers through a single-shot photon transmission measurement,thanks to the couplings among the three Su-Schrieffer-Heeger boundary modes in the photonic crystal.Our biosensor design is more robust against defects and disorders that are inevitable in real-life device applications than previous designs.Such robustness is invaluable for achieving efficient,reliable,and integrated biosensing based on nanophotonic systems.We further demonstrate that various combinations of disease markers can be recognized via the photon transmission spectrum,thus unveiling a promising route toward high-performance,advanced biosensing for future biomedical technology.
