Asthma is the most common allergic disorder and represents a significant global public health problem.Strong evidence suggests a link between ascariasis and asthma.This study aims primarily to determine the prevalence...Asthma is the most common allergic disorder and represents a significant global public health problem.Strong evidence suggests a link between ascariasis and asthma.This study aims primarily to determine the prevalence of Ascaris lumbricoides infection among various risk factors,to assess blood parameters,levels of immunoglobulin E(IgE)and interleukin-4(IL-4),and to explore the relationship between ascariasis and asthma in affected individuals.The secondary objective is to examine a fractal-fractional mathematical model that describes the four stages of the life cycle of Ascaris infection,specifically within the framework of the Caputo-Fabrizio derivative.A case-control study was conducted that involved 270 individuals with asthma and 130 healthy controls,all of whom attended general hospitals in Duhok City,Iraq.Pulmonary function tests were performed using a micromedical spirometer.The presence of Ascaris lumbricoides antibodies-Immunoglobulin M(IgM),Immunoglobulin G(IgG),and Immunoglobulin E(IgE)-was detected using ELISA.Blood parameters were analyzed using a Coulter counter.The overall infection rate was(42.5%),with the highest rates observed among asthmatic men(70.0%)and rural residents(51.4%).Higher infection rates were also recorded among low-income individuals(64.3%)and those with frequent contact with the soil(58.6%).In particular,infected individuals exhibited a significant decrease in red blood cell count and hemoglobin concentration,while a marked increase in white blood cell count was recorded.In addition,levels of Immunoglobulin E(IgE)and interleukin-4 were significantly higher in the infected group compared to the controls.Effective disease awareness strategies that incorporate health education and preventive measures are needed.Exposure to Ascaris has been associated with reduced lung function and an increased risk of asthma.More research is required to elucidate the precise mechanisms that link Ascaris infection with asthma.Furthermore,the existence and uniqueness of solutions for the proposed model are investigated using the Krasnosel’skii and Banach fixed-point theorems.The Ulam-Hyers and Ulam-Hyers-Rassias stability types are explained within the framework of nonlinear analysis inŁp-space.Finally,an application is presented,including tabulated results and figures generated using MATLAB to illustrate the validity of the theoretical findings.展开更多
在Banach空间中研究一类具有Caputo-Fabrizio分数阶导数且在非局部条件下的脉冲分数阶微分方程解的存在性。利用Schaefer不动点定理,压缩映射原理,Arzela-Ascoli定理,得到了该脉冲分数阶问题至少一个解和唯一解,并用一个例子验证其中一...在Banach空间中研究一类具有Caputo-Fabrizio分数阶导数且在非局部条件下的脉冲分数阶微分方程解的存在性。利用Schaefer不动点定理,压缩映射原理,Arzela-Ascoli定理,得到了该脉冲分数阶问题至少一个解和唯一解,并用一个例子验证其中一个结论。The existence of a class of impulsive fractional differential equations with Caputo-Fabrizio fractional derivatives under non-local conditions is studied in Banach space. Based on Schaefer’s fixed point theorem, compression mapping principle and Arzela-Ascoli theorem, at least one solution and the only solution of the pulse fractional order problem are obtained, and one of the conclusions is verified by an example.展开更多
Asymptotic stability of linear and interval linear fractional-order neutral delay differential systems described by the Caputo-Fabrizio (CF) fractional derivatives is investigated. Using Laplace transform, a novel cha...Asymptotic stability of linear and interval linear fractional-order neutral delay differential systems described by the Caputo-Fabrizio (CF) fractional derivatives is investigated. Using Laplace transform, a novel characteristic equation is derived. Stability criteria are established based on an algebraic approach and norm-based criteria are also presented. It is shown that asymptotic stability is ensured for linear fractional-order neutral delay differential systems provided that the underlying stability criterion holds for any delay parameter. In addition, sufficient conditions are derived to ensure the asymptotic stability of interval linear fractional order neutral delay differential systems. Examples are provided to illustrate the effectiveness and applicability of the theoretical results.展开更多
In this paper, we consider numerical solutions of fractional ordinary diferential equations with the Caputo-Fabrizio derivative, and construct and analyze a high-order time-stepping scheme for this equation. The propo...In this paper, we consider numerical solutions of fractional ordinary diferential equations with the Caputo-Fabrizio derivative, and construct and analyze a high-order time-stepping scheme for this equation. The proposed method makes use of quadratic interpolation function in sub-intervals, which allows to produce fourth-order convergence. A rigorous stability and convergence analysis of the proposed scheme is given. A series of numerical examples are presented to validate the theoretical claims. Traditionally a scheme having fourth-order convergence could only be obtained by using block-by-block technique. The advantage of our scheme is that the solution can be obtained step by step, which is cheaper than a block-by-block-based approach.展开更多
This paper studies the time-fractional Korteweg-de Vries (KdV) equations with Caputo-Fabrizio fractional derivatives. The scheme is presented by using a finite difference method in temporal variable and a local discon...This paper studies the time-fractional Korteweg-de Vries (KdV) equations with Caputo-Fabrizio fractional derivatives. The scheme is presented by using a finite difference method in temporal variable and a local discontinuous Galerkin method (LDG) in space. Stability and convergence are demonstrated by a specific choice of numerical fluxes. Finally, the efficiency and accuracy of the scheme are verified by numerical experiments.展开更多
This study focuses on the dynamics of drug concentration in the blood.In general,the concentration level of a drug in the blood is evaluated by themean of an ordinary and first-order differential equation.More precise...This study focuses on the dynamics of drug concentration in the blood.In general,the concentration level of a drug in the blood is evaluated by themean of an ordinary and first-order differential equation.More precisely,it is solved through an initial value problem.We proposed a newmodeling technique for studying drug concentration in blood dynamics.This technique is based on two fractional derivatives,namely,Caputo and Caputo-Fabrizio derivatives.We first provided comprehensive and detailed proof of the existence of at least one solution to the problem;we later proved the uniqueness of the existing solution.The proof was written using the Caputo-Fabrizio fractional derivative and some fixed-point techniques.Stability via theUlam-Hyers(UH)technique was also investigated.The application of the proposedmodel on two real data sets revealed that the Caputo derivative wasmore suitable in this study.Indeed,for the first data set,the model based on the Caputo derivative yielded a Mean Squared Error(MSE)of 0.03095 with a corresponding best value of fractional order of derivative of 1.00360.Caputo-Fabrizio-basedderivative appeared to be the second-best method for the problem,with an MSE of 0.04324 for a corresponding best fractional derivative order of 0.43532.For the second experiment,Caputo derivative-based model still performed the best as it yielded an MSE of 0.04066,whereas the classical and the Caputo-Fabrizio methods were tied with the same MSE of 0.07299.Another interesting finding was that the MSE yielded by the Caputo-Fabrizio fractional derivative coincided with the MSE obtained from the classical approach.展开更多
Diabetes is a burning issue in the whole world.It is the imbalance between body glucose and insulin.The study of this imbalance is very much needed from a research point of view.For this reason,Bergman gave an importa...Diabetes is a burning issue in the whole world.It is the imbalance between body glucose and insulin.The study of this imbalance is very much needed from a research point of view.For this reason,Bergman gave an important model named-Bergman minimalmodel.In the present work,using Caputo-Fabrizio(CF)fractional derivative,we generalize Bergman’s minimal blood glucose-insulin model.Further,we modify the old model by including one more component known as diet D(t),which is also essential for the blood glucose model.We solve the modified modelwith the help of Sumudu transformand fixed-point iteration procedures.Also,using the fixed point theorem,we examine the existence and uniqueness of the results along with their numerical and graphical representation.Furthermore,the comparison between the values of parameters obtained by calculating different values of t with experimental data is also studied.Finally,we draw the graphs of G(t),X(t),I(t),andD(t)for different values ofτ.It is also clear from the obtained results and their graphical representation that the obtained results of modified Bergman’s minimal model are better than Bergman’s model.展开更多
The aim of this paper is to investigate the dynamic behaviors of fractional-order logistic model with Allee effects in Caputo-Fabrizio sense.First of all,we apply the two-step Adams-Bashforth scheme to discretize the ...The aim of this paper is to investigate the dynamic behaviors of fractional-order logistic model with Allee effects in Caputo-Fabrizio sense.First of all,we apply the two-step Adams-Bashforth scheme to discretize the fractional-order logistic differential equation and obtain the two-dimensional discrete system.The parametric conditions for local asymptotic stability of equilibrium points are obtained by Schur-Chon criterion.Moreover,we discuss the existence and direction for Neimark-Sacker bifurcations with the help of center manifold theorem and bifurcation theory.Numerical simulations are provided to illustrate theoretical discussion.It is observed that Allee effect plays an important role in stability analysis.Strong Allee effect in population enhances the stability of the coexisting steady state.In additional,the effect of fractional-order derivative on dynamic behavior of the system is also investigated.展开更多
This paper focuses on applying the barycentric Lagrange interpolation collocation method(BLICM)for solving 2D time-fractional diffusion-wave equation(TFDWE).In order to obtain the discrete format of the equation,we co...This paper focuses on applying the barycentric Lagrange interpolation collocation method(BLICM)for solving 2D time-fractional diffusion-wave equation(TFDWE).In order to obtain the discrete format of the equation,we construct the multivariate barycentric Lagrange interpolation approximation function and process the integral terms by using the Gauss-Legendre quadrature formula.We provide a detailed error analysis of the discrete format on the second kind of Chebyshev nodes.The efficacy of the proposed method is substantiated by some numerical experiments.The results of these experiments demonstrate that our method can obtain high-precision numerical solutions for fractional partial differential equations.Additionally,the method's capability to achieve high precision with a reduced number of nodes is confirmed.展开更多
This study introduces a novel mathematical model to describe the progression of cholera by integrating fractional derivatives with both singular and non-singular kernels alongside stochastic differential equations ove...This study introduces a novel mathematical model to describe the progression of cholera by integrating fractional derivatives with both singular and non-singular kernels alongside stochastic differential equations over four distinct time intervals.The model incorporates three key fractional derivatives:the Caputo-Fabrizio fractional derivative with a non-singular kernel,the Caputo proportional constant fractional derivative with a singular kernel,and the Atangana-Baleanu fractional derivative with a non-singular kernel.We analyze the stability of the core model and apply various numerical methods to approximate the proposed crossover model.To achieve this,the approximation of Caputo proportional constant fractional derivative with Grünwald-Letnikov nonstandard finite difference method is used for the deterministic model with a singular kernel,while the Toufik-Atangana method is employed for models involving a non-singular Mittag-Leffler kernel.Additionally,the integral Caputo-Fabrizio approximation and a two-step Lagrange polynomial are utilized to approximate the model with a non-singular exponential decay kernel.For the stochastic component,the Milstein method is implemented to approximate the stochastic differential equations.The stability and effectiveness of the proposed model and methodologies are validated through numerical simulations and comparisons with real-world cholera data from Yemen.The results confirm the reliability and practical applicability of the model,providing strong theoretical and empirical support for the approach.展开更多
In this paper,we study two fractional models in the Caputo–Fabrizio sense and Atangana–Baleanu sense,in which the effects of malaria infection on mosquito biting behavior and attractiveness of humans are considered....In this paper,we study two fractional models in the Caputo–Fabrizio sense and Atangana–Baleanu sense,in which the effects of malaria infection on mosquito biting behavior and attractiveness of humans are considered.Using Lyapunov theory,we prove the global asymptotic stability of the unique endemic equilibrium of the integer-order model,and the fractional models,whenever the basic reproduction number R0 is greater than one.By using fixed point theory,we prove existence,and conditions of the uniqueness of solutions,as well as the stability and convergence of numerical schemes.Numerical simulations for both models,using fractional Euler method and Adams–Bashforth method,respectively,are provided to confirm the effectiveness of used approximation methods for different values of the fractional-orderγ.展开更多
文摘Asthma is the most common allergic disorder and represents a significant global public health problem.Strong evidence suggests a link between ascariasis and asthma.This study aims primarily to determine the prevalence of Ascaris lumbricoides infection among various risk factors,to assess blood parameters,levels of immunoglobulin E(IgE)and interleukin-4(IL-4),and to explore the relationship between ascariasis and asthma in affected individuals.The secondary objective is to examine a fractal-fractional mathematical model that describes the four stages of the life cycle of Ascaris infection,specifically within the framework of the Caputo-Fabrizio derivative.A case-control study was conducted that involved 270 individuals with asthma and 130 healthy controls,all of whom attended general hospitals in Duhok City,Iraq.Pulmonary function tests were performed using a micromedical spirometer.The presence of Ascaris lumbricoides antibodies-Immunoglobulin M(IgM),Immunoglobulin G(IgG),and Immunoglobulin E(IgE)-was detected using ELISA.Blood parameters were analyzed using a Coulter counter.The overall infection rate was(42.5%),with the highest rates observed among asthmatic men(70.0%)and rural residents(51.4%).Higher infection rates were also recorded among low-income individuals(64.3%)and those with frequent contact with the soil(58.6%).In particular,infected individuals exhibited a significant decrease in red blood cell count and hemoglobin concentration,while a marked increase in white blood cell count was recorded.In addition,levels of Immunoglobulin E(IgE)and interleukin-4 were significantly higher in the infected group compared to the controls.Effective disease awareness strategies that incorporate health education and preventive measures are needed.Exposure to Ascaris has been associated with reduced lung function and an increased risk of asthma.More research is required to elucidate the precise mechanisms that link Ascaris infection with asthma.Furthermore,the existence and uniqueness of solutions for the proposed model are investigated using the Krasnosel’skii and Banach fixed-point theorems.The Ulam-Hyers and Ulam-Hyers-Rassias stability types are explained within the framework of nonlinear analysis inŁp-space.Finally,an application is presented,including tabulated results and figures generated using MATLAB to illustrate the validity of the theoretical findings.
文摘在Banach空间中研究一类具有Caputo-Fabrizio分数阶导数且在非局部条件下的脉冲分数阶微分方程解的存在性。利用Schaefer不动点定理,压缩映射原理,Arzela-Ascoli定理,得到了该脉冲分数阶问题至少一个解和唯一解,并用一个例子验证其中一个结论。The existence of a class of impulsive fractional differential equations with Caputo-Fabrizio fractional derivatives under non-local conditions is studied in Banach space. Based on Schaefer’s fixed point theorem, compression mapping principle and Arzela-Ascoli theorem, at least one solution and the only solution of the pulse fractional order problem are obtained, and one of the conclusions is verified by an example.
文摘Asymptotic stability of linear and interval linear fractional-order neutral delay differential systems described by the Caputo-Fabrizio (CF) fractional derivatives is investigated. Using Laplace transform, a novel characteristic equation is derived. Stability criteria are established based on an algebraic approach and norm-based criteria are also presented. It is shown that asymptotic stability is ensured for linear fractional-order neutral delay differential systems provided that the underlying stability criterion holds for any delay parameter. In addition, sufficient conditions are derived to ensure the asymptotic stability of interval linear fractional order neutral delay differential systems. Examples are provided to illustrate the effectiveness and applicability of the theoretical results.
基金This research was supported by the National Natural Science Foundation of China(Grant numbers 11501140,51661135011,11421110001,and 91630204)the Foundation of Guizhou Science and Technology Department(No.[2017]1086)The first author would like to acknowledge the financial support by the China Scholarship Council(201708525037).
文摘In this paper, we consider numerical solutions of fractional ordinary diferential equations with the Caputo-Fabrizio derivative, and construct and analyze a high-order time-stepping scheme for this equation. The proposed method makes use of quadratic interpolation function in sub-intervals, which allows to produce fourth-order convergence. A rigorous stability and convergence analysis of the proposed scheme is given. A series of numerical examples are presented to validate the theoretical claims. Traditionally a scheme having fourth-order convergence could only be obtained by using block-by-block technique. The advantage of our scheme is that the solution can be obtained step by step, which is cheaper than a block-by-block-based approach.
文摘This paper studies the time-fractional Korteweg-de Vries (KdV) equations with Caputo-Fabrizio fractional derivatives. The scheme is presented by using a finite difference method in temporal variable and a local discontinuous Galerkin method (LDG) in space. Stability and convergence are demonstrated by a specific choice of numerical fluxes. Finally, the efficiency and accuracy of the scheme are verified by numerical experiments.
基金supported through the Annual Funding Track by the Deanship of Scientific Research,Vice Presidency for Graduate Studies and Scientific Research,King Faisal University,Saudi Arabia[Project No.AN000273],granted after a successful application by M.A.
文摘This study focuses on the dynamics of drug concentration in the blood.In general,the concentration level of a drug in the blood is evaluated by themean of an ordinary and first-order differential equation.More precisely,it is solved through an initial value problem.We proposed a newmodeling technique for studying drug concentration in blood dynamics.This technique is based on two fractional derivatives,namely,Caputo and Caputo-Fabrizio derivatives.We first provided comprehensive and detailed proof of the existence of at least one solution to the problem;we later proved the uniqueness of the existing solution.The proof was written using the Caputo-Fabrizio fractional derivative and some fixed-point techniques.Stability via theUlam-Hyers(UH)technique was also investigated.The application of the proposedmodel on two real data sets revealed that the Caputo derivative wasmore suitable in this study.Indeed,for the first data set,the model based on the Caputo derivative yielded a Mean Squared Error(MSE)of 0.03095 with a corresponding best value of fractional order of derivative of 1.00360.Caputo-Fabrizio-basedderivative appeared to be the second-best method for the problem,with an MSE of 0.04324 for a corresponding best fractional derivative order of 0.43532.For the second experiment,Caputo derivative-based model still performed the best as it yielded an MSE of 0.04066,whereas the classical and the Caputo-Fabrizio methods were tied with the same MSE of 0.07299.Another interesting finding was that the MSE yielded by the Caputo-Fabrizio fractional derivative coincided with the MSE obtained from the classical approach.
文摘Diabetes is a burning issue in the whole world.It is the imbalance between body glucose and insulin.The study of this imbalance is very much needed from a research point of view.For this reason,Bergman gave an important model named-Bergman minimalmodel.In the present work,using Caputo-Fabrizio(CF)fractional derivative,we generalize Bergman’s minimal blood glucose-insulin model.Further,we modify the old model by including one more component known as diet D(t),which is also essential for the blood glucose model.We solve the modified modelwith the help of Sumudu transformand fixed-point iteration procedures.Also,using the fixed point theorem,we examine the existence and uniqueness of the results along with their numerical and graphical representation.Furthermore,the comparison between the values of parameters obtained by calculating different values of t with experimental data is also studied.Finally,we draw the graphs of G(t),X(t),I(t),andD(t)for different values ofτ.It is also clear from the obtained results and their graphical representation that the obtained results of modified Bergman’s minimal model are better than Bergman’s model.
文摘The aim of this paper is to investigate the dynamic behaviors of fractional-order logistic model with Allee effects in Caputo-Fabrizio sense.First of all,we apply the two-step Adams-Bashforth scheme to discretize the fractional-order logistic differential equation and obtain the two-dimensional discrete system.The parametric conditions for local asymptotic stability of equilibrium points are obtained by Schur-Chon criterion.Moreover,we discuss the existence and direction for Neimark-Sacker bifurcations with the help of center manifold theorem and bifurcation theory.Numerical simulations are provided to illustrate theoretical discussion.It is observed that Allee effect plays an important role in stability analysis.Strong Allee effect in population enhances the stability of the coexisting steady state.In additional,the effect of fractional-order derivative on dynamic behavior of the system is also investigated.
基金Supported by the Scientific Research Foundation for Talents Introduced of Guizhou University of Finance and Economics(Grant No.2023YJ16)the Institute of Complexity Science,Henan University of Technology(Grant No.CSKFJJ-2025-33)the International Science and Technology Cooperation Project of Henan Province(Grant No.252102520007).
文摘This paper focuses on applying the barycentric Lagrange interpolation collocation method(BLICM)for solving 2D time-fractional diffusion-wave equation(TFDWE).In order to obtain the discrete format of the equation,we construct the multivariate barycentric Lagrange interpolation approximation function and process the integral terms by using the Gauss-Legendre quadrature formula.We provide a detailed error analysis of the discrete format on the second kind of Chebyshev nodes.The efficacy of the proposed method is substantiated by some numerical experiments.The results of these experiments demonstrate that our method can obtain high-precision numerical solutions for fractional partial differential equations.Additionally,the method's capability to achieve high precision with a reduced number of nodes is confirmed.
文摘This study introduces a novel mathematical model to describe the progression of cholera by integrating fractional derivatives with both singular and non-singular kernels alongside stochastic differential equations over four distinct time intervals.The model incorporates three key fractional derivatives:the Caputo-Fabrizio fractional derivative with a non-singular kernel,the Caputo proportional constant fractional derivative with a singular kernel,and the Atangana-Baleanu fractional derivative with a non-singular kernel.We analyze the stability of the core model and apply various numerical methods to approximate the proposed crossover model.To achieve this,the approximation of Caputo proportional constant fractional derivative with Grünwald-Letnikov nonstandard finite difference method is used for the deterministic model with a singular kernel,while the Toufik-Atangana method is employed for models involving a non-singular Mittag-Leffler kernel.Additionally,the integral Caputo-Fabrizio approximation and a two-step Lagrange polynomial are utilized to approximate the model with a non-singular exponential decay kernel.For the stochastic component,the Milstein method is implemented to approximate the stochastic differential equations.The stability and effectiveness of the proposed model and methodologies are validated through numerical simulations and comparisons with real-world cholera data from Yemen.The results confirm the reliability and practical applicability of the model,providing strong theoretical and empirical support for the approach.
文摘In this paper,we study two fractional models in the Caputo–Fabrizio sense and Atangana–Baleanu sense,in which the effects of malaria infection on mosquito biting behavior and attractiveness of humans are considered.Using Lyapunov theory,we prove the global asymptotic stability of the unique endemic equilibrium of the integer-order model,and the fractional models,whenever the basic reproduction number R0 is greater than one.By using fixed point theory,we prove existence,and conditions of the uniqueness of solutions,as well as the stability and convergence of numerical schemes.Numerical simulations for both models,using fractional Euler method and Adams–Bashforth method,respectively,are provided to confirm the effectiveness of used approximation methods for different values of the fractional-orderγ.
