An optimizing method for designing the wireless power receiving coil(RC)is proposed in this paper to address issues such as insufficient and fluctuating power supply in the near-infrared capsule robot.An elec-tromagne...An optimizing method for designing the wireless power receiving coil(RC)is proposed in this paper to address issues such as insufficient and fluctuating power supply in the near-infrared capsule robot.An elec-tromagnetic and circuit analysis is conducted to establish the magnetic induction intensity and equivalent circuit models for the wireless power transmission system.Combining these models involves using the number of layers in each dimension as the optimization variable.Constraints are imposed based on the normalized standard deviation of the receiving-end load power and spatial dimensions.At the same time,the optimization objective aims to maximize the average power of the receiving-end load.This process leads to formulating an optimization model for the RC.Finally,three-dimensional RCs with three different sets of parameters are wound,and the receiving-end load power of these coils is experimentally tested under various drive currents.The experimental values of the receiving-end load power exhibit a consistent trend with theoretical values,with experimental values consistently lower than theoretical values.The optimized coil parameters are determined by conducting comparative exper-iments,with a theoretical value of 4.6%for the normalized standard deviation of the receiving-end load power and an average experimental value of 9.6%.The study addressed the power supply issue of near-infrared capsule robots,which is important for early diagnosing and treating gastrointestinal diseases.展开更多
Capsule Robots(CRs)with active locomotion improve on the inefficiency of passive locomotion in capsule endoscopes,showing great potential for clinical use.However,despite the development of various CR types,efficient ...Capsule Robots(CRs)with active locomotion improve on the inefficiency of passive locomotion in capsule endoscopes,showing great potential for clinical use.However,despite the development of various CR types,efficient locomotion and functional integration remain challenges due to space limitations and increasing demands.Additionally,many CRs are overly complex,so simplifying their structure while maintaining functionality is essential.This paper presents a novel magnetically actuated CR with two internal permanent magnets for oscillating locomotion and anchoring,along with a Shape Memory Alloy(SMA)-driven actuator for biopsy sampling.Compared to existing CRs,this design simplifies the structure while ensuring biopsy functionality and leaving space for a micro-CCD.The robot’s dynamics are modeled to guide its structural design and locomotion strategy.SMA characteristics are also examined to optimize the biopsy module’s parameters,improving efficiency and success rates.The CR undergoes experiments to assess safety,locomotion performance,and functionality,with results showing stable steering,and advantages in driving height,speed,and accuracy.Finally,the CR’s biopsy capabilities are validated in a gastric model and ex vivo stomach.This work offers a novel solution for gastrointestinal disease diagnosis and treatment,enhancing the application of CRs in biomedical engineering.展开更多
Wireless capsule endoscopy(WCE)has the potential to fully replace conventional wired counterparts for its low invasiveness.Recent studies have attempted to expand the functions of capsules toward this goal.However,lim...Wireless capsule endoscopy(WCE)has the potential to fully replace conventional wired counterparts for its low invasiveness.Recent studies have attempted to expand the functions of capsules toward this goal.However,limitations in space and energy supply have resulted in the inability to perform multiple diagnostic and treatment tasks using a single capsule.In this study,we developed a dual-functional capsule robot(DFCR)for drug delivery and tissue biopsy based on magnetic torsion spring technology.The delivery module was shown to rotate the push rod with a thrust of 894 mN to release approximately 0.3 mL of semisolid drug.The biopsy module used a built-in blade to cut tissue with a shear stress of 22.87 MPa,producing a sample of approximately 1.8 mm3.Additionally,a five-degree-of-freedom permanent magnet drive system was developed.By adjusting the strength of the unidirectional magnetic field generated by an external magnet,the capsule can be wirelessly controlled to sequentially trigger the two functions.Ex vivo tests on porcine stomachs confirmed the feasibility of the prototype capsule(12 mm in diameter and 45 mm in length)in active movement,medication,and tissue biopsy.The newly developed DFCR further expands the clinical application prospects of WCE robots in minimally invasive surgery.展开更多
A two-dimensional rectangular solenoid transmitting coil is proposed to address the problem that the three-dimensional receiving coil occupies excessive space inside the capsule robot.The transmitting coil consists of...A two-dimensional rectangular solenoid transmitting coil is proposed to address the problem that the three-dimensional receiving coil occupies excessive space inside the capsule robot.The transmitting coil consists of two pairs of rectangular solenoid coils distributed radially along the human body.By changing the direction of current flow,it can generate a two-dimensional magnetic field covering the whole central plane.Firstly,the working mechanism of the wireless power transfer system is introduced,and then the spatial electromagnetic field generated by the transmitting coil is analyzed through both mathematical calculations and finite element simulations.Finally,an experimental platform is built to determine the optimal resonant frequency of the system and validate its feasibility based on the power transfer efficiency and the receiving power.The experimental results demonstrate that when the receiving coil is located at the center of the coil pair,the receiving power is 1416 mW and the power transfer efficiency is 3.96%.Additionally,when the receiving coil operates in the central plane,it can receive sufficient energy regardless of the orientation.展开更多
Steering control of a capsule robot in curve environment by magnetic navigation is not yet solved completely.A petal-shaped capsule robot with less steering resistance based on multiple wedge effects is presented,and ...Steering control of a capsule robot in curve environment by magnetic navigation is not yet solved completely.A petal-shaped capsule robot with less steering resistance based on multiple wedge effects is presented,and an optimization method with two processes for determining the orientation of a pre-applied universal magnetic spin vector is proposed.To realize quick and non-contact steering swimming,a fuzzy comprehensive evaluation method for optimizing the steering driving angle is presented based on two evaluation indexes including the average steering speed and the average steering trajectory deviation,achieving the initial optimal orientation of a universal magnetic spin vector.To further reduce robotic magnetic vibration,a main target method for optimizing its final orientation,which is used for fine adjustment,is employed under the constrains of the magnetic moments.Swimming experimental results in curve pipe verified the effectiveness of the optimization method,which can be effectively used to realize non-contact steering swimming of the petal-shaped robot and reduce its vibration.展开更多
The existing wireless power transfer(WPT)systems for gastrointestinal capsule robot have the prob-lems of small coupling coefficient and low power transmission efficiency(PTE).The reasons are due to the long distance ...The existing wireless power transfer(WPT)systems for gastrointestinal capsule robot have the prob-lems of small coupling coefficient and low power transmission efficiency(PTE).The reasons are due to the long distance between the transmitting coil and the receiving coil and the large difference in size.A new type of WPT system is designed,which uses three sets of small coil pairs to form a power supply unit(PSU),and utilizes multiple PSUs to form a multi-coil WPT system.Compared with single-coil system,the multi-coil system can achieve higher power utilization by switching between PSUs,instead of opening all PSUs.ANSYS Maxwell is used to perform finite element modeling on the PSU,analyzing the characteristics of the transmitting magnetic field.The results of the experiment show that when the distance between the small coil pairs in the PSU is 180mm,the magnetic field has relatively good uniformity,and the magnetic strength change relative to the center point is less than 5%.The average received power of the system is greater than 800mW,and the PTE is up to 5.1%.展开更多
Based on the critical gap phenomenon of the intestinal capsule robot,a variable-diameter capsule robot with radial gap self-compensation is developed in this paper.With the functional variation principle,a fluid dynam...Based on the critical gap phenomenon of the intestinal capsule robot,a variable-diameter capsule robot with radial gap self-compensation is developed in this paper.With the functional variation principle,a fluid dynamic pressure model satisfying the boundary conditions of the outer surface of capsule robot with screw blades is derived.The critical gap phenomenon is studied theoretically and experimentally based on the end effect and the dynamic balance characteristics of the fluid on the surface of capsule robot.The concept of start-up rotation speed is defined,the relationship between the start-up rotation speed and the spiral parameters of capsule robot is investigated.The strategy for implementing drive and control on several capsule robots under the same rotational magnetic field is proposed,and by defining the start-up curves of several capsule robots with the similar motion regulation as the objective functions,genetic algorithm is employed to optimize the spiral parameters of several capsule robots.Experiments have shown that the proposed drive and control strategy for several capsule robots can be implemented effectively.It has a good prospect of application inside intestine to realize the drive and control on several capsule robots for different medical purposes.展开更多
For realizing non-contact steering swimming of a capsule robot in curved environment filled with viscous liquid, based on spa- tial orthogonal superposition theorem of alternating magnetic vectors, an innovative physi...For realizing non-contact steering swimming of a capsule robot in curved environment filled with viscous liquid, based on spa- tial orthogonal superposition theorem of alternating magnetic vectors, an innovative physical method is proposed, which em- ploys three-axis orthogonal square Helmholtz coils fed with three phase sine currents to create a universal uniform magnetic spin vector as energy source. According to the antiphase sine current superposition theorem generalized in this paper, an effec- tive control method for successively adjusting the orientation and the rotating direction of the universal magnetic spin vector is proposed. For validating its feasibility and controllability, three-axis Helmholtz coils, power source and an innovative capsule robot prototype were manufactured, experiments were conducted in both spiral pipe and animal intestine. It was demonstrated that the orientation and the rotational direction of the universal uniform-magnetic spin vector can be adjusted successively through digital control and steering swimming of the capsule robot in spiral intestine can be achieved successfully. The breakthrough of the universal rotating uniform-magnetic vector will push forward the development of modern physics and biomedical engineering展开更多
The micro-systems used for in vivo physical inspection have many advantages over traditional methods. In order to aid diagnosis of gastrointestinal (GI) motility disorders, a capsule is developed for GI pressure and p...The micro-systems used for in vivo physical inspection have many advantages over traditional methods. In order to aid diagnosis of gastrointestinal (GI) motility disorders, a capsule is developed for GI pressure and pH inspection. Localization of the capsule in GI tract with time is a necessary condition for subsequent data analysis and medical diagnosis. It is also a common problem facing all in vivo mobile micro-systems. An approach of segment localization by utilizing some key points along GI tract is proposed. A portable ultrasonic detecting device was designed for this purpose. Experiments under conditions similar to GI tract were carried out and the results proved the effectiveness and reliability of this method and the device.展开更多
According to the anti-phase sine current superposition theorem, the orientation, the magnetic flux density, the angular speed and the rotational direction of the spatial universal rotating magnetic field (SURMF) can...According to the anti-phase sine current superposition theorem, the orientation, the magnetic flux density, the angular speed and the rotational direction of the spatial universal rotating magnetic field (SURMF) can be controlled within the tri-axial orthogonal square Helmholtz coils (TOSHC). Nevertheless, three coupling direction angles of the normal vector of the SURMF in the Descartes coordinate system cannot be separately controlled, thus the adjustment of the orientation of the SURMF is difficult and the flexibility of the robotic posture control is restricted. For the dimension reduction and the decoupling of control variables, the orthogonal transformation operation theorem of the SURMF is proposed based on two independent rotation angular variables, which employs azimuth and altitude angles as two variables of the three-phase sine current superposition formula derived by the orthogonal rotation inverse transformation. Then the unique control rules of the orientation and the rotational direction of the SURMF are generalized in each spatial quadrant, thus the scanning of the normal vector of the SURMF along the horizontal or vertical direction can be achieved through changing only one variable, which simplifies the control process of the orientation of the SURMF greatly. To validate its feasibility and maneuverability, experiments were conducted in the animal intestine utilizing the innovative dual hemisphere capsule robot (DHCR) with active and passive modes. It was demonstrated that the posture adjustment and the steering rolling locomotion of the DHCR can be realized through single variable control, thus the orthogonal transformation operation theorem makes the control of the orientation of the SURMF convenient and flexible significantly. This breakthrough will lay a foundation for the human-machine interaction control of the SURMF.展开更多
基金the Project of the Science and Technology Commission of Shanghai Municipality(No.20142201300)the National Facility for Translational Medicine(Shanghai)Open Project Foundation(No.TMSK-2021-302)the China Postdoctoral Science Foundation(No.2023M732267)。
文摘An optimizing method for designing the wireless power receiving coil(RC)is proposed in this paper to address issues such as insufficient and fluctuating power supply in the near-infrared capsule robot.An elec-tromagnetic and circuit analysis is conducted to establish the magnetic induction intensity and equivalent circuit models for the wireless power transmission system.Combining these models involves using the number of layers in each dimension as the optimization variable.Constraints are imposed based on the normalized standard deviation of the receiving-end load power and spatial dimensions.At the same time,the optimization objective aims to maximize the average power of the receiving-end load.This process leads to formulating an optimization model for the RC.Finally,three-dimensional RCs with three different sets of parameters are wound,and the receiving-end load power of these coils is experimentally tested under various drive currents.The experimental values of the receiving-end load power exhibit a consistent trend with theoretical values,with experimental values consistently lower than theoretical values.The optimized coil parameters are determined by conducting comparative exper-iments,with a theoretical value of 4.6%for the normalized standard deviation of the receiving-end load power and an average experimental value of 9.6%.The study addressed the power supply issue of near-infrared capsule robots,which is important for early diagnosing and treating gastrointestinal diseases.
基金supported in part by the National Key R&D Program of China(Grant number 2023YFB4705600)in part by the Natural Science Foundation of Heilongjiang Province of China(Grant number YQ2024F011)in part by the Pre-research Task of State Key Laboratory of Robotics and Systems(HIT)(Grant number SKLRS202419B).
文摘Capsule Robots(CRs)with active locomotion improve on the inefficiency of passive locomotion in capsule endoscopes,showing great potential for clinical use.However,despite the development of various CR types,efficient locomotion and functional integration remain challenges due to space limitations and increasing demands.Additionally,many CRs are overly complex,so simplifying their structure while maintaining functionality is essential.This paper presents a novel magnetically actuated CR with two internal permanent magnets for oscillating locomotion and anchoring,along with a Shape Memory Alloy(SMA)-driven actuator for biopsy sampling.Compared to existing CRs,this design simplifies the structure while ensuring biopsy functionality and leaving space for a micro-CCD.The robot’s dynamics are modeled to guide its structural design and locomotion strategy.SMA characteristics are also examined to optimize the biopsy module’s parameters,improving efficiency and success rates.The CR undergoes experiments to assess safety,locomotion performance,and functionality,with results showing stable steering,and advantages in driving height,speed,and accuracy.Finally,the CR’s biopsy capabilities are validated in a gastric model and ex vivo stomach.This work offers a novel solution for gastrointestinal disease diagnosis and treatment,enhancing the application of CRs in biomedical engineering.
基金supported by the National Natural Science Foundation of China(No.52105072)Zhejiang Provincial Natural Science Foundation of China(No.LZ24E050004)+2 种基金Jiangsu Provincial Outstanding Youth Program(No.BK20230072)a grant from Suzhou Industrial Foresight and Key Core Technology Project(No.SYC2022044)grants from Jiangsu Qinglan Project and Jiangsu 333 High-level Talents.
文摘Wireless capsule endoscopy(WCE)has the potential to fully replace conventional wired counterparts for its low invasiveness.Recent studies have attempted to expand the functions of capsules toward this goal.However,limitations in space and energy supply have resulted in the inability to perform multiple diagnostic and treatment tasks using a single capsule.In this study,we developed a dual-functional capsule robot(DFCR)for drug delivery and tissue biopsy based on magnetic torsion spring technology.The delivery module was shown to rotate the push rod with a thrust of 894 mN to release approximately 0.3 mL of semisolid drug.The biopsy module used a built-in blade to cut tissue with a shear stress of 22.87 MPa,producing a sample of approximately 1.8 mm3.Additionally,a five-degree-of-freedom permanent magnet drive system was developed.By adjusting the strength of the unidirectional magnetic field generated by an external magnet,the capsule can be wirelessly controlled to sequentially trigger the two functions.Ex vivo tests on porcine stomachs confirmed the feasibility of the prototype capsule(12 mm in diameter and 45 mm in length)in active movement,medication,and tissue biopsy.The newly developed DFCR further expands the clinical application prospects of WCE robots in minimally invasive surgery.
基金the National Natural Science Foundation of China(Nos.62273225,81971767,62103267 and 62103263)。
文摘A two-dimensional rectangular solenoid transmitting coil is proposed to address the problem that the three-dimensional receiving coil occupies excessive space inside the capsule robot.The transmitting coil consists of two pairs of rectangular solenoid coils distributed radially along the human body.By changing the direction of current flow,it can generate a two-dimensional magnetic field covering the whole central plane.Firstly,the working mechanism of the wireless power transfer system is introduced,and then the spatial electromagnetic field generated by the transmitting coil is analyzed through both mathematical calculations and finite element simulations.Finally,an experimental platform is built to determine the optimal resonant frequency of the system and validate its feasibility based on the power transfer efficiency and the receiving power.The experimental results demonstrate that when the receiving coil is located at the center of the coil pair,the receiving power is 1416 mW and the power transfer efficiency is 3.96%.Additionally,when the receiving coil operates in the central plane,it can receive sufficient energy regardless of the orientation.
基金Supported by National Natural Science Foundation of China(Grant Nos.60875064,61175102,51277018)
文摘Steering control of a capsule robot in curve environment by magnetic navigation is not yet solved completely.A petal-shaped capsule robot with less steering resistance based on multiple wedge effects is presented,and an optimization method with two processes for determining the orientation of a pre-applied universal magnetic spin vector is proposed.To realize quick and non-contact steering swimming,a fuzzy comprehensive evaluation method for optimizing the steering driving angle is presented based on two evaluation indexes including the average steering speed and the average steering trajectory deviation,achieving the initial optimal orientation of a universal magnetic spin vector.To further reduce robotic magnetic vibration,a main target method for optimizing its final orientation,which is used for fine adjustment,is employed under the constrains of the magnetic moments.Swimming experimental results in curve pipe verified the effectiveness of the optimization method,which can be effectively used to realize non-contact steering swimming of the petal-shaped robot and reduce its vibration.
基金the National Natural Science Founda-tion of China(Nos.61673271 and 81971767)the Shang-hai Research Project(Nos.19441910600,19441913800 and 19142203800)the Project of Institute of Medical Robotics,Shanghai Jiao Tong University(No.IMR2018KY05)。
文摘The existing wireless power transfer(WPT)systems for gastrointestinal capsule robot have the prob-lems of small coupling coefficient and low power transmission efficiency(PTE).The reasons are due to the long distance between the transmitting coil and the receiving coil and the large difference in size.A new type of WPT system is designed,which uses three sets of small coil pairs to form a power supply unit(PSU),and utilizes multiple PSUs to form a multi-coil WPT system.Compared with single-coil system,the multi-coil system can achieve higher power utilization by switching between PSUs,instead of opening all PSUs.ANSYS Maxwell is used to perform finite element modeling on the PSU,analyzing the characteristics of the transmitting magnetic field.The results of the experiment show that when the distance between the small coil pairs in the PSU is 180mm,the magnetic field has relatively good uniformity,and the magnetic strength change relative to the center point is less than 5%.The average received power of the system is greater than 800mW,and the PTE is up to 5.1%.
基金supported by National Natural Science Foundation of China(Grant Nos. 60675054, 60875064)Self-Planned Task of State Key Laboratory of Robotics and System (HIT) (Grant No. SKLRS200903B)
文摘Based on the critical gap phenomenon of the intestinal capsule robot,a variable-diameter capsule robot with radial gap self-compensation is developed in this paper.With the functional variation principle,a fluid dynamic pressure model satisfying the boundary conditions of the outer surface of capsule robot with screw blades is derived.The critical gap phenomenon is studied theoretically and experimentally based on the end effect and the dynamic balance characteristics of the fluid on the surface of capsule robot.The concept of start-up rotation speed is defined,the relationship between the start-up rotation speed and the spiral parameters of capsule robot is investigated.The strategy for implementing drive and control on several capsule robots under the same rotational magnetic field is proposed,and by defining the start-up curves of several capsule robots with the similar motion regulation as the objective functions,genetic algorithm is employed to optimize the spiral parameters of several capsule robots.Experiments have shown that the proposed drive and control strategy for several capsule robots can be implemented effectively.It has a good prospect of application inside intestine to realize the drive and control on several capsule robots for different medical purposes.
基金supported by the National Natural Science Foundation of China (Grant Nos. 60875064,61175102,and 51277018)
文摘For realizing non-contact steering swimming of a capsule robot in curved environment filled with viscous liquid, based on spa- tial orthogonal superposition theorem of alternating magnetic vectors, an innovative physical method is proposed, which em- ploys three-axis orthogonal square Helmholtz coils fed with three phase sine currents to create a universal uniform magnetic spin vector as energy source. According to the antiphase sine current superposition theorem generalized in this paper, an effec- tive control method for successively adjusting the orientation and the rotating direction of the universal magnetic spin vector is proposed. For validating its feasibility and controllability, three-axis Helmholtz coils, power source and an innovative capsule robot prototype were manufactured, experiments were conducted in both spiral pipe and animal intestine. It was demonstrated that the orientation and the rotational direction of the universal uniform-magnetic spin vector can be adjusted successively through digital control and steering swimming of the capsule robot in spiral intestine can be achieved successfully. The breakthrough of the universal rotating uniform-magnetic vector will push forward the development of modern physics and biomedical engineering
文摘The micro-systems used for in vivo physical inspection have many advantages over traditional methods. In order to aid diagnosis of gastrointestinal (GI) motility disorders, a capsule is developed for GI pressure and pH inspection. Localization of the capsule in GI tract with time is a necessary condition for subsequent data analysis and medical diagnosis. It is also a common problem facing all in vivo mobile micro-systems. An approach of segment localization by utilizing some key points along GI tract is proposed. A portable ultrasonic detecting device was designed for this purpose. Experiments under conditions similar to GI tract were carried out and the results proved the effectiveness and reliability of this method and the device.
基金supported by the National Natural Science Foundation of China (Grant Nos. 51277018, 61175102, & 51475115)the Open Fund of the State Key Laboratory of Mechanical Transmissions (Grant No.SKLMT-KFKT-201509)
文摘According to the anti-phase sine current superposition theorem, the orientation, the magnetic flux density, the angular speed and the rotational direction of the spatial universal rotating magnetic field (SURMF) can be controlled within the tri-axial orthogonal square Helmholtz coils (TOSHC). Nevertheless, three coupling direction angles of the normal vector of the SURMF in the Descartes coordinate system cannot be separately controlled, thus the adjustment of the orientation of the SURMF is difficult and the flexibility of the robotic posture control is restricted. For the dimension reduction and the decoupling of control variables, the orthogonal transformation operation theorem of the SURMF is proposed based on two independent rotation angular variables, which employs azimuth and altitude angles as two variables of the three-phase sine current superposition formula derived by the orthogonal rotation inverse transformation. Then the unique control rules of the orientation and the rotational direction of the SURMF are generalized in each spatial quadrant, thus the scanning of the normal vector of the SURMF along the horizontal or vertical direction can be achieved through changing only one variable, which simplifies the control process of the orientation of the SURMF greatly. To validate its feasibility and maneuverability, experiments were conducted in the animal intestine utilizing the innovative dual hemisphere capsule robot (DHCR) with active and passive modes. It was demonstrated that the posture adjustment and the steering rolling locomotion of the DHCR can be realized through single variable control, thus the orthogonal transformation operation theorem makes the control of the orientation of the SURMF convenient and flexible significantly. This breakthrough will lay a foundation for the human-machine interaction control of the SURMF.
