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Feed nutritional value of brewers’ spent grain residue resulting from protease aided protein removal 被引量:3
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作者 Yizhao Shen Ranithri Abeynayake +4 位作者 Xin Sun Tao Ran Jianguo Li Lingyun Chen Wenzhu Yang 《Journal of Animal Science and Biotechnology》 SCIE CAS CSCD 2020年第1期147-156,共10页
Background:This study was conducted to evaluate the feed nutritional value of brewers’spent grain(BSG)residue resulting from protease aided protein removal.The nutritional value was measured as nutrient content,gas p... Background:This study was conducted to evaluate the feed nutritional value of brewers’spent grain(BSG)residue resulting from protease aided protein removal.The nutritional value was measured as nutrient content,gas production,nutrient digestibility and fermentation characteristics in batch culture.Results:Protein extraction process decreased content of crude protein but concentrated the neutral detergent fibre(NDF)and ferulic acid in BSG residue.The changes in the chemical composition of BSG residue varied with enzyme and enzyme dosage.Digestibility of dry matter(DMD)and NDF of residue differed among proteases.Increasing alcalase dosage linearly decreased DMD,whereas,the DMD linearly increased as everlase or flavourzyme dosage increased.Compared with BSG,the DMD,gas production and fermentation acid concentration of BSG residues were lower,whereas NDF digestibility was higher.Conclusions:The substantially increased NDF content and improved in vitro NDF digestibility due to protease hydrolysis suggest that BSG residue can be potentially exploited as a viable fibre source for ruminant feeding. 展开更多
关键词 BATCH culture brewers’spent GRAIN Chemical composition FERMENTATION PROTEASE HYDROLYSIS
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Properties of Bacillus species Cellulase Produced Using Cellulose from Brewers Spent Grain (BSG) as Substrate 被引量:1
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作者 Frank Anayo Orji Ekaette Nduka Dike +10 位作者 Adekunle Kolawole Lawal Abdulateef Omoniyi Sadiq Yewande Suberu Ariyo Caleb Famotemi Agatha Isioma Ugbana Folake Fashola Blossom Ita Samuel Olakiitan Olatope Emoleila Ejiya Itoandoan Abimbola Olajumoke Adefiranye Gloria Nwakaegho Elemo 《Advances in Bioscience and Biotechnology》 2016年第3期142-148,共7页
The properties of extracellular cellulase obtained from Bacillus species (FIIRO Strain B223) on supplying cellulose from Brewers Spent Grain (BSG) were studied. Generally, a crude cellulase activity between 11,757 Uni... The properties of extracellular cellulase obtained from Bacillus species (FIIRO Strain B223) on supplying cellulose from Brewers Spent Grain (BSG) were studied. Generally, a crude cellulase activity between 11,757 Units to 13,930 Units was observed for both sources of carbon (BSG and crystalline cellulose). The optimum pH and temperature of 5.0, and 30°C - 40°C for both sources of carbon was observed. Heavy metals such as copper, zinc, and iron inhibited the activities of B223 cellulase while the cellulase activities on alkaline earth metal (manganese) were moderate. The co-factor behaviour of manganese ion was also established. Local production of cellulase in Nigeria using local raw materials such as Brewers Spent Grain reduces enzyme cost;cost of finished products and increases gross domestic products. 展开更多
关键词 CELLULASE Bacillus species Crude Activities Temperature pH Tolerance brewers Spent Grains (BSG)
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Dairy Farming Conditions and Utilization Levels of Liquid Brewers’ Yeast in Kenya
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作者 Peter Alphonce Obuong Alaru Alfred Anakalo Shitandi +1 位作者 Symon Maina Mahungu John Muasya Kilumba Muia 《Open Journal of Animal Sciences》 CAS 2023年第1期1-19,共19页
Dairy production plays an integral part in supporting smallholder farmers’ livelihoods. The desire to increase the number of dairy cattle is not feasible due to the reduced output of feed resources occasioned by clim... Dairy production plays an integral part in supporting smallholder farmers’ livelihoods. The desire to increase the number of dairy cattle is not feasible due to the reduced output of feed resources occasioned by climate change. Consequently, the need to increase productivity per cow is inevitable. Conventional protein supplements are costly;hence, the need to explore affordable nutrientdense alternative feed resources. Liquid brewers’ yeast (LBY), a by-product of the brewing industry, is a rich protein supplement in dairy production. This study aimed to assess the dairy farming conditions and utilization levels of LBY as a feed supplement in Githunguri Sub-county, Kiambu. Semi-structured questionnaires were administered to 457 dairy farmers in a cross-sectional survey. The findings revealed that most farmers (94.2%) fed their cattle on established forage/fodder and crop residues with supplementation. Even though 53.1% of the respondents were aware of the use of LBY, only 30.6% utilized it to supplement dairy cows, most of whom (96.0%) used it fresh without preservation. Membership in farmers’ organizations increased awareness of LBY (r = 0.732). Principal component analysis indicated that the benefits of using LBY outweigh the challenges involved with a loading matrix of 0.891 - 0.954 and 0.681 - 0.807, respectively. The low adoption and use levels of LBY as a source of protein supplements were due to low awareness. There is a need for concerted efforts by stakeholders in the industry to increase farmers’ knowledge base on the utilization and effectiveness of LBY in dairy production. 展开更多
关键词 Dairy-Production Liquid brewers Yeast PROTEIN SUPPLEMENT
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Impact of Storage Temperature on Microbial Diversity and Probiotic Effect of Liquid Brewers’ Yeast
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作者 Peter Alphonce Obuong Alaru Alfred Anakalo Shitandi +1 位作者 Symon Maina Mahungu John Muasya Kilumba Muia 《Open Journal of Animal Sciences》 2024年第3期168-182,共15页
Using probiotics as animal feed additives instead of antibiotics is gaining momentum to avert adverse negative effects on human health. Liquid brewers yeast (LBY) is an industrial by-product containing probiotic micro... Using probiotics as animal feed additives instead of antibiotics is gaining momentum to avert adverse negative effects on human health. Liquid brewers yeast (LBY) is an industrial by-product containing probiotic microorganisms and is also used as a protein supplement for dairy animals. Nevertheless, value chain actors lack of appropriate handling practices compromises the by-products quality and safety. This study aimed to determine the effect of variation in temperature on microbial diversity and probiotic effects during the storage time of LBY sampled from distributors and farmers from Githunguri sub-county of Kenya. The samples were stored at 20C, 25C and 30C, then tested on 0, 5, 10, 15 and 20 days. The studys parameters involved determining the pH levels, lactic acid bacteria (LAB), total coliform count (TCC), mould, and yeast in LBY. The rate (k) of the reaction kinetics model was used to extrapolate the expected probiotic shelf life. The LAB and yeast populations were reduced in a first-order reaction at all storage temperatures. The rate of reduction in the numbers of LAB reduced with an increase in temperature (k = 0.019 and 0.023) at 20C and 30C, respectively. Yeasts highest rate of growth reduction was 25C (k = 0.009) and least at 30C (k = 0.043). The minimum effective concentration for probiotics of 106 CFU/mL needed to observe the beneficial physiological impact on farm animals was achieved between 34.9 and 35.5 days at the tested storage temperatures. The study provides insight into the unexploited low-cost probiotic potential of LBY in dairy production. Conversely, handling practices and environmental microbial contamination along the value chain can compromise product quality and safety. There is a need to advocate its use in dairy for improved productivity and sensitize farmers to appropriate hygienic measures along the LBY value chain. 展开更多
关键词 Liquid brewers Yeast Microbial Diversity PROBIOTICS Shelf Life
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Techniques Optimization of Combined Enzymatic Hydrolysis on Brewers' Spent Grain from Novozymes
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作者 Zhaoxia Li Jinlong Yan +1 位作者 Dan Shen Cheng Ding 《Journal of Life Sciences》 2012年第11期1232-1236,共5页
Purpose: To extract protein, decrease the cellulose and facilitate the digestion and absorption of brewers' spent grain by animal. Topic: Discuss and optimize the hydrolysis conditions of the combined enzymatic hyd... Purpose: To extract protein, decrease the cellulose and facilitate the digestion and absorption of brewers' spent grain by animal. Topic: Discuss and optimize the hydrolysis conditions of the combined enzymatic hydrolysis by Novozymes. Method: The fresh brewers' spent grain was firstly dried, smashed and sifted. Then as indicators of the protein extraction rate in the enzyme solution and the content of cellulose in the index, the parameters of enzymatic hydrolysis, such as the solid-liquid ratio, reaction temperature, pH, enzyme dosage and reaction time, were investigated in detailed. After hydrolysis, the brewers' spent grain was put in the boiling water bath for inactivation for 15 minutes, and centrifuged, the supernatants were volume to 100 mL and the protein content was measured. After the precipitate was dried, the cellulose content was also measured. Achievements: The optimized conditions were with temperature of 50 ℃, pH 6.5, enzyme amount of 30 mg for Novozymes enzyme and 2.5 h for reaction time. Under these conditions, the protein extraction rate in the enzyme reaction reached 41.82%, and the cellulose content reached 13.90%, the degradation rate of cellulose was 18.86%. 展开更多
关键词 Brewer's grain Novozymes combined enzymatic hydrolysis PROTEIN crude fiber.
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南极中山站长期(1993-2023年)再分析臭氧总量地基观测验证及趋势
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作者 郑广惠 巨天珍 +2 位作者 丁明虎 卞林根 郑向东 《空间科学学报》 北大核心 2026年第1期86-96,共11页
基于南极中山站1993-2023年Brewer光谱仪地基观测大气臭氧总量(Ω),对再分析数据MERRA2和ERA5的臭氧总量进行验证、评估和趋势分析.研究发现,再分析数据与地基测值在反映南极臭氧洞及臭氧总量季节变化方面是一致的.日均MERRA2和ERA5的... 基于南极中山站1993-2023年Brewer光谱仪地基观测大气臭氧总量(Ω),对再分析数据MERRA2和ERA5的臭氧总量进行验证、评估和趋势分析.研究发现,再分析数据与地基测值在反映南极臭氧洞及臭氧总量季节变化方面是一致的.日均MERRA2和ERA5的臭氧总量差异浓度值(ΔΩ)分别为–2.0±9.6 DU和3.2±7.8DU,相对差异分布均呈随机特征. 1993-2004年和2005-2023年两个时段的臭氧洞(地基Ω≤220 DU)期间,MERRA2的相对差异百分比ΔR均值分别为6.9%±4.6%和–0.4%±2.3%,而ERA5则分别为4.6%±2.0%和6.4%±3.1%;随着太阳天顶角θ的上升, MERRA2与ERA5的ΔR在1993-2004年分别呈现总体幅度为3%和2%的上升,而在2005-2023年则分别呈–2%下降和2%上升;2005-2023年的再分析臭氧总量数据质量优于1993-2004年.经Brewer光谱仪测值订正后的再分析数据均表现出Ω的恢复态势,其中ERA5的恢复速率每10年为1.3 DU.再分析数据在被地基验证和订正之前应慎用于评估南极大气臭氧总量长期趋势变化.地基臭氧总量观测时数虽然受太阳天顶角或天气影响而远低于再分析数据,但对再分析数据的验证是评估臭氧总量长期变化的关键依据. 展开更多
关键词 臭氧总量 Merr2-TOC ERA5-TOC Brewer光谱仪 南极中山站
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南极中山站高太阳天顶角时地基臭氧总量观测比较
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作者 郑广惠 巨天珍 +2 位作者 丁明虎 卞林根 郑向东 《气象学报》 北大核心 2026年第1期159-171,共13页
中国南极中山站(69.37°S,76.38°E)每年5—7月最低太阳天顶角(SZA)≥80°限制了利用太阳直射光(DS)开展大气臭氧柱总量(TOC)的观测,进而影响了对秋、冬季乃至全年TOC变化的准确认识。将南极中山站2009—2023年高太阳天顶角... 中国南极中山站(69.37°S,76.38°E)每年5—7月最低太阳天顶角(SZA)≥80°限制了利用太阳直射光(DS)开展大气臭氧柱总量(TOC)的观测,进而影响了对秋、冬季乃至全年TOC变化的准确认识。将南极中山站2009—2023年高太阳天顶角(SZA≥80°)时4种(Brewer光谱仪的DS即TOC_(DS≥80°)、聚焦太阳(FS)即TOC_(FS≥80°)、聚焦月球(FM)即TOC_(FM)和SAOZ曙暮光光谱仪即TOC_(SAOZ))观测结果以SZA在[72°,80°)时Brewer光谱仪的DS观测值(TOC_(DS[72,80°)))为参考进行了比较。结果显示,杂散光使得TOCDS≥80°观测值在SZA为[81°,81.5°)时平均差异和相对差异分别偏低(5.5±9.5(1σ)) DU和(2.1±4.1(1σ))%;TOC_(FS≥80°)观测值在SZA为[80°,84.5°)时平均差异和相对差异分别偏高(2.8±4.3(1σ)) DU和(1.75±4.3(1σ))%,臭氧层质量数(μ)随SZA增大而偏低是TOC_(FS≥80°)观测值偏高的原因;TOC_(FM)观测值平均差异和相对差异分别偏低(6.8±16.7(1σ)) DU和(2.2±6.8(1σ))%,TOC_(SAOZ)对应的差异则分别偏低(12.1±12.9(1σ))DU和(4.4%±5.0(1σ))%。曙暮光在大气中较长的传输光程及TOC随纬度增高而增大导致TOC_(SAOZ)明显偏低。“臭氧洞”期间TOC昼夜急剧变化造成DS、FS和FM观测值与参考值的差异大于非“臭氧洞”期。建议SZA≥80°时优先应用FS观测,FM是极夜期间唯一有效的TOC观测途径。综合4种高SZA情形下的地基TOC观测可确定:南极中山站“臭氧洞”开始于8月,极夜期间TOC均值270—290 DU,最低约为230 DU,表明臭氧层损耗已经发生;秋季(3月)TOC低值与北半球中高纬度9月情形相似,是南半球平流层Brewer-Dobson环流影响所致。 展开更多
关键词 高太阳天顶角 臭氧总量 臭氧洞 观测比较分析 Brewer/SAOZ光谱仪
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Protease hydrolysed brewers’spent grain bioactive extracts for applications in human health 被引量:1
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作者 Azza Silotry Naik Mila Brugiere +3 位作者 Kevin Dunne Michael Sorohan Laura Grasa Bilal Javed 《Systems Microbiology and Biomanufacturing》 2024年第3期1062-1075,共14页
About 39 million tons of Brewer’s spent grain(BSG),the main by-product of beer manufacturing,are produced annually and is used for low value applications.To valorise this rich bioresource,the present work entails bio... About 39 million tons of Brewer’s spent grain(BSG),the main by-product of beer manufacturing,are produced annually and is used for low value applications.To valorise this rich bioresource,the present work entails bioprocessing of BSG with various proteases(Novozymes)at two different concentrations(4%and 9%)to solubilise protein,carbohydrate and polyphenols from the grain and evaluate its effect on gut and brain health.The results show the highest(p<0.05)FRAP(Ferric Reducing Antioxidant Power)based antioxidant activity was obtained for Pro 5(4%:108.10±4.17μmole Trolox Equivalence(TE)/g protein,18.06±0.70μmole TE/g d.w.,which was 3.6 times higher than untreated control extracts.The highest DPPH(1,1-diphenyl-2-picrylhydrazyl)scavenging activity was obtained for the same extract(Pro 5 at 4%:0.118±0.006μg AAE/mg d.w.,9%:0.110±0.006μg AAE/mg d.w).Proximate composition showed this extract to contain the highest concentration of proteins at 21.66%±2.71,and color analysis showed the same Pro 5(4%)extract to be the darkest(L*53.73)indicating the possible presence of dark polyphenols.Anticancer screening showed Control and Pro 1 to possess cytotoxic effect against colon cancer cells with IC_(50)of 3.2 and 13.91 mg/mL,respectively.No significant activity was noted against the brain cancer cell line.Thus anti-colon cancer activity of BSG extracts highlights its potential in gut health.The observed bioactivity resulted from a combination of peptides,carbohydrates and polyphenolic compounds in the extract and warrants further characterisation for targeted nutraceutical applications. 展开更多
关键词 brewers’spent grain Protein hydrolysates ANTIOXIDANT ANTICANCER Gut health Brain health
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POX1 regulates the formation of viable but non-culturable brewer's yeast induced by iso-αacid from hops
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作者 Zengyan Wang Yang Xiao +9 位作者 Xuchen Li Zhenqing Li Yan Wang Wei He Jiayang Wang Li Liu Ting Ding Pengdong Sun Jingyuan Li Yang Deng 《Food Science and Human Wellness》 2025年第6期2415-2425,共11页
In this study,we utilized gene knockout and overexpression techniques to generate brewer's yeast strains with either a deletion or overexpression of the fatty acyl-CoA oxidase(POX1)gene.The strains studied include... In this study,we utilized gene knockout and overexpression techniques to generate brewer's yeast strains with either a deletion or overexpression of the fatty acyl-CoA oxidase(POX1)gene.The strains studied included the parental strain,the POX1 deletion strain,and the POX1 overexpression strain.These strains were exposed to iso-αacid from hops at a concentration of 300 mg/L,leading to the induction of a viable but nonculturable(VBNC)state.Our results indicated that the silencing of the POX1 gene rendered brewer's yeast cells unable to withstand the high concentration of iso-αacid stress,ultimately leading to cell death.Conversely,the overexpression of POX1 accelerated the transition of yeast cells into the VBNC state compared to the parental strain.Furthermore,we evaluated the levels of reactive oxygen species(ROS),catalase(CAT)activity,superoxide dismutase(SOD)activity,glutathione reductase(GR)activity,and the m RNA expression of genes that regulate these enzymes(the stress-inducible yeast Mpv17(SYM1)gene,CTA1,SOD1,and glutathione reductase(GLR1)gene)in brewer's yeast cells at three distinct stages:normal,short-term stress,and VBNC states.Based on these findings,it can be inferred that the formation of the VBNC state in brewer's yeast is associated with the response to oxidative stress. 展开更多
关键词 Saccharomyces cerevisiae Brewer’s yeast POX1 gene Viable but non-culturable(VBNC)state Oxidative stress
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金属价的确定方法 被引量:3
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作者 李小波 张平 《材料导报》 EI CAS CSCD 北大核心 2010年第3期102-107,共6页
按照"键中取价"的思路,综述了金属中各种键价理论的本质和方法。Pauling金属价键理论从综合性能来定价,建立了共价电子与键长的关系式;Engel-Brewer金属价键理论从键合能来确定价态;Hume-Rothery电子浓度理论从化合物的结构... 按照"键中取价"的思路,综述了金属中各种键价理论的本质和方法。Pauling金属价键理论从综合性能来定价,建立了共价电子与键长的关系式;Engel-Brewer金属价键理论从键合能来确定价态;Hume-Rothery电子浓度理论从化合物的结构来定价;余瑞璜的固体与分子经验电子理论从键距差来定价电子结构;谢佑卿的单原子理论从"能"和"形"来定价电子结构。每种理论从不同方面阐述对金属价的理解。 展开更多
关键词 键价理论Pauling Engel—Brewer Hume-Rothery固体与分子经验电子理论单原子理论
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南极中山站太阳紫外辐射测值比较 被引量:7
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作者 郑向东 程海轩 《应用气象学报》 CSCD 北大核心 2020年第4期482-493,共12页
比较分析了2017年南极中山站3种仪器测量地面太阳紫外B(UVB)波段和紫外A(UVA)波段的辐照度。以Brewer光谱仪测值为参考,国产宽波段FSUVB日射表在UVB(波段280~315 nm)的辐照度相对误差为(55±75)%,误差随大气臭氧总量的增加呈上升趋... 比较分析了2017年南极中山站3种仪器测量地面太阳紫外B(UVB)波段和紫外A(UVA)波段的辐照度。以Brewer光谱仪测值为参考,国产宽波段FSUVB日射表在UVB(波段280~315 nm)的辐照度相对误差为(55±75)%,误差随大气臭氧总量的增加呈上升趋势,但在南极"臭氧洞"期间偏低。Yankee UVB宽波段日射表在UVB(波段280~320 nm)的辐照度相对误差为(-31±22)%;国产宽波段FSUVA日射表在UVA(波段315~400 nm)的辐照度相对误差为(23±5.9)%。太阳天顶角低于80°的晴天以Tropospheric Ultraviolet Visible(TUV)辐射模式计算结果为参考时,FSUVB,Yankee UVB和FSUVA辐照度的平均相对误差分别为(30±37)%,(-22±19)%和(27±6.4)%,而Brewer相对误差未超过3.5%。国产宽波段UV日射表测值偏高,反映出波长较长的杂散光对太阳辐照度测值影响明显。 展开更多
关键词 FSUVA/FSUVB日射表 Brewer光谱仪 TUV模式计算 UV辐照度 南极中山站
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基于Brewer抽样的不放回样本追加策略下域的估计 被引量:3
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作者 李莉莉 《数理统计与管理》 CSSCI 北大核心 2017年第4期651-660,共10页
本文研究了基于Brewer抽样的不放回追加策略,给出单元的前两阶包含概率的具体计算公式,并构造联合设计下的Horvitz-Thompson估计,同时给出了模拟结果。根据模拟结果可以看出,在联合设计下域总量估计的精度比基本设计和追加设计下估计量... 本文研究了基于Brewer抽样的不放回追加策略,给出单元的前两阶包含概率的具体计算公式,并构造联合设计下的Horvitz-Thompson估计,同时给出了模拟结果。根据模拟结果可以看出,在联合设计下域总量估计的精度比基本设计和追加设计下估计量的精度高。 展开更多
关键词 Brewer抽样 样本追加策略 域估计
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青藏高原瓦里关地区大气臭氧柱总量及UV-B观测结果的特征分析 被引量:2
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作者 张晓春 郑向东 汤洁 《青海气象》 2003年第2期39-44,共6页
利用Brewer臭氧分光光谱仪对青藏高原东北部瓦里关地区的大气臭氧柱总量及太阳紫外B生物有效辐射剂量进行了连续的观测。通过对1996~1999年的资料分析表明:该地区的臭氧柱总量具有明显的年季变化特征,并存在着减少的趋势,与TOMS卫星的... 利用Brewer臭氧分光光谱仪对青藏高原东北部瓦里关地区的大气臭氧柱总量及太阳紫外B生物有效辐射剂量进行了连续的观测。通过对1996~1999年的资料分析表明:该地区的臭氧柱总量具有明显的年季变化特征,并存在着减少的趋势,与TOMS卫星的观测结果相一致;臭氧垂直廓线的Umkehr反演得出这一地区的臭氧数密度最大值出现在20~30km处,冬春季的高度低于夏季;太阳紫外B生物有效辐射剂量夏季最高可达0.4W/m^2。 展开更多
关键词 青藏高原 瓦里关地区 大气臭氧柱总量 UV-B观测 Brewer臭氧分光光谱仪 太阳紫外B生物有效辐射剂量 平流层
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Efficient Protein-based Bait Formulation for Attraction and Feeding Response of Fruit Flies (Diptera: Tephritidae) in Myanmar 被引量:1
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作者 Kyaw Lin Maung Yin Yin Mon +4 位作者 Myat Phyu Khine Khin Nyein Chan Aye Phyoe Aye Thandar Soe Aye Aye Khai 《Journal of Life Sciences》 2019年第2期18-24,共7页
Protein baitsprays were produced from many different sources for the controlling fruit flies in the integrated pest management program around the world.Here,fruit fly baits were formulated based on cost-effective bait... Protein baitsprays were produced from many different sources for the controlling fruit flies in the integrated pest management program around the world.Here,fruit fly baits were formulated based on cost-effective bait mixtures such as local jaggery,brewers spent grain(BSG),apple cider vinegar,wheat bran powder and local red wine with the fresh enzyme from papaya and pineapple.Fruit fly Baits were prepared by mixing the small amount of local detergent as insecticide.Our results indicated that the best efficient fruit fly bait for area wide integrated pest management(AW-IPM)is the BSG-based bait whereas the second efficient bait is local red wine-based bait.The highest fruit fly per trap per day(FTD)value by BSG-based bait traps was discovered.The highest female captured percentage is BSG-based bait with papaya solution.The field analysis of one week and one month old protein-based bait showed that FTD values decreased slightly while only one month old wheat bran-based bait dropped to the base.The BSG-based baits analysis is effective not only female fruit flies but also cockroaches male in Myanmar’s tropical region.Thus our results reveal that the efficient protein-based bait is the fresh BSG-based bait with papaya solution. 展开更多
关键词 Protein-based bait brewers spent grain trapping management fruit flies cockroach.
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关于滋养细胞疾病诊、治、防方面几个问题的探讨(文献复习与病例分析)
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作者 江森 李家福 《现代妇产科进展》 CSCD 1989年第1期17-21,共5页
滋养细胞疾病自400BC Hippocrates发现“dropsy of the uterus”和1700年Smellie首次涉及“hydatid and mole”以来,至1895年Marchand阐明其来源与恶性可能,嗣后Fels,Ernhart,Reossler与Zondek等发现患者尿中促性腺激素水平显著增多,用... 滋养细胞疾病自400BC Hippocrates发现“dropsy of the uterus”和1700年Smellie首次涉及“hydatid and mole”以来,至1895年Marchand阐明其来源与恶性可能,嗣后Fels,Ernhart,Reossler与Zondek等发现患者尿中促性腺激素水平显著增多,用作诊断,以及近50年来,Hertz, Ross,Lipsett,Delfs, Odell,Vaitukaitus,Hertig, Sheldon, Gore, Brewer,Park,Bagshawe, Acosta-Sison,Goldstein。 展开更多
关键词 滋养细胞疾病 绒癌 病理学检查 促性腺激素 UTERUS 绒毛膜癌 HIPPOCRATES 内分泌学 绒毛膜上皮癌 Brewer
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一些关于Brewer多项式的恒等式
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作者 马金萍 《黑龙江大学自然科学学报》 CAS 北大核心 2009年第2期168-172,共5页
Brewer多项式Vn(x,Q),n=0,1,2,…是由下列递推公式定义的:Vn(x,Q)=xVn-1(x,Q)-QVn-2(x,Q),n>2,其中V0(x,Q)=2,V1(x,Q)=x,V2(x,Q)=x2-2Q.运用第二类广义Chebyshev多项式的生成函数,研究Vn(x,Q)的算术性质,从而可以获得一些关于Brewer... Brewer多项式Vn(x,Q),n=0,1,2,…是由下列递推公式定义的:Vn(x,Q)=xVn-1(x,Q)-QVn-2(x,Q),n>2,其中V0(x,Q)=2,V1(x,Q)=x,V2(x,Q)=x2-2Q.运用第二类广义Chebyshev多项式的生成函数,研究Vn(x,Q)的算术性质,从而可以获得一些关于Brewer多项式的恒等式。 展开更多
关键词 Brewer多项式 生成函数 CHEBYSHEV多项式
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香河地基观测臭氧柱总量数据分析及臭氧变化趋势研究 被引量:5
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作者 窦鑫 张金强 +3 位作者 朱彬 郑向东 夏祥鳌 陈洪滨 《气候与环境研究》 CSCD 北大核心 2019年第2期143-151,共9页
大气臭氧变化在全球气候和环境中具有重要作用,是当今大气科学领域的重要研究对象之一。对比分析了中国科学院大气物理研究所河北香河大气综合观测试验站2014~2016年Dobson和Brewer两种臭氧总量观测仪器探测结果的一致性,并使用1979~2... 大气臭氧变化在全球气候和环境中具有重要作用,是当今大气科学领域的重要研究对象之一。对比分析了中国科学院大气物理研究所河北香河大气综合观测试验站2014~2016年Dobson和Brewer两种臭氧总量观测仪器探测结果的一致性,并使用1979~2016年Dobson观测数据分析了香河地区臭氧总量的长期变化趋势。结果表明:进行有效温度修正后,两种臭氧总量仪器观测结果一致性较好,平均偏差仅为-0.14DU(多布森单位),平均绝对偏差为8.00 DU,标准差为36.09 DU,相关系数达0.964。整体来说,两类仪器观测臭氧总量吻合较好。SO2浓度对Dobson仪器数据精度有一定影响,两组仪器数据在SO2浓度为0~0.2DU、0.2~0.4DU和>0.4DU大气条件情况下的平均偏差分别为4.8 DU、7.0 DU和8.0 DU,平均偏差随SO2浓度升高而增大。过去38年香河地区的臭氧总量季节差异性强,春、冬两季臭氧总量高,夏、秋两季臭氧总量相对低,季节变化趋势差异明显。从长期变化上看,臭氧总量变化波动有不同的周期,在4个大的时间段变化趋势不同,2000~2010年臭氧层有显著恢复,但最近几年又有变薄的趋势。 展开更多
关键词 臭氧柱总量 地基观测 Brewer观测仪器 Dobson观测仪器 一致性分析
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Assessment of Long Term UV Radiation Measured by the Brewer Spectrophotometer in Hong Kong during 1995-2005 被引量:2
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作者 T.J. Wang K.S. Lam +1 位作者 Q. Liu X.M. Wang 《Atmospheric and Climate Sciences》 2011年第1期9-17,共9页
Time series of daily UV radiation measured by the ground-based Brewer spectrophotometer #115 in Hong Kong during 1995-2005 were studied through statistics analysis, with focus on the variability and long term changes ... Time series of daily UV radiation measured by the ground-based Brewer spectrophotometer #115 in Hong Kong during 1995-2005 were studied through statistics analysis, with focus on the variability and long term changes in relation to total ozone, clouds and AOD (Aerosol Optical Depth). The 11-year mean UV daily dose is 2644±262 J/m2, with maxima(3311 J/m2) in 2000 and minima (2415 J/m2) in 2002. The data were compared with that from TOMS (Total Ozone Mapping Spectrometer) Version 8 and show general agreement between the two. However, the Brewer UV measurement is about 10% lower compared to TOMS data. Apart from the common-known strong seasonal cycle, 26 month periodical was resolved by use of wavelet analysis, which was believed to be associated with quasi-biennial oscillation (QBO) of general circulation. In cloudy days, the annual mean UV daily dose decrease 3.5% to 44.5% compared to clear days. It was also found that surface UV irradiance has close relation to air pollution. Under clear sky condition, 1% AOD increase will lead to 0.2% UV decrease. While global UV radiation increase due to the worldwide observed ozone depletion, investigations indicate that this trend is not significant in Hong Kong during the last 11 years. The possible causes can be attributed to the compensative effect from two aspects. One is the increase of UV resulting from the reduction of clouds with rate of 0.56/10 yr. The other is the decrease of UV due to the enhancement of total ozone and AOD with a rate of 4.23 DU/10 yr and 0.33/10 yr, respectively. 展开更多
关键词 UV RADIATION Brewer SPECTROPHOTOMETER TOMS Hong Kong
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聚酰亚胺彩色滤光片材料
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《液晶与显示》 CAS CSCD 1989年第6期47-47,共1页
Brewer科学公司介绍一种聚酰亚胺彩色(PIC)滤光片材料可用于高质量多色显示器、摄象机和彩色复印机。PIC能够提供均匀性和再现性极佳的色彩。用标准的正性胶设备和工艺可在这些滤光片上形成图形。用常规光刻工艺在很大的衬底上给出高的... Brewer科学公司介绍一种聚酰亚胺彩色(PIC)滤光片材料可用于高质量多色显示器、摄象机和彩色复印机。PIC能够提供均匀性和再现性极佳的色彩。用标准的正性胶设备和工艺可在这些滤光片上形成图形。用常规光刻工艺在很大的衬底上给出高的成品率。PIC具有极佳的光稳定性和热稳定性,可在苛刻的环境条件下工作。 展开更多
关键词 滤光片 Brewer 摄象机 光刻工艺 均匀性 再现性 光稳定性 环境条件 聚酞亚胺 三基色
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Variation in Brewer–Dobson Circulation During Three Sudden Stratospheric Major Warming Events in the 2000s
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作者 Mengchu TAO Yi LIU Yuli ZHANG 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2017年第12期1415-1425,共11页
As the strongest subseasonal atmospheric variability during boreal winter, three remarkable sudden stratospheric major warming(SSW) events in the 2000 s are investigated in terms of the Brewer–Dobson circulation(BDC)... As the strongest subseasonal atmospheric variability during boreal winter, three remarkable sudden stratospheric major warming(SSW) events in the 2000 s are investigated in terms of the Brewer–Dobson circulation(BDC) response. Our study shows that the changes of cross-isentropic velocity during the SSWs are not only confined to the polar region, but also extend to the whole Northern Hemisphere: enhanced descent in the polar region, as well as enhanced ascent in the tropics. When the acceleration of the deep branch of the BDC descends to the middle stratosphere, its strength rapidly decreases over a period of one to two weeks. The acceleration of the deep branch of the BDC is driven by the enhanced planetary wave activity in the mid-to-high-latitude stratosphere. Different from the rapid response of the deep branch of the BDC, tropical upwelling in the lower stratosphere accelerates up to 20%–40% compared with the climatology, 20–30 days after the onset of the SSWs,and the acceleration lasts for one to three months. The enhancement of tropical upwelling is associated with the large-scale wave-breaking in the subtropics interacting with the midlatitude and tropical Quasi-Biennial Oscillation–related mean flow. 展开更多
关键词 sudden stratospheric major warming Brewer–Dobson circulation subtropical wave
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