Xishui National Forest Park in Heilongjiang Province hosts China's most pristine temperate forests and serves as a key site for ecotourism and forest therapy.However,the emission patterns of phytoncides(key bio ac...Xishui National Forest Park in Heilongjiang Province hosts China's most pristine temperate forests and serves as a key site for ecotourism and forest therapy.However,the emission patterns of phytoncides(key bio active compounds) remain poorly understood,limiting their therapeutic application.This study provides the first comprehensive characterization of spatiotemporal dynamics in airborne phytoncides and their synergistic interactions with environmental factors throughout the autumn-early spring seasonal transition in a temperate forest ecosystem.We analyzed the compositional dynamics of phytoncides and terpenoid content variations using thermal desorption-gas chromatography-mass spectrometry(TD-GC-MS) from September 2024 to March 2025.This period encompassed seasonal transitions from autumn to early spring,including diurnal variations in September and snowfall events in November.The method demonstrated detection limits(LODs) ranging from 1.35 to 5.33 ng m-3 and quantification limits(LOQs) from 4.09 to 16.15 ng m-3.Our results revealed pronounced seasonal fluctuations in phytoncide composition.In September,terpenoids,esters,alcohols,and alkanes displayed a diurnal "decrease-increase" trend,whereas aldehydes and ketones peaked at midday.Notably,esters and alcohols were undetectable in November and January.By January,terpenoids reached their lowest proportion(0.17±0.02%) at noon.Five terpenoids(α-pinene,myrcene,D-limonene,camphene,p-cymene) were detected in September,four(α-pinene,D-limonene,camphene,p-cymene) in November,two(D-limonene,p-cymene) in January,and only p-cymene in March.The total concentration and emission rate of the five terpenoids peaked in September afternoons at 1961.58±106.67 ng m^(-3) and653.86±35.56 ng m^(-3) h^(-1),respectively.Nocturnal emissions(32131.95±2522.21 ng m^(-3)) significantly surpassed daytime levels(14473.04±958.49 ng m^(-3)),with emission rates escalating from 1447.30±95.85 ng m^(-3) h^(-1)(day) to 5355.33±420.37 ng m^(-3) h^(-1)(night),marking a3.7-fold increase.Snowfall dramatically elevated terpenoid concentrations(pre-snowfall:158.58±14.12 ng m^(-3);post-snowfall:1080.57±57.76 ng m^(-3)) and emission rates(pre-snowfall:52.86±4.71 ng m^(-3) h^(-1);post-snowfall:360.19±19.25 ng m^(-3) h^(-1)),reflecting a 6.8-fold surge.This study underscores the profound influence of light intensity,seasonal shifts,and climatic conditions on airborne phytoncide levels,offering a scientific foundation for optimizing forest therapy and ecotourism strategies.展开更多
Dynamic melt modification of polyethylene via the direct grafting of peroxide fragments shows promise for the development of processable functionalized materials.In this study,four linear low-density polyethylenes(LLD...Dynamic melt modification of polyethylene via the direct grafting of peroxide fragments shows promise for the development of processable functionalized materials.In this study,four linear low-density polyethylenes(LLDPEs)with comparable molecular weights but different short-chain branch(SCB)contents(ranging of 5-66 per 1000 carbon atoms)were modified via dynamic melt mixing using 2 wt% benzoyl peroxide at 145℃ and 50 r/min for 30 min.The influence of SCB content on the processability and structure of the resulting products was systematically investigated.All modified products exhibited good melt processability with melt flow rates(MFR)ranging from 0.46 g/10min to 1.07 g/10min.Products derived from low-SCB LLDPEs showed a lower MFR,higher cross-linking content,a larger number of long-chain branches,and a higher degree of benzoyl grafting.In contrast,those produced from high-SCB LLDPEs exhibited improved processability,reduced cross-linking,fewer long-chain branches,and lower benzoyl grafting levels.A detailed structural investigation of the soluble and insoluble fractions,which were separated using trichlorobenzene fractionation,was conducted to analyze the structural features of various modified products and demonstrate that the SCB content(i.e.,tertiary carbon density)significantly influences radical coupling during dynamic modification.Elevated tertiary carbon density,by introducing greater steric hindrance,suppresses radical coupling during dynamic modification,thereby reducing the efficiency of both crosslinking and peroxide fragment grafting.These findings provide new insights into the structure-reactivity relationships in peroxide-induced polyethylene modification and lay the foundation for tailoring material properties via dynamic processing.展开更多
Optimizing plant architecture for specific cultivation methods is essential for enhancing fruit productivity.Unlike indeterminate growth plants,the total productivity of determinate growth plants relies on cumulative ...Optimizing plant architecture for specific cultivation methods is essential for enhancing fruit productivity.Unlike indeterminate growth plants,the total productivity of determinate growth plants relies on cumulative fruit production and synchronized fruit ripening from both main and axillary shoots.Here,we focused on SlD14and SlMAX1,two key genes involved in the regulation of strigolactone(SL)signaling and biosynthesis,with the goal of maximizing yield and syn chronizing fruit ripening by fine-tuning axillary shoot growth.Using clustered regularly interspaced short palindromic repeats(CRISPR)/CRISPR-associated protein 9(Cas9)technology,we found that the sld14,slmax1,and sld14 slmax1mutant plants exhibited reduced plant height and increased axillary shoot proliferation compared to wild-type plants.However,these mutants showed reduced yield and delayed ripening,likely due to a source-sink imbalance caused by excessive axillary shoot development.A weak sld14 allele displayed a milder phenotype,maintaining total fruit yield and harvest index despite smaller individual fruit size.These findings indicate that allelic variation in SL-related genes can influence plant architecture and yield components.Our results suggest that weak or partial alleles may serve as promising targets for tailoring tomato architecture to space-limited cultivation systems.展开更多
Urban forests are essential components of green infrastructure,however,rapid urbanization-induced changes in landscape patterns may affect their ecosystem services through complex ecological processes.A total of 184 s...Urban forests are essential components of green infrastructure,however,rapid urbanization-induced changes in landscape patterns may affect their ecosystem services through complex ecological processes.A total of 184 sample plots in the built-up areas of Nanchang,China,were used as research sites.Urbanization intensities were categorized by the rate of impervious surface area,and forest types were classified into landscape and relaxation forest,attached forest(AF),road forest(RF),and ecological public welfare forest.This study aimed to explore the spatial variations in vegetation characteristics and landscape pattern indices of different forest types under rapid urbanization.The results indicated that the largest patch index(LPI),aggregation index(AI),and percentage of landscape(PLAND)in RF and AF were lower than those in the other forest types(p<0.05).With increasing urbanization intensity,the mean perimeter-area ratio increased by 130.84%,whereas the PLAND,LPI,and AI decreased by 22−86%(p<0.05).Redundancy analysis and variation partitioning suggested that the interpretation rate of landscape pattern indices for variations in vegetation characteristics increased from low to heavy urbanization areas.Especially,the landscape shape index,patch connection index,PLAND,and mean patch size were significantly correlated with vegetation characteristics(e.g.,tree richness,herb coverage,and tree height).In the future,appropriate landscape layout superiority cases should be considered in different urbanization areas and forest types;for instance,increasing the patch connection index will beneficially improve the diversity of trees and herbs in heavy urbanization areas and the RF.This study serves as a reference for maximizing the ecosystem services of urban forests.展开更多
The performance of data restore is one of the key indicators of user experience for backup storage systems.Compared to the traditional offline restore process,online restore reduces downtime during backup restoration,...The performance of data restore is one of the key indicators of user experience for backup storage systems.Compared to the traditional offline restore process,online restore reduces downtime during backup restoration,allowing users to operate on already restored files while other files are still being restored.This approach improves availability during restoration tasks but suffers from a critical limitation:inconsistencies between the access sequence and the restore sequence.In many cases,the file a user needs to access at a given moment may not yet be restored,resulting in significant delays and poor user experience.To this end,we present Histore,which builds on the user’s historical access sequence to schedule the restore sequence,in order to reduce users’access delayed time.Histore includes three restore approaches:(i)the frequency-based approach,which restores files based on historical file access frequencies and prioritizes ensuring the availability of frequently accessed files;(ii)the graph-based approach,which preferentially restores the frequently accessed files as well as their correlated files based on historical access patterns,and(iii)the trie-based approach,which restores particular files based on both users’real-time and historical access patterns to deduce and restore the files to be accessed in the near future.We implement a prototype of Histore and evaluate its performance from multiple perspectives.Trace-driven experiments on two datasets show that Histore significantly reduces users’delay time by 4-700×with only 1.0%-14.5%additional performance overhead.展开更多
Tajikistan represents a core region of the biodiversity hotspot in Central Asian mountains and has exceptional vascular plant diversity.However,the species diversity of the country faces urgent conservation challenges...Tajikistan represents a core region of the biodiversity hotspot in Central Asian mountains and has exceptional vascular plant diversity.However,the species diversity of the country faces urgent conservation challenges.There has been a lack of a comprehensive and multidimensional assessment to inform strategic conservation planning.Therefore,this study integrated 4 key biodiversity indices including species richness(SR),phylogenetic diversity(PD),threatened species richness(TSR),and endemic species richness(ESR)to map species diversity distribution patterns,identify conservation gaps,and elucidate their effects of climatic factors.This study revealed that species diversity shows a clear trend of decreasing from the western region to the eastern region of Tajikistan.The central–western mountains(specifically the Gissar-Darvasian and Zeravshanian regions)emerge as irreplaceable biodiversity hotspots.However,we found a severe spatial mismatch between these priority areas and the existing protected areas(PAs).Protection coverage for all hotspots was alarmingly low,ranging from 31.00%to 38.00%.Consequently,a critical 64.80%of integrated priority areas fall outside of the current PAs,representing a major conservation gap.This study identified precipitation seasonality and isothermality as the principal drivers,collectively explaining over 50.00%of the diversity variation and suggesting high vulnerability to hydrological shifts.Furthermore,we detected significant geographic sampling bias in the public biodiversity databases,with the most critical hotspot being systematically under-sampled.This study provides a robust scientific basis for conservation action,highlighting the urgent need to strategically expand PAs in the under-protected southwestern region and to mitigate critical sampling gaps through targeted data digitization and field surveys.These measures are indispensable for securing Tajikistan’s unique biodiversity and achieving the Kunming-Montreal Global Biodiversity Framework Target 3(“30×30 Protection”).展开更多
Wide-field mesoscopy provides the capabilities of cortex-wide field of view(FOV),cellular resolution and high frame rate for neuronal imaging in the mouse brain.However,inherent background fluorescence degrades the im...Wide-field mesoscopy provides the capabilities of cortex-wide field of view(FOV),cellular resolution and high frame rate for neuronal imaging in the mouse brain.However,inherent background fluorescence degrades the image quality and hinders neuronal signal extraction.To address this problem,we first introduce a cortex-wide,high-resolution lineillumination mesoscope with a moving slit designed for in vivo mouse brain imaging.This system achieves a 6.6×6.6 mm FOV,microscale cellular resolution,a high frame rate of 10 Hz,as well as the background rejection ability.Furthermore,we integrated patterned illumination into the system to enhance the background suppression.Experimental results show that the proposed system successfully captures neurodynamics in the living mouse brain.Compared with conventional wide-field mesoscopes,the cortex-wide patterned line-illumination mesoscope(PLIM)achieves a threefold increase in the signal-to-background ratio(SBR).With patterned illumination integrated,the SBR enhancement further reaches four-anda-half-fold.展开更多
BACKGROUND Drug utilization research has an important role in assisting the healthcare administration to know,compute,and refine the prescription whose principal objective is to enable the rational use of drugs.Resear...BACKGROUND Drug utilization research has an important role in assisting the healthcare administration to know,compute,and refine the prescription whose principal objective is to enable the rational use of drugs.Research in developing nations relating to the cost of treatment is scarce when compared with developed countries.Thus,the drug utilization research studies from developing nations are most needed,and their number has been growing.AIM To evaluate patterns of utilization of antipsychotic drugs and direct medical cost analysis in patients newly diagnosed with schizophrenia.METHODS The present study was observational in type and based on a retrospective cohort to evaluate patterns of utilization of antipsychotic drugs using World Health Organization(WHO)core prescribing indicators and anatomical therapeutic chemical/defined daily dose indicators.We also calculated direct medical costs for a period of 6 months.RESULTS This study has found that atypical antipsychotics are the mainstay of treatment for schizophrenia in every age group and subcategories of schizophrenia.The evaluation based on WHO prescribing indicators showed a low average number of drugs per prescription and low prescribing frequency of antipsychotics from the National List of Essential Medicines 2015 and the WHO Essential Medicines List 2019.The total mean drug cost of our study was 1396 Indian rupees.The total mean cost due to the investigation in our study was 1017.34 Indian rupees.Therefore,the total mean direct medical cost incurred on patients in our study was 4337.28 Indian rupees.CONCLUSION The information from the present study can be used for reviewing and updating treatment policy at the institutional level.展开更多
Understanding spatial patterns of plant species diversity and the factors(e.g.,climate and human)that drive these patterns is essential for biodiversity conservation.We used data from 1700.1-ha forest plots in the She...Understanding spatial patterns of plant species diversity and the factors(e.g.,climate and human)that drive these patterns is essential for biodiversity conservation.We used data from 1700.1-ha forest plots in the Shettihalli tropical forest landscape of the Western Ghats biodiversity hotspot,India,to analyse tree community composition and the drivers ofα-diversity(Shannon)andβ-diversity(LCBD).Compositional patterns were visualized using Non-Metric Multidimensional Scaling(NMDS),and hybrid feature selection with structural equation modeling(SEM)was employed to evaluate the direct and indirect effects of environmental variables on diversity.NMDS identified four distinct forest types in the Shettihalli landscape:semi-evergreen,dry deciduous,moist deciduous,and plantation forests,each with distinct plant composition.Shannon diversity and ecological uniqueness was significantly higher in semi-evergreen forest than in deciduous forest plots.The SEMs explained about 79%and 39–45%of the variation inα-diversity andβ-diversity.Our analysis indicated that current diversity patterns result from multiple processes,with structure,disturbance,and edaphic parameters exerting the strongest direct and indirect effects onα-diversity.β-diversity,in contrast,was largely influenced by climate,topography,stand structure,and edaphic factors.Overall,our findings indicate that various factors(e.g.,climate,topography,and human disturbance)interact to shape tree diversity patterns in tropical forests.These findings will help develop unique conservation and management strategies for distinct forest types in tropical forest ecosystems.展开更多
Mineral resources in Asia continent and its mining industry play a significant role in the economic growth and industrialization of both Asia and the world.Asia continent boasts the most comprehensive kinds of mineral...Mineral resources in Asia continent and its mining industry play a significant role in the economic growth and industrialization of both Asia and the world.Asia continent boasts the most comprehensive kinds of minerals,with reserves of at least 38 of over 80 widely used minerals worldwide accounting for more than30%of the global total reserves.Asia continent experienced three main tectonic evolution and mineralization stages:The Precambrian,the Paleozoic,and the Mesozoic to Cenozoic.The abundant mineral resources in this continent can be divided into seven first-order metallogenic belts(metallogenic domains),18 second-order metallogenic belts(metallogenic provinces),61 third-order metallogenic belts(metallogenic zones),and nine main minerogenetic series.Asia continent exhibits the most significant metallogenic specialization among all continents.Specifically,granite belts of Asia continent manifest pronounced metallogenic specialization of tin,rare metals,and porphyry Cu-Au-Mo deposits.Its maficultramafic rock belts and ophiolite belts display notable metallogenic specialization of lateritic nickel deposits and magmatic type chromite deposits,while its Mesozoic to Cenozoic basalt belts show remarkable metallogenic specialization of lateritic bauxite deposits.Consequently,many giant metallogenic belts were formed,including the Southeast Asian tin belt,the Qinghai-Xizang Plateau rare metal metallogenic belt,the Tethyan porphyry Cu-Au-Mo metallogenic belt,the circum-Pacific porphyry Cu-Au-Mo metallogenic belt,the Southeast Asian lateritic bauxite metallogenic belt,the Deccan Plateau lateritic bauxite metallogenic belt in India,the Southeast Asian lateritic nickel metallogenic belt,and the Tethyan magmatic type chromite metallogenic belt—all of which are significant metallogenic belts in Asia continent.Future mineral exploration in Asia should focus primarily on the Precambrian mineralization of ancient cratons,the Paleozoic mineralization of the Central Asian-Mongolian orogenic belt,and the Mesozoic to Cenozoic mineralization of the Tethyan and circum-Pacific mobile belts.Asia's mining industry not only underpins its own economic growth but also propels global economic development and industrialization,contributing significantly to the world economy.Asia boasts the highest production value of minerals,the largest annual production of minerals,and the greatest trade value of mineral products among all the continents,having emerged as the trade center of global mineral products and the center of the mining industry economy.China is identified as one of the few countries that possess the most comprehensive kinds of minerals,and its mining industry has supported and driven the economic development and industrialization of Asia and even the world.Standing as the largest mineral producer worldwide,China ranked first in the production of 28 mineral commodities in the world in 2022.Besides,China exhibits the highest annual production value of minerals and the largest trade value of mineral products among all countries.Therefore,China's demand for global mineral products influences the global supply and demand patterns of minerals and the world economic situation.展开更多
Dendritic branching patterns at variable cross-sections in Ni-based single crystal(SX) castings of different generations were investigated using optical microscope(OM), electro probe microanalyzer(EPMA),differential s...Dendritic branching patterns at variable cross-sections in Ni-based single crystal(SX) castings of different generations were investigated using optical microscope(OM), electro probe microanalyzer(EPMA),differential scanning calorimeter(DSC), Thermo-Cal software and Pro-CAST software. Results show that the dendritic branching patterns are similar in outward platform in SXs of different generations. That is, the primary dendrites(PDs) are introduced into the platform by developing a series of secondary dendrites(SDs) to occupy the bottom of the platform, and the ternary dendrites(TDs) originating from these SDs grow upward to fill up the platform. With the SX generation increasing, the undercooling of melts in the inward platform increases significantly due to the increasing alloying elements and the segregation in the directional solidification(DS)process, and the growth velocity of the dendrite tip increases according to the dynamic model of dendrite growth,which is beneficial for the high-order dendrite development. The stronger dendritic branching ability is shown in the inward platform of the higher generation Ni-based SX.展开更多
To the Editor: There are still some open issues about the systematization of the knowledge of the branching of the left portal vein(LPV) and the division in anatomo-functional units within the left liver. The first co...To the Editor: There are still some open issues about the systematization of the knowledge of the branching of the left portal vein(LPV) and the division in anatomo-functional units within the left liver. The first controversial topic concerns the division of S4 in subsegments. The Brisbane 20 0 0 system of Nomenclature of Hepatic Anatomy and Resections(B20 0 0) [1] does not mention such subdivision, but in literature this is still a matter of discussion.展开更多
Plant height(PH),primary lateral branch length(PBL),and branch number(BN)are architectural components impacting peanut pod yield,biomass production,and adaptivity to mechanical harvesting.In this study,a recombinant i...Plant height(PH),primary lateral branch length(PBL),and branch number(BN)are architectural components impacting peanut pod yield,biomass production,and adaptivity to mechanical harvesting.In this study,a recombinant inbred population consisting of 181 individual lines was used to determine genetic controls of PH,PBL,and BN across three environments.Phenotypic data collected from the population demonstrated continuous distributions and transgressive segregation patterns.Broad-sense heritability of PH,PBL,and BN was found to be 0.87,0.88,and 0.92,respectively.Unconditional individual environmental analysis revealed 35 additive QTLs with phenotypic variation explained(PVE)ranging from 4.57 to 21.68%.A two-round meta-analysis resulted in 24consensus and 19 unique QTLs.Five unique QTLs exhibited pleiotropic effects and their genetic bases(pleiotropy or tight linkage)were evaluated.A joint analysis was performed to estimate the QTL by environment interaction(QEI)effects on PH,PBL,and BN,collectively explaining phenotypic variations of 10.80,11.02,and 7.89%,respectively.We identified 3 major and stable QTL regions(uq9-3,uq10-2,and uq16-1)on chromosomes 9,10,and 16,spanning1.43-1.53 Mb genomic regions.Candidate genes involved in phytohormones biosynthesis,signaling,and cell wall development were proposed to regulate these morphological traits.These results provide valuable information for further genetic studies and the development of molecular markers applicable to peanut architecture improvement.展开更多
Branching is a critical aspect of plant architecture that significantly impacts the yield and adaptability of staple cereal crops like rice and wheat.Cereal crops develop tillers during the vegetative stage and panicl...Branching is a critical aspect of plant architecture that significantly impacts the yield and adaptability of staple cereal crops like rice and wheat.Cereal crops develop tillers during the vegetative stage and panicle or spike branches during the reproductive stage,respectively,both of which are significantly impacted by hormones and genetic factors.Tillering and panicle branching are closely interconnected and exhibit high environmental plasticity.Here,we summarize the recent progress in genetic,hormonal,and environmental factors regulation in the branching of rice and wheat.This review not only provides a comprehensive overview of the current knowledge on branching mechanisms in rice and wheat,but also explores the prospects for future research aimed at optimizing crop architecture for enhanced productivity.展开更多
The preparation of red,green,and blue quantum dot(QD)pixelated arrays with high precision,resolution,and brightness poses a significant challenge on the development of advanced micro-displays for virtual,augmented,and...The preparation of red,green,and blue quantum dot(QD)pixelated arrays with high precision,resolution,and brightness poses a significant challenge on the development of advanced micro-displays for virtual,augmented,and mixed reality applications.Alongside the controlled synthesis of high-performance QDs,a reliable QD patterning technology is crucial in overcoming this challenge.Among the various methods available,photolithography-based patterning technologies show great potentials in producing ultra-fine QD patterns at micron scale.This review article presents the recent advancements in the field of QD patterning using photolithography techniques and explores their applications in micro-display technology.Firstly,we discuss QD patterning through photolithography techniques employing photoresist(PR),which falls into two categories:PRassisted photolithography and photolithography of QDPR.Subsequently,direct photolithography techniques based on photo-induced crosslinking of photosensitive groups and photo-induced ligand cleavage mechanisms are thoroughly reviewed.Meanwhile,we assess the performance of QD arrays fabricated using these photolithography techniques and their integration into QD light emitting diode display devices as well as color conversionbased micro light emitting diode display devices.Lastly,we summarize the most recent developments in this field and outline future prospects.展开更多
Ecological security provides the basis of maintaining both a sustainable regional ecosystem and economic development.However,few studies have focused on how the features such as topography and geomorphology,lithologic...Ecological security provides the basis of maintaining both a sustainable regional ecosystem and economic development.However,few studies have focused on how the features such as topography and geomorphology,lithologic stratigraphic assemblages,and geohazard distribution affect the construction of ecological security patterns and the layout of optimization measures.In order to comprehensively reveal the key areas and key objects of ecological restoration in karst basins,this study takes the Beipan River Basin(BRB)as an example,constructs an ecological security pattern(ESP)based on the methods of morphological spatial pattern analysis(MSPA),landscape connectivity analysis and circuit theory,and lays out the optimization measures in combination with the spatial distribution characteristics of topographic and geomorphological differences and lithological stratigraphic combinations.The results show that 151 ecological sources,343 ecological corridors,121 pinch points and 178 barriers constitute the ESP of the BRB.Lithology is closely related to the spatial distribution characteristics of ecological source sites.Level 1 and 2 ecological sources(The ecological sources were categorized into level 1,level 2,and level 3 source from high to low importance.)are concentrated in the Emeishan basalt region of the upstream and the clastic and impure carbonate rock region of the downstream part of the BRB;level 3ecological sources are concentrated in the carbonate rock region of the midstream.Taking into account the outstanding ecological problems in the basin,and based on the characteristics of lithology and geohazard distribution,we propose the optimization scheme of“three axes,three zones and multiple points”for the ESP and the layout of specific measures of the BRB.The results can provide scientific references for maintaining ecological security maintenance in karst ecologically fragile areas.展开更多
The Hengduan Mountains,situated on the southeastern edge of the Qinghai-Tibet Plateau,are the longest and widest north-south-oriented mountain range in China,exerting a significant influence on the ecological and geog...The Hengduan Mountains,situated on the southeastern edge of the Qinghai-Tibet Plateau,are the longest and widest north-south-oriented mountain range in China,exerting a significant influence on the ecological and geographical pattern.Understanding the topographic and geomorphological characteristics of the Hengduan Mountains is fundamental and crucial for research in related fields such as ecology,geography,and sustainability.In this study,Digital Elevation Model(DEM)data were utilized to extract and analyze the topography and geomorphology(TG)pattern.TG maps have been developed to quantitatively classify the TG types in the Hengduan Mountains by combining the five factors of elevation,slope,aspect,relief and landform.The spatial distribution and quantitative characteristics of these factors were mapped and investigated using geographic information systems.The results revealed that:(1)The Hengduan Mountains exhibit an elongated north-south distribution,with an average elevation of approximately 3746 m,an average slope of around 25°,and an average relief of about 266 m.(2)The Hengduan Mountains display significant elevation differences,with an overall high elevation,characterized by a trend of lower elevation in the east and higher elevation in the west,as well as irregular orientations of various aspects.(3)The 19 landform types were identified,the landform types of the Hengduan Mountains are primarily composed of low-relief high-mountains(42.0618%),low-relief mid-mountains(22.4624%),and high-elevation hills(20.5839%).The results of the study can provide data and information support for the ecology,environmental protection and sustainable development of the Hengduan Mountains.展开更多
AIM:To report the demographic and systemic characteristics of patients,clinical progression of endophthalmitis,and the efficacy of various treatment strategies,with a focus on identifying key factors for preserving vi...AIM:To report the demographic and systemic characteristics of patients,clinical progression of endophthalmitis,and the efficacy of various treatment strategies,with a focus on identifying key factors for preserving vision in eyes with endogenous endophthalmitis due to Klebsiella pneumoniae(K.pneumoniae)liver abscess.METHODS:In this single-center,retrospective case series of 18 patients with endogenous endophthalmitis due to K.pneumoniae liver abscess were analyzed.Ophthalmologic features of endophthalmitis at early,intermediate and advanced stages were obtained from eyes with endophthalmitis of different severities.Prompt vitrectomy was considered primarily for all eyes except for very early endophthalmitis.Intravitreal injections of antibiotics were performed in eyes with endophthalmitis in the very early stages and in eyes where vitrectomy was not available,and additional control of infection was needed after vitrectomy.Evisceration was performed in eyes with corneoscleral perforation,advanced endophthalmitis,perforation with preseptal or orbital cellulitis,uncontrolled infection,or severe pain with no vision.RESULTS:Mean(±standard deviation)age of the 18 patients with endophthalmitis was 64.5±12.2(range:32-84)y,and 14 patients(77.8%)were males.Endophthalmitis tended to involve the retinal parenchyma first and then progressed into the vitreous cavity and anterior segments.However,it presented a tendency to cause massive subretinal abscesses even after vitrectomy with silicone oil tamponade.Very high intraocular pressure with new vessels on the iris(41.7%)were also commonly observed.Although all but three patients had systemic disease such as diabetes or hypertension,visual prognosis after treatment did not appear to depend significantly on underlying comorbidities.A final best-corrected visual acuity better than 20/60 was achieved only when lesions were detected very early,with relatively good initial visual acuity,likely reflecting lower bacterial inoculation in the eye.CONCLUSION:Detection of early endophthalmitis lesions appears to be the only way to preserve good vision in patients with K.pneumoniae liver abscesses.Therefore,proper guidelines for ophthalmologic screening remain to be established for subjects at a high risk of endophthalmitis.展开更多
Clarifying the mechanisms that control the evolution of territorial space patterns is essential for regulating and optimizing the geographical structure and processes related to sustainable development.Using the Guang...Clarifying the mechanisms that control the evolution of territorial space patterns is essential for regulating and optimizing the geographical structure and processes related to sustainable development.Using the Guangdong and Guangxi sections of the Pearl River Basin as examples,the transfer-matrix method and standard deviation ellipse model were applied to characterize the evolution of territorial space patterns from 1990 to 2020.A trend surface analysis and the Theil index were used to analyze regional differences in the evolution process,and geodetectors were used to identify the underlying mechanisms of the changes.There were three key results.(1)In these critical areas of the Pearl River Basin,agricultural and ecological spaces have rapidly declined due to urban expansion,with transfers between these spaces dominating the evolution of territorial space patterns.Spatial pattern changes in the Guangdong section were more intense than in the Guangxi section.(2)Regional differences in urban space have decreased,whereas differences in agricultural and ecological spaces have intensified.Driven by socio-economic growth,the cross-regional transfers of territorial space have created a“high in the east,while low in the west”inter-regional difference,and a“high in the south,while low in the north”intra-regional difference shaped by natural conditions.The regional differences in space patterns were greater in Guangdong than in Guangxi.(3)The evolution of watershed territorial space patterns resulted from scale changes,locational shifts,structural reorganizations,and directional changes driven by multiple factors.Natural environment,social life,economic development,and policy factors played foundational,leading,key driving,and guiding roles,respectively.Additionally,the regional differences in the evolution of watershed territorial space patterns originated from the differential transmission of the influence of various factors affecting spatial evolution.Enhancing urban space efficiency,restructuring agricultural space,and optimizing ecological space are key strategies for building a complementary and synergistic territorial space pattern in the basin.展开更多
基金supported by the Key Research and Development Plan Project of Heilongjiang Province (2022ZX02C13)。
文摘Xishui National Forest Park in Heilongjiang Province hosts China's most pristine temperate forests and serves as a key site for ecotourism and forest therapy.However,the emission patterns of phytoncides(key bio active compounds) remain poorly understood,limiting their therapeutic application.This study provides the first comprehensive characterization of spatiotemporal dynamics in airborne phytoncides and their synergistic interactions with environmental factors throughout the autumn-early spring seasonal transition in a temperate forest ecosystem.We analyzed the compositional dynamics of phytoncides and terpenoid content variations using thermal desorption-gas chromatography-mass spectrometry(TD-GC-MS) from September 2024 to March 2025.This period encompassed seasonal transitions from autumn to early spring,including diurnal variations in September and snowfall events in November.The method demonstrated detection limits(LODs) ranging from 1.35 to 5.33 ng m-3 and quantification limits(LOQs) from 4.09 to 16.15 ng m-3.Our results revealed pronounced seasonal fluctuations in phytoncide composition.In September,terpenoids,esters,alcohols,and alkanes displayed a diurnal "decrease-increase" trend,whereas aldehydes and ketones peaked at midday.Notably,esters and alcohols were undetectable in November and January.By January,terpenoids reached their lowest proportion(0.17±0.02%) at noon.Five terpenoids(α-pinene,myrcene,D-limonene,camphene,p-cymene) were detected in September,four(α-pinene,D-limonene,camphene,p-cymene) in November,two(D-limonene,p-cymene) in January,and only p-cymene in March.The total concentration and emission rate of the five terpenoids peaked in September afternoons at 1961.58±106.67 ng m^(-3) and653.86±35.56 ng m^(-3) h^(-1),respectively.Nocturnal emissions(32131.95±2522.21 ng m^(-3)) significantly surpassed daytime levels(14473.04±958.49 ng m^(-3)),with emission rates escalating from 1447.30±95.85 ng m^(-3) h^(-1)(day) to 5355.33±420.37 ng m^(-3) h^(-1)(night),marking a3.7-fold increase.Snowfall dramatically elevated terpenoid concentrations(pre-snowfall:158.58±14.12 ng m^(-3);post-snowfall:1080.57±57.76 ng m^(-3)) and emission rates(pre-snowfall:52.86±4.71 ng m^(-3) h^(-1);post-snowfall:360.19±19.25 ng m^(-3) h^(-1)),reflecting a 6.8-fold surge.This study underscores the profound influence of light intensity,seasonal shifts,and climatic conditions on airborne phytoncide levels,offering a scientific foundation for optimizing forest therapy and ecotourism strategies.
基金financially supported by the Science and Technology Project of PetroChina Company Limited,China(No.2022DJ6314)the National Natural Science Foundation of China(No.52173056)。
文摘Dynamic melt modification of polyethylene via the direct grafting of peroxide fragments shows promise for the development of processable functionalized materials.In this study,four linear low-density polyethylenes(LLDPEs)with comparable molecular weights but different short-chain branch(SCB)contents(ranging of 5-66 per 1000 carbon atoms)were modified via dynamic melt mixing using 2 wt% benzoyl peroxide at 145℃ and 50 r/min for 30 min.The influence of SCB content on the processability and structure of the resulting products was systematically investigated.All modified products exhibited good melt processability with melt flow rates(MFR)ranging from 0.46 g/10min to 1.07 g/10min.Products derived from low-SCB LLDPEs showed a lower MFR,higher cross-linking content,a larger number of long-chain branches,and a higher degree of benzoyl grafting.In contrast,those produced from high-SCB LLDPEs exhibited improved processability,reduced cross-linking,fewer long-chain branches,and lower benzoyl grafting levels.A detailed structural investigation of the soluble and insoluble fractions,which were separated using trichlorobenzene fractionation,was conducted to analyze the structural features of various modified products and demonstrate that the SCB content(i.e.,tertiary carbon density)significantly influences radical coupling during dynamic modification.Elevated tertiary carbon density,by introducing greater steric hindrance,suppresses radical coupling during dynamic modification,thereby reducing the efficiency of both crosslinking and peroxide fragment grafting.These findings provide new insights into the structure-reactivity relationships in peroxide-induced polyethylene modification and lay the foundation for tailoring material properties via dynamic processing.
基金funded by the National Research Foundation of Korea(NRF)grant from the Ministry of Science and ICT(MSIT),Republic of Korea(Nos.RS-2024-00407469 and RS-2025-00517964)the BK21 FOUR program of Graduate School,Kyung Hee University(GS-1-JO-NON-20240417)。
文摘Optimizing plant architecture for specific cultivation methods is essential for enhancing fruit productivity.Unlike indeterminate growth plants,the total productivity of determinate growth plants relies on cumulative fruit production and synchronized fruit ripening from both main and axillary shoots.Here,we focused on SlD14and SlMAX1,two key genes involved in the regulation of strigolactone(SL)signaling and biosynthesis,with the goal of maximizing yield and syn chronizing fruit ripening by fine-tuning axillary shoot growth.Using clustered regularly interspaced short palindromic repeats(CRISPR)/CRISPR-associated protein 9(Cas9)technology,we found that the sld14,slmax1,and sld14 slmax1mutant plants exhibited reduced plant height and increased axillary shoot proliferation compared to wild-type plants.However,these mutants showed reduced yield and delayed ripening,likely due to a source-sink imbalance caused by excessive axillary shoot development.A weak sld14 allele displayed a milder phenotype,maintaining total fruit yield and harvest index despite smaller individual fruit size.These findings indicate that allelic variation in SL-related genes can influence plant architecture and yield components.Our results suggest that weak or partial alleles may serve as promising targets for tailoring tomato architecture to space-limited cultivation systems.
基金supported by the National Natural Science Foundation of China(32460380,42007042)State Key Laboratory of Subtropical Silviculture(SKLSSKF2023-06)+2 种基金Natural Science Foundation of Jiangxi Province(20242BAB25389)National Undergraduate Innovation and Entrepreneurship Training Program(202410410029X)Jiangxi Province Graduate Student Innovation Special Fund Project(YC2024-S330).
文摘Urban forests are essential components of green infrastructure,however,rapid urbanization-induced changes in landscape patterns may affect their ecosystem services through complex ecological processes.A total of 184 sample plots in the built-up areas of Nanchang,China,were used as research sites.Urbanization intensities were categorized by the rate of impervious surface area,and forest types were classified into landscape and relaxation forest,attached forest(AF),road forest(RF),and ecological public welfare forest.This study aimed to explore the spatial variations in vegetation characteristics and landscape pattern indices of different forest types under rapid urbanization.The results indicated that the largest patch index(LPI),aggregation index(AI),and percentage of landscape(PLAND)in RF and AF were lower than those in the other forest types(p<0.05).With increasing urbanization intensity,the mean perimeter-area ratio increased by 130.84%,whereas the PLAND,LPI,and AI decreased by 22−86%(p<0.05).Redundancy analysis and variation partitioning suggested that the interpretation rate of landscape pattern indices for variations in vegetation characteristics increased from low to heavy urbanization areas.Especially,the landscape shape index,patch connection index,PLAND,and mean patch size were significantly correlated with vegetation characteristics(e.g.,tree richness,herb coverage,and tree height).In the future,appropriate landscape layout superiority cases should be considered in different urbanization areas and forest types;for instance,increasing the patch connection index will beneficially improve the diversity of trees and herbs in heavy urbanization areas and the RF.This study serves as a reference for maximizing the ecosystem services of urban forests.
基金supported in part by National Key R&D Program of China(2022YFB4501200),National Natural Science Foundation of China(62332018)Science and Technology Program(2024NSFTD0031,2024YFHZ0339 and 2025ZNSFSC0497).
文摘The performance of data restore is one of the key indicators of user experience for backup storage systems.Compared to the traditional offline restore process,online restore reduces downtime during backup restoration,allowing users to operate on already restored files while other files are still being restored.This approach improves availability during restoration tasks but suffers from a critical limitation:inconsistencies between the access sequence and the restore sequence.In many cases,the file a user needs to access at a given moment may not yet be restored,resulting in significant delays and poor user experience.To this end,we present Histore,which builds on the user’s historical access sequence to schedule the restore sequence,in order to reduce users’access delayed time.Histore includes three restore approaches:(i)the frequency-based approach,which restores files based on historical file access frequencies and prioritizes ensuring the availability of frequently accessed files;(ii)the graph-based approach,which preferentially restores the frequently accessed files as well as their correlated files based on historical access patterns,and(iii)the trie-based approach,which restores particular files based on both users’real-time and historical access patterns to deduce and restore the files to be accessed in the near future.We implement a prototype of Histore and evaluate its performance from multiple perspectives.Trace-driven experiments on two datasets show that Histore significantly reduces users’delay time by 4-700×with only 1.0%-14.5%additional performance overhead.
基金the Chinese Academy of Sciences Research Center for Ecology and Environment of Central Asia(RCEECA),the construction and joint research for the China-Tajikistan“Belt and Road”Joint Laboratory on Biodiversity Conservation and Sustainable Use(2024YFE0214200)the Shanghai Cooperation Organization Partnership and International Technology Cooperation Plan of Science and Technology Projects(2023E01018,2025E01056)the Chinese Academy of Sciences President’s International Fellowship Initiative(PIFI)(2024VBC0006).
文摘Tajikistan represents a core region of the biodiversity hotspot in Central Asian mountains and has exceptional vascular plant diversity.However,the species diversity of the country faces urgent conservation challenges.There has been a lack of a comprehensive and multidimensional assessment to inform strategic conservation planning.Therefore,this study integrated 4 key biodiversity indices including species richness(SR),phylogenetic diversity(PD),threatened species richness(TSR),and endemic species richness(ESR)to map species diversity distribution patterns,identify conservation gaps,and elucidate their effects of climatic factors.This study revealed that species diversity shows a clear trend of decreasing from the western region to the eastern region of Tajikistan.The central–western mountains(specifically the Gissar-Darvasian and Zeravshanian regions)emerge as irreplaceable biodiversity hotspots.However,we found a severe spatial mismatch between these priority areas and the existing protected areas(PAs).Protection coverage for all hotspots was alarmingly low,ranging from 31.00%to 38.00%.Consequently,a critical 64.80%of integrated priority areas fall outside of the current PAs,representing a major conservation gap.This study identified precipitation seasonality and isothermality as the principal drivers,collectively explaining over 50.00%of the diversity variation and suggesting high vulnerability to hydrological shifts.Furthermore,we detected significant geographic sampling bias in the public biodiversity databases,with the most critical hotspot being systematically under-sampled.This study provides a robust scientific basis for conservation action,highlighting the urgent need to strategically expand PAs in the under-protected southwestern region and to mitigate critical sampling gaps through targeted data digitization and field surveys.These measures are indispensable for securing Tajikistan’s unique biodiversity and achieving the Kunming-Montreal Global Biodiversity Framework Target 3(“30×30 Protection”).
基金support from the National Natural Science Foundation of China(Grant No.61971256)。
文摘Wide-field mesoscopy provides the capabilities of cortex-wide field of view(FOV),cellular resolution and high frame rate for neuronal imaging in the mouse brain.However,inherent background fluorescence degrades the image quality and hinders neuronal signal extraction.To address this problem,we first introduce a cortex-wide,high-resolution lineillumination mesoscope with a moving slit designed for in vivo mouse brain imaging.This system achieves a 6.6×6.6 mm FOV,microscale cellular resolution,a high frame rate of 10 Hz,as well as the background rejection ability.Furthermore,we integrated patterned illumination into the system to enhance the background suppression.Experimental results show that the proposed system successfully captures neurodynamics in the living mouse brain.Compared with conventional wide-field mesoscopes,the cortex-wide patterned line-illumination mesoscope(PLIM)achieves a threefold increase in the signal-to-background ratio(SBR).With patterned illumination integrated,the SBR enhancement further reaches four-anda-half-fold.
文摘BACKGROUND Drug utilization research has an important role in assisting the healthcare administration to know,compute,and refine the prescription whose principal objective is to enable the rational use of drugs.Research in developing nations relating to the cost of treatment is scarce when compared with developed countries.Thus,the drug utilization research studies from developing nations are most needed,and their number has been growing.AIM To evaluate patterns of utilization of antipsychotic drugs and direct medical cost analysis in patients newly diagnosed with schizophrenia.METHODS The present study was observational in type and based on a retrospective cohort to evaluate patterns of utilization of antipsychotic drugs using World Health Organization(WHO)core prescribing indicators and anatomical therapeutic chemical/defined daily dose indicators.We also calculated direct medical costs for a period of 6 months.RESULTS This study has found that atypical antipsychotics are the mainstay of treatment for schizophrenia in every age group and subcategories of schizophrenia.The evaluation based on WHO prescribing indicators showed a low average number of drugs per prescription and low prescribing frequency of antipsychotics from the National List of Essential Medicines 2015 and the WHO Essential Medicines List 2019.The total mean drug cost of our study was 1396 Indian rupees.The total mean cost due to the investigation in our study was 1017.34 Indian rupees.Therefore,the total mean direct medical cost incurred on patients in our study was 4337.28 Indian rupees.CONCLUSION The information from the present study can be used for reviewing and updating treatment policy at the institutional level.
基金supported by the Department of Biotechnology,Ministry of Science and Technology,Govt.India,under grant No.BT/Coord.II/10/02/2016/22.03.2018the Indian Council of Social Science Research,New Delhi,India,for providing a short-term doctoral fellowship(RFD/Short-Term/2022-23/ENV/ST/66).
文摘Understanding spatial patterns of plant species diversity and the factors(e.g.,climate and human)that drive these patterns is essential for biodiversity conservation.We used data from 1700.1-ha forest plots in the Shettihalli tropical forest landscape of the Western Ghats biodiversity hotspot,India,to analyse tree community composition and the drivers ofα-diversity(Shannon)andβ-diversity(LCBD).Compositional patterns were visualized using Non-Metric Multidimensional Scaling(NMDS),and hybrid feature selection with structural equation modeling(SEM)was employed to evaluate the direct and indirect effects of environmental variables on diversity.NMDS identified four distinct forest types in the Shettihalli landscape:semi-evergreen,dry deciduous,moist deciduous,and plantation forests,each with distinct plant composition.Shannon diversity and ecological uniqueness was significantly higher in semi-evergreen forest than in deciduous forest plots.The SEMs explained about 79%and 39–45%of the variation inα-diversity andβ-diversity.Our analysis indicated that current diversity patterns result from multiple processes,with structure,disturbance,and edaphic parameters exerting the strongest direct and indirect effects onα-diversity.β-diversity,in contrast,was largely influenced by climate,topography,stand structure,and edaphic factors.Overall,our findings indicate that various factors(e.g.,climate,topography,and human disturbance)interact to shape tree diversity patterns in tropical forests.These findings will help develop unique conservation and management strategies for distinct forest types in tropical forest ecosystems.
基金funded by geological survey project of China Geological Survey(DD20211404)。
文摘Mineral resources in Asia continent and its mining industry play a significant role in the economic growth and industrialization of both Asia and the world.Asia continent boasts the most comprehensive kinds of minerals,with reserves of at least 38 of over 80 widely used minerals worldwide accounting for more than30%of the global total reserves.Asia continent experienced three main tectonic evolution and mineralization stages:The Precambrian,the Paleozoic,and the Mesozoic to Cenozoic.The abundant mineral resources in this continent can be divided into seven first-order metallogenic belts(metallogenic domains),18 second-order metallogenic belts(metallogenic provinces),61 third-order metallogenic belts(metallogenic zones),and nine main minerogenetic series.Asia continent exhibits the most significant metallogenic specialization among all continents.Specifically,granite belts of Asia continent manifest pronounced metallogenic specialization of tin,rare metals,and porphyry Cu-Au-Mo deposits.Its maficultramafic rock belts and ophiolite belts display notable metallogenic specialization of lateritic nickel deposits and magmatic type chromite deposits,while its Mesozoic to Cenozoic basalt belts show remarkable metallogenic specialization of lateritic bauxite deposits.Consequently,many giant metallogenic belts were formed,including the Southeast Asian tin belt,the Qinghai-Xizang Plateau rare metal metallogenic belt,the Tethyan porphyry Cu-Au-Mo metallogenic belt,the circum-Pacific porphyry Cu-Au-Mo metallogenic belt,the Southeast Asian lateritic bauxite metallogenic belt,the Deccan Plateau lateritic bauxite metallogenic belt in India,the Southeast Asian lateritic nickel metallogenic belt,and the Tethyan magmatic type chromite metallogenic belt—all of which are significant metallogenic belts in Asia continent.Future mineral exploration in Asia should focus primarily on the Precambrian mineralization of ancient cratons,the Paleozoic mineralization of the Central Asian-Mongolian orogenic belt,and the Mesozoic to Cenozoic mineralization of the Tethyan and circum-Pacific mobile belts.Asia's mining industry not only underpins its own economic growth but also propels global economic development and industrialization,contributing significantly to the world economy.Asia boasts the highest production value of minerals,the largest annual production of minerals,and the greatest trade value of mineral products among all the continents,having emerged as the trade center of global mineral products and the center of the mining industry economy.China is identified as one of the few countries that possess the most comprehensive kinds of minerals,and its mining industry has supported and driven the economic development and industrialization of Asia and even the world.Standing as the largest mineral producer worldwide,China ranked first in the production of 28 mineral commodities in the world in 2022.Besides,China exhibits the highest annual production value of minerals and the largest trade value of mineral products among all countries.Therefore,China's demand for global mineral products influences the global supply and demand patterns of minerals and the world economic situation.
基金financially supported by the National Key Research and Development Program of China(No.2017YFB0702904)the National Natural Science Foundation of China(No.51631008)
文摘Dendritic branching patterns at variable cross-sections in Ni-based single crystal(SX) castings of different generations were investigated using optical microscope(OM), electro probe microanalyzer(EPMA),differential scanning calorimeter(DSC), Thermo-Cal software and Pro-CAST software. Results show that the dendritic branching patterns are similar in outward platform in SXs of different generations. That is, the primary dendrites(PDs) are introduced into the platform by developing a series of secondary dendrites(SDs) to occupy the bottom of the platform, and the ternary dendrites(TDs) originating from these SDs grow upward to fill up the platform. With the SX generation increasing, the undercooling of melts in the inward platform increases significantly due to the increasing alloying elements and the segregation in the directional solidification(DS)process, and the growth velocity of the dendrite tip increases according to the dynamic model of dendrite growth,which is beneficial for the high-order dendrite development. The stronger dendritic branching ability is shown in the inward platform of the higher generation Ni-based SX.
文摘To the Editor: There are still some open issues about the systematization of the knowledge of the branching of the left portal vein(LPV) and the division in anatomo-functional units within the left liver. The first controversial topic concerns the division of S4 in subsegments. The Brisbane 20 0 0 system of Nomenclature of Hepatic Anatomy and Resections(B20 0 0) [1] does not mention such subdivision, but in literature this is still a matter of discussion.
基金supported by the Natural Science Foundation of Shandong Province,China(ZR2022MC045)the National Natural Science Foundation of China(32001584,32201876)+2 种基金the Major Science and Technology Program of Xinjiang Uygur Autonomous Region,China(2022A02008-3)the Breeding Project from Department of Science&Technology of Shandong Province,China(2022LZGC007)the Agricultural Scientific and the Technological Innovation Project of Shandong Academy of Agricultural Sciences,China(CXGC2023A06,CXGC2023A39 and CXGC2023A46),and the Major Scientific and Technological Achievements Cultivation Program of Shandong Academy of Agricultural Sciences,China(CXGC2025E02)。
文摘Plant height(PH),primary lateral branch length(PBL),and branch number(BN)are architectural components impacting peanut pod yield,biomass production,and adaptivity to mechanical harvesting.In this study,a recombinant inbred population consisting of 181 individual lines was used to determine genetic controls of PH,PBL,and BN across three environments.Phenotypic data collected from the population demonstrated continuous distributions and transgressive segregation patterns.Broad-sense heritability of PH,PBL,and BN was found to be 0.87,0.88,and 0.92,respectively.Unconditional individual environmental analysis revealed 35 additive QTLs with phenotypic variation explained(PVE)ranging from 4.57 to 21.68%.A two-round meta-analysis resulted in 24consensus and 19 unique QTLs.Five unique QTLs exhibited pleiotropic effects and their genetic bases(pleiotropy or tight linkage)were evaluated.A joint analysis was performed to estimate the QTL by environment interaction(QEI)effects on PH,PBL,and BN,collectively explaining phenotypic variations of 10.80,11.02,and 7.89%,respectively.We identified 3 major and stable QTL regions(uq9-3,uq10-2,and uq16-1)on chromosomes 9,10,and 16,spanning1.43-1.53 Mb genomic regions.Candidate genes involved in phytohormones biosynthesis,signaling,and cell wall development were proposed to regulate these morphological traits.These results provide valuable information for further genetic studies and the development of molecular markers applicable to peanut architecture improvement.
基金funded by grants from the National Natural Science Foundation of China (31930006 to Y.W.)the National Key Research and Development Program of China (2022YFF1002903 to Y.W.)+1 种基金the Top Talents Program “One Case One Discussion”(Yishiyiyi to Y.W.)from Shandong provinceShandong Agricultural University Talent Introduction Start-up Fund (to N.Z.)
文摘Branching is a critical aspect of plant architecture that significantly impacts the yield and adaptability of staple cereal crops like rice and wheat.Cereal crops develop tillers during the vegetative stage and panicle or spike branches during the reproductive stage,respectively,both of which are significantly impacted by hormones and genetic factors.Tillering and panicle branching are closely interconnected and exhibit high environmental plasticity.Here,we summarize the recent progress in genetic,hormonal,and environmental factors regulation in the branching of rice and wheat.This review not only provides a comprehensive overview of the current knowledge on branching mechanisms in rice and wheat,but also explores the prospects for future research aimed at optimizing crop architecture for enhanced productivity.
基金supported by the National Natural Science Foundation of China(62374142,12175189 and 11904302)External Cooperation Program of Fujian(2022I0004)+1 种基金Fundamental Research Funds for the Central Universities(20720190005 and 20720220085)Major Science and Technology Project of Xiamen in China(3502Z20191015).
文摘The preparation of red,green,and blue quantum dot(QD)pixelated arrays with high precision,resolution,and brightness poses a significant challenge on the development of advanced micro-displays for virtual,augmented,and mixed reality applications.Alongside the controlled synthesis of high-performance QDs,a reliable QD patterning technology is crucial in overcoming this challenge.Among the various methods available,photolithography-based patterning technologies show great potentials in producing ultra-fine QD patterns at micron scale.This review article presents the recent advancements in the field of QD patterning using photolithography techniques and explores their applications in micro-display technology.Firstly,we discuss QD patterning through photolithography techniques employing photoresist(PR),which falls into two categories:PRassisted photolithography and photolithography of QDPR.Subsequently,direct photolithography techniques based on photo-induced crosslinking of photosensitive groups and photo-induced ligand cleavage mechanisms are thoroughly reviewed.Meanwhile,we assess the performance of QD arrays fabricated using these photolithography techniques and their integration into QD light emitting diode display devices as well as color conversionbased micro light emitting diode display devices.Lastly,we summarize the most recent developments in this field and outline future prospects.
基金jointly supported by the Key Project of the Natural Science Foundation of Guizhou Province(No.Qiankehe Jichu-ZK[2023]Zhongdian027)the Project of the Science and Technology Innovation Base Construction of Guizhou Province(No.Qiankehe Zhongyindi[2023]005)Philosophy and Social Science Planning Subjects in Guizhou Province in 2022(No.22GZYB53)。
文摘Ecological security provides the basis of maintaining both a sustainable regional ecosystem and economic development.However,few studies have focused on how the features such as topography and geomorphology,lithologic stratigraphic assemblages,and geohazard distribution affect the construction of ecological security patterns and the layout of optimization measures.In order to comprehensively reveal the key areas and key objects of ecological restoration in karst basins,this study takes the Beipan River Basin(BRB)as an example,constructs an ecological security pattern(ESP)based on the methods of morphological spatial pattern analysis(MSPA),landscape connectivity analysis and circuit theory,and lays out the optimization measures in combination with the spatial distribution characteristics of topographic and geomorphological differences and lithological stratigraphic combinations.The results show that 151 ecological sources,343 ecological corridors,121 pinch points and 178 barriers constitute the ESP of the BRB.Lithology is closely related to the spatial distribution characteristics of ecological source sites.Level 1 and 2 ecological sources(The ecological sources were categorized into level 1,level 2,and level 3 source from high to low importance.)are concentrated in the Emeishan basalt region of the upstream and the clastic and impure carbonate rock region of the downstream part of the BRB;level 3ecological sources are concentrated in the carbonate rock region of the midstream.Taking into account the outstanding ecological problems in the basin,and based on the characteristics of lithology and geohazard distribution,we propose the optimization scheme of“three axes,three zones and multiple points”for the ESP and the layout of specific measures of the BRB.The results can provide scientific references for maintaining ecological security maintenance in karst ecologically fragile areas.
基金funded by the Yunnan Provincial Basic Research Joint Special Fund Project(2019FH001(-052))Cangshan Mountain Synthetic Scientific Expeditions Fund.
文摘The Hengduan Mountains,situated on the southeastern edge of the Qinghai-Tibet Plateau,are the longest and widest north-south-oriented mountain range in China,exerting a significant influence on the ecological and geographical pattern.Understanding the topographic and geomorphological characteristics of the Hengduan Mountains is fundamental and crucial for research in related fields such as ecology,geography,and sustainability.In this study,Digital Elevation Model(DEM)data were utilized to extract and analyze the topography and geomorphology(TG)pattern.TG maps have been developed to quantitatively classify the TG types in the Hengduan Mountains by combining the five factors of elevation,slope,aspect,relief and landform.The spatial distribution and quantitative characteristics of these factors were mapped and investigated using geographic information systems.The results revealed that:(1)The Hengduan Mountains exhibit an elongated north-south distribution,with an average elevation of approximately 3746 m,an average slope of around 25°,and an average relief of about 266 m.(2)The Hengduan Mountains display significant elevation differences,with an overall high elevation,characterized by a trend of lower elevation in the east and higher elevation in the west,as well as irregular orientations of various aspects.(3)The 19 landform types were identified,the landform types of the Hengduan Mountains are primarily composed of low-relief high-mountains(42.0618%),low-relief mid-mountains(22.4624%),and high-elevation hills(20.5839%).The results of the study can provide data and information support for the ecology,environmental protection and sustainable development of the Hengduan Mountains.
文摘AIM:To report the demographic and systemic characteristics of patients,clinical progression of endophthalmitis,and the efficacy of various treatment strategies,with a focus on identifying key factors for preserving vision in eyes with endogenous endophthalmitis due to Klebsiella pneumoniae(K.pneumoniae)liver abscess.METHODS:In this single-center,retrospective case series of 18 patients with endogenous endophthalmitis due to K.pneumoniae liver abscess were analyzed.Ophthalmologic features of endophthalmitis at early,intermediate and advanced stages were obtained from eyes with endophthalmitis of different severities.Prompt vitrectomy was considered primarily for all eyes except for very early endophthalmitis.Intravitreal injections of antibiotics were performed in eyes with endophthalmitis in the very early stages and in eyes where vitrectomy was not available,and additional control of infection was needed after vitrectomy.Evisceration was performed in eyes with corneoscleral perforation,advanced endophthalmitis,perforation with preseptal or orbital cellulitis,uncontrolled infection,or severe pain with no vision.RESULTS:Mean(±standard deviation)age of the 18 patients with endophthalmitis was 64.5±12.2(range:32-84)y,and 14 patients(77.8%)were males.Endophthalmitis tended to involve the retinal parenchyma first and then progressed into the vitreous cavity and anterior segments.However,it presented a tendency to cause massive subretinal abscesses even after vitrectomy with silicone oil tamponade.Very high intraocular pressure with new vessels on the iris(41.7%)were also commonly observed.Although all but three patients had systemic disease such as diabetes or hypertension,visual prognosis after treatment did not appear to depend significantly on underlying comorbidities.A final best-corrected visual acuity better than 20/60 was achieved only when lesions were detected very early,with relatively good initial visual acuity,likely reflecting lower bacterial inoculation in the eye.CONCLUSION:Detection of early endophthalmitis lesions appears to be the only way to preserve good vision in patients with K.pneumoniae liver abscesses.Therefore,proper guidelines for ophthalmologic screening remain to be established for subjects at a high risk of endophthalmitis.
基金National Social Science Foundation Program,No.22VRC163National Natural Science Foundation of China,No.42061043+1 种基金Postgraduate Research&Practice Innovation Program of Jiangsu Province,No.KYCX24_1008Innovation Project of Guangxi Graduate Education,No.YCSW2024473。
文摘Clarifying the mechanisms that control the evolution of territorial space patterns is essential for regulating and optimizing the geographical structure and processes related to sustainable development.Using the Guangdong and Guangxi sections of the Pearl River Basin as examples,the transfer-matrix method and standard deviation ellipse model were applied to characterize the evolution of territorial space patterns from 1990 to 2020.A trend surface analysis and the Theil index were used to analyze regional differences in the evolution process,and geodetectors were used to identify the underlying mechanisms of the changes.There were three key results.(1)In these critical areas of the Pearl River Basin,agricultural and ecological spaces have rapidly declined due to urban expansion,with transfers between these spaces dominating the evolution of territorial space patterns.Spatial pattern changes in the Guangdong section were more intense than in the Guangxi section.(2)Regional differences in urban space have decreased,whereas differences in agricultural and ecological spaces have intensified.Driven by socio-economic growth,the cross-regional transfers of territorial space have created a“high in the east,while low in the west”inter-regional difference,and a“high in the south,while low in the north”intra-regional difference shaped by natural conditions.The regional differences in space patterns were greater in Guangdong than in Guangxi.(3)The evolution of watershed territorial space patterns resulted from scale changes,locational shifts,structural reorganizations,and directional changes driven by multiple factors.Natural environment,social life,economic development,and policy factors played foundational,leading,key driving,and guiding roles,respectively.Additionally,the regional differences in the evolution of watershed territorial space patterns originated from the differential transmission of the influence of various factors affecting spatial evolution.Enhancing urban space efficiency,restructuring agricultural space,and optimizing ecological space are key strategies for building a complementary and synergistic territorial space pattern in the basin.