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Loss of the aryl hydrocarbon receptor promotes cancer cell resistance to BRAFV600E targeted therapies
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作者 Mourad Zerfaoui Dharmeshkumar Patel +2 位作者 Yueqi Zhang Raymond F.Schinazi Youssef Errami 《Signal Transduction and Targeted Therapy》 2025年第6期3067-3069,共3页
Dear Editor,Predicting a patient's response to cancer therapies and identifying additional molecular targets is crucial for advancing cancer treatment.BRAFvoe-specific inhibitors have demonstrated promising initia... Dear Editor,Predicting a patient's response to cancer therapies and identifying additional molecular targets is crucial for advancing cancer treatment.BRAFvoe-specific inhibitors have demonstrated promising initial clinical results in solid tumors;however,side effects and drug resistance are common,and for most patients,response to BRAFvoot inhibitor therapy is transient. 展开更多
关键词 brafvoot inhibitor identifying additional molecular targets patients Aryl Hydrocarbon Receptor drug resistance BRAF V E Drug Resistance solid tumorshoweverside effects
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