Immune-related receptor-like kinases(RLKs) and receptor-like cytoplasmic kinases(RLCKs) enable plant cells to rapidly transduce and amplify immune signals at an early stage of pathogen attack,which is essential for pl...Immune-related receptor-like kinases(RLKs) and receptor-like cytoplasmic kinases(RLCKs) enable plant cells to rapidly transduce and amplify immune signals at an early stage of pathogen attack,which is essential for plant survival,and these immune kinases must be tightly controlled to prevent aberrant activation.The U-box type E3 ubiquitin ligase SPL11(Os PUB11) has been shown to trigger the ubiquitination and degradation of the S-locus RLK SDS2 to attenuate immunity in rice.展开更多
The application of very large floating structure (VLFS) to the utilization of ocean space and exploitation of ocean resources has become one of the issues of great interest in international ocean engineering field. Ow...The application of very large floating structure (VLFS) to the utilization of ocean space and exploitation of ocean resources has become one of the issues of great interest in international ocean engineering field. Owing to the advantage of simplicity in structure and low cost of construction and maintenance, box-type VLFS can be used in the calm water area near the coast as the structure configuration of floating airport. In this paper, a 3D linear hydroelastic theory is used to study the dynamic response of box-type VLFS in sinusoidal regular waves. A beam model and a 3D FEM model are respectively employed to describe the dynamic characteristics of the box-type Structure in vacuum. A hydrodynamic model (3D potential theory of flexible body) is applied to investigate the effect of different dry models on the hydroelastic response of box-type structure. Based on the calculation of hydroelastic response in regular waves, the rigid body motion displacement, flexible deflection, and the short term and long term wave induced bending moments are also predicted.展开更多
The transcription factor forkhead box protein A2(FOXA2, also known as hepatocyte nuclear factor 3β or transcription factor 3β), has been found to play pivotal roles in multiple phases of mammalian life, from the ear...The transcription factor forkhead box protein A2(FOXA2, also known as hepatocyte nuclear factor 3β or transcription factor 3β), has been found to play pivotal roles in multiple phases of mammalian life, from the early development to the organofaction, and subsequently in homeostasis and metabolism in the adult. In the embryonic development period, FOXA2 is require d for the formation of the primitive node and notochord, and its absence results in embryonic lethality. Moreover, FOXA2 plays an important role not only in lung development, but also in T helper type 2(Th2)-mediated pulmonary inflammation and goblet cell hyperplasia. In this article, the role of FOXA2 in lung development and Th2-mediated pulmonary inflammation, as well as in goblet cell hyperplasia, is reviewed. FOXA2 deletion in airway epithelium results into Th2-mediated pulmonary inflammation and goblet cell hyperplasia in developing lung. Leukotriene pathway and signal transducers and activators of transcription 6 pathway may mediate this inflammation through recruitment and activation of denditric cell during lung developments. FOXA2 is a potential treatment target for lung diseases with Th2 inflammation and goblet cell hyperplasia, such as asthma and chronic obstructive pulmonary disease.展开更多
A box-type solar cooker with an inclined surface, equipped with a concentration reflector to allow maximum energy to be collected, enabled cooking tests to be carried out in the rainy season. Different thermocouples w...A box-type solar cooker with an inclined surface, equipped with a concentration reflector to allow maximum energy to be collected, enabled cooking tests to be carried out in the rainy season. Different thermocouples were implanted on various places of the cooker. The temperature measurements from these sensors were taken every 10 minutes.<span><span><span style="font-family:;" "=""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">The tests presented in this article relate to the preparation of eggs and rice. The absorber temperatures during the tests exceeded 100<span style="white-space:nowrap;">°</span>C. The cooking times were between 1</span></span></span><span><span><span style="font-family:;" "=""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">h</span></span></span><span><span><span style="font-family:;" "=""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">50</span></span></span><span><span><span style="font-family:;" "=""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">min and 2</span></span></span><span><span><span style="font-family:;" "=""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">h</span></span></span><span><span><span style="font-family:;" "=""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">20 min despite the numerous cloudy periods. The cooker made it possible to reach sufficient temperatures for healthy cooking of food. The results obtained for these first tests are satisfactory and very encouraging.</span></span></span>展开更多
MIKCC-type MADS-box genes encode transcription factors that are involved in plant developmental control and signal transduction. Few Gossypium hirsutum MADS-box genes have been reported thus far. Recently, the genome ...MIKCC-type MADS-box genes encode transcription factors that are involved in plant developmental control and signal transduction. Few Gossypium hirsutum MADS-box genes have been reported thus far. Recently, the genome of Gossypium raimondii, considering the contributor of the D subgenome to G. hirsutum, was sequenced and provided a valuable resource to identify and analyze multiple MADS-box genes in G. hirsutum. Here we comprehensively analyzed 53 MIKCC-type MADS-box genes, including 34 newly cloned genes. Phylogenetic analysis of these genes with those from Arabidopsis and grapevine showed that the FLC and AGL12 subfamilies were absent in G. hirsutum. Proteins within a gene subfamily tended to share conserved motifs, and large differences occurred among subfamilies. Expression analysis in multiple tissues and lforal organs implied differing roles for the subfamilies in G. hirsutum. At nine loci, two or three genes co-occurred, indicating that they came from different subgenomes; these groups had similar expression patterns. The identiifcation of MIKCC-type MADS-box genes in G. hirsutum provides a valuable resource for further research into lfowering time, lfower development and ovule development in this important crop plant.展开更多
In order to ensure the construction quality and safety of small and medium span basket type steel box tied arch bridge,this paper takes a practical project as an example to analyze the key technologies in its design p...In order to ensure the construction quality and safety of small and medium span basket type steel box tied arch bridge,this paper takes a practical project as an example to analyze the key technologies in its design process.It is hoped that this analysis can provide corresponding reference for the design and construction of this kind of arch bridge.展开更多
A series of fundamental experimental investigation was conducted in order to examine the effect of PWHT by sheet-type ceramic heater on the residual stress, deformation and compressive behavior of non-stiffened welded...A series of fundamental experimental investigation was conducted in order to examine the effect of PWHT by sheet-type ceramic heater on the residual stress, deformation and compressive behavior of non-stiffened welded box columns. The sheet-type ceramic heater was able to control the required temperature history for PWHT with high accuracy. The welding-induced tensile and compressive residual stresses of the specimens were reduced by 90% and 76% respectively with PWHT. Besides, PWHT could reduce the welding-induced out-of-plane deformation by 22%. It was revealed that the PWHT specimens had a slight higher stiffness than the As-welded specimens when applying monotonic static compressive load on both As-welded and PWHT specimens. They could also enhance the ultimate compressive load capacity about 32% of that of the As-welded specimens. The effectiveness of PWHT with the sheet-type ceramic heater could be confirmed.展开更多
基金supported by the Innovation Program of Chinese Academy of Agricultural Sciences (CAAS-CSCB202301) to Y.N.the National Natural Science Foundation of China (U24A20388) to R.W.
文摘Immune-related receptor-like kinases(RLKs) and receptor-like cytoplasmic kinases(RLCKs) enable plant cells to rapidly transduce and amplify immune signals at an early stage of pathogen attack,which is essential for plant survival,and these immune kinases must be tightly controlled to prevent aberrant activation.The U-box type E3 ubiquitin ligase SPL11(Os PUB11) has been shown to trigger the ubiquitination and degradation of the S-locus RLK SDS2 to attenuate immunity in rice.
基金This work was financially supported by the National Natural Science Foundation of China (Grant No. 50039010)
文摘The application of very large floating structure (VLFS) to the utilization of ocean space and exploitation of ocean resources has become one of the issues of great interest in international ocean engineering field. Owing to the advantage of simplicity in structure and low cost of construction and maintenance, box-type VLFS can be used in the calm water area near the coast as the structure configuration of floating airport. In this paper, a 3D linear hydroelastic theory is used to study the dynamic response of box-type VLFS in sinusoidal regular waves. A beam model and a 3D FEM model are respectively employed to describe the dynamic characteristics of the box-type Structure in vacuum. A hydrodynamic model (3D potential theory of flexible body) is applied to investigate the effect of different dry models on the hydroelastic response of box-type structure. Based on the calculation of hydroelastic response in regular waves, the rigid body motion displacement, flexible deflection, and the short term and long term wave induced bending moments are also predicted.
基金The National Natural Science Foundation of China,Nos.30871118,30971325,81270129 and 81470268(FL)grants from Department of Science and Technology of Sichuan Province,Nos.09ZQ026-020 and 2009SZ0190(FL)
文摘The transcription factor forkhead box protein A2(FOXA2, also known as hepatocyte nuclear factor 3β or transcription factor 3β), has been found to play pivotal roles in multiple phases of mammalian life, from the early development to the organofaction, and subsequently in homeostasis and metabolism in the adult. In the embryonic development period, FOXA2 is require d for the formation of the primitive node and notochord, and its absence results in embryonic lethality. Moreover, FOXA2 plays an important role not only in lung development, but also in T helper type 2(Th2)-mediated pulmonary inflammation and goblet cell hyperplasia. In this article, the role of FOXA2 in lung development and Th2-mediated pulmonary inflammation, as well as in goblet cell hyperplasia, is reviewed. FOXA2 deletion in airway epithelium results into Th2-mediated pulmonary inflammation and goblet cell hyperplasia in developing lung. Leukotriene pathway and signal transducers and activators of transcription 6 pathway may mediate this inflammation through recruitment and activation of denditric cell during lung developments. FOXA2 is a potential treatment target for lung diseases with Th2 inflammation and goblet cell hyperplasia, such as asthma and chronic obstructive pulmonary disease.
文摘A box-type solar cooker with an inclined surface, equipped with a concentration reflector to allow maximum energy to be collected, enabled cooking tests to be carried out in the rainy season. Different thermocouples were implanted on various places of the cooker. The temperature measurements from these sensors were taken every 10 minutes.<span><span><span style="font-family:;" "=""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">The tests presented in this article relate to the preparation of eggs and rice. The absorber temperatures during the tests exceeded 100<span style="white-space:nowrap;">°</span>C. The cooking times were between 1</span></span></span><span><span><span style="font-family:;" "=""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">h</span></span></span><span><span><span style="font-family:;" "=""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">50</span></span></span><span><span><span style="font-family:;" "=""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">min and 2</span></span></span><span><span><span style="font-family:;" "=""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">h</span></span></span><span><span><span style="font-family:;" "=""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">20 min despite the numerous cloudy periods. The cooker made it possible to reach sufficient temperatures for healthy cooking of food. The results obtained for these first tests are satisfactory and very encouraging.</span></span></span>
基金supported by the National High-Tech R&D Program of China (2011AA10A102)the Earmarked Fund for China Agriculture Research System (CARS-18)
文摘MIKCC-type MADS-box genes encode transcription factors that are involved in plant developmental control and signal transduction. Few Gossypium hirsutum MADS-box genes have been reported thus far. Recently, the genome of Gossypium raimondii, considering the contributor of the D subgenome to G. hirsutum, was sequenced and provided a valuable resource to identify and analyze multiple MADS-box genes in G. hirsutum. Here we comprehensively analyzed 53 MIKCC-type MADS-box genes, including 34 newly cloned genes. Phylogenetic analysis of these genes with those from Arabidopsis and grapevine showed that the FLC and AGL12 subfamilies were absent in G. hirsutum. Proteins within a gene subfamily tended to share conserved motifs, and large differences occurred among subfamilies. Expression analysis in multiple tissues and lforal organs implied differing roles for the subfamilies in G. hirsutum. At nine loci, two or three genes co-occurred, indicating that they came from different subgenomes; these groups had similar expression patterns. The identiifcation of MIKCC-type MADS-box genes in G. hirsutum provides a valuable resource for further research into lfowering time, lfower development and ovule development in this important crop plant.
文摘In order to ensure the construction quality and safety of small and medium span basket type steel box tied arch bridge,this paper takes a practical project as an example to analyze the key technologies in its design process.It is hoped that this analysis can provide corresponding reference for the design and construction of this kind of arch bridge.
文摘A series of fundamental experimental investigation was conducted in order to examine the effect of PWHT by sheet-type ceramic heater on the residual stress, deformation and compressive behavior of non-stiffened welded box columns. The sheet-type ceramic heater was able to control the required temperature history for PWHT with high accuracy. The welding-induced tensile and compressive residual stresses of the specimens were reduced by 90% and 76% respectively with PWHT. Besides, PWHT could reduce the welding-induced out-of-plane deformation by 22%. It was revealed that the PWHT specimens had a slight higher stiffness than the As-welded specimens when applying monotonic static compressive load on both As-welded and PWHT specimens. They could also enhance the ultimate compressive load capacity about 32% of that of the As-welded specimens. The effectiveness of PWHT with the sheet-type ceramic heater could be confirmed.
