The reactions of tri-2-benzofuranylborane or aminoethyl di-2-thienylborinate and 2-thienylphenylborinate with dichlorocarbene generated in situ from chloroform under phase transfer conditions were explored as a new ro...The reactions of tri-2-benzofuranylborane or aminoethyl di-2-thienylborinate and 2-thienylphenylborinate with dichlorocarbene generated in situ from chloroform under phase transfer conditions were explored as a new route for the preparation of heteroaromatic ketones. It was found that a good yield of the ketones can be obtained by solid-liquid system.展开更多
Plantation Chinese fir wood was modified by low molecular weight phenol melamine urea formaldehyde(PMUF)resin and boron compounds(BB)through a progressive gradual infiltration process.The results showed that the limit...Plantation Chinese fir wood was modified by low molecular weight phenol melamine urea formaldehyde(PMUF)resin and boron compounds(BB)through a progressive gradual infiltration process.The results showed that the limiting oxygen index(LOI)values,density,dimensional stability and static flexural properties of the PMUF resin treated wood gradually improved with the increase of resin solid content.When boron compounds were additionally introduced into the PMUF resin,the density and the LOI values of the samples of compound modification increased,whereas the anti-swelling efficiency,the modulus of rupture and impact toughness decreased by more than 17.6%,10.1%and 42.9%,respectively.It was demonstrated by X-ray diffraction and Fourier transform infrared spectroscopy that boron compounds could improve the crystallinity of resin modified samples and did not have a chemical reaction with resin or wood.Scanning electron microscope analysis indicated boron compounds made the microstructure of the resin polymers loose,influencing the mechanical properties and dimensional stability of resin modified wood.展开更多
The ubiquitousness of naturally occurring boron-containing compounds(BCCs) has led to their constant contact with humankind.Recently,many synthetic BCCs have been elaborated for a broad spectrum of purposes,especially...The ubiquitousness of naturally occurring boron-containing compounds(BCCs) has led to their constant contact with humankind.Recently,many synthetic BCCs have been elaborated for a broad spectrum of purposes,especially boric,boronic and borinic acids.Although BCCs were once employed primarily as antiseptics and later as antibiotics,they have become an increasingly relevant therapeutic tool.Nevertheless,this potential of BCCs has been drastically limited due to some unfortunate intra-hospital accidents in the 1940 s and 1950 s.The increasing use of BCCs as insecticides,antimicrobials,and other agents is providing new insights into their role in the physiology of several living species and in the pathophysiology of humans.It is becoming clear that BCCs act through a wide range of mechanisms,as do their corresponding boron-free counterparts.When comparing BCCs and similar boron-free compounds,in many cases the former show advantages in the medical field.The current minireview focuses on how BCCs have been developed by means of translational medicine,a process connecting biomedical research with clinical applications.This process of discovery is currently in an exponential stage.展开更多
By using AP-FIM the varity of the ordered degree of Ni_3Al with L1_2 structure with B content was studied. The possibility of boron improving ductility was also discussed from bonding between Ni and Al atoms, and anti...By using AP-FIM the varity of the ordered degree of Ni_3Al with L1_2 structure with B content was studied. The possibility of boron improving ductility was also discussed from bonding between Ni and Al atoms, and antisite defects in Ni_3Al. The extent of ordering is reduced with an increase in boron content and the autisite defects are most obvious for 0.52at.K B-doped sample that has the best ductility. Some results were verified by X-ray diffraction non. The addition of boron not only influences electron environment at grain boundary but also in the interior of Ni_3Al gm ins, the latter is favorable to improve the ductility of Ni_3Al grains.展开更多
Boronic acid compounds with different substituted groups were handled to synthesize various ligands encoded as B1, B2, B3, B4, BS, B6, B7 and BS. B5 and B7 were tested for the cytotoxic activity against the prostate c...Boronic acid compounds with different substituted groups were handled to synthesize various ligands encoded as B1, B2, B3, B4, BS, B6, B7 and BS. B5 and B7 were tested for the cytotoxic activity against the prostate cancer cells and it was found that the cell viability of cancer cells was decreased while most of the healthy cells could still be viable. 5 μM solutions of B5 and B7 decreased the cell viability to 33% and 44%; whereas healthy cells were 71% and 95%, respectively, after treatment. Antimicrobial properties were explored against the bacterial and fungal microorganisms with B1, B5 and BZ The inhibition zones were evaluated for all boronic structures, and the growth inhibition zones were determined in a range of 7-13 mm diameter for different microorganism species. Staphylococcus aureus was the common micro- organism that three boronic compounds with imine ligands showed the activity. Antioxidant features of B2, B3, B4, B5, B6, B7 and B8 were investigated by different processes such as Beta-carotene bleaching （BCB）, 2,2-diphenyl picryl hydrazyl （DPPH）, 2,2″-azino-bis（ 3-ethylbenzothiazoline-6-sulphonic acid） （ABTS） and CUPric reducing antioxidant capacity （CLIPRAC） methods. Significant antioxidant activity was achieved by the phenyl boronic based ligands and these compounds demonstrated as much activity as standards （α-Toc and BHT）. In addition, all structures were applied properly without any decomposition during the experiments. They were rather stable both in aqueous media and solid state.展开更多
Purpose: In defining the biological effects of the 10B(n, α)7Li neutron capture reaction, we have previously developed a deterministic parsing model to determine the Compound Biological Effectiveness (CBE) factor in ...Purpose: In defining the biological effects of the 10B(n, α)7Li neutron capture reaction, we have previously developed a deterministic parsing model to determine the Compound Biological Effectiveness (CBE) factor in Borono-Phenyl-Alanine (BPA)-mediated Boron Neutron Capture Therapy (BNCT). In present paper, we demonstrate that the CBE factor is directly and unambiguously derivable by the new formula for any case of intracellular 10Boron (10B) distribution, which is founded on this model for tissues and tumor. Method: To determine the CBE factor, we derive the following new calculation formula founded on the deterministic parsing model with three constants, CBE0, F, n and the eigen value Nth/Nmax. where, Nth and Nmax are the threshold value of boron concentration of N and saturation boron density in tissues and tumor. In order to determine these constants and the eigen values, iterative calculation technique was employed for the CEB factor and Nmax data set previously reported. Results and Conclusion: From the iterative calculation results, it is clear that the calculated CBE factor values obtained are almost identical to the original CBE factors and there is a good correlation between the original CBE factors and Nth/Nmax, when CBE0, F and n are given as 0.5, 8 and 3, respectively. These constants provide a better understanding of different types of intracellular10B distribution.展开更多
The Curie temperature of(Nd_(1-x)Pr_x)_2Fe_(14)Co_yB compounds(x=0,0.2,…,1.0 and y=O,2,4,6,14)has been determined with AC initial susceptibility measurement.It was found that the variations of Curie tempera- ture wit...The Curie temperature of(Nd_(1-x)Pr_x)_2Fe_(14)Co_yB compounds(x=0,0.2,…,1.0 and y=O,2,4,6,14)has been determined with AC initial susceptibility measurement.It was found that the variations of Curie tempera- ture with x is not linear for y=0 and 14,whereas it is linear for other values of y.The lattice constants of (Nd_(1-x)Pr_x)_2Fet_(14)B were determined by using X-ray diffraction.The lattice expansion was mostly along the c axis,whereas that along the a-axis remained practically zero for the whole series.It is suggested that Pr atoms may show site preference in R_2M_(14)B compounds(M=Fe or Co).Due to the substitution of Co for Fe.the tendency of site preference of Pr becomes less pronounced,which may be attributed to the decrease of differ- ence of crystal electric field(CEF)acting on the two rare earth sites with the introduction of Co or Fe.In con- trast to that of the Pr atoms,the site preference of Co iu(Nd(1-x)Pr_x)_2Fe(14-y)Co_yB compounds does not depend on the composition of the rare earth sublattice(R=N d or Pr).展开更多
Purpose: In defining the biological effects of the 10B(n, α)7Li neutron capture reaction, we have proposed a deterministic parsing model (ISHIYAMA-IMAHORI model) to determine the Compound Biological Effectiveness (CB...Purpose: In defining the biological effects of the 10B(n, α)7Li neutron capture reaction, we have proposed a deterministic parsing model (ISHIYAMA-IMAHORI model) to determine the Compound Biological Effectiveness (CBE) factor in Borono-Phenyl-Alanine (BPA)-mediated Boron Neutron Capture Therapy (BNCT). In present paper, we demonstrate a specific method of how the application of the case of application to actual patient data, which is founded on this model for tissues and tumor. Method: To determine the CBE factor, we derived the following new calculation formula founded on the deterministic parsing model with three constants, CBE0, F, n and the eigen value Nth/Nmax.? (1), where, Nth and Nmax are the threshold value of boron concentration of N and saturation boron density and CBE0, F and n are given as 0.5, 8 and 3, respectively. In order to determine Nth and Nmax in the formula, sigmoid logistic function was employed for 10B concentration data, Db(t) obtained by dynamic PET technique. (2), where, A, a and t0 are constants. Results and Conclusion: From the application of sigmoid function to dynamic PET data, it is concluded that the Nth and Nmax for tissue and tumor are identified with the parameter constants in the sigmoid function in Equation (2) as: (3). And the calculated CBE factor values obtained from Equation (1), with Nth/Nmax.展开更多
The effect of boron content(0 to 2.22 at.-% )on isothermal oxidation behaviour of Ni_3Al at 750 to 1150℃ for 3 to 100 h has been studied.The results show that the isothermal oxidation kinetics of Ni_3Al with various ...The effect of boron content(0 to 2.22 at.-% )on isothermal oxidation behaviour of Ni_3Al at 750 to 1150℃ for 3 to 100 h has been studied.The results show that the isothermal oxidation kinetics of Ni_3Al with various B contents at different temperatures obeys the parabolic law. The compounds with 0.52 to 1.37 at.-%B show the best oxidation resistance.The morphology and microstructure of the scales have also been investigated.展开更多
Solid state B-offerings (FeB compound) were used for plasma-assisted boronizing on Ti6Al4V alloy by double glow discharge plasma alloying technique (DGPSA). During all experiment processing there was no harmful and to...Solid state B-offerings (FeB compound) were used for plasma-assisted boronizing on Ti6Al4V alloy by double glow discharge plasma alloying technique (DGPSA). During all experiment processing there was no harmful and toxic. The thickness and morphology, phase formation, elements concentrations and wear properties of boride layers were examined by means of optical microscopy, Vickers microhardness, X-ray diffraction, glow discharge optical emission spectroscopy and Ball-disk wear tests. The results show that friction coefficient of boride alloying samples versus corundum ball is lower than that of Ti6Al4V samples, as well as wear rate. This indicates that plasma-assisted boronizing of Ti6Al4V alloy has a high potential for industrial applications under tribological conditions.展开更多
文摘The reactions of tri-2-benzofuranylborane or aminoethyl di-2-thienylborinate and 2-thienylphenylborinate with dichlorocarbene generated in situ from chloroform under phase transfer conditions were explored as a new route for the preparation of heteroaromatic ketones. It was found that a good yield of the ketones can be obtained by solid-liquid system.
基金12th Five-Year Key Technology R&D Program of China(No.2015BAD14B01)for their financial support of this research.
文摘Plantation Chinese fir wood was modified by low molecular weight phenol melamine urea formaldehyde(PMUF)resin and boron compounds(BB)through a progressive gradual infiltration process.The results showed that the limiting oxygen index(LOI)values,density,dimensional stability and static flexural properties of the PMUF resin treated wood gradually improved with the increase of resin solid content.When boron compounds were additionally introduced into the PMUF resin,the density and the LOI values of the samples of compound modification increased,whereas the anti-swelling efficiency,the modulus of rupture and impact toughness decreased by more than 17.6%,10.1%and 42.9%,respectively.It was demonstrated by X-ray diffraction and Fourier transform infrared spectroscopy that boron compounds could improve the crystallinity of resin modified samples and did not have a chemical reaction with resin or wood.Scanning electron microscope analysis indicated boron compounds made the microstructure of the resin polymers loose,influencing the mechanical properties and dimensional stability of resin modified wood.
基金Supported by Secretaria de Investigación y Posgrado del Instituto Politécnico Nacional,No.SIP-1754 20170411the National Council of Science and Technology,No.CONACYT,CB-235785
文摘The ubiquitousness of naturally occurring boron-containing compounds(BCCs) has led to their constant contact with humankind.Recently,many synthetic BCCs have been elaborated for a broad spectrum of purposes,especially boric,boronic and borinic acids.Although BCCs were once employed primarily as antiseptics and later as antibiotics,they have become an increasingly relevant therapeutic tool.Nevertheless,this potential of BCCs has been drastically limited due to some unfortunate intra-hospital accidents in the 1940 s and 1950 s.The increasing use of BCCs as insecticides,antimicrobials,and other agents is providing new insights into their role in the physiology of several living species and in the pathophysiology of humans.It is becoming clear that BCCs act through a wide range of mechanisms,as do their corresponding boron-free counterparts.When comparing BCCs and similar boron-free compounds,in many cases the former show advantages in the medical field.The current minireview focuses on how BCCs have been developed by means of translational medicine,a process connecting biomedical research with clinical applications.This process of discovery is currently in an exponential stage.
基金This project was supported by the National Nature Science Foundation of China!(Grant No.59831020 and 59895156)
文摘By using AP-FIM the varity of the ordered degree of Ni_3Al with L1_2 structure with B content was studied. The possibility of boron improving ductility was also discussed from bonding between Ni and Al atoms, and antisite defects in Ni_3Al. The extent of ordering is reduced with an increase in boron content and the autisite defects are most obvious for 0.52at.K B-doped sample that has the best ductility. Some results were verified by X-ray diffraction non. The addition of boron not only influences electron environment at grain boundary but also in the interior of Ni_3Al gm ins, the latter is favorable to improve the ductility of Ni_3Al grains.
基金Dicle University Science and Technology Research Center(DUBTAM)Dicle University Scientific and Technological Research Council(DUBAP)with Grant Number:14–EZF–14 are gratefully acknowledged for their analysis and financial supports
文摘Boronic acid compounds with different substituted groups were handled to synthesize various ligands encoded as B1, B2, B3, B4, BS, B6, B7 and BS. B5 and B7 were tested for the cytotoxic activity against the prostate cancer cells and it was found that the cell viability of cancer cells was decreased while most of the healthy cells could still be viable. 5 μM solutions of B5 and B7 decreased the cell viability to 33% and 44%; whereas healthy cells were 71% and 95%, respectively, after treatment. Antimicrobial properties were explored against the bacterial and fungal microorganisms with B1, B5 and BZ The inhibition zones were evaluated for all boronic structures, and the growth inhibition zones were determined in a range of 7-13 mm diameter for different microorganism species. Staphylococcus aureus was the common micro- organism that three boronic compounds with imine ligands showed the activity. Antioxidant features of B2, B3, B4, B5, B6, B7 and B8 were investigated by different processes such as Beta-carotene bleaching （BCB）, 2,2-diphenyl picryl hydrazyl （DPPH）, 2,2″-azino-bis（ 3-ethylbenzothiazoline-6-sulphonic acid） （ABTS） and CUPric reducing antioxidant capacity （CLIPRAC） methods. Significant antioxidant activity was achieved by the phenyl boronic based ligands and these compounds demonstrated as much activity as standards （α-Toc and BHT）. In addition, all structures were applied properly without any decomposition during the experiments. They were rather stable both in aqueous media and solid state.
文摘Purpose: In defining the biological effects of the 10B(n, α)7Li neutron capture reaction, we have previously developed a deterministic parsing model to determine the Compound Biological Effectiveness (CBE) factor in Borono-Phenyl-Alanine (BPA)-mediated Boron Neutron Capture Therapy (BNCT). In present paper, we demonstrate that the CBE factor is directly and unambiguously derivable by the new formula for any case of intracellular 10Boron (10B) distribution, which is founded on this model for tissues and tumor. Method: To determine the CBE factor, we derive the following new calculation formula founded on the deterministic parsing model with three constants, CBE0, F, n and the eigen value Nth/Nmax. where, Nth and Nmax are the threshold value of boron concentration of N and saturation boron density in tissues and tumor. In order to determine these constants and the eigen values, iterative calculation technique was employed for the CEB factor and Nmax data set previously reported. Results and Conclusion: From the iterative calculation results, it is clear that the calculated CBE factor values obtained are almost identical to the original CBE factors and there is a good correlation between the original CBE factors and Nth/Nmax, when CBE0, F and n are given as 0.5, 8 and 3, respectively. These constants provide a better understanding of different types of intracellular10B distribution.
基金This work was partly supported by National Science Foundation(No.5870025)Magnetism Laboratory,Institute of Physics,Academia Sinica,Bejing,P.R.China.
文摘The Curie temperature of(Nd_(1-x)Pr_x)_2Fe_(14)Co_yB compounds(x=0,0.2,…,1.0 and y=O,2,4,6,14)has been determined with AC initial susceptibility measurement.It was found that the variations of Curie tempera- ture with x is not linear for y=0 and 14,whereas it is linear for other values of y.The lattice constants of (Nd_(1-x)Pr_x)_2Fet_(14)B were determined by using X-ray diffraction.The lattice expansion was mostly along the c axis,whereas that along the a-axis remained practically zero for the whole series.It is suggested that Pr atoms may show site preference in R_2M_(14)B compounds(M=Fe or Co).Due to the substitution of Co for Fe.the tendency of site preference of Pr becomes less pronounced,which may be attributed to the decrease of differ- ence of crystal electric field(CEF)acting on the two rare earth sites with the introduction of Co or Fe.In con- trast to that of the Pr atoms,the site preference of Co iu(Nd(1-x)Pr_x)_2Fe(14-y)Co_yB compounds does not depend on the composition of the rare earth sublattice(R=N d or Pr).
文摘Purpose: In defining the biological effects of the 10B(n, α)7Li neutron capture reaction, we have proposed a deterministic parsing model (ISHIYAMA-IMAHORI model) to determine the Compound Biological Effectiveness (CBE) factor in Borono-Phenyl-Alanine (BPA)-mediated Boron Neutron Capture Therapy (BNCT). In present paper, we demonstrate a specific method of how the application of the case of application to actual patient data, which is founded on this model for tissues and tumor. Method: To determine the CBE factor, we derived the following new calculation formula founded on the deterministic parsing model with three constants, CBE0, F, n and the eigen value Nth/Nmax.? (1), where, Nth and Nmax are the threshold value of boron concentration of N and saturation boron density and CBE0, F and n are given as 0.5, 8 and 3, respectively. In order to determine Nth and Nmax in the formula, sigmoid logistic function was employed for 10B concentration data, Db(t) obtained by dynamic PET technique. (2), where, A, a and t0 are constants. Results and Conclusion: From the application of sigmoid function to dynamic PET data, it is concluded that the Nth and Nmax for tissue and tumor are identified with the parameter constants in the sigmoid function in Equation (2) as: (3). And the calculated CBE factor values obtained from Equation (1), with Nth/Nmax.
文摘The effect of boron content(0 to 2.22 at.-% )on isothermal oxidation behaviour of Ni_3Al at 750 to 1150℃ for 3 to 100 h has been studied.The results show that the isothermal oxidation kinetics of Ni_3Al with various B contents at different temperatures obeys the parabolic law. The compounds with 0.52 to 1.37 at.-%B show the best oxidation resistance.The morphology and microstructure of the scales have also been investigated.
基金Project(50501016) supported by the National Natural Science Foundation of ChinaProjects(2006021023, 20051049) supported by the Natural Science Foundation of Shanxi provinceProject supported by Young Scholar of University of Shanxi Province
文摘Solid state B-offerings (FeB compound) were used for plasma-assisted boronizing on Ti6Al4V alloy by double glow discharge plasma alloying technique (DGPSA). During all experiment processing there was no harmful and toxic. The thickness and morphology, phase formation, elements concentrations and wear properties of boride layers were examined by means of optical microscopy, Vickers microhardness, X-ray diffraction, glow discharge optical emission spectroscopy and Ball-disk wear tests. The results show that friction coefficient of boride alloying samples versus corundum ball is lower than that of Ti6Al4V samples, as well as wear rate. This indicates that plasma-assisted boronizing of Ti6Al4V alloy has a high potential for industrial applications under tribological conditions.
