Semi-heterogeneous photocatalysis has emerged as a powerful and productive platform in organic chemistry,which provides mild and eco-friendly conditions for a diverse range of bond-forming reactions.The synergy of hom...Semi-heterogeneous photocatalysis has emerged as a powerful and productive platform in organic chemistry,which provides mild and eco-friendly conditions for a diverse range of bond-forming reactions.The synergy of homogeneous catalysts and heterogeneous catalysts inherits their main advantages,such as higher activities,easy separation and superior recyclability.In this review,we summarize the recent advances in recyclable semi-heterogenous protocols for the light promoted bond-forming reactions and identify directions for future research according to the different photocatalysts/metal/redox catalysts involved.Notably,this review is not a comprehensive description of reported literature but aim to highlight and illustrate key concepts,strategies,reaction model,reaction conditions and mechanisms.展开更多
Herein,a series of carbazolyl cyanobenzene(CCB)-based organic photocatalysts with a broad range of photoredox capabilities were designed and synthesized,allowing precise control of the photocatalytic reactivity for th...Herein,a series of carbazolyl cyanobenzene(CCB)-based organic photocatalysts with a broad range of photoredox capabilities were designed and synthesized,allowing precise control of the photocatalytic reactivity for the controllable reduction of aryl halides via a metal-free process.The screened-out CCB(5CzBN),a metal-free,low-cost,scalable and sustainable photocatalyst with both strong oxidative and reductive ability,exhibits superior performance for both dehalogenation and C—C bond-forming arylation reactions.展开更多
An interesting and recyclable activated carbon/water catalytic system for efficient synthesis of pyrrolo[1,2-a]quinoxaline derivatives was developed. The intramolecular C-N and C-C bond can be easily constructed in wa...An interesting and recyclable activated carbon/water catalytic system for efficient synthesis of pyrrolo[1,2-a]quinoxaline derivatives was developed. The intramolecular C-N and C-C bond can be easily constructed in water under mild condition. This reaction features a broad substrate scope, a good tolerance to water and air, metal-free, additive-free and redox reagent-free.展开更多
As readily available and abundant industrial feedstocks,alkenes have emerged as versatile platform for constructing value-added targets.Transition metal-catalyzed dicarbofunctionalizations reactions forge two carbon-c...As readily available and abundant industrial feedstocks,alkenes have emerged as versatile platform for constructing value-added targets.Transition metal-catalyzed dicarbofunctionalizations reactions forge two carbon-carbon bonds in one step with construction of two vicinal saturated carbon centers,providing profound synthetic potential in organic synthesis and pharmaceutical chemistry.In particular,nickel-catalyzed reductive dicarbofunctionalization of alkenes has witnessed remarkable progress in recent years.Compared to conventional redox-neutral dicarbofunctionalization strategy,reductive variant offers significant advantages,such as no use of pre-formed organometallic reagents,operational simplicity and mild reaction conditions.This review summarizes developments of nickel-catalyzed reductive dicarbofunctionalization of alkenes to forge diverse carbon-carbon bonds in the absence of stoichiometric carbon nucleophiles.The mechanistic considerations are comprehensively discussed,including two-electron migratory insertion and the single-electron radical addition pathways.Furthermore,we provide critical insights into future directions and potential challenges in this area,highlighting opportunities for further methodology development and applications for nickel-catalyzed reductive dicarbofunctionalization of alkenes.展开更多
文摘Semi-heterogeneous photocatalysis has emerged as a powerful and productive platform in organic chemistry,which provides mild and eco-friendly conditions for a diverse range of bond-forming reactions.The synergy of homogeneous catalysts and heterogeneous catalysts inherits their main advantages,such as higher activities,easy separation and superior recyclability.In this review,we summarize the recent advances in recyclable semi-heterogenous protocols for the light promoted bond-forming reactions and identify directions for future research according to the different photocatalysts/metal/redox catalysts involved.Notably,this review is not a comprehensive description of reported literature but aim to highlight and illustrate key concepts,strategies,reaction model,reaction conditions and mechanisms.
基金the National Natural Scie nce Foundation of China(No.21972094)Guangdong Special Support Program+2 种基金Pengcheng Scholar programShenzhen Peacock Plan(Nos.KQJSCX20170727100802505,KQTD2016053112042971)the Educational Commission of Guangdong Province(No.2016KTSCX126)。
文摘Herein,a series of carbazolyl cyanobenzene(CCB)-based organic photocatalysts with a broad range of photoredox capabilities were designed and synthesized,allowing precise control of the photocatalytic reactivity for the controllable reduction of aryl halides via a metal-free process.The screened-out CCB(5CzBN),a metal-free,low-cost,scalable and sustainable photocatalyst with both strong oxidative and reductive ability,exhibits superior performance for both dehalogenation and C—C bond-forming arylation reactions.
基金the financial support from the National Natural Science Foundation of China (Nos. 21432009, 21672200, 21472177, 21772185 and 21801233)for the assistance of the product characterization from the Chemistry Experiment Teaching Center of University of Science and Technology of Chinasupported by the Strategic Priority Research Program of the Chinese Academy of Sciences (No. XDB20000000)
文摘An interesting and recyclable activated carbon/water catalytic system for efficient synthesis of pyrrolo[1,2-a]quinoxaline derivatives was developed. The intramolecular C-N and C-C bond can be easily constructed in water under mild condition. This reaction features a broad substrate scope, a good tolerance to water and air, metal-free, additive-free and redox reagent-free.
基金Financial support from National Natural Science Foundation of China(22171127,22371115,and 22373056)Natural Science Foundation of Sichuan Province(25NSFSC2247)+6 种基金Sichuan Science and Technology Program(2024ZYD0017)Shenzhen Science and Technology Innovation Committee(JCYJ20240813094226034,JCYJ20230807093522044)the Pearl River Talent Recruitment Program(2019QN01Y261)Guangdong Provincial Key Laboratory of Catalysis(2020B121201002)Scientific Research and Innovation Team Program of Sichuan University of Science and Engineering(No.SUSE652A014)the Innovation Fund of Postgraduate from Sichuan University of Science&Engineering(Y2024079,Y2024087)is thankedsupported by the SUSTech-NUS Joint Research Program.
文摘As readily available and abundant industrial feedstocks,alkenes have emerged as versatile platform for constructing value-added targets.Transition metal-catalyzed dicarbofunctionalizations reactions forge two carbon-carbon bonds in one step with construction of two vicinal saturated carbon centers,providing profound synthetic potential in organic synthesis and pharmaceutical chemistry.In particular,nickel-catalyzed reductive dicarbofunctionalization of alkenes has witnessed remarkable progress in recent years.Compared to conventional redox-neutral dicarbofunctionalization strategy,reductive variant offers significant advantages,such as no use of pre-formed organometallic reagents,operational simplicity and mild reaction conditions.This review summarizes developments of nickel-catalyzed reductive dicarbofunctionalization of alkenes to forge diverse carbon-carbon bonds in the absence of stoichiometric carbon nucleophiles.The mechanistic considerations are comprehensively discussed,including two-electron migratory insertion and the single-electron radical addition pathways.Furthermore,we provide critical insights into future directions and potential challenges in this area,highlighting opportunities for further methodology development and applications for nickel-catalyzed reductive dicarbofunctionalization of alkenes.
