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Preparation and performance evaluation of sand consolidation and water blocking system for loose sandstone reservoir
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作者 Zhiwei Huang Yongqian Jian +1 位作者 Mingqiang Zhou Jinlong Liu 《日用化学工业(中英文)》 北大核心 2025年第11期1395-1401,共7页
Sand production and high water content in oil wells are two major challenges that restrict high and stable production in loose sandstone reservoirs.In this paper,nano SiO_(2),coupling agent triethoxysilane,phenolic re... Sand production and high water content in oil wells are two major challenges that restrict high and stable production in loose sandstone reservoirs.In this paper,nano SiO_(2),coupling agent triethoxysilane,phenolic resin and n-octanol were used to synthesize the main agent SCA-2.Hexamethylenetetramine and vinyl carbonate were selected to prepare the curing agent YGA-1,which was then compounded with SCA-2 to develop a sand fixation and water plugging system.Firstly,single-factor experiments were conducted to determine the optimal concentrations of SCA-2 and YGA-1,subsequently,the system’s sand fixation and water blocking performance were evaluated.Finally,a pilot test was carried out in the mining site.Experimental results showed that the optimal formula composition of the system was 10%SCA-2+5%YGA-1.The gelation time of the system was 180 minutes and the viscosity after gelation could reach 108.4 mPa·s.When the dosage of the drug system was 0.6 PV,the sand production rate remained below 0.08%.Dual-tube parallel experiments showed that the sand fixation and water plugging system had a water flow channel plugging rate of 87.5%,while the oil flow channel plugging rate was only 11.3%,indicating minimal damage to the oil-bearing reservoir.The field test showed that after the measures taken in Well M of X oilfield,the sand free oil recovery period exceeded 360 days,the water content decreased by 5.0%and the cumulative oil production increased by 7092 m^(3).This study provides new ideas for efficient development of loose sandstone reservoirs. 展开更多
关键词 solidify sand and block water loose sandstone formula optimization performance evaluation field test
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Type WYZ-97 Eighteen information Noninsulate Frequency shift Automatic Blocking System
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作者 陈志龙 《High Technology Letters》 EI CAS 2000年第3期38-39,共2页
Type WYZ 97 eighteen information noninsulate frequency shift automatic blocking system is the most advanced railroad signaling system in China nowadays.The article introduced its principles,technical targets,features ... Type WYZ 97 eighteen information noninsulate frequency shift automatic blocking system is the most advanced railroad signaling system in China nowadays.The article introduced its principles,technical targets,features and the applications. 展开更多
关键词 Frequency shift Automatic blocking Noninsulate Eighteen information
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The Role Played by Blocking System over North America on the Development of Hurricane Ophelia over North Atlantic Ocean
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作者 Yehia Hafez Abdulhaleem Labban 《Journal of Geoscience and Environment Protection》 2018年第12期1-20,共20页
As one of very rare and unusual tracks of hurricane Ophelia, it exists over the North Atlantic Ocean during the period of 9-17 October 2017. The present work investigates the role played by blocking system over North ... As one of very rare and unusual tracks of hurricane Ophelia, it exists over the North Atlantic Ocean during the period of 9-17 October 2017. The present work investigates the role played by blocking system over North America on the development of hurricane Ophelia. The 6-hour daily data of NCEP/NCAR reanalysis composites for the meteorological parameters are used. The meteorological elements used in the present work are (geopotential height and meridional wind components at 500-hpa level). The domain of this data is the northern hemisphere domain. Moreover, the 6-hour data on the surface pressure at the center of hurricane Ophelia and its maximum wind through the period (9-17 October) have been used. The time series, anomaly and correlation coefficient methods have been used to analyze the meteorological data. The results revealed that the persistence of blocking high system over the North America during the period of 9-17 October 2017 controls the development, strength, and the track of hurricane Ophelia over the North Atlantic Ocean. 展开更多
关键词 blocking system NORTH AMERICA NORTH ATLANTIC Ocean HURRICANE OPHELIA
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Review of Infrared signature suppression systems using optical blocking method 被引量:18
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作者 Nidhi Baranwal Shripad P. Mahulikar 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2019年第3期432-439,共8页
With rapid advancements in Infra-Red (IR) detection techniques, the range from where the IR-guided missiles are able to lock the target aircraft has increased. To avoid the detection and tracking by modern IR-guided m... With rapid advancements in Infra-Red (IR) detection techniques, the range from where the IR-guided missiles are able to lock the target aircraft has increased. To avoid the detection and tracking by modern IR-guided missiles, the aircraft and helicopters also demand progress in its stealth techniques. Hence, study of Infra-Red Signature Suppression (IRSS) systems in aircraft and helicopters has become vital even in design stage. Optical blocking (masking) is one of the effective IRSS techniques used to block the Line- Of-Sight (LOS) of the hot engine parts of the exhaust geometry. This paper reviews the various patents on IR signature suppression systems based on the optical blocking method or a combination of IRSS techniques. The performance penalties generated due to installation of various IRSS methods in aircraft and helicopters are also discussed. 展开更多
关键词 IR SIGNATURE SUPPRESSION OPTICAL blocking Performance PENALTY IR SIGNATURE level Engine back-pressure
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Electric Wheelchair Control System Using Brain-Computer Interface Based on Alpha-Wave Blocking 被引量:2
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作者 明东 付兰 +8 位作者 陈龙 汤佳贝 綦宏志 赵欣 周鹏 张力新 焦学军 王春慧 万柏坤 《Transactions of Tianjin University》 EI CAS 2014年第5期358-363,共6页
A brain-computer interface(BCI)-based electric wheelchair control system was developed, which enables the users to move the wheelchair forward or backward, and turn left or right without any pre-learning. This control... A brain-computer interface(BCI)-based electric wheelchair control system was developed, which enables the users to move the wheelchair forward or backward, and turn left or right without any pre-learning. This control system makes use of the amplitude enhancement of alpha-wave blocking in electroencephalogram(EEG) when eyes close for more than 1 s to constitute a BCI for the switch control of wheelchair movements. The system was formed by BCI control panel, data acquisition, signal processing unit and interface control circuit. Eight volunteers participated in the wheelchair control experiments according to the preset routes. The experimental results show that the mean success control rate of all the subjects was 81.3%, with the highest reaching 93.7%. When one subject's triggering time was 2.8 s, i.e., the flashing time of each cycle light was 2.8 s, the average information transfer rate was 8.10 bit/min, with the highest reaching 12.54 bit/min. 展开更多
关键词 electric wheelchair alpha-wave blocking brain-computer interface (BCI) success control rate
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Coil Ambient Temperature and Its Influence on the Formation of Blocking Layer in the Electromagnetic Induction-Controlled Automated Steel-Teeming System 被引量:1
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作者 Ming He Xian-Liang Li +3 位作者 Xing-An Liu Xiao-Wei Zhu Tie Liu Qiang Wang 《Acta Metallurgica Sinica(English Letters)》 SCIE EI CAS CSCD 2019年第3期391-400,共10页
Ambient temperature of induction coil is an important factor to influence the implementation of the electromagnetic induction-controlled automated steel-teeming(EICAST) technology. Meanwhile, it also affects the forma... Ambient temperature of induction coil is an important factor to influence the implementation of the electromagnetic induction-controlled automated steel-teeming(EICAST) technology. Meanwhile, it also affects the formation of Fe–C alloy blocking layer, which determines the length and installation position of induction coil. An experimental platform was designed to imitate actual working conditions in a ladle with the EICAST system. Ambient temperature of induction coil under high-temperature condition was measured to verify the accuracy of numerical result. After containing molten steel for 120 min and steel teeming for 40 min, the ambient temperature on the upper side of induction coil is 791 °C. In addition, the position of blocking layer in a 110 t ladle was measured by sand-collection and steel-pour methods, and the criterion temperatures of blocking layer in numerical simulation process were corrected. When the refining temperature is1600 °C and the containing time of molten steel is 120 min, the thickness of blocking layer is 130 mm, and the distance between the upper surface of blocking layer and the upper surface of nozzle brick is 154 mm. When the criterion temperatures are 919 °C and 428 °C, the numerical results can be used to confirm the position of blocking layer and the installation position of induction coil. 展开更多
关键词 CLEAN STEEL EICAST technology Heat TRANSFER blocking layer COIL AMBIENT temperature
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A Nonlinear Multi-Scale Interaction Model for Atmospheric Blocking:A Tool for Exploring the Impact of Changing Climate on Mid-to-High Latitude Weather Extremes 被引量:1
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作者 Dehai LUO Wenqi ZHANG Binhe LUO 《Advances in Atmospheric Sciences》 2025年第10期2018-2035,共18页
A nonlinear multi-scale interaction(NMI)model was proposed and developed by the first author for nearly 30 years to represent the evolution of atmospheric blocking.In this review paper,we first review the creation and... A nonlinear multi-scale interaction(NMI)model was proposed and developed by the first author for nearly 30 years to represent the evolution of atmospheric blocking.In this review paper,we first review the creation and development of the NMI model and then emphasize that the NMI model represents a new tool for identifying the basic physics of how climate change influences mid-to-high latitude weather extremes.The building of the NMI model took place over three main periods.In the 1990s,a nonlinear Schr?dinger(NLS)equation model was presented to describe atmospheric blocking as a wave packet;however,it could not depict the lifetime(10-20 days)of atmospheric blocking.In the 2000s,we proposed an NMI model of atmospheric blocking in a uniform basic flow by making a scale-separation assumption and deriving an eddyforced NLS equation.This model succeeded in describing the life cycle of atmospheric blocking.In the 2020s,the NMI model was extended to include the impact of a changing climate mainly by altering the basic zonal winds and the magnitude of the meridional background potential vorticity gradient(PVy).Model results show that when PVy is smaller,blocking has a weaker dispersion and a stronger nonlinearity,so blocking can be more persistent and have a larger zonal scale and weaker eastward movement,thus favoring stronger weather extremes.However,when PVy is much smaller and below a critical threshold under much stronger winter Arctic warming of global warming,atmospheric blocking becomes locally less persistent and shows a much stronger westward movement,which acts to inhibit local cold extremes.Such a case does not happen in summer under global warming because PVy fails to fall below the critical threshold.Thus,our theory indicates that global warming can render summer-blocking anticyclones and mid-to-high latitude heatwaves more persistent,intense,and widespread. 展开更多
关键词 nonlinear Schrödinger equation nonlinear multi-scale interaction model of atmospheric blocking meridional background potential vorticity gradient climate change mid-to-high latitude weather extremes
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A Novel Approach to Practical Matrix Converter Motor Drive System With Reverse Blocking IGBT (To continue)
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《变频器世界》 2006年第8期28-29,共2页
a Pole voltage waveforms (VA20 and VA40) for modulation index 0.4 (middle trace is A-phase voltage waveform) x-axis: 1 div.=10ms, y-axis: 1 div.= 100V b Normalized harmonic spectrum for pole voltage of Fig. 9a c A-pha... a Pole voltage waveforms (VA20 and VA40) for modulation index 0.4 (middle trace is A-phase voltage waveform) x-axis: 1 div.=10ms, y-axis: 1 div.= 100V b Normalized harmonic spectrum for pole voltage of Fig. 9a c A-phase current and phase voltage for modulation index 0.4 (reference space vector is in inner layer) 展开更多
关键词 口口 口门 mode To continue A Novel Approach to Practical Matrix Converter Motor Drive system With Reverse blocking IGBT
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Max-min security energy efficiency optimization for UAV-RIS-enhanced short-packet communication systems 被引量:1
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作者 Zhengqiang WANG Kunhao HUANG +3 位作者 Yongjun XU Bin DUO Chengyu WU Liuwei HUO 《Chinese Journal of Aeronautics》 2025年第10期271-285,共15页
This work focuses on maximizing the minimum user’s security energy efficiency(SEE)in an unmanned aerial vehicle-mounted reconfigurable intelligent surface(UAV-RIS)enhanced short-packet communication(SPC)system.The ba... This work focuses on maximizing the minimum user’s security energy efficiency(SEE)in an unmanned aerial vehicle-mounted reconfigurable intelligent surface(UAV-RIS)enhanced short-packet communication(SPC)system.The base station(BS)provides short packet services to ground users using the non-orthogonal multiple access(NOMA)protocol through UAV-RIS,while preventing eavesdropper attacks.To optimize SEE,a joint optimization is performed concerning power allocation,UAV position,decoding order,and RIS phase shifts.An iterative algorithm based on block coordinate descent is proposed for mixed-integer non-convex SEE optimization problem.The original problem is decomposed into three sub-problems,solved alternately using successive convex approximation(SCA),quadratic transformation,penalty function,and semi-definite programming(SDP).Simulation results demonstrate the performance of the UAV-RIS-enhanced short-packet system under different parameters and verify the algorithm’s convergence.Compared to benchmark schemes such as orthogonal multiple access,long packet communication,and sum SEE,the proposed UAV-RIS-enhanced short-packet scheme achieves the higher minimum user’s SEE. 展开更多
关键词 Block coordinate descent Non-orthogonal multiple access(NOMA) Reconfigurable intelligent surface(RIS) Security energy efficiency(SEE) Short-packet communication Unmanned aerial vehicle(UAV)
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A Novel Approach to Practical Matrix Converter Motor Drive System With Reverse Blocking IGBT
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《变频器世界》 2006年第7期25-26,共2页
a Pole voltage waveforms (VA20 and VA40) for modulation index 0.4 (middle trace is A-phase voltage waveform) x-axis: 1 div.=10ms, y-axis: 1 div.= 100V b Normalized harmonic spectrum for pole voltage of Fig. 9a c A-pha... a Pole voltage waveforms (VA20 and VA40) for modulation index 0.4 (middle trace is A-phase voltage waveform) x-axis: 1 div.=10ms, y-axis: 1 div.= 100V b Normalized harmonic spectrum for pole voltage of Fig. 9a c A-phase current and phase voltage for modulation index 0.4 (reference space vector is in inner layer) 展开更多
关键词 A Novel Approach to Practical Matrix Converter Motor Drive system With Reverse blocking IGBT mode PWM
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Chloride-Ion Blocking in Seawater Electrolysis:Narrating the Tale of Likes and Dislikes Between Anode and Ions
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作者 Ashish Gaur Enkhtuvshin Enkhbayar +2 位作者 Jatin Sharma Sungwook Mhin HyukSu Han 《Energy & Environmental Materials》 2025年第1期255-272,共18页
Seawater is the most abundant source of molecular hydrogen.Utilizing the hydrogen reserves present in the seawater may inaugurate innovative strategies aimed at advancing sustainable energy and environmental preservat... Seawater is the most abundant source of molecular hydrogen.Utilizing the hydrogen reserves present in the seawater may inaugurate innovative strategies aimed at advancing sustainable energy and environmental preservation endeavors in the future.Recently,there has been a surge in study in the field addressing the production of hydrogen through the electrochemical seawater splitting.However,the performance and durability of the electrode have limitations due to the fact that there are a few challenges that need to be addressed in order to make the technology suitable for the industrial purpose.The active site blockage caused by chloride ions that are prevalent in seawater and chloride corrosion is the most significant issue;it has a negative impact on both the activity and the durability of the anode component.Addressing this particular issue is of upmost importance in the seawater splitting area.This review concentrates on the newly developed materials and techniques for inhibiting chloride ions by blocking the active sites,simultaneously preventing the chloride corrosion.It is anticipated that the concept will be advantageous for a large audience and will inspire researchers to study on this particular area of concern. 展开更多
关键词 chloride ion blocking ELECTROCATALYSIS Lewis acid oxygen evolution reaction seawater electrolysis
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High quantum yield yellow emission carbon dots for the construction of blue light blocking films
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作者 Liwen Wang Boyang Wang +2 位作者 Siyu Lu Shubo Lv Xiaoli Qu 《Chinese Chemical Letters》 2025年第2期216-221,共6页
White light illumination is essential in daily life,however,the substantial amount of blue light it contains can damage human eyes.Therefore,it is important to block this high-energy blue light to protect visual healt... White light illumination is essential in daily life,however,the substantial amount of blue light it contains can damage human eyes.Therefore,it is important to block this high-energy blue light to protect visual health.In this study,yellow-emitting carbon dots(CDs)with a quantum yield exceeding 94%were synthesized using citric acid and urea.These CDs effectively absorb blue light.By incorporating them into polystyrene,multiple films termed CDs-based blue light blocking films(CBFs)were developed,each offering different levels of blue light absorption.These CBFs exhibited excellent transparency and efficient blue light filtering capabilities.This study highlights the potential of high quantum yield CDs,which specifically absorb blue light,as foundational materials for developing light-blocking solutions against highenergy short-wavelength light. 展开更多
关键词 Carbon dots High quantum yield Controllable preparation Blue light blocking Composite film
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Effect of the Blocking High-East Asian Trough on Three Extreme Cold Events in Eastern Asia
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作者 Ziqun ZHANG Hongyan CUI +4 位作者 Fangli QIAO Baoxu CHEN Yang SONG Xiaohui SUN Chang GAO 《Advances in Atmospheric Sciences》 2025年第5期892-903,共12页
Three extreme cold events occurred in eastern Asia in January 2016,January 2021,and December 2023.As important factors in atmospheric circulation anomalies,the Blocking High and East Asian Trough(BH-ET)structure playe... Three extreme cold events occurred in eastern Asia in January 2016,January 2021,and December 2023.As important factors in atmospheric circulation anomalies,the Blocking High and East Asian Trough(BH-ET)structure played key roles during these three extreme cold wave events.Among these two dynamic patterns,the BH affected the development of the cold waves in two different ways:(1)before the cold waves in 2016 and 2023,the BH pushed the cold air southward,resulting in a slow and gradual cooling,with a cooling rate(CR)in eastern Asia of 1.34℃d^(-1)and 1.2℃d^(-1),respectively,and(2)in January 2021,the sudden collapse of BH caused the cold air to rapidly attack mid-latitude regions,with a CR of 1.87℃d^(-1).In terms of the spatial CR,the temperature drop in 2021 occurred 38.8%and 55%faster than those in 2016 and 2023,respectively.At the same time,the ET influences the wind direction of cold waves by modulating the pressure gradient.Before the cold waves occurred,the meridional wind field near the ET showed negative values,forming northwesterly or northeasterly winds,which continued to affect the southern part of East Asia.The meridional wind in January 2021 was stronger than those in 2016 and 2023,which is thought to be the reason for the strength of the 2021 cold wave.Finally,results from the temperature Empirical Orthogonal Function(EOF)analysis from 1980-2023 verify an obvious BH-ET structure in the three cold wave events,which suggests that this particular climatological state provides a climatic background for the occurrence of cold waves. 展开更多
关键词 extreme cold waves blocking high East Asian trough cooling rate
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Impact of proning with and without inhaled pulmonary vasodilators and neuromuscular blocking agents in COVID acute respiratory distress syndrome
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作者 Matthew Cabrera Sarika Bharil +2 位作者 Meghan Chin Seife Yohannes Paul Clark 《World Journal of Critical Care Medicine》 2025年第3期192-206,共15页
BACKGROUND A major cause of mortality in the coronavirus disease 2019(COVID-19)pandemic was acute respiratory distress syndrome(ARDS).Currently,moderate to severe ARDS induced by COVID-19(COVID ARDS)and other viral an... BACKGROUND A major cause of mortality in the coronavirus disease 2019(COVID-19)pandemic was acute respiratory distress syndrome(ARDS).Currently,moderate to severe ARDS induced by COVID-19(COVID ARDS)and other viral and non-viral etiologies are treated by traditional ARDS protocols that recommend 12-16 hours of prone position ventilation(PPV)with neuromuscular blocking agents(NMBA)and a trial of inhaled vasodilators(IVd)if oxygenation does not improve.However,debate on the efficacy of adjuncts to PPV and low tidal volume ventilation persists and evidence about the benefits of IVd/NMBA in COVID ARDS is sparse.In our multi-center retrospective review,we evaluated the impact of PPV,IVd,and NMBA on outcomes and lung mechanics in COVID ARDS patients with moderate to severe ARDS.AIM To evaluate the impact of PPV used alone or in combination with pulmonary IVd and/or NMBA in mechanically ventilated patients with moderate to severe ARDS during the COVID-19 pandemic.METHODS A retrospective study at two tertiary academic medical centers compared outcomes between COVID ARDS patients receiving PPV and patients in the supine position.PPV patients were divided based on concurrent use of ARDS adjunct therapies resulting in four subgroups:(1)PPV alone;(2)PPV and IVd;(3)PPV and NMBA;and(4)PPV,IVd,and NMBA.Primary outcomes were hospital and intensive care unit(ICU)length of stay(LOS),mortality,and venovenous extracorporeal membrane oxygenation(VV-ECMO)status.Secondary outcomes included changes in lung mechanics at 24-hour intervals for 7 days.RESULTS Total 114 patients were included in this study.Baseline respiratory parameters and Sequential Organ Failure Assessment scores were significantly worse in the PPV group.ICU LOS and LOS were significantly longer for patients who were proned,but no mortality benefit or difference in VV-ECMO status was found.Among the subgroups,no difference in primary outcomes were found.In the secondary analysis,PPV was associated with a significant improvement in arterial oxygen partial pressure(PaO_(2))/fractional inspired oxygen(FiO_(2))(P/F)ratio from day 1 to day 4(P<0.05)and higher driving pressures day 5 to day 7(P<0.05).The combination of PPV and IVd together resulted in improvements in P/F ratio from day 1 to day 7 and plateau pressure on day 4 and day 6(P<0.05).PPV with NMBA was not associated with improvements in any of the secondary outcomes.The use of all three rescue therapies together resulted in improvements in lung compliance on day 2(P<0.05)but no other improvements.CONCLUSION In mechanically ventilated patients diagnosed with moderate to severe COVID ARDS,PPV and PPV with the addition of IVd produced a significant and sustained increase in P/F ratio.The combination of PPV,IVd and NMBA improved compliance however this did not reach significance.Mortality and LOS did not improve with adjunct therapies.Further research is warranted to determine the efficacy of these therapies alone and in combination in the treatment of COVID ARDS. 展开更多
关键词 Acute respiratory distress syndrome COVID Prone position ventilation Neuromuscular blocking agents Pulmonary vasodilators Mechanical ventilation Plateau pressure Driving pressure Peak end expiratory pressure
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Deep Reinforcement Learning-based Multi-Objective Scheduling for Distributed Heterogeneous Hybrid Flow Shops with Blocking Constraints
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作者 Xueyan Sun Weiming Shen +3 位作者 Jiaxin Fan Birgit Vogel-Heuser Fandi Bi Chunjiang Zhang 《Engineering》 2025年第3期278-291,共14页
This paper investigates a distributed heterogeneous hybrid blocking flow-shop scheduling problem(DHHBFSP)designed to minimize the total tardiness and total energy consumption simultaneously,and proposes an improved pr... This paper investigates a distributed heterogeneous hybrid blocking flow-shop scheduling problem(DHHBFSP)designed to minimize the total tardiness and total energy consumption simultaneously,and proposes an improved proximal policy optimization(IPPO)method to make real-time decisions for the DHHBFSP.A multi-objective Markov decision process is modeled for the DHHBFSP,where the reward function is represented by a vector with dynamic weights instead of the common objectiverelated scalar value.A factory agent(FA)is formulated for each factory to select unscheduled jobs and is trained by the proposed IPPO to improve the decision quality.Multiple FAs work asynchronously to allocate jobs that arrive randomly at the shop.A two-stage training strategy is introduced in the IPPO,which learns from both single-and dual-policy data for better data utilization.The proposed IPPO is tested on randomly generated instances and compared with variants of the basic proximal policy optimization(PPO),dispatch rules,multi-objective metaheuristics,and multi-agent reinforcement learning methods.Extensive experimental results suggest that the proposed strategies offer significant improvements to the basic PPO,and the proposed IPPO outperforms the state-of-the-art scheduling methods in both convergence and solution quality. 展开更多
关键词 Multi-objective Markov decision process Multi-agent deep reinforcement learning Proximal policy optimization Distributed hybrid flow-shop scheduling blocking constraints
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A Unified Approach to Phase Equilibria in Multi-component Polymer Systems with Effective Chemical Potential
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作者 Wei-Ling Huang Yu-Chen Zhang Yi-Xin Liu 《Chinese Journal of Polymer Science》 2025年第9期1681-1689,I0014,共10页
Multi-component polymer systems exhibit exceptional versatility and structural diversity,making them indispensable in the polymer industry as well as in advanced and high performance applications.However,constructing ... Multi-component polymer systems exhibit exceptional versatility and structural diversity,making them indispensable in the polymer industry as well as in advanced and high performance applications.However,constructing accurate phase diagrams for these systems remains challenging due to inhomogeneous structures arising from the introduction of block copolymer components.Here,we present a unified and model-agnostic framework for computing phase equilibria in multi-component polymeric systems based on the concept of“effective chemical potential”.This approach directly connects key thermodynamic variables in the canonical ensemble to other ensembles,unifying phase coexistence determination without requiring the reformulation of self-consistent field theory(SCFT)calculations across different ensembles.By decoupling phase equilibrium determination from specific ensemble formulations,our approach enables the reuse of existing SCFT solvers.Moreover,it provides a useful framework to develop highly efficient phase equilibrium solvers for multi-component polymer systems. 展开更多
关键词 Polymer blends Chemical potential Phase equilibrium Block copolymers
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Cyclodextrins as versatile supramolecular building block in nanoscale drug delivery systems for precise tumor chemotherapy
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作者 Peng Liu 《Chinese Chemical Letters》 2025年第11期101-109,共9页
Nanoscale drug delivery systems(nano-DDSs)have attracted intense interest in tumor chemotherapy in the last decades,to improve antitumor efficacy and minimize toxic and side effects.As a versatile supramolecular build... Nanoscale drug delivery systems(nano-DDSs)have attracted intense interest in tumor chemotherapy in the last decades,to improve antitumor efficacy and minimize toxic and side effects.As a versatile supramolecular building block,cyclodextrins(CDs)have been widely used in the fabrication of the smart nano-DDSs.Besides their multifunctionality,which makes them versatile core in the star(co)polymers for micellar nanomedicines,specific host-vip inclusion complexation via their hydrophobic cavities endows them diversified functions:(i)design of amphiphilic copolymers for micellar nanomedicines,(ii)supramolecular hydrogels and poly(pseudo)rotaxane nano-hydrogels as drug carriers,and(iii)recipient for direct and indirect drug-loading.In the present work,the recent progress of CDs in nano-DDSs for tumor chemotherapy was reviewed,classified by the crucial roles of CD units.Based on the structureperformance relationship,the future perspective was also proposed. 展开更多
关键词 Nanoscale drug delivery system Cyclodextrins Supramolecular building block Tumor chemotherapy Structural design
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Ultrasound-guided erector spinae plane block for perioperative analgesia in laparoscopic nephrectomy:A systematic review and meta-analysis
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作者 Suhaina Amir Abdul Hannan Siddiqui +11 位作者 Muhammad Haris Fatima Laique Bushra Amini Mariam Mehboob Mubashir Mohiuddin Muhammad Mazhar Azam Sameen Mukhtar Zainab Akram Bibi Zainab Sahar Rizwan Abdul Moeed Salim Surani 《World Journal of Nephrology》 2025年第4期293-304,共12页
BACKGROUND Laparoscopic nephrectomy is a preferred surgical approach due to its minimally invasive nature and faster recovery times.However,effective management of postoperative pain remains a significant challenge.Se... BACKGROUND Laparoscopic nephrectomy is a preferred surgical approach due to its minimally invasive nature and faster recovery times.However,effective management of postoperative pain remains a significant challenge.Several traditional methods,including opioid-based analgesia,are commonly used but are associated with side effects such as nausea,vomiting,sedation,and delayed recovery.In recent years,the erector spinae plane block(ESPB)has gained attention as an ultrasoundguided regional anesthesia technique offering promising results in various surgical procedures by reducing opioid requirements and enhancing patient comfort.AIM To evaluate the efficacy and safety of ESPB in comparison to conventional pain management strategies in patients undergoing laparoscopic nephrectomy.METHODS Following PRISMA guidelines,we searched PubMed,EMBASE,Web of Science,and the Cochrane Register for randomized controlled trials(RCTs)comparing ESPB with control for laparoscopic nephrectomy.The Cochrane Risk of Bias tool was employed for quality assessment.The primary outcome was total patient-controlled analgesia(PCA)consumption.Secondary outcomes included hospital discharge time and the incidence of postoperative nausea and vomiting.A random-effects meta-analysis was conducted to calculate pooled mean differences(MD)and odds ratios(OR)with 95%CIs.RESULTS Nine RCTs involving a total of 643 patients(ESPB group=320;control group=323)were included in the analysis.ESPB significantly reduced PCA opioid consumption compared to controls(MD:-14.24,95%CI:-20.66 to-7.83,P<0.0001).Subgroup analysis showed reduced PCA use with ESPB vs morphine(MD:-8.78,95%CI:-15.34 to-2.22,P=0.009),and a non-significant effect compared to other analgesics(MD:-48.26,95%CI:-143.60 to 47.09).No statistically significant differences were observed in discharge time or the incidence of nausea and vomiting.CONCLUSION ESPB demonstrates the potential of reducing PCA in laparoscopic nephrectomy patients;however,its impact on secondary outcomes remains inconclusive.Large-scale RCTs are needed to confirm ESPB's benefits and explore long-term effects. 展开更多
关键词 Erector spinae plane block Laparoscopic nephrectomy Postoperative pain Opioid sparing Regional anesthesia NAUSEA Discharge time Minimally invasive surgery META-ANALYSIS
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Efficacy observation on herpes zoster treated by the comprehensive therapy of blocking, surrounding needling, pricking and cupping combined with bloodletting at Longyan(龙眼, Extra) acupoint 被引量:3
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作者 石跃 张喜鱼 +2 位作者 王建峰 赵紫昊 WANG Fang 《World Journal of Acupuncture-Moxibustion》 2013年第4期15-18,共4页
Objective To observe the analgesic effect on herpes zoster treated by the comprehensive therapy of blocking, surrounding needling, pricking and cupping combined with bloodletting at Longyan (龙眼, Extra) acupoint. M... Objective To observe the analgesic effect on herpes zoster treated by the comprehensive therapy of blocking, surrounding needling, pricking and cupping combined with bloodletting at Longyan (龙眼, Extra) acupoint. Methods According to the random mumber table, 104 cases of herpes zoster were randomized into an observation group and a control group, 52 cases in each one. In the observation group, the blocking method was used at the starting site and the ending site of herpetic zone, the surrounding needling method was applied toward the center of the painful zone, with horizontal needling technique; and the local pricking and cupping methods as well as the bloodletting at Longyan (Extra) acupoint were adopted. In the control group, Jiáj (夹脊 EX-B 2) at the corresponding affected nerve segments and the local Ashi points were selected and stimulated with electroacupuncture. The visual analogue scale (VAS) was adopted to determine the analgesic effect 20 min, 1, 6, 12, 24 and 48 h after treatment separately in each group. Results The onset time of analgesic effect in the observation group was shorter than that in the control group and the efficacy time of duration was longer than that in the control group (all P0.05). The analgesic effect and the result of comprehensive efficacy assessment were superior to those of the control group (both P0.05). Conclusion The comprehensive therapy of blocking, surrounding needling, pricking and cupping method combined with bloodletting at Longyan (Extra) achieves the significant analgesic effect on herpes zoster. 展开更多
关键词 herpes zoster blocking surrounding needling pricking andcupping bloodletting Longyan (龙眼 Extra) acupoint analgesia
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NUMERICAL ANALYSIS OF FLOW CHARACTERISTICS IN BLOCKING OF THE YANGTZ RIVER OF THE TGP 被引量:2
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作者 魏文礼 刘玉玲 金忠青 《Transactions of Tianjin University》 EI CAS 2001年第2期113-117,共5页
Some novel techniques of computational fluid dynamics are used to establish a mathematical model for the open diversion channel with two embankments in river blocking.The technique of boundary fitted coordinate syste... Some novel techniques of computational fluid dynamics are used to establish a mathematical model for the open diversion channel with two embankments in river blocking.The technique of boundary fitted coordinate system is used to overcome the difficulties resulting from the complicated shapes of natural river boundaries;the method of alternating direction implicit finite difference scheme is used to solve the partial differential equations in the transformed plane;and the technique of moving boundary is used to deal with the river bed exposed to water surface.This model has been used to predict the flow characteristics in the blocking of the Yangtz river in the Three Gorge Project (TGP).Comparison between the computed and experimental data shows a satisfactory agreement. 展开更多
关键词 river blocking flow characteristics mathematical model
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