Amphibious vehicles are more prone to attitude instability compared to ships,making it crucial to develop effective methods for monitoring instability risks.However,large inclination events,which can lead to instabili...Amphibious vehicles are more prone to attitude instability compared to ships,making it crucial to develop effective methods for monitoring instability risks.However,large inclination events,which can lead to instability,occur frequently in both experimental and operational data.This infrequency causes events to be overlooked by existing prediction models,which lack the precision to accurately predict inclination attitudes in amphibious vehicles.To address this gap in predicting attitudes near extreme inclination points,this study introduces a novel loss function,termed generalized extreme value loss.Subsequently,a deep learning model for improved waterborne attitude prediction,termed iInformer,was developed using a Transformer-based approach.During the embedding phase,a text prototype is created based on the vehicle’s operation log data is constructed to help the model better understand the vehicle’s operating environment.Data segmentation techniques are used to highlight local data variation features.Furthermore,to mitigate issues related to poor convergence and slow training speeds caused by the extreme value loss function,a teacher forcing mechanism is integrated into the model,enhancing its convergence capabilities.Experimental results validate the effectiveness of the proposed method,demonstrating its ability to handle data imbalance challenges.Specifically,the model achieves over a 60%improvement in root mean square error under extreme value conditions,with significant improvements observed across additional metrics.展开更多
This paper introduces a novel method for medical image retrieval and classification by integrating a multi-scale encoding mechanism with Vision Transformer(ViT)architectures and a dynamic multi-loss function.The multi...This paper introduces a novel method for medical image retrieval and classification by integrating a multi-scale encoding mechanism with Vision Transformer(ViT)architectures and a dynamic multi-loss function.The multi-scale encoding significantly enhances the model’s ability to capture both fine-grained and global features,while the dynamic loss function adapts during training to optimize classification accuracy and retrieval performance.Our approach was evaluated on the ISIC-2018 and ChestX-ray14 datasets,yielding notable improvements.Specifically,on the ISIC-2018 dataset,our method achieves an F1-Score improvement of+4.84% compared to the standard ViT,with a precision increase of+5.46% for melanoma(MEL).On the ChestX-ray14 dataset,the method delivers an F1-Score improvement of 5.3%over the conventional ViT,with precision gains of+5.0% for pneumonia(PNEU)and+5.4%for fibrosis(FIB).Experimental results demonstrate that our approach outperforms traditional CNN-based models and existing ViT variants,particularly in retrieving relevant medical cases and enhancing diagnostic accuracy.These findings highlight the potential of the proposedmethod for large-scalemedical image analysis,offering improved tools for clinical decision-making through superior classification and case comparison.展开更多
Control equation and adjoint equation are established by using block pulse functions, which transforms the linear time varying systems with time delays into a system of algebraic equations and the optimal control prob...Control equation and adjoint equation are established by using block pulse functions, which transforms the linear time varying systems with time delays into a system of algebraic equations and the optimal control problems are transformed into an optimization problem of multivariate functions thereby achieving the optimal control of linear systems with time delays.展开更多
In the early stages of traumatic spinal cord injury,extensive accumulation of autophagosomes creates a neurotoxic microenvironment,exacerbating neuronal cell death and worsening tissue damage,ultimately hindering neur...In the early stages of traumatic spinal cord injury,extensive accumulation of autophagosomes creates a neurotoxic microenvironment,exacerbating neuronal cell death and worsening tissue damage,ultimately hindering neurofunctional recovery.Activin A is a critical growth factor necessary for the development of the embryonic nervous system and for maintaining neuronal function in the adult cerebral cortex.It can inhibit excessive autophagy in ischemic stroke to reduce neuronal damage.However,the specific mechanism through which Activin A functions in the spinal cord remains poorly understood.In this study,we administered different concentrations of Activin A to neural stem cells from the spinal cord and found that Activin A stimulated the proliferation and neuronal differentiation of neural stem cells.Then,we established an in vitro oxidative stress model by using hydrogen peroxide to stimulate the neural stem cells-induced neurons.We found that Activin A could reduce apoptosis caused by oxidative stress.Subsequently,we treated a mouse model of spinal cord contusion with intrathecal injection of Activin A.Behavioral and electrophysiological results showed that Activin A promoted recovery of motor function and reconstruction of neural circuits in the model mice.Finally,RNA sequencing indicated that Activin A inhibited autophagy by activating the PI3K/AKT/mTOR pathway and upregulating the expression of synaptogenesis-related factor Sema3A in the spinal cord.These results suggest that Activin A may mediate the excessive autophagic response after spinal cord injury,promote the reconstruction of damaged neural circuits,and restore neurological function in the injured spinal cord.展开更多
Let and denote respectively the functionswhere λ≥1, The author discusses the similarity transformation of the regularizing functionals of these functions and the similar property of their Fourier transformation.
In the article, we present some refinements of three classes of transformation inequalities for zero-balanced hypergeometric functions by use of the updated monotonicity criterion for the quotient of power series.
Changes in soil biological and biochemical properties under different land uses in the subtropical region of China were investigated in order to develop rational cultivation and fertilization management. A small water...Changes in soil biological and biochemical properties under different land uses in the subtropical region of China were investigated in order to develop rational cultivation and fertilization management. A small watershed of subtropical region of China was selected for this study. Land uses covered paddy fields, vegetable farming, fruit trees, upland crops, bamboo stands, and forestry. Soil biological and biochemical properties included soil organic C and nutrient contents, mineralization of soil organic C, and soil microbial biomass and community functional diversity. Soil organic C and total N contents, microbial biomass C and N, and respiration intensity under different land uses were changed in the following order： paddy fields （and vegetable farming） 〉 bamboo stands 〉 fruit trccs （and upland）. The top surface （0-15 cm） paddy fields （and vegetable farming） were 76.4 and 80.8% higher in soil organic C and total N contents than fruit trees （and upland） soils, respectively. Subsurface paddy soils （15-30 cm） were 59.8 and 67.3% higher in organic C and total N than upland soils, respectively. Soil microbial C, N and respiration intensity in paddy soils （0-15 cm） were 6.36, 3.63 and 3.20 times those in fruit tree （and upland） soils respectively. Soil microbial metabolic quotient was in the order： fruit trees （and upland） 〉 forestry 〉 paddy fields. Metabolic quotient in paddy soils was only 47.7% of that in fruit tree （and upland） soils. Rates of soil organic C mineralization during incubation changed in the order： paddy fields 〉 bamboo stands 〉 fruit trees （and upland） and soil bacteria population： paddy fields 〉 fruit trees （and upland） 〉 forestry. No significant difference was found for fungi and actinomycetes populations. BIOLOG analysis indicated a changing order of paddy fields 〉 fruit trees （and upland） 〉 forestry in values of the average well cell development （AWCD） and functional diversity indexes of microbial community. Results also showed that the conversion from paddy fields to vegetable farming for 5 years resulted in a dramatic increase in soil available phosphorus content while insignificant changes in soil organic C and total N content due to a large inputs of phosphate fertilizers. This conversion caused 53, 41.5, and 41.3% decreases in soil microbial biomass C, N, and respiration intensity, respectively, while 23.6% increase in metabolic quotient and a decrease in soil organic C mineralization rate. Moreover, soil bacteria and actinomycetes populations were increased slightly, while fungi population increased dramatically. Functional diversity indexes of soil microbial community decreased significantly. It was concluded that land uses in the subtropical region of China strongly affected soil biological and biochemical properties. Soil organic C and nutrient contents, mineralization of organic C and functional diversity of microbial community in paddy fields were higher than those in upland and forestry. Overuse of chemical fertilizers in paddy fields with high fertility might degrade soil biological properties and biochemical function, resulting in deterioration of soil biological quality.展开更多
The probability distributions of wave characteristics from three groups of sampled ocean data with different significant wave heights have been analyzed using two transformation functions estimated by non-parametric a...The probability distributions of wave characteristics from three groups of sampled ocean data with different significant wave heights have been analyzed using two transformation functions estimated by non-parametric and parametric methods. The marginal wave characteristic distribution and the joint density of wave properties have been calculated using the two transformations, with the results and accuracy of both transformations presented here. The two transformations deviate slightly between each other for the calculation of the crest and trough height marginal wave distributions, as well as the joint densities of wave amplitude with other wave properties. The transformation methods for the calculation of the wave crest and trough height distributions are shown to provide good agreement with real ocean data. Our work will help in the determination of the most appropriate transformation procedure for the prediction of extreme values.展开更多
The theory of detecling ridges in the modulus of the continuous wavelet transform is presented as well as reconstructing signal by using information on ridges,To periodic signal we suppose Morlet wavelet as basic wave...The theory of detecling ridges in the modulus of the continuous wavelet transform is presented as well as reconstructing signal by using information on ridges,To periodic signal we suppose Morlet wavelet as basic wavelet, and research the local extreme point and extrema of the wavelet transform on periodic function for the collection of signal＇ s instantaneous amplitude and period.展开更多
We review the biology and role of transforming growth factor beta 1(TGF-β1)in peripheral nerve injury and regeneration,as it relates to injuries to large nerve trunks(i.e.,sciatic nerve,brachial plexus),which often l...We review the biology and role of transforming growth factor beta 1(TGF-β1)in peripheral nerve injury and regeneration,as it relates to injuries to large nerve trunks(i.e.,sciatic nerve,brachial plexus),which often leads to suboptimal functional recovery.Experimental studies have suggested that the reason for the lack of functional recovery resides in the lack of sufficient mature axons reaching their targets,which is a result of the loss of the growth-supportive environment provided by the Schwann cells in the distal stump of injured nerves.Using an established chronic nerve injury and delayed repair animal model that accu-rately mimics chronic nerve injuries in humans,we summarize our key findings as well as others to better understand the pathophysiology of poor functional recovery.We demonstrated that 6 month TGF-β1 treat-ment for chronic nerve injury significantly improved Schwann cell capacity to support axonal regeneration.When combined with forskolin,the effect was additive,as evidenced by a near doubling of regenerated axons proximal to the repair site.We showed that in vivo application of TGF-β1 and forskolin directly onto chronically injured nerves reactivated chronically denervated Schwann cells,induced their proliferation,and upregulated the expression of regeneration-associated proteins.The effect of TGF-β1 and forskolin on old nerve injuries is quite impressive and the treatment regiment appears to mediate a growth-supportive milieu in the injured peripheral nerves.In summary,TGF-β1 and forskolin treatment reactivates chronical-ly denervated Schwann cells and could potentially be used to extend and prolong the regenerative responses to promote axonal regeneration.展开更多
In China, most directions of river flowing are from west to east. During historic period, since the water traffic played an important role, it was very important to form a cross-horizontal net of water carriage route....In China, most directions of river flowing are from west to east. During historic period, since the water traffic played an important role, it was very important to form a cross-horizontal net of water carriage route. Canals should be dug so as to make up the lack of north-south river. Tongji Grand Canal, dug in the first year of Daye (605 A.D.) in the Sui Dynasty, was the important component of north-south system of Grand Canals in China. It promoted economic and social development of the Sui, Tang and Song dynasties (605 A.D.-1279 A.D.). As Tongji Canal (i.e. Tongji Grand Canal) flowed across the Huaibei Plain, which is aggraded by abundant mud and sand deposit resulted from the Huanghe (Yellow) River flooding, many traces (such as old channel) and human culture heritages were buried under mud-sand. Tongji Canal was silted up, and disappeared in the Jin Dynasty (1115 A.D.-1234 A.D.). From then on, there were many different stories about the flowing route of the canal in historical literature. Based on space-bone and air-bone remote sensing imagery, we attempt to search the old channel of Tongji Canal, and supplement historical record. The paper discusses transformation process of Tongji Canal’s traffic function, and resumptively summarizes the reasons of the transformation, which results from synthetic function of physical geographical, political, economic, and social conditions.展开更多
In this paper, an extended functional transformation is given to solve some nonlinear evolution equations. This function, in fact, is a solution of the famous KdV equation, so this transformation gives a transformatio...In this paper, an extended functional transformation is given to solve some nonlinear evolution equations. This function, in fact, is a solution of the famous KdV equation, so this transformation gives a transformation between KdV equation and other soliton equations. Then many new exact solutions can be given by virtue of the solutions of KdV equation.展开更多
The Auto-Transformer Rectifier Unit（ATRU） is one preferred solution for high-power AC/DC power conversion in aircraft. This is mainly due to its simple structure, high reliability and reduced k VA ratings. Indeed, t...The Auto-Transformer Rectifier Unit（ATRU） is one preferred solution for high-power AC/DC power conversion in aircraft. This is mainly due to its simple structure, high reliability and reduced k VA ratings. Indeed, the ATRU has become a preferred AC/DC solution to supply power to the electric environment control system on-board future aircraft. In this paper, a general modelling method for ATRUs is introduced. The developed model is based on the fact that the DC voltage and current are strongly related to the voltage and current vectors at the AC terminals of ATRUs. In this paper, we carry on our research in modelling symmetric 18-pulse ATRUs and develop a generic modelling technique. The developed generic model can study not only symmetric but also asymmetric ATRUs. An 18-pulse asymmetric ATRU is used to demonstrate the accuracy and efficiency of the developed model by comparing with corresponding detailed switching SABER models provided by our industrial partner. The functional models also allow accelerated and accurate simulations and thus enable whole-scale more-electric aircraft electrical power system studies in the future.展开更多
In order to provide larger capacity of the hidden secret data while maintaining a good visual quality of stego-image, in accordance with the visual property that human eyes are less sensitive to strong texture, a nove...In order to provide larger capacity of the hidden secret data while maintaining a good visual quality of stego-image, in accordance with the visual property that human eyes are less sensitive to strong texture, a novel steganographic method based on wavelet and modulus function is presented. First, an image is divided into blocks of prescribed size, and every block is decomposed into one-level wavelet. Then, the capacity of the hidden secret data is decided with the number of wavelet coefficients of larger magnitude. Finally, secret information is embedded by steganography based on modulus function. From the experimental results, the proposed method hides much more information and maintains a good visual quality of stego-image. Besides, the embedded data can be extracted from the stego-image without referencing the original image.展开更多
To elucidate feasible routes of producing CO from CH 3 and unravel the eff ect of adsorbed O on CH x transformation, the reactivity of CH x ( x = 1-3) with and without the assistance of adsorbed atomic O on Ni(111) wa...To elucidate feasible routes of producing CO from CH 3 and unravel the eff ect of adsorbed O on CH x transformation, the reactivity of CH x ( x = 1-3) with and without the assistance of adsorbed atomic O on Ni(111) was explored using density functional theory calculations. The adsorption energies of CH x ( x = 0-3) were found to be signifi cantly reduced on an O-preadsorbed Ni(111) surface compared to a pure surface. Furthermore, O-assisted one-step dehydrogenation of CH x ( x = 1-3) features energy barriers and thus is diffi cult to proceed. In terms of energy, the direct dissociation of CH 3 is favorable, except for the last CH dehydrogenation, which is energy intensive. Interestingly, in O-assisted two-step CH transformation to CO via CHO intermediate, the barrier is dramatically lowered. The successive dehydrogenations of CH x O ( x = 1-3) were also found to be a route for CO formation. Finally, two possible pathways from CH 3 to CO are proposed:(a) CH 3 → CH 2 → CH → CHO → CO;(b) CH 3 → CH 3 O → CH 2 O → CHO → CO.展开更多
基金Supported by the National Defense Basic Scientific Research Program of China.
文摘Amphibious vehicles are more prone to attitude instability compared to ships,making it crucial to develop effective methods for monitoring instability risks.However,large inclination events,which can lead to instability,occur frequently in both experimental and operational data.This infrequency causes events to be overlooked by existing prediction models,which lack the precision to accurately predict inclination attitudes in amphibious vehicles.To address this gap in predicting attitudes near extreme inclination points,this study introduces a novel loss function,termed generalized extreme value loss.Subsequently,a deep learning model for improved waterborne attitude prediction,termed iInformer,was developed using a Transformer-based approach.During the embedding phase,a text prototype is created based on the vehicle’s operation log data is constructed to help the model better understand the vehicle’s operating environment.Data segmentation techniques are used to highlight local data variation features.Furthermore,to mitigate issues related to poor convergence and slow training speeds caused by the extreme value loss function,a teacher forcing mechanism is integrated into the model,enhancing its convergence capabilities.Experimental results validate the effectiveness of the proposed method,demonstrating its ability to handle data imbalance challenges.Specifically,the model achieves over a 60%improvement in root mean square error under extreme value conditions,with significant improvements observed across additional metrics.
基金funded by the Deanship of Research and Graduate Studies at King Khalid University through small group research under grant number RGP1/278/45.
文摘This paper introduces a novel method for medical image retrieval and classification by integrating a multi-scale encoding mechanism with Vision Transformer(ViT)architectures and a dynamic multi-loss function.The multi-scale encoding significantly enhances the model’s ability to capture both fine-grained and global features,while the dynamic loss function adapts during training to optimize classification accuracy and retrieval performance.Our approach was evaluated on the ISIC-2018 and ChestX-ray14 datasets,yielding notable improvements.Specifically,on the ISIC-2018 dataset,our method achieves an F1-Score improvement of+4.84% compared to the standard ViT,with a precision increase of+5.46% for melanoma(MEL).On the ChestX-ray14 dataset,the method delivers an F1-Score improvement of 5.3%over the conventional ViT,with precision gains of+5.0% for pneumonia(PNEU)and+5.4%for fibrosis(FIB).Experimental results demonstrate that our approach outperforms traditional CNN-based models and existing ViT variants,particularly in retrieving relevant medical cases and enhancing diagnostic accuracy.These findings highlight the potential of the proposedmethod for large-scalemedical image analysis,offering improved tools for clinical decision-making through superior classification and case comparison.
文摘Control equation and adjoint equation are established by using block pulse functions, which transforms the linear time varying systems with time delays into a system of algebraic equations and the optimal control problems are transformed into an optimization problem of multivariate functions thereby achieving the optimal control of linear systems with time delays.
基金supported by the National Natural Science Foundation of China,Nos.82271419,81901902(to YZ),82202702(to ZW),82202351(to XH),82301550(to LYang),82271418(to XX)the Shanghai Rising-Star Program,No.22QA1408200(to YZ)the Fundamental Research Fundsfor the Central Universities,No.22120220555(to YZ).
文摘In the early stages of traumatic spinal cord injury,extensive accumulation of autophagosomes creates a neurotoxic microenvironment,exacerbating neuronal cell death and worsening tissue damage,ultimately hindering neurofunctional recovery.Activin A is a critical growth factor necessary for the development of the embryonic nervous system and for maintaining neuronal function in the adult cerebral cortex.It can inhibit excessive autophagy in ischemic stroke to reduce neuronal damage.However,the specific mechanism through which Activin A functions in the spinal cord remains poorly understood.In this study,we administered different concentrations of Activin A to neural stem cells from the spinal cord and found that Activin A stimulated the proliferation and neuronal differentiation of neural stem cells.Then,we established an in vitro oxidative stress model by using hydrogen peroxide to stimulate the neural stem cells-induced neurons.We found that Activin A could reduce apoptosis caused by oxidative stress.Subsequently,we treated a mouse model of spinal cord contusion with intrathecal injection of Activin A.Behavioral and electrophysiological results showed that Activin A promoted recovery of motor function and reconstruction of neural circuits in the model mice.Finally,RNA sequencing indicated that Activin A inhibited autophagy by activating the PI3K/AKT/mTOR pathway and upregulating the expression of synaptogenesis-related factor Sema3A in the spinal cord.These results suggest that Activin A may mediate the excessive autophagic response after spinal cord injury,promote the reconstruction of damaged neural circuits,and restore neurological function in the injured spinal cord.
文摘Let and denote respectively the functionswhere λ≥1, The author discusses the similarity transformation of the regularizing functionals of these functions and the similar property of their Fourier transformation.
基金supported by the Natural Science Foundation of China(61673169,11401191,11371125)the Tianyuan Special Funds of the Natural Science Foundation of China(11626101)the Natural Science Foundation of the Department of Education of Zhejiang Province(201635325)
文摘In the article, we present some refinements of three classes of transformation inequalities for zero-balanced hypergeometric functions by use of the updated monotonicity criterion for the quotient of power series.
基金the National Natural Science Foundation of China （40471066） the Knowledge Innovation Program of the Chinese Academy of Sciences （KZCX3-SW-417）.
文摘Changes in soil biological and biochemical properties under different land uses in the subtropical region of China were investigated in order to develop rational cultivation and fertilization management. A small watershed of subtropical region of China was selected for this study. Land uses covered paddy fields, vegetable farming, fruit trees, upland crops, bamboo stands, and forestry. Soil biological and biochemical properties included soil organic C and nutrient contents, mineralization of soil organic C, and soil microbial biomass and community functional diversity. Soil organic C and total N contents, microbial biomass C and N, and respiration intensity under different land uses were changed in the following order： paddy fields （and vegetable farming） 〉 bamboo stands 〉 fruit trccs （and upland）. The top surface （0-15 cm） paddy fields （and vegetable farming） were 76.4 and 80.8% higher in soil organic C and total N contents than fruit trees （and upland） soils, respectively. Subsurface paddy soils （15-30 cm） were 59.8 and 67.3% higher in organic C and total N than upland soils, respectively. Soil microbial C, N and respiration intensity in paddy soils （0-15 cm） were 6.36, 3.63 and 3.20 times those in fruit tree （and upland） soils respectively. Soil microbial metabolic quotient was in the order： fruit trees （and upland） 〉 forestry 〉 paddy fields. Metabolic quotient in paddy soils was only 47.7% of that in fruit tree （and upland） soils. Rates of soil organic C mineralization during incubation changed in the order： paddy fields 〉 bamboo stands 〉 fruit trees （and upland） and soil bacteria population： paddy fields 〉 fruit trees （and upland） 〉 forestry. No significant difference was found for fungi and actinomycetes populations. BIOLOG analysis indicated a changing order of paddy fields 〉 fruit trees （and upland） 〉 forestry in values of the average well cell development （AWCD） and functional diversity indexes of microbial community. Results also showed that the conversion from paddy fields to vegetable farming for 5 years resulted in a dramatic increase in soil available phosphorus content while insignificant changes in soil organic C and total N content due to a large inputs of phosphate fertilizers. This conversion caused 53, 41.5, and 41.3% decreases in soil microbial biomass C, N, and respiration intensity, respectively, while 23.6% increase in metabolic quotient and a decrease in soil organic C mineralization rate. Moreover, soil bacteria and actinomycetes populations were increased slightly, while fungi population increased dramatically. Functional diversity indexes of soil microbial community decreased significantly. It was concluded that land uses in the subtropical region of China strongly affected soil biological and biochemical properties. Soil organic C and nutrient contents, mineralization of organic C and functional diversity of microbial community in paddy fields were higher than those in upland and forestry. Overuse of chemical fertilizers in paddy fields with high fertility might degrade soil biological properties and biochemical function, resulting in deterioration of soil biological quality.
基金Supported by the Marine Engineering Equipment Scientific Research Project of Ministry of Industry and Information Technology of PRCthe National Science and Technology Major Project of China(Grant No.2016ZX05057020)National Natural Science Foundation of China(Grant No.51809067)
文摘The probability distributions of wave characteristics from three groups of sampled ocean data with different significant wave heights have been analyzed using two transformation functions estimated by non-parametric and parametric methods. The marginal wave characteristic distribution and the joint density of wave properties have been calculated using the two transformations, with the results and accuracy of both transformations presented here. The two transformations deviate slightly between each other for the calculation of the crest and trough height marginal wave distributions, as well as the joint densities of wave amplitude with other wave properties. The transformation methods for the calculation of the wave crest and trough height distributions are shown to provide good agreement with real ocean data. Our work will help in the determination of the most appropriate transformation procedure for the prediction of extreme values.
基金Supported by the National Natural Science Founda-tion of China (49771060)
文摘The theory of detecling ridges in the modulus of the continuous wavelet transform is presented as well as reconstructing signal by using information on ridges,To periodic signal we suppose Morlet wavelet as basic wavelet, and research the local extreme point and extrema of the wavelet transform on periodic function for the collection of signal＇ s instantaneous amplitude and period.
文摘We review the biology and role of transforming growth factor beta 1(TGF-β1)in peripheral nerve injury and regeneration,as it relates to injuries to large nerve trunks(i.e.,sciatic nerve,brachial plexus),which often leads to suboptimal functional recovery.Experimental studies have suggested that the reason for the lack of functional recovery resides in the lack of sufficient mature axons reaching their targets,which is a result of the loss of the growth-supportive environment provided by the Schwann cells in the distal stump of injured nerves.Using an established chronic nerve injury and delayed repair animal model that accu-rately mimics chronic nerve injuries in humans,we summarize our key findings as well as others to better understand the pathophysiology of poor functional recovery.We demonstrated that 6 month TGF-β1 treat-ment for chronic nerve injury significantly improved Schwann cell capacity to support axonal regeneration.When combined with forskolin,the effect was additive,as evidenced by a near doubling of regenerated axons proximal to the repair site.We showed that in vivo application of TGF-β1 and forskolin directly onto chronically injured nerves reactivated chronically denervated Schwann cells,induced their proliferation,and upregulated the expression of regeneration-associated proteins.The effect of TGF-β1 and forskolin on old nerve injuries is quite impressive and the treatment regiment appears to mediate a growth-supportive milieu in the injured peripheral nerves.In summary,TGF-β1 and forskolin treatment reactivates chronical-ly denervated Schwann cells and could potentially be used to extend and prolong the regenerative responses to promote axonal regeneration.
基金Under the auspices of the National Natural Science Foundation of China (No.40571162), the Natural Science Foun-dation of Anhui Province (No.050450401), Natural Science Foundation of Anhui Provincal Education Department (No.2004kj65zd), Postdoctoral Foundation of University of Science and Technology of China
文摘In China, most directions of river flowing are from west to east. During historic period, since the water traffic played an important role, it was very important to form a cross-horizontal net of water carriage route. Canals should be dug so as to make up the lack of north-south river. Tongji Grand Canal, dug in the first year of Daye (605 A.D.) in the Sui Dynasty, was the important component of north-south system of Grand Canals in China. It promoted economic and social development of the Sui, Tang and Song dynasties (605 A.D.-1279 A.D.). As Tongji Canal (i.e. Tongji Grand Canal) flowed across the Huaibei Plain, which is aggraded by abundant mud and sand deposit resulted from the Huanghe (Yellow) River flooding, many traces (such as old channel) and human culture heritages were buried under mud-sand. Tongji Canal was silted up, and disappeared in the Jin Dynasty (1115 A.D.-1234 A.D.). From then on, there were many different stories about the flowing route of the canal in historical literature. Based on space-bone and air-bone remote sensing imagery, we attempt to search the old channel of Tongji Canal, and supplement historical record. The paper discusses transformation process of Tongji Canal’s traffic function, and resumptively summarizes the reasons of the transformation, which results from synthetic function of physical geographical, political, economic, and social conditions.
文摘In this paper, an extended functional transformation is given to solve some nonlinear evolution equations. This function, in fact, is a solution of the famous KdV equation, so this transformation gives a transformation between KdV equation and other soliton equations. Then many new exact solutions can be given by virtue of the solutions of KdV equation.
文摘The Auto-Transformer Rectifier Unit（ATRU） is one preferred solution for high-power AC/DC power conversion in aircraft. This is mainly due to its simple structure, high reliability and reduced k VA ratings. Indeed, the ATRU has become a preferred AC/DC solution to supply power to the electric environment control system on-board future aircraft. In this paper, a general modelling method for ATRUs is introduced. The developed model is based on the fact that the DC voltage and current are strongly related to the voltage and current vectors at the AC terminals of ATRUs. In this paper, we carry on our research in modelling symmetric 18-pulse ATRUs and develop a generic modelling technique. The developed generic model can study not only symmetric but also asymmetric ATRUs. An 18-pulse asymmetric ATRU is used to demonstrate the accuracy and efficiency of the developed model by comparing with corresponding detailed switching SABER models provided by our industrial partner. The functional models also allow accelerated and accurate simulations and thus enable whole-scale more-electric aircraft electrical power system studies in the future.
基金the National Natural Science Foundation of China (50677014)Hunan Provincial Natural Science Foundation of China (06JJ50114).
文摘In order to provide larger capacity of the hidden secret data while maintaining a good visual quality of stego-image, in accordance with the visual property that human eyes are less sensitive to strong texture, a novel steganographic method based on wavelet and modulus function is presented. First, an image is divided into blocks of prescribed size, and every block is decomposed into one-level wavelet. Then, the capacity of the hidden secret data is decided with the number of wavelet coefficients of larger magnitude. Finally, secret information is embedded by steganography based on modulus function. From the experimental results, the proposed method hides much more information and maintains a good visual quality of stego-image. Besides, the embedded data can be extracted from the stego-image without referencing the original image.
文摘To elucidate feasible routes of producing CO from CH 3 and unravel the eff ect of adsorbed O on CH x transformation, the reactivity of CH x ( x = 1-3) with and without the assistance of adsorbed atomic O on Ni(111) was explored using density functional theory calculations. The adsorption energies of CH x ( x = 0-3) were found to be signifi cantly reduced on an O-preadsorbed Ni(111) surface compared to a pure surface. Furthermore, O-assisted one-step dehydrogenation of CH x ( x = 1-3) features energy barriers and thus is diffi cult to proceed. In terms of energy, the direct dissociation of CH 3 is favorable, except for the last CH dehydrogenation, which is energy intensive. Interestingly, in O-assisted two-step CH transformation to CO via CHO intermediate, the barrier is dramatically lowered. The successive dehydrogenations of CH x O ( x = 1-3) were also found to be a route for CO formation. Finally, two possible pathways from CH 3 to CO are proposed:(a) CH 3 → CH 2 → CH → CHO → CO;(b) CH 3 → CH 3 O → CH 2 O → CHO → CO.
