Passive jamming is believed to have very good potential in countermeasure community.In this paper,a passive angular blinking jamming method based on electronically controlled corner reflectors is proposed.The amplitud...Passive jamming is believed to have very good potential in countermeasure community.In this paper,a passive angular blinking jamming method based on electronically controlled corner reflectors is proposed.The amplitude of the incident wave can be modulated by switching the corner reflector between the penetration state and the reflection state,and the ensemble of multiple corner reflectors with towing rope can result in complex angle decoying effects.Dependency of the decoying effect on corner reflectors’radar cross section and positions are analyzed and simulated.Results show that the angle measured by a monopulse radar can be significantly interfered by this method while the automatic tracking is employed.展开更多
Spontaneously blinking probe, which switches between dark and bright state without UV or external additives, is extremely attractive in super resolution imaging of live cells. Herein, a clickable rhodamine spirolactam...Spontaneously blinking probe, which switches between dark and bright state without UV or external additives, is extremely attractive in super resolution imaging of live cells. Herein, a clickable rhodamine spirolactam probe, Atto565-Tet, is rationally constructed for spontaneously blinking after biorthogonal labelling and successfully applied to super resolution imaging of mitochondria and lysosomes.展开更多
AIM:To investigate the relationship between dynamic tear meniscus parameters and dry eye using an automated tear meniscus segmentation method.METHODS:The analysis of tear meniscus videos captured within 5s after a com...AIM:To investigate the relationship between dynamic tear meniscus parameters and dry eye using an automated tear meniscus segmentation method.METHODS:The analysis of tear meniscus videos captured within 5s after a complete blink includes data from 38 participates.By processing video data,several key parameters including the average height of the tear meniscus at different lengths,the curvature of the tear meniscus’s upper boundary,and the total area of the tear meniscus in each frame were calculated.The effective values of these dynamic parameters were then linearly fitted to explore the relationship between their changing trends and dry eye disease.RESULTS:In 94.74%of the samples,the average height of central tear meniscus increased over time.Moreover,97.37%of the samples exhibited an increase in the overall tear meniscus height(TMH)and area from the nasal to temporal side.Notably,the central TMH increased at a faster rate compared to the nasal side with the temporal side showing the slowest ascent.Statistical analysis indicates that the upper boundary curvature of the whole tear meniscus as well as the tear meniscus of the nasal side(2,3,and 4 mm)aid in identifying the presence of dry eye and assessing its severity.CONCLUSION:This study contributes to the understanding of tear meniscus dynamics as potential markers for dry eye,utilizing an automated and non-invasive approach that has implications for clinical assessment.展开更多
Super-resolution optical fluctuation imaging is dependent on the blinking frequency of fluorophores.Consequently,improvement of the photoluminescence(PL)blink frequency is important.This is achieved for 3C–SiC nanocr...Super-resolution optical fluctuation imaging is dependent on the blinking frequency of fluorophores.Consequently,improvement of the photoluminescence(PL)blink frequency is important.This is achieved for 3C–SiC nanocrystals(NCs)by simply increasing the excitation power.Using an excitation of 488 nm with powers of 5μW to 50μW,individual 3C–SiC NC always exhibits PL blinking with a short on-state sojourn time(<0.1 s).A fast Fourier transform method is exploited to determine the PL switching frequency.It is found that the frequency of the bright state increases from 2 Hz to 20 Hz as the excitation power increases from 5μW to 50μW,which is explained by the Auger photonionization model.展开更多
Abnormal accumulation of intracellular and extrac-ellularβ-amyloid(Aβ)aggregates is closely related to the pathogenesis of Alzheimer’s disease(AD).In this work,we use quinolinium derivatives with electron-rich anil...Abnormal accumulation of intracellular and extrac-ellularβ-amyloid(Aβ)aggregates is closely related to the pathogenesis of Alzheimer’s disease(AD).In this work,we use quinolinium derivatives with electron-rich aniline substituents as the skeletons to develop a set of spontaneous blinking ffuorophores by the formation of long-lived radicals.These probes can target Aβ_(1−40) aggregates and exhibit strong deep-red emission upon binding to Aβ_(1−40) aggregates.More importantly,at the single-molecule level,these probes display spontaneous blinking,low duty cycle,and high photon output,which are suitable for the nanoscopic imaging of Aβ aggregates in living cells.The assembly process of the Aβ aggregates was then tracked with nanoscopic imaging.The elongation rate on the cell membrane was noticeably fast over that in the solution.This work provides a feasible strategy for the design of spontaneous blinking ffuorophores for Aβ aggregates.展开更多
AIM:To characterize the ocular surface characteristics in the Nepalese population across all age groups who have used digital screens for extended durations over several years.METHODS:In a cross-sectional,observationa...AIM:To characterize the ocular surface characteristics in the Nepalese population across all age groups who have used digital screens for extended durations over several years.METHODS:In a cross-sectional,observational study,144 digital screen users were assessed for dry eye disease(DED)using subjective and objective measures.The Ocular Surface Disease Index(OSDI)Questionnaire evaluated symptoms,followed by clinical assessments,including slit lamp biomicroscopy,tear breakup time(TBUT),Oxford Scheme grading,and Schirmer I test.DED was diagnosed if a patient had an OSDI score over 13 and at least two clinical signs(OSDI,Schirmer I test,or ocular staining).The prevalence of DED was calculated based on the proportion of patients meeting these criteria.RESULTS:Of the 144 participants(mean age:34.6±15.2y),78(54.2%)were female.The use of digital screens varied between 2-8h(mean duration:4.1±2.7h)per day.The mean OSDI score,TBUT score,and the Schirmer I scores were 22.7±10.5(max-min:24.4-20.9),6.8±4.2s(max-min:7.5-6.1),and 12.3±4.6 mm(max-min:13.1-11.5)respectively with 95%confidence interval(β=1.96),and a two-tailed statistical significance level of 5%(α=0.05).With increased screen use,TBUT shortened and OSDI scores increased significantly(P<0.01),though Schirmer I scores were unaffected(P>0.05).The prevalence of DED ranged from 6.3%to 22.9%in those using screens for more than 2h,with an overall prevalence of 67.4%among digital screen users.CONCLUSION:There is a significant association between prolonged use of digital screens and clinical markers of dry eye signs and symptoms.展开更多
The two frequently observed phenomena,photoluminescence(PL)blinking and quantum-confined Stark effect(QCSE)-induced spectral diffusion,are not conducive to the applications of colloidal quantum dots(QDs).It remains el...The two frequently observed phenomena,photoluminescence(PL)blinking and quantum-confined Stark effect(QCSE)-induced spectral diffusion,are not conducive to the applications of colloidal quantum dots(QDs).It remains elusive how these two phenomena are linked to each other.Unraveling the potential link between blinking and QCSE could facilitate the adoption of appropriate strategies that can simultaneously suppress both PL blinking and spectral diffusion.In this work,we investigated the blinking mechanism and QCSE of single CdSe/CdS/ZnS QDs in the presence of positive and negative surface charges using single-dot PL spectroscopy.We found that the negative surface charges can simultaneously suppress PL blinking and spectral diffusion of single QDs.On the other hand,the positive surface charges could change the blinking mechanisms of QDs from Auger-blinking to band-edge carrier(BC)-blinking.Two types of QCSE were observed,and a significant QCSE-induced spectral broadening of 5.25 nm was measured,which could be attributed to the hopping of surface charges between different surface-trap sites.Based on these findings,several theoretical models are proposed to explain various phenomena observed.展开更多
We investigate the issue of synchronizing a blinking coupling mobile agent network through a blinking adaptation strategy,where each agent with blinking wave emission behavior not only adjusts its blinking period acco...We investigate the issue of synchronizing a blinking coupling mobile agent network through a blinking adaptation strategy,where each agent with blinking wave emission behavior not only adjusts its blinking period according to the local property of its neighbors,but also coordinates its blinking phase with those of neighboring agents.In leading the agents to blink orderly with a blinking period commensurate with the characteristic time of the dynamical oscillator,the presented blinking adaptation strategy works effectively in guaranteeing the synchronous motion of the considered network when the power density is large.In addition,the influence of the controlling parameter and moving velocity on network evolution is studied by assessing the convergence time.展开更多
Recent advances in artificial intelligence and the availability of large-scale benchmarks have made deepfake video generation and manipulation easier.Therefore,developing reliable and robust deepfake video detection m...Recent advances in artificial intelligence and the availability of large-scale benchmarks have made deepfake video generation and manipulation easier.Therefore,developing reliable and robust deepfake video detection mechanisms is paramount.This research introduces a novel real-time deepfake video detection framework by analyzing gaze and blink patterns,addressing the spatial-temporal challenges unique to gaze and blink anomalies using the TimeSformer and hybrid Transformer-CNN models.The TimeSformer architecture leverages spatial-temporal attention mechanisms to capture fine-grained blinking intervals and gaze direction anomalies.Compared to state-of-the-art traditional convolutional models like MesoNet and EfficientNet,which primarily focus on global facial features,our approach emphasizes localized eye-region analysis,significantly enhancing detection accuracy.We evaluate our framework on four standard datasets:FaceForensics,CelebDF-V2,DFDC,and FakeAVCeleb.The proposed framework results reveal higher accuracy,with the TimeSformer model achieving accuracies of 97.5%,96.3%,95.8%,and 97.1%,and with the hybrid Transformer-CNN model demonstrating accuracies of 92.8%,91.5%,90.9%,and 93.2%,on FaceForensics,CelebDF-V2,DFDC,and FakeAVCeleb datasets,respectively,showing robustness in distinguishing manipulated from authentic videos.Our research provides a robust state-of-the-art framework for real-time deepfake video detection.This novel study significantly contributes to video forensics,presenting scalable and accurate real-world application solutions.展开更多
Blinking is regarded as the continuous interrupted eyelid closure or opening and its thermal effect will compromise between these two. During a blink, the heat loss via convection, radiation and tear evaporation from ...Blinking is regarded as the continuous interrupted eyelid closure or opening and its thermal effect will compromise between these two. During a blink, the heat loss via convection, radiation and tear evaporation from cornea is prevented, warm tear is lay- ered across corneal surface and the vessels of the palpebral conjunctiva provide heat to anterior eye. In most of the thermal models in human eye that are found in literatures, effect of blinking is not included, simulation is carried out only in open eye. Thus, in this paper, thermal effects of blinking are investigated using one-dimensional finite element method in transient state case. The bio-heat transfer process is simulated during different blinking rates, lid closure and opening. The simulation is carried out using normal and extreme values of ambient temperatures, blood temperatures, evaporation rates, blood perfusion rates, and lens thermal conduetivities. Blinking is found to increase corneal and lens temperature by 1.29℃ and 0.78℃ respectively when compared to open eye. The results obtained from this model are useful in predicting temperature distribution in different laser eye surgeries, hyperthermia and cryosurgery treatment of eyelid carci- noma, choroidal melanoma and can be used for diagnosing temperature-related diseases.展开更多
The photostability of a colloidal single photon emitter in near-infrared regime at room temperature is investigated.The fluorescence lifetime,blinking phenomenon,and anti-bunching effect of a single CdTeSe/ZnS quantum...The photostability of a colloidal single photon emitter in near-infrared regime at room temperature is investigated.The fluorescence lifetime,blinking phenomenon,and anti-bunching effect of a single CdTeSe/ZnS quantum dot with an emission wavelength of 800 nm at room temperature are studied.The second-order correlation function at zero delay time is much smaller than 0.1,which proves that the emission from single quantum dots at 800 nm is a highly pure single-photon source.The effects of the irradiation duration on the fluorescence from single quantum dots are analyzed.The experimental results can be explained by a recombination model including a multi-nonradiative recombination center model and a multi-charged model.展开更多
Facial synkinesis,a sequela of peripheral facial nerve palsy,is characterized by simultaneous involuntary facial movement during a voluntary desired one.Maladaptive cortical plasticity might be involved in the dysfunc...Facial synkinesis,a sequela of peripheral facial nerve palsy,is characterized by simultaneous involuntary facial movement during a voluntary desired one.Maladaptive cortical plasticity might be involved in the dysfunction of facial muscles.This cohort study investigated the cortical functional alterations in patients with unilateral facial synkinesis,using the task functional magnetic resonance imaging.Facial motor tasks,including blinking and smiling,were performed by 16 patients（aged 30.6 ± 4.5 years,14 females/2 males） and 24 age-and sex-matched healthy controls（aged 29.1 ± 4.2 years,19 females/5 males）.Results demonstrated that activation in the cortico-facial motor representation area was lower during tasks in patients with facial synkinesis compared with healthy controls.Facial movements on either side performed by patients caused more intensive activation of the supplementary motor area on the contralateral side of the affected face,than those on the unaffected side.Our results revealed that there was cortical reorganization in the primary sensorimotor area and the supplementary motor area.This study was registered in Chinese Clinical Trial Registry（registration number： Chi CTR1800014630）.展开更多
Objective To investigate the spike activities of cerebellar cortical cells in a computational network model con- structed based on the anatomical structure of cerebellar cortex. Methods and Results The multicompartmen...Objective To investigate the spike activities of cerebellar cortical cells in a computational network model con- structed based on the anatomical structure of cerebellar cortex. Methods and Results The multicompartment model of neuron and NEURON software were used to study the external influences on cerebellar cortical cells. Various potential spike patterns in these cells were obtained. By analyzing the impacts of different incoming stimuli on the potential spike of Purkinje cell, temporal focusing caused by the granule cell-golgi cell feedback inhibitory loop to Purkinje cell and spa- tial focusing caused by the parallel fiber-basket/stellate cell local inhibitory loop to Purkinje cell were discussed. Finally, the motor learning process of rabbit eye blink conditioned reflex was demonstrated in this model. The simulation results showed that when the afferent from climbing fiber existed, rabbit adaptation to eye blinking gradually became stable under the Spike Timing-Dependent Plasticity （STDP） learning rule. Conclusion The constructed cerebellar cortex network is a reliable and feasible model. The model simulation results confirmed the output signal stability of cerebellar cortex after STDP learning and the network can execute the function of spatial and temporal focusing.展开更多
Carbon dots(CDs), because of their unique properties, are being rapidly developed as important luminescent materials for imaging, sensing, and use in photonic devices. However, most of the reported fundamental propert...Carbon dots(CDs), because of their unique properties, are being rapidly developed as important luminescent materials for imaging, sensing, and use in photonic devices. However, most of the reported fundamental properties of the CDs are results of investigations conducted in the solution state, which may be completely different from those conducted in the solid state. In this work, we study the luminescence properties, photostability, and the dynamics of CDs in different matrix environments, from ensemble to the single-particle level. We observed that the properties associated with the emission centers and photostability of CDs were extremely sensitive to the local chemical environment. A better understanding of the dependence of the spectroscopic properties of CDs on the complex local chemical environment is an important step toward finding new ways of controlling the optical properties of CDs and optimizing their use in various applications.展开更多
Bio-based human computer interface (HCI) has attracted more and more attention of researches all over the world in recent years. In this paper, a HCI system which based on electrooculogram (EOG) is proposed. It transf...Bio-based human computer interface (HCI) has attracted more and more attention of researches all over the world in recent years. In this paper, a HCI system which based on electrooculogram (EOG) is proposed. It transforms electrical po-tentials recorded by horizontal and vertical EOG into a computer in order to control external equipment. The system consists of EOG acqui-sition unit, EOG pattern recognition part and control command output unit. Three plane elec-trodes are employed to detect EOG signals, which contain the information related to the eye blinking and vertical (or horizontal) eye move-ments referred to pre-designed command table. An online signal processing algorithm is de-signed to get the command information con-tained in EOG signals, and these commands could be used to control the computer or other instruments. Based on this HCI system, the remote control experiments driven by EOG are realized.展开更多
基金supported by the Equipment Pre-research Project(GK202002A020068)。
文摘Passive jamming is believed to have very good potential in countermeasure community.In this paper,a passive angular blinking jamming method based on electronically controlled corner reflectors is proposed.The amplitude of the incident wave can be modulated by switching the corner reflector between the penetration state and the reflection state,and the ensemble of multiple corner reflectors with towing rope can result in complex angle decoying effects.Dependency of the decoying effect on corner reflectors’radar cross section and positions are analyzed and simulated.Results show that the angle measured by a monopulse radar can be significantly interfered by this method while the automatic tracking is employed.
基金supported by the National Natural Science Foundation of China (Nos. 21421005, 21576040, 21776037, 22004011)China Postdoctoral Science Foundation (Nos. BX20200073 and 2020M670754)Dalian Science and Technology Innovation Fund (No. 2020JJ25CY014)。
文摘Spontaneously blinking probe, which switches between dark and bright state without UV or external additives, is extremely attractive in super resolution imaging of live cells. Herein, a clickable rhodamine spirolactam probe, Atto565-Tet, is rationally constructed for spontaneously blinking after biorthogonal labelling and successfully applied to super resolution imaging of mitochondria and lysosomes.
基金Supported by Medical-Engineering Interdisciplinary Research Foundation of Shenzhen University and Research Development Fund of Beijing Municipal Health Commission(No.2019-4).
文摘AIM:To investigate the relationship between dynamic tear meniscus parameters and dry eye using an automated tear meniscus segmentation method.METHODS:The analysis of tear meniscus videos captured within 5s after a complete blink includes data from 38 participates.By processing video data,several key parameters including the average height of the tear meniscus at different lengths,the curvature of the tear meniscus’s upper boundary,and the total area of the tear meniscus in each frame were calculated.The effective values of these dynamic parameters were then linearly fitted to explore the relationship between their changing trends and dry eye disease.RESULTS:In 94.74%of the samples,the average height of central tear meniscus increased over time.Moreover,97.37%of the samples exhibited an increase in the overall tear meniscus height(TMH)and area from the nasal to temporal side.Notably,the central TMH increased at a faster rate compared to the nasal side with the temporal side showing the slowest ascent.Statistical analysis indicates that the upper boundary curvature of the whole tear meniscus as well as the tear meniscus of the nasal side(2,3,and 4 mm)aid in identifying the presence of dry eye and assessing its severity.CONCLUSION:This study contributes to the understanding of tear meniscus dynamics as potential markers for dry eye,utilizing an automated and non-invasive approach that has implications for clinical assessment.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.11604155,11604147,and 51702379)China Postdoctoral Science Foundation(Grant Nos.2016M600428 and 2017T100386)the Planned Projects for Postdoctoral Research Funds of China(Grant No.1601023A)
文摘Super-resolution optical fluctuation imaging is dependent on the blinking frequency of fluorophores.Consequently,improvement of the photoluminescence(PL)blink frequency is important.This is achieved for 3C–SiC nanocrystals(NCs)by simply increasing the excitation power.Using an excitation of 488 nm with powers of 5μW to 50μW,individual 3C–SiC NC always exhibits PL blinking with a short on-state sojourn time(<0.1 s).A fast Fourier transform method is exploited to determine the PL switching frequency.It is found that the frequency of the bright state increases from 2 Hz to 20 Hz as the excitation power increases from 5μW to 50μW,which is explained by the Auger photonionization model.
基金supported by National Natural Science Foundation of China(NSFC,Project No.22174079,21974073)Natural Science Foundation of Hunan Province(2022JJ40266)the Scientific Research Foundation of Hunan Provincial Education Department(20A299).
文摘Abnormal accumulation of intracellular and extrac-ellularβ-amyloid(Aβ)aggregates is closely related to the pathogenesis of Alzheimer’s disease(AD).In this work,we use quinolinium derivatives with electron-rich aniline substituents as the skeletons to develop a set of spontaneous blinking ffuorophores by the formation of long-lived radicals.These probes can target Aβ_(1−40) aggregates and exhibit strong deep-red emission upon binding to Aβ_(1−40) aggregates.More importantly,at the single-molecule level,these probes display spontaneous blinking,low duty cycle,and high photon output,which are suitable for the nanoscopic imaging of Aβ aggregates in living cells.The assembly process of the Aβ aggregates was then tracked with nanoscopic imaging.The elongation rate on the cell membrane was noticeably fast over that in the solution.This work provides a feasible strategy for the design of spontaneous blinking ffuorophores for Aβ aggregates.
文摘AIM:To characterize the ocular surface characteristics in the Nepalese population across all age groups who have used digital screens for extended durations over several years.METHODS:In a cross-sectional,observational study,144 digital screen users were assessed for dry eye disease(DED)using subjective and objective measures.The Ocular Surface Disease Index(OSDI)Questionnaire evaluated symptoms,followed by clinical assessments,including slit lamp biomicroscopy,tear breakup time(TBUT),Oxford Scheme grading,and Schirmer I test.DED was diagnosed if a patient had an OSDI score over 13 and at least two clinical signs(OSDI,Schirmer I test,or ocular staining).The prevalence of DED was calculated based on the proportion of patients meeting these criteria.RESULTS:Of the 144 participants(mean age:34.6±15.2y),78(54.2%)were female.The use of digital screens varied between 2-8h(mean duration:4.1±2.7h)per day.The mean OSDI score,TBUT score,and the Schirmer I scores were 22.7±10.5(max-min:24.4-20.9),6.8±4.2s(max-min:7.5-6.1),and 12.3±4.6 mm(max-min:13.1-11.5)respectively with 95%confidence interval(β=1.96),and a two-tailed statistical significance level of 5%(α=0.05).With increased screen use,TBUT shortened and OSDI scores increased significantly(P<0.01),though Schirmer I scores were unaffected(P>0.05).The prevalence of DED ranged from 6.3%to 22.9%in those using screens for more than 2h,with an overall prevalence of 67.4%among digital screen users.CONCLUSION:There is a significant association between prolonged use of digital screens and clinical markers of dry eye signs and symptoms.
基金the National Key Research and Development Program of China(No.2017YFA0304203)the National Natural Science Foundation of China(Nos.62127817,62075120,62075122,61875109,91950109,and 62105193),NSFCSTINT(No.62011530133)+3 种基金PCSIRT(No.IRT_17R70)Natural Science Foundation of Shanxi Province(No.201901D111010(ZD))Research Project Supported by Shanxi Scholarship Council of China(No.HGKY2019002)PTIT,Shanxi“1331 Project”,and 111 project(No.D18001).
文摘The two frequently observed phenomena,photoluminescence(PL)blinking and quantum-confined Stark effect(QCSE)-induced spectral diffusion,are not conducive to the applications of colloidal quantum dots(QDs).It remains elusive how these two phenomena are linked to each other.Unraveling the potential link between blinking and QCSE could facilitate the adoption of appropriate strategies that can simultaneously suppress both PL blinking and spectral diffusion.In this work,we investigated the blinking mechanism and QCSE of single CdSe/CdS/ZnS QDs in the presence of positive and negative surface charges using single-dot PL spectroscopy.We found that the negative surface charges can simultaneously suppress PL blinking and spectral diffusion of single QDs.On the other hand,the positive surface charges could change the blinking mechanisms of QDs from Auger-blinking to band-edge carrier(BC)-blinking.Two types of QCSE were observed,and a significant QCSE-induced spectral broadening of 5.25 nm was measured,which could be attributed to the hopping of surface charges between different surface-trap sites.Based on these findings,several theoretical models are proposed to explain various phenomena observed.
基金supported by the National Natural Science Foundation of China (Nos.60736021,61004106,and U0735003)the National High-Tech R & D Program (863) of China (No. 2009AA04Z154)
文摘We investigate the issue of synchronizing a blinking coupling mobile agent network through a blinking adaptation strategy,where each agent with blinking wave emission behavior not only adjusts its blinking period according to the local property of its neighbors,but also coordinates its blinking phase with those of neighboring agents.In leading the agents to blink orderly with a blinking period commensurate with the characteristic time of the dynamical oscillator,the presented blinking adaptation strategy works effectively in guaranteeing the synchronous motion of the considered network when the power density is large.In addition,the influence of the controlling parameter and moving velocity on network evolution is studied by assessing the convergence time.
文摘Recent advances in artificial intelligence and the availability of large-scale benchmarks have made deepfake video generation and manipulation easier.Therefore,developing reliable and robust deepfake video detection mechanisms is paramount.This research introduces a novel real-time deepfake video detection framework by analyzing gaze and blink patterns,addressing the spatial-temporal challenges unique to gaze and blink anomalies using the TimeSformer and hybrid Transformer-CNN models.The TimeSformer architecture leverages spatial-temporal attention mechanisms to capture fine-grained blinking intervals and gaze direction anomalies.Compared to state-of-the-art traditional convolutional models like MesoNet and EfficientNet,which primarily focus on global facial features,our approach emphasizes localized eye-region analysis,significantly enhancing detection accuracy.We evaluate our framework on four standard datasets:FaceForensics,CelebDF-V2,DFDC,and FakeAVCeleb.The proposed framework results reveal higher accuracy,with the TimeSformer model achieving accuracies of 97.5%,96.3%,95.8%,and 97.1%,and with the hybrid Transformer-CNN model demonstrating accuracies of 92.8%,91.5%,90.9%,and 93.2%,on FaceForensics,CelebDF-V2,DFDC,and FakeAVCeleb datasets,respectively,showing robustness in distinguishing manipulated from authentic videos.Our research provides a robust state-of-the-art framework for real-time deepfake video detection.This novel study significantly contributes to video forensics,presenting scalable and accurate real-world application solutions.
文摘Blinking is regarded as the continuous interrupted eyelid closure or opening and its thermal effect will compromise between these two. During a blink, the heat loss via convection, radiation and tear evaporation from cornea is prevented, warm tear is lay- ered across corneal surface and the vessels of the palpebral conjunctiva provide heat to anterior eye. In most of the thermal models in human eye that are found in literatures, effect of blinking is not included, simulation is carried out only in open eye. Thus, in this paper, thermal effects of blinking are investigated using one-dimensional finite element method in transient state case. The bio-heat transfer process is simulated during different blinking rates, lid closure and opening. The simulation is carried out using normal and extreme values of ambient temperatures, blood temperatures, evaporation rates, blood perfusion rates, and lens thermal conduetivities. Blinking is found to increase corneal and lens temperature by 1.29℃ and 0.78℃ respectively when compared to open eye. The results obtained from this model are useful in predicting temperature distribution in different laser eye surgeries, hyperthermia and cryosurgery treatment of eyelid carci- noma, choroidal melanoma and can be used for diagnosing temperature-related diseases.
基金Project supported by the National Natural Science Foundation of China(Grant No.92165202)the Innovation Program for Quantum Science and Technology,China(Grant No.2021ZD0300701)the Strategic Priority Research Program(A)of Chinese Academy of Sciences(Grant No.XDA18040300).
文摘The photostability of a colloidal single photon emitter in near-infrared regime at room temperature is investigated.The fluorescence lifetime,blinking phenomenon,and anti-bunching effect of a single CdTeSe/ZnS quantum dot with an emission wavelength of 800 nm at room temperature are studied.The second-order correlation function at zero delay time is much smaller than 0.1,which proves that the emission from single quantum dots at 800 nm is a highly pure single-photon source.The effects of the irradiation duration on the fluorescence from single quantum dots are analyzed.The experimental results can be explained by a recombination model including a multi-nonradiative recombination center model and a multi-charged model.
基金supported by the Youth Researcher Foundation of Shanghai Municipal Commission of Health and Family Planning,No.20144Y0095
文摘Facial synkinesis,a sequela of peripheral facial nerve palsy,is characterized by simultaneous involuntary facial movement during a voluntary desired one.Maladaptive cortical plasticity might be involved in the dysfunction of facial muscles.This cohort study investigated the cortical functional alterations in patients with unilateral facial synkinesis,using the task functional magnetic resonance imaging.Facial motor tasks,including blinking and smiling,were performed by 16 patients（aged 30.6 ± 4.5 years,14 females/2 males） and 24 age-and sex-matched healthy controls（aged 29.1 ± 4.2 years,19 females/5 males）.Results demonstrated that activation in the cortico-facial motor representation area was lower during tasks in patients with facial synkinesis compared with healthy controls.Facial movements on either side performed by patients caused more intensive activation of the supplementary motor area on the contralateral side of the affected face,than those on the unaffected side.Our results revealed that there was cortical reorganization in the primary sensorimotor area and the supplementary motor area.This study was registered in Chinese Clinical Trial Registry（registration number： Chi CTR1800014630）.
基金supported by the grants from National Natural Science Foundation of China (No. 10872069)
文摘Objective To investigate the spike activities of cerebellar cortical cells in a computational network model con- structed based on the anatomical structure of cerebellar cortex. Methods and Results The multicompartment model of neuron and NEURON software were used to study the external influences on cerebellar cortical cells. Various potential spike patterns in these cells were obtained. By analyzing the impacts of different incoming stimuli on the potential spike of Purkinje cell, temporal focusing caused by the granule cell-golgi cell feedback inhibitory loop to Purkinje cell and spa- tial focusing caused by the parallel fiber-basket/stellate cell local inhibitory loop to Purkinje cell were discussed. Finally, the motor learning process of rabbit eye blink conditioned reflex was demonstrated in this model. The simulation results showed that when the afferent from climbing fiber existed, rabbit adaptation to eye blinking gradually became stable under the Spike Timing-Dependent Plasticity （STDP） learning rule. Conclusion The constructed cerebellar cortex network is a reliable and feasible model. The model simulation results confirmed the output signal stability of cerebellar cortex after STDP learning and the network can execute the function of spatial and temporal focusing.
基金financial support from National Natural Science Foundation of China (No.22073046)Fundamental Research Funds for the Central Universities。
文摘Carbon dots(CDs), because of their unique properties, are being rapidly developed as important luminescent materials for imaging, sensing, and use in photonic devices. However, most of the reported fundamental properties of the CDs are results of investigations conducted in the solution state, which may be completely different from those conducted in the solid state. In this work, we study the luminescence properties, photostability, and the dynamics of CDs in different matrix environments, from ensemble to the single-particle level. We observed that the properties associated with the emission centers and photostability of CDs were extremely sensitive to the local chemical environment. A better understanding of the dependence of the spectroscopic properties of CDs on the complex local chemical environment is an important step toward finding new ways of controlling the optical properties of CDs and optimizing their use in various applications.
文摘Bio-based human computer interface (HCI) has attracted more and more attention of researches all over the world in recent years. In this paper, a HCI system which based on electrooculogram (EOG) is proposed. It transforms electrical po-tentials recorded by horizontal and vertical EOG into a computer in order to control external equipment. The system consists of EOG acqui-sition unit, EOG pattern recognition part and control command output unit. Three plane elec-trodes are employed to detect EOG signals, which contain the information related to the eye blinking and vertical (or horizontal) eye move-ments referred to pre-designed command table. An online signal processing algorithm is de-signed to get the command information con-tained in EOG signals, and these commands could be used to control the computer or other instruments. Based on this HCI system, the remote control experiments driven by EOG are realized.
