Bioelectronics have gained substantial research attention owing to their potential applications in health monitoring and diagnose,and greatly promoted the development of biomedicine.Recently,poly(3,4-ethylenedioxythio...Bioelectronics have gained substantial research attention owing to their potential applications in health monitoring and diagnose,and greatly promoted the development of biomedicine.Recently,poly(3,4-ethylenedioxythiophene):polystyrene sulfonate(PEDOT:PSS)hydrogels have arose as a promising candi-date for the next-generation bioelectronic interface due to its high-conductivity,versatility,flexibility and biocompatibility.In this review,we highlight the recent advances of PEDOT:PSS hydrogels,including the gelation methods and modification strategies,and summarize their wide applications in different type of sensors and tissue engineering in detail.We expect that this work will provide valuable information regarding the functionalizations and applications of PEDOT:PSS hydrogels.展开更多
Generation of magnetic micrbubbles and their basic magnetic and acoustic mechanism are reviewed. The ultrasound （US） and magnetic resonance （MR） dual imaging, the controlled therapeutic delivery, as well as theran...Generation of magnetic micrbubbles and their basic magnetic and acoustic mechanism are reviewed. The ultrasound （US） and magnetic resonance （MR） dual imaging, the controlled therapeutic delivery, as well as theranostic multifunctions are all introduced based on recent research results. Some on-going research is also discussed.展开更多
Self-assembly processes are ubiquitous in biological systems,playing essential roles in sustaining life activities.The exploration of self-assembled biomaterials(SABMs)holds great potential for advancing various field...Self-assembly processes are ubiquitous in biological systems,playing essential roles in sustaining life activities.The exploration of self-assembled biomaterials(SABMs)holds great potential for advancing various fields,particularly in biomedicine and materials science.Because of the unique reversibility and responsiveness to stimuli,dynamic covalent bonds(DCBs)and noncovalent bonds(NCBs)endow SABMs with self-healing properties,stimuli responsiveness and controllable degradation,making them highly versatile for a wide range of biomedical applications.In this article,recent advances and future trends for SABMs based on DCBs and NCBs are thoroughly reviewed.We begin by introducing the molecular principles and characteristics of DCBs and NCBs that govern the formation of SABMs.We also explore the responsive and functional features of these materials in detail.Finally,we summarize the perspectives and challenges associated with the development of SABMs in biomedical applications.We aim for this review to offer a comprehensive overview of SABMs,serving as a valuable resource for chemists and materials scientists striving to further advance the design of SABMs in biological applications.展开更多
基金National Natural Science Foundation of China (No. 82272120)Natural Science Foundation of Zhejiang Province, China (Nos. LQ20F010011, LY18H180006)+2 种基金Key Research and Development Program of Zhejiang Province, China (No. 2022C03002)supported by MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Zhejiang University (No. 2022MSF**)the open research fund of Guangdong Provincial Key Laboratory of Advanced Biomaterials.
文摘Bioelectronics have gained substantial research attention owing to their potential applications in health monitoring and diagnose,and greatly promoted the development of biomedicine.Recently,poly(3,4-ethylenedioxythiophene):polystyrene sulfonate(PEDOT:PSS)hydrogels have arose as a promising candi-date for the next-generation bioelectronic interface due to its high-conductivity,versatility,flexibility and biocompatibility.In this review,we highlight the recent advances of PEDOT:PSS hydrogels,including the gelation methods and modification strategies,and summarize their wide applications in different type of sensors and tissue engineering in detail.We expect that this work will provide valuable information regarding the functionalizations and applications of PEDOT:PSS hydrogels.
基金Project supported by the National Basic Research Program of China (Grant Nos.2011CB933503 and 2013CB733804)the National Natural Science Foundation of China (Grant No.31000453)the Fundamental Research Funds for Central Universities (Grant No.2013CB733804)
文摘Generation of magnetic micrbubbles and their basic magnetic and acoustic mechanism are reviewed. The ultrasound （US） and magnetic resonance （MR） dual imaging, the controlled therapeutic delivery, as well as theranostic multifunctions are all introduced based on recent research results. Some on-going research is also discussed.
基金supported by the National Natural Science Foundation of China(Nos.22405212 and 22471219)the Shaanxi Fundamental Science Research Project for Chemistry&Biology(23JHZ002).
文摘Self-assembly processes are ubiquitous in biological systems,playing essential roles in sustaining life activities.The exploration of self-assembled biomaterials(SABMs)holds great potential for advancing various fields,particularly in biomedicine and materials science.Because of the unique reversibility and responsiveness to stimuli,dynamic covalent bonds(DCBs)and noncovalent bonds(NCBs)endow SABMs with self-healing properties,stimuli responsiveness and controllable degradation,making them highly versatile for a wide range of biomedical applications.In this article,recent advances and future trends for SABMs based on DCBs and NCBs are thoroughly reviewed.We begin by introducing the molecular principles and characteristics of DCBs and NCBs that govern the formation of SABMs.We also explore the responsive and functional features of these materials in detail.Finally,we summarize the perspectives and challenges associated with the development of SABMs in biomedical applications.We aim for this review to offer a comprehensive overview of SABMs,serving as a valuable resource for chemists and materials scientists striving to further advance the design of SABMs in biological applications.
