All-optically controlled artificial synapses for neuromorphic vision offer unique advantages in simplifying circuit design and minimizing power consumption,meeting the application demands of the current artificial int...All-optically controlled artificial synapses for neuromorphic vision offer unique advantages in simplifying circuit design and minimizing power consumption,meeting the application demands of the current artificial intelligence era.However,developing all-optically controlled devices that combine high performance and high reproducibility remains a significant challenge.In this work,we demonstrate an all-optically controlled artificial synapse based on ZnO and Cs_(2)CoCl_(4)single crystal connected structure,which integrates light information sensing and processing capabilities.Relying on the simple series-connected structure,as well as the positive photoconductance of ZnO and the negative photoconductance of Cs_(2)CoCl_(4),the optically controlled bidirectional synaptic plasticity is realized under ultraviolet and visible light stimulation without additional voltage modulation in the all-optically controlled synapse.In addition,leveraging its ultraviolet-enhanced feature extraction and visible-suppression capabilities,the all-optically controlled synapse can act as denoising units in bioinformation preprocessing and weight-updating units in feature recognition.The proposed all-optically controlled synapses exhibit excellent information perception,low-level noise reduction,and high-level cognition functions for bioinformation recognition under complex light conditions.We believe that this work can provide structural-level insights and inspirations in the design and fabrication of all-optically controlled synapses to promote the application for efficient neuromorphic vision in the future.展开更多
The Beijing Institute of Genomics(BIG)of the Chinese Academy of Sciences,as the leading Institute in Genomics,has walked through 20 year’s journey since being founded in November 2003.From participating in the Human ...The Beijing Institute of Genomics(BIG)of the Chinese Academy of Sciences,as the leading Institute in Genomics,has walked through 20 year’s journey since being founded in November 2003.From participating in the Human Genome Project(HGP)in completing the“1%task”to independently accomplishing the super-hybrid rice genome and other several national and international genome projects,BIG has made tremendous contributions in genomics research and development in China.In 2024,bearing great ambition and responsibility,BIG is transformed to the China National Center for Bioinformation(CNCB),aiming to become a global hub in bioinformatics big data services,innovation,and entrepreneurship.With the completion of its new infrastructure in 2027,CNCB is looking into a brighter future.展开更多
[Objectives]This study was conducted to improve crop yield and select excellent wheat varieties.[Methods]Wheat seedlings were treated with different concentrations of NaCl solution,and the activities of superoxide dis...[Objectives]This study was conducted to improve crop yield and select excellent wheat varieties.[Methods]Wheat seedlings were treated with different concentrations of NaCl solution,and the activities of superoxide dismutase(SOD)and peroxidase(POD)and the content changes of malondialdehyde(MDA)in the leaves of seedlings were determined.A control group(distilled water)and three treatment groups(NaCl concentrations of 1,2 and 3 mmol/L)were set up.When the wheat seedlings grew to two leaves and one heart,they should be treated with different concentrations of NaCl solution(the wheat seedlings grew uniformly,and 20 ml of each NaCl concentration was used for treatment of wheat).When the wheat seedlings grew to four leaves and one heart under stress,samples were taken separately,once every 2 d,for three times,with 5 g of leaves each time.The SOD and POD activities and MDA content of seedlings in the control group and treatment groups were determined,and related protein sequences were analyzed by bioinformatics,including signal peptide prediction,transmembrane domain prediction,phosphorylation prediction and protein structure prediction.[Results]Under NaCl stress,the growth rates of seedling length and root length of wheat decreased obviously,and SOD and POD in leaves decreased,while the MDA content in leaves after treatment increased compared with the control group.SOD had no signal peptide,while POD had signal peptides and a transmembrane region.SOD and POD were different in terms of secondary and tertiary structures and the number of phosphorylation sites.[Conclusions]These results lays a solid theoretical foundation and application prospect for the study on salt tolerance mechanism of wheat seedlings in the later stage.展开更多
The accumulation of the large amount of biological data concerning with gene and protein research has proposed that it is necessary to abstract the biological significance from these data. Then the bioinformatics, equ...The accumulation of the large amount of biological data concerning with gene and protein research has proposed that it is necessary to abstract the biological significance from these data. Then the bioinformatics, equipped with the most advanced computational techniques and supported by the latest biological research, has emerged for this purpose. Some recent information on the developing bioinformatics, associated with the uniform resource location addresses of those available resource sites that support hyper-text or general file transfer proto-展开更多
基金supported by the National Natural Science Foundation of China(nos.62461160330,62304021,and 62404018)the Hebei Natural Science Foundation(F2024105006),the China Postdoctoral Science Foundation(2024T171120 and 2023M740232)the Postdoctoral Fellowship Program of China Postdoctoral Science Foundation(CPSF)(GZB20230932).
文摘All-optically controlled artificial synapses for neuromorphic vision offer unique advantages in simplifying circuit design and minimizing power consumption,meeting the application demands of the current artificial intelligence era.However,developing all-optically controlled devices that combine high performance and high reproducibility remains a significant challenge.In this work,we demonstrate an all-optically controlled artificial synapse based on ZnO and Cs_(2)CoCl_(4)single crystal connected structure,which integrates light information sensing and processing capabilities.Relying on the simple series-connected structure,as well as the positive photoconductance of ZnO and the negative photoconductance of Cs_(2)CoCl_(4),the optically controlled bidirectional synaptic plasticity is realized under ultraviolet and visible light stimulation without additional voltage modulation in the all-optically controlled synapse.In addition,leveraging its ultraviolet-enhanced feature extraction and visible-suppression capabilities,the all-optically controlled synapse can act as denoising units in bioinformation preprocessing and weight-updating units in feature recognition.The proposed all-optically controlled synapses exhibit excellent information perception,low-level noise reduction,and high-level cognition functions for bioinformation recognition under complex light conditions.We believe that this work can provide structural-level insights and inspirations in the design and fabrication of all-optically controlled synapses to promote the application for efficient neuromorphic vision in the future.
文摘The Beijing Institute of Genomics(BIG)of the Chinese Academy of Sciences,as the leading Institute in Genomics,has walked through 20 year’s journey since being founded in November 2003.From participating in the Human Genome Project(HGP)in completing the“1%task”to independently accomplishing the super-hybrid rice genome and other several national and international genome projects,BIG has made tremendous contributions in genomics research and development in China.In 2024,bearing great ambition and responsibility,BIG is transformed to the China National Center for Bioinformation(CNCB),aiming to become a global hub in bioinformatics big data services,innovation,and entrepreneurship.With the completion of its new infrastructure in 2027,CNCB is looking into a brighter future.
文摘[Objectives]This study was conducted to improve crop yield and select excellent wheat varieties.[Methods]Wheat seedlings were treated with different concentrations of NaCl solution,and the activities of superoxide dismutase(SOD)and peroxidase(POD)and the content changes of malondialdehyde(MDA)in the leaves of seedlings were determined.A control group(distilled water)and three treatment groups(NaCl concentrations of 1,2 and 3 mmol/L)were set up.When the wheat seedlings grew to two leaves and one heart,they should be treated with different concentrations of NaCl solution(the wheat seedlings grew uniformly,and 20 ml of each NaCl concentration was used for treatment of wheat).When the wheat seedlings grew to four leaves and one heart under stress,samples were taken separately,once every 2 d,for three times,with 5 g of leaves each time.The SOD and POD activities and MDA content of seedlings in the control group and treatment groups were determined,and related protein sequences were analyzed by bioinformatics,including signal peptide prediction,transmembrane domain prediction,phosphorylation prediction and protein structure prediction.[Results]Under NaCl stress,the growth rates of seedling length and root length of wheat decreased obviously,and SOD and POD in leaves decreased,while the MDA content in leaves after treatment increased compared with the control group.SOD had no signal peptide,while POD had signal peptides and a transmembrane region.SOD and POD were different in terms of secondary and tertiary structures and the number of phosphorylation sites.[Conclusions]These results lays a solid theoretical foundation and application prospect for the study on salt tolerance mechanism of wheat seedlings in the later stage.
文摘The accumulation of the large amount of biological data concerning with gene and protein research has proposed that it is necessary to abstract the biological significance from these data. Then the bioinformatics, equipped with the most advanced computational techniques and supported by the latest biological research, has emerged for this purpose. Some recent information on the developing bioinformatics, associated with the uniform resource location addresses of those available resource sites that support hyper-text or general file transfer proto-
