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Residues important to the allosteric regulation on ligand binding affinity in β3 integrins
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作者 Jizhong Lou1,Wei Chen2,Mei-Yin Chou3,Cheng Zhu1,2,3,4(1Parker H.Petit Institute for Bioengineering and Bioscience,2Woodruff School of Mechanical Engineering,and 3School of Physics,4Coulter Department of Biomedical Engineering,,Georgia Institute of Technology,GA,USA) 《医用生物力学》 EI CAS CSCD 2009年第S1期20-20,共1页
Integrins are heterodimers that mediate cell adhesion and transduce signals bidirectionally across the cell membrane.Integrins often exist in low affinity(or inactive) states for
关键词 Residues important to the allosteric regulation on ligand binding affinity in
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Insights into the regulation of C-repeat binding factors in plant cold signaling 被引量:51
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作者 Jingyan Liu Yiting Shi Shuhua Yang 《Journal of Integrative Plant Biology》 SCIE CAS CSCD 2018年第9期780-795,共16页
Cold temperatures, a major abiotic stress, threaten the growth and development of plants, worldwide. To cope with this adverse environmental cue, plants from temperate climates have evolved an array of sophisticated m... Cold temperatures, a major abiotic stress, threaten the growth and development of plants, worldwide. To cope with this adverse environmental cue, plants from temperate climates have evolved an array of sophisticated mechanisms to acclimate to cold periods, increasing their ability to tolerate freezing stress. Over the last decade, significant progress has been made in determining the molecular mechanisms underpinning cold acclimation, including following the identification of several pivotal components, including candidates for cold sensors, protein kinases, and transcription factors. With these developments, we have a better understanding of the CBF-dependent cold-signaling pathway. In this review, we summarize recent progress made in elucidating the cold-signaling pathways, especially the C-repeat binding factor-dependent pathway, and describe the regulatory function of the crucial components of plant cold signaling. We also discuss the unsolved questions that should be the focus of future work. 展开更多
关键词 Insights into the regulation of C-repeat binding factors in plant cold signaling ICE FLC
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