[目的]研究激素性股骨头坏死(steroid-induced avascular necrosis of the femoral head,SANFH)动物模型的建立方法。[方法]将20只雄性Wistar大鼠随机分为空白对照组、模型组。采用甲基强地松龙联合大肠杆菌内毒素的方法诱导造成SANFH,...[目的]研究激素性股骨头坏死(steroid-induced avascular necrosis of the femoral head,SANFH)动物模型的建立方法。[方法]将20只雄性Wistar大鼠随机分为空白对照组、模型组。采用甲基强地松龙联合大肠杆菌内毒素的方法诱导造成SANFH,对大鼠行为学观察6周后对其进行开场试验、自主活动水迷宫实验和抓力等行为学检测。[结果]与正常组相比,模型组大鼠在开场试验中的运动总距离明显减少,自主活动次数减少,在Morris水迷宫实验中平均速度减小,总活动距离延长,抓力显著降低。[结论]两组大鼠在行为学的改变,证明了甲基强地松龙联合大肠杆菌内毒素成功诱导SANFH大鼠模型,适用于SANFH的发病机制和治疗方法的进一步研究。展开更多
The process of children language acquisition and relevant influence factors has attracted researchers and academician's attention due to its implications for speech therapy and neurolinguistics.The process of chil...The process of children language acquisition and relevant influence factors has attracted researchers and academician's attention due to its implications for speech therapy and neurolinguistics.The process of children's first language acquisition is a dynamic and complicated experience that involves multiple stages.This review examines these stages while considering the impact of language environment.Furthermore,it compares and contrasts research findings on children raised in monolingual and multilingual environments to analyze key influencing factors.The findings suggest that the multilingual environment is shaping the better cognitive and social-interactional development for kids,which make their language performance outstanding compared with monolingual kids.For filling the research gap in this region,the discussion part of this review explored the relationship between linguistic learning and Socioeconomic Status(SES).This paper also underscores a high SES background is having a positive impact on kid's language development.This study focused on the background and psychological factors during language acquisition,which provide meaningful reference for further research in this field.展开更多
文摘[目的]研究激素性股骨头坏死(steroid-induced avascular necrosis of the femoral head,SANFH)动物模型的建立方法。[方法]将20只雄性Wistar大鼠随机分为空白对照组、模型组。采用甲基强地松龙联合大肠杆菌内毒素的方法诱导造成SANFH,对大鼠行为学观察6周后对其进行开场试验、自主活动水迷宫实验和抓力等行为学检测。[结果]与正常组相比,模型组大鼠在开场试验中的运动总距离明显减少,自主活动次数减少,在Morris水迷宫实验中平均速度减小,总活动距离延长,抓力显著降低。[结论]两组大鼠在行为学的改变,证明了甲基强地松龙联合大肠杆菌内毒素成功诱导SANFH大鼠模型,适用于SANFH的发病机制和治疗方法的进一步研究。
文摘The process of children language acquisition and relevant influence factors has attracted researchers and academician's attention due to its implications for speech therapy and neurolinguistics.The process of children's first language acquisition is a dynamic and complicated experience that involves multiple stages.This review examines these stages while considering the impact of language environment.Furthermore,it compares and contrasts research findings on children raised in monolingual and multilingual environments to analyze key influencing factors.The findings suggest that the multilingual environment is shaping the better cognitive and social-interactional development for kids,which make their language performance outstanding compared with monolingual kids.For filling the research gap in this region,the discussion part of this review explored the relationship between linguistic learning and Socioeconomic Status(SES).This paper also underscores a high SES background is having a positive impact on kid's language development.This study focused on the background and psychological factors during language acquisition,which provide meaningful reference for further research in this field.
