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Effects of Short-Term Forest Bathing on Human Health in a Broad-Leaved Evergreen Forest in Zhejiang Province,China 被引量:23
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作者 MAO Gen Xiang LAN Xiao Guang +7 位作者 CAO Yong Bao CHEN Zhuo Mei HE Zhi Huat LV Yuan Dong WANG Ya Zhen HU Xi Lian WANG Guo Fu YAN Jing 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2012年第3期317-324,共8页
Objective To investigate the effects of short-term forest bathing on human health. Methods Twenty healthy male university students participated as subjects and were randomly divided into two groups of 10. One group wa... Objective To investigate the effects of short-term forest bathing on human health. Methods Twenty healthy male university students participated as subjects and were randomly divided into two groups of 10. One group was sent on a two-night trip to a broad-leaved evergreen forest, and the other was sent to a city area. Serum cytokine levels reflecting inflammatory and stress response, indicators reflecting oxidative stress, the distribution of leukocyte subsets, and plasma endothelin-1 (ET-1) concentrations were measured before and after the experiment to evaluate the positive health effects of forest environments. A profile of mood states (POMS) evaluation was used to assess changes in mood states. Results No significant differences in the baseline values of the indicators were observed between the two groups before the experiment. Subjects exposed to the forest environment showed reduced oxidative stress and pro-inflammatory level, as evidenced by decreased malondialdehyde, interleukin-6, and tumor necrosis factor a levels compared with the urban group. Serum cortisol levels were also lower than in the urban group. Notably, the concentration of plasma ET-1 was much lower in subjects exposed to the forest environment. The POMS evaluation showed that after exposure to the forest environment, subjects had lower scores in the negative subscales, and the score for vigor was increased. Conclusion Forest bathing is beneficial to human health, perhaps through preventive effects related to several pathological factors. 展开更多
关键词 Forest bathing Oxidative stress Inflammation ENDOTHELIN-1 Cortisol level
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Additive Benefits of Twice Forest Bathing Trips in Elderly Patients with Chronic Heart Failure 被引量:18
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作者 MAO Gen Xiang CAO Yong Bao +8 位作者 YANG Yan CHEN Zhuo Mei DONG Jian Hua CHEN Sha Sha WU Qing LYU Xiao Ling JIA Bing Bing YAN Jing WANG Guo Fu 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2018年第2期159-162,共4页
Chronic heart failure (CHF), a clinical syndrome resulting from the consequences of various cardiovascular diseases (CVDs), is increasingly becoming a global cause of morbidity and mortality. We had earlier demons... Chronic heart failure (CHF), a clinical syndrome resulting from the consequences of various cardiovascular diseases (CVDs), is increasingly becoming a global cause of morbidity and mortality. We had earlier demonstrated that a 4-day forest bathing trip can provide an adjunctive therapeutic influence on patients with CHF. To further investigate the duration of the impact and the optimal frequency of forest bathing trips in patients with CHF, we recruited those subjects who had experienced the first forest bathing trip again after 4 weeks and randomly categorized them into two groups, namely, the urban control group (city) and the forest bathing group (forest). After a second 4-day forest bathing trip, we observed a steady decline in the brain natriuretic peptide levels, a biomarker of heart failure, and an attenuated inflammatory response as well as oxidative stress. Thus, this exploratory study demonstrated the additive benefits of twice forest bathing trips in elderly patients with CHF, which could further pave the way for analyzing the effects of such interventions in CVDs. 展开更多
关键词 CHF Additive Benefits of Twice Forest bathing Trips in Elderly Patients with Chronic Heart Failure BNP
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Health Effect of Forest Bathing Trip on Elderly Patients with Chronic Obstructive Pulmonary Disease 被引量:18
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作者 JIA Bing Bing YANG Zhou Xin +6 位作者 MAO Gen Xiang LYU Yuan Dong WEN Xiao Lin XU Wei Hong LYU XIAO Ling CAO Yong Bao WANG Guo Fu 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2016年第3期212-218,共7页
Forest bathing trip is a short, leisurely visit to forest. In this study we determined the health effects of forest bathing trip on elderly patients with chronic obstructive pulmonary disease (COPD). The patients we... Forest bathing trip is a short, leisurely visit to forest. In this study we determined the health effects of forest bathing trip on elderly patients with chronic obstructive pulmonary disease (COPD). The patients were randomly divided into two groups. One group was sent to forest, and the other was sent to an urban area as control. Flow cytometry, ELISA, and profile of mood states (POMS) evaluation were performed. In the forest group, 展开更多
关键词 COPD Health Effect of Forest bathing Trip on Elderly Patients with Chronic Obstructive Pulmonary Disease
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Tsunami hazard and mitigation analysis for bathing beaches in China based on numerical simulations
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作者 Jingming Hou Wei Lu +1 位作者 Tingting Fan Peitao Wang 《Acta Oceanologica Sinica》 SCIE CAS CSCD 2022年第12期27-37,共11页
Bathing beaches are usually the first to suffer disasters when tsunamis occur,owing to their proximity to the sea.Several large seismic fault zones are located off the coast of China.The impact of each tsunami scenari... Bathing beaches are usually the first to suffer disasters when tsunamis occur,owing to their proximity to the sea.Several large seismic fault zones are located off the coast of China.The impact of each tsunami scenario on Chinese bathing beaches is different.In this study,numerical models of the worst tsunami scenarios associated with seismic fault zones were considered to assess the tsunami hazard of bathing beaches in China.Numerical results show that tsunami waves from the Pacific Ocean could affect the East China Sea coast through gaps between the Ryukyu Islands.The Zhejiang and Shanghai coasts would be threatened by a tsunami from Ryukyu Trench,and the coasts of Hainan and Guangdong provinces would be threatened by a tsunami from the Manila Trench.The tsunami hazard associated with the Philippine Trench scenario needs particular attention.Owing to China’s offshore topography,the sequential order of tsunami arrival times to coastal provinces in several tsunami scenarios is almost the same.According to the tsunami hazard analysis results,Yalongwan Beach and eight other bathing beaches are at the highest hazard level.A high-resolution numerical calculation model was established to analyze the tsunami physical characteristics for the high-risk bathing beaches.To explore mitigating effects of a tsunami disaster,this study simulated tsunami propagation with the addition of seawalls.The experimental results show that the tsunami prevention seawalls constructed in an appropriate shallow water location have some effect on reducing tsunami hazard.Seawalls separated by a certain distance work even better.The analysis results can provide a scientific reference for subsequent preventive measures such as facility construction and evacuation. 展开更多
关键词 TSUNAMI bathing beach HAZARD MITIGATION
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A Change in Bathing Style May Improve Mental Fitness
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作者 Takaaki Kubo Tomonori Yasuda +6 位作者 Yoshihisa Masumitsu Yoshihiro Iwashita Satoshi Watanabe Taichi Ishizawa Mitsuo Tsunakawa Shingo Yano Junichi Iimaya 《Health》 2015年第2期270-278,共9页
Frequent bathtub bathing (BB) improves the mental health of middle-aged and older Japanese in-dividuals. This study investigated the chronic mental health effects of BB, maintaining warmth using an insulating sheet an... Frequent bathtub bathing (BB) improves the mental health of middle-aged and older Japanese in-dividuals. This study investigated the chronic mental health effects of BB, maintaining warmth using an insulating sheet and sleeping bag after bathtub bathing (BBW), and bathtub bathing with herbal extracts (BBH) in healthy young adults. The study involved healthy young adults who habitually showered, as opposed to bathing. In the first experiment, 18 participants were randomly assigned to either the BB or BBW groups for 14 consecutive nights. After a 2-week washout period, the participants were asked to switch their bathing styles (a cross-over design). In the second experiment, 20 participants were randomly assigned to the BB or BBH group. The herbal extracts for the BBH group contained angelicae radix, aurantii nobilis pericarpium, chamomile, and zingiberis rhizoma. After a 2-week washout period, these participants also switched to the other bathing style. The participants’ mental conditions pre- and post-intervention were assessed using the Profile of Mood States-Brief Form questionnaire, Japanese version, and were statistically analyzed. The participants’ Anger-Hostility score converged to an average (50 points) in the post-BBW and post-BBH participants, and there were no significant differences in BB. The Confusion change rate was significantly different in the first experiment (BB versus BBW). The Depression-Dejection and Fatigue change rates were significantly different in the second experiment (BB versus BBH). Our findings suggest that changing bathing style from showering to BBW or BBH improves the POMS Anger-Hostility scores of healthy young adults. 展开更多
关键词 BATHTUB bathing WARMTH HERBAL Extracts MENTAL FITNESS Healthy Young Adults
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Traditional Japanese Style Bathing May Contribute to Good Health and Longevity
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作者 Mayumi Watanabe Shigeharu Koboshi +3 位作者 Hiroshi Yoshimoto Kazuhiro Kobayashi Chikako Tomiyama Toru Abo 《Health》 CAS 2016年第8期756-763,共8页
The objective of this study was to determine how traditional Japanese style bathing could promote good health. Using healthy volunteers, we assessed body temperature (core and cutaneous), red blood cells, white blood ... The objective of this study was to determine how traditional Japanese style bathing could promote good health. Using healthy volunteers, we assessed body temperature (core and cutaneous), red blood cells, white blood cells (WBCs), venous blood gas parameters (PO2, SO2, PCO2, TCO2, HCO3, and pH), weight loss (which may indicate sweat volume), and the time until sweating before and after bathing. We simultaneously conducted a double-blind clinical trial using a bath additive group and a control group to investigate the effect of a bath additive on the same parameters. We found that bathing increased the core and cutaneous body temperature, as well as PO2, SO2, and blood pH. All of the subjects also showed increases in heart rate and weight loss (sweat volume). After bathing, the number and ratio of granulocytes increased while the number and ratio of lymphocytes decreased. These results tended to be emphasized in the bath additive group;however, significant between-group differences were not detected. Our results indicated that bathing improved blood circulation and had a modulatory effect on the autonomic nervous system. This suggested that traditional Japanese style bathing might contribute to good health and longevity;however, additional larger-scale studies were needed to confirm or refute this conclusion. 展开更多
关键词 Body Temperature bathing Bath Additive Blood Gas Heart Rate SWEAT
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Hemodynamic Response during Japanese-Style Bathing in Elderly Disabled Subjects
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作者 Naomi Iwane Takuzo Hano +1 位作者 Yumi Koike Kanami Nishihara 《Health》 2014年第21期2999-3004,共6页
Aims: Bathing in deep, Japanese-style bathtubs is associated with high rates of sudden death in the elderly in Japan. The predominant causes of death in such cases are cardiovascular events and drowning. Blood pressur... Aims: Bathing in deep, Japanese-style bathtubs is associated with high rates of sudden death in the elderly in Japan. The predominant causes of death in such cases are cardiovascular events and drowning. Blood pressure changes induced by water pressure and high temperature during bathing may be an important cause of these accidents. Therefore, we investigated the changes in blood pressure, heart rate, and oxygen saturation (SpO2) before and after bathing in elderly Japanese individuals. Methods: Forty-eight elderly (average age, 86.4 ± 7.5 years) persons were enrolled in this study. Results: Changes in systolic blood pressure after bathing correlated negatively with baseline blood pressure before bathing, and participants with baseline systolic blood pressures of <125 mmHg experienced a greater elevation in blood pressure while bathing. Pulse rate was significantly increased after bathing, and the change in pulse rate correlated negatively with the baseline values. SpO2 did not differ significantly during bathing, but changes in SpO2 correlated negatively with baseline values. Lean participants showed a more marked elevation of SpO2, and those with hypertension showed reduced SpO2. Conclusion: These data suggest that the disabled elderly with low blood pressure experience trends in cardiovascular response during bathing which differ from those of young persons. 展开更多
关键词 ELDERLY Blood Pressure Heart Rate SpO2 bathing Japanese-Style BATHTUB
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Examination of the Appropriateness of Teaching Materials for Preventing Dangers during Ablution and Bathing of Infants by Mothers and Family Members
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作者 Sachi Chikazawa Ayako Sasaki 《Health》 CAS 2023年第2期186-214,共29页
Purpose: This study aimed to develop teaching materials to prevent the dangers of ablution and bathing infants, based on the dangerous experiences of mothers and family members, and examine their appropriateness. Meth... Purpose: This study aimed to develop teaching materials to prevent the dangers of ablution and bathing infants, based on the dangerous experiences of mothers and family members, and examine their appropriateness. Methods: A total of 20 midwives and public health nurses were selected as participants. Teaching materials and anonymous self-administered questionnaires were distributed, and the participants were asked to view the teaching materials and fill in the questionnaires. Retrieval was done by mail. The teaching materials included digital content, such as videos, sounds, and characters, which incorporated dangerous situations, preventions, and innovations in ablution and bathing procedures. The analysis was conducted by simple tabulation for each survey item. The free description was coded to preserve anonymity. This study was conducted with the approval of the Research Ethics Review Board of the authors’ affiliated university. Results: The teaching materials were found to be appropriate in terms of suitability to purpose, degree of difficulty of content, ease of viewing the videos, validity of time, appropriateness of expression, and usability. Conclusions: Ablution teaching materials that are used at the present time do not focus on dangers, and to date, no resources on bathing have been used as teaching materials. The created teaching materials in this study can be viewed multiple times, and mothers and family members who are unfamiliar with ablution and bathing can acquire knowledge regarding dangers and danger prevention. The addition of specific preventive measures and countermeasures for the occurrence of danger, along with practice, would result in the development of further appropriate teaching materials to reduce danger and alleviate anxiety. 展开更多
关键词 Ablution bathing DANGER Teaching Material APPROPRIATENESS
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A Survey of Dangers Experienced by Mothers and Families of Infants Aged 3 - 4 Months during Ablution and Bathing
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作者 Sachi Chikazawa Ayako Sasaki 《Health》 2021年第11期1242-1269,共28页
Purpose: The purpose of this study is to explore the dangers experienced by mothers and families of infants aged 3 - 4 months in Japan during ablution and bathing. Method: We distributed an anonymous, self-reported qu... Purpose: The purpose of this study is to explore the dangers experienced by mothers and families of infants aged 3 - 4 months in Japan during ablution and bathing. Method: We distributed an anonymous, self-reported questionnaire at infants’ 3 - 4-month health checkup, which was collected via postal service. 170 valid responses were received and formed our sample data. Descriptive statistical analysis was performed for each category surveyed. Inferential statistics were used to compare the dangerous incidents experienced with regard to differences between primi/multipara and the presence/absence of guidance concerning such incidents. This study was approved by the research ethics committees of the affiliated university. Results: 60.0% of mothers and families experienced dangers while washing their infant in a baby tub or similar apparatus (ablution), and 64.9% did while bathing their infant in the normal bath. For ablution, the most common dangers were, in order, nearly dropping the infant in the water and nearly getting soap suds in the mouth. For bathing, these were nearly getting soap suds in the mouth, near submersion of the face, and nearly dropping the infant in the water. The percentage of mothers and families who did not receive instruction regarding potential dangers and their prevention was 55.9% for ablution and 81.8% for bathing. Conclusion: This study revealed the dangers experienced by mothers and families of infants aged 3 - 4 months in Japan during ablution and bathing. Further consideration into the prevention of these dangers is necessary. 展开更多
关键词 Ablution bathing Incidents EXPERIENCE INFANTS
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Study on sea water pollution mechanism of Xiuying Bathing Beach in Haikou
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作者 Chen Chunhua Wang Lu and Wang Daoru(Ocean Exploitation Planning and Design Research Instituteof Hainan, Haikou 570203, China) 《Acta Oceanologica Sinica》 SCIE CAS CSCD 1996年第3期397-408,共12页
关键词 Study on sea water pollution mechanism of Xiuying bathing Beach in Haikou
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A Comparative Study on the Bathing Cultures and the Spread of Plague Between China and the West-Taking the Spread of the Black Death in China and Europe in the 14th Century as an Example
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作者 YU Meng-qing 《Journal of Literature and Art Studies》 2023年第5期377-382,共6页
An unprecedented catastrophe shrouded over the Chinese Empire ruled by the Yuan Dynasty and Medieval Europe-the Black Death during the 14th century with rapid spread,widespread impact,serious damage to property,and su... An unprecedented catastrophe shrouded over the Chinese Empire ruled by the Yuan Dynasty and Medieval Europe-the Black Death during the 14th century with rapid spread,widespread impact,serious damage to property,and substantial deaths and injuries.In the aftermath of the Black Death,lifestyle changes were made and more sensible bathing habits evolved.In feudal China,Bathing Culture had variously adapted to each dynasty;while its existence in the West was heavily influenced by religion and other factors.In the post-pandemic era,this paper is dedicated to exploring the possible relevance of Bathing Cultures to the Black Death,and to conducting a comparative study of the plague spread in Yuan and Europe and its impact on ethnic Bathing Cultures,reckoning to present informative information to regular prevention and control of the following pandemics. 展开更多
关键词 bathing culture the Black Death pandemic transmission prevention control
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Lhasa Bathing Festival: Night Activities
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《China's Tibet》 2001年第6期40-40,共1页
关键词 Lhasa bathing Festival Night Activities
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BATHING IN MANGPU HOT SPRING IN LHATSE
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《China's Tibet》 2007年第1期40-41,共2页
Lhastse County in Shigatse Prefecture is well-known by multiple names such as the "North Entrance of theQ omolangma,""Food Grains Storage,""Hometown of Tibetan Knives,""Hometown of D... Lhastse County in Shigatse Prefecture is well-known by multiple names such as the "North Entrance of theQ omolangma,""Food Grains Storage,""Hometown of Tibetan Knives,""Hometown of Dorxic (a kind of Tibetan music)" and also "the Way to Pilgrim". "Lhastse", in Tibetan, refers to the "Summit of Manitou". Int he secular world, it is called "Laxog" meaning "the holy place where the sunlight first touches" Naturally, some scholars prefer to dub "Lhastse" as"a place suffering from drought". 展开更多
关键词 bathing IN MANGPU HOT SPRING IN LHATSE
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Preliminary Study on the Effectiveness of Different Durations of Hot Towel Application to the Back during Bed Bathing
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作者 Inaho Shishido Yuka Yamaguchi +2 位作者 Rie Miyata Sakiko Kutomi Rika Yano 《Open Journal of Nursing》 2017年第12期1375-1386,共12页
The purpose of this study was to determine the most effective duration of hot towel application during bed bathing, based on temporal changes in skin surface temperature, towel temperature, and subjective comfort. As ... The purpose of this study was to determine the most effective duration of hot towel application during bed bathing, based on temporal changes in skin surface temperature, towel temperature, and subjective comfort. As a secondary objective, differences in skin surface temperature and subjective comfort for hot towel application on the back and dry towel wiping alone were evaluated. For the first objective, hot towels were applied on the lower back of 20 healthy adults, for different duration (10, 15, and 20 s), with a 10-s duration found to be the most effective. For the second objective, we compared bed bathing with hot towel application to dry wiping alone, n 21 healthy adult participants. A 10-s hot towel application increased the surface temperature of the skin (+0.5℃) and provided a perceived sensation of warmth and comfort. In contrast, dry wiping significantly decreased the surface skin temperature (-0.8℃). In conclusion, hot towel application increased skin surface temperature and improved subjective warmth and comfort during bed bathing. 展开更多
关键词 BED BATH HOT TOWEL APPLICATION Skin Surface Temperature
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Bathing assistive devices and robots for the elderly
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作者 Jian Li Yadong Mo +3 位作者 Shijie Jiang Lifang Ma Ying Zhang Shimin Wei 《Biomimetic Intelligence & Robotics》 2025年第2期36-48,共13页
The issue of aging population has become a severe problem that restricts global development.Thus,the development of bathing robots for the elderly is of great significance for the national strategy of actively address... The issue of aging population has become a severe problem that restricts global development.Thus,the development of bathing robots for the elderly is of great significance for the national strategy of actively addressing population aging.However,there is a lack of systematic review and analysis for the elderly bathing aids and robots,and the trend of the future development is also unclear.Therefore,by reviewing the relevant literature,this paper systematically analyzes the technical characteristics and usage scenarios of the lying,sitting and auxiliary posture,based on the bathing methods,bathing modes,and post bath care,which can clarify the current research status of bathing aids and robots for the elderly.Meanwhile,from the perspectives of the structural design,motion control and information intelligence,the key technologies and existing problems of bathing aids and robots are elaborated,and the relevant technical system is sorted out.Finally,based on the future of technological elderly care and the elderly bathing needs,the development trend of elderly bathing aids and robots is prospected,and the reference and suggestions for its research and development is provided,which has positive research significance. 展开更多
关键词 Elderly people Assistant bathing aids bathing robot Disabled elderly Semi-disabled elderly
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Experience on Improving Blood Gas Index and Complications of Hypothermia Neonates by Bird's Nest-Kangaroo-Bathing-Transport Nursing
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作者 XIALi 《外文科技期刊数据库(文摘版)医药卫生》 2022年第7期133-136,共4页
Objective: to study the effect of birds nest kangaroo bath transport combined nursing on blood gas index and complications of hypothermia neonates. Methods: 58 cases of hypothermia newborns delivered in our hospital f... Objective: to study the effect of birds nest kangaroo bath transport combined nursing on blood gas index and complications of hypothermia neonates. Methods: 58 cases of hypothermia newborns delivered in our hospital from June 2019 to March 2022 were included. They were randomly divided into two groups. The reference group (n 29) carried out routine nursing and the test group (n 29) carried out birds nest kangaroo type bathing transport combined nursing. After nursing, the blood gas index, body temperature improvement, complications and family care satisfaction of the two groups were compared. Results: after nursing, the blood oxygen saturation (SpO2) and arterial blood oxygen partial pressure (PaO2) in the test group were significantly higher than those in the reference group P 0.05 (t 2.806, t 2.853);The body temperature of the experimental group on the 1st, 7th, 14th and 24th day of birth was significantly higher than that of the reference group (P 0.05) (t 9.157, t 15.211, t 6.608, t 4.981);The incidence of complications in the test group was also significantly lower than that in the reference group (P 0.05)( χ24.061);Compared with the reference group, the nursing satisfaction of family members of newborns in the test group was significantly higher (P 0.05)( χ 24.061). Conclusion: the combined application of birds nest kangaroo bath transport nursing care for hypothermia newborns can effectively reduce their oxygen consumption, improve blood gas indicators, promote the recovery of childrens body temperature, reduce complications, and improve the satisfaction of family members with nursing care, which is worthy of promotion. 展开更多
关键词 HYPOTHERMIA NEWBORN bird nest style kangaroo style bath transport care blood gas indices
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强直性脊柱炎患者使用生物制剂治疗后疾病活动度影响因素研究
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作者 王赛赛 祁金文 +3 位作者 王天乐 邹玉琼 胡林均 程迪 《浙江医学》 2025年第5期501-505,共5页
目的探讨强直性脊柱炎(AS)患者使用生物制剂治疗后疾病活动度的影响因素。方法回顾性选取2023年1至7月浙江省人民医院收治的109例AS患者为研究对象,均接受规律的生物制剂治疗>6个月且达到稳定期,无新发关节外表现或症状恶化。根据治... 目的探讨强直性脊柱炎(AS)患者使用生物制剂治疗后疾病活动度的影响因素。方法回顾性选取2023年1至7月浙江省人民医院收治的109例AS患者为研究对象,均接受规律的生物制剂治疗>6个月且达到稳定期,无新发关节外表现或症状恶化。根据治疗后Bath AS疾病活动度指数(BASDAI)分为<4分88例(低活动组)和≥4分21例(高活动组)。采用线上和线下相结合形式进行问卷调查,收集一般人口学资料、生活习惯、心理状况等数据,比较低活动组与高活动组AS患者调查内容。采用多因素logistic回归分析AS患者使用生物制剂治疗后疾病活动度的影响因素。结果与高活动组比较,低活动组女性、吸烟比例均较低,运动频率<3次/周以及偶尔感到紧张或痛苦、对以往感兴趣的事情一直感兴趣、一直或经常能看到事物好的一面并因此开怀、一直或经常感到愉快的比例均较高,生物制剂使用时间较长,差异均有统计学意义(均P<0.05)。控制年龄、体质指数、病程、合并使用其他药物、生物制剂种类、入睡时间、运动频率、血压等混杂因素后,发现女性(OR=9.782)、生物制剂使用时间(OR=0.899)、吸烟(OR=5.273)以及对以往感兴趣的事情现在只有一点兴趣(OR=21.461)均是AS患者使用生物制剂治疗后疾病活动度的独立影响因素(均P<0.05)。结论性别、生物制剂使用时间、吸烟、心理状况对AS患者使用生物制剂治疗后疾病活动度均有影响。 展开更多
关键词 强直性脊柱炎 生物制剂 Bath强直性脊柱炎疾病活动度指数 心理状况
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Clinical Efficacy and Safety of Bathing with Chinese Medicine Taohong Siwu Decoction(桃红四物汤) for Treatment of Diffuse Cutaneous Systemic Sclerosis:A Randomized Placebo-Controlled Trial 被引量:6
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作者 ZHOU Jing YANG Dong +3 位作者 ZHOU Shu-hong WANG Jin-ping LIU Yue-shu WANG Shu-lan 《Chinese Journal of Integrative Medicine》 SCIE CAS CSCD 2018年第3期185-192,共8页
Objective:To examine the efficacy and safety of bathing therapy with Taohong Siwu Decoction(桃红四物汤,TSD) in the treatment of early-stage,mild-moderate diffuse cutaneous systemic sclerosis(dc SSc).Methods:This... Objective:To examine the efficacy and safety of bathing therapy with Taohong Siwu Decoction(桃红四物汤,TSD) in the treatment of early-stage,mild-moderate diffuse cutaneous systemic sclerosis(dc SSc).Methods:This randomized,placebo-controlled trial enrolled 148 men and women(18–60 years) with dc SSc(disease duration 12 months) and baseline modified Rodnan skin score(MRSS) 10.Patients were randomized into a TSD group(71 cases bathing with TSD plus oral prednisone) or control group(71 cases bathing with placebo plus oral prednisone).Bathing(40 ℃,30 min) of the upper and lower limbs was carried out once daily for 12 consecutive weeks.The primary outcome measure was MRSS;secondary outcomes were Raynaud's phenomenon(RP) score,quality of life(QOL),physician visual analogue scale(VAS),patient VAS,percent predicted diffusing capacity for carbon monoxide(DLCO),percent predicted forced vital capacity(FVC),erythrocyte sedimentation rate(ESR),C-reactive protein(CRP) level and overall treatment effect.Results:The final analysis included 135 patients(control group,68 cases;TSD group,67 cases).Primary and secondary outcome measures after 2 weeks of treatment showed no improvement(versus baseline) in both groups,with no differences between groups.At 12 weeks,QOL,physician VAS,patient VAS,ESR and CRP were improved in both groups,but MRSS and RP score were improved only in the TSD group(all P〈0.05).MRSS,RP score,QOL,physician VAS,patient VAS,ESR and CRP differed significantly between groups(all P〈0.05).Meanwhile,the overall treatment effect was significantly higher in the TSD group than in the control group(P〈0.05).Adverse events in the two groups were similar(P〉0.05).Conclusions:Bathing with TSD plus oral prednisone achieves better outcomes than oral prednisone alone in patients with dcS Sc and is not associated with serious adverse events. 展开更多
关键词 Chinese medicine bathing therapy systemic sclerosis treatment efficacy adverse effects
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注射用重组人Ⅱ型肿瘤坏死因子受体-抗体融合蛋白穴位注射联合骨痛灵酊外敷在强直性脊柱炎患者中的应用效果
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作者 洪仪慧 黄萍 刘圣徽 《中国当代医药》 2025年第10期105-109,共5页
目的探讨注射用重组人Ⅱ型肿瘤坏死因子受体-抗体融合蛋白穴位注射联合骨痛灵酊外敷在强直性脊柱炎患者中的应用效果。方法选取2021年4月至2024年4月九江市第一人民医院风湿免疫科收治的212例强直性脊柱炎患者作为研究对象,按照不同治... 目的探讨注射用重组人Ⅱ型肿瘤坏死因子受体-抗体融合蛋白穴位注射联合骨痛灵酊外敷在强直性脊柱炎患者中的应用效果。方法选取2021年4月至2024年4月九江市第一人民医院风湿免疫科收治的212例强直性脊柱炎患者作为研究对象,按照不同治疗方式分为联合组(108例)与对照组(104例)。联合组采用注射用重组人Ⅱ型肿瘤坏死因子受体-抗体融合蛋白穴位注射联合骨痛灵酊外敷方法,对照组采用骨痛灵酊外敷方法。比较两组患者的治疗效果、疼痛程度、Bath强直性脊柱炎功能指数(BASFI)、Bath强直性脊柱炎病情活动性指数(BASDAI)、炎症指标[基质金属蛋白酶-3(MMP-3)、骨形态发生蛋白-2(BMP-2)、肿瘤坏死因子-α(TNF-α)、C反应蛋白(CRP)]、不良反应情况。结果联合组治疗2、6、12周后视觉模拟评分法(VAS)评分低于对照组,差异有统计学意义(P<0.05)。联合组治疗后总有效率高于对照组,BASFI、BASDAI评分及BMP-2、MMP-3、CRP和TNF-α水平低于对照组,差异有统计学意义(P<0.05)。两组患者不良反应总发生率比较,差异无统计学意义(P>0.05)。结论强直性脊柱炎患者采用注射用重组人Ⅱ型肿瘤坏死因子受体-抗体融合蛋白穴位注射与骨痛灵酊外敷联合治疗,可提高治疗效果,缓解疼痛,改善BASDAI评分,降低炎症因子水平,提升脊柱功能,安全性良好。 展开更多
关键词 注射用重组人Ⅱ型肿瘤坏死因子受体-抗体融合蛋白 穴位注射 骨痛灵酊 强直性脊柱炎 血清炎症因子 Bath强直性脊柱炎病情活动性指数
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Clinical Efficacy and Medication Patterns of Chinese Herbal Bath Combined with Head Massage in Treating Insomnia
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作者 Chao ZUO Haiju LI +1 位作者 Can ZHANG Xueping ZHANG 《Medicinal Plant》 2025年第3期59-61,共3页
[Objectives]To systematically evaluate the clinical efficacy of head massage combined with Chinese herbal bath in treating insomnia and analyze its herbal medication patterns.[Methods]Clinical data of 200 chronic inso... [Objectives]To systematically evaluate the clinical efficacy of head massage combined with Chinese herbal bath in treating insomnia and analyze its herbal medication patterns.[Methods]Clinical data of 200 chronic insomnia patients treated at the Sleep Disorder Center of Taihe Hospital from January 2020 to December 2024 were retrospectively analyzed.Patients were randomly divided into observation group and control group(n=100 each).The observation group received head massage combined with Chinese herbal bath therapy,while the control group received Chinese herbal bath alone.The Pittsburgh Sleep Quality Index(PSQI)was used for efficacy evaluation,and statistical analysis was performed on the frequency of herbal medications in herbal herbal bath formulas.[Results]The PSQI score improvement in the observation group(8.44±1.87)was significantly better than that in the control group(5.74±1.93)(P<0.01).Herbal formulas for external bath primarily contained mind-calming and heart-nourishing herbs(fried Ziziphi Spinosae Semen,Concha Margaritifera)and heat-clearing herbs(Rhizoma Coptidis,Radix Scutellariae).[Conclusions]The combination of head massage and Chinese herbal bath can significantly improve sleep quality in insomnia patients,demonstrating superior clinical efficacy compared with Chinese herbal bath alone.This combined therapy shows good safety and operability,warranting promotion in primary and specialized medical institutions. 展开更多
关键词 HEAD MASSAGE CHINESE HERBAL bath INSOMNIA TCM treatment Clinical efficacy PSQI score
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