A gold nanohole/disk array-based plasmonic fiber end-facet sensing probe is proposed and demonstrated experimentally,where the hybrid plasmon mode on the top surface used for sensing is excited by the cooperative effe...A gold nanohole/disk array-based plasmonic fiber end-facet sensing probe is proposed and demonstrated experimentally,where the hybrid plasmon mode on the top surface used for sensing is excited by the cooperative effect of the near-field coupling between the nanohole and the nanodisk,as well as the localized surface plasmon of the nanodisk.The high-quality integration of the nanohole/disk array on the fiber end facet is achieved by combining nanoimprint lithography on a planar substrate with fiber ultraviolet(UV)-curable adhesive transfer techniques.As a result,the fabricated fiber probe experimentally exhibits a moderately high bulk refractive index sensitivity of~196.91 nm/RIU and excellent surface sensitivity.Furthermore,the specific identification and determination of protein molecules verify their sensitivity analysis capabilities for future bioassays.This work provides a feasible plasmonic excitation strategy and enables batch-manufactured technology for nanostructure-based fiber probes to break through the current bottlenecks in biosensing applications.展开更多
A good wound dressing needs to promote wound healing and tissue repair when the skin is injured.In this study,a self-made spherical section free surface electrospinning device was used to produce large quantities of e...A good wound dressing needs to promote wound healing and tissue repair when the skin is injured.In this study,a self-made spherical section free surface electrospinning device was used to produce large quantities of electrospun porous polylactic acid(PLA)/chitosan(CS)/aloin nanofiber membranes(NFMs)for antibacterial wound dressing.The porous structures of PLAbased nanofibers were controlled by adjusting the weight ratios of mixed solvent and solute.The results showed that highquality porous PLA/CS/aloin(PCA)NFMs were obtained when the weight ratios of chloroform/N,N-dimethylformamide and PLA:CS were 90/10 and 7:1,respectively.The porous PCA NFMs exhibited high porosity,acceptable mechanical properties,moderate hydrophobicity,good swelling property,and high water vapor transmission rate.Moreover,they also showed excellent blood coagulative,antibacterial,biocompatible properties,which had the potential to be used in the application of antibacterial wound dressings.展开更多
基金supported by the National Natural Science Foundation of China(Nos.12274052 and 62171076)the Natural Science Foundation of Liaoning Province(No.2022MS-134)the Fundamental Research Funds for the Central Universities(Nos.DUT24ZD203 and DUT23BK063)。
文摘A gold nanohole/disk array-based plasmonic fiber end-facet sensing probe is proposed and demonstrated experimentally,where the hybrid plasmon mode on the top surface used for sensing is excited by the cooperative effect of the near-field coupling between the nanohole and the nanodisk,as well as the localized surface plasmon of the nanodisk.The high-quality integration of the nanohole/disk array on the fiber end facet is achieved by combining nanoimprint lithography on a planar substrate with fiber ultraviolet(UV)-curable adhesive transfer techniques.As a result,the fabricated fiber probe experimentally exhibits a moderately high bulk refractive index sensitivity of~196.91 nm/RIU and excellent surface sensitivity.Furthermore,the specific identification and determination of protein molecules verify their sensitivity analysis capabilities for future bioassays.This work provides a feasible plasmonic excitation strategy and enables batch-manufactured technology for nanostructure-based fiber probes to break through the current bottlenecks in biosensing applications.
基金The work is supported financially by National Natural Science Foundation of China(Grant no.11672198)Jiangsu Higher Education Institutions of China(Grant no.20KJA130001)+1 种基金Six Talent Peaks Project of Jiangsu Province(Grant no.GDZB-050)PAPD(A Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions).
文摘A good wound dressing needs to promote wound healing and tissue repair when the skin is injured.In this study,a self-made spherical section free surface electrospinning device was used to produce large quantities of electrospun porous polylactic acid(PLA)/chitosan(CS)/aloin nanofiber membranes(NFMs)for antibacterial wound dressing.The porous structures of PLAbased nanofibers were controlled by adjusting the weight ratios of mixed solvent and solute.The results showed that highquality porous PLA/CS/aloin(PCA)NFMs were obtained when the weight ratios of chloroform/N,N-dimethylformamide and PLA:CS were 90/10 and 7:1,respectively.The porous PCA NFMs exhibited high porosity,acceptable mechanical properties,moderate hydrophobicity,good swelling property,and high water vapor transmission rate.Moreover,they also showed excellent blood coagulative,antibacterial,biocompatible properties,which had the potential to be used in the application of antibacterial wound dressings.
