The clinical application and basic research of Draba nemerosa Hebecarpa jujube diarrhoea lung soup focus on respiratory diseases and circulatory diseases, and its clinical application is more compared with the basic r...The clinical application and basic research of Draba nemerosa Hebecarpa jujube diarrhoea lung soup focus on respiratory diseases and circulatory diseases, and its clinical application is more compared with the basic research, and Draba nemerosa Hebecarpa jujube diarrhoea lung soup is mostly used in the form of “Draba nemerosa Hebecarpa Hebecarpa jujube diarrhoea lung soup with additional subtractions or other formulas combining Draba nemerosa Hebecarpa Hebecarpa Hebecarpa jujube diarrhoea lung soup” in the clinical application. This article will focus on the main mechanisms of Draba nemerosa Hebecarpa jujube diarrhoea lung soup and its main components in the treatment of respiratory and circulatory diseases, and will give a review of the basic research on Draba nemerosa Hebecarpa Hebecarpa jujube diarrhoea lung soup as follows.展开更多
This paper deals with all aspects of liver alveolar echinococcosis (AE) including epidemiology, pathology, clinical manifestations, imaging examinations, diagnosis and differential diagnosis, surgical treatment and ch...This paper deals with all aspects of liver alveolar echinococcosis (AE) including epidemiology, pathology, clinical manifestations, imaging examinations, diagnosis and differential diagnosis, surgical treatment and chemotherapy.The review is not only based on personal clinical experiences but also in combination with relative basic research such as proliferation and growth of alveococcus, preclinical studies of a novel compound extracted from TCM for treatment of liver AE, and molecular immunology used for specific AE diagnosis, etc.展开更多
In order to understand the fundamental questions of the biology of life and to duplicate the pathogenesis of human diseases, animal models using different experimental animals, such as rodents, Drosophila, Caenorhabdi...In order to understand the fundamental questions of the biology of life and to duplicate the pathogenesis of human diseases, animal models using different experimental animals, such as rodents, Drosophila, Caenorhabditis elegans, and zebrafish, have been established and used widely for many decades. The controllability of environmental conditions, the high reproducibility, the ease of scale and the comparability of results, as well as the ability to use different standards for ethical protocols, all make an animal model the ideal tool for carrying out studies on human diseases and the development of novel pharmaceuticals and new therapies （Xue et al., 2014）. An ideal animal model should reflect the complete spectra of a specific human disease, with similar features on the following key issues： （1） genetic basis; （2） anatomy and physiology; （3） pathological response（s） and underlying mechanism（s）; （4） phenotypic endpoints as clinical studies; （5） responsiveness to known drugs with clinical efficacy; and （6） prediction of clinical efficacy （McGonigle and Ruggeri, 2014）.展开更多
1 INTRODUCTION The tropical Indo-Pacific Oceans span over twothirds of the global tropical oceans.A major warm pool with the highest large-scale sea surface temperature of the global oceans is located in the western P...1 INTRODUCTION The tropical Indo-Pacific Oceans span over twothirds of the global tropical oceans.A major warm pool with the highest large-scale sea surface temperature of the global oceans is located in the western Pacific and eastern Indian Oceans.The climate systems over the tropical Pacific and Indian Oceans are subject to strong ocean-atmosphere coupling at multiple scales from intraseasonal to interannual,and to centennial.The展开更多
The liver is a multifaceted organ that is responsible for many critical functions encompassing amino acid,carbohydrate,and lipid metabolism,all of which make a healthy liver essential for the human body.Contemporary i...The liver is a multifaceted organ that is responsible for many critical functions encompassing amino acid,carbohydrate,and lipid metabolism,all of which make a healthy liver essential for the human body.Contemporary imaging methodologies have remarkable diagnostic accuracy in discerning focal liver lesions;however,a comprehensive understanding of diffuse liver diseases is a requisite for radiologists to accurately diagnose or predict the progression of such lesions within clinical contexts.Nonetheless,the conventional attributes of radiological features,including morphology,size,margin,density,signal intensity,and echoes,limit their clinical utility.Radiomics is a widely used approach that is characterized by the extraction of copious image features from radiographic depictions,which gives it considerable potential in addressing this limitation.It is worth noting that functional or molecular alterations occur significantly prior to the morphological shifts discernible by imaging modalities.Consequently,the explication of potential mechanisms by multiomics analyses(encompassing genomics,epigenomics,transcriptomics,proteomics,and metabolomics)is essential for investigating putative signal pathway regulations from a radiological viewpoint.In this review,we elaborate on the principal pathological categorizations of diffuse liver diseases,the evaluation of multiomics approaches pertaining to diffuse liver diseases,and the prospective value of predictive models.Accordingly,the overarching objective of this review is to scrutinize the interrelations between radiological features and bioinformatics as well as to consider the development of prediction models predicated on radiobioinformatics as integral components of clinical decision support systems for diffuse liver diseases.展开更多
Comparing conventional practice and experience of some foreign countries financing their basic research programs, this article analyzes and explores the scope, funding principles, channels and forms of China’s basic ...Comparing conventional practice and experience of some foreign countries financing their basic research programs, this article analyzes and explores the scope, funding principles, channels and forms of China’s basic research input.展开更多
Under the joint sponsorship ofthe Ministry of Science and Tech-nology, Ministry of Education, theChinese Academy of Science(CAS), the Chinese Academy ofEngineering (CAE) and the Na-tional Natural Science Foundationof ...Under the joint sponsorship ofthe Ministry of Science and Tech-nology, Ministry of Education, theChinese Academy of Science(CAS), the Chinese Academy ofEngineering (CAE) and the Na-tional Natural Science Foundationof China (NSFC), a national con-ference on basic research was heldfron March 27-29 in Beijing.展开更多
The main body of basic research in contemporary science has been evolved from mental adventures motivated by an individual’ s curiosity in Newtonian times into large-scale and normally wellorganized social behaviors ...The main body of basic research in contemporary science has been evolved from mental adventures motivated by an individual’ s curiosity in Newtonian times into large-scale and normally wellorganized social behaviors driven by keen desires and always oriented by primary social demands. By now, very probably there are few people still claiming that basic research is unnecessary in this country. And the problem needing our discussion is how to develop our basic research projects most effectively by using the limited funding resources available. First of all, file current S&T system needs an institutional facelift and the rampant展开更多
Basic research is one of the main tasks constantly undertaken by the CAS.Its evolutionary course, just like the growth itinerary of the whole Academy,began in the 1950s,with a robust development from the late 1950s to...Basic research is one of the main tasks constantly undertaken by the CAS.Its evolutionary course, just like the growth itinerary of the whole Academy,began in the 1950s,with a robust development from the late 1950s to the early 1960s, the ravages during the chaotic decade of the "cultural revolution", the succeeding institutional readjustment and academic revival since the implementation of the on-going reform drive and the "open-door" policy. During the early founding years of the CAS, there were only odds and ends attained from its research work in some disciplines展开更多
China made great strides in thefields of basic research in2000 in terms of projectinitiation, infrastructureimprovement, and the developmentand encouragement of talentedpersonnel. Last year more than five billionyuan ...China made great strides in thefields of basic research in2000 in terms of projectinitiation, infrastructureimprovement, and the developmentand encouragement of talentedpersonnel. Last year more than five billionyuan (US$602 million) was pouredinto basic research projects in China.展开更多
The Ministry of Science and Technology (MOST) re-cently announced China’stop ten news events in ba-sic research in 2000. 1. Research into thenanomaterial scored re-markable
Basic research features its indelible contribution to and energetic promotion of scientific cause and advancing social progress. This article explores its vital position and rewarding role in creating socio-economic b...Basic research features its indelible contribution to and energetic promotion of scientific cause and advancing social progress. This article explores its vital position and rewarding role in creating socio-economic benefits by reviewing the development and marketing success of a new drug, "Di’ aoxinxuekang".展开更多
Mankind is going to stride across the threshold of the new century while world science advances by leaps and bounds. At the same time, China will enter a comparatively well-off state in terms of its economic developme...Mankind is going to stride across the threshold of the new century while world science advances by leaps and bounds. At the same time, China will enter a comparatively well-off state in terms of its economic development and its next step forward is to be a moderately developed country in the international community. At the 15th National Congress展开更多
The implementation of structural readjustment is the strategic consideration to deepening reforms in the Chinese Academy of Sciences (CAS). and the readjustment of basic research is one of its major contents. By analy...The implementation of structural readjustment is the strategic consideration to deepening reforms in the Chinese Academy of Sciences (CAS). and the readjustment of basic research is one of its major contents. By analyzing the historical roles, status quo and existing problems in CAS basic research, this article points out the needs for structural readjustment and puts forward some suggestions on this point in basic research in the context of the possible models of basic structural units for basic research and their ways of combination as well as the implementing procedures of structural readjustment.展开更多
As a national institution for scientific research and a component of the national innovation system, CAS should and must make key contributions to the great national rejuvenation of the country. Keeping this in mind, ...As a national institution for scientific research and a component of the national innovation system, CAS should and must make key contributions to the great national rejuvenation of the country. Keeping this in mind, CAS has developed four developmental targets for its basic research. This was revealed at a CAS conference on basic research held June 11-12 in Beijing.展开更多
In a 1997 directive, Chinese President Jiang Zemin instructed us: Basic research is very important. The advances of modem civilization have proven that every breakthrough in basic research means an uplift in man’s ab...In a 1997 directive, Chinese President Jiang Zemin instructed us: Basic research is very important. The advances of modem civilization have proven that every breakthrough in basic research means an uplift in man’s ability to remould the objective world and gives rise to a tremendous and inestima- ble driving push to S&T innovation, hi-tech industrialization and socio-economic progress. In his keynote report at the CPC’ s 15th National Congress, once again he stressed that "Science and technology are the primary production force and S&T progress is the decisive factor for the economic development." In his report on behalf of the national government at the fifth session of the 8th NPC,展开更多
Objective To explore a new approach for improving therapeutic effects and minimizing complications of ventriculoperitoneal shunt(VPS) . Methods The lengthof and lower edge of the greater omentum were measured and anal...Objective To explore a new approach for improving therapeutic effects and minimizing complications of ventriculoperitoneal shunt(VPS) . Methods The lengthof and lower edge of the greater omentum were measured and analyzed in 28 autopsies (16 adults and 12 children) and laparoscopic surgeries. 95 cases of hydrocephalus treated by MIVPS(minimally invasive ventriculoperitoneal shunt) were retrospectively reviewed. The depth and positions展开更多
Since its founding in 1949,the Chinese Academy of Sciences (CAS) has committed itself to gaining honor for our nation by successfully scaling heights of contemporary science.To this end.Chinese scientists have striven...Since its founding in 1949,the Chinese Academy of Sciences (CAS) has committed itself to gaining honor for our nation by successfully scaling heights of contemporary science.To this end.Chinese scientists have striven to exert themselves from generation to generation in a courageous and unflagging way. During the period of the national Eighth Five-year Plan(1991—1995), the scientists with the CAS went on working at the frontiers of international science.According to statistics,there were 205 key R&D projects展开更多
A major basic research projectin the field of neurosciencewas launched on November26 last year at the Shanghai-basedInstitute of Neuroscience of the Chi-nese Academy of Sciences(CAS).
文摘The clinical application and basic research of Draba nemerosa Hebecarpa jujube diarrhoea lung soup focus on respiratory diseases and circulatory diseases, and its clinical application is more compared with the basic research, and Draba nemerosa Hebecarpa jujube diarrhoea lung soup is mostly used in the form of “Draba nemerosa Hebecarpa Hebecarpa jujube diarrhoea lung soup with additional subtractions or other formulas combining Draba nemerosa Hebecarpa Hebecarpa Hebecarpa jujube diarrhoea lung soup” in the clinical application. This article will focus on the main mechanisms of Draba nemerosa Hebecarpa jujube diarrhoea lung soup and its main components in the treatment of respiratory and circulatory diseases, and will give a review of the basic research on Draba nemerosa Hebecarpa Hebecarpa jujube diarrhoea lung soup as follows.
文摘This paper deals with all aspects of liver alveolar echinococcosis (AE) including epidemiology, pathology, clinical manifestations, imaging examinations, diagnosis and differential diagnosis, surgical treatment and chemotherapy.The review is not only based on personal clinical experiences but also in combination with relative basic research such as proliferation and growth of alveococcus, preclinical studies of a novel compound extracted from TCM for treatment of liver AE, and molecular immunology used for specific AE diagnosis, etc.
文摘In order to understand the fundamental questions of the biology of life and to duplicate the pathogenesis of human diseases, animal models using different experimental animals, such as rodents, Drosophila, Caenorhabditis elegans, and zebrafish, have been established and used widely for many decades. The controllability of environmental conditions, the high reproducibility, the ease of scale and the comparability of results, as well as the ability to use different standards for ethical protocols, all make an animal model the ideal tool for carrying out studies on human diseases and the development of novel pharmaceuticals and new therapies （Xue et al., 2014）. An ideal animal model should reflect the complete spectra of a specific human disease, with similar features on the following key issues： （1） genetic basis; （2） anatomy and physiology; （3） pathological response（s） and underlying mechanism（s）; （4） phenotypic endpoints as clinical studies; （5） responsiveness to known drugs with clinical efficacy; and （6） prediction of clinical efficacy （McGonigle and Ruggeri, 2014）.
文摘1 INTRODUCTION The tropical Indo-Pacific Oceans span over twothirds of the global tropical oceans.A major warm pool with the highest large-scale sea surface temperature of the global oceans is located in the western Pacific and eastern Indian Oceans.The climate systems over the tropical Pacific and Indian Oceans are subject to strong ocean-atmosphere coupling at multiple scales from intraseasonal to interannual,and to centennial.The
基金National Natural Science Foundation of China,Grant/Award Number:81960338Science and Technology Projects of Guizhou Province,Grant/Award Numbers:Qiankehejichu-ZK[2022]422,Qiankehejichu-ZK[2023]353。
文摘The liver is a multifaceted organ that is responsible for many critical functions encompassing amino acid,carbohydrate,and lipid metabolism,all of which make a healthy liver essential for the human body.Contemporary imaging methodologies have remarkable diagnostic accuracy in discerning focal liver lesions;however,a comprehensive understanding of diffuse liver diseases is a requisite for radiologists to accurately diagnose or predict the progression of such lesions within clinical contexts.Nonetheless,the conventional attributes of radiological features,including morphology,size,margin,density,signal intensity,and echoes,limit their clinical utility.Radiomics is a widely used approach that is characterized by the extraction of copious image features from radiographic depictions,which gives it considerable potential in addressing this limitation.It is worth noting that functional or molecular alterations occur significantly prior to the morphological shifts discernible by imaging modalities.Consequently,the explication of potential mechanisms by multiomics analyses(encompassing genomics,epigenomics,transcriptomics,proteomics,and metabolomics)is essential for investigating putative signal pathway regulations from a radiological viewpoint.In this review,we elaborate on the principal pathological categorizations of diffuse liver diseases,the evaluation of multiomics approaches pertaining to diffuse liver diseases,and the prospective value of predictive models.Accordingly,the overarching objective of this review is to scrutinize the interrelations between radiological features and bioinformatics as well as to consider the development of prediction models predicated on radiobioinformatics as integral components of clinical decision support systems for diffuse liver diseases.
文摘Comparing conventional practice and experience of some foreign countries financing their basic research programs, this article analyzes and explores the scope, funding principles, channels and forms of China’s basic research input.
文摘Under the joint sponsorship ofthe Ministry of Science and Tech-nology, Ministry of Education, theChinese Academy of Science(CAS), the Chinese Academy ofEngineering (CAE) and the Na-tional Natural Science Foundationof China (NSFC), a national con-ference on basic research was heldfron March 27-29 in Beijing.
文摘The main body of basic research in contemporary science has been evolved from mental adventures motivated by an individual’ s curiosity in Newtonian times into large-scale and normally wellorganized social behaviors driven by keen desires and always oriented by primary social demands. By now, very probably there are few people still claiming that basic research is unnecessary in this country. And the problem needing our discussion is how to develop our basic research projects most effectively by using the limited funding resources available. First of all, file current S&T system needs an institutional facelift and the rampant
文摘Basic research is one of the main tasks constantly undertaken by the CAS.Its evolutionary course, just like the growth itinerary of the whole Academy,began in the 1950s,with a robust development from the late 1950s to the early 1960s, the ravages during the chaotic decade of the "cultural revolution", the succeeding institutional readjustment and academic revival since the implementation of the on-going reform drive and the "open-door" policy. During the early founding years of the CAS, there were only odds and ends attained from its research work in some disciplines
文摘China made great strides in thefields of basic research in2000 in terms of projectinitiation, infrastructureimprovement, and the developmentand encouragement of talentedpersonnel. Last year more than five billionyuan (US$602 million) was pouredinto basic research projects in China.
文摘The Ministry of Science and Technology (MOST) re-cently announced China’stop ten news events in ba-sic research in 2000. 1. Research into thenanomaterial scored re-markable
文摘Basic research features its indelible contribution to and energetic promotion of scientific cause and advancing social progress. This article explores its vital position and rewarding role in creating socio-economic benefits by reviewing the development and marketing success of a new drug, "Di’ aoxinxuekang".
文摘Mankind is going to stride across the threshold of the new century while world science advances by leaps and bounds. At the same time, China will enter a comparatively well-off state in terms of its economic development and its next step forward is to be a moderately developed country in the international community. At the 15th National Congress
文摘The implementation of structural readjustment is the strategic consideration to deepening reforms in the Chinese Academy of Sciences (CAS). and the readjustment of basic research is one of its major contents. By analyzing the historical roles, status quo and existing problems in CAS basic research, this article points out the needs for structural readjustment and puts forward some suggestions on this point in basic research in the context of the possible models of basic structural units for basic research and their ways of combination as well as the implementing procedures of structural readjustment.
文摘As a national institution for scientific research and a component of the national innovation system, CAS should and must make key contributions to the great national rejuvenation of the country. Keeping this in mind, CAS has developed four developmental targets for its basic research. This was revealed at a CAS conference on basic research held June 11-12 in Beijing.
文摘In a 1997 directive, Chinese President Jiang Zemin instructed us: Basic research is very important. The advances of modem civilization have proven that every breakthrough in basic research means an uplift in man’s ability to remould the objective world and gives rise to a tremendous and inestima- ble driving push to S&T innovation, hi-tech industrialization and socio-economic progress. In his keynote report at the CPC’ s 15th National Congress, once again he stressed that "Science and technology are the primary production force and S&T progress is the decisive factor for the economic development." In his report on behalf of the national government at the fifth session of the 8th NPC,
文摘Objective To explore a new approach for improving therapeutic effects and minimizing complications of ventriculoperitoneal shunt(VPS) . Methods The lengthof and lower edge of the greater omentum were measured and analyzed in 28 autopsies (16 adults and 12 children) and laparoscopic surgeries. 95 cases of hydrocephalus treated by MIVPS(minimally invasive ventriculoperitoneal shunt) were retrospectively reviewed. The depth and positions
文摘Since its founding in 1949,the Chinese Academy of Sciences (CAS) has committed itself to gaining honor for our nation by successfully scaling heights of contemporary science.To this end.Chinese scientists have striven to exert themselves from generation to generation in a courageous and unflagging way. During the period of the national Eighth Five-year Plan(1991—1995), the scientists with the CAS went on working at the frontiers of international science.According to statistics,there were 205 key R&D projects
文摘A major basic research projectin the field of neurosciencewas launched on November26 last year at the Shanghai-basedInstitute of Neuroscience of the Chi-nese Academy of Sciences(CAS).
