I. INTRODUCTIONAlthough the PCR (polymerase chain reaction )combined with ASO (allele-specific oligonucleotide) probe hybridization has greatly facilitated the gene diagnosis and the prenatal diagnosis of beta-thalass...I. INTRODUCTIONAlthough the PCR (polymerase chain reaction )combined with ASO (allele-specific oligonucleotide) probe hybridization has greatly facilitated the gene diagnosis and the prenatal diagnosis of beta-thalassemia, the methodology requires the use of radioactive probes, and it is rather time-consuming and still technically complex. To simplify展开更多
基金Project supported by the National 863 Research Grant.
文摘I. INTRODUCTIONAlthough the PCR (polymerase chain reaction )combined with ASO (allele-specific oligonucleotide) probe hybridization has greatly facilitated the gene diagnosis and the prenatal diagnosis of beta-thalassemia, the methodology requires the use of radioactive probes, and it is rather time-consuming and still technically complex. To simplify
