Objective To explore the expression of CK19, CK20 and bFGF in transitional cell carcinoma of the bladder (TCC) and their biological implication.Methods Samples from 54 patients with TCC were examined for expression of...Objective To explore the expression of CK19, CK20 and bFGF in transitional cell carcinoma of the bladder (TCC) and their biological implication.Methods Samples from 54 patients with TCC were examined for expression of CK19, CK20 and bFGF.Results There was a significant difference in CK19 expression between relapse and non-relapse groups ( P < 0.01) ; no significant difference was found among groups with different pathological grades and clinical stages ( P > 0.05). There were significant differences in CK20 expression among groups with different pathological grades ( P < 0.05) and clinical stages ( P < 0.01) and between the relapse and non-relapse groups( P < 0.000 1) . The expression of bFGF was significantly different among groups with different pathological grades and clinical stages and between the relapse and non-relapse groups ( P < 0.05) .Conclusion The expression of CK19, CK20 and bFGF is closely associated with their biological behavior and among them bFGF is primarily secreted by TCC tumor tissues.展开更多
文摘Objective To explore the expression of CK19, CK20 and bFGF in transitional cell carcinoma of the bladder (TCC) and their biological implication.Methods Samples from 54 patients with TCC were examined for expression of CK19, CK20 and bFGF.Results There was a significant difference in CK19 expression between relapse and non-relapse groups ( P < 0.01) ; no significant difference was found among groups with different pathological grades and clinical stages ( P > 0.05). There were significant differences in CK20 expression among groups with different pathological grades ( P < 0.05) and clinical stages ( P < 0.01) and between the relapse and non-relapse groups( P < 0.000 1) . The expression of bFGF was significantly different among groups with different pathological grades and clinical stages and between the relapse and non-relapse groups ( P < 0.05) .Conclusion The expression of CK19, CK20 and bFGF is closely associated with their biological behavior and among them bFGF is primarily secreted by TCC tumor tissues.
