The inclusion complex of lappaconitine (Lap) with b-cyclodextrin (b-CD) has been studied by the differential scanning calorimetry (DSC) and 1H-NMR, 2D-NMR spectroscopy. The structure of the complex has been deduced.
Using two b-cyclodextrin derivatives (CDs) with long chain of acyl groups as chiral stationary phases (CSPs) of capillary gas chromatography (CGC), the enantiomers of racemic allethrone and propargyllone were well res...Using two b-cyclodextrin derivatives (CDs) with long chain of acyl groups as chiral stationary phases (CSPs) of capillary gas chromatography (CGC), the enantiomers of racemic allethrone and propargyllone were well resolved after derived with acetyl chloride. The enantiomer excess values (e.e.%) of 1S-allethrone and 1S-propargyllone were also determined successfully using these CDs.展开更多
A highly sensitive and selective electrochemical chiral sensor was developed based on the competitive supramolecular interaction of carbon nanofibers(CNFs)embedded sulfobutyl ether-b-cyclodextrin(SBEb-CD)with opticall...A highly sensitive and selective electrochemical chiral sensor was developed based on the competitive supramolecular interaction of carbon nanofibers(CNFs)embedded sulfobutyl ether-b-cyclodextrin(SBEb-CD)with optically active cationic drugs at glassy carbon electrode(GCE).The difference in intermolecular hydrogen bonding/stability constant/enantioselectivity coefficient and Gibbs free energy of anionic host SBE-b-CD with enantiomers of amlodipine(R-/S-AML),clenbuterol(R-/S-CBL)and metoprolol(R-/S-MET)as a vip paved the way for efficient discrimination.The proposed sensing platform(CNFs-SBE-b-CD/GCE)could recognize the aforementioned enantiomers based on the discernible difference of peak potential(S/R-AML(△Ep=135 mV),R/S-MET(△Ep=99 mV)and R/S-CBL(△Ep=111 mV).The binding mechanisms and thermodynamic study of the enantiospecific behavior have been investigated using the host-vip chemistry approach inside the nanocavity and results suggest that S-AML,RMET,and R-CBL show stronger stability constants than their antipodes.Formation of the diastereomeric complex was taken as a measure of enantioselectivity and experimental results indicated that anionic SBE-b-CD is a better chiral ligand than neutral cyclodextrins.The fabricated sensor could be a useful lowcost electrochemical tool for molecular recognition of a variety of cationic species not only of drugs but also from other sources.展开更多
Constructed wetlands(CWs) are a promising method to treat effluent from wastewater treatment plants(WWTPs),However,low carbon/nitrogen(C/N) ratios of the influent inhibit denitrification in CWs,resulting in poor nitro...Constructed wetlands(CWs) are a promising method to treat effluent from wastewater treatment plants(WWTPs),However,low carbon/nitrogen(C/N) ratios of the influent inhibit denitrification in CWs,resulting in poor nitrogen removal efficiency.Herein,we compared traditional(control),biochar(BC), andβ-cyclodextrin-fu nctionalized biochar(BC@β-CD) CW systems to investigate nitrogen removal from influent with low C/N ratios,and the mechanisms that enhance this process.The highest nitrogen removal rates were observed in the BC@β-CD group,with rates 45.89% and 42.48% higher than those of the control,accompanied by a 70.57% and 85.45% decrease in nitrous oxide release,when the C/N ratio decreased from4 to 2,respectively.Metagenomic and enzymatic analyses indicated that BC@β-CD enhances nitrogen removal by coordinately promoting carbon metabolism and increasing denitrification enzyme activities,without affecting microbial species diversity in CWs.Structural equation modeling confirmed that the foremost advantages of BC@β-CD were effective electron generation and transportation resulting from increased activities of nicotinamide adenine dinucleotide(NADH) dehydrogenase and the electron transfer system(ETS),thereby strategically reallocating more carbon metabolic flow to support denitrification.Our results show that the application of BC@β-CD in CWs to optimize the reallocation of electrons from carbon metabolism is a feasible strategy to enhance denitrification under low C/N conditions.展开更多
Currently,simultaneous regulation of external morphology and internal electronic structure for Na_(3)V_(2)(PO_(4))_(3)(NVP)is rarely realized.Herein,complexes of β-cyclodextrin(βCD)and ethylenediaminetetraacetic aci...Currently,simultaneous regulation of external morphology and internal electronic structure for Na_(3)V_(2)(PO_(4))_(3)(NVP)is rarely realized.Herein,complexes of β-cyclodextrin(βCD)and ethylenediaminetetraacetic acid ferric sodium salt(EDTAFeNa)are utilized for the one-step preparation of NVP with spherical morphology as well as Fe substitution.βCD is initially hydrolyzed into glucose,and then carbon microspheres with numerous pores are formed through continuous dehydration and carbonization.The intermediate hydroxymethylfurfural is rich in active functional groups,which are attractive for the V/P-contained raw materials.Accordingly,the nucleation sites for NVP are successfully limited in the spherical framework,possessing a superior surface area of 97.15 g m^(-2).Furthermore,the beneficial Fe in EDTAFeNa enters into the NVP bulk to construct a novel Fe-doped Na_(3)V_(1.95)Fe_(0.05)(PO_(4))_(3)(NVP/β-ISC)material.Fe-substitution induces significant optimizations of electronic structure for NVP,which has been verified by the newly generated abundant oxygen vacancies and extended V-O bond length.Moreover,a multielectron reaction is activated,resulting from the V^(4+)/V^(5+)redox couple.The charge compensation mechanism of NVP/β-ISC is also deeply investigated.Density functional theory(DFT)calculations theoretically elaborate the mechanism of Fe-doping.Consequently,NVP/β-ISC reveals superior sodium storage performance in both half and full cells and even at different extreme conditions(needling,soaking,bending,and freezing).展开更多
A supramolecular nanoparticle that realized the loading and sustained release of ATP was successfully constructed from sulfato-b-cyclodextrin（SCD） and polyethylenimine（PEI）. The assembly and disassembly behaviors ...A supramolecular nanoparticle that realized the loading and sustained release of ATP was successfully constructed from sulfato-b-cyclodextrin（SCD） and polyethylenimine（PEI）. The assembly and disassembly behaviors of supramolecular nanoparticle were investigated by means of Tyndall effect,UV–vis spectroscopy, dynamic light scattering（DLS）, zeta potential and transmission electron microscopy（TEM）. Significantly, the resulting nanoparticle was disrupted with the increasing of p H and recovered to the spherical nanoparticle as the p H decreased to initial value. Owing to the positive zeta potential, the supramolecular nanoparticle showed the good loading and sustained release abilities towards ATP.展开更多
A novel 2,6-dimethyl-b-CD bonded and silica based HPLC chiral stationary phase（CSP） was prepared.The diphenylmethane diisocyanate（MDI） was applied for the first time in the immobilization of 2,6-dimethyl-b-CD onto...A novel 2,6-dimethyl-b-CD bonded and silica based HPLC chiral stationary phase（CSP） was prepared.The diphenylmethane diisocyanate（MDI） was applied for the first time in the immobilization of 2,6-dimethyl-b-CD onto the surface of aminized silica gel under mild conditions. The composite materials obtained were used as the CSP for chiral separation processes and this kind of CSP exhibits good enantioselectivity for a variety of chiral compounds under reversed-phase conditions.展开更多
文摘The inclusion complex of lappaconitine (Lap) with b-cyclodextrin (b-CD) has been studied by the differential scanning calorimetry (DSC) and 1H-NMR, 2D-NMR spectroscopy. The structure of the complex has been deduced.
文摘Using two b-cyclodextrin derivatives (CDs) with long chain of acyl groups as chiral stationary phases (CSPs) of capillary gas chromatography (CGC), the enantiomers of racemic allethrone and propargyllone were well resolved after derived with acetyl chloride. The enantiomer excess values (e.e.%) of 1S-allethrone and 1S-propargyllone were also determined successfully using these CDs.
基金supported by the National Natural Science Foundation of China(Grant Nos.51672098 and 51632001).
文摘A highly sensitive and selective electrochemical chiral sensor was developed based on the competitive supramolecular interaction of carbon nanofibers(CNFs)embedded sulfobutyl ether-b-cyclodextrin(SBEb-CD)with optically active cationic drugs at glassy carbon electrode(GCE).The difference in intermolecular hydrogen bonding/stability constant/enantioselectivity coefficient and Gibbs free energy of anionic host SBE-b-CD with enantiomers of amlodipine(R-/S-AML),clenbuterol(R-/S-CBL)and metoprolol(R-/S-MET)as a vip paved the way for efficient discrimination.The proposed sensing platform(CNFs-SBE-b-CD/GCE)could recognize the aforementioned enantiomers based on the discernible difference of peak potential(S/R-AML(△Ep=135 mV),R/S-MET(△Ep=99 mV)and R/S-CBL(△Ep=111 mV).The binding mechanisms and thermodynamic study of the enantiospecific behavior have been investigated using the host-vip chemistry approach inside the nanocavity and results suggest that S-AML,RMET,and R-CBL show stronger stability constants than their antipodes.Formation of the diastereomeric complex was taken as a measure of enantioselectivity and experimental results indicated that anionic SBE-b-CD is a better chiral ligand than neutral cyclodextrins.The fabricated sensor could be a useful lowcost electrochemical tool for molecular recognition of a variety of cationic species not only of drugs but also from other sources.
基金supported by the National Natural Science Foundation of China(52321005)the Guangdong Basic and Applied Basic Research Foundation(2023A1515012383 and 2024A1515030138)+1 种基金the State Key Laboratory of Urban Water Resource and Environment(Harbin Institute of Technology,2021TS30)the Shenzhen Science and Technology Program(KQTD20190929172630447 and KCXFZ20211020163404007).
文摘Constructed wetlands(CWs) are a promising method to treat effluent from wastewater treatment plants(WWTPs),However,low carbon/nitrogen(C/N) ratios of the influent inhibit denitrification in CWs,resulting in poor nitrogen removal efficiency.Herein,we compared traditional(control),biochar(BC), andβ-cyclodextrin-fu nctionalized biochar(BC@β-CD) CW systems to investigate nitrogen removal from influent with low C/N ratios,and the mechanisms that enhance this process.The highest nitrogen removal rates were observed in the BC@β-CD group,with rates 45.89% and 42.48% higher than those of the control,accompanied by a 70.57% and 85.45% decrease in nitrous oxide release,when the C/N ratio decreased from4 to 2,respectively.Metagenomic and enzymatic analyses indicated that BC@β-CD enhances nitrogen removal by coordinately promoting carbon metabolism and increasing denitrification enzyme activities,without affecting microbial species diversity in CWs.Structural equation modeling confirmed that the foremost advantages of BC@β-CD were effective electron generation and transportation resulting from increased activities of nicotinamide adenine dinucleotide(NADH) dehydrogenase and the electron transfer system(ETS),thereby strategically reallocating more carbon metabolic flow to support denitrification.Our results show that the application of BC@β-CD in CWs to optimize the reallocation of electrons from carbon metabolism is a feasible strategy to enhance denitrification under low C/N conditions.
基金financially supported by the Key Research and Development(R&D)Projects of Shanxi Province(202202040201005)the Graduate Innovation Project of Shanxi Province(No.2024SJ261)。
文摘Currently,simultaneous regulation of external morphology and internal electronic structure for Na_(3)V_(2)(PO_(4))_(3)(NVP)is rarely realized.Herein,complexes of β-cyclodextrin(βCD)and ethylenediaminetetraacetic acid ferric sodium salt(EDTAFeNa)are utilized for the one-step preparation of NVP with spherical morphology as well as Fe substitution.βCD is initially hydrolyzed into glucose,and then carbon microspheres with numerous pores are formed through continuous dehydration and carbonization.The intermediate hydroxymethylfurfural is rich in active functional groups,which are attractive for the V/P-contained raw materials.Accordingly,the nucleation sites for NVP are successfully limited in the spherical framework,possessing a superior surface area of 97.15 g m^(-2).Furthermore,the beneficial Fe in EDTAFeNa enters into the NVP bulk to construct a novel Fe-doped Na_(3)V_(1.95)Fe_(0.05)(PO_(4))_(3)(NVP/β-ISC)material.Fe-substitution induces significant optimizations of electronic structure for NVP,which has been verified by the newly generated abundant oxygen vacancies and extended V-O bond length.Moreover,a multielectron reaction is activated,resulting from the V^(4+)/V^(5+)redox couple.The charge compensation mechanism of NVP/β-ISC is also deeply investigated.Density functional theory(DFT)calculations theoretically elaborate the mechanism of Fe-doping.Consequently,NVP/β-ISC reveals superior sodium storage performance in both half and full cells and even at different extreme conditions(needling,soaking,bending,and freezing).
基金the National Natural Science Foundation of China (Nos. 21432004, 21672113, 21772099 and 91527301) for financial support
文摘A supramolecular nanoparticle that realized the loading and sustained release of ATP was successfully constructed from sulfato-b-cyclodextrin（SCD） and polyethylenimine（PEI）. The assembly and disassembly behaviors of supramolecular nanoparticle were investigated by means of Tyndall effect,UV–vis spectroscopy, dynamic light scattering（DLS）, zeta potential and transmission electron microscopy（TEM）. Significantly, the resulting nanoparticle was disrupted with the increasing of p H and recovered to the spherical nanoparticle as the p H decreased to initial value. Owing to the positive zeta potential, the supramolecular nanoparticle showed the good loading and sustained release abilities towards ATP.
文摘A novel 2,6-dimethyl-b-CD bonded and silica based HPLC chiral stationary phase（CSP） was prepared.The diphenylmethane diisocyanate（MDI） was applied for the first time in the immobilization of 2,6-dimethyl-b-CD onto the surface of aminized silica gel under mild conditions. The composite materials obtained were used as the CSP for chiral separation processes and this kind of CSP exhibits good enantioselectivity for a variety of chiral compounds under reversed-phase conditions.
