Short-term nitrous oxide（N2O） pulse emissions caused by precipitation account for a considerable portion of the annual N2O emissions and are greatly influenced by soil nitrogen（N） dynamics. However, in Chinese sem...Short-term nitrous oxide（N2O） pulse emissions caused by precipitation account for a considerable portion of the annual N2O emissions and are greatly influenced by soil nitrogen（N） dynamics. However, in Chinese semiarid temperate steppes, the response of N2O emissions to the coupling changes of precipitation and soil N availability is not yet fully understood. In this study, we conducted two 7-day field experiments in a semiarid temperate typical steppe of Inner Mongolia, China, to investigate the N2O emission pulses resulting from artificial precipitation events（approximately equivalent to 10.0 mm rainfall） under four N addition levels（0, 5, 10 and 20 g N/（m2·a）） using the static opaque chamber technique. The results show that the simulated rainfall during the dry period in 2010 caused greater short-term emission bursts than that during the relatively rainy observation period in 2011（P〈0.05）. No significant increase was observed for either the N2O peak effluxes or the weekly cumulative emissions（P〉0.05） with single water addition. The peak values of N2O efflux increased with the increasing N input. Only the treatments with water and medium（WN10） or high N addition（WN20） significantly increased the cumulative N2O emissions（P〈0.01） in both experimental periods. Under drought condition, the variations in soil N2O effluxes were positively correlated with the soil NH4-N concentrations in the three N input treatments（WN5, WN10, and WN20）. Besides, the soil moisture and temperature also greatly influenced the N2O pulse emissions, particularly the N2O pulse under the relatively rainy soil condition or in the treatments without N addition（ZN and ZWN）. The responses of the plant metabolism to the varying precipitation distribution and the length of drought period prior to rainfall could greatly affect the soil N dynamics and N2O emission pulses in semiarid grasslands.展开更多
The effect of incubation temperature and wet-dry cycle on the availabilities of Cd, Pb and Zn was studied. Three soils with pH ranging from 3.8 to 7.3, organic carbon （OC） from 0.7% to 2.4%, and clay from 12.3% to 3...The effect of incubation temperature and wet-dry cycle on the availabilities of Cd, Pb and Zn was studied. Three soils with pH ranging from 3.8 to 7.3, organic carbon （OC） from 0.7% to 2.4%, and clay from 12.3% to 35.6% were selected. Soils were spiked with reagent grade Cd（NO3）2, Pb（NO3）2, and Zn（NO3）2 at concentrations of 30 mg Cd/kg soil, 300 mg Zn/kg soil and 2000 mg Pb/kg soil. The soils were incubated at 35, 60, 105℃, respectively and went through four wet-dry cycles. Metal availability in soils was estimated by soil extraction with 0.1 mol/L Ca（NO3）2. According to this study, the effect of the spiking temperature on the metal availabilities was different among the metals, soils and wet-dry cycles. Mostly, 35 ~C was the first recommended spiking temperature for Cd and Pb while no spiking temperature was obviously better than others for Zn. Three wet-dry cycles was recommended regardless of the type of metals and incubation temperature.展开更多
A Markov repairable system with history-dependent up and down states is presented. The state space of the repairable system is divided into three sets, which are up states, down states and changeable states.Using aggr...A Markov repairable system with history-dependent up and down states is presented. The state space of the repairable system is divided into three sets, which are up states, down states and changeable states.Using aggregated stochastic processes, we can get the multi-interval availability and multi-point availability for the Markov repairable system. Finally, numerical examples are given to illustrate the obtained results.展开更多
Whilst phosphorus(P)in soil is considered to be abundant,the portion available for plant uptake constitutes less than 1%of the overall P present.To enhance crop productivity,the utilization of mineral P fertilizers ha...Whilst phosphorus(P)in soil is considered to be abundant,the portion available for plant uptake constitutes less than 1%of the overall P present.To enhance crop productivity,the utilization of mineral P fertilizers has become pervasive in agriculture.Nonetheless,the escalating prices of chemical fertilizers,coupled with new European regulations prohibiting the use of P fertilizers containing cadmium,have highlighted the urgency to identify environmentally friendly products and practices for P fertilization in agricultural soils.This comprehensive review delves into the current landscape of P fertilization from agricultural,political,and economic standpoints.We recognize the potential of microbes in mobilizing P,but emphasize the necessity for more robust research to establish their effectiveness in promoting plant P uptake under real-world conditions.Additionally,we explore the role of agricultural conservation practices,such as optimal tillage,diversified cropping systems,and increased organic carbon input,in conserving P.Furthermore,this review contemplates forthcoming innovations in research.These innovations encompass the development of enhanced formulations for biofertilizers and the undertaking of more comprehensive studies within the realm of conservation agriculture.All these endeavors collectively hold the potential to augment P accessibility to plants in a sustainable manner,thereby advancing agricultural sustainability and productivity.展开更多
We hereby comment on the interesting systematic review by Grewal et al where they have provided an overall picture of the current status of available tele-health programs in the United States with emphasis on the Amaz...We hereby comment on the interesting systematic review by Grewal et al where they have provided an overall picture of the current status of available tele-health programs in the United States with emphasis on the Amazon Clinic.Their analysis is an appreciable effort in discovering the features available and features lacking in these tele-health programs.The concept of tele-health originated to curtail the need for physical attendance of patients at health clinics,and has been beneficial during the coronavirus disease 2019 pandemic.We implore that the pearls and pitfalls of these programs have to be understood by policymakers prior to forming a consensus regarding the availability,accessibility and affordability of these programs as methods of healthcare delivery.Unrestricted proliferation of tele-health programs in their current form may pose threats to patient and provider safety and medicolegal liability.However,patients and providers must work together to improve them to meet their expectations and enable them to provide the best care for the ailing public.展开更多
Making plans is a good idea,but every one's schedule looks differe nt.You may have to talk about your plans before you're able to make some.It could sound like this:You ask,"Do you have plans this Friday ...Making plans is a good idea,but every one's schedule looks differe nt.You may have to talk about your plans before you're able to make some.It could sound like this:You ask,"Do you have plans this Friday night?"If the person already has plans,they may say,"I do.But I'm free on Saturday."If that day doesn't work for you,you can say,"I'm not available that day.How about Sunday after no on?"After you figure out the day and time,mark it on your calendar.展开更多
Natural phosphates(Apatite)are the main sources of phosphorus,one of the three major chemical elements for plant development.The present work aims to study the efficiency of dissolution of natural phosphate from Togo ...Natural phosphates(Apatite)are the main sources of phosphorus,one of the three major chemical elements for plant development.The present work aims to study the efficiency of dissolution of natural phosphate from Togo during composting of a mixture of this ore with different types of vegetal matter.Phospho-composts of mixtures of ore and cow dung(A+P),poultry droppings(B+P),nymphea(C+P),domestic organic waste(D+P)and vegetal organic composts without phosphate(A,B,C and D)were elaborated.Determination of available phosphorus concentrations by the colorimetry method(HACH DR 3800)in composts and phospho-composts was realized.Analysis results revealed that organic matter has a solubilizing effect on natural phosphate.Nymphea phospho-compost has the best ore dissolved because its assimilable phosphorus content is the highest(0.88%).These results also showed that phosphocomposts maturation time has a beneficial effect on the ore dissolution.展开更多
This study aims to explore the application of SysTrust Theory in Accounting Information Systems(AIS)through a systematic literature review.SysTrust Theory,developed by the AICPA(2017),focuses on the reliability of inf...This study aims to explore the application of SysTrust Theory in Accounting Information Systems(AIS)through a systematic literature review.SysTrust Theory,developed by the AICPA(2017),focuses on the reliability of information systems by assessing aspects such as availability,integrity,security,confidentiality,and privacy.This study analyzed several related articles published between 2012 and 2025,identifying the positive impacts of implementing SysTrust Theory on AIS effectiveness,business performance,financial reporting quality,and organizational commitment.The results showed that integrity was the most dominant factor in improving AIS reliability,followed by security and privacy.The implementation of SysTrust has also been shown to reduce the risk of fraud,improve the accuracy of financial data,and support strategic decision making.However,challenges such as user uncertainty about electronic payment systems and technology adaptation continue to be obstacles.This study recommends the need to improve system quality,educate users,and strengthen internal controls to optimize the benefits of SysTrust Theory in business practices.展开更多
This paper investigates the selective maintenance o systems that perform multi-mission in succession. Selective maintenance is performed on systems with limited break time to improve the success of the next mission. I...This paper investigates the selective maintenance o systems that perform multi-mission in succession. Selective maintenance is performed on systems with limited break time to improve the success of the next mission. In general, the duration of the mission is stochastic. However, existing studies rarely take into account system availability and the repairpersons with different skill levels. To solve this problem, a new multi-mission selective maintenance and repairpersons assignment model with stochastic duration of the mission are developed. To maximize the minimum phase-mission reliability while meeting the minimum system availability, the model is transformed into an optimization problem subject to limited maintenance resources. The optimization is then realized using an analytical method based on a self-programming function and a Monte Carlo simulation method, respectively. Finally, the validity of the model and solution method approaches are verified by numerical arithmetic examples. Comparative and sensitivity analyses are made to provide proven recommendations for decision-makers.展开更多
The behaviour of nanofertilizers(NFs)in plant-soil systems can differ from that of conventional chemical fertilizers due to their peculiar chemical-physical properties.Their effectiveness is still poorly understood.In...The behaviour of nanofertilizers(NFs)in plant-soil systems can differ from that of conventional chemical fertilizers due to their peculiar chemical-physical properties.Their effectiveness is still poorly understood.In this study,we evaluated the P fertilization potential of a novel nanosized FePO4NF(FePNF)in a plant-soil microcosm in a pot experiment.The efficacies of FePNF and a conventional P fertilizer(triple superphosphate,TSP)in sustaining the growth of cucumber plants were evaluated.Plants were grown for 28 d on a P-deficient soil,and determinations were made of plant growth parameters,mineral nutrient concentrations in plant tissues,P availability in soil,activities of soil enzymes involved in C,N,P,and S mineralization,and soil microbial community structure.No significant differences were found in plant dry weight,leaf area,chlorophyll content,or root growth between the FePNF and TSP treatments.Conversely,P availability in soil and P concentration in plant tissues at the end of the plant growth period were significantly higher after TSP fertilization compared to FePNF fertilization,whereas no significant differences were observed for other nutrients.Among the measured soil enzyme activities,there were no significant differences in the activities of soil acid phosphatase,β-glucosidase,and arylsulfatase between the FePNF and TSP treatments,while soil alkaline phosphatase activity was higher in the TSP treatment than in the FePNF treatment and the protease activity was higher in the FePNF treatment than in the TSP treatment.The FePNF and TSP treatments showed significant differences in soil archaeal,bacterial,and fungal community structures,although the microbial community profiles generally clustered closer to each other in the two treatments.We concluded that FePNF can be an efficient alternative to the conventional P fertilizer TSP.展开更多
Humic acid(HA)prevents phosphorus(P)fixation and promotes P absorption by plants,thereby effectively increasing the efficiency of phosphate fertiliser utilisation.Although nano-sized HA(NHA)might exhibit superior effe...Humic acid(HA)prevents phosphorus(P)fixation and promotes P absorption by plants,thereby effectively increasing the efficiency of phosphate fertiliser utilisation.Although nano-sized HA(NHA)might exhibit superior effects compared to conventional-sized HA(CHA),evidence is limited.Therefore,we investigated the effects of CHA and NHA applied with conventional phosphate fertiliser(CHA+CP and NHA+CP,respectively)on chilli pepper biomass,P uptake,and root morphology,as well as soil available P content,and evaluated CHA,NHA,and their residues in the soil for differences in specific surface area,functional groups,molecular weight distribution,and surface elemental compositions in a 40-d pot cultivation experiment.Results showed that the CHA+CP and NHA+CP treatments significantly increased pepper biomass and P uptake by 15.2%–24.7%and 37.9%–49.0%,respectively,compared to the conventional phosphate fertiliser applied alone(CP)treatment(P<0.05),with NHA exhibiting a greater effect than CHA.This was primarily related to NHA's stronger ability to reduce P fixation than that of CHA.Soil available P content significantly increased by 5.8%and 3.8%in the NHA+CP treatment compared with CHA+CP on days 22 and 40 of cultivation,respectively(P<0.05).Nano-sized HA contained more small-molecule components and carboxyl groups than CHA,which can more stimulate root elongation and thus promote root P uptake.Furthermore,fertiliser-derived P gradually entered the structure of CHA or NHA during cultivation.The presence of more plant-available forms(e.g.,H2PO_(4)^(2-)and HPO_(4)^(2-))in NHA compared to CHA also contributed to better regulation of phosphate fertiliser efficacy.In conclusion,NHA is superior to CHA in improving phosphate fertiliser efficiency,making it a potential alternative material for the development of high-efficiency phosphate fertilisers.This presents an excellent opportunity to minimise P resource waste.展开更多
In this paper,the topological structure of the vehicle wireless network M2M(Machine to Machine)is used as the experimental research model,and four kinds of light coefficients are set as factors affecting the experimen...In this paper,the topological structure of the vehicle wireless network M2M(Machine to Machine)is used as the experimental research model,and four kinds of light coefficients are set as factors affecting the experimental results,namely,light intensity factor ∈ and α,to represent the light intensity coefficient and influence factor.The remaining energy consumption of mobile terminal equipment was measured respectively,the distance parameter from device to device,the maximum transmission energy consumption,and the correlation coefficient between environmental parameters and energy consumption parameters was analyzed.This paper discusses the impact of different topological structures on the environment,energy saving and emission reduction in the relatively flat terrain area,based on the planning scheme of parking area within the coverage range of base station signal,the transmission capability of vehicles as mobile device nodes within the coverage range of base station signal,and the signal coverage range of base station under different light intensity.As the distance between the base station and the vehicle mobile device node changes,the maximum transmission energy consumption of the mobile device node is obtained.Based on the above factors,the optimal performance optimization parking scheme and the optimal energy consumption optimization transmission scheme are obtained.展开更多
phoD and pqqC gene occurrence in bacteria allows them to mobilize phosphorus(P)by mineralizing organic P(Po)and solubilizing inorganic P(Pi),respectively.Community characteristics of phoD-and pqqC-harboring bacteria(p...phoD and pqqC gene occurrence in bacteria allows them to mobilize phosphorus(P)by mineralizing organic P(Po)and solubilizing inorganic P(Pi),respectively.Community characteristics of phoD-and pqqC-harboring bacteria(phoD-and pqqC-HB,respectively)mediate P cycling.However,whether the microbial community assembly and keystone taxa of phoD-and pqqC-HB regulate P availability and distinct regulatory pathways between these two genes remain unclear.In this study,soil microbial community characteristics and P availability were investigated in four long-term(38-year)fertilization regimes:control with no fertilizer(CK),P fertilizer(PF),nitrogen(N)and P fertilizers(NP),and N fertilizer,P fertilizer,and manure(NPM).The N addition treatments(NP and NPM)significantly changed the community composition and increased the abundances of phoD-and pqqC-HB compared to the no-N addition treatments(CK and PF).Stochastic processes dominated the community assembly of both phoD-and pqqC-HB,and the relative contributions of stochasticity increased with N addition.Furthermore,the N addition treatments resulted in greater network complexity and higher abundances of keystone taxa of phoD-and pqqC-HB compared to those of the no-N addition treatments.The keystone taxa implicated in P cycling were also associated with carbon(C)and N cycling processes.Microbial community composition and assembly processes were the main factors driving labile Pi for phoD-HB,whereas keystone taxa contributed the most to labile Pi for pqqC-HB.These results emphasize that distinct mechanisms of phoD-and pqqC-HB regulate P availability under fertilization management and underline the significance of microbial community assembly and keystone taxa in soil ecological functions,offering fresh perspectives on comprehending the biological processes facilitated by microorganisms in enhancing soil quality.展开更多
This research directly supported the author’s thesis work in partial fulfilment of Master of Science in biology from the University of North Texas(United States)from August 1996 to September 1997.Two sites at Lake Ra...This research directly supported the author’s thesis work in partial fulfilment of Master of Science in biology from the University of North Texas(United States)from August 1996 to September 1997.Two sites at Lake Ray Roberts,Denton County,Texas(United States)were examined and contrasted for productivity.The site located in the pelagic zone exhibited a slight,thermal gradient with no stratification,and a slightly stratified clinograde oxygen profile which is typical for summer-stratified eutrophic lakes.The site located in the shallow,littoral zone exhibited high,increasing turbidity with depth,marked by shallow light attenuation through the water column.Temperature was constant at every depth in the littoral site,with a slight,clinograde oxygen profile,typical for shallow,littoral areas subject to wind-induced mixing.Volume estimations of chlorophyll-α shows a strong presence in the euphotic zone,indicating photosynthesis occurs until approximately 2.2 m below the surface.The shallow,littoral site showed the basic signs of higher productivity than the open,pelagic site.展开更多
Heart transplantation is a life-saving procedure for many people throughout the world.Data shows that in 2024,there was an increase in the volume of adult heart transplantation in the United States even as there was a...Heart transplantation is a life-saving procedure for many people throughout the world.Data shows that in 2024,there was an increase in the volume of adult heart transplantation in the United States even as there was a decrease in the volume of pediatric heart transplantation to the lowest volume in a decade.Organ availability remains a major limiting factor affecting transplant volume.This mandates that innovation must take place to increase the supply of donor organs.While some strategies such as donation after cardiac death,hepatitis C virus+transplantation,and ABO-incompatible transplantation have increased the pool for donation,it still falls short of meeting the demand.Other proposed strategies include splitting the donor heart to provide multiple partial heart transplants,domino partial heart transplantation,changes in legislation including opt-out legislation,and xenotransplantation.Further evolution and refinement of these strategies will make a meaningful impact on patients awaiting life-saving heart transplants.展开更多
Plant roots and microorganisms are integral to the phosphorus(P)transformation process in forest soils.However,the specific mechanisms by which they affect soil P availability under long-term nitrogen(N)addition remai...Plant roots and microorganisms are integral to the phosphorus(P)transformation process in forest soils.However,the specific mechanisms by which they affect soil P availability under long-term nitrogen(N)addition remain elusive.Therefore,a long-term N addition experiment was conducted in a temperate forest in China.After 11-year N addition,measurements focused on P fractions,soil microbial biomass(SMB),microbial community(PLFAs),phosphatase activity,fine root biomass(FRB),and fine root biomass P(FRBP).The results demonstrated that N addition significantly decreased Resin-P and total extractable organic P(Po),while having no significant effect on total extractable inorganic P(Pi).Moreover,a strong positive correlation was observed between Resin-P and total extractable Po,suggesting that under N addition,organic P serves as the primary source of soluble P.This implies that continuous N deposition may exhaust the potential P source stored as organic P in forest soils.N addition also led to a reduction in SMB and FRB.Notably,microbial biomass P and FRBP were positively correlated with Resin-P and total extractable Po,indicating that the decrease in SMB and FRB is the main contributor to the decline in soluble P and organic P.Additionally,N addition significantly reduced phosphatase activity,suggesting an inhibition of the organic P hydrolysis process.In conclusion,N addition decreases P input into the soil by reducing SMB and FRB,and inhibits the transformation of different P forms by lowering enzyme activity.Consequently,soil organic P and soluble P decline,further intensifying P limitation.展开更多
The Reference Listed drug(RLD)plays a critical role in the development and research of generic medicinal products,serving as the comparator product used in the marketing authorization application of new generic medici...The Reference Listed drug(RLD)plays a critical role in the development and research of generic medicinal products,serving as the comparator product used in the marketing authorization application of new generic medicinal product and re-evaluation of generic medicinal product.In China,RLDs are sourced from various origins,but their quality and market availability can be constrained by multiple factors,including emergent issues such as nitrosamine impurities.Five classes of medicinal products have been reported to be at risk for containing nitrosamine impurities:sartan-based medicines,metformin-containing products,ranitidine medicines,rifampicin medicines,and Champix.This paper explores the control strategies implemented by drug regulatory agencies in the United States and the European Union to manage nitrosamine impurities and assesses their impact on the market availability and quality of RLDs in China.The aim is to offer valuable insights for generic drug manufacturers and regulatory bodies both domestically and internationally.展开更多
Antibodies currently comprise the predominant treatment modality for a variety of diseases;therefore,optimizing their properties rapidly and efficiently is an indispensable step in antibody-based drug development.Insp...Antibodies currently comprise the predominant treatment modality for a variety of diseases;therefore,optimizing their properties rapidly and efficiently is an indispensable step in antibody-based drug development.Inspired by the great success of artificial intelligence-based algorithms,especially deep learning-based methods in the field of biology,various computational methods have been introduced into antibody optimization to reduce costs and increase the success rate of lead candidate generation and optimization.Herein,we briefly review recent progress in deep learning-based antibody optimization,focusing on the available datasets and algorithm input data types that are crucial for constructing appropriate deep learning models.Furthermore,we discuss the current challenges and potential solutions for the future development of general-purpose deep learning algorithms in antibody optimization.展开更多
The oceanic general circulations in the Ross Sea,where the southernmost ocean is located,play an important role in the climate system.Yet,the energy cycle of oceanic circulations in the Ross Sea is still unclear.By em...The oceanic general circulations in the Ross Sea,where the southernmost ocean is located,play an important role in the climate system.Yet,the energy cycle of oceanic circulations in the Ross Sea is still unclear.By employing an eddypermitting coupled regional ocean-sea ice-ice shelf model,this study investigates the oceanic energy cycle in the Ross Sea.Based on the Lorenz Energy Cycle framework,the spatiotemporal distributions of kinetic energy and available potential energy within the Ross Sea are quantitatively analyzed.The power pathways and magnitudes of energy conversion are also quantified.The simulated results show that the Mean Available Potential Energy(MAPE)is the largest energy reservoir of about 527.62 PJ(1 PJ=10^(15) J),followed by the Eddy Available Potential Energy(EAPE),the Mean Kinetic Energy(MKE),and the Eddy Kinetic Energy(EKE)of about 19.20 PJ,1.04 PJ,and 0.82 PJ,respectively.In the sub-ice-shelf cavity,the maximal MAPE is up to about 177.81 PJ,and the EAPE,MKE,and EKE are about 2.58 PJ,39.87 TJ(1 TJ=10^(12) J),and 23.05 TJ,respectively.The inputs to the regional energy reservoirs are mainly from the sea surface momentum and buoyancy fluxes.The baroclinic pathway plays a dominant role in the conversion of energy to EKE,both in the open ocean and in the sub-ice-shelf cavity.The energy conversion from EAPE to EKE in the open ocean and the sub-ice-shelf cavity is about 2.86 GW(1 GW=10^(9) J)and 162.18 MW(1 MW=10^(6) J),respectively.In addition,the kinetic energy is directed from EKE to MKE in the Ross Sea,and such an energy flow in the barotropic pathway is opposite from that in the Southern Ocean.展开更多
The traditional nanozymes-based ratiometric fluorescence sensing platforms usually necessitate the supplementary addition of fluorescent probes,therefore greatly restricting its convenient and broad application.In thi...The traditional nanozymes-based ratiometric fluorescence sensing platforms usually necessitate the supplementary addition of fluorescent probes,therefore greatly restricting its convenient and broad application.In this study,a highly sensitive and selective ratiometric fluorescence platform for alkaline phosphatase(ALP)detection was established,only employing Prussian blue(PB)nanozymes and a commercially available chromogen of o-phenylenediamine(OPD).PB nanozymes with remarkable peroxidaselike(POD-like)activity can effectively catalyze OPD chromogen to yield 2,3-diaminophenazine(OPDox)with an intense yellow fluorescence at 573 nm emission peak.Target ALP can facilitate ascorbic acid 2-phosphate(AAP)dephosphorylation to generate phosphate and ascorbic acid(AA).Significantly,both these two resultant hydrolysis products could effectively decrease the OPDox generation via a dualpath based inhibition on the PB nanozymes POD-like activity.On the other hand,the generated dehydroascorbic acid(DHAA)from AA oxidation would exclusively react with OPD chromogen to yield3-(dihydroxyethyl)furo[3,4-b]quinoxaline-1-one(DFQ)with a strong blue fluorescent signal at 434nm,which further providing a significant enhancement on the sensing selectivity of ALP detection.As a result,an increased yellow fluorescence of OPDox and decreased blue fluorescence of DFQ could be clearly observed with different ALP addition.A robust linear relationship between the fluorescence ratio of F_(434)/F_(573)and ALP activity ranging from 0.25U/L to 6U/L was obtained,with a low detection limit of 0.112 U/L.This proposed method demonstrates high sensitivity,excellent selectivity,cost-effectiveness,and operational simplicity,yet enabling an effective detection of ALP levels in human serum.展开更多
基金founded by the Knowledge Innovation Program of Chinese Academy of Sciences (KZCX2-EW-302)the National Natural Science Foundation of China (41073061, 41330528, 41203054)
文摘Short-term nitrous oxide（N2O） pulse emissions caused by precipitation account for a considerable portion of the annual N2O emissions and are greatly influenced by soil nitrogen（N） dynamics. However, in Chinese semiarid temperate steppes, the response of N2O emissions to the coupling changes of precipitation and soil N availability is not yet fully understood. In this study, we conducted two 7-day field experiments in a semiarid temperate typical steppe of Inner Mongolia, China, to investigate the N2O emission pulses resulting from artificial precipitation events（approximately equivalent to 10.0 mm rainfall） under four N addition levels（0, 5, 10 and 20 g N/（m2·a）） using the static opaque chamber technique. The results show that the simulated rainfall during the dry period in 2010 caused greater short-term emission bursts than that during the relatively rainy observation period in 2011（P〈0.05）. No significant increase was observed for either the N2O peak effluxes or the weekly cumulative emissions（P〉0.05） with single water addition. The peak values of N2O efflux increased with the increasing N input. Only the treatments with water and medium（WN10） or high N addition（WN20） significantly increased the cumulative N2O emissions（P〈0.01） in both experimental periods. Under drought condition, the variations in soil N2O effluxes were positively correlated with the soil NH4-N concentrations in the three N input treatments（WN5, WN10, and WN20）. Besides, the soil moisture and temperature also greatly influenced the N2O pulse emissions, particularly the N2O pulse under the relatively rainy soil condition or in the treatments without N addition（ZN and ZWN）. The responses of the plant metabolism to the varying precipitation distribution and the length of drought period prior to rainfall could greatly affect the soil N dynamics and N2O emission pulses in semiarid grasslands.
基金The Strategic Environment Research and Development Program, USA and Alcoa Foundation "Sustainable Development of RuralArea in China"
文摘The effect of incubation temperature and wet-dry cycle on the availabilities of Cd, Pb and Zn was studied. Three soils with pH ranging from 3.8 to 7.3, organic carbon （OC） from 0.7% to 2.4%, and clay from 12.3% to 35.6% were selected. Soils were spiked with reagent grade Cd（NO3）2, Pb（NO3）2, and Zn（NO3）2 at concentrations of 30 mg Cd/kg soil, 300 mg Zn/kg soil and 2000 mg Pb/kg soil. The soils were incubated at 35, 60, 105℃, respectively and went through four wet-dry cycles. Metal availability in soils was estimated by soil extraction with 0.1 mol/L Ca（NO3）2. According to this study, the effect of the spiking temperature on the metal availabilities was different among the metals, soils and wet-dry cycles. Mostly, 35 ~C was the first recommended spiking temperature for Cd and Pb while no spiking temperature was obviously better than others for Zn. Three wet-dry cycles was recommended regardless of the type of metals and incubation temperature.
基金the National Natural Science Foundation of China(No.71371031)
文摘A Markov repairable system with history-dependent up and down states is presented. The state space of the repairable system is divided into three sets, which are up states, down states and changeable states.Using aggregated stochastic processes, we can get the multi-interval availability and multi-point availability for the Markov repairable system. Finally, numerical examples are given to illustrate the obtained results.
基金financed by the Spanish Ministry of Science and Innovation and the European Regional Development Fund(ERDF)(No.PID20211234690BI00)the European Joint Program EJP_Soil(TRACE-Soils)(No.862695)+1 种基金the Spanish Ministry of Science and Innovation(RED2018-102624TMCIN/AEI/10.13039/501100011033)the Project PREPSOIL European Union(No.101070045,HORIZON CSA)。
文摘Whilst phosphorus(P)in soil is considered to be abundant,the portion available for plant uptake constitutes less than 1%of the overall P present.To enhance crop productivity,the utilization of mineral P fertilizers has become pervasive in agriculture.Nonetheless,the escalating prices of chemical fertilizers,coupled with new European regulations prohibiting the use of P fertilizers containing cadmium,have highlighted the urgency to identify environmentally friendly products and practices for P fertilization in agricultural soils.This comprehensive review delves into the current landscape of P fertilization from agricultural,political,and economic standpoints.We recognize the potential of microbes in mobilizing P,but emphasize the necessity for more robust research to establish their effectiveness in promoting plant P uptake under real-world conditions.Additionally,we explore the role of agricultural conservation practices,such as optimal tillage,diversified cropping systems,and increased organic carbon input,in conserving P.Furthermore,this review contemplates forthcoming innovations in research.These innovations encompass the development of enhanced formulations for biofertilizers and the undertaking of more comprehensive studies within the realm of conservation agriculture.All these endeavors collectively hold the potential to augment P accessibility to plants in a sustainable manner,thereby advancing agricultural sustainability and productivity.
文摘We hereby comment on the interesting systematic review by Grewal et al where they have provided an overall picture of the current status of available tele-health programs in the United States with emphasis on the Amazon Clinic.Their analysis is an appreciable effort in discovering the features available and features lacking in these tele-health programs.The concept of tele-health originated to curtail the need for physical attendance of patients at health clinics,and has been beneficial during the coronavirus disease 2019 pandemic.We implore that the pearls and pitfalls of these programs have to be understood by policymakers prior to forming a consensus regarding the availability,accessibility and affordability of these programs as methods of healthcare delivery.Unrestricted proliferation of tele-health programs in their current form may pose threats to patient and provider safety and medicolegal liability.However,patients and providers must work together to improve them to meet their expectations and enable them to provide the best care for the ailing public.
文摘Making plans is a good idea,but every one's schedule looks differe nt.You may have to talk about your plans before you're able to make some.It could sound like this:You ask,"Do you have plans this Friday night?"If the person already has plans,they may say,"I do.But I'm free on Saturday."If that day doesn't work for you,you can say,"I'm not available that day.How about Sunday after no on?"After you figure out the day and time,mark it on your calendar.
基金SIGMA Scientific Group and Mohamed VI Polytechnic University for their financial support.
文摘Natural phosphates(Apatite)are the main sources of phosphorus,one of the three major chemical elements for plant development.The present work aims to study the efficiency of dissolution of natural phosphate from Togo during composting of a mixture of this ore with different types of vegetal matter.Phospho-composts of mixtures of ore and cow dung(A+P),poultry droppings(B+P),nymphea(C+P),domestic organic waste(D+P)and vegetal organic composts without phosphate(A,B,C and D)were elaborated.Determination of available phosphorus concentrations by the colorimetry method(HACH DR 3800)in composts and phospho-composts was realized.Analysis results revealed that organic matter has a solubilizing effect on natural phosphate.Nymphea phospho-compost has the best ore dissolved because its assimilable phosphorus content is the highest(0.88%).These results also showed that phosphocomposts maturation time has a beneficial effect on the ore dissolution.
文摘This study aims to explore the application of SysTrust Theory in Accounting Information Systems(AIS)through a systematic literature review.SysTrust Theory,developed by the AICPA(2017),focuses on the reliability of information systems by assessing aspects such as availability,integrity,security,confidentiality,and privacy.This study analyzed several related articles published between 2012 and 2025,identifying the positive impacts of implementing SysTrust Theory on AIS effectiveness,business performance,financial reporting quality,and organizational commitment.The results showed that integrity was the most dominant factor in improving AIS reliability,followed by security and privacy.The implementation of SysTrust has also been shown to reduce the risk of fraud,improve the accuracy of financial data,and support strategic decision making.However,challenges such as user uncertainty about electronic payment systems and technology adaptation continue to be obstacles.This study recommends the need to improve system quality,educate users,and strengthen internal controls to optimize the benefits of SysTrust Theory in business practices.
文摘This paper investigates the selective maintenance o systems that perform multi-mission in succession. Selective maintenance is performed on systems with limited break time to improve the success of the next mission. In general, the duration of the mission is stochastic. However, existing studies rarely take into account system availability and the repairpersons with different skill levels. To solve this problem, a new multi-mission selective maintenance and repairpersons assignment model with stochastic duration of the mission are developed. To maximize the minimum phase-mission reliability while meeting the minimum system availability, the model is transformed into an optimization problem subject to limited maintenance resources. The optimization is then realized using an analytical method based on a self-programming function and a Monte Carlo simulation method, respectively. Finally, the validity of the model and solution method approaches are verified by numerical arithmetic examples. Comparative and sensitivity analyses are made to provide proven recommendations for decision-makers.
基金supported by the Joint Project 2016 and the Joint Project 2019,developed by the University of Verona and Fabbrica Cooperativa Perfosfati Cerea,Italy。
文摘The behaviour of nanofertilizers(NFs)in plant-soil systems can differ from that of conventional chemical fertilizers due to their peculiar chemical-physical properties.Their effectiveness is still poorly understood.In this study,we evaluated the P fertilization potential of a novel nanosized FePO4NF(FePNF)in a plant-soil microcosm in a pot experiment.The efficacies of FePNF and a conventional P fertilizer(triple superphosphate,TSP)in sustaining the growth of cucumber plants were evaluated.Plants were grown for 28 d on a P-deficient soil,and determinations were made of plant growth parameters,mineral nutrient concentrations in plant tissues,P availability in soil,activities of soil enzymes involved in C,N,P,and S mineralization,and soil microbial community structure.No significant differences were found in plant dry weight,leaf area,chlorophyll content,or root growth between the FePNF and TSP treatments.Conversely,P availability in soil and P concentration in plant tissues at the end of the plant growth period were significantly higher after TSP fertilization compared to FePNF fertilization,whereas no significant differences were observed for other nutrients.Among the measured soil enzyme activities,there were no significant differences in the activities of soil acid phosphatase,β-glucosidase,and arylsulfatase between the FePNF and TSP treatments,while soil alkaline phosphatase activity was higher in the TSP treatment than in the FePNF treatment and the protease activity was higher in the FePNF treatment than in the TSP treatment.The FePNF and TSP treatments showed significant differences in soil archaeal,bacterial,and fungal community structures,although the microbial community profiles generally clustered closer to each other in the two treatments.We concluded that FePNF can be an efficient alternative to the conventional P fertilizer TSP.
基金supported by the National Key R&D Program of China during the 14th Five-Year Plan period(No.2023YFD1700205)the National Natural Science Foundation of China(No.32402678)+4 种基金the Anhui Provincial Department of Education Research Project(No.2024AH05045)the Science Foundation for Youth of Anhui Province of China(No.1908085QC139),the Major Science and Technology in Anhui Province of China(No.202103a06020012)the Science Foundation for Distinguished Youth of Anhui Province of China(No.2008085J13)the Key Project of Educational Commission of Anhui Province of China(No.2022AH050886)the Key Project of Youth Fund of Anhui Agricultural University of China(No.2018zd25).
文摘Humic acid(HA)prevents phosphorus(P)fixation and promotes P absorption by plants,thereby effectively increasing the efficiency of phosphate fertiliser utilisation.Although nano-sized HA(NHA)might exhibit superior effects compared to conventional-sized HA(CHA),evidence is limited.Therefore,we investigated the effects of CHA and NHA applied with conventional phosphate fertiliser(CHA+CP and NHA+CP,respectively)on chilli pepper biomass,P uptake,and root morphology,as well as soil available P content,and evaluated CHA,NHA,and their residues in the soil for differences in specific surface area,functional groups,molecular weight distribution,and surface elemental compositions in a 40-d pot cultivation experiment.Results showed that the CHA+CP and NHA+CP treatments significantly increased pepper biomass and P uptake by 15.2%–24.7%and 37.9%–49.0%,respectively,compared to the conventional phosphate fertiliser applied alone(CP)treatment(P<0.05),with NHA exhibiting a greater effect than CHA.This was primarily related to NHA's stronger ability to reduce P fixation than that of CHA.Soil available P content significantly increased by 5.8%and 3.8%in the NHA+CP treatment compared with CHA+CP on days 22 and 40 of cultivation,respectively(P<0.05).Nano-sized HA contained more small-molecule components and carboxyl groups than CHA,which can more stimulate root elongation and thus promote root P uptake.Furthermore,fertiliser-derived P gradually entered the structure of CHA or NHA during cultivation.The presence of more plant-available forms(e.g.,H2PO_(4)^(2-)and HPO_(4)^(2-))in NHA compared to CHA also contributed to better regulation of phosphate fertiliser efficacy.In conclusion,NHA is superior to CHA in improving phosphate fertiliser efficiency,making it a potential alternative material for the development of high-efficiency phosphate fertilisers.This presents an excellent opportunity to minimise P resource waste.
文摘In this paper,the topological structure of the vehicle wireless network M2M(Machine to Machine)is used as the experimental research model,and four kinds of light coefficients are set as factors affecting the experimental results,namely,light intensity factor ∈ and α,to represent the light intensity coefficient and influence factor.The remaining energy consumption of mobile terminal equipment was measured respectively,the distance parameter from device to device,the maximum transmission energy consumption,and the correlation coefficient between environmental parameters and energy consumption parameters was analyzed.This paper discusses the impact of different topological structures on the environment,energy saving and emission reduction in the relatively flat terrain area,based on the planning scheme of parking area within the coverage range of base station signal,the transmission capability of vehicles as mobile device nodes within the coverage range of base station signal,and the signal coverage range of base station under different light intensity.As the distance between the base station and the vehicle mobile device node changes,the maximum transmission energy consumption of the mobile device node is obtained.Based on the above factors,the optimal performance optimization parking scheme and the optimal energy consumption optimization transmission scheme are obtained.
基金supported by the National Key Research and Development Program of China(No.2022YFD 1901601)the National Natural Science Foundation of China(No.42107360)the Fundamental Research Funds for the Central Universities,China(No.2452021032).
文摘phoD and pqqC gene occurrence in bacteria allows them to mobilize phosphorus(P)by mineralizing organic P(Po)and solubilizing inorganic P(Pi),respectively.Community characteristics of phoD-and pqqC-harboring bacteria(phoD-and pqqC-HB,respectively)mediate P cycling.However,whether the microbial community assembly and keystone taxa of phoD-and pqqC-HB regulate P availability and distinct regulatory pathways between these two genes remain unclear.In this study,soil microbial community characteristics and P availability were investigated in four long-term(38-year)fertilization regimes:control with no fertilizer(CK),P fertilizer(PF),nitrogen(N)and P fertilizers(NP),and N fertilizer,P fertilizer,and manure(NPM).The N addition treatments(NP and NPM)significantly changed the community composition and increased the abundances of phoD-and pqqC-HB compared to the no-N addition treatments(CK and PF).Stochastic processes dominated the community assembly of both phoD-and pqqC-HB,and the relative contributions of stochasticity increased with N addition.Furthermore,the N addition treatments resulted in greater network complexity and higher abundances of keystone taxa of phoD-and pqqC-HB compared to those of the no-N addition treatments.The keystone taxa implicated in P cycling were also associated with carbon(C)and N cycling processes.Microbial community composition and assembly processes were the main factors driving labile Pi for phoD-HB,whereas keystone taxa contributed the most to labile Pi for pqqC-HB.These results emphasize that distinct mechanisms of phoD-and pqqC-HB regulate P availability under fertilization management and underline the significance of microbial community assembly and keystone taxa in soil ecological functions,offering fresh perspectives on comprehending the biological processes facilitated by microorganisms in enhancing soil quality.
文摘This research directly supported the author’s thesis work in partial fulfilment of Master of Science in biology from the University of North Texas(United States)from August 1996 to September 1997.Two sites at Lake Ray Roberts,Denton County,Texas(United States)were examined and contrasted for productivity.The site located in the pelagic zone exhibited a slight,thermal gradient with no stratification,and a slightly stratified clinograde oxygen profile which is typical for summer-stratified eutrophic lakes.The site located in the shallow,littoral zone exhibited high,increasing turbidity with depth,marked by shallow light attenuation through the water column.Temperature was constant at every depth in the littoral site,with a slight,clinograde oxygen profile,typical for shallow,littoral areas subject to wind-induced mixing.Volume estimations of chlorophyll-α shows a strong presence in the euphotic zone,indicating photosynthesis occurs until approximately 2.2 m below the surface.The shallow,littoral site showed the basic signs of higher productivity than the open,pelagic site.
文摘Heart transplantation is a life-saving procedure for many people throughout the world.Data shows that in 2024,there was an increase in the volume of adult heart transplantation in the United States even as there was a decrease in the volume of pediatric heart transplantation to the lowest volume in a decade.Organ availability remains a major limiting factor affecting transplant volume.This mandates that innovation must take place to increase the supply of donor organs.While some strategies such as donation after cardiac death,hepatitis C virus+transplantation,and ABO-incompatible transplantation have increased the pool for donation,it still falls short of meeting the demand.Other proposed strategies include splitting the donor heart to provide multiple partial heart transplants,domino partial heart transplantation,changes in legislation including opt-out legislation,and xenotransplantation.Further evolution and refinement of these strategies will make a meaningful impact on patients awaiting life-saving heart transplants.
基金supported by the Key Research Program Foundation of Higher Education in Henan Province(Grant No.24A180027)the China Postdoctoral Science Foundation(Grant No.2023M741727)+2 种基金the Xinyang Academy of Ecological Research Open Foundation(Grant No.2023XYQN14)the Postdoctoral Science Foundation of Henan Province(Grant No.202103058)the Major Applied Research Program in Humanities and Social Sciences of Henan Provincial Education Department(Grant No.2022-YYZD-22).
文摘Plant roots and microorganisms are integral to the phosphorus(P)transformation process in forest soils.However,the specific mechanisms by which they affect soil P availability under long-term nitrogen(N)addition remain elusive.Therefore,a long-term N addition experiment was conducted in a temperate forest in China.After 11-year N addition,measurements focused on P fractions,soil microbial biomass(SMB),microbial community(PLFAs),phosphatase activity,fine root biomass(FRB),and fine root biomass P(FRBP).The results demonstrated that N addition significantly decreased Resin-P and total extractable organic P(Po),while having no significant effect on total extractable inorganic P(Pi).Moreover,a strong positive correlation was observed between Resin-P and total extractable Po,suggesting that under N addition,organic P serves as the primary source of soluble P.This implies that continuous N deposition may exhaust the potential P source stored as organic P in forest soils.N addition also led to a reduction in SMB and FRB.Notably,microbial biomass P and FRBP were positively correlated with Resin-P and total extractable Po,indicating that the decrease in SMB and FRB is the main contributor to the decline in soluble P and organic P.Additionally,N addition significantly reduced phosphatase activity,suggesting an inhibition of the organic P hydrolysis process.In conclusion,N addition decreases P input into the soil by reducing SMB and FRB,and inhibits the transformation of different P forms by lowering enzyme activity.Consequently,soil organic P and soluble P decline,further intensifying P limitation.
基金Subject construction funding project of Institute for Chemical Drug Control(Grant No.2024HYZX42)in National Institutes for Food and Drug Control,Beijing,China。
文摘The Reference Listed drug(RLD)plays a critical role in the development and research of generic medicinal products,serving as the comparator product used in the marketing authorization application of new generic medicinal product and re-evaluation of generic medicinal product.In China,RLDs are sourced from various origins,but their quality and market availability can be constrained by multiple factors,including emergent issues such as nitrosamine impurities.Five classes of medicinal products have been reported to be at risk for containing nitrosamine impurities:sartan-based medicines,metformin-containing products,ranitidine medicines,rifampicin medicines,and Champix.This paper explores the control strategies implemented by drug regulatory agencies in the United States and the European Union to manage nitrosamine impurities and assesses their impact on the market availability and quality of RLDs in China.The aim is to offer valuable insights for generic drug manufacturers and regulatory bodies both domestically and internationally.
基金supported by the National Natural Science Foundation of China(No.12104396)the National Key R&D Program of China(Nos.2021YFF1200404 and 2021YFA1201200)+2 种基金the National Independent Innovation Demonstration Zone Shanghai Zhangjiang Major Projects(No.ZJZX2020014)the Starry Night Science Fund at Shanghai Institute for Advanced Study of Zhejiang University(No.SN-ZJU-SIAS-003)the Shanghai Artificial Intelligence Lab(No.P22KN00272),China.
文摘Antibodies currently comprise the predominant treatment modality for a variety of diseases;therefore,optimizing their properties rapidly and efficiently is an indispensable step in antibody-based drug development.Inspired by the great success of artificial intelligence-based algorithms,especially deep learning-based methods in the field of biology,various computational methods have been introduced into antibody optimization to reduce costs and increase the success rate of lead candidate generation and optimization.Herein,we briefly review recent progress in deep learning-based antibody optimization,focusing on the available datasets and algorithm input data types that are crucial for constructing appropriate deep learning models.Furthermore,we discuss the current challenges and potential solutions for the future development of general-purpose deep learning algorithms in antibody optimization.
基金The Independent Research Foundation of Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai)under contract No.SML2023SP201the Natural Science Foundation of Guangdong Province,China under contract No.2024A1515012717+3 种基金the Funds of Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai)under contract Nos 313021004 and 313022009the National Natural Science Foundation of China under contract No.41806216the Natural Science Foundation of Jiangsu Province under contract No.BK20211015the Program of Innovation 2030 on Smart Ocean,Zhejiang University.
文摘The oceanic general circulations in the Ross Sea,where the southernmost ocean is located,play an important role in the climate system.Yet,the energy cycle of oceanic circulations in the Ross Sea is still unclear.By employing an eddypermitting coupled regional ocean-sea ice-ice shelf model,this study investigates the oceanic energy cycle in the Ross Sea.Based on the Lorenz Energy Cycle framework,the spatiotemporal distributions of kinetic energy and available potential energy within the Ross Sea are quantitatively analyzed.The power pathways and magnitudes of energy conversion are also quantified.The simulated results show that the Mean Available Potential Energy(MAPE)is the largest energy reservoir of about 527.62 PJ(1 PJ=10^(15) J),followed by the Eddy Available Potential Energy(EAPE),the Mean Kinetic Energy(MKE),and the Eddy Kinetic Energy(EKE)of about 19.20 PJ,1.04 PJ,and 0.82 PJ,respectively.In the sub-ice-shelf cavity,the maximal MAPE is up to about 177.81 PJ,and the EAPE,MKE,and EKE are about 2.58 PJ,39.87 TJ(1 TJ=10^(12) J),and 23.05 TJ,respectively.The inputs to the regional energy reservoirs are mainly from the sea surface momentum and buoyancy fluxes.The baroclinic pathway plays a dominant role in the conversion of energy to EKE,both in the open ocean and in the sub-ice-shelf cavity.The energy conversion from EAPE to EKE in the open ocean and the sub-ice-shelf cavity is about 2.86 GW(1 GW=10^(9) J)and 162.18 MW(1 MW=10^(6) J),respectively.In addition,the kinetic energy is directed from EKE to MKE in the Ross Sea,and such an energy flow in the barotropic pathway is opposite from that in the Southern Ocean.
基金supported by the National Natural Science Foundation of China(No.22064014)the Science and Technology Development Plan Project of Lanzhou(No.2021–1-146)+2 种基金the Science and Technology Project of Gansu Province(Nos.21YF5FA071,21JR7RA538)the Industrial Support Programme for Higher Education Institutions Project(Nos.2023CYZC-69,2024CYCZ-05)the 2023 Gansu Provincial Key Talent Project(No.2023RCXM26)。
文摘The traditional nanozymes-based ratiometric fluorescence sensing platforms usually necessitate the supplementary addition of fluorescent probes,therefore greatly restricting its convenient and broad application.In this study,a highly sensitive and selective ratiometric fluorescence platform for alkaline phosphatase(ALP)detection was established,only employing Prussian blue(PB)nanozymes and a commercially available chromogen of o-phenylenediamine(OPD).PB nanozymes with remarkable peroxidaselike(POD-like)activity can effectively catalyze OPD chromogen to yield 2,3-diaminophenazine(OPDox)with an intense yellow fluorescence at 573 nm emission peak.Target ALP can facilitate ascorbic acid 2-phosphate(AAP)dephosphorylation to generate phosphate and ascorbic acid(AA).Significantly,both these two resultant hydrolysis products could effectively decrease the OPDox generation via a dualpath based inhibition on the PB nanozymes POD-like activity.On the other hand,the generated dehydroascorbic acid(DHAA)from AA oxidation would exclusively react with OPD chromogen to yield3-(dihydroxyethyl)furo[3,4-b]quinoxaline-1-one(DFQ)with a strong blue fluorescent signal at 434nm,which further providing a significant enhancement on the sensing selectivity of ALP detection.As a result,an increased yellow fluorescence of OPDox and decreased blue fluorescence of DFQ could be clearly observed with different ALP addition.A robust linear relationship between the fluorescence ratio of F_(434)/F_(573)and ALP activity ranging from 0.25U/L to 6U/L was obtained,with a low detection limit of 0.112 U/L.This proposed method demonstrates high sensitivity,excellent selectivity,cost-effectiveness,and operational simplicity,yet enabling an effective detection of ALP levels in human serum.
