BACKGROUND Depression,non-suicidal self-injury(NSSI),and suicide attempts(SA)often co-occur during adolescence and are associated with long-term adverse health outcomes.Unfortunately,neural mechanisms underlying self-...BACKGROUND Depression,non-suicidal self-injury(NSSI),and suicide attempts(SA)often co-occur during adolescence and are associated with long-term adverse health outcomes.Unfortunately,neural mechanisms underlying self-injury and SA are poorly understood in depressed adolescents but likely relate to the structural abnormalities in brain regions.AIM To investigate structural network communication within large-scale brain networks in adolescents with depression.METHODS We constructed five distinct network communication models to evaluate structural network efficiency at the whole-brain level in adolescents with depression.Diffusion magnetic resonance imaging data were acquired from 32 healthy controls and 85 depressed adolescents,including 17 depressed adolescents without SA or NSSI(major depressive disorder group),27 depressed adolescents with NSSI but no SA(NSSI group),and 41 depressed adolescents with SA and NSSI(NSSI+SA group).RESULTS Significant differences in structural network communication were observed across the four groups,involving spatially widespread brain regions,particularly encompassing cortico-cortical connections(e.g.,dorsal posterior cingulate gyrus and the right ventral posterior cingulate gyrus;connections based on precentral gyrus)and cortico-subcortical circuits(e.g.,the nucleus accumbens-frontal circuit).In addition,we examined whether compromised communication efficiency was linked to clinical symptoms in the depressed adolescents.We observed significant correlations between network communication efficiencies and clinical scale scores derived from depressed adolescents with NSSI and SA.CONCLUSION This study provides evidence of structural network communication differences in depressed adolescents with NSSI and SA,highlighting impaired neuroanatomical communication efficiency as a potential contributor to their symptoms.These findings offer new insights into the pathophysiological mechanisms underlying the comorbidity of NSSI and SA in adolescent depression.展开更多
Background Globally,suicide is the third leading cause of death among girls aged 15-19 years.However,there is a growing concern that suicide research has paid lttle attention to pregnant adolescent girls,particularly ...Background Globally,suicide is the third leading cause of death among girls aged 15-19 years.However,there is a growing concern that suicide research has paid lttle attention to pregnant adolescent girls,particularly in lowincome and middle-income countries,including Ghana,where nearly one in seven adolescents experiences(unwanted)pregnancy.Aims To assess the prevalence and correlates of suicidal ideation and suicide attempt and the self-reported reasons for attempted suicide among pregnant adolescent girls in Ghana.Methods We collected cross-sectional data(between August 2022 and December 2023)using structured anonymous questionnaires from a sample of 449 pregnant adolescent girls(aged 14-19 years)drawn from the three geographical zones of Ghana.We applied bivariable and multivariable analysis techniques to the data.Results Overall,28.51%(95%confidence interval(Cl)24.37%to 32.93%)reported suicidal ideation,and 18.04%(95%Cl 14.59%to 21.91%)reported suicide attempt during the current pregnancy.Participants who reported attempted suicide endorsed more interpersonal reasons(eg,to communicate distress,to seek help or to influence others)than intrapersonal reasons for their attempted suicide.In the final adjusted logistic regression models,food insecurity(adjusted odds ratio(aOR)=2.69;95%Cl 1.34 to 5.41;p=0.005)was uniquely associated with increased odds of suicidal ideation.Adverse childhood experiences(a0R=3.04;95%CI 1.33 to 6.97;p=0.008),history of attempted suicide before current pregnancy(a0R=3.47;95%CI 1.27 to 9.47;p=0.015)and depression(measured by the 5-item World Health Organization Well-Being Index;aOR=0.31;95%CI 0.12 to 0.77;p=0.012)were uniquely associated with increased odds of suicide attempt.Five variables were commonly associated with increased odds of both suicidal ideation and suicide attempt:conflict with parents,alcohol use,pregnancy-related anxiety,history of attempted suicide and intimate partner violence.While being in junior high school was uniquely associated with reduced odds of suicidal ideation,intimate partner's acceptance of paternity was commonly associated with reduced odds of both suicidal ideation and suicide attempt.Conclusions Although the prevalence estimates of suicidal ideation and suicide attempt in this study are comparable with known rates among non-pregnant adolescent girls in Ghana,additional research is needed to nuance our understanding of the correlates identified in this study.The evidence aiso highlights a need for both routine antepartum primary care mental health screening for suicidality and related risks and targeted prevention and intervention programmes.展开更多
Dear Editor,Major depressive disorder(MDD)is associated with a high rate of suicide attempts(SA).Previous reports have identified risk factors for SA in MDD patients,including sex and metabolic disorders[1].However,to...Dear Editor,Major depressive disorder(MDD)is associated with a high rate of suicide attempts(SA).Previous reports have identified risk factors for SA in MDD patients,including sex and metabolic disorders[1].However,to our knowledge,the impact of sex differences on the association between body mass index(BMI)status and SA in patients with MDD has not been investigated.Th is study aimed to investigate:1)the sex diff erence in the prevalence of recent SA in Chinese drug-naïve fi rst-episode(DNFE)MDD patients,and 2)the eff ect of sex diff erence on the relationship between higher BMI(overweight or obese)and recent SA.Patients were recruited from the First Clinical Medical College of Shanxi Medical University from January 2015 to December 2017.All patients met the inclusion and exclusion criteria described in previous studies[2].展开更多
Internet addiction is associated with an increased risk of suicidal behavior and can lead to brain dysfunction among adolescents.However,whether brain dysfunction occurs in adolescents with Internet addiction who atte...Internet addiction is associated with an increased risk of suicidal behavior and can lead to brain dysfunction among adolescents.However,whether brain dysfunction occurs in adolescents with Internet addiction who attempt suicide remains unknown.This observational cross-sectional study enrolled 41 young Internet addicts,aged from 15 to 20 years,from the Department of Psychiatry,the First Affiliated Hospital of Chongqing Medical University,China from January to May 2018.The participants included 21 individuals who attempted suicide and 20 individuals with Internet addiction without a suicidal attempt history.Brain images in the resting state were obtained by a 3.0 T magnetic resonance imaging scanner.The results showed that activity in the gyrus frontalis inferior of the right pars triangularis and the right pars opercularis was significantly increased in the suicidal attempt group compared with the non-suicidal attempt group.In the resting state,the prefrontal lobe of adolescents who had attempted suicide because of Internet addiction exhibited functional abnormalities,which may provide a new basis for studying suicide pathogenesis in Internet addicts.The study was authorized by the Ethics Committee of Chongqing Medical University,China(approval No.2017 Scientific Research Ethics(2017-157))on December 11,2017.展开更多
Background The association between substance use including marijuana use and attempted suicide has been well documented.However,little is known about marijuana use and its association with attempted suicide repetition...Background The association between substance use including marijuana use and attempted suicide has been well documented.However,little is known about marijuana use and its association with attempted suicide repetition among young people in low-income and middle-income contexts.Aims This analysis was conducted to assess the factors associated with marijuana use and ascertain marijuana use as a determinant of repeated attempted suicide among senior high school(SHS)students in Ghana.Methods Data from the 2012 Global School-Based Student Health Survey in Ghana was used for this study.Modified Poisson,Logistic and Probit models weighted with Mahalanobis distance matching within propensity calliper were employed separately to determine the hypothetical association between marijuana use and repeated attempted suicide.All analysis was performed using Stata 16 and p<0.05 was deemed statistically significant.Results The prevalence estimates of marijuana use and repeated attempted suicide among SHS students in Ghana were 3.4%(95%Cl:2.3 to 5.1)and 11.5%(95%Cl:9.1 to 14.4),respectively.The prevalence of marijuana use was significantly associated with school grade,smoking exposure,parent smoker,alcohol intake and truancy.Marijuana use was positively associated with repeated attempted suicide among SHS in Ghana correlation=0.23,p<0.001.Repeated attempted suicide among students who use marijuana was approximately threefold and fivefold significant compared with nonmarijuana use students,based on the Poisson(adjusted prevalence ratio:3.02;95%Cl:1.67 to 5.43,p<0.001)and Logistic(adjusted OR:5.06;95%Cl:3.19 to 11.64,p<0.001)estimates respectively.Also,the Probit model showed that marijuana use significantly increased the log count of repeated attempted suicide by 95%(ap:0.95;95%CI:0.49 to 1.41,p<0.001).Conclusion Marijuana use does not only influence the onset of suicidal attempts but also repeated attempted suicide among SHS students in Ghana.Special attention is required for suicide attempters with a history of repeated attempts and current marijuana use among SHS students in Ghana.Early identification of the potential risk and protective factors is recommended to inform school-based interventions.National level structured school-based substance abuse interventions and health promotion programmes would be useful.展开更多
Case description:Nurses face more and more ethical dilemmas during their practice nowadays,especially when they are taking care of the patient at end of life stage.The case study demonstrates an ethical dilemma when n...Case description:Nurses face more and more ethical dilemmas during their practice nowadays,especially when they are taking care of the patient at end of life stage.The case study demonstrates an ethical dilemma when nursing staff are taking care of an end stage aggressive prostate cancer patient Mr Green who expressed the suicide thoughts to one of the nurses and ask that nurse keep secret for him in Brisbane,QLD,Australia.Ethical dilemma identification:The ethical dilemma is identified as“if the nursing staff should tell other health care team members about patient's suicide attempt without patient's consent”.Analysis:To better solving this case and making the best moral decision,the ethical theory,the ethical principles and the Australian nurses'code of ethics values statement,the associated literature relative with this case are analyzed before the decision making.Ethical decision making:After consider all of the above factors,in this case,the best ethical decision for the patient is that the nurse share the information of Mr Green's suicide attempt with other health care professionals.Results:In Mr Green's case,the nurse chose to share the information of Mr Green's suicide attempt with other health care professionals.The nursing team followed the self-harm and suicide protocol of the hospital strictly,they maintained the effective communication with Mr Green,identified the factors which cause patient's suicide attempt,provided the appropriate nursing intervention to deal will these risk factors and collaborated with other health care professionals to prefect the further care.The patient transferred to a palliative care service with no sign of suicide attempt and other self-harm behaviors and passed away peacefully 76 days after discharged with his relatives and pastors accompany.展开更多
A case-control study was conducted to investigate associations between organophosphate pesticide（OP）exposure,aggression,impulsivity,and attempted suicide.Questionnaires were used to collect information;impulsivity a...A case-control study was conducted to investigate associations between organophosphate pesticide（OP）exposure,aggression,impulsivity,and attempted suicide.Questionnaires were used to collect information;impulsivity and aggression were measured by the Barratt Impulsivity Scale（BIS）and the Aggression Inventory（AI）.展开更多
Icosahedrons in supercooled liquids and glasses are considered to be of significance for the glass formation in alloy systems. Starting from the similarity of the local structure of quasicrystals to the icosahedrons i...Icosahedrons in supercooled liquids and glasses are considered to be of significance for the glass formation in alloy systems. Starting from the similarity of the local structure of quasicrystals to the icosahedrons in metallic glasses, a scheme is put forward to prepare metallic glasses based on a well-known quasicrystal Zr40Ti40Ni20. A series of （Zr4o Ti40Ni20 ）lOO-x Cos metallic glasses are fabricated, and the optimized glass forming composition is determined at （Zr40 Ti40Ni20 ）92 Cos. The results show that the glass-forming ability of the alloys is c10sely related to the quasicrystalline phases. The mechanism of the enhanced glass-forming ability is discussed.展开更多
Background: The association of eating habits and suicide attempts has been insufficiently studied. Aim: This study aimed to determine the eating habits associated with suicide attempts in a sample of psychiatric outpa...Background: The association of eating habits and suicide attempts has been insufficiently studied. Aim: This study aimed to determine the eating habits associated with suicide attempts in a sample of psychiatric outpatients. Methods: Through a case control study design, 283 psychiatric outpatients attending in two public hospitals in Durango City, Mexico were studied. Of the 283 patients, 156 have had suicide attempts and 127 have not had suicide attempts. Eating habits were obtained from all outpatients and compared in patients with history of suicide attempts and patients without such history. Results: Logistic regression analysis showed differences in eating habits between psychiatric outpatients with and without history of suicide attempts. A history of suicide attempts was positively associated with consumption of pork (OR = 2.35, 95% CI: 1.17 - 4.71;P = 0.01), mutton (OR = 2.38, 95% CI: 1.25 - 4.52;P = 0.008), chorizo (OR = 2.09, 95% CI: 1.04 - 4.19;P = 0.03), unwashed raw vegetables (OR = 3.23, 95% CI: 1.26 - 8.32;P = 0.01), and untreated water (OR = 1.77, 95% CI: 1.03 - 3.02;P = 0.03), and negatively associated with consumption of goat meat (OR = 0.39, 95% CI: 0.17 - 0.90;P = 0.02), and turkey meat (OR = 0.41, 95% CI: 0.23 - 0.73;P = 0.002). Conclusions: This is the first report on the association of eating habits with suicide attempts in psychiatric outpatients. Results suggest that suicide attempts are associated not only with the type of meat consumed but also with poor food hygiene in psychiatric outpatients. Further studies to confirm or challenge such results are needed.展开更多
Background: Confronted to the increasing suicide rate in children, clinicians have to better understand and predict suicide-related behaviours (SRBs) in children with and without depressive symptoms. Aims: To investig...Background: Confronted to the increasing suicide rate in children, clinicians have to better understand and predict suicide-related behaviours (SRBs) in children with and without depressive symptoms. Aims: To investigate associations among suicidal tendencies (thoughts and/or attempts), depression and children’s perceptions of subjective quality of life. Methods: This was a cross-sectional study of 157 children of 6 - 13-year-old. Results: Children who attempted or thought of suicide reported goodless subjective quality of life than nonsuicidal children did, and children who thought of or attempted suicide reported higher levels of depressive symptoms than nonsuicidal children. Limitations: A more rigorous approach to investigating suicidal ideation and depressive symptomatology as a diagnostic interview based on the DSM-IV-TR will be valuable to future progress in understanding children’s suicidality. Conclusions: Results may reflect the confirmation of depressive symptoms as risk factors for suicidality and underline the high importance of social and emotional life context among suicidal children. For this reason, more effective recognition and comprehension of the underlying affective and social conditions of children with suicidality have special importance to prevent future suicidal behaviour during adolescence.展开更多
Genital self-mutilation is an uncommon event that is commonly associated with psychotic disorders. Such injuries have also been reported secondary to complex religious beliefs and delusions regarding sexual guilt. Eve...Genital self-mutilation is an uncommon event that is commonly associated with psychotic disorders. Such injuries have also been reported secondary to complex religious beliefs and delusions regarding sexual guilt. Even though few case reports of male genital self-mutilation are available in literature, it is?rareto have a combined self-genital mutilation and attempted suicide by cut throat occurring in the same patient at presentation. We presented the case of a 38-yr-old male who presented to the accident and emergency centre of a tertiary hospital in Accra, Ghana.展开更多
Objective: This study aims is to conduct a comparative analysis of the clinical and sociodemographic profiles of individuals referred to Consultation-Liaison Psychiatry (CLP) at a tertiary general hospital, specifical...Objective: This study aims is to conduct a comparative analysis of the clinical and sociodemographic profiles of individuals referred to Consultation-Liaison Psychiatry (CLP) at a tertiary general hospital, specifically focusing on those seeking assistance due to suicide attempts (TS) versus CLP requests for other reasons (non-TS) between the years 2010 and 2020. Additionally, we aim to assess factors associated with suicide attempts. Method: This retrospective controlled study involves a thorough examination of medical records encompassing 3913 patients who received CLP services at the Hospital de Base (HB) and the Children and Maternity Hospital (HCM) of São José do Rio Preto Medical School Foundation (Funfarme) from June 2010 to June 2020. The patient cohort is categorized into two groups: those with requests for SA (n = 677) and those with requests for other reasons. Results: In the SA group, as opposed to the non SA group, statistically significant differences were observed for gender (predominantly female), employment status (employed), marital status (single), and age (younger). Notably, a higher prevalence of psychiatric antecedents (88.7%, n = 555 vs. 73.6% n = 2018) was found in the SA group, indicating a significant association. The frequency of SA requests remained stable over the years. Among the SA group, mood disorders were the most prevalent (39%, n = 372), followed by disorders related to substance use (21.2%, n = 202), and personality disorders (16%, n = 152). A history of previous suicide attempts emerged as a crucial factor for the recurrence of SA (p-value ≤ 0.001). Exogenous intoxication emerged as the most frequently employed method in attempts (79.6%, n = 539), particularly prevalent among patients diagnosed with mood disorders (41%, n = 314). A significant association was observed between the method of attempt and the nosological psychiatric diagnosis (χ<sup>2</sup> = 42.277;p ≤ 0.001). Regarding outcomes, the majority of patients were referred for outpatient follow-up (23%, n = 336) in specialized mental health services or at the Primary Healthcare Unit, highlighting the general hospital’s pivotal role in integrating patients into the broader healthcare network. Conclusion: Variables such as gender (female), age group (young adults), and psychiatric history exhibited stronger associations with suicide attempts compared to the group assisted by CLP for other reasons. Furthermore, a noteworthy correlation between the method employed and the psychiatric diagnosis was identified.展开更多
This study aimed to clarify the difference between the not qualified teams and the qualified teams to 2nd stage in the Pass Appearance Time and passes attempted at all group stage games of World Cup 2014 and compared ...This study aimed to clarify the difference between the not qualified teams and the qualified teams to 2nd stage in the Pass Appearance Time and passes attempted at all group stage games of World Cup 2014 and compared with World cup 2010. Results indicated changes in passing in modem football tactics. Actual playing time is represented as Net Playtime in this study. Pass Appearance Time is calculated by Net Playtime divided by passes Attempted. Pass Appearance Time of each team for the all Group stage games was calculated and compared with World cup 2010. No difference was revealed in the 2014 data between teams that did and did not qualify, though the 2010 data revealed differences. World cup 2010 data suggested that increasing passes attempts and lessening Pass Appearance Time were effective in qualifying for the 2rid stage. World cup 2014 data, however, suggested that diversity of tactics was important.展开更多
1 Introduction The Lop Nor playa,located in the eastern end of the Tarim Basin,capped with a thick salt crust covering an area of approximately 5,500 km2(Ma 2007)that closely resembles a"Great Ear"in satelli...1 Introduction The Lop Nor playa,located in the eastern end of the Tarim Basin,capped with a thick salt crust covering an area of approximately 5,500 km2(Ma 2007)that closely resembles a"Great Ear"in satellite images.Understanding the formation of the salt crust can provide important展开更多
An attempt has been made recently to synthesize very neutron-decient 216U isotope in 40Ca+natHf reaction atthe gas-lled recoil separator SHANS[1]. A beam of 40Ca12+ at an energy of Elab=194.6 MeV was delivered by thes...An attempt has been made recently to synthesize very neutron-decient 216U isotope in 40Ca+natHf reaction atthe gas-lled recoil separator SHANS[1]. A beam of 40Ca12+ at an energy of Elab=194.6 MeV was delivered by thesector focusing cyclotron of the Heavy Ion Research Facility in Lanzhou (HIRFL). The average beam intensity wasabout 100 pnA. Self-support targets of natural hafnium foils with thickness of 420 g/cm2 was mounted in a edframe. Evaporation residues recoiled from the target were separated from the primary beam by the separator andthen implanted into the Si-box detector (consist of three position sensitive silicon detectors and eight non-positionsensitive silicon detectors)[2]. In order to distinguish the -decay events from the implantation events, two multi-wire proportional counters (MWPCs) were mounted upstream from the Si-box detector. Behind the Si-box detectora fourfold segmented Clover detector was installed for -ray studies.展开更多
Proposed by the Chinese Government,China and 16 Central and East European(CEE)countries jointly launched the framework of 16+1 cooperation in 2012.China has actively practiced the concept of openness,inclusiveness and...Proposed by the Chinese Government,China and 16 Central and East European(CEE)countries jointly launched the framework of 16+1 cooperation in 2012.China has actively practiced the concept of openness,inclusiveness and win-win cooperation,putting it into the framework of 16+1 cooperation and making new attempts in constructing a new model of international relations.Over the展开更多
In 1984, under the guideline laid down by the Communist Party of China, "economic construction must rely on science and technology, and science and technology must be geared to serve economic construction", ...In 1984, under the guideline laid down by the Communist Party of China, "economic construction must rely on science and technology, and science and technology must be geared to serve economic construction", the CAS began to encourage enthusiastically its scientific and technical personnel to run high-and new tech enterprises.At present,there are more than 500 S&T enterprises at the Academy,including five (group)corporations directly under the jurisdiction of the Academy, 21 co-operation enterprises,40 or so展开更多
基金Supported by the National Natural Science Foundation of China,No.81871081 and No.62201265the Fundamental Research Funds for the Central Universities,No.NJ2024029-14the Talent Support Programs of Wuxi Health Commission,No.BJ2023085,No.FZXK2021012,and No.M202358.
文摘BACKGROUND Depression,non-suicidal self-injury(NSSI),and suicide attempts(SA)often co-occur during adolescence and are associated with long-term adverse health outcomes.Unfortunately,neural mechanisms underlying self-injury and SA are poorly understood in depressed adolescents but likely relate to the structural abnormalities in brain regions.AIM To investigate structural network communication within large-scale brain networks in adolescents with depression.METHODS We constructed five distinct network communication models to evaluate structural network efficiency at the whole-brain level in adolescents with depression.Diffusion magnetic resonance imaging data were acquired from 32 healthy controls and 85 depressed adolescents,including 17 depressed adolescents without SA or NSSI(major depressive disorder group),27 depressed adolescents with NSSI but no SA(NSSI group),and 41 depressed adolescents with SA and NSSI(NSSI+SA group).RESULTS Significant differences in structural network communication were observed across the four groups,involving spatially widespread brain regions,particularly encompassing cortico-cortical connections(e.g.,dorsal posterior cingulate gyrus and the right ventral posterior cingulate gyrus;connections based on precentral gyrus)and cortico-subcortical circuits(e.g.,the nucleus accumbens-frontal circuit).In addition,we examined whether compromised communication efficiency was linked to clinical symptoms in the depressed adolescents.We observed significant correlations between network communication efficiencies and clinical scale scores derived from depressed adolescents with NSSI and SA.CONCLUSION This study provides evidence of structural network communication differences in depressed adolescents with NSSI and SA,highlighting impaired neuroanatomical communication efficiency as a potential contributor to their symptoms.These findings offer new insights into the pathophysiological mechanisms underlying the comorbidity of NSSI and SA in adolescent depression.
基金the Global WACh Rising Star Seed Award by the Department of Global Health,University of Washington,Seattle,USA(Grant No:UW/GWACh/RSA/2023-01)。
文摘Background Globally,suicide is the third leading cause of death among girls aged 15-19 years.However,there is a growing concern that suicide research has paid lttle attention to pregnant adolescent girls,particularly in lowincome and middle-income countries,including Ghana,where nearly one in seven adolescents experiences(unwanted)pregnancy.Aims To assess the prevalence and correlates of suicidal ideation and suicide attempt and the self-reported reasons for attempted suicide among pregnant adolescent girls in Ghana.Methods We collected cross-sectional data(between August 2022 and December 2023)using structured anonymous questionnaires from a sample of 449 pregnant adolescent girls(aged 14-19 years)drawn from the three geographical zones of Ghana.We applied bivariable and multivariable analysis techniques to the data.Results Overall,28.51%(95%confidence interval(Cl)24.37%to 32.93%)reported suicidal ideation,and 18.04%(95%Cl 14.59%to 21.91%)reported suicide attempt during the current pregnancy.Participants who reported attempted suicide endorsed more interpersonal reasons(eg,to communicate distress,to seek help or to influence others)than intrapersonal reasons for their attempted suicide.In the final adjusted logistic regression models,food insecurity(adjusted odds ratio(aOR)=2.69;95%Cl 1.34 to 5.41;p=0.005)was uniquely associated with increased odds of suicidal ideation.Adverse childhood experiences(a0R=3.04;95%CI 1.33 to 6.97;p=0.008),history of attempted suicide before current pregnancy(a0R=3.47;95%CI 1.27 to 9.47;p=0.015)and depression(measured by the 5-item World Health Organization Well-Being Index;aOR=0.31;95%CI 0.12 to 0.77;p=0.012)were uniquely associated with increased odds of suicide attempt.Five variables were commonly associated with increased odds of both suicidal ideation and suicide attempt:conflict with parents,alcohol use,pregnancy-related anxiety,history of attempted suicide and intimate partner violence.While being in junior high school was uniquely associated with reduced odds of suicidal ideation,intimate partner's acceptance of paternity was commonly associated with reduced odds of both suicidal ideation and suicide attempt.Conclusions Although the prevalence estimates of suicidal ideation and suicide attempt in this study are comparable with known rates among non-pregnant adolescent girls in Ghana,additional research is needed to nuance our understanding of the correlates identified in this study.The evidence aiso highlights a need for both routine antepartum primary care mental health screening for suicidality and related risks and targeted prevention and intervention programmes.
基金supported by the Guangzhou Municiple Health Commission(2023 C-TS26)the Opening Foundation of Jiangsu Key Laboratory of Neurodegeneration,Nanjing Medical University(KF202202)+1 种基金the Plan on Enhancing Scientific Research in Guangzhou Medical University(02-410-230221XM,GMUCR2024-02025)the Project of Guangzhou Municipal Science and Technology Bureau(2023A03J0835).
文摘Dear Editor,Major depressive disorder(MDD)is associated with a high rate of suicide attempts(SA).Previous reports have identified risk factors for SA in MDD patients,including sex and metabolic disorders[1].However,to our knowledge,the impact of sex differences on the association between body mass index(BMI)status and SA in patients with MDD has not been investigated.Th is study aimed to investigate:1)the sex diff erence in the prevalence of recent SA in Chinese drug-naïve fi rst-episode(DNFE)MDD patients,and 2)the eff ect of sex diff erence on the relationship between higher BMI(overweight or obese)and recent SA.Patients were recruited from the First Clinical Medical College of Shanxi Medical University from January 2015 to December 2017.All patients met the inclusion and exclusion criteria described in previous studies[2].
基金supported by a grant from Chongqing Science and Technology Commission of China,Nos.CSTC2018jxj1130009,cstc2019 jscx-msxmX0279(both to YH)the Traditional Chinese Medicine Scientific Research Fund from Chongqing Health Committee of China,No.2019ZY023315(to YH)
文摘Internet addiction is associated with an increased risk of suicidal behavior and can lead to brain dysfunction among adolescents.However,whether brain dysfunction occurs in adolescents with Internet addiction who attempt suicide remains unknown.This observational cross-sectional study enrolled 41 young Internet addicts,aged from 15 to 20 years,from the Department of Psychiatry,the First Affiliated Hospital of Chongqing Medical University,China from January to May 2018.The participants included 21 individuals who attempted suicide and 20 individuals with Internet addiction without a suicidal attempt history.Brain images in the resting state were obtained by a 3.0 T magnetic resonance imaging scanner.The results showed that activity in the gyrus frontalis inferior of the right pars triangularis and the right pars opercularis was significantly increased in the suicidal attempt group compared with the non-suicidal attempt group.In the resting state,the prefrontal lobe of adolescents who had attempted suicide because of Internet addiction exhibited functional abnormalities,which may provide a new basis for studying suicide pathogenesis in Internet addicts.The study was authorized by the Ethics Committee of Chongqing Medical University,China(approval No.2017 Scientific Research Ethics(2017-157))on December 11,2017.
文摘Background The association between substance use including marijuana use and attempted suicide has been well documented.However,little is known about marijuana use and its association with attempted suicide repetition among young people in low-income and middle-income contexts.Aims This analysis was conducted to assess the factors associated with marijuana use and ascertain marijuana use as a determinant of repeated attempted suicide among senior high school(SHS)students in Ghana.Methods Data from the 2012 Global School-Based Student Health Survey in Ghana was used for this study.Modified Poisson,Logistic and Probit models weighted with Mahalanobis distance matching within propensity calliper were employed separately to determine the hypothetical association between marijuana use and repeated attempted suicide.All analysis was performed using Stata 16 and p<0.05 was deemed statistically significant.Results The prevalence estimates of marijuana use and repeated attempted suicide among SHS students in Ghana were 3.4%(95%Cl:2.3 to 5.1)and 11.5%(95%Cl:9.1 to 14.4),respectively.The prevalence of marijuana use was significantly associated with school grade,smoking exposure,parent smoker,alcohol intake and truancy.Marijuana use was positively associated with repeated attempted suicide among SHS in Ghana correlation=0.23,p<0.001.Repeated attempted suicide among students who use marijuana was approximately threefold and fivefold significant compared with nonmarijuana use students,based on the Poisson(adjusted prevalence ratio:3.02;95%Cl:1.67 to 5.43,p<0.001)and Logistic(adjusted OR:5.06;95%Cl:3.19 to 11.64,p<0.001)estimates respectively.Also,the Probit model showed that marijuana use significantly increased the log count of repeated attempted suicide by 95%(ap:0.95;95%CI:0.49 to 1.41,p<0.001).Conclusion Marijuana use does not only influence the onset of suicidal attempts but also repeated attempted suicide among SHS students in Ghana.Special attention is required for suicide attempters with a history of repeated attempts and current marijuana use among SHS students in Ghana.Early identification of the potential risk and protective factors is recommended to inform school-based interventions.National level structured school-based substance abuse interventions and health promotion programmes would be useful.
文摘Case description:Nurses face more and more ethical dilemmas during their practice nowadays,especially when they are taking care of the patient at end of life stage.The case study demonstrates an ethical dilemma when nursing staff are taking care of an end stage aggressive prostate cancer patient Mr Green who expressed the suicide thoughts to one of the nurses and ask that nurse keep secret for him in Brisbane,QLD,Australia.Ethical dilemma identification:The ethical dilemma is identified as“if the nursing staff should tell other health care team members about patient's suicide attempt without patient's consent”.Analysis:To better solving this case and making the best moral decision,the ethical theory,the ethical principles and the Australian nurses'code of ethics values statement,the associated literature relative with this case are analyzed before the decision making.Ethical decision making:After consider all of the above factors,in this case,the best ethical decision for the patient is that the nurse share the information of Mr Green's suicide attempt with other health care professionals.Results:In Mr Green's case,the nurse chose to share the information of Mr Green's suicide attempt with other health care professionals.The nursing team followed the self-harm and suicide protocol of the hospital strictly,they maintained the effective communication with Mr Green,identified the factors which cause patient's suicide attempt,provided the appropriate nursing intervention to deal will these risk factors and collaborated with other health care professionals to prefect the further care.The patient transferred to a palliative care service with no sign of suicide attempt and other self-harm behaviors and passed away peacefully 76 days after discharged with his relatives and pastors accompany.
基金partially supported by the Colorado Injury Control Research Center Grant Number 5R49CE001168 from the Centers for Disease Control and Preventionthe USA-China Agricultural Injury Research Training Project Grant Number 5DW43TW007257 from the National Institutes of Health,Fogarty International Center
文摘A case-control study was conducted to investigate associations between organophosphate pesticide（OP）exposure,aggression,impulsivity,and attempted suicide.Questionnaires were used to collect information;impulsivity and aggression were measured by the Barratt Impulsivity Scale（BIS）and the Aggression Inventory（AI）.
基金Supported by the National Basic Research Program of China under Grant No 2010CB731604the National Natural Science Foundation of China under Grant Nos 51131002,51071138 and 51271160the Program of Qinhuangdao Science and Technology Bureau under Grant No 201401A051
文摘Icosahedrons in supercooled liquids and glasses are considered to be of significance for the glass formation in alloy systems. Starting from the similarity of the local structure of quasicrystals to the icosahedrons in metallic glasses, a scheme is put forward to prepare metallic glasses based on a well-known quasicrystal Zr40Ti40Ni20. A series of （Zr4o Ti40Ni20 ）lOO-x Cos metallic glasses are fabricated, and the optimized glass forming composition is determined at （Zr40 Ti40Ni20 ）92 Cos. The results show that the glass-forming ability of the alloys is c10sely related to the quasicrystalline phases. The mechanism of the enhanced glass-forming ability is discussed.
文摘Background: The association of eating habits and suicide attempts has been insufficiently studied. Aim: This study aimed to determine the eating habits associated with suicide attempts in a sample of psychiatric outpatients. Methods: Through a case control study design, 283 psychiatric outpatients attending in two public hospitals in Durango City, Mexico were studied. Of the 283 patients, 156 have had suicide attempts and 127 have not had suicide attempts. Eating habits were obtained from all outpatients and compared in patients with history of suicide attempts and patients without such history. Results: Logistic regression analysis showed differences in eating habits between psychiatric outpatients with and without history of suicide attempts. A history of suicide attempts was positively associated with consumption of pork (OR = 2.35, 95% CI: 1.17 - 4.71;P = 0.01), mutton (OR = 2.38, 95% CI: 1.25 - 4.52;P = 0.008), chorizo (OR = 2.09, 95% CI: 1.04 - 4.19;P = 0.03), unwashed raw vegetables (OR = 3.23, 95% CI: 1.26 - 8.32;P = 0.01), and untreated water (OR = 1.77, 95% CI: 1.03 - 3.02;P = 0.03), and negatively associated with consumption of goat meat (OR = 0.39, 95% CI: 0.17 - 0.90;P = 0.02), and turkey meat (OR = 0.41, 95% CI: 0.23 - 0.73;P = 0.002). Conclusions: This is the first report on the association of eating habits with suicide attempts in psychiatric outpatients. Results suggest that suicide attempts are associated not only with the type of meat consumed but also with poor food hygiene in psychiatric outpatients. Further studies to confirm or challenge such results are needed.
文摘Background: Confronted to the increasing suicide rate in children, clinicians have to better understand and predict suicide-related behaviours (SRBs) in children with and without depressive symptoms. Aims: To investigate associations among suicidal tendencies (thoughts and/or attempts), depression and children’s perceptions of subjective quality of life. Methods: This was a cross-sectional study of 157 children of 6 - 13-year-old. Results: Children who attempted or thought of suicide reported goodless subjective quality of life than nonsuicidal children did, and children who thought of or attempted suicide reported higher levels of depressive symptoms than nonsuicidal children. Limitations: A more rigorous approach to investigating suicidal ideation and depressive symptomatology as a diagnostic interview based on the DSM-IV-TR will be valuable to future progress in understanding children’s suicidality. Conclusions: Results may reflect the confirmation of depressive symptoms as risk factors for suicidality and underline the high importance of social and emotional life context among suicidal children. For this reason, more effective recognition and comprehension of the underlying affective and social conditions of children with suicidality have special importance to prevent future suicidal behaviour during adolescence.
文摘Genital self-mutilation is an uncommon event that is commonly associated with psychotic disorders. Such injuries have also been reported secondary to complex religious beliefs and delusions regarding sexual guilt. Even though few case reports of male genital self-mutilation are available in literature, it is?rareto have a combined self-genital mutilation and attempted suicide by cut throat occurring in the same patient at presentation. We presented the case of a 38-yr-old male who presented to the accident and emergency centre of a tertiary hospital in Accra, Ghana.
文摘Objective: This study aims is to conduct a comparative analysis of the clinical and sociodemographic profiles of individuals referred to Consultation-Liaison Psychiatry (CLP) at a tertiary general hospital, specifically focusing on those seeking assistance due to suicide attempts (TS) versus CLP requests for other reasons (non-TS) between the years 2010 and 2020. Additionally, we aim to assess factors associated with suicide attempts. Method: This retrospective controlled study involves a thorough examination of medical records encompassing 3913 patients who received CLP services at the Hospital de Base (HB) and the Children and Maternity Hospital (HCM) of São José do Rio Preto Medical School Foundation (Funfarme) from June 2010 to June 2020. The patient cohort is categorized into two groups: those with requests for SA (n = 677) and those with requests for other reasons. Results: In the SA group, as opposed to the non SA group, statistically significant differences were observed for gender (predominantly female), employment status (employed), marital status (single), and age (younger). Notably, a higher prevalence of psychiatric antecedents (88.7%, n = 555 vs. 73.6% n = 2018) was found in the SA group, indicating a significant association. The frequency of SA requests remained stable over the years. Among the SA group, mood disorders were the most prevalent (39%, n = 372), followed by disorders related to substance use (21.2%, n = 202), and personality disorders (16%, n = 152). A history of previous suicide attempts emerged as a crucial factor for the recurrence of SA (p-value ≤ 0.001). Exogenous intoxication emerged as the most frequently employed method in attempts (79.6%, n = 539), particularly prevalent among patients diagnosed with mood disorders (41%, n = 314). A significant association was observed between the method of attempt and the nosological psychiatric diagnosis (χ<sup>2</sup> = 42.277;p ≤ 0.001). Regarding outcomes, the majority of patients were referred for outpatient follow-up (23%, n = 336) in specialized mental health services or at the Primary Healthcare Unit, highlighting the general hospital’s pivotal role in integrating patients into the broader healthcare network. Conclusion: Variables such as gender (female), age group (young adults), and psychiatric history exhibited stronger associations with suicide attempts compared to the group assisted by CLP for other reasons. Furthermore, a noteworthy correlation between the method employed and the psychiatric diagnosis was identified.
文摘This study aimed to clarify the difference between the not qualified teams and the qualified teams to 2nd stage in the Pass Appearance Time and passes attempted at all group stage games of World Cup 2014 and compared with World cup 2010. Results indicated changes in passing in modem football tactics. Actual playing time is represented as Net Playtime in this study. Pass Appearance Time is calculated by Net Playtime divided by passes Attempted. Pass Appearance Time of each team for the all Group stage games was calculated and compared with World cup 2010. No difference was revealed in the 2014 data between teams that did and did not qualify, though the 2010 data revealed differences. World cup 2010 data suggested that increasing passes attempts and lessening Pass Appearance Time were effective in qualifying for the 2rid stage. World cup 2014 data, however, suggested that diversity of tactics was important.
基金supported by National Natural Science Foundation of China (Grant No. 41002028)Central Public-interest Scientific Institution Basal Research Fund (Grant No. K1102)
文摘1 Introduction The Lop Nor playa,located in the eastern end of the Tarim Basin,capped with a thick salt crust covering an area of approximately 5,500 km2(Ma 2007)that closely resembles a"Great Ear"in satellite images.Understanding the formation of the salt crust can provide important
文摘An attempt has been made recently to synthesize very neutron-decient 216U isotope in 40Ca+natHf reaction atthe gas-lled recoil separator SHANS[1]. A beam of 40Ca12+ at an energy of Elab=194.6 MeV was delivered by thesector focusing cyclotron of the Heavy Ion Research Facility in Lanzhou (HIRFL). The average beam intensity wasabout 100 pnA. Self-support targets of natural hafnium foils with thickness of 420 g/cm2 was mounted in a edframe. Evaporation residues recoiled from the target were separated from the primary beam by the separator andthen implanted into the Si-box detector (consist of three position sensitive silicon detectors and eight non-positionsensitive silicon detectors)[2]. In order to distinguish the -decay events from the implantation events, two multi-wire proportional counters (MWPCs) were mounted upstream from the Si-box detector. Behind the Si-box detectora fourfold segmented Clover detector was installed for -ray studies.
文摘Proposed by the Chinese Government,China and 16 Central and East European(CEE)countries jointly launched the framework of 16+1 cooperation in 2012.China has actively practiced the concept of openness,inclusiveness and win-win cooperation,putting it into the framework of 16+1 cooperation and making new attempts in constructing a new model of international relations.Over the
文摘In 1984, under the guideline laid down by the Communist Party of China, "economic construction must rely on science and technology, and science and technology must be geared to serve economic construction", the CAS began to encourage enthusiastically its scientific and technical personnel to run high-and new tech enterprises.At present,there are more than 500 S&T enterprises at the Academy,including five (group)corporations directly under the jurisdiction of the Academy, 21 co-operation enterprises,40 or so
