Near-Earth objects are important not only in studying the early formation of the Solar System,but also because they pose a serious hazard to humanity when they make close approaches to the Earth.Study of their physica...Near-Earth objects are important not only in studying the early formation of the Solar System,but also because they pose a serious hazard to humanity when they make close approaches to the Earth.Study of their physical properties can provide useful information on their origin,evolution,and hazard to human beings.However,it remains challenging to investigate small,newly discovered,near-Earth objects because of our limited observational window.This investigation seeks to determine the visible colors of near-Earth asteroids(NEAs),perform an initial taxonomic classification based on visible colors and analyze possible correlations between the distribution of taxonomic classification and asteroid size or orbital parameters.Observations were performed in the broadband BVRI Johnson−Cousins photometric system,applied to images from the Yaoan High Precision Telescope and the 1.88 m telescope at the Kottamia Astronomical Observatory.We present new photometric observations of 84 near-Earth asteroids,and classify 80 of them taxonomically,based on their photometric colors.We find that nearly half(46.3%)of the objects in our sample can be classified as S-complex,26.3%as C-complex,6%as D-complex,and 15.0%as X-complex;the remaining belong to the A-or V-types.Additionally,we identify three P-type NEAs in our sample,according to the Tholen scheme.The fractional abundances of the C/X-complex members with absolute magnitude H≥17.0 were more than twice as large as those with H<17.0.However,the fractions of C-and S-complex members with diameters≤1 km and>1 km are nearly equal,while X-complex members tend to have sub-kilometer diameters.In our sample,the C/D-complex objects are predominant among those with a Jovian Tisserand parameter of T_(J)<3.1.These bodies could have a cometary origin.C-and S-complex members account for a considerable proportion of the asteroids that are potentially hazardous.展开更多
The SiTian project,with its vast field of view,will become an ideal platform for scientific research on asteroids.In this study,we develop a pipeline to analyze the photometry of asteroids and derive their periods fro...The SiTian project,with its vast field of view,will become an ideal platform for scientific research on asteroids.In this study,we develop a pipeline to analyze the photometry of asteroids and derive their periods from the data collected by the SiTian pathfinder project Mini-SiTian(MST).The pipeline is applied to the MST f02 region,an MST test region with a sky area of 2°.29×1°.53.Rotation periods of 22 asteroids are derived by the obtained light curve analysis.Among them,there are eight asteroids available in the Asteroid Lightcurve Photometry Database(ALCDEF),and six of them with more photometric points(>200)that have similar period parameters as the ones in ALCDEF.Additionally,the periods for 14 of these asteroids are newly obtained and are not listed in ALCDEF.This study demonstrates the feasibility of asteroid photometric research by the SiTian project.It shows that future observations from the SiTian project will provide even more photometry of asteroids,significantly increasing the number of available light curves.The potential vast photometric data on asteroids will help us to further understand the physics of asteroids,their material composition,and the formation and evolution of the solar system.展开更多
BACKGROUND Currently,very few studies have examined the analgesic effectiveness and safety of dexmedetomidine-assisted intravenous-inhalation combined general anesthesia in laparoscopic minimally invasive surgery for ...BACKGROUND Currently,very few studies have examined the analgesic effectiveness and safety of dexmedetomidine-assisted intravenous-inhalation combined general anesthesia in laparoscopic minimally invasive surgery for inguinal hernia.AIM To investigate the analgesic effect and safety of dexmedetomidine-assisted intravenous-inhalation combined general anesthesia in laparoscopic minimally invasive surgery for inguinal hernia.METHODS In this retrospective study,94 patients scheduled for laparoscopic minimally invasive surgery for inguinal hernia,admitted to Yiwu Central Hospital between May 2022 and May 2023,were divided into a control group(inhalation combined general anesthesia)and a treatment group(dexmedetomidine-assisted intrave-nous-inhalation combined general anesthesia).Perioperative indicators,analgesic effect,preoperative and postoperative 24-hours blood pressure(BP)and heart rate(HR),stress indicators,immune function levels,and adverse reactions were com-pared between the two groups.RESULTS Baseline data,including age,hernia location,place of residence,weight,monthly income,education level,and underlying diseases,were not significantly different between the two groups,indicating comparability(P>0.05).No significant difference was found in operation time and anesthesia time between the two groups(P>0.05).However,the treatment group exhibited a shorter postoperative urinary catheter removal time and hospital stay than the control group(P<0.05).Preoperatively,no significant differences were found in the visual analog scale(VAS)scores between the two groups(P>0.05).However,at 12,18,and 24 hours postoper-atively,the treatment group had significantly lower VAS scores than the control group(P<0.05).Although no significant differences in preoperative hemodynamic indicators were found between the two groups(P>0.05),both groups experienced some extent of changes in postoperative HR,diastolic BP(DBP),and systolic BP(SBP).Nevertheless,the treatment group showed smaller changes in HR,DBP,and SBP than the control group(P<0.05).Preoperative immune function indicators showed no significant differences between the two groups(P>0.05).However,postoperatively,the treatment group demonstrated higher levels of CD3+,CD4+,and CD4+/CD8+and lower levels of CD8+than the control group(P<0.05).The rates of adverse reactions were 6.38%and 23.40%in the treatment and control groups,respectively,revealing a significant difference(χ2=5.371,P=0.020).CONCLUSION Dexmedetomidine-assisted intravenous-inhalation combined general anesthesia can promote early recovery of patients undergoing laparoscopic minimally invasive surgery for inguinal hernia.It ensures stable blood flow,improves postoperative analgesic effects,reduces postoperative pain intensity,alleviates stress response,improves immune function,facilitates anesthesia recovery,and enhances safety.展开更多
Face liveness detection is essential for securing biometric authentication systems against spoofing attacks,including printed photos,replay videos,and 3D masks.This study systematically evaluates pre-trained CNN model...Face liveness detection is essential for securing biometric authentication systems against spoofing attacks,including printed photos,replay videos,and 3D masks.This study systematically evaluates pre-trained CNN models—DenseNet201,VGG16,InceptionV3,ResNet50,VGG19,MobileNetV2,Xception,and InceptionResNetV2—leveraging transfer learning and fine-tuning to enhance liveness detection performance.The models were trained and tested on NUAA and Replay-Attack datasets,with cross-dataset generalization validated on SiW-MV2 to assess real-world adaptability.Performance was evaluated using accuracy,precision,recall,FAR,FRR,HTER,and specialized spoof detection metrics(APCER,NPCER,ACER).Fine-tuning significantly improved detection accuracy,with DenseNet201 achieving the highest performance(98.5%on NUAA,97.71%on Replay-Attack),while MobileNetV2 proved the most efficient model for real-time applications(latency:15 ms,memory usage:45 MB,energy consumption:30 mJ).A statistical significance analysis(paired t-tests,confidence intervals)validated these improvements.Cross-dataset experiments identified DenseNet201 and MobileNetV2 as the most generalizable architectures,with DenseNet201 achieving 86.4%accuracy on Replay-Attack when trained on NUAA,demonstrating robust feature extraction and adaptability.In contrast,ResNet50 showed lower generalization capabilities,struggling with dataset variability and complex spoofing attacks.These findings suggest that MobileNetV2 is well-suited for low-power applications,while DenseNet201 is ideal for high-security environments requiring superior accuracy.This research provides a framework for improving real-time face liveness detection,enhancing biometric security,and guiding future advancements in AI-driven anti-spoofing techniques.展开更多
Retinal blood vessel segmentation is crucial for diagnosing ocular and cardiovascular diseases.Although the introduction of U-Net in 2015 by Olaf Ronneberger significantly advanced this field,yet issues like limited t...Retinal blood vessel segmentation is crucial for diagnosing ocular and cardiovascular diseases.Although the introduction of U-Net in 2015 by Olaf Ronneberger significantly advanced this field,yet issues like limited training data,imbalance data distribution,and inadequate feature extraction persist,hindering both the segmentation performance and optimal model generalization.Addressing these critical issues,the DEFFA-Unet is proposed featuring an additional encoder to process domain-invariant pre-processed inputs,thereby improving both richer feature encoding and enhanced model generalization.A feature filtering fusion module is developed to ensure the precise feature filtering and robust hybrid feature fusion.In response to the task-specific need for higher precision where false positives are very costly,traditional skip connections are replaced with the attention-guided feature reconstructing fusion module.Additionally,innovative data augmentation and balancing methods are proposed to counter data scarcity and distribution imbalance,further boosting the robustness and generalization of the model.With a comprehensive suite of evaluation metrics,extensive validations on four benchmark datasets(DRIVE,CHASEDB1,STARE,and HRF)and an SLO dataset(IOSTAR),demonstrate the proposed method’s superiority over both baseline and state-of-the-art models.Particularly the proposed method significantly outperforms the compared methods in cross-validation model generalization.展开更多
Flexible lander,composed of multiple nodes connected by flexible material,can reducethe bouncing and overturning during the asteroid landing.To satisfy the complex constraints inthe node cooperation of the flexible la...Flexible lander,composed of multiple nodes connected by flexible material,can reducethe bouncing and overturning during the asteroid landing.To satisfy the complex constraints inthe node cooperation of the flexible landing,an intelligent cooperative guidance method is pro-posed.The method consists of a double-layer cooperative guidance structure,a guidance parameterdetermination approach,and an action priority strategy.The double-layer contains a basic guid-ance used to satisfy the terminal state constraints,and a compensatory guidance used to satisfythe lander's attitude constraint.For the compensatory guidance,the parameters are determinedby multi-agent system,which are trained according to the performance index of flexible landing tra-jectories.The action priority strategy is used to reduce the detrimental effect of parameter inconsis-tency on the node cooperation.The simulation of flexible landing shows that the cooperativeguidance method is effective in improving the landing accuracy while satisfying the constraints.Meanwhile,the method is robust to the disturbance in the navigation and control.展开更多
The US 2024 general election ended with the Republican Party winning the presidential, House and Senate elections at the same time. In the presidential election, the Republican Party not only won more popular votes in...The US 2024 general election ended with the Republican Party winning the presidential, House and Senate elections at the same time. In the presidential election, the Republican Party not only won more popular votes in over 90% counties than in the 2020 general election, but also won seven highly contested swing States with greater edges. This also marks the first time since 2004 that the Republican Party has won a relative majority of popular votes in the presidential election.展开更多
Implementing the flyby to Near-Earth Asteroids (NEAs) with the potential impact risks to the Earth allows for obtaining detailed physical parameters, thereby supporting the high-precision orbit prediction and planetar...Implementing the flyby to Near-Earth Asteroids (NEAs) with the potential impact risks to the Earth allows for obtaining detailed physical parameters, thereby supporting the high-precision orbit prediction and planetary defense strategy. Different from those conducted asteroid flyby missions, in the 12th China Trajectory Optimization Competition (CTOC-12), a NEAs flyby trajectory design problem using reusable probes that depart from a Lunar Distant Retrograde Orbit (DRO) station in the cislunar space was released. The objective was flyby to as many NEAs as possible using up to 20 probes within a total of 10 years. The ∑ team proposed a solution that can explore 47 NEAs using 11 probes, ranking the first in the competition. In this paper, the methods and results from the winning team are introduced, including mission analysis and preliminary design, and low-energy transfer trajectory optimization. In particular, a round-trip trajectory is divided into three phases: deep space transfer, indirect transfer between the Earth to DRO, and DRO phasing and rendezvous. With the combination of global optimization and local optimization algorithms, the required velocity increments to change the orbital planes are effectively reduced, thus increasing the number of the explored NEAs. The final solution of our team is presented and the results are compared with those of the top three teams. The competition demonstrates that the regularization of flyby missions from the cislunar space to explore NEAs with the potential impact risks to the Earth is the feasible and promising.展开更多
Strengthening cybersecurity education for college students holds significant importance in achieving the strategic goal of building China into a cyber power.This article begins by discussing the significance and neces...Strengthening cybersecurity education for college students holds significant importance in achieving the strategic goal of building China into a cyber power.This article begins by discussing the significance and necessity of implementing cybersecurity education for university students.Drawing on disciplinary characteristics and student learning analysis,it presents a comprehensive construction process and countermeasures for a general cybersecurity education course,covering aspects such as teaching content development,teaching resource creation,and pedagogical approaches.The aim is to provide reference and guidance for other universities in developing general cybersecurity education courses.展开更多
Digital twin shows broad application prospects in the aerospace field.This paper introduces a generalized satellite digital twin system in detail.With the innovative design concepts of modularization,generalization an...Digital twin shows broad application prospects in the aerospace field.This paper introduces a generalized satellite digital twin system in detail.With the innovative design concepts of modularization,generalization and modeling,on the one hand,the system has successfully achieved the reuse of software modules among different satellite models;on the other hand,it has achieved the reuse of software modules between the digital twin and the testing system,significantly improving the development efficiency of the digital twin system.The paper elaborates on the technical architecture and application fields of this digital twin system,and further prospects its future development.At the same time,through a real inorbit case,the engineering value of the digital twin system is strongly demonstrated.展开更多
The phenomenon of fear memory generalization can be defined as the expansion of an individual's originally specific fear responses to a similar yet genuinely harmless stimulus or situation subsequent to the occurr...The phenomenon of fear memory generalization can be defined as the expansion of an individual's originally specific fear responses to a similar yet genuinely harmless stimulus or situation subsequent to the occurrence of a traumatic event[1].Fear generalization within the normal range represents an adaptive evolutionary mechanism to facilitate prompt reactions to potential threats and to enhance the likelihood of survival.展开更多
The challenge of enhancing the generalization capacity of reinforcement learning(RL)agents remains a formidable obstacle.Existing RL methods,despite achieving superhuman performance on certain benchmarks,often struggl...The challenge of enhancing the generalization capacity of reinforcement learning(RL)agents remains a formidable obstacle.Existing RL methods,despite achieving superhuman performance on certain benchmarks,often struggle with this aspect.A potential reason is that the benchmarks used for training and evaluation may not adequately offer a diverse set of transferable tasks.Although recent studies have developed bench-marking environments to address this shortcoming,they typically fall short in providing tasks that both ensure a solid foundation for generalization and exhibit significant variability.To overcome these limitations,this work introduces the concept that‘objects are composed of more fundamental components’in environment design,as implemented in the proposed environment called summon the magic(StM).This environment generates tasks where objects are derived from extensible and shareable basic components,facilitating strategy reuse and enhancing generalization.Furthermore,two new metrics,adaptation sensitivity range(ASR)and parameter correlation coefficient(PCC),are proposed to better capture and evaluate the generalization process of RL agents.Experimental results show that increasing the number of basic components of the object reduces the proximal policy optimization(PPO)agent’s training-testing gap by 60.9%(in episode reward),significantly alleviating overfitting.Additionally,linear variations in other environmental factors,such as the training monster set proportion and the total number of basic components,uniformly decrease the gap by at least 32.1%.These results highlight StM’s effectiveness in benchmarking and probing the generalization capabilities of RL algorithms.展开更多
Mingalarpar!On behalf of the Consulate-General of the Republic of the Union of Myanmar in Nanning,I would like to express my sincerest congratulations to CAEXPO on reaching the remarkable milestone of over 20 years—a...Mingalarpar!On behalf of the Consulate-General of the Republic of the Union of Myanmar in Nanning,I would like to express my sincerest congratulations to CAEXPO on reaching the remarkable milestone of over 20 years—an incredible journey filled with numerous achievements.展开更多
BACKGROUND The coronavirus disease 2019(COVID-19)outbreak lasted several months,having started in December 2019.This study aimed to report the impacts of various factors on the depression levels of the general public ...BACKGROUND The coronavirus disease 2019(COVID-19)outbreak lasted several months,having started in December 2019.This study aimed to report the impacts of various factors on the depression levels of the general public and ascertain how emotional measures could be affected by psychosocial factors during the COVID-19 pandemic.AIM To investigate the depression levels of the general public in China during the COVID-19 pandemic.METHODS A total of 2001 self-reported questionnaires about Beck Depression Inventory(BDI)were collected on August 22,2022 via the website.Each questionnaire included four levels of depression and other demographic information.The BDI scores and incidences of different depression levels were compared between various groups of respondents.χ2 analysis and the two-tailed t-test were used to assess categorical and continuous data,respectively.Multiple linear regressions and logistic regressions were employed for correlation analysis.RESULTS The averaged BDI score in this study was higher than that for the non-epidemic periods,as reported in previous studies.Even higher BDI scores and incidences of moderate and severe depression were recorded for people who were quarantined for suspected COVID-19 infection,compared to the respondents who were not quarantined.The participants who did not take protective measures were associated with higher BDI scores than those who made efforts to keep themselves relatively safer.Similarly,the people who did not return to work had higher BDI scores compared to those managed to.A significant association existed between the depression levels of the subgroups and each of the factors,except gender and location of residence.However,quarantine was the most relative predictor for depression levels,followed by failure to take preventive measures and losing a partner,either through divorce or death.CONCLUSION Based on these data,psychological interventions for the various subpopulations in the general public can be implemented during and after the COVID-19 pandemic.Other countries can also use the data as a reference.展开更多
Objective:The study aimed to investigate the effect of relaxation techniques in reducing fear and anxiety in patients in need of general surgery.Materials and Methods:This quasi-experimental study with a pre-post cont...Objective:The study aimed to investigate the effect of relaxation techniques in reducing fear and anxiety in patients in need of general surgery.Materials and Methods:This quasi-experimental study with a pre-post control group design was conducted on 120 patients requiring general surgery at Saman Al-Hojjaj Hospital in Sirjan County.Patients were selected using convenience sampling and randomly assigned to the intervention group(n=60)and control group(n=60).The intervention group was taught box breathing and progressive muscle relaxation techniques by a senior psychiatric nursing expert for 15-20 min every 4 h until surgery.The control group received routine care for surgery.Data on fear and anxiety outcomes were collected using the Spielberger State-Trait Anxiety Inventory and the Surgical Fear Questionnaire.Results:The intervention group had a mean total fear score of 29.27±12.69 compared to 37.20±16.39 in the control group(P=0.012),with significant reductions in both short-term(13.57±5.93 vs.15.98±8.90;P=0.209,Cohen’s d=0.32)and long-term(15.70±7.19 vs.21.22±9.11;P=0.001,Cohen’s d=0.66)fear components(total fear:P=0.012,Cohen’s d=0.54).The total anxiety score was 91.88±6.28 in the control group and 93.60±3.62 in the intervention group,with trait anxiety significantly reduced in the intervention group(P=0.039,Cohen’s d=0.41)postintervention,but no significant change in state anxiety(P=0.577,Cohen’s d=0.16).Conclusions:Relaxation techniques significantly alleviate preoperative psychological distress,effectively reducing fear and anxiety in general surgery patients.These cost-effective,non-invasive methods enhance recovery and reduce healthcare costs.We recommend training healthcare providers to implement these techniques for optimal patient outcomes.展开更多
Objective:This study aims to investigate the cognitive status of community medical staff and patients in Neijiang City towards general practitioners,and analyze the current cognitive status,cognitive needs,and the imp...Objective:This study aims to investigate the cognitive status of community medical staff and patients in Neijiang City towards general practitioners,and analyze the current cognitive status,cognitive needs,and the importance of knowledge dissemination and intervention regarding general practitioners.Methods:A total of 50 community medical staff and patients in Neijiang City were selected for a questionnaire survey conducted from April 2023 to March 2025.A self-designed questionnaire on the concepts of multimorbidity and general practitioners was employed,and the survey was carried out twice,before and after the dissemination of general practice knowledge.Based on the demographic characteristics of the participants and the differences in survey results before and after the knowledge dissemination,the influencing factors and cognitive needs of community medical staff and patients towards general practitioners at this stage were analyzed.Results:Individuals under the age of 35 acquired knowledge mainly through community education(50.00%)and electronic media(50.00%),while those aged 35-65 and over 65 primarily learned through peers,accounting for 57.14%and 48.72%,respectively.After general practice education,among individuals aged≤65,those with a college degree or higher demonstrated higher rates of multimorbidity and met the criteria for family doctor awareness compared to those aged>65 with a high school diploma or lower,with statistically significant differences(p<0.05).Logistic regression analysis revealed that educational attainment(college degree or higher)served as a protective factor for high awareness levels among general practitioners,while age(>65 years)emerged as a risk factor for high awareness levels among general practitioners,with statistically significant differences(p<0.05).Conclusion:To enhance the knowledge and awareness levels of general practitioners among community medical staff and patients,it is imperative to actively expand channels for proactive acquisition of relevant knowledge through education and outreach.Additionally,targeted educational efforts should be intensified for individuals with lower educational attainment and older age groups to establish a public awareness foundation for the effective promotion of general practitioner-led healthcare initiatives at the grassroots level.展开更多
Primary healthcare service is the first line of defense to guard the health of the nation,and traditional Chinese medicine(TCM),with its characteristics of“simplicity,testing and inexpensiveness,”holistic outlook,an...Primary healthcare service is the first line of defense to guard the health of the nation,and traditional Chinese medicine(TCM),with its characteristics of“simplicity,testing and inexpensiveness,”holistic outlook,and the concept of treating the disease before it occurs,has a unique advantage in primary healthcare and a great demand for it.This paper analyzes the core challenges facing the cultivation of general medicine talents in TCM colleges and universities,such as the disconnection between cultivation goals and grassroots,the misalignment between practical ability and grassroots demand,and the lack of career attraction.On this basis,it puts forward a systematic reform path with the core concept of“rooting at the grassroots,highlighting characteristics,and strengthening competence”to cultivate talents that meet grassroots needs,aiming to provide theoretical references for TCM colleges and universities to cultivate excellent TCM talents who are“able to go down to the grassroots,be useful,stay in the field,and have development”,and to provide theoretical reference for the training of excellent TCM talents.The aim is to provide a theoretical reference for Chinese medicine colleges to cultivate excellent Chinese medicine talents who can“get down,use,stay and develop,”and to help the construction of a healthy China.展开更多
The construction of new medicine is a strategic plan proposed by the Party and the state for the development of medical education in the new era,which brings new opportunities and challenges to the cultivation of gene...The construction of new medicine is a strategic plan proposed by the Party and the state for the development of medical education in the new era,which brings new opportunities and challenges to the cultivation of general medical talents.Based on the connotation of the new medical construction,we will promote the construction of a comprehensive medical talent training system.By creating a characteristic general education curriculum system,building a high-level clinical practice teaching base,creating an innovation and entrepreneurship education platform for the First Affiliated Hospital of Xi’an Medical University,and reforming and improving the internal incentive mechanism for teachers,we aim to cultivate comprehensive medical talents who are“useful,competent,capable,and able to stay,”and contribute to the construction of a healthy China.展开更多
The paper is devoted to the study of the gravitational collapse within the framework of the spherically symmetric problem in the Newton theory and general relativity on the basis of the pressure-free model of the cont...The paper is devoted to the study of the gravitational collapse within the framework of the spherically symmetric problem in the Newton theory and general relativity on the basis of the pressure-free model of the continuum. In application to the Newton gravitation theory, the analysis consists of three stages. First, we assume that the gravitational force is determined by the initial sphere radius and constant density and does not change in the process of the sphere collapse. The obtained analytical solution allows us to find the collapse time in the first approximation. Second, we construct the step-by-step process in which the gravitational force at a given time moment depends on the current sphere radius and density. The obtained numerical solution specifies the collapse time depending on the number of steps. Third, we find the exact value of the collapse time which is the limit of the step-by-step solutions and study the collapse and the expansion processes in the Newton theory. In application to general relativity, we use the space model corresponding to the special four-dimensional space which is Euclidean with respect to space coordinates and Riemannian with respect to the time coordinate only. The obtained solution specifies two possible scenarios. First, sphere contraction results in the infinitely high density with the finite collapse time, which does not coincide with the conventional result corresponding to the Schwarzschild geometry. Second, sphere expansion with the velocity which increases with a distance from the sphere center and decreases with time.展开更多
Objective:To investigate the suppressive effect of dexmedetomidine on the cough reflex during tracheal extubation in pediatric patients undergoing general anesthesia and its impact on vital signs.Methods:A total of 60...Objective:To investigate the suppressive effect of dexmedetomidine on the cough reflex during tracheal extubation in pediatric patients undergoing general anesthesia and its impact on vital signs.Methods:A total of 60 pediatric patients undergoing elective surgery admitted to our hospital from January to August 2025 were selected and randomly divided into an observation group and a control group,with 30 cases in each group,using a random number table method.The control group received an intravenous infusion of 0.9% sodium chloride injection 30 minutes before the end of surgery,while the observation group received an intravenous pump infusion of dexmedetomidine(1μg/kg,diluted to 4μg/ml with normal saline).The severity of cough(graded from 0 to 3)and vital signs,including heart rate(HR),systolic blood pressure(SBP),diastolic blood pressure(DBP),and pulse oxygen saturation(SpO₂),were recorded 5 minutes before extubation,at the time of extubation,and 5 minutes after extubation in both groups.Results:The severity of cough in the observation group was significantly milder than that in the control group(P<0.05),with a significantly higher proportion of grade 0 cough in the observation group(23.33%vs 3.33%).At extubation and five minutes post-extubation,the observation group exhibited significantly lower HR,SBP,and DBP than the control group(P<0.05).In contrast,SpO_(2)levels remained comparable between the groups(P>0.05).Conclusion:Dexmedetomidine can effectively suppress the cough reflex during tracheal extubation in pediatric patients undergoing general anesthesia,reduce the severity of cough,stabilize hemodynamic parameters,and has no significant impact on respiratory function,demonstrating good clinical safety.展开更多
基金funded by the China National Space Administration(KJSP2023020105)supported by the National Key R&D Program of China(Grant No.2023YFA1608100)+2 种基金the NSFC(Grant No.62227901)the Minor Planet Foundationsupported by the Egyptian Science,Technology&Innovation Funding Authority(STDF)under Grant No.48102.
文摘Near-Earth objects are important not only in studying the early formation of the Solar System,but also because they pose a serious hazard to humanity when they make close approaches to the Earth.Study of their physical properties can provide useful information on their origin,evolution,and hazard to human beings.However,it remains challenging to investigate small,newly discovered,near-Earth objects because of our limited observational window.This investigation seeks to determine the visible colors of near-Earth asteroids(NEAs),perform an initial taxonomic classification based on visible colors and analyze possible correlations between the distribution of taxonomic classification and asteroid size or orbital parameters.Observations were performed in the broadband BVRI Johnson−Cousins photometric system,applied to images from the Yaoan High Precision Telescope and the 1.88 m telescope at the Kottamia Astronomical Observatory.We present new photometric observations of 84 near-Earth asteroids,and classify 80 of them taxonomically,based on their photometric colors.We find that nearly half(46.3%)of the objects in our sample can be classified as S-complex,26.3%as C-complex,6%as D-complex,and 15.0%as X-complex;the remaining belong to the A-or V-types.Additionally,we identify three P-type NEAs in our sample,according to the Tholen scheme.The fractional abundances of the C/X-complex members with absolute magnitude H≥17.0 were more than twice as large as those with H<17.0.However,the fractions of C-and S-complex members with diameters≤1 km and>1 km are nearly equal,while X-complex members tend to have sub-kilometer diameters.In our sample,the C/D-complex objects are predominant among those with a Jovian Tisserand parameter of T_(J)<3.1.These bodies could have a cometary origin.C-and S-complex members account for a considerable proportion of the asteroids that are potentially hazardous.
基金supports from the National Natural Science Foundation of China(NSFC,grant Nos.12203002 and 11973015)supports from the National Key Basic R&D Program of China via 2023YFA1608303 and the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB0550103)+6 种基金supports from the National Natural Science Foundation of China(NSFCgrant No.12373015)supports from the National Natural Science Foundation of China(NSFCgrant Nos.12120101003 and 12373010)National Key R&D Program of China(grant Nos.2023YFA1607800,2023YFA1607804,2022YFA1602902)Beijing Municipal Natural Science Foundation(grant No.1222028)Strategic Priority Research Program of the Chinese Academy of Science(grant Nos.XDB0550100 and XDB0550000).
文摘The SiTian project,with its vast field of view,will become an ideal platform for scientific research on asteroids.In this study,we develop a pipeline to analyze the photometry of asteroids and derive their periods from the data collected by the SiTian pathfinder project Mini-SiTian(MST).The pipeline is applied to the MST f02 region,an MST test region with a sky area of 2°.29×1°.53.Rotation periods of 22 asteroids are derived by the obtained light curve analysis.Among them,there are eight asteroids available in the Asteroid Lightcurve Photometry Database(ALCDEF),and six of them with more photometric points(>200)that have similar period parameters as the ones in ALCDEF.Additionally,the periods for 14 of these asteroids are newly obtained and are not listed in ALCDEF.This study demonstrates the feasibility of asteroid photometric research by the SiTian project.It shows that future observations from the SiTian project will provide even more photometry of asteroids,significantly increasing the number of available light curves.The potential vast photometric data on asteroids will help us to further understand the physics of asteroids,their material composition,and the formation and evolution of the solar system.
文摘BACKGROUND Currently,very few studies have examined the analgesic effectiveness and safety of dexmedetomidine-assisted intravenous-inhalation combined general anesthesia in laparoscopic minimally invasive surgery for inguinal hernia.AIM To investigate the analgesic effect and safety of dexmedetomidine-assisted intravenous-inhalation combined general anesthesia in laparoscopic minimally invasive surgery for inguinal hernia.METHODS In this retrospective study,94 patients scheduled for laparoscopic minimally invasive surgery for inguinal hernia,admitted to Yiwu Central Hospital between May 2022 and May 2023,were divided into a control group(inhalation combined general anesthesia)and a treatment group(dexmedetomidine-assisted intrave-nous-inhalation combined general anesthesia).Perioperative indicators,analgesic effect,preoperative and postoperative 24-hours blood pressure(BP)and heart rate(HR),stress indicators,immune function levels,and adverse reactions were com-pared between the two groups.RESULTS Baseline data,including age,hernia location,place of residence,weight,monthly income,education level,and underlying diseases,were not significantly different between the two groups,indicating comparability(P>0.05).No significant difference was found in operation time and anesthesia time between the two groups(P>0.05).However,the treatment group exhibited a shorter postoperative urinary catheter removal time and hospital stay than the control group(P<0.05).Preoperatively,no significant differences were found in the visual analog scale(VAS)scores between the two groups(P>0.05).However,at 12,18,and 24 hours postoper-atively,the treatment group had significantly lower VAS scores than the control group(P<0.05).Although no significant differences in preoperative hemodynamic indicators were found between the two groups(P>0.05),both groups experienced some extent of changes in postoperative HR,diastolic BP(DBP),and systolic BP(SBP).Nevertheless,the treatment group showed smaller changes in HR,DBP,and SBP than the control group(P<0.05).Preoperative immune function indicators showed no significant differences between the two groups(P>0.05).However,postoperatively,the treatment group demonstrated higher levels of CD3+,CD4+,and CD4+/CD8+and lower levels of CD8+than the control group(P<0.05).The rates of adverse reactions were 6.38%and 23.40%in the treatment and control groups,respectively,revealing a significant difference(χ2=5.371,P=0.020).CONCLUSION Dexmedetomidine-assisted intravenous-inhalation combined general anesthesia can promote early recovery of patients undergoing laparoscopic minimally invasive surgery for inguinal hernia.It ensures stable blood flow,improves postoperative analgesic effects,reduces postoperative pain intensity,alleviates stress response,improves immune function,facilitates anesthesia recovery,and enhances safety.
基金funded by Centre for Advanced Modelling and Geospatial Information Systems(CAMGIS),Faculty of Engineering and IT,University of Technology Sydney.Moreover,Ongoing Research Funding Program(ORF-2025-14)King Saud University,Riyadh,Saudi Arabia,under Project ORF-2025-。
文摘Face liveness detection is essential for securing biometric authentication systems against spoofing attacks,including printed photos,replay videos,and 3D masks.This study systematically evaluates pre-trained CNN models—DenseNet201,VGG16,InceptionV3,ResNet50,VGG19,MobileNetV2,Xception,and InceptionResNetV2—leveraging transfer learning and fine-tuning to enhance liveness detection performance.The models were trained and tested on NUAA and Replay-Attack datasets,with cross-dataset generalization validated on SiW-MV2 to assess real-world adaptability.Performance was evaluated using accuracy,precision,recall,FAR,FRR,HTER,and specialized spoof detection metrics(APCER,NPCER,ACER).Fine-tuning significantly improved detection accuracy,with DenseNet201 achieving the highest performance(98.5%on NUAA,97.71%on Replay-Attack),while MobileNetV2 proved the most efficient model for real-time applications(latency:15 ms,memory usage:45 MB,energy consumption:30 mJ).A statistical significance analysis(paired t-tests,confidence intervals)validated these improvements.Cross-dataset experiments identified DenseNet201 and MobileNetV2 as the most generalizable architectures,with DenseNet201 achieving 86.4%accuracy on Replay-Attack when trained on NUAA,demonstrating robust feature extraction and adaptability.In contrast,ResNet50 showed lower generalization capabilities,struggling with dataset variability and complex spoofing attacks.These findings suggest that MobileNetV2 is well-suited for low-power applications,while DenseNet201 is ideal for high-security environments requiring superior accuracy.This research provides a framework for improving real-time face liveness detection,enhancing biometric security,and guiding future advancements in AI-driven anti-spoofing techniques.
文摘Retinal blood vessel segmentation is crucial for diagnosing ocular and cardiovascular diseases.Although the introduction of U-Net in 2015 by Olaf Ronneberger significantly advanced this field,yet issues like limited training data,imbalance data distribution,and inadequate feature extraction persist,hindering both the segmentation performance and optimal model generalization.Addressing these critical issues,the DEFFA-Unet is proposed featuring an additional encoder to process domain-invariant pre-processed inputs,thereby improving both richer feature encoding and enhanced model generalization.A feature filtering fusion module is developed to ensure the precise feature filtering and robust hybrid feature fusion.In response to the task-specific need for higher precision where false positives are very costly,traditional skip connections are replaced with the attention-guided feature reconstructing fusion module.Additionally,innovative data augmentation and balancing methods are proposed to counter data scarcity and distribution imbalance,further boosting the robustness and generalization of the model.With a comprehensive suite of evaluation metrics,extensive validations on four benchmark datasets(DRIVE,CHASEDB1,STARE,and HRF)and an SLO dataset(IOSTAR),demonstrate the proposed method’s superiority over both baseline and state-of-the-art models.Particularly the proposed method significantly outperforms the compared methods in cross-validation model generalization.
基金supported by the National Key Research and Development Program of China(No.2019YFA0706500)。
文摘Flexible lander,composed of multiple nodes connected by flexible material,can reducethe bouncing and overturning during the asteroid landing.To satisfy the complex constraints inthe node cooperation of the flexible landing,an intelligent cooperative guidance method is pro-posed.The method consists of a double-layer cooperative guidance structure,a guidance parameterdetermination approach,and an action priority strategy.The double-layer contains a basic guid-ance used to satisfy the terminal state constraints,and a compensatory guidance used to satisfythe lander's attitude constraint.For the compensatory guidance,the parameters are determinedby multi-agent system,which are trained according to the performance index of flexible landing tra-jectories.The action priority strategy is used to reduce the detrimental effect of parameter inconsis-tency on the node cooperation.The simulation of flexible landing shows that the cooperativeguidance method is effective in improving the landing accuracy while satisfying the constraints.Meanwhile,the method is robust to the disturbance in the navigation and control.
文摘The US 2024 general election ended with the Republican Party winning the presidential, House and Senate elections at the same time. In the presidential election, the Republican Party not only won more popular votes in over 90% counties than in the 2020 general election, but also won seven highly contested swing States with greater edges. This also marks the first time since 2004 that the Republican Party has won a relative majority of popular votes in the presidential election.
基金supported by the Special Funding Project for Space Debris and Near-Earth Asteroids Defense Research, China (No. KJSP2023020303)Beijing Municipal Science and Technology Commission, China (No. Z181100002918004)the Youth Innovation Promotion Association, Chinese Academy of Sciences (No. 2022146)
文摘Implementing the flyby to Near-Earth Asteroids (NEAs) with the potential impact risks to the Earth allows for obtaining detailed physical parameters, thereby supporting the high-precision orbit prediction and planetary defense strategy. Different from those conducted asteroid flyby missions, in the 12th China Trajectory Optimization Competition (CTOC-12), a NEAs flyby trajectory design problem using reusable probes that depart from a Lunar Distant Retrograde Orbit (DRO) station in the cislunar space was released. The objective was flyby to as many NEAs as possible using up to 20 probes within a total of 10 years. The ∑ team proposed a solution that can explore 47 NEAs using 11 probes, ranking the first in the competition. In this paper, the methods and results from the winning team are introduced, including mission analysis and preliminary design, and low-energy transfer trajectory optimization. In particular, a round-trip trajectory is divided into three phases: deep space transfer, indirect transfer between the Earth to DRO, and DRO phasing and rendezvous. With the combination of global optimization and local optimization algorithms, the required velocity increments to change the orbital planes are effectively reduced, thus increasing the number of the explored NEAs. The final solution of our team is presented and the results are compared with those of the top three teams. The competition demonstrates that the regularization of flyby missions from the cislunar space to explore NEAs with the potential impact risks to the Earth is the feasible and promising.
基金supported in part by the 2024 Core General Education Course Construction Project of Beijing Union University,titled“Cybersecurity:Exploring the World of White Hat Hackers”the 2025 Educational Science Research Project of Beijing Union University(JK202514)+1 种基金the General Project of Science and Technology Program of Beijing Municipal Education Commission under Grant KM201911417011the Academic Research Projects of Beijing Union University(ZK30202407).
文摘Strengthening cybersecurity education for college students holds significant importance in achieving the strategic goal of building China into a cyber power.This article begins by discussing the significance and necessity of implementing cybersecurity education for university students.Drawing on disciplinary characteristics and student learning analysis,it presents a comprehensive construction process and countermeasures for a general cybersecurity education course,covering aspects such as teaching content development,teaching resource creation,and pedagogical approaches.The aim is to provide reference and guidance for other universities in developing general cybersecurity education courses.
文摘Digital twin shows broad application prospects in the aerospace field.This paper introduces a generalized satellite digital twin system in detail.With the innovative design concepts of modularization,generalization and modeling,on the one hand,the system has successfully achieved the reuse of software modules among different satellite models;on the other hand,it has achieved the reuse of software modules between the digital twin and the testing system,significantly improving the development efficiency of the digital twin system.The paper elaborates on the technical architecture and application fields of this digital twin system,and further prospects its future development.At the same time,through a real inorbit case,the engineering value of the digital twin system is strongly demonstrated.
基金supported by the Shandong Provincial Natural Science Foundation(ZR2022QH144).
文摘The phenomenon of fear memory generalization can be defined as the expansion of an individual's originally specific fear responses to a similar yet genuinely harmless stimulus or situation subsequent to the occurrence of a traumatic event[1].Fear generalization within the normal range represents an adaptive evolutionary mechanism to facilitate prompt reactions to potential threats and to enhance the likelihood of survival.
基金Supported by the National Key R&D Program of China(No.2023YFB4502200)the National Natural Science Foundation of China(No.U22A2028,61925208,62222214,62341411,62102398,62102399,U20A20227,62302478,62302482,62302483,62302480,62302481)+2 种基金the Strategic Priority Research Program of the Chinese Academy of Sciences(No.XDB0660300,XDB0660301,XDB0660302)the Chinese Academy of Sciences Project for Young Scientists in Basic Research(No.YSBR-029)the Youth Innovation Promotion Association of Chinese Academy of Sciences and Xplore Prize.
文摘The challenge of enhancing the generalization capacity of reinforcement learning(RL)agents remains a formidable obstacle.Existing RL methods,despite achieving superhuman performance on certain benchmarks,often struggle with this aspect.A potential reason is that the benchmarks used for training and evaluation may not adequately offer a diverse set of transferable tasks.Although recent studies have developed bench-marking environments to address this shortcoming,they typically fall short in providing tasks that both ensure a solid foundation for generalization and exhibit significant variability.To overcome these limitations,this work introduces the concept that‘objects are composed of more fundamental components’in environment design,as implemented in the proposed environment called summon the magic(StM).This environment generates tasks where objects are derived from extensible and shareable basic components,facilitating strategy reuse and enhancing generalization.Furthermore,two new metrics,adaptation sensitivity range(ASR)and parameter correlation coefficient(PCC),are proposed to better capture and evaluate the generalization process of RL agents.Experimental results show that increasing the number of basic components of the object reduces the proximal policy optimization(PPO)agent’s training-testing gap by 60.9%(in episode reward),significantly alleviating overfitting.Additionally,linear variations in other environmental factors,such as the training monster set proportion and the total number of basic components,uniformly decrease the gap by at least 32.1%.These results highlight StM’s effectiveness in benchmarking and probing the generalization capabilities of RL algorithms.
文摘Mingalarpar!On behalf of the Consulate-General of the Republic of the Union of Myanmar in Nanning,I would like to express my sincerest congratulations to CAEXPO on reaching the remarkable milestone of over 20 years—an incredible journey filled with numerous achievements.
文摘BACKGROUND The coronavirus disease 2019(COVID-19)outbreak lasted several months,having started in December 2019.This study aimed to report the impacts of various factors on the depression levels of the general public and ascertain how emotional measures could be affected by psychosocial factors during the COVID-19 pandemic.AIM To investigate the depression levels of the general public in China during the COVID-19 pandemic.METHODS A total of 2001 self-reported questionnaires about Beck Depression Inventory(BDI)were collected on August 22,2022 via the website.Each questionnaire included four levels of depression and other demographic information.The BDI scores and incidences of different depression levels were compared between various groups of respondents.χ2 analysis and the two-tailed t-test were used to assess categorical and continuous data,respectively.Multiple linear regressions and logistic regressions were employed for correlation analysis.RESULTS The averaged BDI score in this study was higher than that for the non-epidemic periods,as reported in previous studies.Even higher BDI scores and incidences of moderate and severe depression were recorded for people who were quarantined for suspected COVID-19 infection,compared to the respondents who were not quarantined.The participants who did not take protective measures were associated with higher BDI scores than those who made efforts to keep themselves relatively safer.Similarly,the people who did not return to work had higher BDI scores compared to those managed to.A significant association existed between the depression levels of the subgroups and each of the factors,except gender and location of residence.However,quarantine was the most relative predictor for depression levels,followed by failure to take preventive measures and losing a partner,either through divorce or death.CONCLUSION Based on these data,psychological interventions for the various subpopulations in the general public can be implemented during and after the COVID-19 pandemic.Other countries can also use the data as a reference.
基金funded by Sirjan Medical Sciences Faculty,Sirjan,Iran.(Project code:402000018).
文摘Objective:The study aimed to investigate the effect of relaxation techniques in reducing fear and anxiety in patients in need of general surgery.Materials and Methods:This quasi-experimental study with a pre-post control group design was conducted on 120 patients requiring general surgery at Saman Al-Hojjaj Hospital in Sirjan County.Patients were selected using convenience sampling and randomly assigned to the intervention group(n=60)and control group(n=60).The intervention group was taught box breathing and progressive muscle relaxation techniques by a senior psychiatric nursing expert for 15-20 min every 4 h until surgery.The control group received routine care for surgery.Data on fear and anxiety outcomes were collected using the Spielberger State-Trait Anxiety Inventory and the Surgical Fear Questionnaire.Results:The intervention group had a mean total fear score of 29.27±12.69 compared to 37.20±16.39 in the control group(P=0.012),with significant reductions in both short-term(13.57±5.93 vs.15.98±8.90;P=0.209,Cohen’s d=0.32)and long-term(15.70±7.19 vs.21.22±9.11;P=0.001,Cohen’s d=0.66)fear components(total fear:P=0.012,Cohen’s d=0.54).The total anxiety score was 91.88±6.28 in the control group and 93.60±3.62 in the intervention group,with trait anxiety significantly reduced in the intervention group(P=0.039,Cohen’s d=0.41)postintervention,but no significant change in state anxiety(P=0.577,Cohen’s d=0.16).Conclusions:Relaxation techniques significantly alleviate preoperative psychological distress,effectively reducing fear and anxiety in general surgery patients.These cost-effective,non-invasive methods enhance recovery and reduce healthcare costs.We recommend training healthcare providers to implement these techniques for optimal patient outcomes.
文摘Objective:This study aims to investigate the cognitive status of community medical staff and patients in Neijiang City towards general practitioners,and analyze the current cognitive status,cognitive needs,and the importance of knowledge dissemination and intervention regarding general practitioners.Methods:A total of 50 community medical staff and patients in Neijiang City were selected for a questionnaire survey conducted from April 2023 to March 2025.A self-designed questionnaire on the concepts of multimorbidity and general practitioners was employed,and the survey was carried out twice,before and after the dissemination of general practice knowledge.Based on the demographic characteristics of the participants and the differences in survey results before and after the knowledge dissemination,the influencing factors and cognitive needs of community medical staff and patients towards general practitioners at this stage were analyzed.Results:Individuals under the age of 35 acquired knowledge mainly through community education(50.00%)and electronic media(50.00%),while those aged 35-65 and over 65 primarily learned through peers,accounting for 57.14%and 48.72%,respectively.After general practice education,among individuals aged≤65,those with a college degree or higher demonstrated higher rates of multimorbidity and met the criteria for family doctor awareness compared to those aged>65 with a high school diploma or lower,with statistically significant differences(p<0.05).Logistic regression analysis revealed that educational attainment(college degree or higher)served as a protective factor for high awareness levels among general practitioners,while age(>65 years)emerged as a risk factor for high awareness levels among general practitioners,with statistically significant differences(p<0.05).Conclusion:To enhance the knowledge and awareness levels of general practitioners among community medical staff and patients,it is imperative to actively expand channels for proactive acquisition of relevant knowledge through education and outreach.Additionally,targeted educational efforts should be intensified for individuals with lower educational attainment and older age groups to establish a public awareness foundation for the effective promotion of general practitioner-led healthcare initiatives at the grassroots level.
文摘Primary healthcare service is the first line of defense to guard the health of the nation,and traditional Chinese medicine(TCM),with its characteristics of“simplicity,testing and inexpensiveness,”holistic outlook,and the concept of treating the disease before it occurs,has a unique advantage in primary healthcare and a great demand for it.This paper analyzes the core challenges facing the cultivation of general medicine talents in TCM colleges and universities,such as the disconnection between cultivation goals and grassroots,the misalignment between practical ability and grassroots demand,and the lack of career attraction.On this basis,it puts forward a systematic reform path with the core concept of“rooting at the grassroots,highlighting characteristics,and strengthening competence”to cultivate talents that meet grassroots needs,aiming to provide theoretical references for TCM colleges and universities to cultivate excellent TCM talents who are“able to go down to the grassroots,be useful,stay in the field,and have development”,and to provide theoretical reference for the training of excellent TCM talents.The aim is to provide a theoretical reference for Chinese medicine colleges to cultivate excellent Chinese medicine talents who can“get down,use,stay and develop,”and to help the construction of a healthy China.
基金2024 Education and Teaching Reform Research Project of Xi’an Medical University(JG2024-04):Research on the Training System of Applied,Compound,and Innovative Talents in General Practice under the Background of New Medicine2024 Innovation and Entrepreneurship Education Reform Special Project of Xi’an Medical University(2024CCJG-01):Research on the Construction of Innovation and Entrepreneurship Talent Training Model Based on the“Innovation and Entrepreneurship Education Platform”。
文摘The construction of new medicine is a strategic plan proposed by the Party and the state for the development of medical education in the new era,which brings new opportunities and challenges to the cultivation of general medical talents.Based on the connotation of the new medical construction,we will promote the construction of a comprehensive medical talent training system.By creating a characteristic general education curriculum system,building a high-level clinical practice teaching base,creating an innovation and entrepreneurship education platform for the First Affiliated Hospital of Xi’an Medical University,and reforming and improving the internal incentive mechanism for teachers,we aim to cultivate comprehensive medical talents who are“useful,competent,capable,and able to stay,”and contribute to the construction of a healthy China.
文摘The paper is devoted to the study of the gravitational collapse within the framework of the spherically symmetric problem in the Newton theory and general relativity on the basis of the pressure-free model of the continuum. In application to the Newton gravitation theory, the analysis consists of three stages. First, we assume that the gravitational force is determined by the initial sphere radius and constant density and does not change in the process of the sphere collapse. The obtained analytical solution allows us to find the collapse time in the first approximation. Second, we construct the step-by-step process in which the gravitational force at a given time moment depends on the current sphere radius and density. The obtained numerical solution specifies the collapse time depending on the number of steps. Third, we find the exact value of the collapse time which is the limit of the step-by-step solutions and study the collapse and the expansion processes in the Newton theory. In application to general relativity, we use the space model corresponding to the special four-dimensional space which is Euclidean with respect to space coordinates and Riemannian with respect to the time coordinate only. The obtained solution specifies two possible scenarios. First, sphere contraction results in the infinitely high density with the finite collapse time, which does not coincide with the conventional result corresponding to the Schwarzschild geometry. Second, sphere expansion with the velocity which increases with a distance from the sphere center and decreases with time.
文摘Objective:To investigate the suppressive effect of dexmedetomidine on the cough reflex during tracheal extubation in pediatric patients undergoing general anesthesia and its impact on vital signs.Methods:A total of 60 pediatric patients undergoing elective surgery admitted to our hospital from January to August 2025 were selected and randomly divided into an observation group and a control group,with 30 cases in each group,using a random number table method.The control group received an intravenous infusion of 0.9% sodium chloride injection 30 minutes before the end of surgery,while the observation group received an intravenous pump infusion of dexmedetomidine(1μg/kg,diluted to 4μg/ml with normal saline).The severity of cough(graded from 0 to 3)and vital signs,including heart rate(HR),systolic blood pressure(SBP),diastolic blood pressure(DBP),and pulse oxygen saturation(SpO₂),were recorded 5 minutes before extubation,at the time of extubation,and 5 minutes after extubation in both groups.Results:The severity of cough in the observation group was significantly milder than that in the control group(P<0.05),with a significantly higher proportion of grade 0 cough in the observation group(23.33%vs 3.33%).At extubation and five minutes post-extubation,the observation group exhibited significantly lower HR,SBP,and DBP than the control group(P<0.05).In contrast,SpO_(2)levels remained comparable between the groups(P>0.05).Conclusion:Dexmedetomidine can effectively suppress the cough reflex during tracheal extubation in pediatric patients undergoing general anesthesia,reduce the severity of cough,stabilize hemodynamic parameters,and has no significant impact on respiratory function,demonstrating good clinical safety.
