Cases of widespread bone hydatid infection are relatively rare in clinical practice.In this study,we reported for the first time a validated integrated repair therapy for multiple bone tissues,including the hip,femur,...Cases of widespread bone hydatid infection are relatively rare in clinical practice.In this study,we reported for the first time a validated integrated repair therapy for multiple bone tissues,including the hip,femur,and knee,caused by echinococ cosis.Artificial intelligence(AI)was used to develop a targeted surgical plan and to design a personalized prosthesis.Finite element analysis(FEA)was used to optimize the mechanical effectiveness of a customized integrated replacement prosthesis and to model stress distribution in the surrounding bone.Three-dimensional(3 D)printing was used to fabricate a customized prosthesis.With the assistance of AI,FEA,and 3 D printing technology,a personalized surgical plan and customized prosthesis were successfully constructed based on the patient’s disease.This approach achieved a successful therapeutic effect,demonstrating that AI-assisted personalized medicine holds great promise for the future.展开更多
The central treasury is implementing six measures this year to help small-and medium-sized enterprises (SMEs) meet the challenges they face, according to the Ministry of Finance.
The intricately complex structures of natural biological materials,which endow them with exceptional properties,serve as unparalleled models and sources of inspiration for the design of synthetic materials.However,tra...The intricately complex structures of natural biological materials,which endow them with exceptional properties,serve as unparalleled models and sources of inspiration for the design of synthetic materials.However,translating these structures into metallic systems poses formidable challenges due to the demanding conditions required for metal processing.This brief perspective spotlights the 3D interpenetrating‐phase structures evolved in biological materials and distills key insights for bioinspired structural design in metallic materials.We highlight recent advancements in creating bioinspired metal composites,particularly through advanced processing techniques like metal melt infiltration into porous scaffolds,achieving remarkable synergies between various mechanical properties and functionalities.Additionally,AI‐driven approaches show immense potential to accelerate the iterative process of optimizing structures and properties in bioinspired designs.展开更多
基金partially supported by the National Natural Science Foundation of China(Nos.32471474 and 82102574)the Precision Medicine Project of People’s Hospital of Xinjiang Uygur Autonomous Region(No.20220305)+4 种基金Chengdu Advanced Metal Materials Industry Technology Research Institute Co.,Ltd.Support Project(No.24H0802)Sichuan Science and Technology Program(Nos.2025YFHZ0086,2023YFS0053,2024YFHZ0125,and 2025ZNSFSC0381)Project of Tianfu Jincheng Laboratory(No.2025ZH009)Guangdong Basic and Applied Basic Research Foundation(No.2023A1515220102)Xinjiang Autonomous Region Science and Technology Support Project Plan(Directive)Project(No.2024E02049)。
文摘Cases of widespread bone hydatid infection are relatively rare in clinical practice.In this study,we reported for the first time a validated integrated repair therapy for multiple bone tissues,including the hip,femur,and knee,caused by echinococ cosis.Artificial intelligence(AI)was used to develop a targeted surgical plan and to design a personalized prosthesis.Finite element analysis(FEA)was used to optimize the mechanical effectiveness of a customized integrated replacement prosthesis and to model stress distribution in the surrounding bone.Three-dimensional(3 D)printing was used to fabricate a customized prosthesis.With the assistance of AI,FEA,and 3 D printing technology,a personalized surgical plan and customized prosthesis were successfully constructed based on the patient’s disease.This approach achieved a successful therapeutic effect,demonstrating that AI-assisted personalized medicine holds great promise for the future.
文摘The central treasury is implementing six measures this year to help small-and medium-sized enterprises (SMEs) meet the challenges they face, according to the Ministry of Finance.
基金support by the National Key R&D Program of China(2020YFA0710404)the National Natural Science Foundation of China(52471152,52173269 and 52321001)+2 种基金the Youth Innovation Promotion Association CAS(2019191)the Multi‐University Research Initiative(AFOSR‐FA9550‐15‐1‐0009)from the Air Force Office of Scientific ResearchShaanxi Qinchuangyuan Cited Highlevel Innovation and Entrepreneurial Talents Project(2025RC‐YJRC‐029).
文摘The intricately complex structures of natural biological materials,which endow them with exceptional properties,serve as unparalleled models and sources of inspiration for the design of synthetic materials.However,translating these structures into metallic systems poses formidable challenges due to the demanding conditions required for metal processing.This brief perspective spotlights the 3D interpenetrating‐phase structures evolved in biological materials and distills key insights for bioinspired structural design in metallic materials.We highlight recent advancements in creating bioinspired metal composites,particularly through advanced processing techniques like metal melt infiltration into porous scaffolds,achieving remarkable synergies between various mechanical properties and functionalities.Additionally,AI‐driven approaches show immense potential to accelerate the iterative process of optimizing structures and properties in bioinspired designs.
