Near-infrared(NIR)light-triggered pyroptosis based on biocompatible Pt(IV)-coordinated nanomedicine for tumor precision therapy is challenging.Here,we disclose a supramolecular approach to construct a hollow-spherical...Near-infrared(NIR)light-triggered pyroptosis based on biocompatible Pt(IV)-coordinated nanomedicine for tumor precision therapy is challenging.Here,we disclose a supramolecular approach to construct a hollow-spherical supra-(carbon dots)(HS-Pt-CDs)via ultrasound-assisted J-type assembly of Pt(IV)-coordinated carbon dots(Pt-CDs).The peculiar assembling behaviors arise from the steric hindrance and lattice distortion in the bowl-like Pt-CDs caused by the coordination of Pt(IV)atoms among the sp^(2)domains,which result in around 240 nm red-shifted absorption bands and promoting charge separation in the NIR region due to strong inter-molecular charge transfer(CT)in HS-Pt-CDs.The results reveal that HS-Pt-CDs exhibit excellent NIR light-activated photocatalytic capacities,involving the release of Pt(II)species,the generation of hydroxyl radicals,and acidification under 690 nm laser irradiation.Combined with the effective cellular uptake and tumor accumulation,HS-Pt-CDs can efficiently trigger cancer cell pyroptosis under 690 nm laser irradiation,resulting in the destruction of the primary tumor and effectively induction of strong immunogenic cell death(ICD),thereby evoking anti-tumor immune responses to suppress distant tumor and prevent cancer metastasis.Taken these merits,an important perspective of Pt(IV)-contained supra-CDs with outstanding NIRtriggered photocatalytic behaviors can be of great significance toward precision tumor phototherapy.展开更多
The construction of modern cities emphasizes the nature and harmony among the“people”,“things”and“environment”,reflecting the harmony and unity of the formal beauty,functional beauty and surrounding environment ...The construction of modern cities emphasizes the nature and harmony among the“people”,“things”and“environment”,reflecting the harmony and unity of the formal beauty,functional beauty and surrounding environment of architecture.Based on the introduction of the design concept of the assembled pedestrian overbridge,through the Jianhua Building Materials Group’s first“pre-fabricated low-rise tower-stayed pedestrian landscape overbridge”project in China,this paper proposes a solution that can improve the landscape design of the overbridge and reduce the construction complexity of the overbridge,the assembly product supply and the construction process“integration”under the premise of ensuring the safety and stability of the pedestrian overbridge,whose prefabricated production and assembly construction,shortening the construction period,reducing energy consumption,reducing pollution,and obtaining good social comprehensive benefits.展开更多
Analyze and compare the basic principles of ultrasonic detection of voids in concrete,choose ZBL-U520/510 non-metallic ultrasonic detector,and use the opposite detection method to test the void size in the joints of p...Analyze and compare the basic principles of ultrasonic detection of voids in concrete,choose ZBL-U520/510 non-metallic ultrasonic detector,and use the opposite detection method to test the void size in the joints of prefabri-cated concrete structures.The results show that:ultrasonic method by testing the waveform,sound,and speed of sound analysis can effectively determine the position of the defect,and through the conversion formula can estimate the void size.Ultrasonic parameters are used to distinguish the internal defects of Assembly concrete.Sometimes there are diferent results with different para-meters.It is difficult for engineers to directly determine the internal de fects.Fuzzy comprehensive ev aluation can establish an overall evaluation of things or objects controlled by multiple factors by establishing membership functions.Through the inspection of engineering examples:the fuzzy comprehensive judgment method has no difference between the judgment of some good quality points and the judg-ment results of the original criteria,but for some abnormal points or points near the critical value,the advantages of fiuzzy criteria can be achieved.The judgment process will be more scientific by considering several parameters in a comprehen-sive manner and digtizing the original subjective judgments.展开更多
An assembly type flowshop scheduling problem with minimizing makespan is considered in this paper. The problem of scheduling for minimizing makespan is first addressed, and then a new heuristic algorithm is proposed ...An assembly type flowshop scheduling problem with minimizing makespan is considered in this paper. The problem of scheduling for minimizing makespan is first addressed, and then a new heuristic algorithm is proposed for it.展开更多
With the improvement of Chinas urban construction level, the scale of the construction industry is constantly expanding, and the traditional production methods, production techniques and production technologies can no...With the improvement of Chinas urban construction level, the scale of the construction industry is constantly expanding, and the traditional production methods, production techniques and production technologies can no longer adapt to the development of cities. With the continuous development and application of building technology, prefabricated building components and BIM technology, the idea of green, low-carbon, environmental protection and sustainable development has become an inevitable choice to promote the transformation and upgrading of the construction industry. Relevant departments of the state, provinces and cities have issued a series of policies, which have promoted the research and development and engineering practice of prefabricated concrete construction technology, and promoted the application of BIM technology in the whole construction process. Therefore, the application of BIM technology in precast concrete structures has become a research hotspot, combining the two will bring greater economic and social benefits.展开更多
China's continuous economic progress, the deepening process of urbanization, and the gradual improvement of people's living standards have brought more opportunities for the development of the construction ind...China's continuous economic progress, the deepening process of urbanization, and the gradual improvement of people's living standards have brought more opportunities for the development of the construction industry. The number of construction projects is increasing, and the scale of projects is expanding. In order to meet the increasing demand of people for the number of buildings, the construction industry is developing and innovating, and the application of prefabricated building mode comes into being. Building curtain wall is an important part of prefabricated building. Glass curtain wall is widely used in practice. In order to improve the overall quality of prefabricated building engineering and the overall beauty of the building, we should attach great importance to the construction of prefabricated building curtain wall and adopt scientific curtain wall construction technology. Combined with the concept of prefabricated building, this paper deeply analyzes the key points of curtain wall construction technology and the specific application of curtain wall construction method of prefabricated building, which provides valuable reference experience for building a scientific and complete curtain wall construction technology system of prefabricated building, providing technical support for prefabricated building, and promoting the healthy and sustainable development of prefabricated building in China.展开更多
Nowadays, the prefabrication level of bridge engineering is higher and higher, and many prefabricated components are used in construction, such as prefabricated bent cap. Compared with the previous cap beam constructi...Nowadays, the prefabrication level of bridge engineering is higher and higher, and many prefabricated components are used in construction, such as prefabricated bent cap. Compared with the previous cap beam construction technology, the fabricated cap beam can not only ensure the construction quality, but also speed up the construction speed, shorten the construction period, and lay a good foundation for bridge construction. Combined with the construction practice, this paper studies and discusses the important links of prefabricated bridge construction, the installation technology of precast column and the key points of construction quality control, hoping to provide reference for the compilation of relevant construction specifications in the future.展开更多
Prefabricated buildings are the focus of attention and research in Chinas construction field and related industries. Compared with conventional brick-concrete buildings, such buildings have the advantages of less poll...Prefabricated buildings are the focus of attention and research in Chinas construction field and related industries. Compared with conventional brick-concrete buildings, such buildings have the advantages of less pollution, less construction waste and simplified manual operation. However, the main reason for restricting the popularization and use of prefabricated buildings in the market is that the design experience of such buildings is less, that is, the design results often have the problem of node collision during the on-site assembly construction, which not only affects the overall design quality of the building, but also interferes with the subsequent assembly construction of the project. Therefore, it is necessary to comprehensively deepen the design of prefabricated building structure on the basis of existing working technology and information technology.展开更多
With the progress of science and technology, China's industrial development is gradually in the leading position in the world, the country also gradually uses steel structure buildings in the field of construction...With the progress of science and technology, China's industrial development is gradually in the leading position in the world, the country also gradually uses steel structure buildings in the field of construction, and according to the actual situation and people's needs, constantly improve the design and construction, adhere to the road of sustainable development.展开更多
基金supported by the National Natural Science Foundation of China(52203160,52362006,32360238)Project of Sanya Yazhou Bay Science and Technology City(SKJC-JYRC-2024-34,SKJC-JYRC-2024-33)Science and Technology Development Fund of Macao SAR(0002/2024/TFP,0139/2022/A3,0007/2021/AKP).
文摘Near-infrared(NIR)light-triggered pyroptosis based on biocompatible Pt(IV)-coordinated nanomedicine for tumor precision therapy is challenging.Here,we disclose a supramolecular approach to construct a hollow-spherical supra-(carbon dots)(HS-Pt-CDs)via ultrasound-assisted J-type assembly of Pt(IV)-coordinated carbon dots(Pt-CDs).The peculiar assembling behaviors arise from the steric hindrance and lattice distortion in the bowl-like Pt-CDs caused by the coordination of Pt(IV)atoms among the sp^(2)domains,which result in around 240 nm red-shifted absorption bands and promoting charge separation in the NIR region due to strong inter-molecular charge transfer(CT)in HS-Pt-CDs.The results reveal that HS-Pt-CDs exhibit excellent NIR light-activated photocatalytic capacities,involving the release of Pt(II)species,the generation of hydroxyl radicals,and acidification under 690 nm laser irradiation.Combined with the effective cellular uptake and tumor accumulation,HS-Pt-CDs can efficiently trigger cancer cell pyroptosis under 690 nm laser irradiation,resulting in the destruction of the primary tumor and effectively induction of strong immunogenic cell death(ICD),thereby evoking anti-tumor immune responses to suppress distant tumor and prevent cancer metastasis.Taken these merits,an important perspective of Pt(IV)-contained supra-CDs with outstanding NIRtriggered photocatalytic behaviors can be of great significance toward precision tumor phototherapy.
文摘The construction of modern cities emphasizes the nature and harmony among the“people”,“things”and“environment”,reflecting the harmony and unity of the formal beauty,functional beauty and surrounding environment of architecture.Based on the introduction of the design concept of the assembled pedestrian overbridge,through the Jianhua Building Materials Group’s first“pre-fabricated low-rise tower-stayed pedestrian landscape overbridge”project in China,this paper proposes a solution that can improve the landscape design of the overbridge and reduce the construction complexity of the overbridge,the assembly product supply and the construction process“integration”under the premise of ensuring the safety and stability of the pedestrian overbridge,whose prefabricated production and assembly construction,shortening the construction period,reducing energy consumption,reducing pollution,and obtaining good social comprehensive benefits.
基金The authors are grateful for the financial support received from the National Key R&D Program(2017YFF0205003)Hebei Province Higher Education Science and Technology Research Project(ZD2018249)Special funded by the Beijing Institute of Housing and Urban-Rural Science and Technology.
文摘Analyze and compare the basic principles of ultrasonic detection of voids in concrete,choose ZBL-U520/510 non-metallic ultrasonic detector,and use the opposite detection method to test the void size in the joints of prefabri-cated concrete structures.The results show that:ultrasonic method by testing the waveform,sound,and speed of sound analysis can effectively determine the position of the defect,and through the conversion formula can estimate the void size.Ultrasonic parameters are used to distinguish the internal defects of Assembly concrete.Sometimes there are diferent results with different para-meters.It is difficult for engineers to directly determine the internal de fects.Fuzzy comprehensive ev aluation can establish an overall evaluation of things or objects controlled by multiple factors by establishing membership functions.Through the inspection of engineering examples:the fuzzy comprehensive judgment method has no difference between the judgment of some good quality points and the judg-ment results of the original criteria,but for some abnormal points or points near the critical value,the advantages of fiuzzy criteria can be achieved.The judgment process will be more scientific by considering several parameters in a comprehen-sive manner and digtizing the original subjective judgments.
文摘An assembly type flowshop scheduling problem with minimizing makespan is considered in this paper. The problem of scheduling for minimizing makespan is first addressed, and then a new heuristic algorithm is proposed for it.
文摘With the improvement of Chinas urban construction level, the scale of the construction industry is constantly expanding, and the traditional production methods, production techniques and production technologies can no longer adapt to the development of cities. With the continuous development and application of building technology, prefabricated building components and BIM technology, the idea of green, low-carbon, environmental protection and sustainable development has become an inevitable choice to promote the transformation and upgrading of the construction industry. Relevant departments of the state, provinces and cities have issued a series of policies, which have promoted the research and development and engineering practice of prefabricated concrete construction technology, and promoted the application of BIM technology in the whole construction process. Therefore, the application of BIM technology in precast concrete structures has become a research hotspot, combining the two will bring greater economic and social benefits.
文摘China's continuous economic progress, the deepening process of urbanization, and the gradual improvement of people's living standards have brought more opportunities for the development of the construction industry. The number of construction projects is increasing, and the scale of projects is expanding. In order to meet the increasing demand of people for the number of buildings, the construction industry is developing and innovating, and the application of prefabricated building mode comes into being. Building curtain wall is an important part of prefabricated building. Glass curtain wall is widely used in practice. In order to improve the overall quality of prefabricated building engineering and the overall beauty of the building, we should attach great importance to the construction of prefabricated building curtain wall and adopt scientific curtain wall construction technology. Combined with the concept of prefabricated building, this paper deeply analyzes the key points of curtain wall construction technology and the specific application of curtain wall construction method of prefabricated building, which provides valuable reference experience for building a scientific and complete curtain wall construction technology system of prefabricated building, providing technical support for prefabricated building, and promoting the healthy and sustainable development of prefabricated building in China.
文摘Nowadays, the prefabrication level of bridge engineering is higher and higher, and many prefabricated components are used in construction, such as prefabricated bent cap. Compared with the previous cap beam construction technology, the fabricated cap beam can not only ensure the construction quality, but also speed up the construction speed, shorten the construction period, and lay a good foundation for bridge construction. Combined with the construction practice, this paper studies and discusses the important links of prefabricated bridge construction, the installation technology of precast column and the key points of construction quality control, hoping to provide reference for the compilation of relevant construction specifications in the future.
文摘Prefabricated buildings are the focus of attention and research in Chinas construction field and related industries. Compared with conventional brick-concrete buildings, such buildings have the advantages of less pollution, less construction waste and simplified manual operation. However, the main reason for restricting the popularization and use of prefabricated buildings in the market is that the design experience of such buildings is less, that is, the design results often have the problem of node collision during the on-site assembly construction, which not only affects the overall design quality of the building, but also interferes with the subsequent assembly construction of the project. Therefore, it is necessary to comprehensively deepen the design of prefabricated building structure on the basis of existing working technology and information technology.
文摘With the progress of science and technology, China's industrial development is gradually in the leading position in the world, the country also gradually uses steel structure buildings in the field of construction, and according to the actual situation and people's needs, constantly improve the design and construction, adhere to the road of sustainable development.
