We report a one-pot three-component synthesis of N-arylmethyl-4-(7-cyclohepta-1,3,5-trienyl)anilines by using various aromatic imines, tropylium tetrafluoroborate, and sodium tetrahydroborate in the presence of imidaz...We report a one-pot three-component synthesis of N-arylmethyl-4-(7-cyclohepta-1,3,5-trienyl)anilines by using various aromatic imines, tropylium tetrafluoroborate, and sodium tetrahydroborate in the presence of imidazole as activator.展开更多
A highly selective synthesis of 2-aryl-l-arylmethyl-lH-1,3-benzimidazoles from the reaction of o-phenylene- diamine and aromatic aldehydes in the presence of silica-bonded propyl-S-sulfonic acid （SBSSA） at 80℃ in w...A highly selective synthesis of 2-aryl-l-arylmethyl-lH-1,3-benzimidazoles from the reaction of o-phenylene- diamine and aromatic aldehydes in the presence of silica-bonded propyl-S-sulfonic acid （SBSSA） at 80℃ in water in good to excellent yields was developed.展开更多
An efficient method has been developed for one-pot three-component coupling reactions of various aldehydes, 1-cyclohexen-2-one, and primary or secondary amines in the presence of a catalytic amount of Yb（OTf）3 under...An efficient method has been developed for one-pot three-component coupling reactions of various aldehydes, 1-cyclohexen-2-one, and primary or secondary amines in the presence of a catalytic amount of Yb（OTf）3 under mild conditions to afford the corresponding 2-arylmethyl N-substituted anilines in good yields. In addition, the catalyst was easily recovered and could be reused for at least four cycles without any loss of activity.展开更多
Photolysis of benzyl phenylacetate (ACO_2A), benzyl p-methylphenylacetate (BCO_2A) and 1-naphthyl phenylacetate (ACO_2Np) in homogeneous and micellar solutions results in products typical of radical coupling reactions...Photolysis of benzyl phenylacetate (ACO_2A), benzyl p-methylphenylacetate (BCO_2A) and 1-naphthyl phenylacetate (ACO_2Np) in homogeneous and micellar solutions results in products typical of radical coupling reactions and loss of carbon dioxide. The cage effects upon direct photolysis of these esters in acetonitrile are significantly greater than zero and those in SDS or HDTBr micellar solutions are even greater. In the triplet sensitization reaction of ACO_2 Np in micellar solutions the cage effects are smaller than those obtained upon direct irradiation. However, the application of a 0.05 or 0.2 T external magnetic field in the photolysis in micellar solutions decreases the cage effects dramatically. All these results suggest that the photoextrusions of carbon dioxide from these esters proceed via radical intermediates, and upon direct photolysis the reactive states for the cleavage re- action involve both singlet and triplet excited states.展开更多
Chiral ligand (R)-N, N'-Bis(2-hydroxy-3,5-di- tert-butyl-aryl-methyl)-1, 1'-binaphthalene-2,2'-diamine derived from the reduction of Schiff base (R)-2,2'-bis (3,5-di-tert-butyl-2-hy-droxybenzylideneami...Chiral ligand (R)-N, N'-Bis(2-hydroxy-3,5-di- tert-butyl-aryl-methyl)-1, 1'-binaphthalene-2,2'-diamine derived from the reduction of Schiff base (R)-2,2'-bis (3,5-di-tert-butyl-2-hy-droxybenzylideneamino)-1, 1'-binaphthyl with LiAIH(4) is fairly effective in the asymmetric addition reaction of diethylzinc to aldehydes by which good yields (46%-94%) of the corresponding sec-alcohols can be obtained in moderate ee (51%-79%) with R configuration for a variety of aldehydes.展开更多
Glyoxylic acid （5 mol%） performs as a novel highly water-soluble catalyst for the synthesis of 2-aryl-l-arylmethyl-lH- benzimidazoles from a wide range of substituted o-phenylenediamines and various substituted alde...Glyoxylic acid （5 mol%） performs as a novel highly water-soluble catalyst for the synthesis of 2-aryl-l-arylmethyl-lH- benzimidazoles from a wide range of substituted o-phenylenediamines and various substituted aldehydes in good to excellent isolated yields （85-95%） using water as solvent at ambient temperature. The remarkable advantages offered by this method are easily and inexpensive available catalyst, simple procedure, mild conditions, much faster （20--40 rain） reactions and excellent yields of products.展开更多
文摘We report a one-pot three-component synthesis of N-arylmethyl-4-(7-cyclohepta-1,3,5-trienyl)anilines by using various aromatic imines, tropylium tetrafluoroborate, and sodium tetrahydroborate in the presence of imidazole as activator.
文摘A highly selective synthesis of 2-aryl-l-arylmethyl-lH-1,3-benzimidazoles from the reaction of o-phenylene- diamine and aromatic aldehydes in the presence of silica-bonded propyl-S-sulfonic acid （SBSSA） at 80℃ in water in good to excellent yields was developed.
基金Project supported by the National Natural Science Foundation of China （No. 20672035） and Key Laboratory of 0rganofluorine Chemistry, Shanghai Institute of 0rganic Chemistry, Chinese Academy of Sciences.
文摘An efficient method has been developed for one-pot three-component coupling reactions of various aldehydes, 1-cyclohexen-2-one, and primary or secondary amines in the presence of a catalytic amount of Yb（OTf）3 under mild conditions to afford the corresponding 2-arylmethyl N-substituted anilines in good yields. In addition, the catalyst was easily recovered and could be reused for at least four cycles without any loss of activity.
基金This work was supported by the National Science Foundation of China and the National Laboratory for Structure Chemistry of Unstable and Stable Species
文摘Photolysis of benzyl phenylacetate (ACO_2A), benzyl p-methylphenylacetate (BCO_2A) and 1-naphthyl phenylacetate (ACO_2Np) in homogeneous and micellar solutions results in products typical of radical coupling reactions and loss of carbon dioxide. The cage effects upon direct photolysis of these esters in acetonitrile are significantly greater than zero and those in SDS or HDTBr micellar solutions are even greater. In the triplet sensitization reaction of ACO_2 Np in micellar solutions the cage effects are smaller than those obtained upon direct irradiation. However, the application of a 0.05 or 0.2 T external magnetic field in the photolysis in micellar solutions decreases the cage effects dramatically. All these results suggest that the photoextrusions of carbon dioxide from these esters proceed via radical intermediates, and upon direct photolysis the reactive states for the cleavage re- action involve both singlet and triplet excited states.
基金theMajorStateBasicResearchDevelopmentProgram (No .G2 0 0 0 0 480 0 7)andtheNationalNaturalScienceFoundationofChina (No .2 0 0 2 5 2 0 6 )
文摘Chiral ligand (R)-N, N'-Bis(2-hydroxy-3,5-di- tert-butyl-aryl-methyl)-1, 1'-binaphthalene-2,2'-diamine derived from the reduction of Schiff base (R)-2,2'-bis (3,5-di-tert-butyl-2-hy-droxybenzylideneamino)-1, 1'-binaphthyl with LiAIH(4) is fairly effective in the asymmetric addition reaction of diethylzinc to aldehydes by which good yields (46%-94%) of the corresponding sec-alcohols can be obtained in moderate ee (51%-79%) with R configuration for a variety of aldehydes.
基金Head,Department of Chemistry,Vinayakrao Patil Mahavidyala Vaijapur 423701(M.S.),India,for partial support of this work.
文摘Glyoxylic acid （5 mol%） performs as a novel highly water-soluble catalyst for the synthesis of 2-aryl-l-arylmethyl-lH- benzimidazoles from a wide range of substituted o-phenylenediamines and various substituted aldehydes in good to excellent isolated yields （85-95%） using water as solvent at ambient temperature. The remarkable advantages offered by this method are easily and inexpensive available catalyst, simple procedure, mild conditions, much faster （20--40 rain） reactions and excellent yields of products.
