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Noninvasive interception of circulating leukocyte in vivo by optical tweezer array 被引量:1
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作者 Sisi Ge Jinhua Zhou Xunbin Wei 《Journal of Innovative Optical Health Sciences》 2026年第1期56-69,共14页
The ability to noninvasively manipulate and isolate specific cell populations in vivo is critical for advancing real-time diagnostics,precision medicine,and immunological research.Here,we present a novel and broadly a... The ability to noninvasively manipulate and isolate specific cell populations in vivo is critical for advancing real-time diagnostics,precision medicine,and immunological research.Here,we present a novel and broadly applicable optical trapping system based on a custom-designed 2×3 optical tweezer array,which enables the real-time interception and manipulation of circulating leukocytes in live animals.By utilizing intrinsic velocity differences between leukocytes and red blood cells,the system achieves stable trapping of individual leukocytes in vessels 15-20μm in diameter and decelerates multiple cells in vessels greater than 20μm.Notably,it also enables the optical blockage of lymphatic vessels exceeding 50μm,a previously unreported capability.This label-free,noninvasive approach operates without repeated blood draws and is compatible with diverse vessel geometries and flow dynamics.The system offers a generalizable solution for in vivo cell extraction and analysis,paving the way for high-precision single-cell technologies in biomedical research and clinical translation. 展开更多
关键词 Leukocytes optical tweezer array in vivo interception
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A new 10K liquid SNP genotyping array for wax gourd and its application in heterosis utilization and cultivars identification
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作者 Dan Liu Lingling Xie +4 位作者 Yuting Lei Bingchuan Tian Daolong Liao Fangfang Wu Baobin Mi 《Journal of Integrative Agriculture》 2026年第2期734-743,共10页
High-throughput single nucleotide polymorphism(SNP) arrays have emerged as essential genotyping tools,significantly accelerating breeding programs and advancing basic research.In this study,a high-throughput 10K SNP g... High-throughput single nucleotide polymorphism(SNP) arrays have emerged as essential genotyping tools,significantly accelerating breeding programs and advancing basic research.In this study,a high-throughput 10K SNP genotyping array for wax gourd was developed using genotyping by target sequencing(GBTS),featuring 10,722 SNPs evenly distributed across all 12 chromosomes,including 278 functional loci associated with key economic traits.To demonstrate its utility,genetic distances among 19 elite inbred lines were calculated from SNP data and correlated with heterosis for single fruit weight.The results revealed that greater genetic distance was associated with higher middle parent heterosis(MPH) for single fruit weight.Furthermore,56 commercial wax gourd cultivars collected from eight regions were selected and genotyped.Population structure analysis,phylogenetic analysis,and principal component analysis(PCA) collectively indicated that these cultivars fall into two major groups.Group I,comprising black or dark green skinned wax gourds,exhibited lower genetic diversity than Group II,which includes green or light green skinned varieties,reflecting shorter genetic distances within Group I.Finally,60 polymorphic SNPs were used to construct DNA fingerprints for distinguishing the 56 cultivars.As the first high-throughput genotyping platform for wax gourd,this SNP array provides an effective and powerful tool for genetic analysis. 展开更多
关键词 wax gourd SNP genotyping array HETEROSIS cultivar identification DNA fingerprint
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A Reconfigurable Omnidirectional Triboelectric Whisker Sensor Array for Versatile Human–Machine–Environment Interaction
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作者 Weichen Wang Jiaqi Zhu +9 位作者 Hongfa Zhao Fei Yao Yuzhu Zhang Xiankuan Qian Mingrui Shu Zhigang Wu Minyi Xu Hongya Geng Wenbo Ding Juntian Qu 《Nano-Micro Letters》 2026年第3期121-140,共20页
Developing effective,versatile,and high-precision sensing interfaces remains a crucial challenge in human-machine-environment interaction applications.Despite progress in interaction-oriented sensing skins,limitations... Developing effective,versatile,and high-precision sensing interfaces remains a crucial challenge in human-machine-environment interaction applications.Despite progress in interaction-oriented sensing skins,limitations remain in unit-level reconfiguration,multiaxial force and motion sensing,and robust operation across dynamically changing or irregular surfaces.Herein,we develop a reconfigurable omnidirectional triboelectric whisker sensor array(RO-TWSA)comprising multiple sensing units that integrate a triboelectric whisker structure(TWS)with an untethered hydro-sealing vacuum sucker(UHSVS),enabling reversibly portable deployment and omnidirectional perception across diverse surfaces.Using a simple dual-triangular electrode layout paired with MXene/silicone nanocomposite dielectric layer,the sensor unit achieves precise omnidirectional force and motion sensing with a detection threshold as low as 0.024 N and an angular resolution of 5°,while the UHSVS provides reliable and reversible multi-surface anchoring for the sensor units by involving a newly designed hydrogel combining high mechanical robustness and superior water absorption.Extensive experiments demonstrate the effectiveness of RO-TWSA across various interactive scenarios,including teleoperation,tactile diagnostics,and robotic autonomous exploration.Overall,RO-TWSA presents a versatile and high-resolution tactile interface,offering new avenues for intelligent perception and interaction in complex real-world environments. 展开更多
关键词 Reconfigurable sensor array Interaction interface Tactile perception Omnidirectional sensor Reversible anchoring
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重症感染患者血清lncRNA UCA1、miR-331-3p与病情严重程度及预后的相关性
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作者 刘芳 周诗乾 +2 位作者 罗必成 刘佳 刘立志 《创伤与急危重病医学》 2026年第1期31-35,40,共6页
目的探讨重症感染患者血清lncRNA UCA1、miR-331-3p与病情严重程度及预后的相关性。方法选取2023年1月至2024年1月湖北省监利市人民医院收治的84例重症感染患者,男性39例,女性45例,年龄(49.8±8.1)岁,年龄范围为43~59岁。根据重症... 目的探讨重症感染患者血清lncRNA UCA1、miR-331-3p与病情严重程度及预后的相关性。方法选取2023年1月至2024年1月湖北省监利市人民医院收治的84例重症感染患者,男性39例,女性45例,年龄(49.8±8.1)岁,年龄范围为43~59岁。根据重症感染程度将患者分为脓毒症组(n=47)及感染休克组(n=37)。另选取同期于湖北省监利市人民医院体检的40名健康者作为健康组,男性19例,女性21例,年龄(51.0±8.7)岁,年龄范围为42~60岁。收集所有纳入者的一般资料(年龄、性别、体质量指数、合并症、感染部位)及临床资料[C反应蛋白(CPR)、白细胞计数、血小板计数、急性生理学和慢性健康状况评价Ⅱ(APACHEⅡ)评分],记录重症感染患者1个月后的生存情况作为预后。检测纳入者血清lncRNA UCA1、miR-331-3p表达水平,预测血清lncRNA UCA1、miR-331-3p的相互作用关系,并进一步研究重症感染患者各指标与预后的关系。结果生物信息学预测发现,血清lncRNA UCA1与miR-331-3p存在靶向结合位点。1个月后,重症感染患者存活54例,病死30例。Logistic回归分析显示,APACHEII评分、lncRNA UCA1升高是患者预后的独立危险因素,miR-331-3p升高是患者预后的独立保护因素(P<0.05)。受试者操作特征曲线结果显示,血清lncRNA UCA1、miR-331-3p联合预测重症感染患者预后情况的曲线下面积高于血清lncRNA UCA1及miR-331-3p单独预测(P<0.05)。结论血清lncRNA UCA1、miR-331-3p表达水平可用于判断重症感染病情程度,二者联合的预测效果优于单独预测。 展开更多
关键词 重症感染 长链非编码RNA uca1 微小RNA-331-3p
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3D printed high-temperature ceramic conformal array antenna:Design,analysis,manufacturing,and testing
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作者 Peng Li Ruibo Li +5 位作者 Zijiao Fan Jiujiu Han Guangda Ding Qunbiao Wang Wanye Xu Paolo Rocca 《Defence Technology(防务技术)》 2026年第1期340-353,共14页
In this study,the design,analysis,manufacturing,and testing of a 3D-printed conformal microstrip array antenna for high-temperature environments is presented.3D printing technology is used to fabricate a curved cerami... In this study,the design,analysis,manufacturing,and testing of a 3D-printed conformal microstrip array antenna for high-temperature environments is presented.3D printing technology is used to fabricate a curved ceramic substrate,and laser sintering and microdroplet spraying processes are used to add the conductive metal on the curved substrate.The problems of gain loss,bandwidth reduction,and frequency shift caused by high temperatures are addressed by using a proper antenna design,with parasitic patches,slots,and metal resonant cavities.The antenna prototype is characterized by the curved substrates and the conductive metals for the power dividers,the patch,and the ground plane;its performance is examined up to a temperature of 600℃in a muffle furnace and compared with the results from the numerical analysis.The results show that the antenna can effectively function at 600℃and even higher temperatures. 展开更多
关键词 Ceramic antenna Conformal array High-temperature environment 3D printing High gain and wide band
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UCA1和ITGA2在胰腺癌中的作用及调控机制
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作者 卫丽娟 许建 《实用医院临床杂志》 2025年第5期210-214,共5页
胰腺癌是一种高度致死的恶性肿瘤。长链非编码RNA UCA1在多种癌症中均表现出较高的表达水平,特别是在胰腺癌中,通过MAPK/ERK等信号通路推动癌细胞的迁移与侵袭,因此被视为有潜力的预后标志物和治疗靶点。同时,整合素家族成员ITGA2的高... 胰腺癌是一种高度致死的恶性肿瘤。长链非编码RNA UCA1在多种癌症中均表现出较高的表达水平,特别是在胰腺癌中,通过MAPK/ERK等信号通路推动癌细胞的迁移与侵袭,因此被视为有潜力的预后标志物和治疗靶点。同时,整合素家族成员ITGA2的高表达也与胰腺癌细胞的侵袭性及转移能力密切相关,其通过黏着斑信号途径调控癌症进展。此外,UCA1和ITGA2之间可能通过miR-107作为中介,协同影响胰腺癌的恶性生物学行为,表明UCA1和ITGA2有望作为胰腺癌诊断和治疗的新靶点。本文综述了UCA1和ITGA2在胰腺癌中的功能及其调控机制,未来研究应深入探索它们在胰腺癌中的具体机制及潜在的临床应用前景。 展开更多
关键词 uca1 ITGA2 miR-107 胰腺癌
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Structural Color Dynamic Graphics Display Based on Microlens Array 被引量:1
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作者 LI Xue-han LIU Ling-zhi +1 位作者 HUANG Min LI Xiu 《印刷与数字媒体技术研究》 北大核心 2025年第2期162-168,共7页
It is of great scientific significance to construct a 3D dynamic structural color with a special color effect based on the microlens array.However,the problems of imperfect mechanisms and poor color quality need to be... It is of great scientific significance to construct a 3D dynamic structural color with a special color effect based on the microlens array.However,the problems of imperfect mechanisms and poor color quality need to be solved.A method of 3D structural color turning on periodic metasurfaces fabricated by the microlens array and self-assembly technology was proposed in this study.In the experiment,Polydimethylsiloxane(PDMS)flexible film was used as a substrate,and SiO2 microspheres were scraped into grooves of the PDMS film to form 3D photonic crystal structures.By adjusting the number of blade-coated times and microsphere concentrations,high-saturation structural color micropatterns were obtained.These films were then matched with microlens arrays to produce dynamic graphics with iridescent effects.The results showed that by blade-coated two times and SiO2 microsphere concentrations of 50%are the best conditions.This method demonstrates the potential for being widely applied in the anticounterfeiting printing and ultra-high-resolution display. 展开更多
关键词 Structural color Microlens array Dynamic graphics display Moirémagnification Optical anti-counterfeiting
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HBV相关肝细胞癌患者血清UCA1、WRAP53表达水平及其临床意义
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作者 杨斌 王勇刚 +1 位作者 曹洪刚 高建勇 《肝脏》 2025年第7期943-947,共5页
目的探究乙型肝炎病毒(HBV)相关肝细胞癌患者血清尿路上皮癌相关1(UCA1)和含TP53反义的WD重复序列(WRAP53)水平与肝癌的关系。方法选取2022年6月至2024年3月于乐至县人民医院肿瘤内科接受治疗的HBV相关肝细胞癌患者82例作为观察组,选择... 目的探究乙型肝炎病毒(HBV)相关肝细胞癌患者血清尿路上皮癌相关1(UCA1)和含TP53反义的WD重复序列(WRAP53)水平与肝癌的关系。方法选取2022年6月至2024年3月于乐至县人民医院肿瘤内科接受治疗的HBV相关肝细胞癌患者82例作为观察组,选择同期慢性HBV感染者80例作为对照组。实时荧光定量PCR测定患者血清UCA1和WRAP53水平,应用二元logistic回归模型分析慢性HBV感染者肝癌发生的危险因素。采用受试者工作特征(ROC)曲线及曲线下面积(AUC)评估UCA1和WRAP53对HBV相关肝细胞癌的诊断效能。结果观察组血清UCA1和WRAP53的表达水平分别为(2.42±0.72)和(3.16±1.07),高于对照组的(1.25±0.37)和(1.18±0.31),差异有统计学意义(t=13.054、16.079,均P<0.05)。Logistic回归分析表明,UCA1和WRAP53水平升高是慢性HBV感染者肝癌发生的独立危险因素。ROC曲线分析显示,UCA1和WRAP53诊断慢性HBV感染者肝癌发生的灵敏度分别为84.1%和90.2%;特异度分别为88.7%和96.3%;AUC分别为0.921和0.930,显示了两者在诊断慢性HBV感染者肝癌发生的高准确性。而当UCA1和WRAP53联合预测时,灵敏度和特异度分别为93.9%和98.8%,AUC值则达到0.980,表明联合检测具有更高的预测效能。结论HBV相关肝细胞癌患者的血清UCA1和WRAP53水平显著升高,这些标志物可作为HBV相关肝细胞癌的潜在诊断工具,具有较高的诊断价值。 展开更多
关键词 乙型肝炎病毒 肝细胞癌 uca1 WRAP53 生物标志物
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Improving DOA estimation of GNSS interference through sparse non-uniform array reconfiguration 被引量:3
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作者 Rongling LANG Hao XU +3 位作者 Fei GAO Zewen TANG Zhipeng WANG Amir HUSSAIN 《Chinese Journal of Aeronautics》 2025年第8期104-118,共15页
Interference significantly impacts the performance of the Global Navigation Satellite Systems(GNSS),highlighting the need for advanced interference localization technology to bolster anti-interference and defense capa... Interference significantly impacts the performance of the Global Navigation Satellite Systems(GNSS),highlighting the need for advanced interference localization technology to bolster anti-interference and defense capabilities.The Uniform Circular Array(UCA)enables concurrent estimation of the Direction of Arrival(DOA)in both azimuth and elevation.Given the paramount importance of stability and real-time performance in interference localization,this work proposes an innovative approach to reduce the complexity and increase the robustness of the DOA estimation.The proposed method reduces computational complexity by selecting a reduced number of array elements to reconstruct a non-uniform sparse array from a UCA.To ensure DOA estimation accuracy,minimizing the Cramér-Rao Bound(CRB)is the objective,and the Spatial Correlation Coefficient(SCC)is incorporated as a constraint to mitigate side-lobe.The optimization model is a quadratic fractional model,which is solved by Semi-Definite Relaxation(SDR).When the array has perturbations,the mathematical expressions for CRB and SCC are re-derived to enhance the robustness of the reconstructed array.Simulation and hardware experiments validate the effectiveness of the proposed method in estimating interference DOA,showing high robustness and reductions in hardware and computational costs associated with DOA estimation. 展开更多
关键词 GNSS interference location Direction of arrival estimation Adaptive reconfigurable array Cramér-Raobound Quadratic fractional programming
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lncRNA UCA1在口腔鳞状细胞癌中的研究进展 被引量:1
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作者 陈玥 孙雪倩 陈敏敏 《口腔医学》 2025年第4期317-320,共4页
口腔鳞状细胞癌(oral squamous cell carcinoma,OSCC)是最高发的头颈部恶性肿瘤,其发病率和死亡率仍然较高。长链非编码RNA(long non-coding RNA,lncRNA)是一类重要的非编码RNA分子,在OSCC的发生和发展中发挥着重要作用。尿路上皮癌抗原... 口腔鳞状细胞癌(oral squamous cell carcinoma,OSCC)是最高发的头颈部恶性肿瘤,其发病率和死亡率仍然较高。长链非编码RNA(long non-coding RNA,lncRNA)是一类重要的非编码RNA分子,在OSCC的发生和发展中发挥着重要作用。尿路上皮癌抗原1(urothelial carcinoma associated 1,UCA1)在OSCC中高水平表达,通过miRNA的海绵作用以及激活下游信号通路调节肿瘤细胞的生物学行为。本文综述了UCA1在OSCC中的作用机制及其在肿瘤增殖、侵袭转移、耐药、诊断、治疗及预后等方面的研究进展,这有望为UCA1在OSCC的潜在临床应用提供理论基础。 展开更多
关键词 口腔鳞状细胞癌 lncRNA uca1 致癌作用 诊断和预后 肿瘤治疗
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Integrated Optical True Time Delay Phased Array Antenna Systems 被引量:1
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作者 Qi Zihang Yang Linhui +1 位作者 Zhao Wenyu Li Xiuping 《China Communications》 2025年第5期152-172,共21页
The integrated optical true time delay phased array antenna system has the advantages of high bandwidth,small size,low loss and strong antiinterference capability,etc.The high integration of the optically controlled p... The integrated optical true time delay phased array antenna system has the advantages of high bandwidth,small size,low loss and strong antiinterference capability,etc.The high integration of the optically controlled phased array antenna system is a necessary trend for the future development of the phased array,and it is also a major focus and difficulty in the current research of integrated microwave photonics.This paper firstly introduces the basic principle and development history of optical true time delay phased array antenna system based on microwave photonics,and briefly introduces the main implementation methods and integration platform of optical true time delay.Then,the application and development prospect of optical true time delay technology in beam control of phased array antenna system are mainly presented.Finally,according to the current research progress,the possible research directions of integrated optically controlled phased array antenna systems in the future are proposed. 展开更多
关键词 microwave photonics optical switch optical true time delay phased array antenna siliconbased integration
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Low-profile,low sidelobe array antenna with ultrawide beam coverage for UAV communication 被引量:1
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作者 Mei LI Zhiliang SHANG +2 位作者 Lin PU Ming-Chun TANG Lei ZHU 《Chinese Journal of Aeronautics》 2025年第1期444-454,共11页
This paper presents a design method to implement an antenna array characterized by ultra-wide beam coverage,low profile,and low Sidelobe Level(SLL)for the application of Unmanned Aerial Vehicle(UAV)air-to-ground commu... This paper presents a design method to implement an antenna array characterized by ultra-wide beam coverage,low profile,and low Sidelobe Level(SLL)for the application of Unmanned Aerial Vehicle(UAV)air-to-ground communication.The array consists of ten broadside-radiating,ultrawide-beamwidth elements that are cascaded by a central-symmetry series-fed network with tapered currents following Dolph-Chebyshev distribution to provide low SLL.First,an innovative design of end-fire Huygens source antenna that is compatible with metal ground is presented.A low-profile,half-mode Microstrip Patch Antenna(MPA)is utilized to serve as the magnetic dipole and a monopole is utilized to serves as the electric dipole,constructing the compact,end-fire,grounded Huygens source antenna.Then,two opposite-oriented end-fire Huygens source antennas are seamlessly integrated into a single antenna element in the form of monopole-loaded MPA to accomplish the ultrawide,broadside-radiating beam.Particular consideration has been applied into the design of series-fed network as well as antenna element to compensate the adverse coupling effects between elements on the radiation performance.Experiment indicates an ultrawide Half-Power Beamwidth(HPBW)of 161°and a low SLL of-25 dB with a high gain of 12 d Bi under a single-layer configuration.The concurrent ultrawide beamwidth and low SLL make it particularly attractive for applications of UAV air-to-ground communication. 展开更多
关键词 array antenna Broad beam Fan beam Low sidelobe level Chebyshev synthesis UAV communication
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Arbitrary azimuthal optical field manipulation by dual-spiral arrays
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作者 MA Li WANG Ying +2 位作者 LI Min ZHANG Ying ZHAO Bo 《中国光学(中英文)》 北大核心 2025年第4期921-930,共10页
Optical field manipulation,an emerging frontier in photonics,demonstrates significant potential in biomedical microscopy,quantum state engineering,and micro-nano fabrication.To address the critical limitations of curr... Optical field manipulation,an emerging frontier in photonics,demonstrates significant potential in biomedical microscopy,quantum state engineering,and micro-nano fabrication.To address the critical limitations of current optical modulation technologies in achieving full-parameter precision control,we proposed a novel approach for dynamic azimuthal optical field modulation based on dual-spiral arrays.By designing spatially interleaved spiral structures with different initial radii while maintaining identical periodic parameters,we achieved continuous optical modulation spanning the full 0-2πrange in azimuthal field distribution.Through rigorous numerical simulations,we systematically established a quantitative correlation between the structural parameters and azimuthal optical field patterns,revealing,for the first time,a quasi-linear relationship between the radius difference and the resultant optical distribution.This theoretical framework advances our fundamental understanding of structured optical field manipulation as well as provides a new paradigm for programmable photonic device design,with distinct technical advantages in super-resolution imaging and optical tweezer systems. 展开更多
关键词 optical manipulation topological charge spiral array
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Earthquake monitoring and high-resolution velocity tomography for the central Longmenshan fault zone by a temporary dense seismic array 被引量:1
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作者 ShaoBo Yang HaiJiang Zhang +4 位作者 MaoMao Wang Ji Gao Shuaijun Wang BaoJin Liu XiWei Xu 《Earth and Planetary Physics》 2025年第2期239-252,共14页
The Longmenshan(LMS)fault zone is located at the junction of the eastern Tibetan Plateau and the Sichuan Basin and is of great significance for studying regional tectonics and earthquake hazards.Although regional velo... The Longmenshan(LMS)fault zone is located at the junction of the eastern Tibetan Plateau and the Sichuan Basin and is of great significance for studying regional tectonics and earthquake hazards.Although regional velocity models are available for the LMS fault zone,high-resolution velocity models are lacking.Therefore,a dense array of 240 short-period seismometers was deployed around the central segment of the LMS fault zone for approximately 30 days to monitor earthquakes and characterize fine structures of the fault zone.Considering the large quantity of observed seismic data,the data processing workflow consisted of deep learning-based automatic earthquake detection,phase arrival picking,and association.Compared with the earthquake catalog released by the China Earthquake Administration,many more earthquakes were detected by the dense array.Double-difference seismic tomography was adopted to determine V_(p),V_(s),and V_(p)/V_(s)models as well as earthquake locations.The checkerboard test showed that the velocity models have spatial resolutions of approximately 5 km in the horizontal directions and 2 km at depth.To the west of the Yingxiu–Beichuan Fault(YBF),the Precambrian Pengguan complex,where most of earthquakes occurred,is characterized by high velocity and low V_(p)/V_(s)values.In comparison,to the east of the YBF,the Upper Paleozoic to Jurassic sediments,where few earthquakes occurred,show low velocity and high V_(p)/V_(s)values.Our results suggest that the earthquake activity in the LMS fault zone is controlled by the strength of the rock compositions.When the high-resolution velocity models were combined with the relocated earthquakes,we were also able to delineate the fault geometry for different faults in the LMS fault zone. 展开更多
关键词 Longmenshan fault zone dense seismic array deep learning double-difference seismic tomography seismic velocity model earthquake locations fault geometry
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Ultrafast Self-powered Near-infrared Photodetectors and Imaging Array Based on Tin-lead Mixed Perovskites
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作者 LIU Jingjing YANG Zhichun +7 位作者 BAO Haotian MENG Xinqin QI Minru YANG Changgang ZHANG Guofeng QIN Chengbing XIAO Liantuan JIA Suotang 《发光学报》 北大核心 2025年第6期1037-1047,共11页
Tin-lead(Sn-Pb)mixed perovskites are extensively investigated in near-infrared(NIR)photodetectors(PDs)owing to their excellent photoelectric performance.However,achieving high-performance Sn-Pb mixed PDs remains chall... Tin-lead(Sn-Pb)mixed perovskites are extensively investigated in near-infrared(NIR)photodetectors(PDs)owing to their excellent photoelectric performance.However,achieving high-performance Sn-Pb mixed PDs remains challenging,primarily because of the rapid crystallization and the susceptibility of Sn^(2+) to oxidation.To ad⁃dress these issues,this study introduces the multifunctional molecules 2,3-difluorobenzenamine(DBM)to modulate the crystallization of Sn-Pb mixed perovskites and retard the oxidation of Sn^(2+),thereby significantly enhancing film quality.Compared with the pristine film,Sn-Pb mixed perovskite films modulated by DBM molecules exhibit a high⁃ly homogeneous morphology,reduced roughness and defect density.The self-powered NIR PDs fabricated with the improved films have a spectral response range from 300 nm to 1100 nm,a peak responsivity of 0.51 A·W^(-1),a spe⁃cific detectivity as high as 2.46×10^(11)Jones within the NIR region(780 nm to 1100 nm),a linear dynamic range ex⁃ceeding 152 dB,and ultrafast rise/fall time of 123/464 ns.Thanks to the outstanding performance of PDs,the fabri⁃cated 5×5 PDs array demonstrates superior imaging ability in the NIR region up to 980 nm.This work advances the development of Sn-Pb mixed perovskites for NIR detection and paves the way for their commercialization. 展开更多
关键词 tin-lead mixed perovskites near-infrared photodetectors imaging array oxidation crystallization modulation
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Retraction: UCA1 Regulates the Growth and Metastasis of Pancreatic Cancer by Sponging miR-135a
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作者 Oncology Research Editorial Office 《Oncology Research》 2025年第9期2596-2596,共1页
The published article titled“UCA1 Regulates the Growth and Metastasis of Pancreatic Cancer by Sponging miR-135a”has been retracted from Oncology Research,Vol.25,No.9,2017,pp.1529–1541.DOI:10.3727/096504017X14888987... The published article titled“UCA1 Regulates the Growth and Metastasis of Pancreatic Cancer by Sponging miR-135a”has been retracted from Oncology Research,Vol.25,No.9,2017,pp.1529–1541.DOI:10.3727/096504017X14888987683152 URL:https://www.techscience.com/or/v25n9/56938 Following the publication,concerns have been raised about a number of figures in this article.An unexpected area of similarity was identified in terms of the cellular data,where the results from differently performed experiments were intended to have been shown,although the areas immediately surrounding this area featured comparatively different distributions of cells. 展开更多
关键词 cellular datawhere pancreatic cancer cellular data similarity uca MIR RETRACTION
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Programmable array antenna based on nematic liquid crystals for the Ka-band
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作者 WANG Qiang KE Junchen BAI Lin 《Journal of Southeast University(English Edition)》 2025年第1期78-83,共6页
A programmable low-profile array antenna based on nematic liquid crystals(NLCs)is proposed.Each antenna unit comprises a square patch radiating structure and a tunable NLC-based phase shifter capable of achieving a ph... A programmable low-profile array antenna based on nematic liquid crystals(NLCs)is proposed.Each antenna unit comprises a square patch radiating structure and a tunable NLC-based phase shifter capable of achieving a phase shift exceeding 360°with high linearity.First,the above 64 antenna units are periodically arranged into an 8×8 NLC-based antenna array,and the bias voltage of the NLC-based phase shifter loaded on the antenna unit is adjusted through the control of the field-programmable gate array(FPGA)programming sequences.This configuration enables precise phase changes for all 64 channels.Numerical simulation,sample processing,and experimental measurements of the antenna array are conducted to validate the performance of the antenna.The numerical and experimental results demonstrate that the proposed antenna performs well within the frequency range of 19.5-20.5 GHz,with a 3 dB relative bandwidth of 10%and a maximum main lobe gain of 14.1 dBi.A maximum scanning angle of±34°is achieved through the adjustment of the FPGA programming sequence.This NLC-based programmable array antenna shows promising potential for applications in satellite communication. 展开更多
关键词 array antenna nematic liquid crystals electronically beam scanning field programmable gate array(FPGA)
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Investigation on the Influence of Mooring System Configuration on the Hydrodynamic Performance of an Oscillating Water Column Array System
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作者 XU Sheng JU Kun +2 位作者 JI Chun-yan DAI Sai-shuai YUAN Zhi-ming 《China Ocean Engineering》 2025年第6期1054-1069,共16页
This paper presents a multi-module oscillating water column(OWC)wave energy converter(WEC)array system,comprising seven interconnected OWC modules.The modules are connected by elastic ropes with clumped weights positi... This paper presents a multi-module oscillating water column(OWC)wave energy converter(WEC)array system,comprising seven interconnected OWC modules.The modules are connected by elastic ropes with clumped weights positioned at the ropes'midpoints.Three distinct mooring systems are designed for this OWC array,and the impact of mooring configurations on the hydrodynamic responses of the OWCs and mooring tensions is thoroughly examined.Three-dimensional potential flow theory is applied to perform time domain analyses.The motion responses of representative modules,the tension of specific mooring lines,and the spacing between adjacent modules in the array system are investigated through a comprehensive coupled dynamic analysis in the time domain.Based on these analyses,recommendations are provided for the optimal mooring system configuration for the array system. 展开更多
关键词 OWC array system mooring system hydrodynamic performance
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lncRNA UCA1调控miR-135b-5p对子痫前期滋养细胞增殖和侵袭的影响
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作者 谢依欣 李小倩 张志慧 《中国优生与遗传杂志》 2025年第5期1062-1068,共7页
目的探讨长链非编码RNA尿路上皮癌胚抗原1(lncRNA UCA1)靶向微小RNA-135b-5p(miR-135b-5p)对子痫前期(PE)滋养细胞增殖和侵袭的影响。方法:利用HTR-8/SVneo细胞构建体外PE模型,并检测细胞中lncRNA UCA1和miR-135b-5p的表达量。将构建PE... 目的探讨长链非编码RNA尿路上皮癌胚抗原1(lncRNA UCA1)靶向微小RNA-135b-5p(miR-135b-5p)对子痫前期(PE)滋养细胞增殖和侵袭的影响。方法:利用HTR-8/SVneo细胞构建体外PE模型,并检测细胞中lncRNA UCA1和miR-135b-5p的表达量。将构建PE模型的HTR-8/SVneo细胞分为NC组、sh-NC组、sh-lncRNA UCA1组、sh-lncRNA UCA1+anti-miR-NC组、sh-lncRNA UCA1+anti-miR-135b-5p组。通过克隆形成实验和EdU染色检测各组细胞增殖能力;Transwell实验检测各组细胞侵袭能力;qRT-PCR实验检测各组细胞中lncRNA UCA1、miR-135b-5p以及细胞增殖、侵袭相关基因的表达量;Western blot实验检测细胞增殖和侵袭相关蛋白的表达量;双荧光素酶报告基因实验检测lncRNA UCA1和miR-135b-5p靶向关系。结果与Control组相比,Sham组lncRNA UCA1表达量上升(P<0.05),miR-135b-5p表达量下降(P<0.05);与sh-NC组相比,sh-lncRNA UCA1组细胞增殖能力、侵袭能力、lncRNA UCA1、增殖细胞核抗原(PCNA)、周期蛋白依赖性激酶(CDK1)、基质金属蛋白酶(MMP)2、MMP14 mRNA表达量和蛋白表达量都明显下降(P<0.05),miR-135b-5p表达量明显上升(P<0.05);而上述指标变化趋势在sh-lncRNA UCA1+anti-miR-135b-5p组中均被逆转(P<0.05)。结论干扰lncRNA UCA1表达可通过靶向上调miR-135b-5p表达抑制PE滋养细胞增殖和侵袭。 展开更多
关键词 lncRNA uca1 miR-135b-5p 子痫前期 增殖 侵袭
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