BACKGROUND Colon polyps represent a significant clinical challenge in elderly patients.While endoscopic mucosal resection(EMR)and argon plasma coagulation(APC)are widely used,their comparative effectiveness in elderly...BACKGROUND Colon polyps represent a significant clinical challenge in elderly patients.While endoscopic mucosal resection(EMR)and argon plasma coagulation(APC)are widely used,their comparative effectiveness in elderly populations remains unclear,particularly regarding postoperative recovery and complication profiles.AIM To compare the postoperative recovery,complications and efficacy of EMR and APC in elderly patients with colonic polyps.METHODS We retrospectively analyzed clinical data from 224 elderly patients with colon polyps treated at our center between January 2021 and July 2024.All patients were divided into the EMR group and APC group according to the surgical method they received.By comparing the operation time,intraoperative bleeding situation,hospital stays,postoperative inflammatory response index,complication rate and recurrence status of the two groups,the effect of the two surgical methods was comprehensively evaluated.RESULTS The APC group exhibited superior outcomes in terms of operative time(10.63 minutes vs 13.27 minutes,P<0.001),intraoperative bleeding situation(39.00%vs 52.42%,P=0.031),and length of hospital stay(1.63 days vs 3.87 days,P<0.001)compared to the EMR group.The one-time resection rate of the APC group(94.69%)was higher than that of the EMR group(89.14%)(P=0.026).The overall effective rates of the two groups were 94.35%and 92.00%,respectively.Postoperative procalcitonin and C-reactive protein levels were lower in the APC group than in the EMR group(P<0.001).The incidence of complications was comparable between the two groups(P=0.159).The recurrence rate was lower in the APC group(2.00%)than in the EMR group(8.06%)(P=0.045).CONCLUSION For elderly patients with colon polyps,APC showed certain advantages compared with EMR in promoting postoperative recovery,reducing the inflammatory response and the risk of complications.However,the study is limited by its single-center retrospective design and short follow-up period,and further multicenter prospective studies are needed to validate the findings.展开更多
Based on atomic crystal configurations,we studied many-body interaction properties of face-centered cubic(fcc)solid argon(Ar)within the atomic distance range of 2.0A to 3.6A at T=300 K.The resulting EOS can accurately...Based on atomic crystal configurations,we studied many-body interaction properties of face-centered cubic(fcc)solid argon(Ar)within the atomic distance range of 2.0A to 3.6A at T=300 K.The resulting EOS can accurately describe the compression behavior of solid Ar under the experimentally investigated pressure range(0~114GPa).Statistically,903(Ar)2 clusters were identified,corresponding to 12 distinct geometric configurations,861(Ar)3 clusters correspond to 25 distinct geometric configurations,816(Ar)4clusters correspond to 27 distinct geometric configurations,and the calculation results exhibited good convergence.For comparative purposes,the EOS of fcc solid Ar was also calculated using a two-body potential-only approach,which showed excellent agreement with experimental data under relevant pressures.Incorporating three-body terms extended the EOS accuracy to 80 GPa,while the inclusion of four-body terms further improved the precision up to 114 GPa.Higher-order many-body terms are expected to enable accurate interpretation of experimental phenomena in solid Ar above 114 GPa.In addition,when the molar volume is reduced to a fixed value,the zero-point vibration pressure has already reached a certain proportion,then it must be considered and cannot be ignored.This study provides a reliable theoretical model for the study of high-pressure properties and zero-point energy of rare gas solids.展开更多
Jargon in English language, part of culture, is a sub-culture. This paper illustrates its connotation, original facts, constructions, functions and characteristics. This study helps us fully recognize British and Amer...Jargon in English language, part of culture, is a sub-culture. This paper illustrates its connotation, original facts, constructions, functions and characteristics. This study helps us fully recognize British and American societies from another angle, and understand diversity of their cultures to benefit English teaching and intercultural communication.展开更多
文摘BACKGROUND Colon polyps represent a significant clinical challenge in elderly patients.While endoscopic mucosal resection(EMR)and argon plasma coagulation(APC)are widely used,their comparative effectiveness in elderly populations remains unclear,particularly regarding postoperative recovery and complication profiles.AIM To compare the postoperative recovery,complications and efficacy of EMR and APC in elderly patients with colonic polyps.METHODS We retrospectively analyzed clinical data from 224 elderly patients with colon polyps treated at our center between January 2021 and July 2024.All patients were divided into the EMR group and APC group according to the surgical method they received.By comparing the operation time,intraoperative bleeding situation,hospital stays,postoperative inflammatory response index,complication rate and recurrence status of the two groups,the effect of the two surgical methods was comprehensively evaluated.RESULTS The APC group exhibited superior outcomes in terms of operative time(10.63 minutes vs 13.27 minutes,P<0.001),intraoperative bleeding situation(39.00%vs 52.42%,P=0.031),and length of hospital stay(1.63 days vs 3.87 days,P<0.001)compared to the EMR group.The one-time resection rate of the APC group(94.69%)was higher than that of the EMR group(89.14%)(P=0.026).The overall effective rates of the two groups were 94.35%and 92.00%,respectively.Postoperative procalcitonin and C-reactive protein levels were lower in the APC group than in the EMR group(P<0.001).The incidence of complications was comparable between the two groups(P=0.159).The recurrence rate was lower in the APC group(2.00%)than in the EMR group(8.06%)(P=0.045).CONCLUSION For elderly patients with colon polyps,APC showed certain advantages compared with EMR in promoting postoperative recovery,reducing the inflammatory response and the risk of complications.However,the study is limited by its single-center retrospective design and short follow-up period,and further multicenter prospective studies are needed to validate the findings.
基金sponsored by the Youth Talent(team)project of Gansu Province(Grant No.2025QNTD12)the Natural ScienceFoundation of Gansu Province(Grant No.25JRRM001,23JRRM0755).
文摘Based on atomic crystal configurations,we studied many-body interaction properties of face-centered cubic(fcc)solid argon(Ar)within the atomic distance range of 2.0A to 3.6A at T=300 K.The resulting EOS can accurately describe the compression behavior of solid Ar under the experimentally investigated pressure range(0~114GPa).Statistically,903(Ar)2 clusters were identified,corresponding to 12 distinct geometric configurations,861(Ar)3 clusters correspond to 25 distinct geometric configurations,816(Ar)4clusters correspond to 27 distinct geometric configurations,and the calculation results exhibited good convergence.For comparative purposes,the EOS of fcc solid Ar was also calculated using a two-body potential-only approach,which showed excellent agreement with experimental data under relevant pressures.Incorporating three-body terms extended the EOS accuracy to 80 GPa,while the inclusion of four-body terms further improved the precision up to 114 GPa.Higher-order many-body terms are expected to enable accurate interpretation of experimental phenomena in solid Ar above 114 GPa.In addition,when the molar volume is reduced to a fixed value,the zero-point vibration pressure has already reached a certain proportion,then it must be considered and cannot be ignored.This study provides a reliable theoretical model for the study of high-pressure properties and zero-point energy of rare gas solids.
文摘Jargon in English language, part of culture, is a sub-culture. This paper illustrates its connotation, original facts, constructions, functions and characteristics. This study helps us fully recognize British and American societies from another angle, and understand diversity of their cultures to benefit English teaching and intercultural communication.
