The photoplethysmogram(PPG) of a pulse wave,similar in appearance to the arterial blood pressure(ABP) waveform,contains rich information about the cardiovascular system.The decay time constant RC,equal to the product ...The photoplethysmogram(PPG) of a pulse wave,similar in appearance to the arterial blood pressure(ABP) waveform,contains rich information about the cardiovascular system.The decay time constant RC,equal to the product of peripheral resistance R and total arterial compliance C,is a meaningful cardiovascular model parameter in vascular assessment.Using or ameliorating the existing ABP methods does not achieve a satisfactory estimation of RC from the PPG volume pulse(VRC).Thus,a novel non-iterative shape method(NSM) of evaluating VRC is introduced in this paper.The mathematic expression between a novel,readily available morphological parameter called the area difference ratio(ADR) and VRC was established.As it was difficult to calculate VRC from the complicated expression analytically,we recommend estimating it using a piecewise linear interpolation criterion.Also,since the effect of the PPG magnitude is eliminated in the calculation of ADR,precaliberation or normalization is dispensable in the NSM.Results of human experiments indicated that the NSM was computationally efficient,and the simulation experiments confirmed that the NSM was theoretically available for ABP.展开更多
基金Project (No.81070885) supported by the National Natural Science Foundation of China
文摘The photoplethysmogram(PPG) of a pulse wave,similar in appearance to the arterial blood pressure(ABP) waveform,contains rich information about the cardiovascular system.The decay time constant RC,equal to the product of peripheral resistance R and total arterial compliance C,is a meaningful cardiovascular model parameter in vascular assessment.Using or ameliorating the existing ABP methods does not achieve a satisfactory estimation of RC from the PPG volume pulse(VRC).Thus,a novel non-iterative shape method(NSM) of evaluating VRC is introduced in this paper.The mathematic expression between a novel,readily available morphological parameter called the area difference ratio(ADR) and VRC was established.As it was difficult to calculate VRC from the complicated expression analytically,we recommend estimating it using a piecewise linear interpolation criterion.Also,since the effect of the PPG magnitude is eliminated in the calculation of ADR,precaliberation or normalization is dispensable in the NSM.Results of human experiments indicated that the NSM was computationally efficient,and the simulation experiments confirmed that the NSM was theoretically available for ABP.
文摘建立了以d5-3-氯-1,2-棕榈酸二酯为内标物,面积比法定量测定食用植物油中3-氯-1,2-丙二醇酯(3-MCPD酯)的气相色谱-质谱检测方法。样品加内标后经甲基叔丁基醚溶解,与甲醇钠-甲醇溶液酯交换反应4 min后加酸性溴化钠终止反应。使用液液萃取法进行萃取后,加0.2 m L苯基硼酸于45℃下衍生20 min,进气相色谱-质谱检测。结果表明:该方法操作简单、灵敏度高,最低检出限为10μg/kg。利用该方法研究了不同植物油精炼过程和冷冻储存时间对3-MCPD酯含量的影响,试验表明脱臭工段是产生3-MCPD酯的主要来源,随着植物油储存时间的延长3-MCPD酯含量呈降低趋势。
