As the Philippines celebrated the 2nd Asia Laboratory Animal Day(ALAD)last November 29,2025,the Philippine Association for Laboratory Animal Sciences(PALAS)reflected on a year marked by growth,collaboration,and renewe...As the Philippines celebrated the 2nd Asia Laboratory Animal Day(ALAD)last November 29,2025,the Philippine Association for Laboratory Animal Sciences(PALAS)reflected on a year marked by growth,collaboration,and renewed commitment to ethical and scientific excellence in animal-based research.Throughout 2025,PALAS has continued to strengthen the laboratory animal science community by advancing education,capacity building,policy advocacy,and regional cooperation.These efforts underscore PALAS’vital role in shaping a culture of responsible animal research aligned with international standards.展开更多
Remembrance activities can support the Culture of Care(CoC)in Laboratory Animal Science(LAS)not only by promoting a culture of respect,gratitude and thankfulness for animal life but also by helping the emotional proce...Remembrance activities can support the Culture of Care(CoC)in Laboratory Animal Science(LAS)not only by promoting a culture of respect,gratitude and thankfulness for animal life but also by helping the emotional processing and healing of lab animal researchers and animal facility staff.Even though remembrance activities are practiced in many parts of the world,we did not come across any reported cases in Sri Lanka before 2022.Therefore,here,we report on the various remembrance activities and practices observed within our local scientific community.展开更多
Malaysia's commemoration of the second Asia Laboratory Animal Day(ALAD)in 2025 marked a notable step forward in strengthening national and regional laboratory animal science,ethical governance,and humane research ...Malaysia's commemoration of the second Asia Laboratory Animal Day(ALAD)in 2025 marked a notable step forward in strengthening national and regional laboratory animal science,ethical governance,and humane research practices.Celebrated a day earlier on 28 November,an initiative led by the Laboratory Animal Science Association of Malaysia(LASAM),comprised a coordinated three-month programme from September to November.A series of targeted activities were conducted,including professional exchange visits,competency-based rodent care and use workshops,refinement-centred blood sampling training,and institutional lectures on ethics and welfare.These engagements involved researchers,technicians,ethics committee members,and undergraduate trainees;reflecting ALAD's aim of fostering ethical awareness and technical proficiency across all levels of research personnel.A major highlight of the campaign was the signing of a Memorandum of Understanding between LASAM and Universiti Teknologi MARA(UiTM),strengthening long-term collaboration in training,welfare standard harmonisation,and shared ethical governance.The programme also delivered measurable outcomes:over 92%of participants improved their understanding of the 3Rs and humane endpoints,more than 95%attained competency in basic rodent handling,and national interest in laboratory animal science increased,as reflected by rising LASAM membership.Malaysia's ALAD initiatives emphasise the importance of grassroots engagement,refinement-based training,and strong institutional partnerships in advancing ethical and humane science.The country's experience provides a replicable framework for other Asian regions seeking to enhance welfare capacity,harmonise standards,and cultivate responsible research communities.Malaysia remains committed to supporting ALAD's ongoing mission to advance scientific integrity and animal welfare across Asia.展开更多
Editorial message Every advancement in the field of laboratory animal science and technology,from exploring basic mechanisms to validating the development of new drugs,and from establishing disease models to respondin...Editorial message Every advancement in the field of laboratory animal science and technology,from exploring basic mechanisms to validating the development of new drugs,and from establishing disease models to responding to public health emergencies,strengthens the foundation for human health and well-being,serving as an important cornerstone for promoting global scientific innovation.For this reason.展开更多
Background: With the aim of establishing the most comprehensive database of laboratory animal strains, the "laboratory animal strain resources database"(LasDB)was constructed as a searchable online database ...Background: With the aim of establishing the most comprehensive database of laboratory animal strains, the "laboratory animal strain resources database"(LasDB)was constructed as a searchable online database of all laboratory animal strains,stocks and mutant embryonic stem-cell lines available worldwide, including inbred,outbred, mutant and genetically engineered strains.Methods: MySQL database software was used to construct the LasDB, offering an easy-to-use interface.Results: To date, LasDB has a collection covering data for 21 596 mouse strains,2062 rat strains, 13 monkey strains, 2 hamster strains, 5 dog strains, 5 rabbit strains and more than 50 other laboratory animal strains. LasDB will be continually improved with regular updates of new laboratory animal strains from all over the world.Conclusion: To the best of our knowledge, this is the first database that attempts to systematically integrate all available laboratory animal strain data with the aim of supporting open usage and full resource sharing.展开更多
The 14th Scientific Congress of the Chinese Association for Laboratory Animal Science was held on October 11‐12,2018 in Qingdao,China.During this congress,an international forum on the development of Laboratory Anima...The 14th Scientific Congress of the Chinese Association for Laboratory Animal Science was held on October 11‐12,2018 in Qingdao,China.During this congress,an international forum on the development of Laboratory Animal Sciences(LAS)worldwide was held in which participants learnt about the development of new LAS resources and technologies,as well as the progress of LAS in China.The main points that were discussed are as follows.After nearly a century of development,there are more than 200 species of experimental animals,and more than 20 000 inbred lines,outbred lines,genetic engineered animals,animal models of diseases,and other resources all over the world,which provide abundant experimental animal resources for scientific research.These resources are widely used in life science research.展开更多
The Second Online Academic Salon on Monkeypox Virus: One Health, monkeypox prevention, and treatment was held online on August 26, 2022, at Beijing, China. The Academic Salon was hosted by the Chinese Association for ...The Second Online Academic Salon on Monkeypox Virus: One Health, monkeypox prevention, and treatment was held online on August 26, 2022, at Beijing, China. The Academic Salon was hosted by the Chinese Association for Laboratory Animal Sciences(CALAS);organized by the Editorial Office of Animal Models and Experimental Medicine( AMEM), Acta Laboratorium Animalis Scientia Sinica, and the Chinese Journal of Comparative Medicine;and co-organized by the China Union of Life Science Societies and Wiley Press. This online salon was simultaneously broadcast live, and attracted more than 2000 participants online from home and abroad.展开更多
The First Academic Salon on Monkeypox Virus was held online on June 10th,2022 in Beijing,China.The Academic Salon was hosted by the Chinese Association for Laboratory Animal Sciences (CALAS);organized by the Editorial...The First Academic Salon on Monkeypox Virus was held online on June 10th,2022 in Beijing,China.The Academic Salon was hosted by the Chinese Association for Laboratory Animal Sciences (CALAS);organized by the Editorial Office of Animal Models and Experimental Medicine (AMEM),Acta Laboratorium Animalis Scientia Sinica,and the Chinese Journal of Comparative Medicine,and co-organized by China Union of Life Science Societies.This Academic Salon was also broadcast live on Wiley WeChat Video Channel,and attracted over 2400online attendees home and abroad.展开更多
The Faculty of Medicine, University of Colombo(UCFM), is the forerunner in the laboratory animal science(LAS) field in Sri Lanka. Here laboratory animals such as rats, frogs and rabbits were used in medical education ...The Faculty of Medicine, University of Colombo(UCFM), is the forerunner in the laboratory animal science(LAS) field in Sri Lanka. Here laboratory animals such as rats, frogs and rabbits were used in medical education to demonstrate physiological principles in the early 1950 s. The establishment of the first animal house in 1969 at UCFM better facilitated the use of laboratory animals in medical education and research. By 2006, lack of ethical guide lines was an issue and a set of ethical guidelines was developed and published in 2009, which today are followed by researchers and reviewers in many universities and research institutions in the country. With this development, there was a need for an organized system of education for the LAS discipline. This was fulfilled by conducting the first certificate course on LAS in the Asian region in 2011 in collaboration with the Utrecht University,Netherlands. The Sri Lanka Association for LAS has continued LAS education since its establishment in 2012 at UCFM by conducting workshops and short courses.展开更多
The Institute of Laboratory Animal Sciences(ILAS)is a unique research organization dedicated to research on laboratory animals and comparative medicine.It is affi liated with the Chinese Academy of Medical Sciences(CA...The Institute of Laboratory Animal Sciences(ILAS)is a unique research organization dedicated to research on laboratory animals and comparative medicine.It is affi liated with the Chinese Academy of Medical Sciences(CAMS)and Peking Union Medical College(PUMC).It was founded in 1980,when China has just begun to develop laboratory animal sciences.ILAS currently has 478 staff working in four main business areas:scientifi c research;laboratory animal resource development conservation and production;comparative medicine technology services;and teaching and training.展开更多
The Institute of Laboratory Animal Sciences(ILAS)is a unique research organization dedicated to research on laboratory animals and comparative medicine.It is affi liated with the Chinese Academy of Medical Sciences(CA...The Institute of Laboratory Animal Sciences(ILAS)is a unique research organization dedicated to research on laboratory animals and comparative medicine.It is affi liated with the Chinese Academy of Medical Sciences(CAMS)and Peking Union Medical College(PUMC).It was founded in 1980,when China has just begun to develop laboratory animal sciences.ILAS currently has 478 staff working in four main business areas:scientifi c research;laboratory animal resource development conservation and production;comparative medicine technology services;and teaching and training.展开更多
The Chinese Association for Laboratory Animal Sciences(CALAS)was founded in 1987.Qian Xin-zhong,the former minister of the Ministry of Health,was the president of the fi rst session of the Council.CALAS has now comple...The Chinese Association for Laboratory Animal Sciences(CALAS)was founded in 1987.Qian Xin-zhong,the former minister of the Ministry of Health,was the president of the fi rst session of the Council.CALAS has now completed seven sessions of the Council.The current president is Prof.Chuan Qin,the director of the Institute of Laboratory Animal Sciences,Chinese Academy of Medical Sciences(CAMS)&Peking Union Medical College(PUMC).CALAS oversees 16 work Committees,such as the Academic Committee,Journal and Information Committee,International Exchange and Cooperation Committee,as well as 16 professional Committees,e.g.Laboratory Animal Welfare and Ethics Professional Committee and Laboratory Animal Standardization Professional Committee.展开更多
The Chinese Association for Laboratory Animal Sciences(CALAS)was founded in 1987.Qian Xin-zhong,the former minister of the Ministry of Health,was the president of the first session of the Council.CALAS has now complet...The Chinese Association for Laboratory Animal Sciences(CALAS)was founded in 1987.Qian Xin-zhong,the former minister of the Ministry of Health,was the president of the first session of the Council.CALAS has now completed seven sessions of the Council.The current president is Prof.Chuan Qin,the director of the Institute of Laboratory Animal Sciences,Chinese Academy of Medical Sciences(CAMS)&Peking Union Medical College(PUMC).CALAS oversees 16 work Committees,such as the Academic Committee,Journal and Information Committee,International Exchange and Cooperation Committee,as well as 16 professional Committees,e.g.Laboratory Animal Welfare and Ethics Professional Committee and Laboratory Animal Standardization Professional Committee.展开更多
The Chinese Association for Laboratory Animal Sciences(CALAS)was founded in 1987.Qian Xin-zhong,the former minister of the Ministry of Health,was the president of the fi rst session of the Council.CALAS has now comple...The Chinese Association for Laboratory Animal Sciences(CALAS)was founded in 1987.Qian Xin-zhong,the former minister of the Ministry of Health,was the president of the fi rst session of the Council.CALAS has now completed seven sessions of the Council.The current president is Prof.Chuan Qin,the director of the Institute of Laboratory Animal Sciences,Chinese Academy of Medical Sciences(CAMS)&Peking Union Medical College(PUMC).CALAS oversees 16 work Committees,such as the Academic Committee,Journal and Information Committee,International Exchange and Cooperation Committee,as well as 16 professional Committees,e.g.Laboratory Animal Welfare and Ethics Professional Committee and Laboratory Animal Standardization Professional Committee.展开更多
The tree shrew （Tupaia belangeri） is a promising laboratory animal that possesses a closer genetic relationship to primates than to rodents. In addition, advantages such as small size, easy breeding, and rapid repro...The tree shrew （Tupaia belangeri） is a promising laboratory animal that possesses a closer genetic relationship to primates than to rodents. In addition, advantages such as small size, easy breeding, and rapid reproduction make the tree shrew an ideal subject for the study of human disease. Numerous tree shrew disease models have been generated in biological and medical studies in recent years. Here we summarize current tree shrew disease models, including models of infectious diseases, cancers, depressive disorders, drug addiction, myopia, metabolic diseases, and immune-related diseases. With the success of tree shrew transgenic technology, this species will be increasingly used in biological and medical studies in the future.展开更多
文摘As the Philippines celebrated the 2nd Asia Laboratory Animal Day(ALAD)last November 29,2025,the Philippine Association for Laboratory Animal Sciences(PALAS)reflected on a year marked by growth,collaboration,and renewed commitment to ethical and scientific excellence in animal-based research.Throughout 2025,PALAS has continued to strengthen the laboratory animal science community by advancing education,capacity building,policy advocacy,and regional cooperation.These efforts underscore PALAS’vital role in shaping a culture of responsible animal research aligned with international standards.
文摘Remembrance activities can support the Culture of Care(CoC)in Laboratory Animal Science(LAS)not only by promoting a culture of respect,gratitude and thankfulness for animal life but also by helping the emotional processing and healing of lab animal researchers and animal facility staff.Even though remembrance activities are practiced in many parts of the world,we did not come across any reported cases in Sri Lanka before 2022.Therefore,here,we report on the various remembrance activities and practices observed within our local scientific community.
文摘Malaysia's commemoration of the second Asia Laboratory Animal Day(ALAD)in 2025 marked a notable step forward in strengthening national and regional laboratory animal science,ethical governance,and humane research practices.Celebrated a day earlier on 28 November,an initiative led by the Laboratory Animal Science Association of Malaysia(LASAM),comprised a coordinated three-month programme from September to November.A series of targeted activities were conducted,including professional exchange visits,competency-based rodent care and use workshops,refinement-centred blood sampling training,and institutional lectures on ethics and welfare.These engagements involved researchers,technicians,ethics committee members,and undergraduate trainees;reflecting ALAD's aim of fostering ethical awareness and technical proficiency across all levels of research personnel.A major highlight of the campaign was the signing of a Memorandum of Understanding between LASAM and Universiti Teknologi MARA(UiTM),strengthening long-term collaboration in training,welfare standard harmonisation,and shared ethical governance.The programme also delivered measurable outcomes:over 92%of participants improved their understanding of the 3Rs and humane endpoints,more than 95%attained competency in basic rodent handling,and national interest in laboratory animal science increased,as reflected by rising LASAM membership.Malaysia's ALAD initiatives emphasise the importance of grassroots engagement,refinement-based training,and strong institutional partnerships in advancing ethical and humane science.The country's experience provides a replicable framework for other Asian regions seeking to enhance welfare capacity,harmonise standards,and cultivate responsible research communities.Malaysia remains committed to supporting ALAD's ongoing mission to advance scientific integrity and animal welfare across Asia.
文摘Editorial message Every advancement in the field of laboratory animal science and technology,from exploring basic mechanisms to validating the development of new drugs,and from establishing disease models to responding to public health emergencies,strengthens the foundation for human health and well-being,serving as an important cornerstone for promoting global scientific innovation.For this reason.
基金the Central Research Institutes Basic Operating Grants,Grant/Award Number:DWS201512CAMS Innovation Fund for Medical Sciences(CIFMS),Grant/Award Number:2016-I2M-2-006-03National Major Scientific and Technological Special Project for Key Infectious Diseases,Grant/Award Number:2017ZX10304402-001
文摘Background: With the aim of establishing the most comprehensive database of laboratory animal strains, the "laboratory animal strain resources database"(LasDB)was constructed as a searchable online database of all laboratory animal strains,stocks and mutant embryonic stem-cell lines available worldwide, including inbred,outbred, mutant and genetically engineered strains.Methods: MySQL database software was used to construct the LasDB, offering an easy-to-use interface.Results: To date, LasDB has a collection covering data for 21 596 mouse strains,2062 rat strains, 13 monkey strains, 2 hamster strains, 5 dog strains, 5 rabbit strains and more than 50 other laboratory animal strains. LasDB will be continually improved with regular updates of new laboratory animal strains from all over the world.Conclusion: To the best of our knowledge, this is the first database that attempts to systematically integrate all available laboratory animal strain data with the aim of supporting open usage and full resource sharing.
文摘The 14th Scientific Congress of the Chinese Association for Laboratory Animal Science was held on October 11‐12,2018 in Qingdao,China.During this congress,an international forum on the development of Laboratory Animal Sciences(LAS)worldwide was held in which participants learnt about the development of new LAS resources and technologies,as well as the progress of LAS in China.The main points that were discussed are as follows.After nearly a century of development,there are more than 200 species of experimental animals,and more than 20 000 inbred lines,outbred lines,genetic engineered animals,animal models of diseases,and other resources all over the world,which provide abundant experimental animal resources for scientific research.These resources are widely used in life science research.
文摘The Second Online Academic Salon on Monkeypox Virus: One Health, monkeypox prevention, and treatment was held online on August 26, 2022, at Beijing, China. The Academic Salon was hosted by the Chinese Association for Laboratory Animal Sciences(CALAS);organized by the Editorial Office of Animal Models and Experimental Medicine( AMEM), Acta Laboratorium Animalis Scientia Sinica, and the Chinese Journal of Comparative Medicine;and co-organized by the China Union of Life Science Societies and Wiley Press. This online salon was simultaneously broadcast live, and attracted more than 2000 participants online from home and abroad.
文摘The First Academic Salon on Monkeypox Virus was held online on June 10th,2022 in Beijing,China.The Academic Salon was hosted by the Chinese Association for Laboratory Animal Sciences (CALAS);organized by the Editorial Office of Animal Models and Experimental Medicine (AMEM),Acta Laboratorium Animalis Scientia Sinica,and the Chinese Journal of Comparative Medicine,and co-organized by China Union of Life Science Societies.This Academic Salon was also broadcast live on Wiley WeChat Video Channel,and attracted over 2400online attendees home and abroad.
基金Grants/funds provided by the National Science Foundation of Sri Lanka,The American Physiological Society,AAALAC International,Laboratory Animals Limited of UK,ICLAS and the AFLAS-ETALAST program for the activities conducted by UCFM and SLALAS leading to the development of the LAS field in Sri Lanka are greatly appreciated
文摘The Faculty of Medicine, University of Colombo(UCFM), is the forerunner in the laboratory animal science(LAS) field in Sri Lanka. Here laboratory animals such as rats, frogs and rabbits were used in medical education to demonstrate physiological principles in the early 1950 s. The establishment of the first animal house in 1969 at UCFM better facilitated the use of laboratory animals in medical education and research. By 2006, lack of ethical guide lines was an issue and a set of ethical guidelines was developed and published in 2009, which today are followed by researchers and reviewers in many universities and research institutions in the country. With this development, there was a need for an organized system of education for the LAS discipline. This was fulfilled by conducting the first certificate course on LAS in the Asian region in 2011 in collaboration with the Utrecht University,Netherlands. The Sri Lanka Association for LAS has continued LAS education since its establishment in 2012 at UCFM by conducting workshops and short courses.
文摘The Institute of Laboratory Animal Sciences(ILAS)is a unique research organization dedicated to research on laboratory animals and comparative medicine.It is affi liated with the Chinese Academy of Medical Sciences(CAMS)and Peking Union Medical College(PUMC).It was founded in 1980,when China has just begun to develop laboratory animal sciences.ILAS currently has 478 staff working in four main business areas:scientifi c research;laboratory animal resource development conservation and production;comparative medicine technology services;and teaching and training.
文摘The Institute of Laboratory Animal Sciences(ILAS)is a unique research organization dedicated to research on laboratory animals and comparative medicine.It is affi liated with the Chinese Academy of Medical Sciences(CAMS)and Peking Union Medical College(PUMC).It was founded in 1980,when China has just begun to develop laboratory animal sciences.ILAS currently has 478 staff working in four main business areas:scientifi c research;laboratory animal resource development conservation and production;comparative medicine technology services;and teaching and training.
文摘The Chinese Association for Laboratory Animal Sciences(CALAS)was founded in 1987.Qian Xin-zhong,the former minister of the Ministry of Health,was the president of the fi rst session of the Council.CALAS has now completed seven sessions of the Council.The current president is Prof.Chuan Qin,the director of the Institute of Laboratory Animal Sciences,Chinese Academy of Medical Sciences(CAMS)&Peking Union Medical College(PUMC).CALAS oversees 16 work Committees,such as the Academic Committee,Journal and Information Committee,International Exchange and Cooperation Committee,as well as 16 professional Committees,e.g.Laboratory Animal Welfare and Ethics Professional Committee and Laboratory Animal Standardization Professional Committee.
文摘The Chinese Association for Laboratory Animal Sciences(CALAS)was founded in 1987.Qian Xin-zhong,the former minister of the Ministry of Health,was the president of the first session of the Council.CALAS has now completed seven sessions of the Council.The current president is Prof.Chuan Qin,the director of the Institute of Laboratory Animal Sciences,Chinese Academy of Medical Sciences(CAMS)&Peking Union Medical College(PUMC).CALAS oversees 16 work Committees,such as the Academic Committee,Journal and Information Committee,International Exchange and Cooperation Committee,as well as 16 professional Committees,e.g.Laboratory Animal Welfare and Ethics Professional Committee and Laboratory Animal Standardization Professional Committee.
文摘The Chinese Association for Laboratory Animal Sciences(CALAS)was founded in 1987.Qian Xin-zhong,the former minister of the Ministry of Health,was the president of the fi rst session of the Council.CALAS has now completed seven sessions of the Council.The current president is Prof.Chuan Qin,the director of the Institute of Laboratory Animal Sciences,Chinese Academy of Medical Sciences(CAMS)&Peking Union Medical College(PUMC).CALAS oversees 16 work Committees,such as the Academic Committee,Journal and Information Committee,International Exchange and Cooperation Committee,as well as 16 professional Committees,e.g.Laboratory Animal Welfare and Ethics Professional Committee and Laboratory Animal Standardization Professional Committee.
基金supported by the National Nature Science Foundation of China(81325016,U1602221,81322038 and U1502222)
文摘The tree shrew （Tupaia belangeri） is a promising laboratory animal that possesses a closer genetic relationship to primates than to rodents. In addition, advantages such as small size, easy breeding, and rapid reproduction make the tree shrew an ideal subject for the study of human disease. Numerous tree shrew disease models have been generated in biological and medical studies in recent years. Here we summarize current tree shrew disease models, including models of infectious diseases, cancers, depressive disorders, drug addiction, myopia, metabolic diseases, and immune-related diseases. With the success of tree shrew transgenic technology, this species will be increasingly used in biological and medical studies in the future.
