Objective Blood culture remains the gold standard for diagnosing bloodstream infections.Clinical laboratories must ensure the quality of blood culture processes from receipt to obtaining definitive results.We examined...Objective Blood culture remains the gold standard for diagnosing bloodstream infections.Clinical laboratories must ensure the quality of blood culture processes from receipt to obtaining definitive results.We examined laboratory analytical indicators associated with positive blood culture results.Methods Blood cultures collected from Peking Union Medical College Hospital between January 1,2020,and December 31,2022,were retrospectively analyzed.The mode of transportation(piping logistics delivery vs.staff),source of blood cultures(outpatient/emergency department vs.inpatient department),rotation of personnel,and time of reception(8:00–19:59 vs.20:00–07:59)were compared between blood culture-positive and-negative results.Results Between 2020 and 2022,the total positive rate of blood culture was 8.07%.The positive rate of blood cultures in the outpatient/emergency department was significantly higher than that in the inpatient department(12.46%vs.5.83%;P<0.0001).The time-to-detection of blood cultures was significantly affected by the delivery mode and personnel rotation.The blood culture positive rate of the total pre-analytical time within 1 h was significantly higher than that within 1–2 h or>2 h(P<0.0170).Conclusion Laboratory analytical indicators such as patient source,transportation mode,and personnel rotation significantly impacted the positive detection rate or time of blood culture.展开更多
BACKGROUND Gastrointestinal endoscopy technology has significantly improved the diagnostic accuracy and the successful treatment of gastrointestinal diseases.However,a series of ethical issues have emerged,such as exp...BACKGROUND Gastrointestinal endoscopy technology has significantly improved the diagnostic accuracy and the successful treatment of gastrointestinal diseases.However,a series of ethical issues have emerged,such as expanding treatment indications,which affect the fair distribution of medical resources.There is limited research on ethical issues in the field of digestive endoscopy.AIM To investigate the level of ethical awareness among gastrointestinal endoscopy practitioners and analyze the ethical issues involved in gastrointestinal endoscopy technology.METHODS A questionnaire survey was performed to collect relevant data(gender,age,degree of education,professional title,personnel category,the level of understanding medical ethical principles,ethics training and its learning pathways)from gastrointestinal endoscopy practitioners at the Second Hospital of Dalian Medical University and Dalian Friendship Hospital,including licensed physicians and nurses(including trainees and graduate students).RESULTS The majority of gastrointestinal endoscopy practitioners have received training on ethics,but there is still considerable room for improvement in their ethical awareness.Different learning pathways may affect the mastery of ethical principles, and understanding of ethical principles is more easily achieved through hospital ethics institutions.CONCLUSIONTo address the ethical issues in gastrointestinal endoscopy technology, it is necessary to enhance the humanisticeducation of gastrointestinal endoscopy practitioners, incorporate ethical standards into the technology assessmentprocess, and establish a patient-centered diagnostic and treatment model to improve the ethical awareness of practitionersand achieve a balance between technology and ethics.展开更多
Does traditional Chinese economic thought possess genuine analytical rigor?This question lies at the heart of any serious evaluation of its theoretical value and historical significance.It also matters for understandi...Does traditional Chinese economic thought possess genuine analytical rigor?This question lies at the heart of any serious evaluation of its theoretical value and historical significance.It also matters for understanding how best to preserve,build on its remarkable achievements,and develop its intellectual legacy.Critics such as Schumpeter and Taylor have long argued that the economic reasoning found in ancient China cannot compare with that of classical Greece or medieval Europe.Yet this view often reflects the narrow assumptions of mainstream economics,defining analysis almost entirely in terms of market exchange.As a result,it tends to overlook traditions built around statecraft,governance,and the management of economic order.A careful re-examination and Sino-Western comparative analysis of key thinkers-including Mencius,Guanzi,and Sima Qian-tells a different story.Rooted in China’s distinctive cultural and philosophical heritage,traditional Chinese economic thought not only contains the analytical dimensions(as defined by Schumpeter)but also displays a broader and more diverse set of economic reasoning.Notably,its systematic depth and intellectual precision were,in many respects,remarkably advanced.Therefore,advancing the construction of a Chinese school of economics in the new era under the framework of the“Second Integration”,i.e.,integrating the basic tenets of Marxism with China’s fine traditional culture,should,and indeed can draw essential insights from this analytical tradition.展开更多
Existing evidence suggests residential greenness is beneficial to human,while no research to date explored the associations of greenness with age-related macular degeneration(AMD).To evaluate the association of greenn...Existing evidence suggests residential greenness is beneficial to human,while no research to date explored the associations of greenness with age-related macular degeneration(AMD).To evaluate the association of greenness with AMD,modification and mediation effect of air pollution,we conducted this prospective study.We con-structed weighted quantile sum(WQS)index as co-exposure to nitrogen oxides(NO_(x)),particulate matter<2.5μm(PM_(2.5)),particulate matter<10μm(PM10).Stratified Cox regression models were applied to test the effect of exposure.Effect modification of air pollution was assessed.Stratified Cox models through the indirect method and Aalen additive risk models were used in mediation analysis.Over median follow-up of 11.67 years,4596 AMD events were ascertained.Hazard ratios(HRs)and 95%confidence intervals(95%CIs)of incident AMD for pollution per interquartile range(IQR)increment were 1.10(1.04–1.16)for nitrogen dioxide(NO_(2)),1.09(1.03–1.15)for NO_(x),1.14(1.05–1.24)for PM_(2.5),1.13(1.05–1.21)for PM10.The HR(95%CI)of AMD associated with greenness 1000 m buffer per IQR increment was 0.91(0.86–0.97),300 m buffer was 0.94(0.89–0.99).The as-sociation between greenness 1000 m and AMD was 28.59%,44.77%,35.59%,32.31%and 27.08%mediated by the decreased WQS index,NO_(2),NO_(x),PM_(2.5) and PM10,respectively.Increased greenness was associated with lower AMD incidence,and air pollution partly mediate it,which implies that interventions aimed at improving air quality and increasing greenness could have a dual benefit in mitigating AMD risk.展开更多
Background:Despite highly effective vaccines against SARS-CoV-2,COVID-19 vaccine hesitancy persisted in some populations in England during the pandemic,with rates and motivations for hesitancy varying by demographic g...Background:Despite highly effective vaccines against SARS-CoV-2,COVID-19 vaccine hesitancy persisted in some populations in England during the pandemic,with rates and motivations for hesitancy varying by demographic group.Addressing the drivers of vaccine hesitancy through targeted interventions in hesitant groups is a public health priority for better and more rapid control of disease spread.We aimed to characterise the determinants and subtypes of vaccine hesitancy and identify more persistent forms of hesitancy via analysis of vaccine uptake in a large cross-sectional cohort with linked National Health Service(NHS)data.展开更多
Background:To determine whether initiating a glucagon-like peptide-1 receptor agonist(GLP-1 RA)within 3 months of type 2 diabetes(T2DM)diagnosis alters the subsequent risk of overall and site-specific cancer and wheth...Background:To determine whether initiating a glucagon-like peptide-1 receptor agonist(GLP-1 RA)within 3 months of type 2 diabetes(T2DM)diagnosis alters the subsequent risk of overall and site-specific cancer and whether this association differs by baseline body-mass index(BMI).Methods:This retrospective cohort study used electronic health records from the TriNetX U.S.research network.Adults aged 20 years or older diagnosed with T2DM between 2016 and 2024 were included if they received any hypoglycemic agents within 3 months before and after diagnosis.Following 1:1 propensity score matching,both the GLP-1 RA user and non-user groups included 183,264 patients.The study outcome was defined as a diagnosis of malignant neoplasms.Hazard ratios(HRs)for overall and site-specific cancer risk were estimated using Cox proportional hazards models.Kaplan–Meier analysis and stratified analysis by BMI were performed.Results:Early GLP-1 RA use demonstrated a modest but significant association with reduced overall cancer risk(HR 0.93;95%CI:0.90–0.96).Reduced risks were noted for cancers of the digestive(HR 0.81),respiratory(HR 0.66),and female genital(HR 0.87)systems.In stratified analysis,benefits were more pronounced in patients with BMI≥30,particularly for pancreatic and colorectal cancers.Conclusion:Early initiation of GLP-1 receptor agonists in patients with diagnosed T2DM was associated with a modest reduction in overall cancer risk,particularly among individuals with obesity.These findings highlight the dual metabolic and oncologic value of prompt GLP-1 RA therapy.展开更多
Fully grouted rock bolts have been used in mining industry for many years.Much research has been conducted to evaluate the load transfer behavior of fully grouted rock bolts with experimental programs.However,compared...Fully grouted rock bolts have been used in mining industry for many years.Much research has been conducted to evaluate the load transfer behavior of fully grouted rock bolts with experimental programs.However,compared with that,less work has been conducted with analytical modelling.Therefore,in this paper,the authors used an analytical model to study the load transfer behavior of fully grouted rock bolts.To confirm the credibility of this analytical model,an in-situ pull-out test was used to validate this model.There was a close match between the experimental result and the analytical result.Following it,a parametric study was conducted with this analytical model.The influence of coefficients,Young’s modulus of the rock bolt and the diameter of the rock bolt on the load transfer performance of rock bolts was studied.Furthermore,the load distribution along the fully grouted rock bolt was analytically studied.The results show that the axial load in the rock bolt decayed from the loaded end to the free end independent of the pull-out load.However,the trend of the load distribution curve was influenced by the pull-out load.This paper was beneficial for better understanding the load transfer mechanism of fully grouted rock bolts.展开更多
This paper presents an analytical investigation of water hammer in a hydraulic pressurized pipe system with a throttled surge chamber located at the junction between a tunnel and a penstock, and a valve positioned at ...This paper presents an analytical investigation of water hammer in a hydraulic pressurized pipe system with a throttled surge chamber located at the junction between a tunnel and a penstock, and a valve positioned at the downstream end of the penstock. Analytical formulas of maximum water hammer pressures at the downstream end of the tunnel and the valve were derived for a system subjected to linear and slow valve closure. The analytical results were then compared with numerical ones obtained using the method of characteristics. There is agreement between them. The formulas can be applied to estimating water hammer pressure at the valve and transmission of water hammer pressure through the surge chamber at the junction for a hydraulic pipe system with a surge chamber.展开更多
In this paper,an analytical model that represents the streamwise velocity distribution for open channel flow with submerged flexible vegetation is studied.In the present vegetated flow modelling,the whole flow field h...In this paper,an analytical model that represents the streamwise velocity distribution for open channel flow with submerged flexible vegetation is studied.In the present vegetated flow modelling,the whole flow field has been separated into two layers vertically: a vegetated layer and a non-vegetated free-water layer.Within the vegetated layer,an analysis of the mechanisms affecting water flow through flexible vegetation has been conducted.In the non-vegetated layer,a modified log-law equation that represents the velocity profile varying with vegetation height has been investigated.Based on the studied analytical model,a sensitivity analysis has been conducted to assess the influences of the drag (CD) and friction (Cf ) coefficients on the flow velocity.The investigated ranges of CD and Cf have also been compared to published values.The findings suggest that the CD and Cf values are non-constant at different depths and vegetation densities,unlike the constant values commonly suggested in literature.This phenomenon is particularly clear for flows with flexible vegetation,which is characterised by large deflection.展开更多
A closed-form out-of-plane dynamic displacement response of a curved track subjected to moving loads was proposed.The track structure was modeled as a planar curved Timoshenko beam periodically supported by the double...A closed-form out-of-plane dynamic displacement response of a curved track subjected to moving loads was proposed.The track structure was modeled as a planar curved Timoshenko beam periodically supported by the double-layer spring-damping elements.The general dynamic displacement response induced by the moving loads along the curve on the elastic semi-infinite space was firstly obtained in the frequency domain,according to the Duhamel integral and the dynamic reciprocity theorem.In the case of the periodic curved track structure subjected to moving loads,the dynamic displacement equation was simplified into a form of summation within the basic track cell instead of the integral.The transfer function for the curved track was expressed in the form of a transfer matrix.Single and series moving loads were involved in the calculation program.For the verification of the analytical model,the mid-span vertical deflection of a simply support curved beam subjected to moving load was recalculated and compared with the same case in the reference.The research results indicate that:under the same moving loads,the displacement response of the curved track decreases slightly with the increasing track radius,and the displacement response of the curved track with the radius greater than or equal to 600 m is almost equivalent to the displacement response of the straight track;the frequency spectrum of the curved track is more abundant than that of the straight track,which may result in more wheel-rail resonance and rail corrugation in the curved lines.展开更多
The homogeneous balance method was improved and applied to two systems Of nonlinear evolution equations. As a result, several families of exact analytic solutions are derived by some new ansatzs. These solutions conta...The homogeneous balance method was improved and applied to two systems Of nonlinear evolution equations. As a result, several families of exact analytic solutions are derived by some new ansatzs. These solutions contain Wang's and Zhang's results and other new types of analytical solutions, such as rational fraction solutions and periodic solutions. The way can also be applied to solve more nonlinear partial differential equations.展开更多
In this paper, the magneto hydrodynamic (MHD) flow of viscous fluid in a channel with non-parallel plates is studied. The governing partial differential equation was transformed into a system of dimensionless non-simi...In this paper, the magneto hydrodynamic (MHD) flow of viscous fluid in a channel with non-parallel plates is studied. The governing partial differential equation was transformed into a system of dimensionless non-similar coupled ordinary differential equation. The transformed conservations equations were solved by using new algorithm. Basically, this new algorithm depends mainly on the Taylor expansion application with the coefficients of power series resulting from integrating the order differential equation. Results obtained from new algorithm are compared with the results of numerical Range-Kutta fourth-order algorithm with help of the shooting algorithm. The comparison revealed that the resulting solutions were excellent agreement. Thermo-diffusion and diffusion-thermo effects were investigated to analyze the behavior of temperature and concentration profile. Also the influences of the first order chemical reaction and the rate of mass and heat transfer were studied. The computed analytical solution result for the velocity, temperature and concentration distribution with the effect of various important dimensionless parameters was analyzed and discussed graphically.展开更多
The long-term stability of the roof is particularly important in designing underground rock structures.To estimate the durability of roof strata in underground excavation,a computation scheme of subcritical crack grow...The long-term stability of the roof is particularly important in designing underground rock structures.To estimate the durability of roof strata in underground excavation,a computation scheme of subcritical crack growth is proposed in this study.By adopting the proposed method,the potential collapse location of strata is derivable in accordance with a static model,the durability of roof strata can be estimated,a dynamic time step control strategy is achieved to balance the accuracy and speed of computing,and the initial crack size of rock can be estimated.In addition to the above,a mechanical model of underground excavation with non-uniformly distributed loads and partially yielded foundation is presented as the prototypical case.A set of case studies is carried out that showcase a power correlation between applied stress and roof durability.The allowable applied tensile stress for a 100-year life cycle is about 76%of the tensile strength.By using the proposed subcritical crack growth computation scheme,the roof stability in an underground excavation can be identified not only from the spatial view but also from the temporal perspective.展开更多
In the present scenario,tapping the unutilised hydropower potential is one of the highest priorities in developing countries of the world.Special emphasis is being imparted to run of the river(RoR)mode of power genera...In the present scenario,tapping the unutilised hydropower potential is one of the highest priorities in developing countries of the world.Special emphasis is being imparted to run of the river(RoR)mode of power generation.However,the governments are now facing the dilemma whether to promote small hydropower projects(SHPs) or encourage large hydropower projects(LHPs).RoR large hydropower projects result into large scale cutting of mountains for constructing tunnels and access roads,generation of huge quantity of muck and large scale impact on flora and fauna due to diversion of rivers/streams.On the other hand,though SHPs are claimed to be greener and more sustainable by a section of researchers and energy planners but,they will be required to be set up in large number to generate equivalent amount of electricity.The aim of this study is to rank the most sustainable installed capacity range of RoR hydropower projects.To achieve this aim,the study proposes the use of quite popular multi-criteria decision making(MCDM)method of Operation Research named Analytical Hierarchy Process.A case study has been presented from Himachal Pradesh,a hydro rich state located in the western Himalayan region.As per sustainability assessment carried out in this study,hydropower projects in the capacity range 1 to 5 MW have been ranked to be the most sustainable.展开更多
Strengthening reinforced concrete (R. C.) beams using prestressed glass fiber-reinforced polymer (PGFRP) was studied experimentally as described in Part I of this paper (Huang et al., 2005). In that paper, R. C. beams...Strengthening reinforced concrete (R. C.) beams using prestressed glass fiber-reinforced polymer (PGFRP) was studied experimentally as described in Part I of this paper (Huang et al., 2005). In that paper, R. C. beams, R. C. beams with GFRP (glass fiber-reinforced polymer) sheets, and R. C. beams with PGFRP sheets were tested in both under-strengthened and over-strengthened cases. The test results showed that the load-carrying capacities (ultimate loads) of the beams with GFRP sheets were greater than those of the beams without polymer sheets. The load-carrying capacities of beams with PGFRP sheets were greater than those of beams with GFRP sheets. The objective of this work is to develop an analytical method to compute all of these load-carrying capacities. This analytical method is independent of the experiments and based only on the traditional R. C. and P. C. (prestressed concrete) theory. The analytical results accorded with the test results. It is suggested that this analytical method be used for analyzing and designing R. C. beams strengthened using GFRP or PGFRP sheets.展开更多
This paper aims to study the architectural design and components of Nuclear Power Plants （NPPs）. It is also focusing on the simulation system. Its main objective is to set general guidelines for architects. They sho...This paper aims to study the architectural design and components of Nuclear Power Plants （NPPs）. It is also focusing on the simulation system. Its main objective is to set general guidelines for architects. They should be aware of the basics of nuclear facilities designs and components. A traditional nuclear power plant consists of a nuclear reactor, a control building, a turbines building, cooling towers, service buildings （an office building ＆ a medical research center） and a nuclear ＆ radiation waste storage building. Bushehr nuclear power plant in Iran and Angra nuclear power plant in Brazil have been chosen as examples. Furthermore, this paper presents design analyses for Bushehr nuclear power plant and Angra nuclear power plant that include design theory （linear design and radial design） and positive ＆ negative aspects of these designs. At the end of this paper, results and recommendations on the architectural and urban aspects of nuclear power plants are revealed.展开更多
A simple and highly accurate semi-analytical method, called the differential transformation method(DTM), was used for solving the nonlinear temperature distribution equation in solid and porous longitudinal fin with t...A simple and highly accurate semi-analytical method, called the differential transformation method(DTM), was used for solving the nonlinear temperature distribution equation in solid and porous longitudinal fin with temperature dependent internal heat generation. The problem was solved for two main cases. In the first case, heat generation was assumed variable by fin temperature for a solid fin and in second heat generation varied with temperature for a porous fin. Results are presented for the temperature distribution for a range of values of parameters appearing in the mathematical formulation(e.g. N, εG, and G). Results reveal that DTM is very effective and convenient. Also, it is found that this method can achieve more suitable results in comparison to numerical methods.展开更多
In this paper the analytical performance of the low-powered Ar microwave plasma torch atomic emission spectrometry(MPT-AES) was studied.The experimental results indicate that the analytical performance of low-powered ...In this paper the analytical performance of the low-powered Ar microwave plasma torch atomic emission spectrometry(MPT-AES) was studied.The experimental results indicate that the analytical performance of low-powered ArMPT-AES is satisfactory.展开更多
A higher-order boundary element method(HOBEM)incorporated with analytical panel integrals related to translat-ing-pulsating source Green’s function is proposed for the hydrodynamic response prediction of ships advanc...A higher-order boundary element method(HOBEM)incorporated with analytical panel integrals related to translat-ing-pulsating source Green’s function is proposed for the hydrodynamic response prediction of ships advancing in waves.In this method,the 9-node bi-quadratic curvilinear elements employed to discretize the mixed-source/dipole boundary integral equation are mapped into the parametric plane through a coordinate transformation.Then in order to ease the numerical instability problem,a novel analytical quadrature is derived to calculate the influence coefficients by changing the integral order and using integration by parts.The singularity caused by infinite discontinuity is analyzed and eliminated by adopting some mathematical techniques.Through the calculations of panel integrals of Green’s function and its x-derivative,the analytical integral method is proved to be always accurate even for field points approaching the free surface,where numerical quadrature is impossible to give reasonable results.Based on this,a higher-order seakeeping program is developed and applied in the motion response prediction of two different types of ships(i.e.,a wall-sided ship Wigley III and a non-wall-sided ship S175).By comparing the computed results with the corresponding experimental data and numerical solutions of the translating-pulsating and higher-order Green’s function methods based on traditional Gauss quadrature,it is found that the HOBEM based on analytical quadrature is of better accuracy and stability.For the non-wall-sided ship,only the present method can produce reasonable pre-diction of motion responses,while obvious oscillatory phenomenon is observed in the results of the other two numerical methods based on Gauss quadrature.展开更多
Corrosion is a pervasive phenomenon affecting materials across a multitude of scales,from the atomic to the macroscopic.This review paper presents a comprehensive examination of the methodologies employed in the analy...Corrosion is a pervasive phenomenon affecting materials across a multitude of scales,from the atomic to the macroscopic.This review paper presents a comprehensive examination of the methodologies employed in the analysis of magnesium corrosion,including electrochemical,non-electrochemical and analytical approaches,emphasizing the need for a diverse array of analytical tools to understand the complex interplay between corrosion,microstructure,and the dissolution mechanisms of magnesium alloys.The research showcases the utility of specific tools like SEM/EDS and SKPFM for targeted site analysis,while XPS and FTIR provide a broader perspective on specimen surfaces.The paper also discusses the value of in-situ analysis techniques,which allow for the real-time observation of corrosion processes,offering a dynamic view of the emergence and evolution of corrosion products.These in-situ methods stand in contrast to ex-situ analyses,which only permit post-experimental evaluation.By highlighting the capabilities of various analytical tools,from those that reveal surface layer details to those that probe deeper structures,and from those that detect primary elements to those that trace minute quantities of impurities,this study underscores the intricate nature of corrosion and the critical role of advanced analytical techniques in fostering a deeper understanding of material degradation.The findings advocate for the increased application of in-situ analysis in magnesium corrosion research,as it provides a more immediate and accurate depiction of corrosion dynamics,potentially leading to more effective corrosion prevention and control strategies.展开更多
基金supported by grants from the National High Level Hospital Clinical Research Funding(2022-PUMCH-B-074)Peking Union Medical College Hospital Research Funding for Postdoc(kyfyjj202320).
文摘Objective Blood culture remains the gold standard for diagnosing bloodstream infections.Clinical laboratories must ensure the quality of blood culture processes from receipt to obtaining definitive results.We examined laboratory analytical indicators associated with positive blood culture results.Methods Blood cultures collected from Peking Union Medical College Hospital between January 1,2020,and December 31,2022,were retrospectively analyzed.The mode of transportation(piping logistics delivery vs.staff),source of blood cultures(outpatient/emergency department vs.inpatient department),rotation of personnel,and time of reception(8:00–19:59 vs.20:00–07:59)were compared between blood culture-positive and-negative results.Results Between 2020 and 2022,the total positive rate of blood culture was 8.07%.The positive rate of blood cultures in the outpatient/emergency department was significantly higher than that in the inpatient department(12.46%vs.5.83%;P<0.0001).The time-to-detection of blood cultures was significantly affected by the delivery mode and personnel rotation.The blood culture positive rate of the total pre-analytical time within 1 h was significantly higher than that within 1–2 h or>2 h(P<0.0170).Conclusion Laboratory analytical indicators such as patient source,transportation mode,and personnel rotation significantly impacted the positive detection rate or time of blood culture.
文摘BACKGROUND Gastrointestinal endoscopy technology has significantly improved the diagnostic accuracy and the successful treatment of gastrointestinal diseases.However,a series of ethical issues have emerged,such as expanding treatment indications,which affect the fair distribution of medical resources.There is limited research on ethical issues in the field of digestive endoscopy.AIM To investigate the level of ethical awareness among gastrointestinal endoscopy practitioners and analyze the ethical issues involved in gastrointestinal endoscopy technology.METHODS A questionnaire survey was performed to collect relevant data(gender,age,degree of education,professional title,personnel category,the level of understanding medical ethical principles,ethics training and its learning pathways)from gastrointestinal endoscopy practitioners at the Second Hospital of Dalian Medical University and Dalian Friendship Hospital,including licensed physicians and nurses(including trainees and graduate students).RESULTS The majority of gastrointestinal endoscopy practitioners have received training on ethics,but there is still considerable room for improvement in their ethical awareness.Different learning pathways may affect the mastery of ethical principles, and understanding of ethical principles is more easily achieved through hospital ethics institutions.CONCLUSIONTo address the ethical issues in gastrointestinal endoscopy technology, it is necessary to enhance the humanisticeducation of gastrointestinal endoscopy practitioners, incorporate ethical standards into the technology assessmentprocess, and establish a patient-centered diagnostic and treatment model to improve the ethical awareness of practitionersand achieve a balance between technology and ethics.
基金supported by the National Social Science Fund of China(NSSFC):NSSFC Major Project“Exploration and Practice in the Development of Chinese Economics Since the Modern Era”(Grant No.17ZDA034)NSSFC Key Project“The Status and Value of Traditional Chinese Economic Thought”(Grant No.17AJL006)NSSFC General Project“The Transformation and Evolution of Chinese Economic Thought During the Republican Era”(Grant No.22BJL130).
文摘Does traditional Chinese economic thought possess genuine analytical rigor?This question lies at the heart of any serious evaluation of its theoretical value and historical significance.It also matters for understanding how best to preserve,build on its remarkable achievements,and develop its intellectual legacy.Critics such as Schumpeter and Taylor have long argued that the economic reasoning found in ancient China cannot compare with that of classical Greece or medieval Europe.Yet this view often reflects the narrow assumptions of mainstream economics,defining analysis almost entirely in terms of market exchange.As a result,it tends to overlook traditions built around statecraft,governance,and the management of economic order.A careful re-examination and Sino-Western comparative analysis of key thinkers-including Mencius,Guanzi,and Sima Qian-tells a different story.Rooted in China’s distinctive cultural and philosophical heritage,traditional Chinese economic thought not only contains the analytical dimensions(as defined by Schumpeter)but also displays a broader and more diverse set of economic reasoning.Notably,its systematic depth and intellectual precision were,in many respects,remarkably advanced.Therefore,advancing the construction of a Chinese school of economics in the new era under the framework of the“Second Integration”,i.e.,integrating the basic tenets of Marxism with China’s fine traditional culture,should,and indeed can draw essential insights from this analytical tradition.
基金supported by the High-level Talents Introduction Plan from Central South University(No.502045003)the National Natural Science Foundation of China(No.42277438)Hunan Provincial Natural Science Foundation for Distinguished Young Scholars(No.2024JJ2082)to Fang Xiao,and the Postgraduate Independent Exploration and Innovation Project of Central South University,China(Nos.2024ZZTS0557 and 2023ZZTS0993)。
文摘Existing evidence suggests residential greenness is beneficial to human,while no research to date explored the associations of greenness with age-related macular degeneration(AMD).To evaluate the association of greenness with AMD,modification and mediation effect of air pollution,we conducted this prospective study.We con-structed weighted quantile sum(WQS)index as co-exposure to nitrogen oxides(NO_(x)),particulate matter<2.5μm(PM_(2.5)),particulate matter<10μm(PM10).Stratified Cox regression models were applied to test the effect of exposure.Effect modification of air pollution was assessed.Stratified Cox models through the indirect method and Aalen additive risk models were used in mediation analysis.Over median follow-up of 11.67 years,4596 AMD events were ascertained.Hazard ratios(HRs)and 95%confidence intervals(95%CIs)of incident AMD for pollution per interquartile range(IQR)increment were 1.10(1.04–1.16)for nitrogen dioxide(NO_(2)),1.09(1.03–1.15)for NO_(x),1.14(1.05–1.24)for PM_(2.5),1.13(1.05–1.21)for PM10.The HR(95%CI)of AMD associated with greenness 1000 m buffer per IQR increment was 0.91(0.86–0.97),300 m buffer was 0.94(0.89–0.99).The as-sociation between greenness 1000 m and AMD was 28.59%,44.77%,35.59%,32.31%and 27.08%mediated by the decreased WQS index,NO_(2),NO_(x),PM_(2.5) and PM10,respectively.Increased greenness was associated with lower AMD incidence,and air pollution partly mediate it,which implies that interventions aimed at improving air quality and increasing greenness could have a dual benefit in mitigating AMD risk.
文摘Background:Despite highly effective vaccines against SARS-CoV-2,COVID-19 vaccine hesitancy persisted in some populations in England during the pandemic,with rates and motivations for hesitancy varying by demographic group.Addressing the drivers of vaccine hesitancy through targeted interventions in hesitant groups is a public health priority for better and more rapid control of disease spread.We aimed to characterise the determinants and subtypes of vaccine hesitancy and identify more persistent forms of hesitancy via analysis of vaccine uptake in a large cross-sectional cohort with linked National Health Service(NHS)data.
基金financial support fromthe Chung Shan Medical University Hospital,Taiwan(CSH-2022-A-009).
文摘Background:To determine whether initiating a glucagon-like peptide-1 receptor agonist(GLP-1 RA)within 3 months of type 2 diabetes(T2DM)diagnosis alters the subsequent risk of overall and site-specific cancer and whether this association differs by baseline body-mass index(BMI).Methods:This retrospective cohort study used electronic health records from the TriNetX U.S.research network.Adults aged 20 years or older diagnosed with T2DM between 2016 and 2024 were included if they received any hypoglycemic agents within 3 months before and after diagnosis.Following 1:1 propensity score matching,both the GLP-1 RA user and non-user groups included 183,264 patients.The study outcome was defined as a diagnosis of malignant neoplasms.Hazard ratios(HRs)for overall and site-specific cancer risk were estimated using Cox proportional hazards models.Kaplan–Meier analysis and stratified analysis by BMI were performed.Results:Early GLP-1 RA use demonstrated a modest but significant association with reduced overall cancer risk(HR 0.93;95%CI:0.90–0.96).Reduced risks were noted for cancers of the digestive(HR 0.81),respiratory(HR 0.66),and female genital(HR 0.87)systems.In stratified analysis,benefits were more pronounced in patients with BMI≥30,particularly for pancreatic and colorectal cancers.Conclusion:Early initiation of GLP-1 receptor agonists in patients with diagnosed T2DM was associated with a modest reduction in overall cancer risk,particularly among individuals with obesity.These findings highlight the dual metabolic and oncologic value of prompt GLP-1 RA therapy.
基金supported by the National Natural Science Foundation of China (Nos. 51574243 and 51904302)the Yue Qi Distinguished Scholar Project of China (No. 800015Z1138)+1 种基金China University of Mining and Technology, Beijingthe Fundamental Research Funds for the Central Universities, China (No.800015J6)。
文摘Fully grouted rock bolts have been used in mining industry for many years.Much research has been conducted to evaluate the load transfer behavior of fully grouted rock bolts with experimental programs.However,compared with that,less work has been conducted with analytical modelling.Therefore,in this paper,the authors used an analytical model to study the load transfer behavior of fully grouted rock bolts.To confirm the credibility of this analytical model,an in-situ pull-out test was used to validate this model.There was a close match between the experimental result and the analytical result.Following it,a parametric study was conducted with this analytical model.The influence of coefficients,Young’s modulus of the rock bolt and the diameter of the rock bolt on the load transfer performance of rock bolts was studied.Furthermore,the load distribution along the fully grouted rock bolt was analytically studied.The results show that the axial load in the rock bolt decayed from the loaded end to the free end independent of the pull-out load.However,the trend of the load distribution curve was influenced by the pull-out load.This paper was beneficial for better understanding the load transfer mechanism of fully grouted rock bolts.
基金supported by the National Natural Science Foundation of China (Grant No.50539070)the Major State Basic Research Development Program of China (Grant No.2006CB403304)
文摘This paper presents an analytical investigation of water hammer in a hydraulic pressurized pipe system with a throttled surge chamber located at the junction between a tunnel and a penstock, and a valve positioned at the downstream end of the penstock. Analytical formulas of maximum water hammer pressures at the downstream end of the tunnel and the valve were derived for a system subjected to linear and slow valve closure. The analytical results were then compared with numerical ones obtained using the method of characteristics. There is agreement between them. The formulas can be applied to estimating water hammer pressure at the valve and transmission of water hammer pressure through the surge chamber at the junction for a hydraulic pipe system with a surge chamber.
文摘In this paper,an analytical model that represents the streamwise velocity distribution for open channel flow with submerged flexible vegetation is studied.In the present vegetated flow modelling,the whole flow field has been separated into two layers vertically: a vegetated layer and a non-vegetated free-water layer.Within the vegetated layer,an analysis of the mechanisms affecting water flow through flexible vegetation has been conducted.In the non-vegetated layer,a modified log-law equation that represents the velocity profile varying with vegetation height has been investigated.Based on the studied analytical model,a sensitivity analysis has been conducted to assess the influences of the drag (CD) and friction (Cf ) coefficients on the flow velocity.The investigated ranges of CD and Cf have also been compared to published values.The findings suggest that the CD and Cf values are non-constant at different depths and vegetation densities,unlike the constant values commonly suggested in literature.This phenomenon is particularly clear for flows with flexible vegetation,which is characterised by large deflection.
基金Project supported by the National Natural Science Foundation of China(Nos.51008017 and 51378001)the Research Fund for Beijing Postdoctoral Work,and the Innovation Fund for PhD of Beijing Jiaotong University(No.2011YJS261),China
文摘A closed-form out-of-plane dynamic displacement response of a curved track subjected to moving loads was proposed.The track structure was modeled as a planar curved Timoshenko beam periodically supported by the double-layer spring-damping elements.The general dynamic displacement response induced by the moving loads along the curve on the elastic semi-infinite space was firstly obtained in the frequency domain,according to the Duhamel integral and the dynamic reciprocity theorem.In the case of the periodic curved track structure subjected to moving loads,the dynamic displacement equation was simplified into a form of summation within the basic track cell instead of the integral.The transfer function for the curved track was expressed in the form of a transfer matrix.Single and series moving loads were involved in the calculation program.For the verification of the analytical model,the mid-span vertical deflection of a simply support curved beam subjected to moving load was recalculated and compared with the same case in the reference.The research results indicate that:under the same moving loads,the displacement response of the curved track decreases slightly with the increasing track radius,and the displacement response of the curved track with the radius greater than or equal to 600 m is almost equivalent to the displacement response of the straight track;the frequency spectrum of the curved track is more abundant than that of the straight track,which may result in more wheel-rail resonance and rail corrugation in the curved lines.
文摘The homogeneous balance method was improved and applied to two systems Of nonlinear evolution equations. As a result, several families of exact analytic solutions are derived by some new ansatzs. These solutions contain Wang's and Zhang's results and other new types of analytical solutions, such as rational fraction solutions and periodic solutions. The way can also be applied to solve more nonlinear partial differential equations.
文摘In this paper, the magneto hydrodynamic (MHD) flow of viscous fluid in a channel with non-parallel plates is studied. The governing partial differential equation was transformed into a system of dimensionless non-similar coupled ordinary differential equation. The transformed conservations equations were solved by using new algorithm. Basically, this new algorithm depends mainly on the Taylor expansion application with the coefficients of power series resulting from integrating the order differential equation. Results obtained from new algorithm are compared with the results of numerical Range-Kutta fourth-order algorithm with help of the shooting algorithm. The comparison revealed that the resulting solutions were excellent agreement. Thermo-diffusion and diffusion-thermo effects were investigated to analyze the behavior of temperature and concentration profile. Also the influences of the first order chemical reaction and the rate of mass and heat transfer were studied. The computed analytical solution result for the velocity, temperature and concentration distribution with the effect of various important dimensionless parameters was analyzed and discussed graphically.
基金China Scholarship Council(CSC)The University of Queensland for a Ph D fellowship。
文摘The long-term stability of the roof is particularly important in designing underground rock structures.To estimate the durability of roof strata in underground excavation,a computation scheme of subcritical crack growth is proposed in this study.By adopting the proposed method,the potential collapse location of strata is derivable in accordance with a static model,the durability of roof strata can be estimated,a dynamic time step control strategy is achieved to balance the accuracy and speed of computing,and the initial crack size of rock can be estimated.In addition to the above,a mechanical model of underground excavation with non-uniformly distributed loads and partially yielded foundation is presented as the prototypical case.A set of case studies is carried out that showcase a power correlation between applied stress and roof durability.The allowable applied tensile stress for a 100-year life cycle is about 76%of the tensile strength.By using the proposed subcritical crack growth computation scheme,the roof stability in an underground excavation can be identified not only from the spatial view but also from the temporal perspective.
文摘In the present scenario,tapping the unutilised hydropower potential is one of the highest priorities in developing countries of the world.Special emphasis is being imparted to run of the river(RoR)mode of power generation.However,the governments are now facing the dilemma whether to promote small hydropower projects(SHPs) or encourage large hydropower projects(LHPs).RoR large hydropower projects result into large scale cutting of mountains for constructing tunnels and access roads,generation of huge quantity of muck and large scale impact on flora and fauna due to diversion of rivers/streams.On the other hand,though SHPs are claimed to be greener and more sustainable by a section of researchers and energy planners but,they will be required to be set up in large number to generate equivalent amount of electricity.The aim of this study is to rank the most sustainable installed capacity range of RoR hydropower projects.To achieve this aim,the study proposes the use of quite popular multi-criteria decision making(MCDM)method of Operation Research named Analytical Hierarchy Process.A case study has been presented from Himachal Pradesh,a hydro rich state located in the western Himalayan region.As per sustainability assessment carried out in this study,hydropower projects in the capacity range 1 to 5 MW have been ranked to be the most sustainable.
文摘Strengthening reinforced concrete (R. C.) beams using prestressed glass fiber-reinforced polymer (PGFRP) was studied experimentally as described in Part I of this paper (Huang et al., 2005). In that paper, R. C. beams, R. C. beams with GFRP (glass fiber-reinforced polymer) sheets, and R. C. beams with PGFRP sheets were tested in both under-strengthened and over-strengthened cases. The test results showed that the load-carrying capacities (ultimate loads) of the beams with GFRP sheets were greater than those of the beams without polymer sheets. The load-carrying capacities of beams with PGFRP sheets were greater than those of beams with GFRP sheets. The objective of this work is to develop an analytical method to compute all of these load-carrying capacities. This analytical method is independent of the experiments and based only on the traditional R. C. and P. C. (prestressed concrete) theory. The analytical results accorded with the test results. It is suggested that this analytical method be used for analyzing and designing R. C. beams strengthened using GFRP or PGFRP sheets.
文摘This paper aims to study the architectural design and components of Nuclear Power Plants （NPPs）. It is also focusing on the simulation system. Its main objective is to set general guidelines for architects. They should be aware of the basics of nuclear facilities designs and components. A traditional nuclear power plant consists of a nuclear reactor, a control building, a turbines building, cooling towers, service buildings （an office building ＆ a medical research center） and a nuclear ＆ radiation waste storage building. Bushehr nuclear power plant in Iran and Angra nuclear power plant in Brazil have been chosen as examples. Furthermore, this paper presents design analyses for Bushehr nuclear power plant and Angra nuclear power plant that include design theory （linear design and radial design） and positive ＆ negative aspects of these designs. At the end of this paper, results and recommendations on the architectural and urban aspects of nuclear power plants are revealed.
文摘A simple and highly accurate semi-analytical method, called the differential transformation method(DTM), was used for solving the nonlinear temperature distribution equation in solid and porous longitudinal fin with temperature dependent internal heat generation. The problem was solved for two main cases. In the first case, heat generation was assumed variable by fin temperature for a solid fin and in second heat generation varied with temperature for a porous fin. Results are presented for the temperature distribution for a range of values of parameters appearing in the mathematical formulation(e.g. N, εG, and G). Results reveal that DTM is very effective and convenient. Also, it is found that this method can achieve more suitable results in comparison to numerical methods.
文摘In this paper the analytical performance of the low-powered Ar microwave plasma torch atomic emission spectrometry(MPT-AES) was studied.The experimental results indicate that the analytical performance of low-powered ArMPT-AES is satisfactory.
基金financially supported by the National Natural Science Foundation of China (Grant No. 52101357)the Natural Science Foundation of the Jiangsu Higher Education Institutions of China (Grant No. 21KJB580012)the Scientific Research Start-up Fund of Jiangsu University of Science and Technology
文摘A higher-order boundary element method(HOBEM)incorporated with analytical panel integrals related to translat-ing-pulsating source Green’s function is proposed for the hydrodynamic response prediction of ships advancing in waves.In this method,the 9-node bi-quadratic curvilinear elements employed to discretize the mixed-source/dipole boundary integral equation are mapped into the parametric plane through a coordinate transformation.Then in order to ease the numerical instability problem,a novel analytical quadrature is derived to calculate the influence coefficients by changing the integral order and using integration by parts.The singularity caused by infinite discontinuity is analyzed and eliminated by adopting some mathematical techniques.Through the calculations of panel integrals of Green’s function and its x-derivative,the analytical integral method is proved to be always accurate even for field points approaching the free surface,where numerical quadrature is impossible to give reasonable results.Based on this,a higher-order seakeeping program is developed and applied in the motion response prediction of two different types of ships(i.e.,a wall-sided ship Wigley III and a non-wall-sided ship S175).By comparing the computed results with the corresponding experimental data and numerical solutions of the translating-pulsating and higher-order Green’s function methods based on traditional Gauss quadrature,it is found that the HOBEM based on analytical quadrature is of better accuracy and stability.For the non-wall-sided ship,only the present method can produce reasonable pre-diction of motion responses,while obvious oscillatory phenomenon is observed in the results of the other two numerical methods based on Gauss quadrature.
文摘Corrosion is a pervasive phenomenon affecting materials across a multitude of scales,from the atomic to the macroscopic.This review paper presents a comprehensive examination of the methodologies employed in the analysis of magnesium corrosion,including electrochemical,non-electrochemical and analytical approaches,emphasizing the need for a diverse array of analytical tools to understand the complex interplay between corrosion,microstructure,and the dissolution mechanisms of magnesium alloys.The research showcases the utility of specific tools like SEM/EDS and SKPFM for targeted site analysis,while XPS and FTIR provide a broader perspective on specimen surfaces.The paper also discusses the value of in-situ analysis techniques,which allow for the real-time observation of corrosion processes,offering a dynamic view of the emergence and evolution of corrosion products.These in-situ methods stand in contrast to ex-situ analyses,which only permit post-experimental evaluation.By highlighting the capabilities of various analytical tools,from those that reveal surface layer details to those that probe deeper structures,and from those that detect primary elements to those that trace minute quantities of impurities,this study underscores the intricate nature of corrosion and the critical role of advanced analytical techniques in fostering a deeper understanding of material degradation.The findings advocate for the increased application of in-situ analysis in magnesium corrosion research,as it provides a more immediate and accurate depiction of corrosion dynamics,potentially leading to more effective corrosion prevention and control strategies.
