Primary ciliary dyskinesia(PCD)is characterized by early onset year-round wet cough,early onset year-round nasal congestion,unexplained neonatal respiratory distress,and laterality defects[1,2].There is no single"...Primary ciliary dyskinesia(PCD)is characterized by early onset year-round wet cough,early onset year-round nasal congestion,unexplained neonatal respiratory distress,and laterality defects[1,2].There is no single"gold standard"test for the diagnosis of PCD,and a diagnosis is usually made via a composite reference standard that includes clinical features,nasal nitric oxide(nNO),high-speed video microscopy(HSVM),transmission electron microscopy(TEM),and genetic analysis.Early diagnosis is imperative,as lung function can be preserved to a greater extent if patients are diagnosed earlier and appropriate treatment is initiated[3].展开更多
基金funded by Department of Biotechnology(DBT),New Delhi and Indian Council of Medical Research(ICMR),New Delhi,with Sanction No.BT/PR26396/MED/12/790/2017 and 5/7/1583/2017-RCH,respectively.
文摘Primary ciliary dyskinesia(PCD)is characterized by early onset year-round wet cough,early onset year-round nasal congestion,unexplained neonatal respiratory distress,and laterality defects[1,2].There is no single"gold standard"test for the diagnosis of PCD,and a diagnosis is usually made via a composite reference standard that includes clinical features,nasal nitric oxide(nNO),high-speed video microscopy(HSVM),transmission electron microscopy(TEM),and genetic analysis.Early diagnosis is imperative,as lung function can be preserved to a greater extent if patients are diagnosed earlier and appropriate treatment is initiated[3].
