Under the digital economy background and“dual-carbon”goals,digital transformation is a critical approach for companies to reach a high-quality development.This study analyzes the relationship between digital transfo...Under the digital economy background and“dual-carbon”goals,digital transformation is a critical approach for companies to reach a high-quality development.This study analyzes the relationship between digital transformation and corporate Environmental,Social,and Governance(ESG)performance,using digital transformation decision-making data extracted via Python text analysis.A fixed-effects model is utilized to examine if there is a postive effect between corporate digital transformation and ESG performance with panel data from China’s A-share listed companies from 2013 to 2021,including its mechanisms and pathways.Although a few research have revealed the active relationship in this field,the validity of data source is from Bloomberg more,but less from Huazheng database which is specialised for Chinese enterprises.The research yields the following findings:Firstly,digital transformation in listed companies significantly enhances ESG performance and the conclusions remain valid after conducting robust tests including variable substitution.Secondly,digital transformation enhances corporate ESG performance by easing financing constraints and boosting innovation capabilities.Thirdly,state-owned enterprise and large corporations both exert positive pronounced effects.These findings are conducive for managers to better decision-making.展开更多
Global developmental delay/intellectual disability(GDD/ID)with a prevalence of 1%e3%represents one of the biggest medical and social challenges in our society.^(1)Genetic factors are the main causes of GDD/ID and earl...Global developmental delay/intellectual disability(GDD/ID)with a prevalence of 1%e3%represents one of the biggest medical and social challenges in our society.^(1)Genetic factors are the main causes of GDD/ID and early diagnosis is crucial to improving the prognosis of GDD/ID children.^(2)Chromosomal microarray analysis,as a first-tier clinical test,^(3)remains limited because of the insufficient to detect small variations while whole exome sequencing(WES)can detect both single-nucleotide variants(SNVs)and copy-number variants(CNVs),effectively improving the diagnostic yield of GDD/ID.展开更多
In November 2024,there was an unusual surge in human metapneumovirus(hMPV)infection cases in Beijing.We performed an epidemiological investigation among cases with acute respiratory tract infection(ARTI).We enrolled A...In November 2024,there was an unusual surge in human metapneumovirus(hMPV)infection cases in Beijing.We performed an epidemiological investigation among cases with acute respiratory tract infection(ARTI).We enrolled ARTI cases from 35 sentinel hospitals,collected samples and medical records,conducted comprehensive pathogen testing,sequenced target genes or whole genomes,and performed phylogenetic analysis.A total of 79,793 cases were included in this study from 2014 to 2024.The hMPV epidemic exhibited typical seasonality from December to April of the following year,with an overall positivity rate of hMPV of 1.6%.The positivity rate of hMPV was highest in the 0–4 year age group(3.4%)and remained relatively high(1.2%)among populations over 60 years of age.Genotypes A and B were cocirculated,with predominant genotypes alternating every two years.We identified two variants of A2c with 180 or 111 nucleotide duplications in the G gene since 2016,and the A2c_(111nt-dup)has been predominant(56.9%)over the parent A2c since 2018.HMPV infection experienced an unusual surge beginning in November 2024 and peaked in December(9.5%).Subgenotype B2(98.3%)returned to the predominant position instead of the A2c_(111nt-dup)and seemed to be associated with milder illness.Twenty hMPV isolates collected in 2024 were identified as known subgenotypes(A2c and B2)via whole-genome analyses.In conclusion,hMPV exhibited a typical seasonality in Beijing,with the predominant genotypes alternating every two years.Its unusual surge in November 2024 was attributed to the reoccurrence of hMPV B2 rather than a novel variant.展开更多
1 Introduction The Chinese Academy of Engineering(CAE)has published the annual reports of Engineering Fronts 2024[1-3].A multi round interaction method,involving iterative selection and judgment between experts and da...1 Introduction The Chinese Academy of Engineering(CAE)has published the annual reports of Engineering Fronts 2024[1-3].A multi round interaction method,involving iterative selection and judgment between experts and data,was adopted.Through the deep integration of expert review and data analysis,a total of 92 engineering research fronts and 92 engineering development fronts were selected.Among them,3 engineering research fronts and 3 engineering development fronts were identified in the field of Energy and Electrical Science and Technology.展开更多
Sparse matrix operations are widely used in computational science and engineering applications such as quantum chemistry and finite element analysis,as well as modern machine learning scenarios such as social network ...Sparse matrix operations are widely used in computational science and engineering applications such as quantum chemistry and finite element analysis,as well as modern machine learning scenarios such as social network and compressed deep neural networks.The University of California,Berkeley in the famous article‘A View of the Parallel Computing Landscape’,Asanovic et al.展开更多
基金The 2024 Annual Research Project on Jiangsu Universities Philosophy and Social Sciences(Project No.:2024SJYB1637)。
文摘Under the digital economy background and“dual-carbon”goals,digital transformation is a critical approach for companies to reach a high-quality development.This study analyzes the relationship between digital transformation and corporate Environmental,Social,and Governance(ESG)performance,using digital transformation decision-making data extracted via Python text analysis.A fixed-effects model is utilized to examine if there is a postive effect between corporate digital transformation and ESG performance with panel data from China’s A-share listed companies from 2013 to 2021,including its mechanisms and pathways.Although a few research have revealed the active relationship in this field,the validity of data source is from Bloomberg more,but less from Huazheng database which is specialised for Chinese enterprises.The research yields the following findings:Firstly,digital transformation in listed companies significantly enhances ESG performance and the conclusions remain valid after conducting robust tests including variable substitution.Secondly,digital transformation enhances corporate ESG performance by easing financing constraints and boosting innovation capabilities.Thirdly,state-owned enterprise and large corporations both exert positive pronounced effects.These findings are conducive for managers to better decision-making.
基金supported by the Shanghai Municipal Commission of Science and Technology Research Project(China)(No.19JC1411001)the National Key Research and Development Program from the Ministry of Science and Technology of the People’s Republic of China(No.2021YFC2700800)+4 种基金the National Natural Science Foundation of China(No.31972880,32170615,31611130035,31371274)the National Key Research and Development Plan for Stem Cell and Transformation Research(China)(No.2017YFA0104202)the Collaborative Innovation Center Project Construction for Shanghai Women and Children’s Health,the Open Research Fund of National Health Commission Key Laboratory of Birth Defects Prevention&Henan Key Laboratory of Population Defects Prevention(China)(No.ZD202309)The Medical Science and Technology Research Program Project of Henan Province,China(No.LHGJ20230368)the Postdoctoral Research Fund of the Third Affiliated Hospital of Zhengzhou University(No.BSH20230101).
文摘Global developmental delay/intellectual disability(GDD/ID)with a prevalence of 1%e3%represents one of the biggest medical and social challenges in our society.^(1)Genetic factors are the main causes of GDD/ID and early diagnosis is crucial to improving the prognosis of GDD/ID children.^(2)Chromosomal microarray analysis,as a first-tier clinical test,^(3)remains limited because of the insufficient to detect small variations while whole exome sequencing(WES)can detect both single-nucleotide variants(SNVs)and copy-number variants(CNVs),effectively improving the diagnostic yield of GDD/ID.
基金the Beijing Municipal Health Commission’s Funds for the High-qualified Public Health Professionals Development Project(Leading Professionals-01-10)Capital’s Funds for Health Improvement and Research(2024-1G-3015)Beijing Natural Science Foundation(L242051).
文摘In November 2024,there was an unusual surge in human metapneumovirus(hMPV)infection cases in Beijing.We performed an epidemiological investigation among cases with acute respiratory tract infection(ARTI).We enrolled ARTI cases from 35 sentinel hospitals,collected samples and medical records,conducted comprehensive pathogen testing,sequenced target genes or whole genomes,and performed phylogenetic analysis.A total of 79,793 cases were included in this study from 2014 to 2024.The hMPV epidemic exhibited typical seasonality from December to April of the following year,with an overall positivity rate of hMPV of 1.6%.The positivity rate of hMPV was highest in the 0–4 year age group(3.4%)and remained relatively high(1.2%)among populations over 60 years of age.Genotypes A and B were cocirculated,with predominant genotypes alternating every two years.We identified two variants of A2c with 180 or 111 nucleotide duplications in the G gene since 2016,and the A2c_(111nt-dup)has been predominant(56.9%)over the parent A2c since 2018.HMPV infection experienced an unusual surge beginning in November 2024 and peaked in December(9.5%).Subgenotype B2(98.3%)returned to the predominant position instead of the A2c_(111nt-dup)and seemed to be associated with milder illness.Twenty hMPV isolates collected in 2024 were identified as known subgenotypes(A2c and B2)via whole-genome analyses.In conclusion,hMPV exhibited a typical seasonality in Beijing,with the predominant genotypes alternating every two years.Its unusual surge in November 2024 was attributed to the reoccurrence of hMPV B2 rather than a novel variant.
基金supported by the project,“Strategic Consulting and Research of Global Engineering Fronts”of the CAE under the guidance and assistance from the project integration group.
文摘1 Introduction The Chinese Academy of Engineering(CAE)has published the annual reports of Engineering Fronts 2024[1-3].A multi round interaction method,involving iterative selection and judgment between experts and data,was adopted.Through the deep integration of expert review and data analysis,a total of 92 engineering research fronts and 92 engineering development fronts were selected.Among them,3 engineering research fronts and 3 engineering development fronts were identified in the field of Energy and Electrical Science and Technology.
文摘Sparse matrix operations are widely used in computational science and engineering applications such as quantum chemistry and finite element analysis,as well as modern machine learning scenarios such as social network and compressed deep neural networks.The University of California,Berkeley in the famous article‘A View of the Parallel Computing Landscape’,Asanovic et al.
