Purpose:This study provides a comprehensive bibliometric analysis of the environmental management control tools literature.It seeks to summarize this body of literature’s growth and identify the most influential auth...Purpose:This study provides a comprehensive bibliometric analysis of the environmental management control tools literature.It seeks to summarize this body of literature’s growth and identify the most influential authors,journals,and articles in this field.The main objective of this article is to determine which tools are most prominent in the literature.Methodology/approach:The study examined 541 articles published in 126 academically indexed journals in the Scopus database.The analyzed timeframe covers the period from 2011 to 2023.We used VOSviewer software for statistical calculations to map the collaborations among authors and journals and to develop a conceptual and intellectual map of the field.Results:Our findings show that the literature on environmental management control tools is flourishing.The authors who dominated this period are mainly Schaltegger,Sala,and Ulgiati.The Journal of Cleaner Production is the primary source of publications,with an astounding 241 documents.The United States attained the leading position in terms of publication with 86 documents,which explains its willingness to collaborate with other countries,followed by China and Australia with 70 and 66 papers,respectively.Finally,bibliometric analysis shows that“life cycle assessment”,“cost-benefit analysis”,and“sustainability reporting”are the most prominent tools in research on this topic.Originality/value:This article provides several starting points for researchers and practitioners investigating environmental management control tools.It contributes to broadening the field’s vision and then offers recommendations for future studies.展开更多
ⅡEnvironmental education is gaining increasing recognition in Morocco as a fundamental pillar for achieving the Sustainable Development Goals(SDGs).Within this context,school-based environmental clubs play a crucial ...ⅡEnvironmental education is gaining increasing recognition in Morocco as a fundamental pillar for achieving the Sustainable Development Goals(SDGs).Within this context,school-based environmental clubs play a crucial role in promoting awareness and building climate resilience among students at various educational levels.These clubs serve not only as platforms for ecological engagement but also as practical tools for embedding sustainability into everyday learning.This study explores the main factors that influence the creation,activation,and effectiveness of environmental clubs in Moroccan schools.Relying on a quantitative survey conducted with 42 respondents,including both teachers and school administrators,the research highlights several key enablers.Among the most significant are access to adequate training in environmental education,the presence of strong institutional support,and the availability of sufficient resources.The analysis uses descriptive statistics,chi-square testing,and a Weighted Average Index to better understand the relationships between these variables.Findings reveal a strong correlation between environmental training and the initiation of clubs,although this does not always translate into high levels of student engagement.The main obstacles identified include insufficient time,lack of funding,and a shortage of appropriate educational materials.In conclusion,the study emphasizes the importance of expanding training initiatives,dedicating specific time within school schedules,and improving access to materials.These steps are essential to fully integrate environmental clubs into the Moroccan educational system and to enhance their overall impact.展开更多
During times of war, it is rare to find a government willing and able to require the military to fund and support environmental impact studies. In the 1960s, many United States scientists expressed concerns about the ...During times of war, it is rare to find a government willing and able to require the military to fund and support environmental impact studies. In the 1960s, many United States scientists expressed concerns about the use of herbicides during the Vietnam War. This protest was led by Dr. Arthur Galston and eventually included scientists with the National Academy of Science. By 1970, the Department of Defense (DoD) was ordered to permit the scientists to visit South Vietnam during the war to document these impacts. In all 1500 scientist days were spent in South Vietnam. In addition, the US government and military funded research studies on the impact of herbicides on animals. The goal of military use of herbicides, as chemical weapons, was to defoliate jungle forests and destroy food crops as a strategy to win battles and the war. The primary objective of this research study is to describe how it is possible for a country to fund and carry out scientific studies during the conduct of a war rather than decades later. The environmental impact study findings often lack boots on the ground validation and can be inaccurate or misleading in some situations. The United States (US) and other countries, including Russia and Ukraine, need to learn the historical lessons from the US use of herbicides, containing dioxin TCDD and/or arsenic (As), as chemical weapons during the Vietnam War.展开更多
The purpose of this study lies in exploring the role of materiality in environmental information disclosures under the securities laws of the United States and China,discussing the differences in the regulatory mechan...The purpose of this study lies in exploring the role of materiality in environmental information disclosures under the securities laws of the United States and China,discussing the differences in the regulatory mechanism,limits of enforcement,and challenges of seeking global harmonization.The paper does a comparative legal analysis of statutory provisions,judicial interpretations,and regulatory frameworks of the U.S.Securities and Exchange Commission(SEC)and the China Securities Regulatory Commission(CSRC).Furthermore,it provides frameworks of global sustainability reporting such as the Task Force on Climate-related Financial Disclosures(TCFD)and the Global Reporting Initiative(GRI).The findings show that U.S.securities law uses a financial materiality standard with respect to what companies must disclose to investors.On the other hand,China’s regulatory approach has a double materiality in considering not only financial impacts but also wider environmental and social factors.Although there are these distinctions,both of these jurisdictions face issues of common obstruction such as ambiguities in materiality determination,inconsistent enforcement,and fear of greenwashing.This paper asserts that the U.S.and China regulatory frameworks need to converge more to promote greater corporate transparency and ESG disclosures.Regulators can even align disclosure practices with internationally recognized standards of work to add confidence for investors,fight off misleading sustainability claims and ensure accountable reporting in pertinent environments.The study concludes that the green challenges of global markets can only be tackled by regulating cooperative actions and using standardized reporting guidelines.展开更多
As emerging pollutants,microplastics have recently received considerable attention owing to detection in various organisms and environments.Mass production and widespread use of plastic products increase their potenti...As emerging pollutants,microplastics have recently received considerable attention owing to detection in various organisms and environments.Mass production and widespread use of plastic products increase their potential risks to humans owing to their persistent,mobile,and toxic properties.Numerous methods have been used to identify and quantify the various forms of microplastics,however,unified standards do not exist.In this review,we systematically summarize the sources,migration,transformation,and analytical methods for microplastics in diverse ecosystems,particularly the most recent sampling and identification techniques.Additionally,the environmental effects and health hazards of microplastics on aquatic and terrestrial systems,as well as human beings are discussed.We also present management strategies for reducing microplastics in a broader social and policy context.This review aims to provide an overview of the migration,transformation,sampling,analysis,and environmental effects of microplastics,which addresses knowledge gaps in microplastic pollution and provides proposals for key research gaps.展开更多
Urban eco-environmental management is a key focus in the modernization of national governance systems and governance capacity.Advanced information technology should be used to identify ecological problems in urban are...Urban eco-environmental management is a key focus in the modernization of national governance systems and governance capacity.Advanced information technology should be used to identify ecological problems in urban areas accurately while enhancing the environmental management capacity to promote the sustainable development of cities.This study centers on statistical data from PM_(2.5)air monitoring stations in Shenzhen,China,and supplemental data,such as population distribution data from China Unicom’s mobile phone signaling.Data cleaning and fusion are used to construct a spatial dataset of an eco-environmental problem:PM_(2.5)concentrations.The geostatistical analysis tool ArcGIS is used to identify the most suitable interpolation method for reflecting this eco-environmental problem based on multiple parameter adjustments and repeated testing.A hotspot distribution map of PM_(2.5)concentrations is generated,and correlation analysis is conducted on the population density and distribution patterns in these hotspot areas.This enables the quantitative analysis and exploration of the spatial characteristics and coupling relationships of PM_(2.5)concentrations.The results show a positive correlation between the PM_(2.5)concentration distribution and the points of interest,road network density,number of dead-end roads,and average building height in Shenzhen.No correlation is found between population and building densities and the PM_(2.5)concentration distribution,possibly due to the city’s effective environmental management and pollution control measures.These findings help advance the development of precise,scientific,legally compliant pollution control strategies and decision-making processes.Furthermore,they provide technical support for urban eco-environmental planning,management,and sustainable development.展开更多
This study assesses the potential and benefits of reducing plastic consumption at the institutional level by taking the Beijing Institute of Petrochemical Technology(BIPT)in China as the case.By tracking the plastic m...This study assesses the potential and benefits of reducing plastic consumption at the institutional level by taking the Beijing Institute of Petrochemical Technology(BIPT)in China as the case.By tracking the plastic material flow on the BIPT campus,we provide insights into the efforts required to achieve a plastic-free campus.A mixed-methods approach was employed,encompassing material flow analysis,quantitative analysis of influencing factors,examination of best practices in universities,and market price-based valuation of plastic reduction.The main conclusions are as follows:(1)Each student consumed an average of 9.2 kg of plastics for daily use on BIPT campus in the base year of 2020,with campus canteens,off-campus cafés,and shops(offline and online)contributing to 36%,31%and 30%respectively.(2)BIPT has a reduction potential of 45%,equivalent to 4.1 kg per student annually,yielding benefits of 45 RMB from savings in oil material and production energy,avoiding plastic waste,and reducing carbon emission.(3)If all global tertiary institutions set a target of reducing plastics by 4.1 kg per student,1.94 Mt of plastics could be avoided by 2035.(4)Greater reductions and benefits could be achieved if tertiary institutions extend their efforts across all campus activities,with substantial indirect and long-term contributions ranging from more sustainable campus management to fostering a transition towards a green economy.These findings highlight that plastic-free initiatives require contextual construction and environmental education both on and off campus.展开更多
Six new lanthanide complexes:[Ln(3,4-DEOBA)3(4,4'-DM-2,2'-bipy)]2·2C_(2)H_(5)OH,[Ln=Dy(1),Eu(2),Tb(3),Sm(4),Ho(5),Gd(6);3,4-DEOBA-=3,4-diethoxybenzoate,4,4'-DM-2,2'-bipy=4,4'-dimethyl-2,2'...Six new lanthanide complexes:[Ln(3,4-DEOBA)3(4,4'-DM-2,2'-bipy)]2·2C_(2)H_(5)OH,[Ln=Dy(1),Eu(2),Tb(3),Sm(4),Ho(5),Gd(6);3,4-DEOBA-=3,4-diethoxybenzoate,4,4'-DM-2,2'-bipy=4,4'-dimethyl-2,2'-bipyridine]were successfully synthesized by the volatilization of the solution at room temperature.The crystal structures of six complexes were determined by single-crystal X-ray diffraction technology.The results showed that the complexes all have a binuclear structure,and the structures contain free ethanol molecules.Moreover,the coordination number of the central metal of each structural unit is eight.Adjacent structural units interact with each other through hydrogen bonds and further expand to form 1D chain-like and 2D planar structures.After conducting a systematic study on the luminescence properties of complexes 1-4,their emission and excitation spectra were obtained.Experimental results indicated that the fluorescence lifetimes of complexes 2 and 3 were 0.807 and 0.845 ms,respectively.The emission spectral data of complexes 1-4 were imported into the CIE chromaticity coordinate system,and their corre sponding luminescent regions cover the yellow light,red light,green light,and orange-red light bands,respectively.Within the temperature range of 299.15-1300 K,the thermal decomposition processes of the six complexes were comprehensively analyzed by using TG-DSC/FTIR/MS technology.The hypothesis of the gradual loss of ligand groups during the decomposition process was verified by detecting the escaped gas,3D infrared spectroscopy,and ion fragment information detected by mass spectrometry.The specific decomposition path is as follows:firstly,free ethanol molecules and neutral ligands are removed,and finally,acidic ligands are released;the final product is the corresponding metal oxide.CCDC:2430420,1;2430422,2;2430419,3;2430424,4;2430421,5;2430423,6.展开更多
Border-associated macrophages are located at the interface between the brain and the periphery, including the perivascular spaces, choroid plexus, and meninges. Until recently, the functions of border-associated macro...Border-associated macrophages are located at the interface between the brain and the periphery, including the perivascular spaces, choroid plexus, and meninges. Until recently, the functions of border-associated macrophages have been poorly understood and largely overlooked. However, a recent study reported that border-associated macrophages participate in stroke-induced inflammation, although many details and the underlying mechanisms remain unclear. In this study, we performed a comprehensive single-cell analysis of mouse border-associated macrophages using sequencing data obtained from the Gene Expression Omnibus(GEO) database(GSE174574 and GSE225948). Differentially expressed genes were identified, and enrichment analysis was performed to identify the transcription profile of border-associated macrophages. CellChat analysis was conducted to determine the cell communication network of border-associated macrophages. Transcription factors were predicted using the ‘pySCENIC' tool. We found that, in response to hypoxia, borderassociated macrophages underwent dynamic transcriptional changes and participated in the regulation of inflammatory-related pathways. Notably, the tumor necrosis factor pathway was activated by border-associated macrophages following ischemic stroke. The pySCENIC analysis indicated that the activity of signal transducer and activator of transcription 3(Stat3) was obviously upregulated in stroke, suggesting that Stat3 inhibition may be a promising strategy for treating border-associated macrophages-induced neuroinflammation. Finally, we constructed an animal model to investigate the effects of border-associated macrophages depletion following a stroke. Treatment with liposomes containing clodronate significantly reduced infarct volume in the animals and improved neurological scores compared with untreated animals. Taken together, our results demonstrate comprehensive changes in border-associated macrophages following a stroke, providing a theoretical basis for targeting border-associated macrophages-induced neuroinflammation in stroke treatment.展开更多
This study aimed to identify the worst“bad actors”in mixtures of pollutants contributing to liver damage and shorter telomeres in the U.S.population,using weighted quantile sum(WQS)modeling with stratification by ra...This study aimed to identify the worst“bad actors”in mixtures of pollutants contributing to liver damage and shorter telomeres in the U.S.population,using weighted quantile sum(WQS)modeling with stratification by race/ethnicity.We conducted a comprehensive cross-sectional analysis of mixtures of pollutants in National Health and Nutrition Examination Survey datasets:(1)33,979 adults with blood levels of cadmium(Cd),lead(Pb),and mercury,including subsets with measurements of per-/polyfluoroalkyl substances(PFAS),and polychlorinated biphenyls(PCBs)/polychlorinated dibenzo-p-dioxins and dibenzofurans(PCDD/Fs);and(2)7360 adults with measurements of telomeres,Cd,and Pb.Multivariable-adjusted WQS regression examined associations between WQS mixture indices and liver injury(alanine aminotransferase(ALT)-elevation),advanced liverfibrosis(LF),and telomere length.WQSmetal indices were associated with advanced-LF in all racial/ethnic groups.The top contributor was Cd in the total population and in non-Hispanic Whites(NHW),while Pb was the top contributor in non-Hispanic Blacks(NHB).The WQSmetal-PCB-PCDD/F index was associated with ALT-elevation,with PCB126,Cd and Pb as main contributors;the odds ratio(OR)per decile was 1.50(95%CI,1.26–1.78),while the OR per decile of the WQSmetal-PFAS index was 1.03(95%CI,0.98–1.05),not significant.WQS_(metal indices)were associated with shorter telomeres.Cd was main contributor associated with advanced-LF in NHW,while Pb was the major bad actor in NHB,suggesting that NHB may be especially susceptible to Pb toxicity.Metals were associated with shorter telomeres.Metal and PCB/PCDD/F mixtures were associated with ALT-elevation.Heavy metals and organic chemicals may contribute to liver-related morbidity and healthcare disparities.展开更多
Human cardiac organoids have revolutionized the study of cardiac development,disease modeling,drug discovery,and regenerative therapies.This review systematically discusses strategies and progress in the construction ...Human cardiac organoids have revolutionized the study of cardiac development,disease modeling,drug discovery,and regenerative therapies.This review systematically discusses strategies and progress in the construction of cardiac organoids,categorizing them into three main types:cardiac spheroids,self-organizing/assembloid organoids,and organoid-on-a-chip systems.This review uniquely integrates the advances in vascularization,organ-on-chip design,and environmental cardiotoxicity modeling within cardiac organoid platforms,offering a critical synthesis that is absent in the literature.In the context of escalating environmental threats to cardiovascular health,there is an urgent need for physiologically relevant models to accurately identify cardiac toxicants and elucidate their underlying mechanisms of action.This review highlights advances in cardiac organoid applications for disease modeling—including congenital heart defects and acquired cardiovascular diseases—drug development,toxicity screening,and the study of environmentally induced cardiovascular pathogenesis.In addition,it critically examines ongoing challenges and underscores opportunities brought by bioengineering approaches.Finally,we propose future directions for developing standardized cardiac organoid platforms with clinical predictability,aiming to expand the utility of this technology across broader research applications.展开更多
Environmental DNA(eDNA)technology has revolutionized biodiversity monitoring with its non-invasive,sensitive,and cost-efficient approach.This paper systematically reviews eDNA advancements,examining its applications i...Environmental DNA(eDNA)technology has revolutionized biodiversity monitoring with its non-invasive,sensitive,and cost-efficient approach.This paper systematically reviews eDNA advancements,examining its applications in aquatic and terrestrial ecosystems and assessing China’s standardization progress.It delineates four developmental phases from single-species detection to high-throughput sequencing,and highlights China’s contribution to the development of technical standards.While significant progress has been made,challenges persist in quantitative accuracy,methodological consistency,and large-scale implementation.Future efforts should prioritize enhanced standardization,improved quantification techniques,broader applications,and international collaboration to drive innovation in eDNA technology.展开更多
Background:Receptor-interacting protein kinases(RIPKs)regulate cell death,inflammation,and immune responses,yet their roles in cancer are not fully understood.This study investigates the expression,genomic alterations...Background:Receptor-interacting protein kinases(RIPKs)regulate cell death,inflammation,and immune responses,yet their roles in cancer are not fully understood.This study investigates the expression,genomic alterations,and functional implications of RIPK family members across various cancers.Methods:We collected multi-omics data from The Cancer Genome Atlas and other public databases,including gene expression,copy number variation(CNV),mutation,methylation,tumor mutation burden(TMB),and microsatellite instability(MSI).Differential expression and survival analyses were performed using DESeq2 and Cox proportional hazards models.CNV and mutation data were analyzed with GISTIC2 and Mutect2,and methylation data with the ChAMP package.Correlations with TMB and MSI were assessed using Pearson coefficients,and gene set enrichment analysis was conducted with the MSigDB Hallmark gene sets.Results:RIPK family members show significant differential expression in various cancers,with RIPK1 and RIPK4 frequently altered.Survival analysis reveals heterogeneous impacts on overall survival.CNV and mutation analyses identify high alteration frequencies for RIPK2 and RIPK7,affecting gene expression.RIPK1 and RIPK7 are hypermethylated in several cancers,inversely correlating with RIPK3 expression.RIPK1,RIPK2,RIPK5,RIPK6,and RIPK7 correlate positively with TMB,while RIPK3 shows negative correlations in some cancers.MSI analysis indicates associations with DNA mismatch repair.G ene set enrichment analysis highlights immune-related pathway enrichment for RIPK1,RIPK2,RIPK3,and RIPK6,and cell proliferation and DNA repair pathways for RIPK4 and RIPK5.RIPK family members showed heterogeneous alterations across cancers:for example,RIPK7 was mutated in up to~15%of u terine c orpus e ndometrial c arcinoma and l ung s quamous c ell c arcinoma cases,and RIPK1 and RIPK7 exhibited frequent promoter hypermethylation in multiple tumor types.Several genes displayed context-dependent associations with overall survival and with TMB/MSI.Conclusion:This pan-cancer analysis of the RIPK family reveals their diverse roles and potential as biomarkers and therapeutic targets.The findings emphasize the importance of RIPK genes in tumorigenesis and suggest context-dependent functions across cancer types.Further studies are needed to explore their mechanisms in cancer development and clinical applications.展开更多
The Loess Plateau(LP),one of the most ecologically fragile regions in China,is affected by severe soil erosion and environmental degradation.Despite large-scale ecological restoration efforts made by Chinese governmen...The Loess Plateau(LP),one of the most ecologically fragile regions in China,is affected by severe soil erosion and environmental degradation.Despite large-scale ecological restoration efforts made by Chinese government in recent years,the region continues to face significant ecological challenges due to the combined impact of climate change and human activities.In this context,we developed a kernal Remote Sensing Ecological Index(kRSEI)using Moderate Resolution Imaging Spectroradiometer(MODIS)products on the Google Earth Engine(GEE)platform to analyze the spatiotemporal patterns and trends in ecological environmental quality(EEQ)across the LP from 2000 to 2022 and project future trajectories.Then,we applied partial correlation analysis and multivariate regression residual analysis to further quantify the relative contributions of climate change and human activities to EEQ.During the study period,the kRSEI values exhibited significant spatial heterogeneity,with a stepwise degradation pattern in the southeast to northwest across the LP.The maximum(0.51)and minimum(0.46)values of the kRSEI were observed in 2007 and 2021,respectively.Trend analyses revealed a decline in EEQ across the LP.Hurst exponent analysis predicted a trend of weak anti-persistent development in most of the plateau areas in the future.A positive correlation was identified between kRSEI and precipitation,particularly in the central and western regions;although,improvements were limited by a precipitation threshold of 837.66 mm/a.A moderate increase in temperature was shown to potentially benefit the ecological environment within a certain range;however,temperature of-1.00°C-7.95°C often had a negative impact on the ecosystem.Climate change and human activities jointly influenced 65.78%of LP area on EEQ,primarily having a negative impact.In terms of contribution,human activities played a dominant role in driving changes in EEQ across the plateau.These findings provide crucial insights for accurately assessing the ecological state of the LP and suggest the design of future restoration strategies.展开更多
Global environmental changes including climate warming,extreme weather events,ambient air pollution,freshwater contamination,and landscape transformation are reshaping the epidemiology of infectious diseases with unpr...Global environmental changes including climate warming,extreme weather events,ambient air pollution,freshwater contamination,and landscape transformation are reshaping the epidemiology of infectious diseases with unprecedented complexity,particularly in the post-COVID-19 era.This review synthesizes evidence from the past decade(2015-2024)to systematically elucidate how key environmental drivers modulate pathogen emergence,transmission dynamics,and clinical outcomes,with a focus on underlying mechanistic pathways.Specifically,we highlight:(1)the temperature-and precipitation-dependent transmission of vector-borne diseases(e.g.,malaria,dengue)via expanded vector habitats and accelerated pathogen incubation;(2)the exacerbation of respiratory infections(including COVID-19)by particulate matter(PM2.5)and nitrogen dioxide(NO2)through impaired mucosal immunity and enhanced inflammatory responses;(3)the persistence of diarrheal diseases in low-and middle-income countries(LMICs)linked to water insecurity and climate-induced infrastructure failure;and(4)zoonotic spillover risks amplified by urbanization and deforestation-driven human-wildlife interface disruption.Integrating the One Health socioecological framework,we further summarize methodological advances from high-resolution genomic surveillance to climate-informed machine learning models that have improved causal inference and predictive accuracy.Our synthesis confirms that environmental factors are not merely contextual but central,modifiable determinants of infectious disease risk,with disproportionate impacts on vulnerable populations.To mitigate future threats,we emphasize the urgency of interdisciplinary collaboration,integrated environmental-health monitoring platforms,and climate-resilient public health policies tailored to post-pandemic challenges.This review provides a timely roadmap for translating environmental epidemiology insights into actionable strategies to strengthen global health resilience.展开更多
The sulfation and decomposition process has proven effective in selectively extracting lithium from lepidolite.It is essential to clarify the thermochemical behavior and kinetic parameters of decomposition reactions.A...The sulfation and decomposition process has proven effective in selectively extracting lithium from lepidolite.It is essential to clarify the thermochemical behavior and kinetic parameters of decomposition reactions.Accordingly,comprehensive kinetic study by employing thermalgravimetric analysis at various heating rates was presented in this paper.Two main weight loss regions were observed during heating.The initial region corresponded to the dehydration of crystal water,whereas the subsequent region with overlapping peaks involved complex decomposition reactions.The overlapping peaks were separated into two individual reaction peaks and the activation energy of each peak was calculated using isoconversional kinetics methods.The activation energy of peak 1 exhibited a continual increase as the reaction conversion progressed,while that of peak 2 steadily decreased.The optimal kinetic models,identified as belonging to the random nucleation and subsequent growth category,provided valuable insights into the mechanism of the decomposition reactions.Furthermore,the adjustment factor was introduced to reconstruct the kinetic mechanism models,and the reconstructed models described the kinetic mechanism model more accurately for the decomposition reactions.This study enhanced the understanding of the thermochemical behavior and kinetic parameters of the lepidolite sulfation product decomposition reactions,further providing theoretical basis for promoting the selective extraction of lithium.展开更多
Anammox bacteria in constructed wetlands(CWs)play pivotal role in sustainable nitrogen transformation,yet existing studies lack comprehensive analysis of environmental gradients and microbial interactions,both key fac...Anammox bacteria in constructed wetlands(CWs)play pivotal role in sustainable nitrogen transformation,yet existing studies lack comprehensive analysis of environmental gradients and microbial interactions,both key factors in anammox bacteria enrichment.This study investigated the mechanisms driving anammox bacteria enrichment in lab-scale simulated CWs treating high-nitrogen wastewater,focusing on bacterial community re-sponses across wetland layers with various strategies,including continuous up-flow influent,nitrogen loading increase,effluent recirculation,intermittent influent,and anammox bacteria inoculation.Results showed that total relative and absolute abundances of anammox bacteria ranged from 0.77%to 12.50%and from 0.13 to 6.46×10^(7) copies/g,respectively.Dissolved oxygen and pH had significant positive correlations with the absolute abundance of anammox bacteria,while organic matter and nitrate negatively impacted their relative abundance.Permutational multivariate analysis of variance indicated that spatial heterogeneity explained more variation in anammox bacteria abundance(43.44%)compared to operational strategies(8.58%).In terms of microbial interactions,60 dominant species exhibited potential correlations with anammox bacteria,comprising 170 interactions(105 positive and 65 negative),which suggested that anammox bacteria generally foster cooperative relationships with dominant bacteria.Notably,significant interspecies interactions were observed between Candidatus Kuenenia(dominant anammox bacteria in CWs)and species within the genera Chitinivibrio-nia and Anaerolineaceae,suggesting that microbial interactions primarily manifest as indirect facilitative effects rather than direct mutualistic relationships.Given that the Normalized Stochasticity Ratio in CWs were<50%,this study inferred that environmental gradients have greater influence on anammox bacteria than microbial interactions.展开更多
Despite the widespread presence and frequent detection of polycyclic aromatic hydrocarbons(PAHs)in various aspects of life,there is limited research on their exposure levels in pregnant women and cumulative exposure f...Despite the widespread presence and frequent detection of polycyclic aromatic hydrocarbons(PAHs)in various aspects of life,there is limited research on their exposure levels in pregnant women and cumulative exposure from the living environment.This study included 1311 women in late pregnancy from the Zunyi birth cohort and measured the urinary concentrations of 10 hydroxylated PAH metabolites(OH-PAHs).Risk assessment was conducted based on the estimated daily intake to calculate the hazard quotient and hazard index(HI).A linear regression model was used to analyze the relationship between creatinine-adjusted OH-PAHs concentrations and living environment and lifestyle factors,while principal component analysis was applied to trace the sources of PAHs exposure.1-OHPYR was detected in all participants’urine,with naphthalene metabolites having the highest concentrations among creatinine-adjusted PAHs.OH-PAHs concentrations were associated with housing type,room number,cooking frequency,household size,exercise frequency,fuel type,distance from main road,and drinking water source.Pregnant women using traditional fuels and living in bungalows had higher health risks than those using clean energy and living in buildings.Those living within 100 m of a main road had higher HI than those farther away.Coal combustion was identified as the primary source of PAHs exposure.The study emphasizes the importance of reducing PAHs exposure,especially for pregnant women living in polluted environments.It recommends public health interventions such as improving indoor ventilation and providing clean energy to reduce related health risks.展开更多
In this study,the design,analysis,manufacturing,and testing of a 3D-printed conformal microstrip array antenna for high-temperature environments is presented.3D printing technology is used to fabricate a curved cerami...In this study,the design,analysis,manufacturing,and testing of a 3D-printed conformal microstrip array antenna for high-temperature environments is presented.3D printing technology is used to fabricate a curved ceramic substrate,and laser sintering and microdroplet spraying processes are used to add the conductive metal on the curved substrate.The problems of gain loss,bandwidth reduction,and frequency shift caused by high temperatures are addressed by using a proper antenna design,with parasitic patches,slots,and metal resonant cavities.The antenna prototype is characterized by the curved substrates and the conductive metals for the power dividers,the patch,and the ground plane;its performance is examined up to a temperature of 600℃in a muffle furnace and compared with the results from the numerical analysis.The results show that the antenna can effectively function at 600℃and even higher temperatures.展开更多
AIM:To present an overview of the research on global glaucoma treatment in the last decade in terms of publication year,journals,countries/regions,organizations,references,and keywords,to investigate the current resea...AIM:To present an overview of the research on global glaucoma treatment in the last decade in terms of publication year,journals,countries/regions,organizations,references,and keywords,to investigate the current research international trends and hot topics in this area.METHODS:Bibliometric analysis was conducted on 9128 articles in the Web of Science Core Collection(WoSCC;Clarivate)database.Quantitative and qualitative analysis was employed using VOSviewer(v1.6.18),Pajek(v1.0.0.0),and CiteSpace(v6.1.R2)software.RESULTS:The 9128 papers relating to glaucoma treatment were published from April 2013 to April 2023,of which 7482 articles(82%)were original research articles and 1464(18%)were review articles.The United States(2867)and Johns Hopkins University(166)were the most productive country and institution,respectively,but the University College London had the highest h-index(54).The Journal of Glaucoma was the most productive and Ophthalmology had the highest h-index compared with other journals.The Keywords of interest included treatment surgery,cyclophotocoagulation,minimally invasive glaucoma surgery(MIGS),trabeculectomy,baerveldt,epidemiology,medication adherence,nanoparticle,optical coherence tomography(OCT),gene therapy,and artificial intelligence(AI).Glaucoma surgery appeared as a current research hotspot through the analysis of keywords.CONCLUSION:This study provides insights into the research trends and potential research hotspots in the treatment of glaucoma.This will help researchers to evaluate research policies and to promote international cooperation.展开更多
文摘Purpose:This study provides a comprehensive bibliometric analysis of the environmental management control tools literature.It seeks to summarize this body of literature’s growth and identify the most influential authors,journals,and articles in this field.The main objective of this article is to determine which tools are most prominent in the literature.Methodology/approach:The study examined 541 articles published in 126 academically indexed journals in the Scopus database.The analyzed timeframe covers the period from 2011 to 2023.We used VOSviewer software for statistical calculations to map the collaborations among authors and journals and to develop a conceptual and intellectual map of the field.Results:Our findings show that the literature on environmental management control tools is flourishing.The authors who dominated this period are mainly Schaltegger,Sala,and Ulgiati.The Journal of Cleaner Production is the primary source of publications,with an astounding 241 documents.The United States attained the leading position in terms of publication with 86 documents,which explains its willingness to collaborate with other countries,followed by China and Australia with 70 and 66 papers,respectively.Finally,bibliometric analysis shows that“life cycle assessment”,“cost-benefit analysis”,and“sustainability reporting”are the most prominent tools in research on this topic.Originality/value:This article provides several starting points for researchers and practitioners investigating environmental management control tools.It contributes to broadening the field’s vision and then offers recommendations for future studies.
文摘ⅡEnvironmental education is gaining increasing recognition in Morocco as a fundamental pillar for achieving the Sustainable Development Goals(SDGs).Within this context,school-based environmental clubs play a crucial role in promoting awareness and building climate resilience among students at various educational levels.These clubs serve not only as platforms for ecological engagement but also as practical tools for embedding sustainability into everyday learning.This study explores the main factors that influence the creation,activation,and effectiveness of environmental clubs in Moroccan schools.Relying on a quantitative survey conducted with 42 respondents,including both teachers and school administrators,the research highlights several key enablers.Among the most significant are access to adequate training in environmental education,the presence of strong institutional support,and the availability of sufficient resources.The analysis uses descriptive statistics,chi-square testing,and a Weighted Average Index to better understand the relationships between these variables.Findings reveal a strong correlation between environmental training and the initiation of clubs,although this does not always translate into high levels of student engagement.The main obstacles identified include insufficient time,lack of funding,and a shortage of appropriate educational materials.In conclusion,the study emphasizes the importance of expanding training initiatives,dedicating specific time within school schedules,and improving access to materials.These steps are essential to fully integrate environmental clubs into the Moroccan educational system and to enhance their overall impact.
文摘During times of war, it is rare to find a government willing and able to require the military to fund and support environmental impact studies. In the 1960s, many United States scientists expressed concerns about the use of herbicides during the Vietnam War. This protest was led by Dr. Arthur Galston and eventually included scientists with the National Academy of Science. By 1970, the Department of Defense (DoD) was ordered to permit the scientists to visit South Vietnam during the war to document these impacts. In all 1500 scientist days were spent in South Vietnam. In addition, the US government and military funded research studies on the impact of herbicides on animals. The goal of military use of herbicides, as chemical weapons, was to defoliate jungle forests and destroy food crops as a strategy to win battles and the war. The primary objective of this research study is to describe how it is possible for a country to fund and carry out scientific studies during the conduct of a war rather than decades later. The environmental impact study findings often lack boots on the ground validation and can be inaccurate or misleading in some situations. The United States (US) and other countries, including Russia and Ukraine, need to learn the historical lessons from the US use of herbicides, containing dioxin TCDD and/or arsenic (As), as chemical weapons during the Vietnam War.
文摘The purpose of this study lies in exploring the role of materiality in environmental information disclosures under the securities laws of the United States and China,discussing the differences in the regulatory mechanism,limits of enforcement,and challenges of seeking global harmonization.The paper does a comparative legal analysis of statutory provisions,judicial interpretations,and regulatory frameworks of the U.S.Securities and Exchange Commission(SEC)and the China Securities Regulatory Commission(CSRC).Furthermore,it provides frameworks of global sustainability reporting such as the Task Force on Climate-related Financial Disclosures(TCFD)and the Global Reporting Initiative(GRI).The findings show that U.S.securities law uses a financial materiality standard with respect to what companies must disclose to investors.On the other hand,China’s regulatory approach has a double materiality in considering not only financial impacts but also wider environmental and social factors.Although there are these distinctions,both of these jurisdictions face issues of common obstruction such as ambiguities in materiality determination,inconsistent enforcement,and fear of greenwashing.This paper asserts that the U.S.and China regulatory frameworks need to converge more to promote greater corporate transparency and ESG disclosures.Regulators can even align disclosure practices with internationally recognized standards of work to add confidence for investors,fight off misleading sustainability claims and ensure accountable reporting in pertinent environments.The study concludes that the green challenges of global markets can only be tackled by regulating cooperative actions and using standardized reporting guidelines.
基金supported by the National Natural Science Foundation of China(Nos.21906179 and 22074098)Sichuan Science and Technology Program(No.2021ZYD0047)the Fundamental Research Funds for the Central Universities.
文摘As emerging pollutants,microplastics have recently received considerable attention owing to detection in various organisms and environments.Mass production and widespread use of plastic products increase their potential risks to humans owing to their persistent,mobile,and toxic properties.Numerous methods have been used to identify and quantify the various forms of microplastics,however,unified standards do not exist.In this review,we systematically summarize the sources,migration,transformation,and analytical methods for microplastics in diverse ecosystems,particularly the most recent sampling and identification techniques.Additionally,the environmental effects and health hazards of microplastics on aquatic and terrestrial systems,as well as human beings are discussed.We also present management strategies for reducing microplastics in a broader social and policy context.This review aims to provide an overview of the migration,transformation,sampling,analysis,and environmental effects of microplastics,which addresses knowledge gaps in microplastic pollution and provides proposals for key research gaps.
基金supported by the National Key Research and Development Program of China under the theme“Research on urban sustainable development evaluation data fusion management technology”[Grant No.2022YFC3802903]Open Fund of Key Laboratory of Urban Land Resources Monitoring and Simulation,Ministry of Natural Resources[Grant No.KF-2022-07-013]。
文摘Urban eco-environmental management is a key focus in the modernization of national governance systems and governance capacity.Advanced information technology should be used to identify ecological problems in urban areas accurately while enhancing the environmental management capacity to promote the sustainable development of cities.This study centers on statistical data from PM_(2.5)air monitoring stations in Shenzhen,China,and supplemental data,such as population distribution data from China Unicom’s mobile phone signaling.Data cleaning and fusion are used to construct a spatial dataset of an eco-environmental problem:PM_(2.5)concentrations.The geostatistical analysis tool ArcGIS is used to identify the most suitable interpolation method for reflecting this eco-environmental problem based on multiple parameter adjustments and repeated testing.A hotspot distribution map of PM_(2.5)concentrations is generated,and correlation analysis is conducted on the population density and distribution patterns in these hotspot areas.This enables the quantitative analysis and exploration of the spatial characteristics and coupling relationships of PM_(2.5)concentrations.The results show a positive correlation between the PM_(2.5)concentration distribution and the points of interest,road network density,number of dead-end roads,and average building height in Shenzhen.No correlation is found between population and building densities and the PM_(2.5)concentration distribution,possibly due to the city’s effective environmental management and pollution control measures.These findings help advance the development of precise,scientific,legally compliant pollution control strategies and decision-making processes.Furthermore,they provide technical support for urban eco-environmental planning,management,and sustainable development.
基金funded by Key Project of Education and Teaching Reform and Research at Beijing Institute of Petrochemical Technology(ZD20200508).
文摘This study assesses the potential and benefits of reducing plastic consumption at the institutional level by taking the Beijing Institute of Petrochemical Technology(BIPT)in China as the case.By tracking the plastic material flow on the BIPT campus,we provide insights into the efforts required to achieve a plastic-free campus.A mixed-methods approach was employed,encompassing material flow analysis,quantitative analysis of influencing factors,examination of best practices in universities,and market price-based valuation of plastic reduction.The main conclusions are as follows:(1)Each student consumed an average of 9.2 kg of plastics for daily use on BIPT campus in the base year of 2020,with campus canteens,off-campus cafés,and shops(offline and online)contributing to 36%,31%and 30%respectively.(2)BIPT has a reduction potential of 45%,equivalent to 4.1 kg per student annually,yielding benefits of 45 RMB from savings in oil material and production energy,avoiding plastic waste,and reducing carbon emission.(3)If all global tertiary institutions set a target of reducing plastics by 4.1 kg per student,1.94 Mt of plastics could be avoided by 2035.(4)Greater reductions and benefits could be achieved if tertiary institutions extend their efforts across all campus activities,with substantial indirect and long-term contributions ranging from more sustainable campus management to fostering a transition towards a green economy.These findings highlight that plastic-free initiatives require contextual construction and environmental education both on and off campus.
文摘Six new lanthanide complexes:[Ln(3,4-DEOBA)3(4,4'-DM-2,2'-bipy)]2·2C_(2)H_(5)OH,[Ln=Dy(1),Eu(2),Tb(3),Sm(4),Ho(5),Gd(6);3,4-DEOBA-=3,4-diethoxybenzoate,4,4'-DM-2,2'-bipy=4,4'-dimethyl-2,2'-bipyridine]were successfully synthesized by the volatilization of the solution at room temperature.The crystal structures of six complexes were determined by single-crystal X-ray diffraction technology.The results showed that the complexes all have a binuclear structure,and the structures contain free ethanol molecules.Moreover,the coordination number of the central metal of each structural unit is eight.Adjacent structural units interact with each other through hydrogen bonds and further expand to form 1D chain-like and 2D planar structures.After conducting a systematic study on the luminescence properties of complexes 1-4,their emission and excitation spectra were obtained.Experimental results indicated that the fluorescence lifetimes of complexes 2 and 3 were 0.807 and 0.845 ms,respectively.The emission spectral data of complexes 1-4 were imported into the CIE chromaticity coordinate system,and their corre sponding luminescent regions cover the yellow light,red light,green light,and orange-red light bands,respectively.Within the temperature range of 299.15-1300 K,the thermal decomposition processes of the six complexes were comprehensively analyzed by using TG-DSC/FTIR/MS technology.The hypothesis of the gradual loss of ligand groups during the decomposition process was verified by detecting the escaped gas,3D infrared spectroscopy,and ion fragment information detected by mass spectrometry.The specific decomposition path is as follows:firstly,free ethanol molecules and neutral ligands are removed,and finally,acidic ligands are released;the final product is the corresponding metal oxide.CCDC:2430420,1;2430422,2;2430419,3;2430424,4;2430421,5;2430423,6.
基金supported by Qingdao Key Medical and Health Discipline ProjectThe Intramural Research Program of the Affiliated Hospital of Qingdao University,No. 4910Qingdao West Coast New Area Science and Technology Project,No. 2020-55 (all to SW)。
文摘Border-associated macrophages are located at the interface between the brain and the periphery, including the perivascular spaces, choroid plexus, and meninges. Until recently, the functions of border-associated macrophages have been poorly understood and largely overlooked. However, a recent study reported that border-associated macrophages participate in stroke-induced inflammation, although many details and the underlying mechanisms remain unclear. In this study, we performed a comprehensive single-cell analysis of mouse border-associated macrophages using sequencing data obtained from the Gene Expression Omnibus(GEO) database(GSE174574 and GSE225948). Differentially expressed genes were identified, and enrichment analysis was performed to identify the transcription profile of border-associated macrophages. CellChat analysis was conducted to determine the cell communication network of border-associated macrophages. Transcription factors were predicted using the ‘pySCENIC' tool. We found that, in response to hypoxia, borderassociated macrophages underwent dynamic transcriptional changes and participated in the regulation of inflammatory-related pathways. Notably, the tumor necrosis factor pathway was activated by border-associated macrophages following ischemic stroke. The pySCENIC analysis indicated that the activity of signal transducer and activator of transcription 3(Stat3) was obviously upregulated in stroke, suggesting that Stat3 inhibition may be a promising strategy for treating border-associated macrophages-induced neuroinflammation. Finally, we constructed an animal model to investigate the effects of border-associated macrophages depletion following a stroke. Treatment with liposomes containing clodronate significantly reduced infarct volume in the animals and improved neurological scores compared with untreated animals. Taken together, our results demonstrate comprehensive changes in border-associated macrophages following a stroke, providing a theoretical basis for targeting border-associated macrophages-induced neuroinflammation in stroke treatment.
基金supported by U01OH012263,and U01 OH012622 from the National Institute for Occupational Safety and HealthPCF 604934 from Prevent Cancer Foundation+1 种基金National Institutes of Health(NIH)/National Cancer Institute(NCI)1U01CA288425–0P30 ES023515 from the National Institute of Environmental Health Sciences.
文摘This study aimed to identify the worst“bad actors”in mixtures of pollutants contributing to liver damage and shorter telomeres in the U.S.population,using weighted quantile sum(WQS)modeling with stratification by race/ethnicity.We conducted a comprehensive cross-sectional analysis of mixtures of pollutants in National Health and Nutrition Examination Survey datasets:(1)33,979 adults with blood levels of cadmium(Cd),lead(Pb),and mercury,including subsets with measurements of per-/polyfluoroalkyl substances(PFAS),and polychlorinated biphenyls(PCBs)/polychlorinated dibenzo-p-dioxins and dibenzofurans(PCDD/Fs);and(2)7360 adults with measurements of telomeres,Cd,and Pb.Multivariable-adjusted WQS regression examined associations between WQS mixture indices and liver injury(alanine aminotransferase(ALT)-elevation),advanced liverfibrosis(LF),and telomere length.WQSmetal indices were associated with advanced-LF in all racial/ethnic groups.The top contributor was Cd in the total population and in non-Hispanic Whites(NHW),while Pb was the top contributor in non-Hispanic Blacks(NHB).The WQSmetal-PCB-PCDD/F index was associated with ALT-elevation,with PCB126,Cd and Pb as main contributors;the odds ratio(OR)per decile was 1.50(95%CI,1.26–1.78),while the OR per decile of the WQSmetal-PFAS index was 1.03(95%CI,0.98–1.05),not significant.WQS_(metal indices)were associated with shorter telomeres.Cd was main contributor associated with advanced-LF in NHW,while Pb was the major bad actor in NHB,suggesting that NHB may be especially susceptible to Pb toxicity.Metals were associated with shorter telomeres.Metal and PCB/PCDD/F mixtures were associated with ALT-elevation.Heavy metals and organic chemicals may contribute to liver-related morbidity and healthcare disparities.
基金supported by the Innovation Promotion Program of NHC and Shanghai Key Labs,SIBPT(grant number PT2025-01)。
文摘Human cardiac organoids have revolutionized the study of cardiac development,disease modeling,drug discovery,and regenerative therapies.This review systematically discusses strategies and progress in the construction of cardiac organoids,categorizing them into three main types:cardiac spheroids,self-organizing/assembloid organoids,and organoid-on-a-chip systems.This review uniquely integrates the advances in vascularization,organ-on-chip design,and environmental cardiotoxicity modeling within cardiac organoid platforms,offering a critical synthesis that is absent in the literature.In the context of escalating environmental threats to cardiovascular health,there is an urgent need for physiologically relevant models to accurately identify cardiac toxicants and elucidate their underlying mechanisms of action.This review highlights advances in cardiac organoid applications for disease modeling—including congenital heart defects and acquired cardiovascular diseases—drug development,toxicity screening,and the study of environmentally induced cardiovascular pathogenesis.In addition,it critically examines ongoing challenges and underscores opportunities brought by bioengineering approaches.Finally,we propose future directions for developing standardized cardiac organoid platforms with clinical predictability,aiming to expand the utility of this technology across broader research applications.
基金supported by the National Natural Science Foundation of China(Grant No.32160172)the Key Science-Technology Project of Inner Mongolia(2023KYPT0010)+1 种基金the Natural Science Foundation of Inner Mongolia Autonomous Region of China(Grant No.2025QN03006)the 2023 Inner Mongolia Public Institution High-Level Talent Introduction Scientific Research Support Project.
文摘Environmental DNA(eDNA)technology has revolutionized biodiversity monitoring with its non-invasive,sensitive,and cost-efficient approach.This paper systematically reviews eDNA advancements,examining its applications in aquatic and terrestrial ecosystems and assessing China’s standardization progress.It delineates four developmental phases from single-species detection to high-throughput sequencing,and highlights China’s contribution to the development of technical standards.While significant progress has been made,challenges persist in quantitative accuracy,methodological consistency,and large-scale implementation.Future efforts should prioritize enhanced standardization,improved quantification techniques,broader applications,and international collaboration to drive innovation in eDNA technology.
基金supported by grants from the Tianjin Health Technology Project(Grant no.2022QN106).
文摘Background:Receptor-interacting protein kinases(RIPKs)regulate cell death,inflammation,and immune responses,yet their roles in cancer are not fully understood.This study investigates the expression,genomic alterations,and functional implications of RIPK family members across various cancers.Methods:We collected multi-omics data from The Cancer Genome Atlas and other public databases,including gene expression,copy number variation(CNV),mutation,methylation,tumor mutation burden(TMB),and microsatellite instability(MSI).Differential expression and survival analyses were performed using DESeq2 and Cox proportional hazards models.CNV and mutation data were analyzed with GISTIC2 and Mutect2,and methylation data with the ChAMP package.Correlations with TMB and MSI were assessed using Pearson coefficients,and gene set enrichment analysis was conducted with the MSigDB Hallmark gene sets.Results:RIPK family members show significant differential expression in various cancers,with RIPK1 and RIPK4 frequently altered.Survival analysis reveals heterogeneous impacts on overall survival.CNV and mutation analyses identify high alteration frequencies for RIPK2 and RIPK7,affecting gene expression.RIPK1 and RIPK7 are hypermethylated in several cancers,inversely correlating with RIPK3 expression.RIPK1,RIPK2,RIPK5,RIPK6,and RIPK7 correlate positively with TMB,while RIPK3 shows negative correlations in some cancers.MSI analysis indicates associations with DNA mismatch repair.G ene set enrichment analysis highlights immune-related pathway enrichment for RIPK1,RIPK2,RIPK3,and RIPK6,and cell proliferation and DNA repair pathways for RIPK4 and RIPK5.RIPK family members showed heterogeneous alterations across cancers:for example,RIPK7 was mutated in up to~15%of u terine c orpus e ndometrial c arcinoma and l ung s quamous c ell c arcinoma cases,and RIPK1 and RIPK7 exhibited frequent promoter hypermethylation in multiple tumor types.Several genes displayed context-dependent associations with overall survival and with TMB/MSI.Conclusion:This pan-cancer analysis of the RIPK family reveals their diverse roles and potential as biomarkers and therapeutic targets.The findings emphasize the importance of RIPK genes in tumorigenesis and suggest context-dependent functions across cancer types.Further studies are needed to explore their mechanisms in cancer development and clinical applications.
基金funded by the National Natural Science Foundation of China(42361017)the Gansu Provincial Science and Technology Program-Special Program for Key Research and Development(R&D)on Ecological Civilization Construction in Gansu Province(24YFFA050)the Gansu Agricultural University-Gansu Provincial Academy of Natural Resources Planning Joint Graduate Training Base Project(GAU2024-003)。
文摘The Loess Plateau(LP),one of the most ecologically fragile regions in China,is affected by severe soil erosion and environmental degradation.Despite large-scale ecological restoration efforts made by Chinese government in recent years,the region continues to face significant ecological challenges due to the combined impact of climate change and human activities.In this context,we developed a kernal Remote Sensing Ecological Index(kRSEI)using Moderate Resolution Imaging Spectroradiometer(MODIS)products on the Google Earth Engine(GEE)platform to analyze the spatiotemporal patterns and trends in ecological environmental quality(EEQ)across the LP from 2000 to 2022 and project future trajectories.Then,we applied partial correlation analysis and multivariate regression residual analysis to further quantify the relative contributions of climate change and human activities to EEQ.During the study period,the kRSEI values exhibited significant spatial heterogeneity,with a stepwise degradation pattern in the southeast to northwest across the LP.The maximum(0.51)and minimum(0.46)values of the kRSEI were observed in 2007 and 2021,respectively.Trend analyses revealed a decline in EEQ across the LP.Hurst exponent analysis predicted a trend of weak anti-persistent development in most of the plateau areas in the future.A positive correlation was identified between kRSEI and precipitation,particularly in the central and western regions;although,improvements were limited by a precipitation threshold of 837.66 mm/a.A moderate increase in temperature was shown to potentially benefit the ecological environment within a certain range;however,temperature of-1.00°C-7.95°C often had a negative impact on the ecosystem.Climate change and human activities jointly influenced 65.78%of LP area on EEQ,primarily having a negative impact.In terms of contribution,human activities played a dominant role in driving changes in EEQ across the plateau.These findings provide crucial insights for accurately assessing the ecological state of the LP and suggest the design of future restoration strategies.
基金the Natural Science Basic Research Program of Shaanxi Province,China[2023-JC-QN-0858]the Free Exploration Program of the Second Affiliated Hospital,School of Medicine,Xi’an Jiaotong University[2020YJ(ZYTS)605]the National Natural Science Foundation of China[81900620].
文摘Global environmental changes including climate warming,extreme weather events,ambient air pollution,freshwater contamination,and landscape transformation are reshaping the epidemiology of infectious diseases with unprecedented complexity,particularly in the post-COVID-19 era.This review synthesizes evidence from the past decade(2015-2024)to systematically elucidate how key environmental drivers modulate pathogen emergence,transmission dynamics,and clinical outcomes,with a focus on underlying mechanistic pathways.Specifically,we highlight:(1)the temperature-and precipitation-dependent transmission of vector-borne diseases(e.g.,malaria,dengue)via expanded vector habitats and accelerated pathogen incubation;(2)the exacerbation of respiratory infections(including COVID-19)by particulate matter(PM2.5)and nitrogen dioxide(NO2)through impaired mucosal immunity and enhanced inflammatory responses;(3)the persistence of diarrheal diseases in low-and middle-income countries(LMICs)linked to water insecurity and climate-induced infrastructure failure;and(4)zoonotic spillover risks amplified by urbanization and deforestation-driven human-wildlife interface disruption.Integrating the One Health socioecological framework,we further summarize methodological advances from high-resolution genomic surveillance to climate-informed machine learning models that have improved causal inference and predictive accuracy.Our synthesis confirms that environmental factors are not merely contextual but central,modifiable determinants of infectious disease risk,with disproportionate impacts on vulnerable populations.To mitigate future threats,we emphasize the urgency of interdisciplinary collaboration,integrated environmental-health monitoring platforms,and climate-resilient public health policies tailored to post-pandemic challenges.This review provides a timely roadmap for translating environmental epidemiology insights into actionable strategies to strengthen global health resilience.
基金financially supported by the National Natural Science Foundation of China(Nos.52034002 and U2202254)the Fundamental Research Funds for the Central Universities,China(No.FRF-TT-19-001)。
文摘The sulfation and decomposition process has proven effective in selectively extracting lithium from lepidolite.It is essential to clarify the thermochemical behavior and kinetic parameters of decomposition reactions.Accordingly,comprehensive kinetic study by employing thermalgravimetric analysis at various heating rates was presented in this paper.Two main weight loss regions were observed during heating.The initial region corresponded to the dehydration of crystal water,whereas the subsequent region with overlapping peaks involved complex decomposition reactions.The overlapping peaks were separated into two individual reaction peaks and the activation energy of each peak was calculated using isoconversional kinetics methods.The activation energy of peak 1 exhibited a continual increase as the reaction conversion progressed,while that of peak 2 steadily decreased.The optimal kinetic models,identified as belonging to the random nucleation and subsequent growth category,provided valuable insights into the mechanism of the decomposition reactions.Furthermore,the adjustment factor was introduced to reconstruct the kinetic mechanism models,and the reconstructed models described the kinetic mechanism model more accurately for the decomposition reactions.This study enhanced the understanding of the thermochemical behavior and kinetic parameters of the lepidolite sulfation product decomposition reactions,further providing theoretical basis for promoting the selective extraction of lithium.
基金supported by Natural Science Foundation of Xiamen,China(No.3502Z20227232)the STS Project of Fujian-CAS(No.2023T3018)Bureau of International Cooperation,Chinese Academy of Sciences(No.322GJHZ2022035MI).
文摘Anammox bacteria in constructed wetlands(CWs)play pivotal role in sustainable nitrogen transformation,yet existing studies lack comprehensive analysis of environmental gradients and microbial interactions,both key factors in anammox bacteria enrichment.This study investigated the mechanisms driving anammox bacteria enrichment in lab-scale simulated CWs treating high-nitrogen wastewater,focusing on bacterial community re-sponses across wetland layers with various strategies,including continuous up-flow influent,nitrogen loading increase,effluent recirculation,intermittent influent,and anammox bacteria inoculation.Results showed that total relative and absolute abundances of anammox bacteria ranged from 0.77%to 12.50%and from 0.13 to 6.46×10^(7) copies/g,respectively.Dissolved oxygen and pH had significant positive correlations with the absolute abundance of anammox bacteria,while organic matter and nitrate negatively impacted their relative abundance.Permutational multivariate analysis of variance indicated that spatial heterogeneity explained more variation in anammox bacteria abundance(43.44%)compared to operational strategies(8.58%).In terms of microbial interactions,60 dominant species exhibited potential correlations with anammox bacteria,comprising 170 interactions(105 positive and 65 negative),which suggested that anammox bacteria generally foster cooperative relationships with dominant bacteria.Notably,significant interspecies interactions were observed between Candidatus Kuenenia(dominant anammox bacteria in CWs)and species within the genera Chitinivibrio-nia and Anaerolineaceae,suggesting that microbial interactions primarily manifest as indirect facilitative effects rather than direct mutualistic relationships.Given that the Normalized Stochasticity Ratio in CWs were<50%,this study inferred that environmental gradients have greater influence on anammox bacteria than microbial interactions.
基金supported by the National Key R&D Program of China(Nos.2018YFC1004300 and 2018YFC1004302)the Science&Technology Program of Guizhou Province(Nos.QKHHBZ[2020]3002,QKHPTRC-GCC[2022]039-1 and QKHPTRCCXTD[2022]014)the Scientific Research Program of Guizhou Provincial Department of Education(No.QJJ[2023]019).
文摘Despite the widespread presence and frequent detection of polycyclic aromatic hydrocarbons(PAHs)in various aspects of life,there is limited research on their exposure levels in pregnant women and cumulative exposure from the living environment.This study included 1311 women in late pregnancy from the Zunyi birth cohort and measured the urinary concentrations of 10 hydroxylated PAH metabolites(OH-PAHs).Risk assessment was conducted based on the estimated daily intake to calculate the hazard quotient and hazard index(HI).A linear regression model was used to analyze the relationship between creatinine-adjusted OH-PAHs concentrations and living environment and lifestyle factors,while principal component analysis was applied to trace the sources of PAHs exposure.1-OHPYR was detected in all participants’urine,with naphthalene metabolites having the highest concentrations among creatinine-adjusted PAHs.OH-PAHs concentrations were associated with housing type,room number,cooking frequency,household size,exercise frequency,fuel type,distance from main road,and drinking water source.Pregnant women using traditional fuels and living in bungalows had higher health risks than those using clean energy and living in buildings.Those living within 100 m of a main road had higher HI than those farther away.Coal combustion was identified as the primary source of PAHs exposure.The study emphasizes the importance of reducing PAHs exposure,especially for pregnant women living in polluted environments.It recommends public health interventions such as improving indoor ventilation and providing clean energy to reduce related health risks.
基金National Natural Science Foundation of china(No.U2241205)the Natural Science Basic Research Program of Shaanxi(Nos.2022JC-33,2023-GHZD-35,and 2024JC-ZDXM-25)+1 种基金the Fundamental Research Funds for the Central Universitiesthe National 111 Project to provide fund for conducting experiments。
文摘In this study,the design,analysis,manufacturing,and testing of a 3D-printed conformal microstrip array antenna for high-temperature environments is presented.3D printing technology is used to fabricate a curved ceramic substrate,and laser sintering and microdroplet spraying processes are used to add the conductive metal on the curved substrate.The problems of gain loss,bandwidth reduction,and frequency shift caused by high temperatures are addressed by using a proper antenna design,with parasitic patches,slots,and metal resonant cavities.The antenna prototype is characterized by the curved substrates and the conductive metals for the power dividers,the patch,and the ground plane;its performance is examined up to a temperature of 600℃in a muffle furnace and compared with the results from the numerical analysis.The results show that the antenna can effectively function at 600℃and even higher temperatures.
基金Suppotred by Tianjin Key Medical Discipline Construction Project(No.TJYXZDXK-3-004A-2).
文摘AIM:To present an overview of the research on global glaucoma treatment in the last decade in terms of publication year,journals,countries/regions,organizations,references,and keywords,to investigate the current research international trends and hot topics in this area.METHODS:Bibliometric analysis was conducted on 9128 articles in the Web of Science Core Collection(WoSCC;Clarivate)database.Quantitative and qualitative analysis was employed using VOSviewer(v1.6.18),Pajek(v1.0.0.0),and CiteSpace(v6.1.R2)software.RESULTS:The 9128 papers relating to glaucoma treatment were published from April 2013 to April 2023,of which 7482 articles(82%)were original research articles and 1464(18%)were review articles.The United States(2867)and Johns Hopkins University(166)were the most productive country and institution,respectively,but the University College London had the highest h-index(54).The Journal of Glaucoma was the most productive and Ophthalmology had the highest h-index compared with other journals.The Keywords of interest included treatment surgery,cyclophotocoagulation,minimally invasive glaucoma surgery(MIGS),trabeculectomy,baerveldt,epidemiology,medication adherence,nanoparticle,optical coherence tomography(OCT),gene therapy,and artificial intelligence(AI).Glaucoma surgery appeared as a current research hotspot through the analysis of keywords.CONCLUSION:This study provides insights into the research trends and potential research hotspots in the treatment of glaucoma.This will help researchers to evaluate research policies and to promote international cooperation.
