In order to resolve the increasing resistance phenomena of the Gram-negative bacteria against single chain quaternary ammonium salts （QAS）, lysine with a pedant fluorinated bis-ammonium salts was synthesized and its...In order to resolve the increasing resistance phenomena of the Gram-negative bacteria against single chain quaternary ammonium salts （QAS）, lysine with a pedant fluorinated bis-ammonium salts was synthesized and its antimicrobial properties were evaluated in this work. The novel fluorinated bis-ammonium salts shows similar activity with conventional single chain quaternary ammonium salts against Gram-positive bacteria but stronger activity against Gram-negative bacteria and yeast compared with the single chained counterpart.展开更多
Over the past decade, biopolymers have gained great interests especially in biomedicine due to their physical properties and/or chemical structures changes in response to external stimuli in a certain time fiarne or a...Over the past decade, biopolymers have gained great interests especially in biomedicine due to their physical properties and/or chemical structures changes in response to external stimuli in a certain time fiarne or at a specific location. Among them, poly（β-amino ester）s, methacrylate-based block copolymers and polypeptide with tertiary amine groups have been extensively studied and exhibit pH sensitive properties due to the protonation of tertiary amine groups. The pH values in normal organs, tissues, and subcellular compartments are always different from those in pathological tissues. These interesting properties allow their applications in a variety of fields ranging from diagnosis and therapeutics of diseases. Here, we review the recent progress of poly（β-amino ester）s, methacrylate-based block copolymers and polypeptide with tertiary amine groups and their applications in drug delivery and bioimaging.展开更多
A mesoporous UiO-66-NH_(2) aerogel is prepared via a straightforward sol-gel method without using any binders or mechanical pressures, in which the amine groups are directly introduced into the matrix by using 2-amino...A mesoporous UiO-66-NH_(2) aerogel is prepared via a straightforward sol-gel method without using any binders or mechanical pressures, in which the amine groups are directly introduced into the matrix by using 2-aminoterephthalic acid. The novel UiO-66-NH_(2) aerogel also exhibits high specific surface area and mesopore-dominated structure, implying its highly potential use in CO_(2) adsorption. For ulteriorly investigating the effect of amine loading on the CO_(2) adsorption ability, a series of UiO-66-NH_(2) aerogel with different amino content is fabricated by changing the ligand/metal molar ratio. When the molar ratio is 1.45, the CO_(2) adsorption capacity reaches the optimum value of 2.13 mmol·g^(-1) at 25 ℃ and 0.1 MPa, which is 12.2% higher than that of pure UiO-66 aerogel. Additionally, UiO-66-NH_(2)-1.45 aerogel also has noticeable CO_(2) selectivity against N_(2) and CH_(4) as well as good regeneration stability. Such results imply that it has good application prospect in the field of CO_(2) adsorption, and also contains the potential to be applied in catalysis, separation and other fields.展开更多
Seeking effective solutions to control and mitigate the interaction between drilling fluids and clay formations has been a challenge for many years, and various shale inhibitors have shown excellent results in problem...Seeking effective solutions to control and mitigate the interaction between drilling fluids and clay formations has been a challenge for many years, and various shale inhibitors have shown excellent results in problematic shale formations around the world. Herein, the hyperbranched polyamine (HBPA) inhibitor with a higher ratio of amine groups and obvious tendentiousness in protonation was successfully synthesized from ethylenediamine, acryloyl chloride and aziridine by five steps, in which the metal-organic framework (MOF) was employed as a catalyst for ring-open polycondensation (ROP). The structure and purity were confirmed by nuclear magnetic resonance hydrogen spectroscopy and high-performance liquid chromatography (HPLC) respectively. The HBPA displays more excellent performance than EDA and KCl widely applied in the oil field. After aging at 80°C and 180°C, the YP of a slurry system containing 25 wt.% bentonite and 2 wt.% HBPA are just 8.5 Pa and 5.5 Pa (wt.%: percentage of mass), respectively. The swelling lengths of 2 wt.% HBPA are estimated to be 1.78 mm, which falls by 70% compared with that of freshwater. Under a hot rolling aging temperature of 180°C, the HBPA system demonstrates a significant inhibition with more than 85% shale cuttings recovery rate and is superior to conventional EDA and KCl. Mechanism analysis further validates that the HBPA can help to increase the zeta potential.展开更多
Copolyesters having secondary and tertiary amine salt groups in the main and side chains are prepared by chemoselective polymerization. These copolyesters are soluble in a 10% aqueous solution of poly(vinyl alcohol) ...Copolyesters having secondary and tertiary amine salt groups in the main and side chains are prepared by chemoselective polymerization. These copolyesters are soluble in a 10% aqueous solution of poly(vinyl alcohol) (PVA) at 90 degree C and act as plasticizer in the blend films cast from the solution. Only a glass transition temperature is observed for all these blends indicating the formation of compatible blends from these polyesters with PVA. These blends exhibit manifold characteristics such as ionic conductivity, complex formation with metal ions, absorption of moisture and color changes. The electric conductivity of the copolyesters and blends is in the range of 10** minus **6 Scm** minus **1. The blends with PVA forms complexes with Cu**2** plus and Co**2** plus . The coordination structure with two chelate rings is suggested for these polymer blend/metal complexes. (Author abstract) 10 Refs.展开更多
Ionized amine group(R-NH_(2))and carboxyl group(R-COOH)within the active layer of polyamide(PA)nanofiltration membranes result in the formation of positive(R-NH_(3)^(+))and negative(R-COO^(-))functional groups,respect...Ionized amine group(R-NH_(2))and carboxyl group(R-COOH)within the active layer of polyamide(PA)nanofiltration membranes result in the formation of positive(R-NH_(3)^(+))and negative(R-COO^(-))functional groups,respectively,which determines membrane performance and is essential for membrane fabrication and modification.Herein,a facile dye adsorption/desorption method using Orange II and Toluidine Blue O dyes was developed to measure the densities of R-NH2,R-,R-COOH,or R-COO^(-)on surfaces of six PA membranes,and the correlation between the density of such groups and the zeta potential was established.The dye adsorption method was proven reliable due to its lower standard deviation,detection limit,and quantification limit values.Furthermore,the densities of R-or R-COO^(-)under different pH values were measured,fitting well with results calculated from the acid-base equilibrium theory.Additionally,a correlation was established between the net surface density([R-NH_(3)^(+)]-[R-COO^(-)])and the surface charge density(σ)calculated via the Gouy-Chapman model based on zeta potential results.The resulted correlation(σ/(mC·m^(-2))=(3.67±0.08)×([R-NH_(3)^(+)]−[R-COO^(-)])/(nmol·cm^(-2))+(0.295±0.08))effectively predicts theσvalue of the membrane.This study provides a facile and reliable dye adsorption method for measuring the density of R-NH2,R-NH_(3)^(+),R-COOH,or R-COO^(-),enabling an in-depth understanding of membrane charge properties.展开更多
文摘In order to resolve the increasing resistance phenomena of the Gram-negative bacteria against single chain quaternary ammonium salts （QAS）, lysine with a pedant fluorinated bis-ammonium salts was synthesized and its antimicrobial properties were evaluated in this work. The novel fluorinated bis-ammonium salts shows similar activity with conventional single chain quaternary ammonium salts against Gram-positive bacteria but stronger activity against Gram-negative bacteria and yeast compared with the single chained counterpart.
文摘Over the past decade, biopolymers have gained great interests especially in biomedicine due to their physical properties and/or chemical structures changes in response to external stimuli in a certain time fiarne or at a specific location. Among them, poly（β-amino ester）s, methacrylate-based block copolymers and polypeptide with tertiary amine groups have been extensively studied and exhibit pH sensitive properties due to the protonation of tertiary amine groups. The pH values in normal organs, tissues, and subcellular compartments are always different from those in pathological tissues. These interesting properties allow their applications in a variety of fields ranging from diagnosis and therapeutics of diseases. Here, we review the recent progress of poly（β-amino ester）s, methacrylate-based block copolymers and polypeptide with tertiary amine groups and their applications in drug delivery and bioimaging.
基金supported by the National Natural Science Foundation of China (21603125)Science-Education-Industry Integration Innovation Pilot Project of Qilu University of Technology (2020KJC-GH13)+2 种基金International Cooperation Project of Shandong Academy of Sciences (2019GHPY09)Natural Science Foundation of Shandong Province (ZR2019BEM025)Young doctor Cooperation Foundation of Qilu University of Technology (Shandong Academy of Sciences) (2019BSHZ0016)。
文摘A mesoporous UiO-66-NH_(2) aerogel is prepared via a straightforward sol-gel method without using any binders or mechanical pressures, in which the amine groups are directly introduced into the matrix by using 2-aminoterephthalic acid. The novel UiO-66-NH_(2) aerogel also exhibits high specific surface area and mesopore-dominated structure, implying its highly potential use in CO_(2) adsorption. For ulteriorly investigating the effect of amine loading on the CO_(2) adsorption ability, a series of UiO-66-NH_(2) aerogel with different amino content is fabricated by changing the ligand/metal molar ratio. When the molar ratio is 1.45, the CO_(2) adsorption capacity reaches the optimum value of 2.13 mmol·g^(-1) at 25 ℃ and 0.1 MPa, which is 12.2% higher than that of pure UiO-66 aerogel. Additionally, UiO-66-NH_(2)-1.45 aerogel also has noticeable CO_(2) selectivity against N_(2) and CH_(4) as well as good regeneration stability. Such results imply that it has good application prospect in the field of CO_(2) adsorption, and also contains the potential to be applied in catalysis, separation and other fields.
文摘Seeking effective solutions to control and mitigate the interaction between drilling fluids and clay formations has been a challenge for many years, and various shale inhibitors have shown excellent results in problematic shale formations around the world. Herein, the hyperbranched polyamine (HBPA) inhibitor with a higher ratio of amine groups and obvious tendentiousness in protonation was successfully synthesized from ethylenediamine, acryloyl chloride and aziridine by five steps, in which the metal-organic framework (MOF) was employed as a catalyst for ring-open polycondensation (ROP). The structure and purity were confirmed by nuclear magnetic resonance hydrogen spectroscopy and high-performance liquid chromatography (HPLC) respectively. The HBPA displays more excellent performance than EDA and KCl widely applied in the oil field. After aging at 80°C and 180°C, the YP of a slurry system containing 25 wt.% bentonite and 2 wt.% HBPA are just 8.5 Pa and 5.5 Pa (wt.%: percentage of mass), respectively. The swelling lengths of 2 wt.% HBPA are estimated to be 1.78 mm, which falls by 70% compared with that of freshwater. Under a hot rolling aging temperature of 180°C, the HBPA system demonstrates a significant inhibition with more than 85% shale cuttings recovery rate and is superior to conventional EDA and KCl. Mechanism analysis further validates that the HBPA can help to increase the zeta potential.
文摘Copolyesters having secondary and tertiary amine salt groups in the main and side chains are prepared by chemoselective polymerization. These copolyesters are soluble in a 10% aqueous solution of poly(vinyl alcohol) (PVA) at 90 degree C and act as plasticizer in the blend films cast from the solution. Only a glass transition temperature is observed for all these blends indicating the formation of compatible blends from these polyesters with PVA. These blends exhibit manifold characteristics such as ionic conductivity, complex formation with metal ions, absorption of moisture and color changes. The electric conductivity of the copolyesters and blends is in the range of 10** minus **6 Scm** minus **1. The blends with PVA forms complexes with Cu**2** plus and Co**2** plus . The coordination structure with two chelate rings is suggested for these polymer blend/metal complexes. (Author abstract) 10 Refs.
基金support provided by the National Natural Science Foundation of China (Grant Nos. 52270014 and 51708556).
文摘Ionized amine group(R-NH_(2))and carboxyl group(R-COOH)within the active layer of polyamide(PA)nanofiltration membranes result in the formation of positive(R-NH_(3)^(+))and negative(R-COO^(-))functional groups,respectively,which determines membrane performance and is essential for membrane fabrication and modification.Herein,a facile dye adsorption/desorption method using Orange II and Toluidine Blue O dyes was developed to measure the densities of R-NH2,R-,R-COOH,or R-COO^(-)on surfaces of six PA membranes,and the correlation between the density of such groups and the zeta potential was established.The dye adsorption method was proven reliable due to its lower standard deviation,detection limit,and quantification limit values.Furthermore,the densities of R-or R-COO^(-)under different pH values were measured,fitting well with results calculated from the acid-base equilibrium theory.Additionally,a correlation was established between the net surface density([R-NH_(3)^(+)]-[R-COO^(-)])and the surface charge density(σ)calculated via the Gouy-Chapman model based on zeta potential results.The resulted correlation(σ/(mC·m^(-2))=(3.67±0.08)×([R-NH_(3)^(+)]−[R-COO^(-)])/(nmol·cm^(-2))+(0.295±0.08))effectively predicts theσvalue of the membrane.This study provides a facile and reliable dye adsorption method for measuring the density of R-NH2,R-NH_(3)^(+),R-COOH,or R-COO^(-),enabling an in-depth understanding of membrane charge properties.
