Polymer fibers are among the most promising adsorbents in wastewater treatment,while limited by poor adsorption capacity and irreversible pollution.Herein,amine-modified C_(3)N_(4)/TiO_(2)-polyacrylonitrile(PAN)compos...Polymer fibers are among the most promising adsorbents in wastewater treatment,while limited by poor adsorption capacity and irreversible pollution.Herein,amine-modified C_(3)N_(4)/TiO_(2)-polyacrylonitrile(PAN)composite fibers with high absorption ability and photocatalytic self-cleaning properties were fabricated via wet spinning.The introduction of diethylenetriamine(DETA)onto the PAN resulted in the presence of positively charged amino groups,which not only increased the number of adsorption sites for anionic dyes but also facilitated the formation of a sponge-like pore structure.Optimally,the adsorption capacity of the aminated PAN fibers(PD7h)for methyl orange(MO)reached 164.79 mg·g^(-1),which is 39.2 times greater than that of unmodified PAN fibers.Furthermore,the introduction of the C_(3)N_(4)/TiO_(2) heterojunction photocatalyst endowed the fibers with photocatalytic self-cleaning capability by generating active free radicals(hydroxyl radicals(·OH)and superoxide radicals(·O_(2)^(-))that efficiently degraded dye pollutants in situ on the fiber surface.Under irradiation using a 300 W xenon lamp,the aminated C_(3)N_(4)/TiO_(2)^(-)PAN fibers(PDCT-1)removed more than 90%of MO(30 mg·L^(-1))within 120 min.After eight cycles,the pollutant removal rate decreased by only 22.41%,indicating excellent stability.Overall,this work presents an effective,simple and feasible method for preparing polymer fibers with high adsorption and photocatalytic self-cleaning properties via wet spinning for dye wastewater treatment.展开更多
Konjac glucomannan （KGM） was aminated by 2-chloroethyl-amine （CEA） as reagent so as to study the influence of concentration of CEA （based on the amount of KGM）, concentration of NaOH, reaction time and temperatu...Konjac glucomannan （KGM） was aminated by 2-chloroethyl-amine （CEA） as reagent so as to study the influence of concentration of CEA （based on the amount of KGM）, concentration of NaOH, reaction time and temperature on the extent of amination. And the molecular simulation technology was adopted to analyze the conformation stability of aminate （AKGM）. The results indicate that when the amount of CEA is higher, the extent of amination is higher. The optimum concentration of NaOH, reaction time and temperature are 10% NaOH, 70 ℃ and 45 rain, respectively. IR shows KGM is successfully aminated. The conformation of AKGM is in a random clew-like shape.展开更多
Aminated tannins were prepared by reacting mimosa condensed tannin extract with ammonia yielding the substitution of many,if not all of the tannin hydroxyl groups with–NH_(2)groups.A tannin-aminated tannin(ATT)partic...Aminated tannins were prepared by reacting mimosa condensed tannin extract with ammonia yielding the substitution of many,if not all of the tannin hydroxyl groups with–NH_(2)groups.A tannin-aminated tannin(ATT)particleboard coating was then prepared by reacting raw tannin extract with aminated tannin extract and thus cross-linking the two by substituting tannin’s hydroxyl groups with the–NH_(2)groups on the aminated tannin to form–NH-bridges between the two.The resulting particleboard coating gave encouraging results when pressed at 180℃for 3 min.Conversely,the system in which tannin was reacted/cross-liked with urea(ATU)by a similar amination reaction did not perform as well as the ATT system,and this even when a higher curing temperature and longer hot press time were used.In particular its water repellence was worse probably due to the presence of urea and such a system with lower reactivity.Nonetheless,substituting the tannin–OHs with the urea–NH_(2)groups appeared to also take place.ATT gave better results than ATU as regards water repellence and mechanical resistance as shown by the cross cut test.The ATT system was shown to be between 95%and 98%biosourced.The difference appeared to be due,by TMA analysis,to the much faster formation of the ATT hardened network leading to a better cross-linked polymer coating.The chemical species formed for both the ATT and ATU system were studied by MALDI ToF and CP MAS^(13)C NMR.展开更多
An aminated hypercrosslinked macroporous polymeric adsorbent was synthesized and characterized. Adsorption isotherms for 1 amino 2 naphthol 4 sulfonic acid(1, 2, 4 acid) and 2 naphthol obtained from various bin...An aminated hypercrosslinked macroporous polymeric adsorbent was synthesized and characterized. Adsorption isotherms for 1 amino 2 naphthol 4 sulfonic acid(1, 2, 4 acid) and 2 naphthol obtained from various binary adsorption environments can be well fitted by Freundlich equation, which indicated a favorable adsorption process in the studied range. Adsorption for 1, 2, 4 acid was an endothermic process in comparison with that for 2 naphthol of an exothermic process. 2 naphthol molecules put a little influence on the adsorption capacity for 1, 2, 4 acid. However, the adsorption to 1, 2, 4 acid depressed that to 2 naphthol in a large extent for the stronger electrostatic interaction between 1, 2, 4 acid and adsorbent. The predominant mechanism can be contributed to the competition for adsorption sites. And the simultaneous environment was confirmed to be helpful to the selective adsorption towards 1,2,4 acid based on the larger selectivity index.展开更多
The new flow improvers for super-viscous crude oils were developed via esterification of polybasic high carbon alcohol with methacrylate and copolymerizafion of monomers followed by amination of copolymers. The struct...The new flow improvers for super-viscous crude oils were developed via esterification of polybasic high carbon alcohol with methacrylate and copolymerizafion of monomers followed by amination of copolymers. The structure of the synthesized polymer flow improver additive was confirmed by IR spectroscopy and the crystal structure of the flow improver additives were determined by X-ray diffrac- tion analysis. The structure of wax crystals was also studied at the same time. The results showed that the wax crystal structure was closely related with the crystal structure of the flow improver, which could change the pour point depression and viscosity reduction behavior of the crude oil. When the wax crystal structure matched well with that of the additive, the wax crystals were dispersed satisfactorily, resulting in favorable effects in terms of pour point depression and viscosity reduction. The new synthe- sized aminated polymer flow improver additive was most efficient for treating super-viscous crude oils. The super-viscous crude oil had a high content of resins and asphaltenes, which might aggregate onto the surface of wax crystals to form blocks to limit the crude oil fluidity. However, amination of copolymers having similar structure with the resins and asphaltenes contained in crude oil could dissolve the huge polar groups to make the deposit formation difficult.展开更多
In the present study we prepared macroporous polyvinyl alcohol beads. A series of bilirubin adsorbents were generated by immobilization of eight amine agents to the beads as ligands. The adsorption of bilirubin was ev...In the present study we prepared macroporous polyvinyl alcohol beads. A series of bilirubin adsorbents were generated by immobilization of eight amine agents to the beads as ligands. The adsorption of bilirubin was evaluated by in vitro static and dynamic adsorption tests. The results show that these adsorbents have excellent adsorption efficiency and capacity. Among the eight ligands, trimethylamine （TMA）, triethylamine （TEA） and 1,6- hexanediamine （HDA） showed the highest adsorption capacity. The adsorption equilibrium can be achieved in half an hour, and the adsorption percentage of bilirubin was up to 80%. Static electricity and hydrophobie interaction played the main role in bilirubin adsorption, and the adsorption was found to match the monolayer model. The excellent adsorption of these adsorbents indicates their potential in clinical treatment.展开更多
Recently biospecific affinity chromatography has been widely used for the separation and purification of various enzymes and nucleic acids. In this paper, a series of synthetic reactions of solid-liquid phase were car...Recently biospecific affinity chromatography has been widely used for the separation and purification of various enzymes and nucleic acids. In this paper, a series of synthetic reactions of solid-liquid phase were carried out on silica surface, using a macroporous(30 mu m), microspherical silica (8 mu m) as the matrix and gamma-aminopropyltriethoxysilane as the activating agent, the nicotinamide adenine dinucleotide(NAD) was bonded through its amino groups to the carboxylic groups of linked phospholipid which was bonded covalently on aminated support. The bonded stationary phase has high thermal stability, and could be used to separate of nucleotides with good resolution.展开更多
H-terminated DLC layers were synthesized on SiO 2 substrate by radio frequency (RF) magnetron plasma-enhanced chemical vapor deposition (PECVD) in a conventional reactor using C 4 H 10 as carbon source. As-deposited D...H-terminated DLC layers were synthesized on SiO 2 substrate by radio frequency (RF) magnetron plasma-enhanced chemical vapor deposition (PECVD) in a conventional reactor using C 4 H 10 as carbon source. As-deposited DLC films were characterized by Raman spectroscopy, scanning electron microscopy (SEM) as well as atomic force microscopy (AFM). The chemical reactivity of the obtained DLC surface was further investigated by exposing the photochemically oxidized DLC surface to a silane reagent. The course of the reaction was followed using water contact angle and X-ray photoelectron spectroscopy.展开更多
Peroxidase plays an important role in living systems;however,its storage difficulty and easy inactivation have limited its applications in complex environments.To address these problems,herein,we proposed a method to ...Peroxidase plays an important role in living systems;however,its storage difficulty and easy inactivation have limited its applications in complex environments.To address these problems,herein,we proposed a method to synthesize peroxidase mimics by amination,carbonization,and Fe^(3+)-doping of industrial alkali lignin.The Fe^(3+)-doped lignin-based peroxidase mimic(Fe-LPM),with active centers of coordination between Fe^(3+)and N atoms,showed higher tolerance to pH value and temperature than natural peroxidase.Using Fe-LPM,10-100 mmol/L of H_(2)O_(2) and glucose could be colorimetrically detected with the lowest detection limits of 80μmol/L and 1.5 mmol/L and visual detection limits of 1.0 mmol/L and 10 mmol/L,respectively.The Fe-LPM maintained peroxidase-like activity after 10 cycles and could even be used for H_(2)O_(2) detection in practical samples.This work not only provides a new approach to synthesize peroxidase mimics using biomass materials but also promotes the high-value utilization of lignin.展开更多
A new method for the preparation of aminated lignin （AEL） through etherification and amination reaction was presented. Chlorine atoms were ？rstly introduced into lignin through its etheri？cation with epichlo...A new method for the preparation of aminated lignin （AEL） through etherification and amination reaction was presented. Chlorine atoms were ？rstly introduced into lignin through its etheri？cation with epichlorohydrin. Then, hydrophilic amine groups were grafted to the modi？ed lignin structure through amination with ethylenediamine to obtain AEL. Subsequent acidi？cation of AEL led to the ionized aminated lignin （IAEL）. The results of our analyses showed that the nitrogen content of AEL was 6.9%. Foaming and emulsifying experiments indicated that AEL had better foamability and emulsifying properties than IAEL. Surface tension tests showed that AEL and IAEL had similar critical micelle concentration （CMC）. However, IAEL had lower surface tension （36.33 mN/m） than AEL （42.89 mN/m） at CMC. These results demonstrate the promising applicability of AEL as an emulsi？er and that of IAEL as feedstock in the production of detergent and dispersant.展开更多
A new aminated-perylenequinone derivative 2 was synthesized by the reaction of 1 (hypocrellin B) with 6-aminohexanoic-acid. The structure of 2 was identified by UV-Vis, MS, IR and H-1-NMR. Thc amphiphility spectrum an...A new aminated-perylenequinone derivative 2 was synthesized by the reaction of 1 (hypocrellin B) with 6-aminohexanoic-acid. The structure of 2 was identified by UV-Vis, MS, IR and H-1-NMR. Thc amphiphility spectrum and photochemical properties of 2 were reported.展开更多
The surface of a biowaste was modified by introduction of amino group for the purification of wastewater contaminated with heavy metals. In this study waste tea leaf was used as a biowaste which was an economic and ef...The surface of a biowaste was modified by introduction of amino group for the purification of wastewater contaminated with heavy metals. In this study waste tea leaf was used as a biowaste which was an economic and efficient bioadsorbent. The aminated tea leaves were characterized by spectral and elemental analysis. The adsorption capacity of the surface modified biosorbent was studied as the function of solution pH, concentration of metal ions and contact time of adsorption. The applicability of Langmuir isotherm was tested. The adsorption capacities were found to be 83.04 mg/g and 57 mg/g for Pb (II) and Cd (II), respectively. The biosorbent was regenerated by desorption of the metal loaded adsorbent with 0.1 M HNO3. These results showed that the aminated tea leaves may be an attractive alternative for treatment of wastewater contaminated with heavy metals.展开更多
Background:Nowadays,biodiesel has become more attractive in the quest for a novel fuel source due to its environmental benefits and the biodegradable properties.Transesterification of Helianthus annuus(sunflower)seeds...Background:Nowadays,biodiesel has become more attractive in the quest for a novel fuel source due to its environmental benefits and the biodegradable properties.Transesterification of Helianthus annuus(sunflower)seeds oil is one of methodsacci for producing biodiesel fuel.However,during this process,the impurities are frequently found in the synthesized biodiesel which degrades the quality of biodiesel.Therefore,a proper catalyst is required to obtain the high-quality biodiesel.In this study,a series of aminated polyethersulfone(PES-NH_(2))membranes was prepared as solid support for immobilized Mucor miehei lipase.Glutaraldehyde was used as a cross-linker agent in immobilization process to investigate the effect of spacer toward biodiesel production.Results:Based on elemental analysis,lipase was successfully attached onto PES-NH_(2)membranes and formed physical interactions.Enzyme loading values of synthesized membrane were higher than that of commercial filtration membrane.LC-MS analysis with C18 as a column showed that butyl palmitate,butyl linoleate,and butyl oleate were produced from transesterification reaction of triglyceride from sunflower oil and butanol.Based on FTIR analysis,the imine group as a covalent bond was successfully obtained during the cross-linking reaction.After reaction with the spacer,the enzyme loading was increased significantly from 177.05 to 911.48μg/cm^(2).The alkyl esters produced also showed high values after the cross-linking.According to biodiesel quality tests,the results were matched with the values specified by the ASTM.Conclusion:Biodiesel from sunflower seeds oil was successfully synthesized through a transesterification reaction catalyzed by Mucor miehei lipase immobilized onto the synthesized aminated PES membrane.The addition of glutaraldehyde as a cross-linker showed an excellent enzyme loading value and led to significantly increased biodiesel conversion efficiency.This method is good to be developed,since the immobilized enzyme stability could be increased,the separation process was easier,and a high yield with good quality of biodiesel could be obtained.展开更多
Graphene-mediated niches with excellent electroconductibility,good flexibility and convenient modification play a central role in manipulating the cardiogenesis of stem cells.Herein,the graphene derivative matrix of a...Graphene-mediated niches with excellent electroconductibility,good flexibility and convenient modification play a central role in manipulating the cardiogenesis of stem cells.Herein,the graphene derivative matrix of aminated graphene(G-NH_(2))was synthesized as a substrate niche to modulate cardiac differentiation of human induced pluripotent stem cells(hiPSCs).The conductivity of G-NH_(2) matrix was close to that of native myocardium while the surface roughness of G-NH_(2) matrix was much low to present a suitable interface for the adhesion of hiPSCs.The G-NH_(2) matrix effectively elevated the maturation of hiPSCs-derived cardiomyocytes based on the evaluation of cardiomyocyte contraction,sarcomere patterns and length,and the content of NCAD(N-cadherin).The molecular mechanism of cardiomyocyte maturation was highly associated with the signaling pathway of PDGF-β.The mature cardiomyocytes derived from G-NH_(2) were transplanted into the groin of immunodeficient mice to reveal the better survival and rapid angiogenesis.More importantly,in situ injection into rat hearts of differentiated mature cardiomyocytes exhibited the better performance on residence,survival and proliferation.Consequently,we created an instructive stem cell niche of G-NH_(2) matrix that can electrically stimulate various cellular behaviors of hiPSCs in vitro,and the enhanced maturation of hiPSCs-cardiomyocytes manifests favorable activity and function in vivo.展开更多
Herein,a Fe^(3+)-loaded aminated polypropylene fiber has been reported as an efficient phosphate adsorbent.The remarkable phosphate removal ability of the fiber is due to Fe^(3+)immobilization,and it demonstrates a ma...Herein,a Fe^(3+)-loaded aminated polypropylene fiber has been reported as an efficient phosphate adsorbent.The remarkable phosphate removal ability of the fiber is due to Fe^(3+)immobilization,and it demonstrates a maximum adsorption capacity of 33.94 mg·P·g^(–1).Adsorption experiments showed that the fiber is applicable over a wide pH range from 2 to 9.Furthermore,the adsorption kinetics and isotherm data were consistent with the pseudo-second-order and Langmuir adsorption models,respectively.The adsorption equilibrium of the fiber for phosphate was reached within 60 min,indicating an efficient monolayer chemisorption process.Moreover,the adsorbent maintained prominent phosphate removal in the presence of competitive ions such as NO_(3)^(–)and Cl^(–),exhibiting high selectivity.More importantly,the fiber demonstrated excellent reusability(5 times)and low adsorption limit below 0.02 mg·P·g^(–1).In addition,the phosphate removal efficiency of the fiber can exceed 99%under continuous flow conditions.The adsorption mechanism was studied by X-ray photoelectron spectroscopy,showing that the adsorption of phosphate on the fiber mainly depended on the chemical adsorption of the modified Fe^(3+).Overall,this study proves that the fiber possesses many advantages for phosphate removal,including high adsorption efficiency,lower treatment limit,good recyclability,and environmental friendliness.展开更多
Functional fullerene derivatives exhibit special inhibitory effects on tumor progress and metastasis via diverse tumor microenvironment regulations,while the elusive molecular mechanisms hinder their clinical transfor...Functional fullerene derivatives exhibit special inhibitory effects on tumor progress and metastasis via diverse tumor microenvironment regulations,while the elusive molecular mechanisms hinder their clinical transformation.Herein,it is initially revealed that nanosize aminated fullerene(C_(70)-EDA)can activate autophagic flux,induce G0/G1 cell cycle arrest to abrogate cancer cell proliferation,and significantly inhibit tumor growth in vivo.Mechanismly,C_(70)-EDA promotes the expression of cathepsin D involved in autophagic activation via post-transcriptional regulation,attributing to the interaction with a panel of RNA binding proteins.The accumulation of cathepsin D induces the autophagic degradation of cyclin D1,which arouses G0/G1 phase arrest.This work unveils the fantastic anti-tumor activity of aminated fullerene,elucidates the molecular mechanism,and provides a new strategy for the antineoplastic drug development on functional fullerenes.展开更多
Monitoring biogenic amines,which are metabolic byproducts of shrimp spoilage,is crucial for assessing food quality.Currently,most detection methods for biogenic amines suffer from limitations such as time-consuming pr...Monitoring biogenic amines,which are metabolic byproducts of shrimp spoilage,is crucial for assessing food quality.Currently,most detection methods for biogenic amines suffer from limitations such as time-consuming procedures,complex operations,and delayed results.Colorimetric analysis techniques have gained attention in recent years due to their advantages of short analysis time,simple operation,and suitability for on-site testing.This study successfully developed a series of colorimetric sensor platforms for biogenic amines by loading the natural active ingredient curcumin(CUR)and its derivative of Boron complex BFCUR onto filter paper and electrospun nanofibre films(ENFs),respectively.By analyzing the color response differences of these sensors upon contact with biogenic amines,the colorimetric sensors with superior detection performance were selected and further applied to the visual monitoring and indication of shrimp spoilage processes.展开更多
Chiral benzylic amines are important motifs in medicines.A dicationic nickel complex of chiral diphosphine(R)-Ph-BPE promotes highly enantioselective reductive amination of aryl alkyl ketones with arylamines using iso...Chiral benzylic amines are important motifs in medicines.A dicationic nickel complex of chiral diphosphine(R)-Ph-BPE promotes highly enantioselective reductive amination of aryl alkyl ketones with arylamines using isopropanol as hydrogen source.The reaction is easily scaled up in a gram-scale synthesis using 1 mol% nickel catalyst and it is applied to an asymmetric synthesis of(S)-rivastigmine.Building on this success,we achieved rare examples of asymmetric hydrogen borrowing reactions with arylamines using an Earth-abundant 3d metal,nickel.展开更多
Aqueous zinc-based batteries have emerged as promising candidates for large-scale energy storage owing to their inherent safety and cost-effectiveness.However,their widespread application is impeded by dendritic forma...Aqueous zinc-based batteries have emerged as promising candidates for large-scale energy storage owing to their inherent safety and cost-effectiveness.However,their widespread application is impeded by dendritic formation and parasitic reactions at zinc anodes.To address these issues,this study employs polyethyleneimine grafting and macropore filling to synergistically modify the cellulose separator.The zincophilic–NH_(2) and–NH–groups introduced by polyethyleneimine promote Zn^(2+)ion desolvation and nucleation processes.Concurrently,the nanocellulose incorporated into macropores not only significantly enhances mechanical properties but also compensates for macroporous defects within the cellulose separator.The optimized separator exhibits ultralow thickness(18μm),ultrahigh modulus(3.2 GPa),large ionic conductivity(19.0 mS cm^(-1)),high Zn^(2+)ion transfer number(0.63),and good biodegradability.Comprehensive experimental measurements and theoretical analysis reveal that the utilization of this separator contributes to significantly suppressed zinc dendrites and improved electrochemical kinetics.The assembled Zn//Zn cell demonstrates exceptional cycling stability(over 1000 h lifespan at10 m A cm^(-2)and 2 mAh cm^(-2)),and the Zn//MnO_(2) and Zn//I_(2) full batteries maintain excellent longterm cyclability under high cathode mass loadings.This work advances our understanding of multifunctional separator design for next-generation electrochemical energy storage systems.展开更多
This study investigated the suppressive effects of Armoracia rusticana(AR)and its three main glucosinolates on both free and bound heterocyclic amines(HAs),along with their mechanisms of free radical quenching using d...This study investigated the suppressive effects of Armoracia rusticana(AR)and its three main glucosinolates on both free and bound heterocyclic amines(HAs),along with their mechanisms of free radical quenching using density functional theory.Fish patties were supplemented with varying concentrations of AR(0.5%‒1.5%)and glucosinolates(0.005%‒0.015%),showing a dose-dependent inhibition of HAs and concurrent elimination of free radicals and HAs intermediates.Glucobrassicin demonstrated the highest reactivity,which was verified by frontier orbit analysis and conceptual density functional parameters,consistent with experimental findings.Furthermore,the O-H bond connected to the sulfur atom of glucobrassicin possessed the smallest bond dissociation enthalpy(BDE)value,which indicated that this particular hydrogen atom is most susceptible to react with free radicals.Overall,AR and its glucosinolates,especially glucobrassicin,show promise as natural additives for improving food safety and quality.展开更多
基金supported by the National Natural Science Foundation of China(22408161,21921006)the National Key Research and Development Program(2021YFB3801303)+1 种基金the Key Research and Development Program of Jiangsu Provincial Department of Science and Technology(BE2022033-3)the State Key Laboratory of Materials-Oriented Chemical Engineering(SKL-MCE-22A03)。
文摘Polymer fibers are among the most promising adsorbents in wastewater treatment,while limited by poor adsorption capacity and irreversible pollution.Herein,amine-modified C_(3)N_(4)/TiO_(2)-polyacrylonitrile(PAN)composite fibers with high absorption ability and photocatalytic self-cleaning properties were fabricated via wet spinning.The introduction of diethylenetriamine(DETA)onto the PAN resulted in the presence of positively charged amino groups,which not only increased the number of adsorption sites for anionic dyes but also facilitated the formation of a sponge-like pore structure.Optimally,the adsorption capacity of the aminated PAN fibers(PD7h)for methyl orange(MO)reached 164.79 mg·g^(-1),which is 39.2 times greater than that of unmodified PAN fibers.Furthermore,the introduction of the C_(3)N_(4)/TiO_(2) heterojunction photocatalyst endowed the fibers with photocatalytic self-cleaning capability by generating active free radicals(hydroxyl radicals(·OH)and superoxide radicals(·O_(2)^(-))that efficiently degraded dye pollutants in situ on the fiber surface.Under irradiation using a 300 W xenon lamp,the aminated C_(3)N_(4)/TiO_(2)^(-)PAN fibers(PDCT-1)removed more than 90%of MO(30 mg·L^(-1))within 120 min.After eight cycles,the pollutant removal rate decreased by only 22.41%,indicating excellent stability.Overall,this work presents an effective,simple and feasible method for preparing polymer fibers with high adsorption and photocatalytic self-cleaning properties via wet spinning for dye wastewater treatment.
基金Supported by Foundation of Minnan Normal University,the Funding(type A,No.JA11167)from the Fujian Education DepartmentNational Natural Science Foundation of China(31071518 and 31271837)+2 种基金Joint Specialized Research Fund for the Doctoral Program of Higher Education,MOE(20113515110010)Science and Technology Planning Project of technological department(2012GA7200022)Natural Science Foundation of Fujian Province(2011J01285)
文摘Konjac glucomannan （KGM） was aminated by 2-chloroethyl-amine （CEA） as reagent so as to study the influence of concentration of CEA （based on the amount of KGM）, concentration of NaOH, reaction time and temperature on the extent of amination. And the molecular simulation technology was adopted to analyze the conformation stability of aminate （AKGM）. The results indicate that when the amount of CEA is higher, the extent of amination is higher. The optimum concentration of NaOH, reaction time and temperature are 10% NaOH, 70 ℃ and 45 rain, respectively. IR shows KGM is successfully aminated. The conformation of AKGM is in a random clew-like shape.
基金supported by a grant of the French Agence Nationale de la Recherche(ANR)in the Ambit of the Laboratory of Excellence(Labex)ARBRE.This work was also supported by“The 111 Project(D21027)”.
文摘Aminated tannins were prepared by reacting mimosa condensed tannin extract with ammonia yielding the substitution of many,if not all of the tannin hydroxyl groups with–NH_(2)groups.A tannin-aminated tannin(ATT)particleboard coating was then prepared by reacting raw tannin extract with aminated tannin extract and thus cross-linking the two by substituting tannin’s hydroxyl groups with the–NH_(2)groups on the aminated tannin to form–NH-bridges between the two.The resulting particleboard coating gave encouraging results when pressed at 180℃for 3 min.Conversely,the system in which tannin was reacted/cross-liked with urea(ATU)by a similar amination reaction did not perform as well as the ATT system,and this even when a higher curing temperature and longer hot press time were used.In particular its water repellence was worse probably due to the presence of urea and such a system with lower reactivity.Nonetheless,substituting the tannin–OHs with the urea–NH_(2)groups appeared to also take place.ATT gave better results than ATU as regards water repellence and mechanical resistance as shown by the cross cut test.The ATT system was shown to be between 95%and 98%biosourced.The difference appeared to be due,by TMA analysis,to the much faster formation of the ATT hardened network leading to a better cross-linked polymer coating.The chemical species formed for both the ATT and ATU system were studied by MALDI ToF and CP MAS^(13)C NMR.
文摘An aminated hypercrosslinked macroporous polymeric adsorbent was synthesized and characterized. Adsorption isotherms for 1 amino 2 naphthol 4 sulfonic acid(1, 2, 4 acid) and 2 naphthol obtained from various binary adsorption environments can be well fitted by Freundlich equation, which indicated a favorable adsorption process in the studied range. Adsorption for 1, 2, 4 acid was an endothermic process in comparison with that for 2 naphthol of an exothermic process. 2 naphthol molecules put a little influence on the adsorption capacity for 1, 2, 4 acid. However, the adsorption to 1, 2, 4 acid depressed that to 2 naphthol in a large extent for the stronger electrostatic interaction between 1, 2, 4 acid and adsorbent. The predominant mechanism can be contributed to the competition for adsorption sites. And the simultaneous environment was confirmed to be helpful to the selective adsorption towards 1,2,4 acid based on the larger selectivity index.
文摘The new flow improvers for super-viscous crude oils were developed via esterification of polybasic high carbon alcohol with methacrylate and copolymerizafion of monomers followed by amination of copolymers. The structure of the synthesized polymer flow improver additive was confirmed by IR spectroscopy and the crystal structure of the flow improver additives were determined by X-ray diffrac- tion analysis. The structure of wax crystals was also studied at the same time. The results showed that the wax crystal structure was closely related with the crystal structure of the flow improver, which could change the pour point depression and viscosity reduction behavior of the crude oil. When the wax crystal structure matched well with that of the additive, the wax crystals were dispersed satisfactorily, resulting in favorable effects in terms of pour point depression and viscosity reduction. The new synthe- sized aminated polymer flow improver additive was most efficient for treating super-viscous crude oils. The super-viscous crude oil had a high content of resins and asphaltenes, which might aggregate onto the surface of wax crystals to form blocks to limit the crude oil fluidity. However, amination of copolymers having similar structure with the resins and asphaltenes contained in crude oil could dissolve the huge polar groups to make the deposit formation difficult.
文摘In the present study we prepared macroporous polyvinyl alcohol beads. A series of bilirubin adsorbents were generated by immobilization of eight amine agents to the beads as ligands. The adsorption of bilirubin was evaluated by in vitro static and dynamic adsorption tests. The results show that these adsorbents have excellent adsorption efficiency and capacity. Among the eight ligands, trimethylamine （TMA）, triethylamine （TEA） and 1,6- hexanediamine （HDA） showed the highest adsorption capacity. The adsorption equilibrium can be achieved in half an hour, and the adsorption percentage of bilirubin was up to 80%. Static electricity and hydrophobie interaction played the main role in bilirubin adsorption, and the adsorption was found to match the monolayer model. The excellent adsorption of these adsorbents indicates their potential in clinical treatment.
文摘Recently biospecific affinity chromatography has been widely used for the separation and purification of various enzymes and nucleic acids. In this paper, a series of synthetic reactions of solid-liquid phase were carried out on silica surface, using a macroporous(30 mu m), microspherical silica (8 mu m) as the matrix and gamma-aminopropyltriethoxysilane as the activating agent, the nicotinamide adenine dinucleotide(NAD) was bonded through its amino groups to the carboxylic groups of linked phospholipid which was bonded covalently on aminated support. The bonded stationary phase has high thermal stability, and could be used to separate of nucleotides with good resolution.
基金supported by the National Natural Science Foundation of China (No.51002090)the Outstanding Young Scientist Research Award Fund of Shandong Province (No.BS2010CL028)
文摘H-terminated DLC layers were synthesized on SiO 2 substrate by radio frequency (RF) magnetron plasma-enhanced chemical vapor deposition (PECVD) in a conventional reactor using C 4 H 10 as carbon source. As-deposited DLC films were characterized by Raman spectroscopy, scanning electron microscopy (SEM) as well as atomic force microscopy (AFM). The chemical reactivity of the obtained DLC surface was further investigated by exposing the photochemically oxidized DLC surface to a silane reagent. The course of the reaction was followed using water contact angle and X-ray photoelectron spectroscopy.
基金The authors are grateful for the financial support by the
文摘Peroxidase plays an important role in living systems;however,its storage difficulty and easy inactivation have limited its applications in complex environments.To address these problems,herein,we proposed a method to synthesize peroxidase mimics by amination,carbonization,and Fe^(3+)-doping of industrial alkali lignin.The Fe^(3+)-doped lignin-based peroxidase mimic(Fe-LPM),with active centers of coordination between Fe^(3+)and N atoms,showed higher tolerance to pH value and temperature than natural peroxidase.Using Fe-LPM,10-100 mmol/L of H_(2)O_(2) and glucose could be colorimetrically detected with the lowest detection limits of 80μmol/L and 1.5 mmol/L and visual detection limits of 1.0 mmol/L and 10 mmol/L,respectively.The Fe-LPM maintained peroxidase-like activity after 10 cycles and could even be used for H_(2)O_(2) detection in practical samples.This work not only provides a new approach to synthesize peroxidase mimics using biomass materials but also promotes the high-value utilization of lignin.
基金supported by the Research Project for Hot Tracking Items of Beijing Forestry University(2017BLRD03)the National Natural Science Foundation of China(51603012)+1 种基金the Special Science and Technology Research Program of Beijing Forestry University(2016KJ02)the Fundamental Research Funds for the Central Universities(BLYJ2016-17,BLX2015-06)
文摘A new method for the preparation of aminated lignin （AEL） through etherification and amination reaction was presented. Chlorine atoms were ？rstly introduced into lignin through its etheri？cation with epichlorohydrin. Then, hydrophilic amine groups were grafted to the modi？ed lignin structure through amination with ethylenediamine to obtain AEL. Subsequent acidi？cation of AEL led to the ionized aminated lignin （IAEL）. The results of our analyses showed that the nitrogen content of AEL was 6.9%. Foaming and emulsifying experiments indicated that AEL had better foamability and emulsifying properties than IAEL. Surface tension tests showed that AEL and IAEL had similar critical micelle concentration （CMC）. However, IAEL had lower surface tension （36.33 mN/m） than AEL （42.89 mN/m） at CMC. These results demonstrate the promising applicability of AEL as an emulsi？er and that of IAEL as feedstock in the production of detergent and dispersant.
基金the National Natural Science Foundation of China (Project No.39830090 and No.39970871) for their financial support to this resea
文摘A new aminated-perylenequinone derivative 2 was synthesized by the reaction of 1 (hypocrellin B) with 6-aminohexanoic-acid. The structure of 2 was identified by UV-Vis, MS, IR and H-1-NMR. Thc amphiphility spectrum and photochemical properties of 2 were reported.
文摘The surface of a biowaste was modified by introduction of amino group for the purification of wastewater contaminated with heavy metals. In this study waste tea leaf was used as a biowaste which was an economic and efficient bioadsorbent. The aminated tea leaves were characterized by spectral and elemental analysis. The adsorption capacity of the surface modified biosorbent was studied as the function of solution pH, concentration of metal ions and contact time of adsorption. The applicability of Langmuir isotherm was tested. The adsorption capacities were found to be 83.04 mg/g and 57 mg/g for Pb (II) and Cd (II), respectively. The biosorbent was regenerated by desorption of the metal loaded adsorbent with 0.1 M HNO3. These results showed that the aminated tea leaves may be an attractive alternative for treatment of wastewater contaminated with heavy metals.
文摘Background:Nowadays,biodiesel has become more attractive in the quest for a novel fuel source due to its environmental benefits and the biodegradable properties.Transesterification of Helianthus annuus(sunflower)seeds oil is one of methodsacci for producing biodiesel fuel.However,during this process,the impurities are frequently found in the synthesized biodiesel which degrades the quality of biodiesel.Therefore,a proper catalyst is required to obtain the high-quality biodiesel.In this study,a series of aminated polyethersulfone(PES-NH_(2))membranes was prepared as solid support for immobilized Mucor miehei lipase.Glutaraldehyde was used as a cross-linker agent in immobilization process to investigate the effect of spacer toward biodiesel production.Results:Based on elemental analysis,lipase was successfully attached onto PES-NH_(2)membranes and formed physical interactions.Enzyme loading values of synthesized membrane were higher than that of commercial filtration membrane.LC-MS analysis with C18 as a column showed that butyl palmitate,butyl linoleate,and butyl oleate were produced from transesterification reaction of triglyceride from sunflower oil and butanol.Based on FTIR analysis,the imine group as a covalent bond was successfully obtained during the cross-linking reaction.After reaction with the spacer,the enzyme loading was increased significantly from 177.05 to 911.48μg/cm^(2).The alkyl esters produced also showed high values after the cross-linking.According to biodiesel quality tests,the results were matched with the values specified by the ASTM.Conclusion:Biodiesel from sunflower seeds oil was successfully synthesized through a transesterification reaction catalyzed by Mucor miehei lipase immobilized onto the synthesized aminated PES membrane.The addition of glutaraldehyde as a cross-linker showed an excellent enzyme loading value and led to significantly increased biodiesel conversion efficiency.This method is good to be developed,since the immobilized enzyme stability could be increased,the separation process was easier,and a high yield with good quality of biodiesel could be obtained.
基金supported by the National Key Research and Development Program of China(2021YFA1101903,2022YFA1105100)the National Natural Science Foundation of China(32171323,91939111)+2 种基金Science,Technology,and Innovation Commission of Shenzhen Municipality(KCXFZ20211020164544008)DZwas funded by the Ministry of Science and Technology ofChina(National Science and Technology Major Project(2018YFA0109100)the National Natural ScienceFoundation of China(31871496)。
文摘Graphene-mediated niches with excellent electroconductibility,good flexibility and convenient modification play a central role in manipulating the cardiogenesis of stem cells.Herein,the graphene derivative matrix of aminated graphene(G-NH_(2))was synthesized as a substrate niche to modulate cardiac differentiation of human induced pluripotent stem cells(hiPSCs).The conductivity of G-NH_(2) matrix was close to that of native myocardium while the surface roughness of G-NH_(2) matrix was much low to present a suitable interface for the adhesion of hiPSCs.The G-NH_(2) matrix effectively elevated the maturation of hiPSCs-derived cardiomyocytes based on the evaluation of cardiomyocyte contraction,sarcomere patterns and length,and the content of NCAD(N-cadherin).The molecular mechanism of cardiomyocyte maturation was highly associated with the signaling pathway of PDGF-β.The mature cardiomyocytes derived from G-NH_(2) were transplanted into the groin of immunodeficient mice to reveal the better survival and rapid angiogenesis.More importantly,in situ injection into rat hearts of differentiated mature cardiomyocytes exhibited the better performance on residence,survival and proliferation.Consequently,we created an instructive stem cell niche of G-NH_(2) matrix that can electrically stimulate various cellular behaviors of hiPSCs in vitro,and the enhanced maturation of hiPSCs-cardiomyocytes manifests favorable activity and function in vivo.
基金This work was financially supported by the National Natural Science Foundation of China(Grant No.22208003)Natural Science Foundation of Anhui Province(No.1908085QB87)Major Science and Technology Projects in Anhui Province(No.202103a06020012).
文摘Herein,a Fe^(3+)-loaded aminated polypropylene fiber has been reported as an efficient phosphate adsorbent.The remarkable phosphate removal ability of the fiber is due to Fe^(3+)immobilization,and it demonstrates a maximum adsorption capacity of 33.94 mg·P·g^(–1).Adsorption experiments showed that the fiber is applicable over a wide pH range from 2 to 9.Furthermore,the adsorption kinetics and isotherm data were consistent with the pseudo-second-order and Langmuir adsorption models,respectively.The adsorption equilibrium of the fiber for phosphate was reached within 60 min,indicating an efficient monolayer chemisorption process.Moreover,the adsorbent maintained prominent phosphate removal in the presence of competitive ions such as NO_(3)^(–)and Cl^(–),exhibiting high selectivity.More importantly,the fiber demonstrated excellent reusability(5 times)and low adsorption limit below 0.02 mg·P·g^(–1).In addition,the phosphate removal efficiency of the fiber can exceed 99%under continuous flow conditions.The adsorption mechanism was studied by X-ray photoelectron spectroscopy,showing that the adsorption of phosphate on the fiber mainly depended on the chemical adsorption of the modified Fe^(3+).Overall,this study proves that the fiber possesses many advantages for phosphate removal,including high adsorption efficiency,lower treatment limit,good recyclability,and environmental friendliness.
基金This work was supported by the National Natural Science Foundation of China(No.51802310)All animal experiments were conducted according to protocols approved by the Institutional Animal Care and Use Committee in the Institute of Chemistry,Chinese Academy of Sciences.
文摘Functional fullerene derivatives exhibit special inhibitory effects on tumor progress and metastasis via diverse tumor microenvironment regulations,while the elusive molecular mechanisms hinder their clinical transformation.Herein,it is initially revealed that nanosize aminated fullerene(C_(70)-EDA)can activate autophagic flux,induce G0/G1 cell cycle arrest to abrogate cancer cell proliferation,and significantly inhibit tumor growth in vivo.Mechanismly,C_(70)-EDA promotes the expression of cathepsin D involved in autophagic activation via post-transcriptional regulation,attributing to the interaction with a panel of RNA binding proteins.The accumulation of cathepsin D induces the autophagic degradation of cyclin D1,which arouses G0/G1 phase arrest.This work unveils the fantastic anti-tumor activity of aminated fullerene,elucidates the molecular mechanism,and provides a new strategy for the antineoplastic drug development on functional fullerenes.
基金Supported by the Guangdong-Hong Kong-Macao Joint Laboratory on Micro-Nano Manufacturing Technology,China(No.2021LSYS004)Guangdong Provincial Key Laboratory of Sustainable Biomimetic Materials and Green Energy,China(No.2024B1212010003)。
文摘Monitoring biogenic amines,which are metabolic byproducts of shrimp spoilage,is crucial for assessing food quality.Currently,most detection methods for biogenic amines suffer from limitations such as time-consuming procedures,complex operations,and delayed results.Colorimetric analysis techniques have gained attention in recent years due to their advantages of short analysis time,simple operation,and suitability for on-site testing.This study successfully developed a series of colorimetric sensor platforms for biogenic amines by loading the natural active ingredient curcumin(CUR)and its derivative of Boron complex BFCUR onto filter paper and electrospun nanofibre films(ENFs),respectively.By analyzing the color response differences of these sensors upon contact with biogenic amines,the colorimetric sensors with superior detection performance were selected and further applied to the visual monitoring and indication of shrimp spoilage processes.
基金supported by the National Natural Science Foundation of China(Nos.22271007,W2431014)Peking University Shenzhen Graduate School+2 种基金State Key Laboratory of Chemical OncogenomicsShenzhen Key Laboratory of Chemical GenomicsShenzhen Bay Laboratory.
文摘Chiral benzylic amines are important motifs in medicines.A dicationic nickel complex of chiral diphosphine(R)-Ph-BPE promotes highly enantioselective reductive amination of aryl alkyl ketones with arylamines using isopropanol as hydrogen source.The reaction is easily scaled up in a gram-scale synthesis using 1 mol% nickel catalyst and it is applied to an asymmetric synthesis of(S)-rivastigmine.Building on this success,we achieved rare examples of asymmetric hydrogen borrowing reactions with arylamines using an Earth-abundant 3d metal,nickel.
基金the financial support from the Natural Science Foundation of Jiangsu Province(BK20231292)the Jiangsu Agricultural Science and Technology Innovation Fund(CX(24)3091)+7 种基金the National Key R&D Program of China(2024YFE0109200)the Fundamental Research Funds for the Central Universities(No.2024300440)the Guangdong Basic and Applied Basic Research Foundation(2025A1515011098)the Postgraduate Research&Practice Innovation Program of Jiangsu Province(KYCX24_1299)the National Natural Science Foundation of China(12464032)the Natural Science Foundation of Jiangxi Province(20232BAB201032)the Ji’an Science and Technology Plan Project(2024H-100301)supported by the high-performance computing campus level public platform of Jinggangshan University。
文摘Aqueous zinc-based batteries have emerged as promising candidates for large-scale energy storage owing to their inherent safety and cost-effectiveness.However,their widespread application is impeded by dendritic formation and parasitic reactions at zinc anodes.To address these issues,this study employs polyethyleneimine grafting and macropore filling to synergistically modify the cellulose separator.The zincophilic–NH_(2) and–NH–groups introduced by polyethyleneimine promote Zn^(2+)ion desolvation and nucleation processes.Concurrently,the nanocellulose incorporated into macropores not only significantly enhances mechanical properties but also compensates for macroporous defects within the cellulose separator.The optimized separator exhibits ultralow thickness(18μm),ultrahigh modulus(3.2 GPa),large ionic conductivity(19.0 mS cm^(-1)),high Zn^(2+)ion transfer number(0.63),and good biodegradability.Comprehensive experimental measurements and theoretical analysis reveal that the utilization of this separator contributes to significantly suppressed zinc dendrites and improved electrochemical kinetics.The assembled Zn//Zn cell demonstrates exceptional cycling stability(over 1000 h lifespan at10 m A cm^(-2)and 2 mAh cm^(-2)),and the Zn//MnO_(2) and Zn//I_(2) full batteries maintain excellent longterm cyclability under high cathode mass loadings.This work advances our understanding of multifunctional separator design for next-generation electrochemical energy storage systems.
基金supported by the National Natural Science Foundation of China(32302258,32172317)the Science and Technology Innovation Program of Hunan Province(2024RC3185)+1 种基金Hunan Provincial Natural Science Foundation of China(2023JJ40317)Changsha Municipal Natural Science Foundation(kq2202223).
文摘This study investigated the suppressive effects of Armoracia rusticana(AR)and its three main glucosinolates on both free and bound heterocyclic amines(HAs),along with their mechanisms of free radical quenching using density functional theory.Fish patties were supplemented with varying concentrations of AR(0.5%‒1.5%)and glucosinolates(0.005%‒0.015%),showing a dose-dependent inhibition of HAs and concurrent elimination of free radicals and HAs intermediates.Glucobrassicin demonstrated the highest reactivity,which was verified by frontier orbit analysis and conceptual density functional parameters,consistent with experimental findings.Furthermore,the O-H bond connected to the sulfur atom of glucobrassicin possessed the smallest bond dissociation enthalpy(BDE)value,which indicated that this particular hydrogen atom is most susceptible to react with free radicals.Overall,AR and its glucosinolates,especially glucobrassicin,show promise as natural additives for improving food safety and quality.
