A pair of carboxy-cyclobutane isomers were synthesized stereoselectively using a method that combined reversible amide bond formation and self-assembly of coordination polymers(CPs)via solid-state photochemical[2+2]cy...A pair of carboxy-cyclobutane isomers were synthesized stereoselectively using a method that combined reversible amide bond formation and self-assembly of coordination polymers(CPs)via solid-state photochemical[2+2]cycloaddition reactions.Amide bond formation occurred by the condensation of amino and carboxy groups to prepare a pyridine-amide ligand,while pyridine-amide CPs were constructed by the self-assembly of metal ions,pyridine-amide,and auxiliary ligands for the solid-state[2+2]photodimerization during the second step.The pyridine-amide ligand underwent the[2+2]cycloaddition reaction in 2D CPs to generate amide-cyclobutane derivatives stereoselectively that were afforded by removing metal ions and auxiliary ligands under alkaline conditions.The carboxy-cyclobutane isomers were successfully synthesized by the hydrolysis of the amide-cyclobutane derivatives.Moreover,the second amide-cyclobutane derivative and carboxy-cyclobutane derivative were obtained stereoselectively via regulating the reaction site of[2+2]cycloaddition by introducing a substituent group in the auxiliary ligand.展开更多
文摘A pair of carboxy-cyclobutane isomers were synthesized stereoselectively using a method that combined reversible amide bond formation and self-assembly of coordination polymers(CPs)via solid-state photochemical[2+2]cycloaddition reactions.Amide bond formation occurred by the condensation of amino and carboxy groups to prepare a pyridine-amide ligand,while pyridine-amide CPs were constructed by the self-assembly of metal ions,pyridine-amide,and auxiliary ligands for the solid-state[2+2]photodimerization during the second step.The pyridine-amide ligand underwent the[2+2]cycloaddition reaction in 2D CPs to generate amide-cyclobutane derivatives stereoselectively that were afforded by removing metal ions and auxiliary ligands under alkaline conditions.The carboxy-cyclobutane isomers were successfully synthesized by the hydrolysis of the amide-cyclobutane derivatives.Moreover,the second amide-cyclobutane derivative and carboxy-cyclobutane derivative were obtained stereoselectively via regulating the reaction site of[2+2]cycloaddition by introducing a substituent group in the auxiliary ligand.
