A pair of new enantiomeric furoquinoline alkaloids,(±)-zanthonitidine A(1),together with nine known ones(2-10)were isolated from the radix of Zanthoxylum nitidum.Their chemical structures were elucidated based on...A pair of new enantiomeric furoquinoline alkaloids,(±)-zanthonitidine A(1),together with nine known ones(2-10)were isolated from the radix of Zanthoxylum nitidum.Their chemical structures were elucidated based on the extensive spectroscopic analysis.The racemic mixture of 1 was separated by chiral column chromatography,and the absolute configurations of (+)-1 and(-)-1 were determined by the comparison of experimental and calculated electronic circular dichroism spectra.Antibacterial activities of compounds 1-9 were evaluated,and compounds(+)-1,(-)-1,3,7 and 8 showed antibacterial activities against Bacillus subtilis,Enterococcus faecalis or Staphylococcus aureus.展开更多
Objective:To investigate various phytochemical constituents present in pod and seed of Crotalaria incana L.(C.incana).Methods:A number of phytochemical tests were applied to identify the class of compounds in the CH_(...Objective:To investigate various phytochemical constituents present in pod and seed of Crotalaria incana L.(C.incana).Methods:A number of phytochemical tests were applied to identify the class of compounds in the CH_(2)C_(l2)/CH_(3)OH(1:1)pod and seed extract of C.incana.Results:Phytochemical screening of the CH_(2)C_(l2)/CH_(3)OH(1:1)pod and seed extract of C.incana subsp.purpurscens revealed that the presence of alkaloids,flavonoids,terpenoids,tannins and stroids.Conclusions:The present work conducted on the CH_(2)Cl_(2):CH_(3)OH(1:1)pod and seed extract of C.incana identified various classes of compounds present on the pod and seed extract.展开更多
基金supported by the National Natural Science Foundation of China(31470428,21702231)the National New Drug Innovation Major Project of China(2017ZX09309027)the Program for Jiangsu Province Innovative Research Team,the Fund for Introduction of High-level Talents from China Pharmaceu-tical University and the Fundamental Research Funds for the Central Universities(2632017PY19).
文摘A pair of new enantiomeric furoquinoline alkaloids,(±)-zanthonitidine A(1),together with nine known ones(2-10)were isolated from the radix of Zanthoxylum nitidum.Their chemical structures were elucidated based on the extensive spectroscopic analysis.The racemic mixture of 1 was separated by chiral column chromatography,and the absolute configurations of (+)-1 and(-)-1 were determined by the comparison of experimental and calculated electronic circular dichroism spectra.Antibacterial activities of compounds 1-9 were evaluated,and compounds(+)-1,(-)-1,3,7 and 8 showed antibacterial activities against Bacillus subtilis,Enterococcus faecalis or Staphylococcus aureus.
基金Supported by Debre Tabor University,Ethiopia(Grant No.DTU/596/Nc-03/07).
文摘Objective:To investigate various phytochemical constituents present in pod and seed of Crotalaria incana L.(C.incana).Methods:A number of phytochemical tests were applied to identify the class of compounds in the CH_(2)C_(l2)/CH_(3)OH(1:1)pod and seed extract of C.incana.Results:Phytochemical screening of the CH_(2)C_(l2)/CH_(3)OH(1:1)pod and seed extract of C.incana subsp.purpurscens revealed that the presence of alkaloids,flavonoids,terpenoids,tannins and stroids.Conclusions:The present work conducted on the CH_(2)Cl_(2):CH_(3)OH(1:1)pod and seed extract of C.incana identified various classes of compounds present on the pod and seed extract.
