A novel reaction of trimethylsilylated arylacetylenes with sulfonyl chlorides was performed in the presence of silver nitrate or triflate. Conjugated vinyl sulfones as dramatic products were obtained in moderate yield...A novel reaction of trimethylsilylated arylacetylenes with sulfonyl chlorides was performed in the presence of silver nitrate or triflate. Conjugated vinyl sulfones as dramatic products were obtained in moderate yields and with Z-selectivity. A free radical mechanism has been proposed to account for the formation of the products.展开更多
The nucleophilic ring opening reaction of propargyl epoxides by amines based on a silver catalyst is presented, The reaction takes place under mild conditions and features a high regioselectivity to provide an effecti...The nucleophilic ring opening reaction of propargyl epoxides by amines based on a silver catalyst is presented, The reaction takes place under mild conditions and features a high regioselectivity to provide an effective method for the synthesis of 2-amino homopropargyl alcohols in moderate to high yields,展开更多
An operationally simple approach for the tandem synthesis of isoquinolines by the reaction of o-alkynylalde- hydes with ammonium bicarbonate via Ag-catalyzed 6-endo-dig ring closure is described. The reaction conditio...An operationally simple approach for the tandem synthesis of isoquinolines by the reaction of o-alkynylalde- hydes with ammonium bicarbonate via Ag-catalyzed 6-endo-dig ring closure is described. The reaction conditions and the scope of the reaction are examined, and a variety of substituted isoquinolines are prepared in moderate to excellent yields.展开更多
文摘A novel reaction of trimethylsilylated arylacetylenes with sulfonyl chlorides was performed in the presence of silver nitrate or triflate. Conjugated vinyl sulfones as dramatic products were obtained in moderate yields and with Z-selectivity. A free radical mechanism has been proposed to account for the formation of the products.
基金the National Natural Science Foundation of China(No. 21302095)Research Fund for the Doctoral Program of Higher Education of China(No. 20133221120003)+2 种基金Jiangsu Provincial NSFC(Nos. BK20130945, BK20130924)Top-notch Academic Programs Project of Jiangsu Higher Education Institutions (TAPP)Nanjing Tech University for financial support
文摘The nucleophilic ring opening reaction of propargyl epoxides by amines based on a silver catalyst is presented, The reaction takes place under mild conditions and features a high regioselectivity to provide an effective method for the synthesis of 2-amino homopropargyl alcohols in moderate to high yields,
基金The generous financial support from the National Natural Science Foundation of China （Nos. 21372070 and 21471052） and the Hunan Provincial Education Department Scientific Research Fund （No. 14k035） are gratefully acknowledged.
文摘An operationally simple approach for the tandem synthesis of isoquinolines by the reaction of o-alkynylalde- hydes with ammonium bicarbonate via Ag-catalyzed 6-endo-dig ring closure is described. The reaction conditions and the scope of the reaction are examined, and a variety of substituted isoquinolines are prepared in moderate to excellent yields.
