In the Indian Himalayan Region, th studies focused on diversity of the plants used fo treating liver diseases/ailments have not been carried out so far. Therefore, the present attempt has been made to study the divers...In the Indian Himalayan Region, th studies focused on diversity of the plants used fo treating liver diseases/ailments have not been carried out so far. Therefore, the present attempt has been made to study the diversity, distribution pattern and conservation status of the plant species used fo treating liver diseases/ailments in that region. A tota of 138 species (35 species of trees, 22 shrubs and 8 herbs) belonging to 98 genera in 60 families hav been recorded. Amongst the families, Euphorbiacea (9 species), and altitudinal zone <1,800 m, (i.e., 11 species) are rich in species. Traditionally, variou plant parts, such as roots/rhizomes/tubers (46 species), leaves (31), whole plants (30), barks (15) fruits (13), seeds and unspecified parts (8 each), and inflorescence (1) are used for the treatment of live diseases/ailments. 34 species are native, 3 ar endemic and 15 near endemic. 7 species ar categorized as Critically Endangered (Betula utilis) Endangered (Podophyllum hexandrum, Ephedra gerardiana, and Nardostachys grandiflora) and Vulnerable (Bergenia ligulata, B. stracheyi, and Hedychium spicatum) using new IUCN criteria Available chemical composition of plant parts used fo the treatment of liver diseases/ailments have beengiven. Assessment of the populations of threatened species, development of an appropriate strategy, action plan for the conservation and sustainable utilization of such components of plant diversity are suggested.展开更多
Today,liver disease,or any deterioration in one’s ability to survive,is extremely common all around the world.Previous research has indicated that liver disease is more frequent in younger people than in older ones.W...Today,liver disease,or any deterioration in one’s ability to survive,is extremely common all around the world.Previous research has indicated that liver disease is more frequent in younger people than in older ones.When the liver’s capability begins to deteriorate,life can be shortened to one or two days,and early prediction of such diseases is difficult.Using several machine learning(ML)approaches,researchers analyzed a variety of models for predicting liver disorders in their early stages.As a result,this research looks at using the Random Forest(RF)classifier to diagnose the liver disease early on.The dataset was picked from the University of California,Irvine repository.RF’s accomplishments are contrasted to those of Multi-Layer Perceptron(MLP),Average One Dependency Estimator(A1DE),Support Vector Machine(SVM),Credal Decision Tree(CDT),Composite Hypercube on Iterated Random Projection(CHIRP),K-nearest neighbor(KNN),Naïve Bayes(NB),J48-Decision Tree(J48),and Forest by Penalizing Attributes(Forest-PA).Some of the assessment measures used to evaluate each classifier include Root Relative Squared Error(RRSE),Root Mean Squared Error(RMSE),accuracy,recall,precision,specificity,Matthew’s Correlation Coefficient(MCC),F-measure,and G-measure.RF has an RRSE performance of 87.6766 and an RMSE performance of 0.4328,however,its percentage accuracy is 72.1739.The widely acknowledged result of this work can be used as a starting point for subsequent research.As a result,every claim that a new model,framework,or method enhances forecastingmay be benchmarked and demonstrated.展开更多
Medicinal plants play a major role in meeting people’s medical and health needs, especially in developing countries. However, due to a lack of access to modern veterinary facilities, poor visibility of animal health ...Medicinal plants play a major role in meeting people’s medical and health needs, especially in developing countries. However, due to a lack of access to modern veterinary facilities, poor visibility of animal health personnel, and high prices of orthodox medicines, most farmers rely on traditional healers and the administration of medicinal plants to treat livestock ailments. The present study was conducted to document Ethnopharmacological knowledge of medicinal plants used to manage livestock ailments in three rural communities of the Eastern Cape. This study was carried out in three rural communities between July 2009 and February 2010. Data were collected by administering pre-tested semi-structured questionnaires and participative field observations. For the interviews, a sample of 48 knowledgeable respondents was purposively selected. Data were analyzed using descriptive and inferential statistics, determination of information consensus factor, and fidelity level. A total of 12 medicinal plants belonging to 9 families were used by local people to cure different ailments. A high number of medicinal plants were claimed by males compared to females. Roots and barks were the major plant parts used, and the least were leaves (27.3%). Six plants were used to treat diarrhea and fertility, five plants to treat wounds, and two plants to treat scabs. This study has shown that Eastern Cape flora is rich with various plants which could be used to replace orthodox drugs. Further studies are needed to determine the minimum inhibitory concentrations, biological activities, and toxicities and characterize the plant’s chemical compounds.展开更多
Regardless of the high value of medicinal plants to residents of Cross River State in health maintenance especially for the treatment of “ailments of utmost native importance”, the major constraint is the uncertaint...Regardless of the high value of medicinal plants to residents of Cross River State in health maintenance especially for the treatment of “ailments of utmost native importance”, the major constraint is the uncertainty of the availability of the herbs and knowledge of traditional medicine still being passed by word of mouth. For better reliance on the plant species as medicine, this research seek</span><span style="font-family:Verdana;">s</span><span style="font-family:""><span style="font-family:Verdana;"> to identify and infer on the population and distribution of the species used in their treatment and documents them. Data were collected using field work and oral interviews. The survey team comprised of Taxonom</span><span style="font-family:Verdana;">ists, survey assistants, five trado-medical herbal practitioners and the Auth</span><span style="font-family:Verdana;">ors. </span><span style="font-family:Verdana;">The status and geographical distribution of the identified medicinal plant sp</span><span style="font-family:Verdana;">ecies was appalling, 59 percent of the medicinal plant species were distributed in 3 out of 15 sampled plots. Causal factors included over misuse of therapeu</span><span style="font-family:Verdana;">tic plant species, habitats destruction and absence of proper conservation ed</span><span style="font-family:Verdana;">ucation of the masses. Recommendations are that Communities should set up therapeutic plants farms, enrichment planting be made in agricultural fields and sustainable harvesting methods used.展开更多
Background:Eosinophilic extracellular traps(EETs)are reticular complexes comprising deoxyribonucleic-Acid(DNA)fibers and granule proteins.Aims:EETs play a crucial role in antimicrobial host responses and are pathogeni...Background:Eosinophilic extracellular traps(EETs)are reticular complexes comprising deoxyribonucleic-Acid(DNA)fibers and granule proteins.Aims:EETs play a crucial role in antimicrobial host responses and are pathogenic when overproduced or under degraded.EETs created by eosinophils appear to enable vital immune responses against extra-cellular pathogens,nevertheless,trap overproduction is evident in pathology.Materials&Methods:As considerably research is performed,new data affirmed that EETs can alter the outcome of respiratory ailment.Results:We probe into the disclosure and specificity of EETs produced in reaction to various stimuli and propose a role for those frameworks in ailment pathogenesis and the establishment of chronic,unresolved inflammation.Discussion:Whether EETs can be used as a prospective brand-new target for the diagnosis,treatment and prognosis of respiratory ailments is a scientific theme worth studying.Conclusion:We probe into the disclosure and specificity of EETs produced in reaction to various stimuli and propose a role for those frameworks in ailment pathogenesis and the establishment of chronic,unresolved inflammation.展开更多
Chemical tests were carried out on the aqueous extracts of the air-dried powders of two tropical moss plants, Thidium gratum and Barbula indica using standard procedures, to identify the phytochemical constituents. Th...Chemical tests were carried out on the aqueous extracts of the air-dried powders of two tropical moss plants, Thidium gratum and Barbula indica using standard procedures, to identify the phytochemical constituents. The extracts were screened for the presence and quantities of alkaloids, flavonoids, phenols, saponins and steroids with a view to assess their therapeutic values in ethnomedicine. The results of the phytochemical screening revealed the presence of alkaloids, flavonoids, phenols, saponins and steroids in varying quantities in the two moss plants but there was absence of phenol in Barbula indica. These results suggest that the two moss plants can be veritable and potential source of useful drugs in treatment of ailments.展开更多
文摘In the Indian Himalayan Region, th studies focused on diversity of the plants used fo treating liver diseases/ailments have not been carried out so far. Therefore, the present attempt has been made to study the diversity, distribution pattern and conservation status of the plant species used fo treating liver diseases/ailments in that region. A tota of 138 species (35 species of trees, 22 shrubs and 8 herbs) belonging to 98 genera in 60 families hav been recorded. Amongst the families, Euphorbiacea (9 species), and altitudinal zone <1,800 m, (i.e., 11 species) are rich in species. Traditionally, variou plant parts, such as roots/rhizomes/tubers (46 species), leaves (31), whole plants (30), barks (15) fruits (13), seeds and unspecified parts (8 each), and inflorescence (1) are used for the treatment of live diseases/ailments. 34 species are native, 3 ar endemic and 15 near endemic. 7 species ar categorized as Critically Endangered (Betula utilis) Endangered (Podophyllum hexandrum, Ephedra gerardiana, and Nardostachys grandiflora) and Vulnerable (Bergenia ligulata, B. stracheyi, and Hedychium spicatum) using new IUCN criteria Available chemical composition of plant parts used fo the treatment of liver diseases/ailments have beengiven. Assessment of the populations of threatened species, development of an appropriate strategy, action plan for the conservation and sustainable utilization of such components of plant diversity are suggested.
基金the support of the Deputy for Research and Innovation-Ministry of Education,Kingdom of Saudi Arabia for this research at Najran University,Kingdom of Saudi Arabiathe support of the Deputy for Research and Innovation-Ministry of Education,Kingdom of Saudi Arabia for this research through a grant(NU/IFC/ENT/01/014)under the institutional Funding Committee at Najran University,Kingdom of Saudi Arabia.
文摘Today,liver disease,or any deterioration in one’s ability to survive,is extremely common all around the world.Previous research has indicated that liver disease is more frequent in younger people than in older ones.When the liver’s capability begins to deteriorate,life can be shortened to one or two days,and early prediction of such diseases is difficult.Using several machine learning(ML)approaches,researchers analyzed a variety of models for predicting liver disorders in their early stages.As a result,this research looks at using the Random Forest(RF)classifier to diagnose the liver disease early on.The dataset was picked from the University of California,Irvine repository.RF’s accomplishments are contrasted to those of Multi-Layer Perceptron(MLP),Average One Dependency Estimator(A1DE),Support Vector Machine(SVM),Credal Decision Tree(CDT),Composite Hypercube on Iterated Random Projection(CHIRP),K-nearest neighbor(KNN),Naïve Bayes(NB),J48-Decision Tree(J48),and Forest by Penalizing Attributes(Forest-PA).Some of the assessment measures used to evaluate each classifier include Root Relative Squared Error(RRSE),Root Mean Squared Error(RMSE),accuracy,recall,precision,specificity,Matthew’s Correlation Coefficient(MCC),F-measure,and G-measure.RF has an RRSE performance of 87.6766 and an RMSE performance of 0.4328,however,its percentage accuracy is 72.1739.The widely acknowledged result of this work can be used as a starting point for subsequent research.As a result,every claim that a new model,framework,or method enhances forecastingmay be benchmarked and demonstrated.
文摘Medicinal plants play a major role in meeting people’s medical and health needs, especially in developing countries. However, due to a lack of access to modern veterinary facilities, poor visibility of animal health personnel, and high prices of orthodox medicines, most farmers rely on traditional healers and the administration of medicinal plants to treat livestock ailments. The present study was conducted to document Ethnopharmacological knowledge of medicinal plants used to manage livestock ailments in three rural communities of the Eastern Cape. This study was carried out in three rural communities between July 2009 and February 2010. Data were collected by administering pre-tested semi-structured questionnaires and participative field observations. For the interviews, a sample of 48 knowledgeable respondents was purposively selected. Data were analyzed using descriptive and inferential statistics, determination of information consensus factor, and fidelity level. A total of 12 medicinal plants belonging to 9 families were used by local people to cure different ailments. A high number of medicinal plants were claimed by males compared to females. Roots and barks were the major plant parts used, and the least were leaves (27.3%). Six plants were used to treat diarrhea and fertility, five plants to treat wounds, and two plants to treat scabs. This study has shown that Eastern Cape flora is rich with various plants which could be used to replace orthodox drugs. Further studies are needed to determine the minimum inhibitory concentrations, biological activities, and toxicities and characterize the plant’s chemical compounds.
文摘Regardless of the high value of medicinal plants to residents of Cross River State in health maintenance especially for the treatment of “ailments of utmost native importance”, the major constraint is the uncertainty of the availability of the herbs and knowledge of traditional medicine still being passed by word of mouth. For better reliance on the plant species as medicine, this research seek</span><span style="font-family:Verdana;">s</span><span style="font-family:""><span style="font-family:Verdana;"> to identify and infer on the population and distribution of the species used in their treatment and documents them. Data were collected using field work and oral interviews. The survey team comprised of Taxonom</span><span style="font-family:Verdana;">ists, survey assistants, five trado-medical herbal practitioners and the Auth</span><span style="font-family:Verdana;">ors. </span><span style="font-family:Verdana;">The status and geographical distribution of the identified medicinal plant sp</span><span style="font-family:Verdana;">ecies was appalling, 59 percent of the medicinal plant species were distributed in 3 out of 15 sampled plots. Causal factors included over misuse of therapeu</span><span style="font-family:Verdana;">tic plant species, habitats destruction and absence of proper conservation ed</span><span style="font-family:Verdana;">ucation of the masses. Recommendations are that Communities should set up therapeutic plants farms, enrichment planting be made in agricultural fields and sustainable harvesting methods used.
基金Department of Otolaryngological,Shanghai Changzheng Hospital,Grant/Award Number:0907National ScienceFoundationof China,Grant/Award Numbers:81541038,81670905,81870702。
文摘Background:Eosinophilic extracellular traps(EETs)are reticular complexes comprising deoxyribonucleic-Acid(DNA)fibers and granule proteins.Aims:EETs play a crucial role in antimicrobial host responses and are pathogenic when overproduced or under degraded.EETs created by eosinophils appear to enable vital immune responses against extra-cellular pathogens,nevertheless,trap overproduction is evident in pathology.Materials&Methods:As considerably research is performed,new data affirmed that EETs can alter the outcome of respiratory ailment.Results:We probe into the disclosure and specificity of EETs produced in reaction to various stimuli and propose a role for those frameworks in ailment pathogenesis and the establishment of chronic,unresolved inflammation.Discussion:Whether EETs can be used as a prospective brand-new target for the diagnosis,treatment and prognosis of respiratory ailments is a scientific theme worth studying.Conclusion:We probe into the disclosure and specificity of EETs produced in reaction to various stimuli and propose a role for those frameworks in ailment pathogenesis and the establishment of chronic,unresolved inflammation.
文摘Chemical tests were carried out on the aqueous extracts of the air-dried powders of two tropical moss plants, Thidium gratum and Barbula indica using standard procedures, to identify the phytochemical constituents. The extracts were screened for the presence and quantities of alkaloids, flavonoids, phenols, saponins and steroids with a view to assess their therapeutic values in ethnomedicine. The results of the phytochemical screening revealed the presence of alkaloids, flavonoids, phenols, saponins and steroids in varying quantities in the two moss plants but there was absence of phenol in Barbula indica. These results suggest that the two moss plants can be veritable and potential source of useful drugs in treatment of ailments.
