目的探究医科达Agility多叶准直器直线加速器在调强放射治疗计划中的剂量学优势。方法选择采用Monaco系统的30例肿瘤患者,其中男性14例,女性16例;年龄44~69岁,平均年龄58岁;肿瘤类型,头部肿瘤5例,颈部肿瘤5例,胸部肿瘤5例,乳腺癌5例,腹...目的探究医科达Agility多叶准直器直线加速器在调强放射治疗计划中的剂量学优势。方法选择采用Monaco系统的30例肿瘤患者,其中男性14例,女性16例;年龄44~69岁,平均年龄58岁;肿瘤类型,头部肿瘤5例,颈部肿瘤5例,胸部肿瘤5例,乳腺癌5例,腹部肿瘤5例,盆腔肿瘤5例。先用MLCi2多叶准直器进行放射治疗设计(MLCi2 MLC计划)。不改变计划,再用Agility多叶准直器进行放射治疗设计(Agility MLC计划)。加速器升级成Agility多叶准直器前后调强放射治疗计划的适形度指数、均匀性指数及各类危及器官剂量的差异性进行比较。结果不同放射治疗设计下,30例癌症患者计划靶区的均匀性指数(0.13±0.07 vs 0.10±0.05)和适形度指数(0.73±0.17 vs 0.75±0.13),腹部肿瘤患者计划靶区的均匀性指数(0.12±0.09 vs 0.09±0.03)和适形度指数(0.78±0.05 vs 0.81±0.06),以及肺(V20)[(23.53±11.80)cm^(3)vs(20.85±9.23)cm^(3)]、小肠(D_(max))[(5344.67±407.89)cGy vs(5244.76±361.13)cGy]、腮腺(V_(50))[(18.34±7.72)cm^(3)vs(12.23±10.27)cm^(3)]重要危及器官差异具有统计学意义(P<0.05)。Agility多叶准直器会产生大量的孤岛野,孤岛野达到总射野数的50.0%、52.3%、55.6%,孤岛野会大幅度提高双靶区患者的靶区适形度和均匀性。结论Agility多叶准直器对肿瘤的调强放射治疗计划的靶区均匀性和危及器官的保护限制均具有优势,尤其针对腹部肿瘤和双靶区患者。展开更多
Purpose: The primary aim of this study was to develop an assessment of the fundamental, combined, and complex movement skills required to support childhood physical literacy. The secondary aim was to establish the fea...Purpose: The primary aim of this study was to develop an assessment of the fundamental, combined, and complex movement skills required to support childhood physical literacy. The secondary aim was to establish the feasibility, objectivity, and reliability evidence for the assessment.Methods: An expert advisory group recommended a course format for the assessment that would require children to complete a series of dynamic movement skills. Criterion-referenced skill performance and completion time were the recommended forms of evaluation. Children, 8–12 years of age, self-reported their age and gender and then completed the study assessments while attending local schools or day camps. Face validity was previously established through a Delphi expert(n = 19, 21% female) review process. Convergent validity was evaluated by age and gender associations with assessment performance. Inter-and intra-rater(n = 53, 34% female) objectivity and test–retest(n = 60, 47% female) reliability were assessed through repeated test administration.Results: Median total score was 21 of 28 points(range 5–28). Median completion time was 17 s. Total scores were feasible for all 995 children who self-reported age and gender. Total score did not differ between inside and outside environments(95% confidence interval(CI) of difference:-0.7 to 0.6;p = 0.91) or with/without footwear(95%CI of difference:-2.5 to 1.9; p = 0.77). Older age(p < 0.001, η2= 0.15) and male gender(p < 0.001, η2= 0.02)were associated with a higher total score. Inter-rater objectivity evidence was excellent(intraclass correlation coefficient(ICC) = 0.99) for completion time and substantial for skill score(ICC = 0.69) for 104 attempts by 53 children(34% female). Intra-rater objectivity was moderate(ICC = 0.52) for skill score and excellent for completion time(ICC = 0.99). Reliability was excellent for completion time over a short(2–4 days; ICC = 0.84) or long(8–14days; ICC = 0.82) interval. Skill score reliability was moderate(ICC = 0.46) over a short interval, and substantial(ICC = 0.74) over a long interval.Conclusion: The Canadian Agility and Movement Skill Assessment is a feasible measure of selected fundamental, complex and combined movement skills, which are an important building block for childhood physical literacy. Moderate-to-excellent objectivity was demonstrated for children 8–12 years of age. Test–retest reliability has been established over an interval of at least 1 week. The time and skill scores can be accurately estimated by 1 trained examiner.展开更多
Purpose： The aim of this study was to assess the effects of combining the FIFA 11＋ and acute vibration training on reactive strength index （RSI） and 505 agility. Methods： Seventy-four male collegiate soccer playe...Purpose： The aim of this study was to assess the effects of combining the FIFA 11＋ and acute vibration training on reactive strength index （RSI） and 505 agility. Methods： Seventy-four male collegiate soccer players took part in the study and were randomly assigned to FIFA 11＋ with acute vibration group （FIFA ＋ WBV）, FIFA 11＋ with isometric squat group （FIFA ＋ IS） or a control group consisting of the F1FA 11＋ alone （Con）. The warm-up consisted of the FIFA 11＋ and was administered to all participants. The participants in the acute vibration group were exposed to 30 s whole body vibration in squat position immediately post warm-up. The isometric group completed an isometric squat for 30 s immediately post warm-up. Results： RSI significantly improved pre- to post-intervention amongst FIFA ＋ WBV （p 〈 0.001） due to a decrease in contact time （p 〈 0.001） in comparison to FIFA ＋ IS and Con, but 505 agility was not affected. Conclusion： The results of this study suggest the inclusion of an acute bout of WBV post FIFA 11＋ warm-up produces a neuromuscular response leading to an improvement in RSI. Future research is required to examine the exact mechanisms behind these improvements amongst other populations and over time course of the performance.展开更多
The purpose of this paper is to calculate the torsional agility metric,the time-to-roll and capture a 90° bank angle change,using a simple pilot mathematical model obtained from simulator test. The metric mention...The purpose of this paper is to calculate the torsional agility metric,the time-to-roll and capture a 90° bank angle change,using a simple pilot mathematical model obtained from simulator test. The metric mentioned above is determined by the aircraft maneuverability and controllability,or the pilot ability to roll and capture quickly and accurately a bank angle. Therefore, the time-to-roll and capture a 90° bank angle change can be obtained by calculating the open loop process with limited maximum stick denflect velocity and the man-machine closed loop precise tracking control. Results show that the calculated values are quite consistent with the manned simulation data. The dteterioration of torsional agility while the aircraft is poor or very maneuverable can be explained. It is suggested that this approach could provide the basis for the approxi mate evaluation of aircraft torsional agility metric.展开更多
Modeling plays an important role in understanding and implementation of manufacturing system under changing competitive environment. Agile manuincturing is a new pattern of production. It is the issue to identify, ana...Modeling plays an important role in understanding and implementation of manufacturing system under changing competitive environment. Agile manuincturing is a new pattern of production. It is the issue to identify, analyze and evaluate agility for involved people, information,process and organization. There is no commonly accepted analytical structure. The essence of agility is investigated and a model to develop agility is elucidated.展开更多
Agility metrics are difficult to define in general, mainly due to the multidimensionality and vagueness of the concept of agility itself. In this paper, a knowledge-based framework is utilized for the measurement and ...Agility metrics are difficult to define in general, mainly due to the multidimensionality and vagueness of the concept of agility itself. In this paper, a knowledge-based framework is utilized for the measurement and assessment of public sector＇s agility by A. T. Kearney model. In this research, the authors used Z2 test in SPSS software. So, the authors discovered that the General Office of Standards ＆ Industrial Research of Sistan ＆ Baluchestan Province in Iran is agile. Finally, the authors determine the weakness points of organization by Friedman test.展开更多
Emerging technologies and innovative developments cause the supply chain management to change dramatically. Therefore the subjects regarding trust have become important. Trust established in Supply Chain causes effect...Emerging technologies and innovative developments cause the supply chain management to change dramatically. Therefore the subjects regarding trust have become important. Trust established in Supply Chain causes effective relationships among definitive numbers of suppliers in the long-run. The effect of trust in supply chain on firm performance and the contribution of agility to this relation have been supported in the literature. In this research, the role of agility in the effect of trust in supply chain on firm performance will be investigated. According to the results of hypotheses tests, there are positive and significant relations between supply management integration and trust in supply chain, between trust in supply chain and supply chain agility, and between supply chain agility and firm performance.展开更多
In the last decade, turbulent times and uncertainti es in the business environment have made ground for a new business era, and "chang e" has become a major characteristic of the new era. This has resulted i...In the last decade, turbulent times and uncertainti es in the business environment have made ground for a new business era, and "chang e" has become a major characteristic of the new era. This has resulted in tirele ss evolution of business systems and the creation of new manufacturing and manag ement philosophies. Agile Manufacturing (AM) is a step forward in generation of new means for better performance and success of business, and in practice is a s trategic approach to manufacturing by considering the new conditions of the business environment. This paper discusses the concepts and development of a met hodology to achieve agility in manufacturing organisations. Following an introdu ction of the subject of agility, a discussion of the methodology and practical t ools to support the implementation of the methodology, including metrics for the assessment of agility drivers, capability and performance are given. Aspects of the tools are tested in an aerospace company.展开更多
Enterprise competition tends to be a topic of much significance in society with gradual development, especially when there exist hundreds and thousands of production and business activities of the establishment in cur...Enterprise competition tends to be a topic of much significance in society with gradual development, especially when there exist hundreds and thousands of production and business activities of the establishment in current world. The enterprise must attach much importance to market so as to be in superiority and satisfy the needs of the broad masses of customers. This thesis shall propose the marketing mode of agility in marketing for many establishments hence the increase in competitiveness of enterprises and existence in the whole society.展开更多
Mass Customization (MC) is one of the importance en te rprise produces modes in information age progressively. Mass Customization produ ct manufacturing is aimed at the objection of agile responding to customer deman ...Mass Customization (MC) is one of the importance en te rprise produces modes in information age progressively. Mass Customization produ ct manufacturing is aimed at the objection of agile responding to customer deman d, market changing and market opportunities to combine with modern management te chnology and advanced manufacture technology, and to use the development model o f design for product family and technology concurrent. Therefore, in the environ ment of market continuing to change with a high speed, MC enterprise is required to raise its ability of controlling future market by improving its "agility of product manufacturing". So it is necessary to research about the question of agi lity evaluation of MC product manufacturing. Base on the characteristics of the Mass Customization (MC) product manufacturing and the requirement of the agile m anufacturing, this paper establish an MC product manufacturing Agility evaluatio n index system through studying MC enterprise’s organization management agility evaluation and MC products design agility evaluation and MC manufacture agility evaluation. Also, with Xi Dian Casting limited company as an example, the multi -grade fuzzy assessment method is used to evaluate its agility.展开更多
The agility of production planning is defined as two characters： synchronization and flexibility. Measurement indexes for evaluating agility are then divided into two dimensions separately. Synchronization includes t...The agility of production planning is defined as two characters： synchronization and flexibility. Measurement indexes for evaluating agility are then divided into two dimensions separately. Synchronization includes two horizontal indexes： order lead time ratio and demand fulfilling rate; Two vertical indexes： instruction-reaction cycle time and resource matching rate. Flexibility includes five indexes： scope flexibility, delivery flexibility, variety flexibility, capacity buffer, inventory buffer and modification flexibility. Quantitative formulas for each measurement index are constructed. One application is discussed to illustrate the feasibility and reasonability of the indexes.展开更多
文摘目的探究医科达Agility多叶准直器直线加速器在调强放射治疗计划中的剂量学优势。方法选择采用Monaco系统的30例肿瘤患者,其中男性14例,女性16例;年龄44~69岁,平均年龄58岁;肿瘤类型,头部肿瘤5例,颈部肿瘤5例,胸部肿瘤5例,乳腺癌5例,腹部肿瘤5例,盆腔肿瘤5例。先用MLCi2多叶准直器进行放射治疗设计(MLCi2 MLC计划)。不改变计划,再用Agility多叶准直器进行放射治疗设计(Agility MLC计划)。加速器升级成Agility多叶准直器前后调强放射治疗计划的适形度指数、均匀性指数及各类危及器官剂量的差异性进行比较。结果不同放射治疗设计下,30例癌症患者计划靶区的均匀性指数(0.13±0.07 vs 0.10±0.05)和适形度指数(0.73±0.17 vs 0.75±0.13),腹部肿瘤患者计划靶区的均匀性指数(0.12±0.09 vs 0.09±0.03)和适形度指数(0.78±0.05 vs 0.81±0.06),以及肺(V20)[(23.53±11.80)cm^(3)vs(20.85±9.23)cm^(3)]、小肠(D_(max))[(5344.67±407.89)cGy vs(5244.76±361.13)cGy]、腮腺(V_(50))[(18.34±7.72)cm^(3)vs(12.23±10.27)cm^(3)]重要危及器官差异具有统计学意义(P<0.05)。Agility多叶准直器会产生大量的孤岛野,孤岛野达到总射野数的50.0%、52.3%、55.6%,孤岛野会大幅度提高双靶区患者的靶区适形度和均匀性。结论Agility多叶准直器对肿瘤的调强放射治疗计划的靶区均匀性和危及器官的保护限制均具有优势,尤其针对腹部肿瘤和双靶区患者。
基金funded by a grant from the Canadian Institutes of Health Research awarded to Dr. Meghann Lloyd and Dr. Mark Tremblay (IHD 94356)
文摘Purpose: The primary aim of this study was to develop an assessment of the fundamental, combined, and complex movement skills required to support childhood physical literacy. The secondary aim was to establish the feasibility, objectivity, and reliability evidence for the assessment.Methods: An expert advisory group recommended a course format for the assessment that would require children to complete a series of dynamic movement skills. Criterion-referenced skill performance and completion time were the recommended forms of evaluation. Children, 8–12 years of age, self-reported their age and gender and then completed the study assessments while attending local schools or day camps. Face validity was previously established through a Delphi expert(n = 19, 21% female) review process. Convergent validity was evaluated by age and gender associations with assessment performance. Inter-and intra-rater(n = 53, 34% female) objectivity and test–retest(n = 60, 47% female) reliability were assessed through repeated test administration.Results: Median total score was 21 of 28 points(range 5–28). Median completion time was 17 s. Total scores were feasible for all 995 children who self-reported age and gender. Total score did not differ between inside and outside environments(95% confidence interval(CI) of difference:-0.7 to 0.6;p = 0.91) or with/without footwear(95%CI of difference:-2.5 to 1.9; p = 0.77). Older age(p < 0.001, η2= 0.15) and male gender(p < 0.001, η2= 0.02)were associated with a higher total score. Inter-rater objectivity evidence was excellent(intraclass correlation coefficient(ICC) = 0.99) for completion time and substantial for skill score(ICC = 0.69) for 104 attempts by 53 children(34% female). Intra-rater objectivity was moderate(ICC = 0.52) for skill score and excellent for completion time(ICC = 0.99). Reliability was excellent for completion time over a short(2–4 days; ICC = 0.84) or long(8–14days; ICC = 0.82) interval. Skill score reliability was moderate(ICC = 0.46) over a short interval, and substantial(ICC = 0.74) over a long interval.Conclusion: The Canadian Agility and Movement Skill Assessment is a feasible measure of selected fundamental, complex and combined movement skills, which are an important building block for childhood physical literacy. Moderate-to-excellent objectivity was demonstrated for children 8–12 years of age. Test–retest reliability has been established over an interval of at least 1 week. The time and skill scores can be accurately estimated by 1 trained examiner.
文摘Purpose： The aim of this study was to assess the effects of combining the FIFA 11＋ and acute vibration training on reactive strength index （RSI） and 505 agility. Methods： Seventy-four male collegiate soccer players took part in the study and were randomly assigned to FIFA 11＋ with acute vibration group （FIFA ＋ WBV）, FIFA 11＋ with isometric squat group （FIFA ＋ IS） or a control group consisting of the F1FA 11＋ alone （Con）. The warm-up consisted of the FIFA 11＋ and was administered to all participants. The participants in the acute vibration group were exposed to 30 s whole body vibration in squat position immediately post warm-up. The isometric group completed an isometric squat for 30 s immediately post warm-up. Results： RSI significantly improved pre- to post-intervention amongst FIFA ＋ WBV （p 〈 0.001） due to a decrease in contact time （p 〈 0.001） in comparison to FIFA ＋ IS and Con, but 505 agility was not affected. Conclusion： The results of this study suggest the inclusion of an acute bout of WBV post FIFA 11＋ warm-up produces a neuromuscular response leading to an improvement in RSI. Future research is required to examine the exact mechanisms behind these improvements amongst other populations and over time course of the performance.
文摘The purpose of this paper is to calculate the torsional agility metric,the time-to-roll and capture a 90° bank angle change,using a simple pilot mathematical model obtained from simulator test. The metric mentioned above is determined by the aircraft maneuverability and controllability,or the pilot ability to roll and capture quickly and accurately a bank angle. Therefore, the time-to-roll and capture a 90° bank angle change can be obtained by calculating the open loop process with limited maximum stick denflect velocity and the man-machine closed loop precise tracking control. Results show that the calculated values are quite consistent with the manned simulation data. The dteterioration of torsional agility while the aircraft is poor or very maneuverable can be explained. It is suggested that this approach could provide the basis for the approxi mate evaluation of aircraft torsional agility metric.
文摘Modeling plays an important role in understanding and implementation of manufacturing system under changing competitive environment. Agile manuincturing is a new pattern of production. It is the issue to identify, analyze and evaluate agility for involved people, information,process and organization. There is no commonly accepted analytical structure. The essence of agility is investigated and a model to develop agility is elucidated.
文摘Agility metrics are difficult to define in general, mainly due to the multidimensionality and vagueness of the concept of agility itself. In this paper, a knowledge-based framework is utilized for the measurement and assessment of public sector＇s agility by A. T. Kearney model. In this research, the authors used Z2 test in SPSS software. So, the authors discovered that the General Office of Standards ＆ Industrial Research of Sistan ＆ Baluchestan Province in Iran is agile. Finally, the authors determine the weakness points of organization by Friedman test.
文摘Emerging technologies and innovative developments cause the supply chain management to change dramatically. Therefore the subjects regarding trust have become important. Trust established in Supply Chain causes effective relationships among definitive numbers of suppliers in the long-run. The effect of trust in supply chain on firm performance and the contribution of agility to this relation have been supported in the literature. In this research, the role of agility in the effect of trust in supply chain on firm performance will be investigated. According to the results of hypotheses tests, there are positive and significant relations between supply management integration and trust in supply chain, between trust in supply chain and supply chain agility, and between supply chain agility and firm performance.
文摘In the last decade, turbulent times and uncertainti es in the business environment have made ground for a new business era, and "chang e" has become a major characteristic of the new era. This has resulted in tirele ss evolution of business systems and the creation of new manufacturing and manag ement philosophies. Agile Manufacturing (AM) is a step forward in generation of new means for better performance and success of business, and in practice is a s trategic approach to manufacturing by considering the new conditions of the business environment. This paper discusses the concepts and development of a met hodology to achieve agility in manufacturing organisations. Following an introdu ction of the subject of agility, a discussion of the methodology and practical t ools to support the implementation of the methodology, including metrics for the assessment of agility drivers, capability and performance are given. Aspects of the tools are tested in an aerospace company.
文摘Enterprise competition tends to be a topic of much significance in society with gradual development, especially when there exist hundreds and thousands of production and business activities of the establishment in current world. The enterprise must attach much importance to market so as to be in superiority and satisfy the needs of the broad masses of customers. This thesis shall propose the marketing mode of agility in marketing for many establishments hence the increase in competitiveness of enterprises and existence in the whole society.
文摘Mass Customization (MC) is one of the importance en te rprise produces modes in information age progressively. Mass Customization produ ct manufacturing is aimed at the objection of agile responding to customer deman d, market changing and market opportunities to combine with modern management te chnology and advanced manufacture technology, and to use the development model o f design for product family and technology concurrent. Therefore, in the environ ment of market continuing to change with a high speed, MC enterprise is required to raise its ability of controlling future market by improving its "agility of product manufacturing". So it is necessary to research about the question of agi lity evaluation of MC product manufacturing. Base on the characteristics of the Mass Customization (MC) product manufacturing and the requirement of the agile m anufacturing, this paper establish an MC product manufacturing Agility evaluatio n index system through studying MC enterprise’s organization management agility evaluation and MC products design agility evaluation and MC manufacture agility evaluation. Also, with Xi Dian Casting limited company as an example, the multi -grade fuzzy assessment method is used to evaluate its agility.
基金This project is supported by National Natural Science Foundation of China (No.70271023).
文摘The agility of production planning is defined as two characters： synchronization and flexibility. Measurement indexes for evaluating agility are then divided into two dimensions separately. Synchronization includes two horizontal indexes： order lead time ratio and demand fulfilling rate; Two vertical indexes： instruction-reaction cycle time and resource matching rate. Flexibility includes five indexes： scope flexibility, delivery flexibility, variety flexibility, capacity buffer, inventory buffer and modification flexibility. Quantitative formulas for each measurement index are constructed. One application is discussed to illustrate the feasibility and reasonability of the indexes.
