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Dispatchable Capability of Aggregated Electric Vehicle Charging in Distribution Systems 被引量:1
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作者 Shiqian Wang Bo Liu +4 位作者 Yuanpeng Hua Qiuyan Li Binhua Tang Jianshu Zhou Yue Xiang 《Energy Engineering》 EI 2025年第1期129-152,共24页
This paper introduces a method for modeling the entire aggregated electric vehicle(EV)charging process and analyzing its dispatchable capabilities.The methodology involves developing a model for aggregated EV charging... This paper introduces a method for modeling the entire aggregated electric vehicle(EV)charging process and analyzing its dispatchable capabilities.The methodology involves developing a model for aggregated EV charging at the charging station level,estimating its physical dispatchable capability,determining its economic dispatchable capability under economic incentives,modeling its participation in the grid,and investigating the effects of different scenarios and EV penetration on the aggregated load dispatch and dispatchable capability.The results indicate that using economic dispatchable capability reduces charging prices by 9.7%compared to physical dispatchable capability and 9.3%compared to disorderly charging.Additionally,the peak-to-valley difference is reduced by 64.6%when applying economic dispatchable capability with 20%EV penetration and residential base load,compared to disorderly charging. 展开更多
关键词 aggregated charging dispatchable capability peak shaving and valley filling the economics of charging demand response
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Multiagent,multitimescale aggregated regulation method for demand response considering spatial-temporal complementarity of user-side resources
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作者 Tingzhe Pan Chao Li +3 位作者 Chen Yang Zijie Meng Zongyi Wang Zean Zhu 《Global Energy Interconnection》 2025年第2期240-257,共18页
The integration of substantial renewable energy and controllable resources disrupts the supply-demand balance in distribution grids.Secure operations are dependent on the participation of user-side resources in demand... The integration of substantial renewable energy and controllable resources disrupts the supply-demand balance in distribution grids.Secure operations are dependent on the participation of user-side resources in demand response at both the day-ahead and intraday levels.Current studies typically overlook the spatial--temporal variations and coordination between these timescales,leading to significant day-ahead optimization errors,high intraday costs,and slow convergence.To address these challenges,we developed a multiagent,multitimescale aggregated regulation method for spatial--temporal coordinated demand response of user-side resources.Firstly,we established a framework considering the spatial--temporal coordinated characteristics of user-side resources with the objective to min-imize the total regulation cost and weighted sum of distribution grid losses.The optimization problem was then solved for two different timescales:day-ahead and intraday.For the day-ahead timescale,we developed an improved particle swarm optimization(IPSO)algo-rithm that dynamically adjusts the number of particles based on intraday outcomes to optimize the regulation strategies.For the intraday timescale,we developed an improved alternating direction method of multipliers(IADMM)algorithm that distributes tasks across edge distribution stations,dynamically adjusting penalty factors by using historical day-ahead data to synchronize the regulations and enhance precision.The simulation results indicate that this method can fully achieve multitimescale spatial--temporal coordinated aggregated reg-ulation between day-ahead and intraday,effectively reduce the total regulation cost and distribution grid losses,and enhance smart grid resilience. 展开更多
关键词 Demand response User-side resources aggregated regulation Multitimescale Multiagent spatial--temporal coordination
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Assessing the capacity value of demand flexibility from aggregated small Internet data centers in power distribution systems
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作者 Bo Zeng Xinzhu Xu Fulin Yang 《Global Energy Interconnection》 2025年第3期460-473,共14页
With the advent of the digital economy,there has been a rapid proliferation of small-scale Internet data centers(SIDCs).By leveraging their spatiotemporal load regulation potential through data workload balancing,aggr... With the advent of the digital economy,there has been a rapid proliferation of small-scale Internet data centers(SIDCs).By leveraging their spatiotemporal load regulation potential through data workload balancing,aggregated SIDCs have emerged as promising demand response(DR)resources for future power distribution systems.This paper presents an innovative framework for assessing capacity value(CV)by aggregating SIDCs participating in DR programs(SIDC-DR).Initially,we delineate the concept of CV tailored for aggregated SIDC scenarios and establish a metric for the assessment.Considering the effects of the data load dynamics,equipment constraints,and user behavior,we developed a sophisticated DR model for aggregated SIDCs using a data network aggregation method.Unlike existing studies,the proposed model captures the uncertainties associated with end tenant decisions to opt into an SIDC-DR program by utilizing a novel uncertainty modeling approach called Z-number formulation.This approach accounts for both the uncertainty in user participation intentions and the reliability of basic information during the DR process,enabling high-resolution profiling of the SIDC-DR potential in the CV evaluation.Simulation results from numerical studies conducted on a modified IEEE-33 node distribution system confirmed the effectiveness of the proposed approach and highlighted the potential benefits of SIDC-DR utilization in the efficient operation of future power systems. 展开更多
关键词 aggregated Small internet data center Demand response Capacity value Z-number
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CONSERVATIVE ESTIMATING FUNCTION IN THE NONLINEAR REGRESSION MODEL WITH AGGREGATED DATA 被引量:1
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作者 林路 《Acta Mathematica Scientia》 SCIE CSCD 2000年第3期335-340,共6页
The purpose of this paper is to study the theory of conservative estimating functions in nonlinear regression model with aggregated data. In this model, a quasi-score function with aggregated data is defined. When thi... The purpose of this paper is to study the theory of conservative estimating functions in nonlinear regression model with aggregated data. In this model, a quasi-score function with aggregated data is defined. When this function happens to be conservative, it is projection of the true score function onto a class of estimation functions. By constructing, the potential function for the projected score with aggregated data is obtained, which have some properties of log-likelihood function. 展开更多
关键词 nonlinear regression model with aggregated data quasi-score function conservative vector field potential function
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Wavelet-Aggregated Signal in Earthquake Prediction 被引量:1
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作者 A.A.Lyubushin Jr 《Earthquake Research in China》 1999年第1期35-45,共11页
The concept of aggregated signal is introduced. Quantitatively, an aggregated signal can be defined as the scalar signal: it accumulates in its own variations only those spectral components that are presented simultan... The concept of aggregated signal is introduced. Quantitatively, an aggregated signal can be defined as the scalar signal: it accumulates in its own variations only those spectral components that are presented simultaneously in each scalar time series of the multidimensional signal to be analyzed. Moreover, an algorithm of aggregation is proposed to suppress the spectral components that are present in any of the scalar components but absent in others (these components can be called local disturbance signals, for instance of technogenic nature). The main purpose of constructing the aggregated signal is to make clearer the common tendency of low-frequency data-flow in geophysical networks, which indicates an increase in collective behavior.It is known that almost all models of the process of earthquake preparation have pointed out an increase in collective behavior of components of geophysical fields in the region of preparation when the coming geocatastrophe has entered its long- and mid-term stages. 展开更多
关键词 MULTI-DIMENSIONAL time series analysis aggregated SIGNALS wavelets.
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THE INFLUENCE OF HEAT TREATMENT ON STRUCTURES OF THE AGGREGATED STATE OF POLYAMIDE-1010
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作者 张宏放 杨宝泉 莫志深 《Chinese Journal of Polymer Science》 SCIE CAS CSCD 1996年第4期318-323,共6页
The structural parameters of the aggregated state of polyamide (PA)-1010 annealed at various temperatures were computed by means of the desmearing intensity from Smalt Angle X-ray Scattering (SAXS) measurements and by... The structural parameters of the aggregated state of polyamide (PA)-1010 annealed at various temperatures were computed by means of the desmearing intensity from Smalt Angle X-ray Scattering (SAXS) measurements and by using the concept of the distance distribution function. The results indicated that the structural parameters of the aggregated state were strongly dependent upon heat treatment conditions and the maximum values of the structural parameters were obtained for the samples annealed at T = 175 degrees C. The particle size Z annealed at different temperature was ranged between 8.1-12.8nm, and the values of the distance distribution function P-max(Z) were obtained when Z = 4.0-6.8 nm. Using one dimension electron density correlation function (1D EDCF) method long period (L) and thickness of the lamellar (d(0)) were estimated and were found to increase with the increase of the degree of crystallinity. 展开更多
关键词 polyamide-1010 SAXS heat treatment structure of aggregated state
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Grain erosion wear properties and grinding performance of porous aggregated cubic boron nitride abrasive wheels
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作者 Biao ZHAO Xin WANG +4 位作者 Wenfeng DING Yang WANG Yucan FU Yanjun ZHAO Jianhui ZHU 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2023年第6期446-459,共14页
Cubic boron nitride(cBN)superabrasive grinding wheels exhibit unique advantages in the grinding of difficult-to-cut materials with high strength and toughness,such as titanium alloys and superalloys.However,grinding w... Cubic boron nitride(cBN)superabrasive grinding wheels exhibit unique advantages in the grinding of difficult-to-cut materials with high strength and toughness,such as titanium alloys and superalloys.However,grinding with multilayered metallic cBN superabrasive wheels faces problems in terms of grain wear resistance,the chip storage capability of the working layers and the stability and controllability of the dressing process.Therefore,in this work,novel metallic cBN superabrasive wheels with aggregated cBN(AcBN)grains and open pore structures were fabricated to improve machining efficiency and surface quality.Prior to the grinding trials,the airborne abrasive blasting process was conducted and the abrasive blasting parameters were optimized in view of wear properties of cBN grains and metallic matrix materials.Subsequently,the comparative experiments were performed and then the variations in grinding force and force ratio,grinding temperature,tool wear morphology and ground surface quality of the multilayered AcBN grinding wheels were investigated during machining Ti-6Al-4V alloys.In consideration of the variations of grain erosion wear volume and material removal rate per unit of pure metallic matrix materials as the abrasive blasting parameters changes,the optimal abrasive blasting parameters were identified as the SiC abrasive mesh size of 60#and the abrasive blasting distance and time of 60 mm and 15 s,respectively.The as-developed AcBN grains exhibited better fracture toughness and impact resistance than monocrystalline cBN(McBN)grains because of the existence of metal-bonded materials amongst multiple cBN particles that decreased crack propagation inside whole grains.The metallic porous AcBN wheels had lower grinding forces and temperature and better ground surface quality than vitrified McBN wheels due to the constant layer-by-layer exposure of cBN particles in the working layer of AcBN wheels. 展开更多
关键词 Air-borne abrasive blasting aggregated cBN abrasive grains Grinding performance Ground surface quality Self-sharpening ability
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A Method for Directly Counting and Quantitatively Comparing Aggregated Structures during Cluster Formation
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作者 Xi Yang Zhong-yuan Lu 《Chinese Journal of Chemical Physics》 SCIE CAS CSCD 2021年第2期137-148,I0001,共13页
Assembling of a few particles into a cluster commonly occurs in many systems.However,it is still challenging to precisely control particle assembling,due to the various amorphous structures induced by thermal fluctuat... Assembling of a few particles into a cluster commonly occurs in many systems.However,it is still challenging to precisely control particle assembling,due to the various amorphous structures induced by thermal fluctuations during cluster formation.Although these structures may have very different degrees of aggregation,a quantitative method is lacking to describe them,and how these structures evolve remains unclear.Therefore a significant step towards precise control of particle self-assembly is to describe and analyze various aggregation structures during cluster formation quantitatively.In this work,we are motivated to propose a method to directly count and quantitatively compare different aggregated structures.We also present several case studies to evaluate how the aggregated structures during cluster formation are affected by external controlling factors,e.g.,different interaction ranges,interaction strengths,or anisotropy of attraction. 展开更多
关键词 SELF-ASSEMBLY Cluster formation aggregated structures Quantitative analysis
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On use of the alpha stable self-similar stochastic process to model aggregated VBR video traffic
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作者 Huang Tianyun 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2006年第3期677-684,共8页
The alpha stable self-similar stochastic process has been proved an effective model for high variable data traffic. A deep insight into some special issues and considerations on use of the process to model aggregated ... The alpha stable self-similar stochastic process has been proved an effective model for high variable data traffic. A deep insight into some special issues and considerations on use of the process to model aggregated VBR video traffic is made. Different methods to estimate stability parameter a and self-similar parameter H are compared. Processes to generate the linear fractional stable noise (LFSN) and the alpha stable random variables are provided. Model construction and the quantitative comparisons with fractional Brown motion (FBM) and real traffic are also examined. Open problems and future directions are also given with thoughtful discussions. 展开更多
关键词 network modeling alpha stable self-similar process aggregated VBR video traffic long range dependence VARIABILITY linear regression.
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Resonance Raman Study of Aggregated Meso-tetra(4-pyridinium)porphyrin Diacid
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作者 李遵云 卢同同 +2 位作者 何天敬 刘凡镇 陈东明 《Chinese Journal of Chemical Physics》 SCIE CAS CSCD 2009年第4期346-352,447,共8页
Resonance Raman spectra of aggregated meso-tetra(4-pyridinium)porphyrin diacid (H8TPyP^6+) were studied with excitation near the exciton absorption bands of 470 nm. The UV-Vis absorption and resonance light scatt... Resonance Raman spectra of aggregated meso-tetra(4-pyridinium)porphyrin diacid (H8TPyP^6+) were studied with excitation near the exciton absorption bands of 470 nm. The UV-Vis absorption and resonance light scattering spectra of HsTPyP^6+ monomers and aggregates were also measured. The observed Raman bands of monomeric and aggregated HsTPyP^6+ were assigned on the basis of the observed deuteration shifts and by comparing with the Raman spectra of analogous porphyrin diacids. Aggregation causes moderate downshifts (2-6 cm^-1) for high-frequency modes involving the in-plane CC/CN stretches of the porphyrin core and a dramatic upshift (12 cm^-1) for the out-of-plane saddling mode of the porphyrin ring. The structural changes induced by aggregation and the possible hydrogen bonding interaction between the HsTPyP^6+ molecules in the aggregate are discussed based on the spectral observations. 展开更多
关键词 Porphyrin diacid AGGREGATE Resonance Raman Molecular vibration
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Aggregated morphodynamic modelling of tidal inlets and estuaries 被引量:1
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作者 Zheng Bing Wang Ian Townend Marcel Stive 《Water Science and Engineering》 EI CAS CSCD 2020年第1期1-13,共13页
Aggregation is used to represent the real world in a model at an appropriate level of abstraction.We used the convection-diffusion equation to examine the implications of aggregation progressing from a three-dimension... Aggregation is used to represent the real world in a model at an appropriate level of abstraction.We used the convection-diffusion equation to examine the implications of aggregation progressing from a three-dimensional(3D)spatial description to a model representing a system as a single box that exchanges sediment with the adjacent environment.We highlight how all models depend on some forms of parametric closure,which need to be chosen to suit the scale of aggregation adopted in the model.All such models are therefore aggregated and make use of some empirical relationships to deal with sub-scale processes.One such appropriately aggregated model,the model for the aggregated scale morphological interaction between tidal basin and adjacent coast(ASMITA),is examined in more detail and used to illustrate the insight that this level of aggregation can bring to a problem by considering how tidal inlets and estuaries are impacted by sea level rise. 展开更多
关键词 TIDAL INLET and ESTUARY Morphodynamic modelling AGGREGATION Temporal and spatial scales Sea level RISE SEDIMENT transport
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COMMUNITY ANALYSIS OF AGGREGATED BACTERIA IN SOUTHERN LAKE BAIKAL
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作者 Ahn T.S. Kim O.S. +1 位作者 Spiglazov L.P Drucker V.V 《水生生物学报》 CAS CSCD 北大核心 2006年第6期718-720,共3页
[KG(0.01mm]This study focuses on the community structure of aggregated bacteria in Lake Baikal and relationships with free-living bacteria. Fluorescent in situ hybridization (FISH) methods were used in samples of bact... [KG(0.01mm]This study focuses on the community structure of aggregated bacteria in Lake Baikal and relationships with free-living bacteria. Fluorescent in situ hybridization (FISH) methods were used in samples of bacteria taken in April, 2001. Bacterial counts of free-living bacteria by DAPI staining ranged from 0.2×10 6 to 3.2×10 6 cells·mL -1, decreasing with depth, whereas aggregated bacterial numbers dramatically increased with depth, ranging from 0.4×10 4 to 3.3×10 4 cells·mL -1. Ratios of EUB probe binding cells to DAPI counts ranged from 52.3 to 74.1% in free-living bacteria and from 39.6 to 66.7% in aggregated bacteria, respectively. Community composition of aggregated bacteria was very different from free-living bacteria, especially at 25m depth where highest phytoplankton numbers were observed. The vertical profile of aggregated bacteria community was very characteristic. Beta-Proteobacteria increased with depth down to 100m. At 250m, gamma-Proteobacteria was 44% of DAPI bound cells, while other groups were less than 1%. We conclude that community structures of free-living and aggregated bacteria were different, and they may sustain the ecosystem in independent ways. 展开更多
关键词 Bacterial aggregates Community structure FISH Lake Baikal
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Multivariate Aggregated NOMA for Resource Aware Wireless Network Communication Security
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作者 V.Sridhar K.V.Ranga Rao +4 位作者 Saddam Hussain Syed Sajid Ullah Roobaea Alroobaea Maha Abdelhaq Raed Alsaqour 《Computers, Materials & Continua》 SCIE EI 2023年第1期1693-1708,共16页
NonorthogonalMultiple Access(NOMA)is incorporated into the wireless network systems to achieve better connectivity,spectral and energy effectiveness,higher data transfer rate,and also obtain the high quality of servic... NonorthogonalMultiple Access(NOMA)is incorporated into the wireless network systems to achieve better connectivity,spectral and energy effectiveness,higher data transfer rate,and also obtain the high quality of services(QoS).In order to improve throughput and minimum latency,aMultivariate Renkonen Regressive Weighted Preference Bootstrap Aggregation based Nonorthogonal Multiple Access(MRRWPBA-NOMA)technique is introduced for network communication.In the downlink transmission,each mobile device’s resources and their characteristics like energy,bandwidth,and trust are measured.Followed by,the Weighted Preference Bootstrap Aggregation is applied to recognize the resource-efficient mobile devices for aware data transmission by constructing the different weak hypotheses i.e.,Multivariate Renkonen Regression functions.Based on the classification,resource and trust-aware devices are selected for transmission.Simulation of the proposed MRRWPBA-NOMA technique and existing methods are carried out with different metrics such as data delivery ratio,throughput,latency,packet loss rate,and energy efficiency,signaling overhead.The simulation results assessment indicates that the proposed MRRWPBA-NOMA outperforms well than the conventional methods. 展开更多
关键词 Mobile network multivariate renkonen regression weighted preference bootstrap aggregation resource-aware secure data communication NOMA
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Component Carrier Selection and Beamforming on Carrier Aggregated Channels in Heterogeneous Networks
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作者 Changyin Sun Hongfeng Qing +1 位作者 Shaopeng Wang Guangyue Lu 《Communications and Network》 2013年第3期211-216,共6页
In this paper, component carrier selection and beamforming on carrier aggregated channels in Heterogeneous Networks are proposed. The scheme jointly selects the component carrier and precoding (i.e. beamforming) vecto... In this paper, component carrier selection and beamforming on carrier aggregated channels in Heterogeneous Networks are proposed. The scheme jointly selects the component carrier and precoding (i.e. beamforming) vectors with the cooperation of the other cells to deal with the interference between Macro cell and Pico cell. The component carrier selection and beamforming is achieved by optimizing the multi-cell downlink throughput. This optimization results in shutting down a subset of the component carrier in order to allow for a perfect interference removal at the receive side in the dense low power node deployment scenario. Additionally, algorithm based on Branch and Bound Method is used to reduce the search complexity of the algorithm. Simulation results show that the proposed scheme can achieve high cell-average and cell-edge throughput for the Pico cell in the Heterogeneous Networks. 展开更多
关键词 Heterogeneous Network Inter-cell Interference COORDINATION BEAMFORMING CARRIER AGGREGATION
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Effects of Conservation Tillage on Total and Aggregated Soil Organic Carbon in the Andes
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作者 Marcela Quintero Nicholas B. Comerford 《Open Journal of Soil Science》 2013年第8期361-373,共13页
Many Andisols of the Andes have been disturbed by traditional potato-based rotation agriculture disrupting soil structure, water retention capacity and organic matter content. This study was undertaken to investigate ... Many Andisols of the Andes have been disturbed by traditional potato-based rotation agriculture disrupting soil structure, water retention capacity and organic matter content. This study was undertaken to investigate the contribution of conservation farming technology or reduced tillage in potato-based rotations in the Colombian Andes in order to rehabilitate total and aggregated soil organic C in disturbed organic matter-rich Andisols. Soils were sampled from farms with 7-year of reduced tillage and farms with conventional farming practices. Ultrasound energy was applied to samples to disrupt aggregation and total soil C was determined in order to investigate the amount of carbon held inside the aggregates of different soil size classes. Results indicated that reduced tillage in potato-based crop rotations increased the soil C concentration and average C content in the whole profile (≈117 cm depth) by 50 and 33% (1636 t C ha?1 vs. 1224 t C ha?1), respectively, as compared to conventional farming practices. Carbon content increased 177% in the subsoil (A2 horizon, 78 -117 cm depth, from 215 to 596 t?ha?1), although most of the soil C was in the A1 horizon (between 0 -78 cm average thickness, 1097 t?ha?1). These increases show that reduced tillage enhances C stores in Andisols which are already high in organic matter. In addition, C in aggregates represented more than 80% of the total organic matter and it was positively affected by conservation practices. The C increase was preferential in the smaller macroaggregates ( 展开更多
关键词 Conservation TILLAGE SOIL Organic Carbon SOIL AGGREGATES ANDES POTATO
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Mixed Contiguous and Aggregated Spectrum Allocation Algorithm for CR based TD-LTE System
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作者 Xiaoyan Liu Qingyi Quan +2 位作者 Peng Lei Wenbin Guo Wenbo Wang 《Communications and Network》 2013年第3期298-302,共5页
Cognitive Radio (CR) is a promising technology to increase the efficiency of spectrum by opportunistic access. However, in many cases the sensed spectrum is so broken that it cannot be utilized sufficiently with tradi... Cognitive Radio (CR) is a promising technology to increase the efficiency of spectrum by opportunistic access. However, in many cases the sensed spectrum is so broken that it cannot be utilized sufficiently with traditional continuous spectrum allocation strategy. Spectrum aggregation can make full use of narrow spectrum fragments while the overhead it brings may reduce the overall performance of the system. This paper proposes a Mixed Contiguous and Aggregated Spectrum Allocation (MixCASA) algorithm for CR based TD-LTE Networks. This algorithm combines contiguous with discontiguous spectrum allocation together in order to guarantee the feasibility and efficiency of system. Simulation results show that the MixCASA algorithm can increase the number of allocated channels, and reduce the overhead brought by excessive spectrum aggregation as well. 展开更多
关键词 COGNITIVE RADIO TD-LTE SPECTRUM ALLOCATION SPECTRUM AGGREGATION
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Control over the aggregated structure of donor–acceptor conjugated polymerfilms for high-mobility organicfield-effect transistors 被引量:2
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作者 Xinxiu Cao Yanchun Han 《Aggregate》 EI CAS 2024年第3期26-49,共24页
Donor–acceptor(D-A)conjugated polymers have demonstrated great potential in organicfield-effect transistors application,and their aggregated structure is a crucial factor for high charge mobility.However,the aggregat... Donor–acceptor(D-A)conjugated polymers have demonstrated great potential in organicfield-effect transistors application,and their aggregated structure is a crucial factor for high charge mobility.However,the aggregated structure of D-A conjugated polymerfilms is complex and the structure–property relationship is difficult to understand.This review provides an overview of recent progress in controlling the aggregated structure of D-A conjugated polymerfilms for higher mobility,including the mechanisms,methods,and properties.Wefirst discuss the multilevel microstructures of D-A conjugated polymerfilms,and then summarize the current understanding of the relationship betweenfilm microstructures and charge transport properties.Subsequently,we review the theory of D-A conjugated polymer crystallization.After that,we summarize the common methods to control the aggregated structure of semi-crystalline and near-amorphous D-A conjugated polymerfilms,such as crystallites and aggregates,tie chains,film alignment,and attempt to understand them from the basic theory of polymer crystallization.Finally,we provide the current challenges in controlling the aggregated structure of D-A conjugated polymerfilms and in understanding the structure–property relationship. 展开更多
关键词 aggregated structure charge mobility CRYSTALLIZATION D-A conjugated polymers near-amorphous organicfield-effect transistors
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Small heat shock protein B8:from cell functions to its involvement in diseases and potential therapeutic applications 被引量:1
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作者 Marta Chierichetti Riccardo Cristofani +12 位作者 Valeria Crippa Veronica Ferrari Marta Cozzi Elena Casarotto Paola Pramaggiore Laura Cornaggia Guglielmo Patelli Ali Mohamed Margherita Piccolella Mariarita Galbiati Paola Rusmini Barbara Tedesco Angelo Poletti 《Neural Regeneration Research》 SCIE CAS 2025年第10期2872-2886,共15页
Heat shock protein family B(small)member 8(HSPB8)is a 22 kDa ubiquitously expressed protein belonging to the family of small heat shock proteins.HSPB8 is involved in various cellular mechanisms mainly related to prote... Heat shock protein family B(small)member 8(HSPB8)is a 22 kDa ubiquitously expressed protein belonging to the family of small heat shock proteins.HSPB8 is involved in various cellular mechanisms mainly related to proteotoxic stress response and in other processes such as inflammation,cell division,and migration.HSPB8 binds misfolded clients to prevent their aggregation by assisting protein refolding or degradation through chaperone-assisted selective autophagy.In line with this function,the pro-degradative activity of HSPB8 has been found protective in several neurodegenerative and neuromuscular diseases characterized by protein misfolding and aggregation.In cancer,HSPB8 has a dual role being capable of exerting either a pro-or an anti-tumoral activity depending on the pathways and factors expressed by the model of cancer under investigation.Moreover,HSPB8 exerts a protective function in different diseases by modulating the inflammatory response,which characterizes not only neurodegenerative diseases,but also other chronic or acute conditions affecting the nervous system,such as multiple sclerosis and intracerebellar hemorrhage.Of note,HSPB8 modulation may represent a therapeutic approach in other neurological conditions that develop as a secondary consequence of other diseases.This is the case of cognitive impairment related to diabetes mellitus,in which HSPB8 exerts a protective activity by assuring mitochondrial homeostasis.This review aims to summarize the diverse and multiple functions of HSPB8 in different pathological conditions,focusing on the beneficial effects of its modulation.Drug-based and alternative therapeutic approaches targeting HSPB8 and its regulated pathways will be discussed,emphasizing how new strategies for cell and tissue-specific delivery represent an avenue to advance in disease treatments. 展开更多
关键词 AGGREGATION AUTOPHAGY cancer CHAPERONE chaperone-assisted selective autophagy cognitive impairment HSPB8 NEUROINFLAMMATION neuromuscular diseases therapy
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AN EXTENDED AGGREGATED RATIO ANALYSIS IN DEA 被引量:5
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作者 Malin SONG Jie WU Yumei WANG 《Journal of Systems Science and Systems Engineering》 SCIE EI CSCD 2011年第2期249-256,共8页
Data Envelopment Analysis(DEA) and Ratio Analysis(RA) are two widely used methods for measuring units' productivity and any other criteria that could be assessed based on the available input and output variables.... Data Envelopment Analysis(DEA) and Ratio Analysis(RA) are two widely used methods for measuring units' productivity and any other criteria that could be assessed based on the available input and output variables.A number of researchers have studied DEA and RA and noted the positive and negative differences between them.Aggregated ratio analysis(ARA) model,which provide an important linkage between DEA and RA theory,is equivalent to the CCR DEA model,and this equivalence property offers a great deal of opportunities for DEA to be interpreted and applied in different ways.This paper extends the results of ARA model and proposes an extended aggregated ratio analysis(EARA) model,similar as the development from CCR model to BCC model in DEA context.The proposed model can offer an insight into the characteristic of returns to scale,playing the corresponding role as BCC model does.The numerical example is revisited in the paper and the results are compared. 展开更多
关键词 Data Envelopment Analysis(DEA) aggregated ratio analysis efficiency evaluation returns to scale
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Optimized Dispatching Method for Flexibility Improvement of AC-MTDC Distribution Systems Considering Aggregated Electric Vehicles 被引量:2
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作者 Xingyue Jiang Shouxiang Wang +1 位作者 Qianyu Zhao Xuan Wang 《Journal of Modern Power Systems and Clean Energy》 SCIE EI CSCD 2023年第6期1857-1867,共11页
With the increasing use of renewable resources and electric vehicles(EVs), the variability and uncertainty in their nature put forward a high requirement for flexibility in AC distribution system incorporating voltage... With the increasing use of renewable resources and electric vehicles(EVs), the variability and uncertainty in their nature put forward a high requirement for flexibility in AC distribution system incorporating voltage source converter(VSC) based multi-terminal direct current(MTDC) grids. In order to improve the capability of distribution systems to cope with uncertainty, the flexibility enhancement of AC-MTDC distribution systems considering aggregated EVs is studied. Firstly, the charging and discharging model of one EV is proposed considering the users' demand difference and traveling needs. Based on this, a vehicle-to-grid(V2G) control strategy for aggregated EVs to participate in the flexibility promotion of distribution systems is provided. After that, an optimal flexible dispatching method is proposed to improve the flexibility of power systems through cooperation of VSCs, controllable distributed generations(CDGs), aggregated EVs, and energy storage systems(ESSs). Finally, a case study of an AC-MTDC distribution system is carried out. Simulation results show that the proposed dispatching method is capable of effectively enhancing the system flexibility, reducing renewable power curtailment, decreasing load abandonment, and cutting down system cost. 展开更多
关键词 Multi-terminal direct current(MTDC) distribution system aggregated electric vehicle(EV) FLEXIBILITY optimized dispatching
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