A two-stage damage detection approach is proposed and experimentally demonstrated on a complicated spatial model structure with a limited number of measurements. In the experiment,five known damage patterns,including ...A two-stage damage detection approach is proposed and experimentally demonstrated on a complicated spatial model structure with a limited number of measurements. In the experiment,five known damage patterns,including 3 brace damage cases and 2 joint damage cases,were simulated by removing braces and weakening beam鈥揷olumn connections in the structure. The limited acceleration response data generated by hammer impact were used for system identification,and modal parameters were extracted by using the eigensystem realization algorithm. In the first stage,the possible damaged locations are determined by using the damage index and the characteristics of the analytical model itself,and the extent of damage for those substructures identified at stage I is estimated in the second stage by using a second-order eigen-sensitivity approximation method. The main contribution of this paper is to test the two-stage method by using the real dynamic data of a complicated spatial model structure with limited sensors. The analysis results indicate that the two-stage approach is ableto detect the location of both damage cases,only the severity of brace damage cases can be assessed,and the reasonable analytical model is critical for successful damage detection.展开更多
Seventy-eight cases of retinoblastoma (Rb) diagnosed at the Eye ENT Hospital, Shanghai Medical University from 1953 to 1985 were studied. The results of multiple logistic regression analysis and conditional probabilit...Seventy-eight cases of retinoblastoma (Rb) diagnosed at the Eye ENT Hospital, Shanghai Medical University from 1953 to 1985 were studied. The results of multiple logistic regression analysis and conditional probability model showed that high fetal order had a moderate risk (OR=1.28, P<0.05) of developing unilateral Rb. Both unilateral and bilateral cases were independent of parental ages, and no interaction could be found between fetal order and paternal of maternal age; also, the effect of fetal order was not confounded by parental ages.展开更多
The article represents the glaucoma disability rates in Ukraine and touches upon medical and social aspects of the problem We have screened a data from source medical documents and analyzed the MSEK （Physical Disabil...The article represents the glaucoma disability rates in Ukraine and touches upon medical and social aspects of the problem We have screened a data from source medical documents and analyzed the MSEK （Physical Disability Board of Review） statistical reporting data, further used as a basis for calculation of live indices of general and primary disabilities caused by eye diseases, including the ones caused by primary open-angle glaucoma （7.05% and 9.99%, respectively）, the extensive distribution indices of disability by gender （75.74% male）, age （59.29% of II maturity patients）, and a disability group （56% of patients recognized disabled persons of groups I and II）. Our findings indicate a lack of modern science-based approaches to diagnosis, rehabilitation, and socio-medical examination of patients with ophthalmologic pathologies, thus requiring deeper study of this problem.展开更多
Extracting the neutral hydrogen （HI） signal is a great challenge for cosmological 21 cm experiments; both the astrophysical foregrounds and receiver noise are typically several orders of magnitude greater than the 2...Extracting the neutral hydrogen （HI） signal is a great challenge for cosmological 21 cm experiments; both the astrophysical foregrounds and receiver noise are typically several orders of magnitude greater than the 21 cm signal. However, the different properties of the 21 cm signal, foreground and noise can be exploited to separate these components. The foregrounds are generally smooth or correlated over the frequency space along a line of sight （LOS）, while both the 21 cm signal and noise vary stochastically along the same LoS. The foreground can be removed by filtering out the smooth component in frequency space. The receiver noise is basically uncorrelated for observations at different times, hence for surveys it is also uncorrelated in different directions, while the 21 cm signal, which traces the large scale structure, is correlated up to certain scales. In this exercise, we apply Wiener filters in frequency and angular space to extract the 21 cm signals. We found that the method works well. Inaccurate knowl- edge about the beam could degrade the reconstruction, but the overall result is still good, showing that the method is fairly robust.展开更多
Background Food-borne trematodiases(FBTs),mainly encompassing clonorchiasis,fascioliasis,fasciolopsiasis,opisthorchiasis,and paragonimiasis,is a neglected public health problem,particularly in the WHO South-East Asia ...Background Food-borne trematodiases(FBTs),mainly encompassing clonorchiasis,fascioliasis,fasciolopsiasis,opisthorchiasis,and paragonimiasis,is a neglected public health problem,particularly in the WHO South-East Asia and the Western Pacific regions.This study evaluates the global,regional,and national disease burden of FBTs from 1990 to 2021 and projects trends to 2030,underscore the need for targeted prevention and control.Methods Using the Global Burden of Disease 2021 database,the crude and the age-standardized prevalence rate(ASPR)and age-standardized prevalence disability-adjusted life years rate(ASDR)of FBTs at the global,regional and national level from 1990 to 2021 were described.The pivotal years of trend changes were identified using joinpoint regression analysis.The effects of age,period,cohort on FBTs prevalence and correlation with the sociode-mographic index(SDI)was analyzed.Finally,the worldwide disability-adjusted life years(DALYs)for FBTs,projected up to 2030 using the Bayesian age-period-cohort model,were analyzed.Results In 2021,44,466,329 FBTs cases[95%uncertainty interval(UI):40,017,217,50,034,921],and 998,028 DALYs[95%UI:569,766,1,638,112]were estimated across 17 countries.The Western Pacific region exhibited the highest ASPR and ASDR,with the values of 1649.26(95%UI:1461.95,1881.64)and 36.54(95%UI:19.77,64.16),respectively.From 1990 to 2021,Lao PDR,Thailand,and the Philippines showed the most substantial declines in FBTs,while Kazakhstan had the largest average annual percentage change in DALYs(-6.60,95%UI:-7.10,-6.10).High-middle and middle SDI countries exhibited higher burden,with ASDR values of 28.03(95%UI:15.41,48.73)and 16.63(95%UI:9.32,27.68),respectively.The disease burden was greater among males,peaking in the 50-59 age group.The projected ASDR in 2030 is 13.10 for males and 8.40 for females.Conclusions FBTs remain a public health threat,with the global ASDR projected to remain stable,showing only a slight decrease by 2030.Low-income countries face ambiguous mortality rates and underestimated disease burdens,highlighting the need for improved surveillance.To achieve the 2030 NTD goal,comprehensive surveillance and integrated strategies derived using a One Health approach should be prioritized to control FBTs effectively.展开更多
基金supported by the National Natural Science Foundation of China (90815025, 90715032 and 50808013)
文摘A two-stage damage detection approach is proposed and experimentally demonstrated on a complicated spatial model structure with a limited number of measurements. In the experiment,five known damage patterns,including 3 brace damage cases and 2 joint damage cases,were simulated by removing braces and weakening beam鈥揷olumn connections in the structure. The limited acceleration response data generated by hammer impact were used for system identification,and modal parameters were extracted by using the eigensystem realization algorithm. In the first stage,the possible damaged locations are determined by using the damage index and the characteristics of the analytical model itself,and the extent of damage for those substructures identified at stage I is estimated in the second stage by using a second-order eigen-sensitivity approximation method. The main contribution of this paper is to test the two-stage method by using the real dynamic data of a complicated spatial model structure with limited sensors. The analysis results indicate that the two-stage approach is ableto detect the location of both damage cases,only the severity of brace damage cases can be assessed,and the reasonable analytical model is critical for successful damage detection.
文摘Seventy-eight cases of retinoblastoma (Rb) diagnosed at the Eye ENT Hospital, Shanghai Medical University from 1953 to 1985 were studied. The results of multiple logistic regression analysis and conditional probability model showed that high fetal order had a moderate risk (OR=1.28, P<0.05) of developing unilateral Rb. Both unilateral and bilateral cases were independent of parental ages, and no interaction could be found between fetal order and paternal of maternal age; also, the effect of fetal order was not confounded by parental ages.
文摘The article represents the glaucoma disability rates in Ukraine and touches upon medical and social aspects of the problem We have screened a data from source medical documents and analyzed the MSEK （Physical Disability Board of Review） statistical reporting data, further used as a basis for calculation of live indices of general and primary disabilities caused by eye diseases, including the ones caused by primary open-angle glaucoma （7.05% and 9.99%, respectively）, the extensive distribution indices of disability by gender （75.74% male）, age （59.29% of II maturity patients）, and a disability group （56% of patients recognized disabled persons of groups I and II）. Our findings indicate a lack of modern science-based approaches to diagnosis, rehabilitation, and socio-medical examination of patients with ophthalmologic pathologies, thus requiring deeper study of this problem.
基金supported by the Ministry of Science and Technology(2016YFE0100300)the National Natural Science Foundation of China(Grant Nos.11473044,U1501501,U1631118 and 11633004)+1 种基金the Chinese Academy of Sciences(QYZDJ-SSW-SLH017)support by the CSC Cai Yuanpei grant
文摘Extracting the neutral hydrogen （HI） signal is a great challenge for cosmological 21 cm experiments; both the astrophysical foregrounds and receiver noise are typically several orders of magnitude greater than the 21 cm signal. However, the different properties of the 21 cm signal, foreground and noise can be exploited to separate these components. The foregrounds are generally smooth or correlated over the frequency space along a line of sight （LOS）, while both the 21 cm signal and noise vary stochastically along the same LoS. The foreground can be removed by filtering out the smooth component in frequency space. The receiver noise is basically uncorrelated for observations at different times, hence for surveys it is also uncorrelated in different directions, while the 21 cm signal, which traces the large scale structure, is correlated up to certain scales. In this exercise, we apply Wiener filters in frequency and angular space to extract the 21 cm signals. We found that the method works well. Inaccurate knowl- edge about the beam could degrade the reconstruction, but the overall result is still good, showing that the method is fairly robust.
基金supported by Jiangsu Science and Technology Department(K20221061)the Guizhou Provincial Scientifc and Technological Program(Qian Ke He(2023)General 183).
文摘Background Food-borne trematodiases(FBTs),mainly encompassing clonorchiasis,fascioliasis,fasciolopsiasis,opisthorchiasis,and paragonimiasis,is a neglected public health problem,particularly in the WHO South-East Asia and the Western Pacific regions.This study evaluates the global,regional,and national disease burden of FBTs from 1990 to 2021 and projects trends to 2030,underscore the need for targeted prevention and control.Methods Using the Global Burden of Disease 2021 database,the crude and the age-standardized prevalence rate(ASPR)and age-standardized prevalence disability-adjusted life years rate(ASDR)of FBTs at the global,regional and national level from 1990 to 2021 were described.The pivotal years of trend changes were identified using joinpoint regression analysis.The effects of age,period,cohort on FBTs prevalence and correlation with the sociode-mographic index(SDI)was analyzed.Finally,the worldwide disability-adjusted life years(DALYs)for FBTs,projected up to 2030 using the Bayesian age-period-cohort model,were analyzed.Results In 2021,44,466,329 FBTs cases[95%uncertainty interval(UI):40,017,217,50,034,921],and 998,028 DALYs[95%UI:569,766,1,638,112]were estimated across 17 countries.The Western Pacific region exhibited the highest ASPR and ASDR,with the values of 1649.26(95%UI:1461.95,1881.64)and 36.54(95%UI:19.77,64.16),respectively.From 1990 to 2021,Lao PDR,Thailand,and the Philippines showed the most substantial declines in FBTs,while Kazakhstan had the largest average annual percentage change in DALYs(-6.60,95%UI:-7.10,-6.10).High-middle and middle SDI countries exhibited higher burden,with ASDR values of 28.03(95%UI:15.41,48.73)and 16.63(95%UI:9.32,27.68),respectively.The disease burden was greater among males,peaking in the 50-59 age group.The projected ASDR in 2030 is 13.10 for males and 8.40 for females.Conclusions FBTs remain a public health threat,with the global ASDR projected to remain stable,showing only a slight decrease by 2030.Low-income countries face ambiguous mortality rates and underestimated disease burdens,highlighting the need for improved surveillance.To achieve the 2030 NTD goal,comprehensive surveillance and integrated strategies derived using a One Health approach should be prioritized to control FBTs effectively.
