Recent advancements in radiotherapy for esophageal cancer have significantly improved treatment outcomes and patient quality of life.Traditional radiotherapy techniques have been enhanced by the integration of advance...Recent advancements in radiotherapy for esophageal cancer have significantly improved treatment outcomes and patient quality of life.Traditional radiotherapy techniques have been enhanced by the integration of advanced imaging and precision targeting technologies,such as intensity-modulated radiotherapy and proton therapy,which allow for more accurate tumor targeting while minimizing damage to surrounding healthy tissues.Additionally,combining radiotherapy with immunotherapy has shown promising results,leveraging the body’s im-mune response to enhance the effectiveness of cancer treatment.Studies have also highlighted the benefits of neoadjuvant chemoradiation followed by surgical resection,which has been associated with improved overall survival rates com-pared to radiotherapy alone.These innovations are paving the way for more effe-ctive and personalized treatment strategies,offering new hope for patients with esophageal cancer.展开更多
The intricate hierarchical structure of musculoskeletal tissues,including bone and interface tissues,necessitates the use of complex scaffold designs and material structures to serve as tissue-engineered substitutes.T...The intricate hierarchical structure of musculoskeletal tissues,including bone and interface tissues,necessitates the use of complex scaffold designs and material structures to serve as tissue-engineered substitutes.This has led to growing interest in the development of gradient bone scaffolds with hierarchical structures mimicking the extracellular matrix of native tissues to achieve improved therapeutic outcomes.Building on the anatomical characteristics of bone and interfacial tissues,this review provides a summary of current strategies used to design and fabricate biomimetic gradient scaffolds for repairing musculoskeletal tissues,specifically focusing on methods used to construct compositional and structural gradients within the scaffolds.The latest applications of gradient scaffolds for the regeneration of bone,osteochondral,and tendon-to-bone interfaces are presented.Furthermore,the current progress of testing gradient scaffolds in physiologically relevant animal models of skeletal repair is discussed,as well as the challenges and prospects of moving these scaffolds into clinical application for treating musculoskeletal injuries.展开更多
《宇航学报》英文版(Advances in Astronautics)由中国宇航学会与哈尔滨工业大学联合主办,与中国宇航学会主办的中文旗舰学术期刊《宇航学报》实施一体化建设,定位于覆盖宇航领域主要技术方向的综合性英文学术期刊。本刊为英文季刊,与...《宇航学报》英文版(Advances in Astronautics)由中国宇航学会与哈尔滨工业大学联合主办,与中国宇航学会主办的中文旗舰学术期刊《宇航学报》实施一体化建设,定位于覆盖宇航领域主要技术方向的综合性英文学术期刊。本刊为英文季刊,与施普林格·自然集团合作出版,并已被Ei Compendex、Scopus等权威数据库收录,为全球科研人员提供高质量的成果发表平台。展开更多
《宇航学报》英文版(Advances in Astronautics)由中国宇航学会与哈尔滨工业大学联合主办,与中国宇航学会主办的中文旗舰学术期刊《宇航学报》实施一体化建设,定位于覆盖宇航领域主要技术方向的综合性英文学术期刊。本刊为英文季刊,与...《宇航学报》英文版(Advances in Astronautics)由中国宇航学会与哈尔滨工业大学联合主办,与中国宇航学会主办的中文旗舰学术期刊《宇航学报》实施一体化建设,定位于覆盖宇航领域主要技术方向的综合性英文学术期刊。本刊为英文季刊,与施普林格·自然集团合作出版,并已被Ei Compendex、Scopus等权威数据库收录,为全球科研人员提供高质量的成果发表平台。展开更多
《宇航学报》英文版(Advances in Astronautics)由中国宇航学会与哈尔滨工业大学联合主办,与中国宇航学会主办的中文旗舰学术期刊《宇航学报》实施一体化建设,定位于覆盖宇航领域主要技术方向的综合性英文学术期刊。本刊为英文季刊,与...《宇航学报》英文版(Advances in Astronautics)由中国宇航学会与哈尔滨工业大学联合主办,与中国宇航学会主办的中文旗舰学术期刊《宇航学报》实施一体化建设,定位于覆盖宇航领域主要技术方向的综合性英文学术期刊。本刊为英文季刊,与施普林格·自然集团合作出版,并已被Ei Compendex、Scopus等权威数据库收录,为全球科研人员提供高质量的成果发表平台。展开更多
《宇航学报》英文版(Advances in Astronautics)由中国宇航学会与哈尔滨工业大学联合主办,与中国宇航学会主办的中文旗舰学术期刊《宇航学报》实施一体化建设,定位于覆盖宇航领域主要技术方向的综合性英文学术期刊。本刊为英文季刊,与...《宇航学报》英文版(Advances in Astronautics)由中国宇航学会与哈尔滨工业大学联合主办,与中国宇航学会主办的中文旗舰学术期刊《宇航学报》实施一体化建设,定位于覆盖宇航领域主要技术方向的综合性英文学术期刊。本刊为英文季刊,与施普林格·自然集团合作出版,并已被Ei Compendex、Scopus等权威数据库收录,为全球科研人员提供高质量的成果发表平台。展开更多
《宇航学报》英文版(Advances in Astronautics)由中国宇航学会与哈尔滨工业大学联合主办,与中国宇航学会主办的中文旗舰学术期刊《宇航学报》实施一体化建设,定位于覆盖宇航领域主要技术方向的综合性英文学术期刊。本刊为英文季刊,与...《宇航学报》英文版(Advances in Astronautics)由中国宇航学会与哈尔滨工业大学联合主办,与中国宇航学会主办的中文旗舰学术期刊《宇航学报》实施一体化建设,定位于覆盖宇航领域主要技术方向的综合性英文学术期刊。本刊为英文季刊,与施普林格·自然集团合作出版,并已被Ei Compendex、Scopus等权威数据库收录,为全球科研人员提供高质量的成果发表平台。展开更多
In recent years,gratitude intervention,as an application method of positive psychology,has gradually attracted the attention of researchers.Gratitude intervention is considered to be an effective psychological interve...In recent years,gratitude intervention,as an application method of positive psychology,has gradually attracted the attention of researchers.Gratitude intervention is considered to be an effective psychological intervention,especially in patients with malignant tumors.This study reviews the research progress of gratitude intervention in patients with malignant tumors,focusing on the mechanism,implementation methods,effect evaluation and challenges in clinical application of gratitude intervention,in the hope of providing a theoretical support and practical guideline for future research and practice.展开更多
Chromones serve as versatile heterocyclic scaffolds and are common core structural units in a variety of natural products and bioactive organic molecules.This area of research,at the forefront of organic synthesis,has...Chromones serve as versatile heterocyclic scaffolds and are common core structural units in a variety of natural products and bioactive organic molecules.This area of research,at the forefront of organic synthesis,has seen remarkable progress in recent years.Among the various synthetic methodologies for accessing chromone scaffolds,the tandem annulation of o-hydroxyaryl enaminones has emerged as a robust and practical strategy.This approach,through direct vinyl C-H bond functionalization of o-hydroxyaryl enaminones,enables the construction of structurally diverse chromones(including 3-substituted chromones,2-substituted chromones,and 2,3-disubstituted chromones)and their derivatives since mid-2019.In this review,we highlight recent advances in the synthesis of various types of chromones and their derivatives,achieved through tandem direct vinyl C-H activation and chromone annulation of o-hydroxyaryl enaminones.展开更多
This special issue of the Asian Journal of Andrology is fully dedicated to the thematic area of non-obstructive azoospermia(NOA),one of the most complex and challenging conditions in the realm of andrology,urology,and...This special issue of the Asian Journal of Andrology is fully dedicated to the thematic area of non-obstructive azoospermia(NOA),one of the most complex and challenging conditions in the realm of andrology,urology,and reproductive medicine.展开更多
The convergence of materials science and biotechnology has catalyzed the development of innovative platforms,including nanotechnology,smart sensors,and supramolecular materials,significantly advancing the progress in ...The convergence of materials science and biotechnology has catalyzed the development of innovative platforms,including nanotechnology,smart sensors,and supramolecular materials,significantly advancing the progress in the field of life sciences[1−7].Among them,supramolecular materials have garnered increasing attention in life sciences owing to their distinctive self-assembly capabilities and intelligent responsiveness[8−12].展开更多
Background:Non-valvular atrial fibrillation(NVAF),the most prevalent cardiac arrhythmia globally,poses a dual challenge of thromboembolic and bleeding risks,with stroke being the most devastating complication.Despite ...Background:Non-valvular atrial fibrillation(NVAF),the most prevalent cardiac arrhythmia globally,poses a dual challenge of thromboembolic and bleeding risks,with stroke being the most devastating complication.Despite advancements in anticoagulation and rhythm control,patient outcomes remain suboptimal.Aim:This review synthesizes current evidence on the pathophysiological mechanisms,multidimensional management strategies,and emerging innovations in NVAF to inform clinical practice and future research directions.Methods:A systematic literature search was conducted across nine databases(CNKI,Wanfang,SinoMed,VIP,PubMed,Web of Science,Cochrane Library,Embase,and MEDLINE)using combined Medical Subject Headings(MeSH)and free-text terms,including“atrial fibrillation,”“non-valvular atrial fibrillation,”“risk factors,”and“mechanism”(and their Chinese equivalents).Studies on NVAF pathogenesis,therapeutic interventions,and risk stratification tools were analyzed.Results:(1)Risk Factors and Pathophysiology:NVAF progression is driven by hemodynamic stress(e.g.,hypertension),metabolic disorders(e.g.,obesity,diabetes),chronic inflammation,and fibrosis.Biomarkers such as CRP and Galectin-3,along with TGF-β/Smad signaling,are central to atrial remodeling.(2)Anticoagulation Controversies:While NOACs reduce stroke risk compared to warfarin(HR=0.79),challenges persist in extreme body weight populations and drug-drug interactions(e.g.,with P-glycoprotein inhibitors).(3)Left Atrial Appendage Closure(LAAC):LAAC demonstrates non-inferiority to anticoagulation in stroke prevention(HR=0.79)with reduced major bleeding(HR=0.49),though device-related thrombosis(1.8–7%)remains a concern.(4)Precision Medicine:AI-driven models enhance stroke prediction(AUC=0.71;sensitivity 92%),while genotype-guided warfarin dosing shortens INR stabilization by 40%.(5)Lifestyle Interventions:Combined Mediterranean diet and moderate exercise reduce AF burden(HR=0.69)and reverse left atrial enlargement(LAVI reduced by 12%).(6)Multidisciplinary Care:Integrated“heart-brain team”approaches combining LAAC and PFO closure lower annual stroke recurrence from 8.2%to 2.1%,while comprehensive rehabilitation improves functional capacity(6MWD+45 m)and quality of life(SF-36+12 points).Conclusion:NVAF management has evolved from isolated anticoagulation to a multidimensional paradigm integrating genomics,AI,and lifestyle modification.Future priorities include validating long-term outcomes of novel therapies,addressing evidence gaps in special populations,and implementing digitally enabled,cross-disciplinary care models to mitigate the global burden of NVAF-related complications.展开更多
On March 27,the National Natural Science Foundation of China(NSFC)released the annual“Top 10 Science Advances of China”for the year 2024.Topping the list was a research that revealed volcanic activities occurring ab...On March 27,the National Natural Science Foundation of China(NSFC)released the annual“Top 10 Science Advances of China”for the year 2024.Topping the list was a research that revealed volcanic activities occurring about 2.8 billion years ago on the far side of the Moon,based on samples returned by the Chang’e-6(CE-6)mission,the first successful effort to bring back samples from the lunar farside.展开更多
Hyaline Membrane Disease(HMD)in newborns,also known as neonatal respiratory distress syndrome,is a common critical illness in premature infants,with an incidence inversely correlated with gestational age,posing a seri...Hyaline Membrane Disease(HMD)in newborns,also known as neonatal respiratory distress syndrome,is a common critical illness in premature infants,with an incidence inversely correlated with gestational age,posing a serious threat to the life and health of newborns.This paper systematically reviews the core pathogenesis of HMD,focusing on the abnormal metabolism of pulmonary surfactant(PS),genetic factors,immature lung development,and the synergistic effects of inflammatory oxidative stress.It highlights the advances in non-invasive ventilation(NIV)therapy for HMD,including the mechanisms of action,clinical application effects,and optimization strategies of mainstream modalities such as nasal continuous positive airway pressure ventilation(NCPAP),nasal intermittent positive pressure ventilation(NIPPV),and heated humidified high-flow nasal cannula ventilation(HHHFNC).The aim is to provide references for standardized clinical treatment.展开更多
Dairy wastewater,a kind of high concentration organic wastewater,is produced in large quantities and difficult to treat,and has a negative impact on the ecological environment.In this study,the source,composition,wate...Dairy wastewater,a kind of high concentration organic wastewater,is produced in large quantities and difficult to treat,and has a negative impact on the ecological environment.In this study,the source,composition,water quality characteristics of dairy wastewater and its impact on the ecological environment were analyzed,and the treatment methods of dairy wastewater at home and abroad in recent years were summarized,in order to provide a reference for the treatment of dairy wastewater.展开更多
Allogeneic hematopoietic cell transplantation(allo-HCT) remains a cornerstone therapy for severe hematologic malignancies, offering a potential cure when conventional therapies are ineffective. However, not all patien...Allogeneic hematopoietic cell transplantation(allo-HCT) remains a cornerstone therapy for severe hematologic malignancies, offering a potential cure when conventional therapies are ineffective. However, not all patients are suitable recipients of allo-HCT, particularly the elderly patients and those with high comorbidity burdens.Furthermore, patients who develop relapse or graft failure after initial transplantation encounter additional challenges when evaluated for a second transplant.展开更多
Benign esophageal stricture is characterized by the narrowing of the digestivetract lumen due to multiple factors. Endoscopic treatment is the first treatmentchoice and includes endoscopic dilatation, drug injection, ...Benign esophageal stricture is characterized by the narrowing of the digestivetract lumen due to multiple factors. Endoscopic treatment is the first treatmentchoice and includes endoscopic dilatation, drug injection, stenosis incision, stentimplantation, stem cell flap transplantation, etc. However, there are currently nospecific clinical standards or guidelines to quantify a series of specific parametersin the treatment of benign esophageal stricture, such as the frequency of drugadministration, dosage, dilation inner diameter, and number of treatments. Thisleads to operator bias in clinical practice and inconsistent treatment outcomesamong patients. Therefore, this article reviews the current advances and existingchallenges in the endoscopic treatment of benign esophageal stricture, with theaim of exploring the possibility of achieving precision and standardization in theendoscopic treatment of this disease.展开更多
From its founding in 1990 as Antarctic Research(English version)to the autumn issue in 2025(this issue),Advances in Polar Science(APS)has published a total of 100 issues,marking the beginning of a new stage in its dev...From its founding in 1990 as Antarctic Research(English version)to the autumn issue in 2025(this issue),Advances in Polar Science(APS)has published a total of 100 issues,marking the beginning of a new stage in its development.The year 2025 is a significant milestone for both global polar research and APS.APS was endorsed by the Asian Forum for Polar Sciences(AFoPS)and initiated cooperation during the 2025 AFoPS annual general meeting in India.APS will support AFoPS in planning and organizing special issues in various fields of polar science and in supporting early-career researchers from Asia in publishing their work.展开更多
This paper provides a systematic review of Matrix-Assisted Laser Desorption/Ionization-Mass Spectrometry Imaging(MALDI-MSI),encompassing its technical principles,experimental workflows,matrix optimization strategies,a...This paper provides a systematic review of Matrix-Assisted Laser Desorption/Ionization-Mass Spectrometry Imaging(MALDI-MSI),encompassing its technical principles,experimental workflows,matrix optimization strategies,and recent advancements in plant science applications.It highlights the method's groundbreaking applications in spatial mapping of plant metabolites,dynamic hormone monitoring,and functional studies of tissue microdomains,while offering critical insights into current technical limitations and future research directions.展开更多
文摘Recent advancements in radiotherapy for esophageal cancer have significantly improved treatment outcomes and patient quality of life.Traditional radiotherapy techniques have been enhanced by the integration of advanced imaging and precision targeting technologies,such as intensity-modulated radiotherapy and proton therapy,which allow for more accurate tumor targeting while minimizing damage to surrounding healthy tissues.Additionally,combining radiotherapy with immunotherapy has shown promising results,leveraging the body’s im-mune response to enhance the effectiveness of cancer treatment.Studies have also highlighted the benefits of neoadjuvant chemoradiation followed by surgical resection,which has been associated with improved overall survival rates com-pared to radiotherapy alone.These innovations are paving the way for more effe-ctive and personalized treatment strategies,offering new hope for patients with esophageal cancer.
基金supported by the National Natural Science Foundation of China(Grant No.52473121,52403370 and 52221006)Fundamental Research Funds for the Central Universities(buctrc202020,buctrc202312).
文摘The intricate hierarchical structure of musculoskeletal tissues,including bone and interface tissues,necessitates the use of complex scaffold designs and material structures to serve as tissue-engineered substitutes.This has led to growing interest in the development of gradient bone scaffolds with hierarchical structures mimicking the extracellular matrix of native tissues to achieve improved therapeutic outcomes.Building on the anatomical characteristics of bone and interfacial tissues,this review provides a summary of current strategies used to design and fabricate biomimetic gradient scaffolds for repairing musculoskeletal tissues,specifically focusing on methods used to construct compositional and structural gradients within the scaffolds.The latest applications of gradient scaffolds for the regeneration of bone,osteochondral,and tendon-to-bone interfaces are presented.Furthermore,the current progress of testing gradient scaffolds in physiologically relevant animal models of skeletal repair is discussed,as well as the challenges and prospects of moving these scaffolds into clinical application for treating musculoskeletal injuries.
文摘《宇航学报》英文版(Advances in Astronautics)由中国宇航学会与哈尔滨工业大学联合主办,与中国宇航学会主办的中文旗舰学术期刊《宇航学报》实施一体化建设,定位于覆盖宇航领域主要技术方向的综合性英文学术期刊。本刊为英文季刊,与施普林格·自然集团合作出版,并已被Ei Compendex、Scopus等权威数据库收录,为全球科研人员提供高质量的成果发表平台。
文摘《宇航学报》英文版(Advances in Astronautics)由中国宇航学会与哈尔滨工业大学联合主办,与中国宇航学会主办的中文旗舰学术期刊《宇航学报》实施一体化建设,定位于覆盖宇航领域主要技术方向的综合性英文学术期刊。本刊为英文季刊,与施普林格·自然集团合作出版,并已被Ei Compendex、Scopus等权威数据库收录,为全球科研人员提供高质量的成果发表平台。
文摘《宇航学报》英文版(Advances in Astronautics)由中国宇航学会与哈尔滨工业大学联合主办,与中国宇航学会主办的中文旗舰学术期刊《宇航学报》实施一体化建设,定位于覆盖宇航领域主要技术方向的综合性英文学术期刊。本刊为英文季刊,与施普林格·自然集团合作出版,并已被Ei Compendex、Scopus等权威数据库收录,为全球科研人员提供高质量的成果发表平台。
文摘《宇航学报》英文版(Advances in Astronautics)由中国宇航学会与哈尔滨工业大学联合主办,与中国宇航学会主办的中文旗舰学术期刊《宇航学报》实施一体化建设,定位于覆盖宇航领域主要技术方向的综合性英文学术期刊。本刊为英文季刊,与施普林格·自然集团合作出版,并已被Ei Compendex、Scopus等权威数据库收录,为全球科研人员提供高质量的成果发表平台。
文摘《宇航学报》英文版(Advances in Astronautics)由中国宇航学会与哈尔滨工业大学联合主办,与中国宇航学会主办的中文旗舰学术期刊《宇航学报》实施一体化建设,定位于覆盖宇航领域主要技术方向的综合性英文学术期刊。本刊为英文季刊,与施普林格·自然集团合作出版,并已被Ei Compendex、Scopus等权威数据库收录,为全球科研人员提供高质量的成果发表平台。
基金Supported by the National Natural Science Foundation of China(71774049).
文摘In recent years,gratitude intervention,as an application method of positive psychology,has gradually attracted the attention of researchers.Gratitude intervention is considered to be an effective psychological intervention,especially in patients with malignant tumors.This study reviews the research progress of gratitude intervention in patients with malignant tumors,focusing on the mechanism,implementation methods,effect evaluation and challenges in clinical application of gratitude intervention,in the hope of providing a theoretical support and practical guideline for future research and practice.
基金financially supported by National Natural Science Foundation of China(No.22161022).
文摘Chromones serve as versatile heterocyclic scaffolds and are common core structural units in a variety of natural products and bioactive organic molecules.This area of research,at the forefront of organic synthesis,has seen remarkable progress in recent years.Among the various synthetic methodologies for accessing chromone scaffolds,the tandem annulation of o-hydroxyaryl enaminones has emerged as a robust and practical strategy.This approach,through direct vinyl C-H bond functionalization of o-hydroxyaryl enaminones,enables the construction of structurally diverse chromones(including 3-substituted chromones,2-substituted chromones,and 2,3-disubstituted chromones)and their derivatives since mid-2019.In this review,we highlight recent advances in the synthesis of various types of chromones and their derivatives,achieved through tandem direct vinyl C-H activation and chromone annulation of o-hydroxyaryl enaminones.
文摘This special issue of the Asian Journal of Andrology is fully dedicated to the thematic area of non-obstructive azoospermia(NOA),one of the most complex and challenging conditions in the realm of andrology,urology,and reproductive medicine.
基金supported by the National Natural Science Foundation of China(22101043)the Fundamental Research Funds for the Central Universities(N2205013,N232410019,N2405013)+3 种基金Natural Science Foundation of Liaoning Province(2023-MSBA-068)the Opening Fund of State Key Laboratory of Heavy Oil Processing(SKLHOP202203006)the Key Laboratory of Functional Molecular Solids,Ministry of Education(FMS2023005)Northeastern University。
文摘The convergence of materials science and biotechnology has catalyzed the development of innovative platforms,including nanotechnology,smart sensors,and supramolecular materials,significantly advancing the progress in the field of life sciences[1−7].Among them,supramolecular materials have garnered increasing attention in life sciences owing to their distinctive self-assembly capabilities and intelligent responsiveness[8−12].
文摘Background:Non-valvular atrial fibrillation(NVAF),the most prevalent cardiac arrhythmia globally,poses a dual challenge of thromboembolic and bleeding risks,with stroke being the most devastating complication.Despite advancements in anticoagulation and rhythm control,patient outcomes remain suboptimal.Aim:This review synthesizes current evidence on the pathophysiological mechanisms,multidimensional management strategies,and emerging innovations in NVAF to inform clinical practice and future research directions.Methods:A systematic literature search was conducted across nine databases(CNKI,Wanfang,SinoMed,VIP,PubMed,Web of Science,Cochrane Library,Embase,and MEDLINE)using combined Medical Subject Headings(MeSH)and free-text terms,including“atrial fibrillation,”“non-valvular atrial fibrillation,”“risk factors,”and“mechanism”(and their Chinese equivalents).Studies on NVAF pathogenesis,therapeutic interventions,and risk stratification tools were analyzed.Results:(1)Risk Factors and Pathophysiology:NVAF progression is driven by hemodynamic stress(e.g.,hypertension),metabolic disorders(e.g.,obesity,diabetes),chronic inflammation,and fibrosis.Biomarkers such as CRP and Galectin-3,along with TGF-β/Smad signaling,are central to atrial remodeling.(2)Anticoagulation Controversies:While NOACs reduce stroke risk compared to warfarin(HR=0.79),challenges persist in extreme body weight populations and drug-drug interactions(e.g.,with P-glycoprotein inhibitors).(3)Left Atrial Appendage Closure(LAAC):LAAC demonstrates non-inferiority to anticoagulation in stroke prevention(HR=0.79)with reduced major bleeding(HR=0.49),though device-related thrombosis(1.8–7%)remains a concern.(4)Precision Medicine:AI-driven models enhance stroke prediction(AUC=0.71;sensitivity 92%),while genotype-guided warfarin dosing shortens INR stabilization by 40%.(5)Lifestyle Interventions:Combined Mediterranean diet and moderate exercise reduce AF burden(HR=0.69)and reverse left atrial enlargement(LAVI reduced by 12%).(6)Multidisciplinary Care:Integrated“heart-brain team”approaches combining LAAC and PFO closure lower annual stroke recurrence from 8.2%to 2.1%,while comprehensive rehabilitation improves functional capacity(6MWD+45 m)and quality of life(SF-36+12 points).Conclusion:NVAF management has evolved from isolated anticoagulation to a multidimensional paradigm integrating genomics,AI,and lifestyle modification.Future priorities include validating long-term outcomes of novel therapies,addressing evidence gaps in special populations,and implementing digitally enabled,cross-disciplinary care models to mitigate the global burden of NVAF-related complications.
文摘On March 27,the National Natural Science Foundation of China(NSFC)released the annual“Top 10 Science Advances of China”for the year 2024.Topping the list was a research that revealed volcanic activities occurring about 2.8 billion years ago on the far side of the Moon,based on samples returned by the Chang’e-6(CE-6)mission,the first successful effort to bring back samples from the lunar farside.
文摘Hyaline Membrane Disease(HMD)in newborns,also known as neonatal respiratory distress syndrome,is a common critical illness in premature infants,with an incidence inversely correlated with gestational age,posing a serious threat to the life and health of newborns.This paper systematically reviews the core pathogenesis of HMD,focusing on the abnormal metabolism of pulmonary surfactant(PS),genetic factors,immature lung development,and the synergistic effects of inflammatory oxidative stress.It highlights the advances in non-invasive ventilation(NIV)therapy for HMD,including the mechanisms of action,clinical application effects,and optimization strategies of mainstream modalities such as nasal continuous positive airway pressure ventilation(NCPAP),nasal intermittent positive pressure ventilation(NIPPV),and heated humidified high-flow nasal cannula ventilation(HHHFNC).The aim is to provide references for standardized clinical treatment.
文摘Dairy wastewater,a kind of high concentration organic wastewater,is produced in large quantities and difficult to treat,and has a negative impact on the ecological environment.In this study,the source,composition,water quality characteristics of dairy wastewater and its impact on the ecological environment were analyzed,and the treatment methods of dairy wastewater at home and abroad in recent years were summarized,in order to provide a reference for the treatment of dairy wastewater.
基金supported by National Natural Science Foundation of China (No. 82370215).
文摘Allogeneic hematopoietic cell transplantation(allo-HCT) remains a cornerstone therapy for severe hematologic malignancies, offering a potential cure when conventional therapies are ineffective. However, not all patients are suitable recipients of allo-HCT, particularly the elderly patients and those with high comorbidity burdens.Furthermore, patients who develop relapse or graft failure after initial transplantation encounter additional challenges when evaluated for a second transplant.
文摘Benign esophageal stricture is characterized by the narrowing of the digestivetract lumen due to multiple factors. Endoscopic treatment is the first treatmentchoice and includes endoscopic dilatation, drug injection, stenosis incision, stentimplantation, stem cell flap transplantation, etc. However, there are currently nospecific clinical standards or guidelines to quantify a series of specific parametersin the treatment of benign esophageal stricture, such as the frequency of drugadministration, dosage, dilation inner diameter, and number of treatments. Thisleads to operator bias in clinical practice and inconsistent treatment outcomesamong patients. Therefore, this article reviews the current advances and existingchallenges in the endoscopic treatment of benign esophageal stricture, with theaim of exploring the possibility of achieving precision and standardization in theendoscopic treatment of this disease.
文摘From its founding in 1990 as Antarctic Research(English version)to the autumn issue in 2025(this issue),Advances in Polar Science(APS)has published a total of 100 issues,marking the beginning of a new stage in its development.The year 2025 is a significant milestone for both global polar research and APS.APS was endorsed by the Asian Forum for Polar Sciences(AFoPS)and initiated cooperation during the 2025 AFoPS annual general meeting in India.APS will support AFoPS in planning and organizing special issues in various fields of polar science and in supporting early-career researchers from Asia in publishing their work.
文摘This paper provides a systematic review of Matrix-Assisted Laser Desorption/Ionization-Mass Spectrometry Imaging(MALDI-MSI),encompassing its technical principles,experimental workflows,matrix optimization strategies,and recent advancements in plant science applications.It highlights the method's groundbreaking applications in spatial mapping of plant metabolites,dynamic hormone monitoring,and functional studies of tissue microdomains,while offering critical insights into current technical limitations and future research directions.
