In 2021,approximately 537 million people suffered from diabetes mellitus(DM)globally,and this figure will increase to approximately 783 million within the next quarter-century.The increasing burden of DM is a pressing...In 2021,approximately 537 million people suffered from diabetes mellitus(DM)globally,and this figure will increase to approximately 783 million within the next quarter-century.The increasing burden of DM is a pressing global public health issue.Therefore,the early identification of high-risk groups and implementation of effective intervention measures is imperative.展开更多
This study aims to systematically explore the differences in health status between empty-nest and non-empty-nest older adults and further analyze the potential impact of empty-nest and non-empty-nest status on their p...This study aims to systematically explore the differences in health status between empty-nest and non-empty-nest older adults and further analyze the potential impact of empty-nest and non-empty-nest status on their physical and mental health.The study surveyed older adult populations in Anhui Province(N=379,average age=69.51 years)to assess their mental and physical health.Correlation analysis,multiple linear regression analysis,and propensity score matching were used to quantify the health differences between empty-nest and non-empty-nest older adults.Multiple linear regression analysis showed that empty-nest status has a significant positive impact on mental health but a negative impact on physical health.Propensity score matching analysis further validated the main findings of the multiple regression analysis.These findings should be interpreted within specific contexts and conditions,considering individual characteristics and historical perspectives,and fully considering the actual circumstances of the respondents.展开更多
To the editor:China is undergoing a profound demo-graphic transition,with the proportion of adults aged 65 and older reaching 14.9%in 2022 and projected to continue rising due to declining birth rates and increased li...To the editor:China is undergoing a profound demo-graphic transition,with the proportion of adults aged 65 and older reaching 14.9%in 2022 and projected to continue rising due to declining birth rates and increased life expectancy.1 This ageing trend has brought mental health in late life into sharp focus as a growing public health issue.展开更多
Objective:This randomized controlled trial aimed to assess the impact of a targeted educational intervention on the awareness and practice of genetic screening and counseling among young adults in Calabar Municipality...Objective:This randomized controlled trial aimed to assess the impact of a targeted educational intervention on the awareness and practice of genetic screening and counseling among young adults in Calabar Municipality,Cross River State.Materials and Methods:Participants(aged 18-45)were randomly assigned to either an intervention group receiving structured health education or a control group receiving general health information.Stratified randomization was used between the groups.A sample size of 340 participants was recruited to detect a 20%difference in outcomes with 80%power.Data were collected using prevalidated questionnaires at baseline,immediately after the intervention,and at a 3-month follow-up.The intervention consisted of three weekly 90-min educational sessions covering genetics,the benefits of screening,and practical guidance on accessing genetic services.The primary outcomes were changes in awareness and practices related to genetic screening,with secondary outcomes focusing on attitudes and intentions toward genetic counseling.Results:Findings revealed that awareness of genetic screening was higher in the intervention group,with 65.9%of participants aware of early detection,compared to 59.4%in the control group,although the difference was not statistically significant(P=0.23).In terms of practice,42.9%of the intervention group and 40.0%of the control group engaged in genetic screening programs,with no significant difference(P=0.57).Logistic regression analysis highlighted that age,educational level,and knowledge of teratogens were significant predictors of genetic screening awareness.Participants aged 36 years and above were 1.52 times more likely to be aware(odds ratio[OR]=1.52,P=0.003),and those with tertiary education had nearly double the likelihood of awareness(OR=1.96,P<0.001).Conclusion:The study underscores the importance of targeted education in improving genetic screening awareness.展开更多
Objectives:This study aimed to develop a mobile frailty management platform for Chinese communitydwelling older adults and evaluate its effectiveness,usability and safety.Methods:Based on literature research,the resea...Objectives:This study aimed to develop a mobile frailty management platform for Chinese communitydwelling older adults and evaluate its effectiveness,usability and safety.Methods:Based on literature research,the research team combined the frailty cycle and integration models,self-determination theory,and technology acceptance models and determined the frailty interventions through expert discussion,then transformed it into multimedia resources,finally,engineers developed the mobile management platform.A cluster sampling,parallel,single-blind,controlled quasiexperimental trial was conducted.Sixty older adults from two community health service centers were recruited from March to August 2023.The control group received routine community care,while the intervention group used the mobile frailty management platform.The incidence of frailty,scores of quality of life,depression,sleep quality,and grip strength within 12 weeks were compared between the two groups,and the availability and safety of the platform were assessed.Results:A total of 52 participants completed the study,27 in the intervention group and 25 in the control group.At 12 weeks after the intervention,the frailty state of the intervention group was reversed to prefrailty.There were no significant differences in the scores of quality of life,depression,sleep quality,and grip strength between the two groups before and 4 weeks after intervention.At 8 weeks and 12 weeks after the intervention,the quality of life,depression,and grip strength of the intervention group were improved with statistical significance(P<0.05).Sleep quality was statistically significant only 12 weeks after the intervention(P<0.05).System Usability Scale score for the platform was(87.96±5.88),indicating a highly satisfactory user experience.Throughout the intervention,no adverse events were reported among the older adults.Conclusions:The mobile frailty management platform effectively improved frailty status,depressive mood,sleep quality,grip strength,and quality of life for Chinese community-dwelling older adults.It holds clinical application value and is an effective tool for strengthening frailty management among Chinese community-dwelling older adults.展开更多
In this editorial,I comment on the article conducted by Yang and Woo.Mental health in older adults remains underserved and underexamined,with final decades shaped by cumulative life stressors,chronic conditions,and so...In this editorial,I comment on the article conducted by Yang and Woo.Mental health in older adults remains underserved and underexamined,with final decades shaped by cumulative life stressors,chronic conditions,and social determinants that disproportionately affect marginalized communities.In this study,I would like to synthesize current evidence on the prevalence,presentation,and trajectories of mental health concerns among older adults,highlighting common challenges such as late-life depression,anxiety,cognitive concerns,and underutilization of care.I am going to examine barriers to outreach and treatment,including stigma,cultural and linguistic mismatches,access limitations,and gaps in geriatric mental health services.The analysis in the paper identifies promising pathways to improve outcomes:Community-engaged interventions,culturally tailored care models,integration of mental health with primary and geriatric care,and policy reforms to expand coverage and reduce disparities.As a conclusion,with actionable recommendations for clinicians,researchers,policymakers,and community organizations to break the silence,enhance early detection,and foster resilient aging through equitable,person-centered approaches.展开更多
Addiction literacy equips older adults with the knowledge to navigate substance use risks amid unique challenges like polypharmacy and social isolation.With rising trends in cannabis use among this group,targeted educ...Addiction literacy equips older adults with the knowledge to navigate substance use risks amid unique challenges like polypharmacy and social isolation.With rising trends in cannabis use among this group,targeted education can promote safe practices and reduce preventable harms.By fostering open conversations and integrating addiction literacy into healthcare,providers can support informed decision-making.展开更多
BACKGROUND Human beings,by nature,have many expectations that create a feeling of anxiety about the future,but they are endured and long-ranged.They expect to have relationships with others and need to perceive an emo...BACKGROUND Human beings,by nature,have many expectations that create a feeling of anxiety about the future,but they are endured and long-ranged.They expect to have relationships with others and need to perceive an emotional interest,an interpersonal bond,and sustainment to continue living.Perceiving this link is required for feelings of belongingness,which decreases future anxiety.AIM To investigate the future anxiety and belongingness of young and older adults and determine their relationships.METHODS The study was conducted with 404 volunteer participants.Data were collected using the demographic characteristics from the“Dark Future Scale”and“General Belongingness Scale”.RESULTS The mean age of older adults was 66.76±3.74,while that of younger adults was 36.72±10.12.The average score for“future anxiety”was 18.81±7.59,and for“general belongingness",it was 63.31±1.40.Findings indicated a reverse correlation between future anxiety and belongingness.A significant difference in belonging scores was observed between young and older adults(P=0.016,which is<0.05),whereas no significant difference was found regarding future anxiety scores(P>0.05).CONCLUSION Participants had a moderate level of“future anxiety”and higher“belongingness”.Lower belongingness scores correlated with increased future anxiety.Older adults reported a lower sense of belonging than younger individuals.展开更多
Evidence on the association between osteoporosis and dementia is not fully clear.This study aimed to investigate the potential association between osteoporosis and the subsequent risk of dementia among older adults.We...Evidence on the association between osteoporosis and dementia is not fully clear.This study aimed to investigate the potential association between osteoporosis and the subsequent risk of dementia among older adults.We performed a cohort study of176150 community-dwelling older adults aged≥65 years and free of cognitive impairment between 2018 and 2022 using integrated healthcare data from Shenzhen,China.Diagnoses of osteoporosis,osteoporotic fractures,and dementia were identified through linked outpatient and inpatient medical records and death registration records.Multivariate Cox proportional hazards models were used to estimate the adjusted hazard ratios(HRs)and 95%confidence intervals(CIs)of incident dementia associated with osteoporosis and osteoporotic fractures.The mean(SD)age of the total study population was 70.7(5.4)years,and 9605 had a previous diagnosis of osteoporosis.Over a median follow-up of 2.2(IQR:1.8–4.3,maximum:5.5)years,corresponding to 505423person-years at risk,1367 incident all-cause dementia cases,including 617 Alzheimer's disease and 298 vascular dementia cases,occurred.Physician-diagnosed osteoporosis was associated with a higher risk of all-cause dementia(HR:1.80,95%CI:1.53–2.12).The increased dementia risk tended to be more prominent among patients with osteoporotic fractures(HR:2.43,95%CI:1.83–3.23)than those without(HR:1.63,95%CI:1.35–1.97).Results were similar for Alzheimer's disease and vascular dementia.This study provides evidence that older adults with osteoporosis,especially those with osteoporotic fractures,have an elevated risk of incident dementia.Effective prevention and management of osteoporosis among the older population may be promising to mitigate the dual burden of osteoporosis and dementia.展开更多
BACKGROUND Working memory serves as a fundamental cognitive function that substantially impacts performance in various cognitive tasks.Extensive neurophysiological research has established that theta oscillations(4-8 ...BACKGROUND Working memory serves as a fundamental cognitive function that substantially impacts performance in various cognitive tasks.Extensive neurophysiological research has established that theta oscillations(4-8 Hz)play an essential role in supporting working memory operations.Theta-band transcranial alternating current stimulation(tACS)offers a potential mechanism for working memory enhancement through direct modulation of these fundamental neural oscillations.Nevertheless,current empirical evidence shows substantial variability in the observed effects of theta-tACS across studies.AIM To conduct a systematic review and meta-analysis evaluating the effects of thetatACS on working memory performance in healthy adults.METHODS A systematic literature search was performed on PubMed,EMBASE,and Web of Science up to March 10,2025.Effect sizes were computed using Hedges’g with 95%confidence intervals(CIs),with separate meta-analyses for all included studies and for distinct working memory paradigms[n-back and delayed matchto-sample(DMTS)tasks]to examine potential task-specific effects.Subgroup analyses and meta-regression were performed to evaluate the influence of key moderating variables.RESULTS The systematic review included 21 studies(67 effect sizes).Initial meta-analysis showed theta-tACS moderately improved working memory(Hedges’g=0.405,95%CI:0.212-0.598).However,this effect became nonsignificant after correcting for publication bias(trim-and-fill adjusted Hedges’g=0.082,95%CI:-0.052 to 0.217).Task-specific analyses revealed significant benefits in n-back tasks(Hedges’g=0.463,95%CI:0.193-0.733)but not in DMTS tasks(Hedges’g=0.257,95%CI:-0.186 to 0.553).Moderator analyses showed that performance in n-back tasks was influenced by stimulation frequency(P=0.001),concurrent status(P=0.014),task modality(P=0.005),and duration(P=0.013),whereas only the region of targeted stimulation(P=0.012)moderated DMTS tasks.CONCLUSION Theta-tACS enhances working memory in healthy adults,with effects modulated by the task type and protocol parameters,offering dual implications for cognitive enhancement and clinical interventions.展开更多
Subjective well-being is a key indicator of quality of life and a crucial factor for successful aging among older adults.However,few studies have explored the subjective well-being among older adults from the perspect...Subjective well-being is a key indicator of quality of life and a crucial factor for successful aging among older adults.However,few studies have explored the subjective well-being among older adults from the perspective of digital literacy.Therefore,this study explores the relationship between digital literacy and subjective well-being using data on 4270 older adults from the 2020 China Family Panel Studies(CFPS)dataset.PROCESS mediation analysis results indicated digital literacy is associated with higher subjective well-being among the older adults.Digital literacy was associated with the frequency of physical exercise and consumption.Moreover,Digital literacy can also enhance the subjective well-being among older adults by increasing the frequency of physical exercise,and consumption,and a chain mediator subjective well-being.These findings align with the theoretical framework of digital health literacy.Theory which posits that health information obtained through digital literacy can help older adults better engage in healthy lifestyles,thereby enhancing their quality of life.These findings hold significant practical implications for enhancing the subjective well-being among older adults and advancing the development of successful aging.展开更多
Background:Platform algorithms driving content presentation are profoundly shaping the experience of younger users.While prior research has examined anxiety stemming from young adults’social media usage,the link betw...Background:Platform algorithms driving content presentation are profoundly shaping the experience of younger users.While prior research has examined anxiety stemming from young adults’social media usage,the link between upward social comparison and anxiety remains unclear.This study aims to investigate the mediating role of upward social comparison in this relationship and determine the moderating role of psychological resilience.Methods:A cross-sectional survey was conducted among 562 young Chinese adults aged 18–35(53%female).Data were collected via an online questionnaire employing validated measurement instruments,including scales for social media usage patterns,upward comparator behaviour(INCOM),anxiety levels(GAD-7),and psychological resilience(RSA).Correlation analysis,mediation analysis,and moderation analysis were conducted using SPSS 29.0.Results:As predicted,the results indicate that upward social comparison mediates the relationship between both active(β=−0.11,95%CI=[−0.15,−0.08])and passive(β=0.11,95%CI=[0.07,0.15])social media use and anxiety.Furthermore,psychological resilience(β_(low)=0.10,95%CI=[0.06,0.14];β_(high)=0.05,95%CI=[0.01,0.09])moderated the indirect effect of passive social media use on anxiety through upward social comparison.Conclusion:The findings indicate that upward social comparison significantly influences the anxiety experienced by young social media users,with psychological resilience playing a crucial moderating role.These results offer valuable insights for optimizing content recommendation algorithms on social media platforms to better support young adults’mental health.展开更多
Objective:To study the effects of fall prevention program for the community-dwelling older adults.Falling is a significant risk factor for older adults,impacting their physical and mental health and causing social and...Objective:To study the effects of fall prevention program for the community-dwelling older adults.Falling is a significant risk factor for older adults,impacting their physical and mental health and causing social and economic burdens on themselves and their families.Methods:A randomized controlled trial was conducted with 60 older adults aged 60 years and older attending the elderly schools in Chanthaburi province,Thailand.Two elderly schools were randomly selected from 24 schools using a lottery method,then were randomly assigned to either the intervention or the control trial setting.Eligible older adults from each elderly school were randomly selected to participate in the study using a computer generator.There were 30 participants in each group.The experimental group engaged in fall prevention program training for 2 h per session per week for 6 weeks.The control group attended usual health-related activities of the school.Outcome measures before and after the intervention included:questionnaires used to assess knowledge and behaviors of fall prevention,the Fear of Falling test(Short FES-I),the Timed Up and Go Test(TUGT),and the Thai Falls Risk Assessment Test(Thai-FRAT).Results:The independent t-tests revealed significant differences between the experimental group and the control group.Post-intervention showed that the experimental group demonstrated better knowledge(t=5.94,P<0.001)and behaviors related to the fall prevention program knowledge(t=4.63,P<0.001),reduced fear of falling(t=-4.72,P<0.001),improved walking and balance(t=-4.85,P<0.001)and lowered risk of falling(t=-4.02,P<0.001)than the control group.Conclusions:The fall prevention program could benefit the older adults dwellings in the community by increasing their knowledge and fall prevention behaviors,reducing their fear of falling and fall risk and improving their walking and balance,which would enhance their quality of life.展开更多
Economic inequality is a persistent global issue with profound implications for mental health,particularly among older adults.Previous studies have largely focused on objective economic well-being indicators such as i...Economic inequality is a persistent global issue with profound implications for mental health,particularly among older adults.Previous studies have largely focused on objective economic well-being indicators such as income,employment status,and poverty.While these factors are crucial,emerging evidence suggests that welfare benefits and subjective economic well-being components of what can be deemed augmented economic well-being,may play equally significant roles in shaping psychological health among aging populations.This research explores how disparities in these aspects contribute to psychological distress in older adults.We highlight the role of financial security,government assistance pro-grams,and personal economic satisfaction.We propose policy interventions to mitigate adverse effects and emphasize the need for a holistic approach to econo-mic well-being to improve mental health outcomes in older adults.This study reveals that subjective financial security and access to welfare benefits often surpass income as predictors of mental health.These insights underscore the importance of broadening economic frameworks in aging research and deve-loping integrated policies to enhance financial and psychological well-being.展开更多
Objective To examine the mechanistic of organochlorine-associated changes in lung function.Methods This study investigated 76 healthy older adults in Jinan,Shandong Province,over a fivemonth period.Personal exposure t...Objective To examine the mechanistic of organochlorine-associated changes in lung function.Methods This study investigated 76 healthy older adults in Jinan,Shandong Province,over a fivemonth period.Personal exposure to organochlorines was quantified using wearable passive samplers,while inflammatory factors and thyroid hormones were analyzed from blood samples.Participants’lung function was evaluated.After stratifying participants according to their thyroid hormone levels,we analyzed the differential effects of organochlorine exposure on lung function and inflammatory factors across the low and high thyroid hormone groups.Mediation analysis was further conducted to elucidate the relationships among organochlorine exposures,inflammatory factors,and lung function.Results Bis(2-chloro-1-methylethyl)ether(BCIE),was negatively associated with forced vital capacity(FVC,–2.05%,95%CI:–3.11%to–0.97%),and associated with changes in inflammatory factors such as interleukin(IL)-2,IL-7,IL-8,and IL-13 in the low thyroid hormone group.The mediation analysis indicated a mediating effect of IL-2(15.63%,95%CI:0.91%to 44.64%)and IL-13(13.94%,95%CI:0.52%to 41.07%)in the association between BCIE exposure and FVC.Conclusion Lung function and inflammatory factors exhibited an increased sensitivity to organochlorine exposure at lower thyroid hormone levels,with inflammatory factors potentially mediating the adverse effects of organochlorines on lung function.展开更多
Background:Patient participation is crucial for medication safety among older adults with chronic diseases transitioning from hospital to home,yet evidence on its levels and influencing factors remains limited.This st...Background:Patient participation is crucial for medication safety among older adults with chronic diseases transitioning from hospital to home,yet evidence on its levels and influencing factors remains limited.This study investigated the current state and predictors of such participation during this critical period.Methods:A cross-sectional study was conducted among older adults discharged from two tertiary hospitals in Fujian,China(October-December 2023).Data were collected using a general information questionnaire,a self-developed behavior scale,the Health Literacy Management Scale,General Self-Efficacy Scale,Facilitation of Patient Involvement Scale,and Family Support Scale.Analyses included ANOVA,Pearson correlation,and multiple stepwise regression.Results:Among 302 valid responses,the mean score for participation in medication safety behaviors was 68.59±11.62,indicating a moderate level.Health literacy,self-efficacy,healthcare worker support,and family support were positively correlated with participation(all P<0.01).Multiple regression identified daily medication frequency,health literacy,self-efficacy,and healthcare worker support as significant predictors,explaining 18.3%of the variance.Conclusion:Participation in medication safety among older chronic disease patients during care transitions requires improvement.Enhancing health literacy,self-efficacy,and healthcare worker support,while considering medication frequency,can promote patient involvement and medication safety.展开更多
Hypertension,a prevalent condition among older adults,has been identified as a risk factor for cognitive decline.Nutritional status is a pivotal factor in preserving cognitive function in hypertensive older adults.Nut...Hypertension,a prevalent condition among older adults,has been identified as a risk factor for cognitive decline.Nutritional status is a pivotal factor in preserving cognitive function in hypertensive older adults.Nutritional psychiatry underscores the significance of anti-inflammatory diets in promoting mental and cognitive health.This article examined the mechanisms by which body mass index,serum hemoglobin,serum albumin,and alkaline phosphatase levels predict cognitive function in hypertensive older adults.Nutrition emerges as a modifiable factor that can be targeted to maintain cognitive function in these patients.展开更多
In the December 2025 issue of the Journal of Sport and Health Science,Tomkinson et al.^(1)present international norms for adult handgrip strength(HGS)developed from a systematic review of 100 studies with 2.4 million ...In the December 2025 issue of the Journal of Sport and Health Science,Tomkinson et al.^(1)present international norms for adult handgrip strength(HGS)developed from a systematic review of 100 studies with 2.4 million adults aged 20 to 100+years from 69 countries and regions.Twenty-eight interna-tional handGRIP Strength(iGRIPS)researchers contributed to the study.展开更多
Background:The aging global population necessitates innovative strategies to enhance older adults’health and quality of life.Physical activity(PA)is crucial for healthy aging,yet many older adults struggle to exercis...Background:The aging global population necessitates innovative strategies to enhance older adults’health and quality of life.Physical activity(PA)is crucial for healthy aging,yet many older adults struggle to exercise regularly.Artificial intelligence(AI)-powered social robots offer an interactive,engaging,and personalized solution to promote PA among this demographic.This systematic review investigated the role of AI-powered social robots in encouraging PA in older adults.Methods:We conducted a systematic literature search in databases including PubMed,IEEE Xplore,Scopus,Cochrane Library,and Web of Science,focusing on studies published until February 2024.We included peer-reviewed articles reporting empiricalfindings on designing,implementing,and evaluating AI-enabled social robots to promote PA among older adults.Studies were conducted in nursing homes,rehabilita-tion centers,community centers,and home environments.Results:A total of 19 studies were included in the review.Analysis reveals that AI-powered social robots effectively motivate older adults to engage in PAs,leading to increased exercise adherence,higher engagement levels,and extended training durations.Social robots have demon-strated effectiveness across various environments,including nursing homes,rehabilitation centers,community centers,home environments,and elder care facilities.In structured environments like nursing homes and rehabilitation centers,robots help maintain regular exercise routines,improving adherence and recovery outcomes.In community and elder care centers,robots promote PA and social engagement by facilitating group exercises and enhancing participation.In home environments,robots provide personalized support for daily activities,offering reminders and engagement,which fosters long-term activity engagement.User acceptance and satisfaction are high,with participantsfinding the robots engaging and enjoyable.Additionally,several studies indicate potential health benefits,such as improved medication adherence,better sleep patterns,and enhanced overall well-being.Nevertheless,additional research is imperative to address unresolved issues concerning the technolog-ical maintenance costs,design constraints,and adaptability of AI-powered social robots to specific user demographics.Conclusion:AI-powered social robots play a promising role in promoting PA among older adults,enhancing their health,well-being,and inde-pendence.This review provides insights for researchers,designers,and healthcare professionals developing AI-enabled social robotic systems for older adults.展开更多
Objective: To explore the association between cardiometabolic multimorbidity and frailty among middle- aged and older adults in China. Methods: Data were derived from the 2013 wave of the China Longitudinal Healthy Lo...Objective: To explore the association between cardiometabolic multimorbidity and frailty among middle- aged and older adults in China. Methods: Data were derived from the 2013 wave of the China Longitudinal Healthy Longevity Survey, including a total of 6,179 individuals aged 45 years and above with complete follow-up records. Basic demographic information was collected, and frailty status was assessed using a physical frailty scale. Generalized linear models were employed to analyze the association between the number and combinations of cardiometabolic conditions- such as hypertension, diabetes, heart disease, and stroke-and frailty. Results: The prevalence of cardiometabolic multimorbidity among middle-aged and older adults was 14.23%. After adjusting for sociodemographic covariates, individuals with cardiometabolic multimorbidity had a significantly increased risk of frailty compared to those without such conditions (OR = 1.78, 95% CI: 1.45-2.19), along with higher frailty scale scores (β = 0.26, 95% CI: 0.19-0.34). Compared to individuals without cardiometabolic diseases, those with both hypertension and stroke (OR = 1.18, 95% CI: 1.06-1.31) and those with hypertension, heart disease, and stroke (OR = 1.46, 95% CI: 1.24-1.73) exhibited notably higher frailty risks. Conclusion: There is a significant association between cardiometabolic multimorbidity and frailty in middle- aged and older adults in China, particularly for comorbidity patterns involving hypertension. These findings provide evidence for developing targeted health interventions for aging populations.展开更多
基金supported by the Research Funds of the Center for Big Data and Population Health of IHM(grant number JKS2022015)the Key Scientific Research Fund of the Anhui Provincial Education Department(grant number2023AH050610)the Anhui Natural Science Foundation(grant number 1808085QH252)。
文摘In 2021,approximately 537 million people suffered from diabetes mellitus(DM)globally,and this figure will increase to approximately 783 million within the next quarter-century.The increasing burden of DM is a pressing global public health issue.Therefore,the early identification of high-risk groups and implementation of effective intervention measures is imperative.
基金Shanghai Philosophy and Social Science Planning General Project“Research on the Mechanism of Population Aging in the Yangtze River Delta Urban Agglomeration on Economic Growth”(2023ZSH002).
文摘This study aims to systematically explore the differences in health status between empty-nest and non-empty-nest older adults and further analyze the potential impact of empty-nest and non-empty-nest status on their physical and mental health.The study surveyed older adult populations in Anhui Province(N=379,average age=69.51 years)to assess their mental and physical health.Correlation analysis,multiple linear regression analysis,and propensity score matching were used to quantify the health differences between empty-nest and non-empty-nest older adults.Multiple linear regression analysis showed that empty-nest status has a significant positive impact on mental health but a negative impact on physical health.Propensity score matching analysis further validated the main findings of the multiple regression analysis.These findings should be interpreted within specific contexts and conditions,considering individual characteristics and historical perspectives,and fully considering the actual circumstances of the respondents.
基金supported by the National Natural Science Foundation of China(72364004)the Guangxi Natural Science Foundation(2021JJA180017)+4 种基金National Key Research and Development Program of China(2023YFC2506202)Fundamental Research Funds for the Central Universities(project number YG2024ZD25)Three-year action plan for Shanghai's public health system construction(GWVI-2.1.4)Projects of Guangxi Philosophy and Social Science Research(23FGL038)Guangxi Key Research Base of Humanities and Social Sciences in Universities-Research Center for Health and Economic&Social Development(2025RWB13).
文摘To the editor:China is undergoing a profound demo-graphic transition,with the proportion of adults aged 65 and older reaching 14.9%in 2022 and projected to continue rising due to declining birth rates and increased life expectancy.1 This ageing trend has brought mental health in late life into sharp focus as a growing public health issue.
文摘Objective:This randomized controlled trial aimed to assess the impact of a targeted educational intervention on the awareness and practice of genetic screening and counseling among young adults in Calabar Municipality,Cross River State.Materials and Methods:Participants(aged 18-45)were randomly assigned to either an intervention group receiving structured health education or a control group receiving general health information.Stratified randomization was used between the groups.A sample size of 340 participants was recruited to detect a 20%difference in outcomes with 80%power.Data were collected using prevalidated questionnaires at baseline,immediately after the intervention,and at a 3-month follow-up.The intervention consisted of three weekly 90-min educational sessions covering genetics,the benefits of screening,and practical guidance on accessing genetic services.The primary outcomes were changes in awareness and practices related to genetic screening,with secondary outcomes focusing on attitudes and intentions toward genetic counseling.Results:Findings revealed that awareness of genetic screening was higher in the intervention group,with 65.9%of participants aware of early detection,compared to 59.4%in the control group,although the difference was not statistically significant(P=0.23).In terms of practice,42.9%of the intervention group and 40.0%of the control group engaged in genetic screening programs,with no significant difference(P=0.57).Logistic regression analysis highlighted that age,educational level,and knowledge of teratogens were significant predictors of genetic screening awareness.Participants aged 36 years and above were 1.52 times more likely to be aware(odds ratio[OR]=1.52,P=0.003),and those with tertiary education had nearly double the likelihood of awareness(OR=1.96,P<0.001).Conclusion:The study underscores the importance of targeted education in improving genetic screening awareness.
文摘Objectives:This study aimed to develop a mobile frailty management platform for Chinese communitydwelling older adults and evaluate its effectiveness,usability and safety.Methods:Based on literature research,the research team combined the frailty cycle and integration models,self-determination theory,and technology acceptance models and determined the frailty interventions through expert discussion,then transformed it into multimedia resources,finally,engineers developed the mobile management platform.A cluster sampling,parallel,single-blind,controlled quasiexperimental trial was conducted.Sixty older adults from two community health service centers were recruited from March to August 2023.The control group received routine community care,while the intervention group used the mobile frailty management platform.The incidence of frailty,scores of quality of life,depression,sleep quality,and grip strength within 12 weeks were compared between the two groups,and the availability and safety of the platform were assessed.Results:A total of 52 participants completed the study,27 in the intervention group and 25 in the control group.At 12 weeks after the intervention,the frailty state of the intervention group was reversed to prefrailty.There were no significant differences in the scores of quality of life,depression,sleep quality,and grip strength between the two groups before and 4 weeks after intervention.At 8 weeks and 12 weeks after the intervention,the quality of life,depression,and grip strength of the intervention group were improved with statistical significance(P<0.05).Sleep quality was statistically significant only 12 weeks after the intervention(P<0.05).System Usability Scale score for the platform was(87.96±5.88),indicating a highly satisfactory user experience.Throughout the intervention,no adverse events were reported among the older adults.Conclusions:The mobile frailty management platform effectively improved frailty status,depressive mood,sleep quality,grip strength,and quality of life for Chinese community-dwelling older adults.It holds clinical application value and is an effective tool for strengthening frailty management among Chinese community-dwelling older adults.
文摘In this editorial,I comment on the article conducted by Yang and Woo.Mental health in older adults remains underserved and underexamined,with final decades shaped by cumulative life stressors,chronic conditions,and social determinants that disproportionately affect marginalized communities.In this study,I would like to synthesize current evidence on the prevalence,presentation,and trajectories of mental health concerns among older adults,highlighting common challenges such as late-life depression,anxiety,cognitive concerns,and underutilization of care.I am going to examine barriers to outreach and treatment,including stigma,cultural and linguistic mismatches,access limitations,and gaps in geriatric mental health services.The analysis in the paper identifies promising pathways to improve outcomes:Community-engaged interventions,culturally tailored care models,integration of mental health with primary and geriatric care,and policy reforms to expand coverage and reduce disparities.As a conclusion,with actionable recommendations for clinicians,researchers,policymakers,and community organizations to break the silence,enhance early detection,and foster resilient aging through equitable,person-centered approaches.
基金Supported by FAPESP and Conselho Nacional de Desenvolvimento Cientifico e Tecnologico,No.2024/13209-0.
文摘Addiction literacy equips older adults with the knowledge to navigate substance use risks amid unique challenges like polypharmacy and social isolation.With rising trends in cannabis use among this group,targeted education can promote safe practices and reduce preventable harms.By fostering open conversations and integrating addiction literacy into healthcare,providers can support informed decision-making.
文摘BACKGROUND Human beings,by nature,have many expectations that create a feeling of anxiety about the future,but they are endured and long-ranged.They expect to have relationships with others and need to perceive an emotional interest,an interpersonal bond,and sustainment to continue living.Perceiving this link is required for feelings of belongingness,which decreases future anxiety.AIM To investigate the future anxiety and belongingness of young and older adults and determine their relationships.METHODS The study was conducted with 404 volunteer participants.Data were collected using the demographic characteristics from the“Dark Future Scale”and“General Belongingness Scale”.RESULTS The mean age of older adults was 66.76±3.74,while that of younger adults was 36.72±10.12.The average score for“future anxiety”was 18.81±7.59,and for“general belongingness",it was 63.31±1.40.Findings indicated a reverse correlation between future anxiety and belongingness.A significant difference in belonging scores was observed between young and older adults(P=0.016,which is<0.05),whereas no significant difference was found regarding future anxiety scores(P>0.05).CONCLUSION Participants had a moderate level of“future anxiety”and higher“belongingness”.Lower belongingness scores correlated with increased future anxiety.Older adults reported a lower sense of belonging than younger individuals.
基金supported by the Shenzhen Medical Academy of Research and Translation(Grant C2302001)the Noncommunicable Chronic Diseases-National Science and Technology Major Project(Grant 2023ZD0503500)+5 种基金the National Natural Science Foundation of China(Grants 82030102,12126602)the Shenzhen Science and Technology Innovation Committee(No.ZDSYS20200810171403013)the Talents enlisted in major talent programs of Guangdong Province(20210N020921)the Shenzhen Development and Reform Committee(No.XMHT20230108022)the Medical Research Innovation Project(Grant G030410001)the Shenzhen Medical Research Funds(Grant A2402041)。
文摘Evidence on the association between osteoporosis and dementia is not fully clear.This study aimed to investigate the potential association between osteoporosis and the subsequent risk of dementia among older adults.We performed a cohort study of176150 community-dwelling older adults aged≥65 years and free of cognitive impairment between 2018 and 2022 using integrated healthcare data from Shenzhen,China.Diagnoses of osteoporosis,osteoporotic fractures,and dementia were identified through linked outpatient and inpatient medical records and death registration records.Multivariate Cox proportional hazards models were used to estimate the adjusted hazard ratios(HRs)and 95%confidence intervals(CIs)of incident dementia associated with osteoporosis and osteoporotic fractures.The mean(SD)age of the total study population was 70.7(5.4)years,and 9605 had a previous diagnosis of osteoporosis.Over a median follow-up of 2.2(IQR:1.8–4.3,maximum:5.5)years,corresponding to 505423person-years at risk,1367 incident all-cause dementia cases,including 617 Alzheimer's disease and 298 vascular dementia cases,occurred.Physician-diagnosed osteoporosis was associated with a higher risk of all-cause dementia(HR:1.80,95%CI:1.53–2.12).The increased dementia risk tended to be more prominent among patients with osteoporotic fractures(HR:2.43,95%CI:1.83–3.23)than those without(HR:1.63,95%CI:1.35–1.97).Results were similar for Alzheimer's disease and vascular dementia.This study provides evidence that older adults with osteoporosis,especially those with osteoporotic fractures,have an elevated risk of incident dementia.Effective prevention and management of osteoporosis among the older population may be promising to mitigate the dual burden of osteoporosis and dementia.
基金Supported by Shanghai Municipal Health Commission’s Special Clinical Research Project for the Hygiene Industry,No.20244Y0041Youth Initiation Fund of Naval Medical University,No.2023QN028 and No.2023QN030。
文摘BACKGROUND Working memory serves as a fundamental cognitive function that substantially impacts performance in various cognitive tasks.Extensive neurophysiological research has established that theta oscillations(4-8 Hz)play an essential role in supporting working memory operations.Theta-band transcranial alternating current stimulation(tACS)offers a potential mechanism for working memory enhancement through direct modulation of these fundamental neural oscillations.Nevertheless,current empirical evidence shows substantial variability in the observed effects of theta-tACS across studies.AIM To conduct a systematic review and meta-analysis evaluating the effects of thetatACS on working memory performance in healthy adults.METHODS A systematic literature search was performed on PubMed,EMBASE,and Web of Science up to March 10,2025.Effect sizes were computed using Hedges’g with 95%confidence intervals(CIs),with separate meta-analyses for all included studies and for distinct working memory paradigms[n-back and delayed matchto-sample(DMTS)tasks]to examine potential task-specific effects.Subgroup analyses and meta-regression were performed to evaluate the influence of key moderating variables.RESULTS The systematic review included 21 studies(67 effect sizes).Initial meta-analysis showed theta-tACS moderately improved working memory(Hedges’g=0.405,95%CI:0.212-0.598).However,this effect became nonsignificant after correcting for publication bias(trim-and-fill adjusted Hedges’g=0.082,95%CI:-0.052 to 0.217).Task-specific analyses revealed significant benefits in n-back tasks(Hedges’g=0.463,95%CI:0.193-0.733)but not in DMTS tasks(Hedges’g=0.257,95%CI:-0.186 to 0.553).Moderator analyses showed that performance in n-back tasks was influenced by stimulation frequency(P=0.001),concurrent status(P=0.014),task modality(P=0.005),and duration(P=0.013),whereas only the region of targeted stimulation(P=0.012)moderated DMTS tasks.CONCLUSION Theta-tACS enhances working memory in healthy adults,with effects modulated by the task type and protocol parameters,offering dual implications for cognitive enhancement and clinical interventions.
文摘Subjective well-being is a key indicator of quality of life and a crucial factor for successful aging among older adults.However,few studies have explored the subjective well-being among older adults from the perspective of digital literacy.Therefore,this study explores the relationship between digital literacy and subjective well-being using data on 4270 older adults from the 2020 China Family Panel Studies(CFPS)dataset.PROCESS mediation analysis results indicated digital literacy is associated with higher subjective well-being among the older adults.Digital literacy was associated with the frequency of physical exercise and consumption.Moreover,Digital literacy can also enhance the subjective well-being among older adults by increasing the frequency of physical exercise,and consumption,and a chain mediator subjective well-being.These findings align with the theoretical framework of digital health literacy.Theory which posits that health information obtained through digital literacy can help older adults better engage in healthy lifestyles,thereby enhancing their quality of life.These findings hold significant practical implications for enhancing the subjective well-being among older adults and advancing the development of successful aging.
文摘Background:Platform algorithms driving content presentation are profoundly shaping the experience of younger users.While prior research has examined anxiety stemming from young adults’social media usage,the link between upward social comparison and anxiety remains unclear.This study aims to investigate the mediating role of upward social comparison in this relationship and determine the moderating role of psychological resilience.Methods:A cross-sectional survey was conducted among 562 young Chinese adults aged 18–35(53%female).Data were collected via an online questionnaire employing validated measurement instruments,including scales for social media usage patterns,upward comparator behaviour(INCOM),anxiety levels(GAD-7),and psychological resilience(RSA).Correlation analysis,mediation analysis,and moderation analysis were conducted using SPSS 29.0.Results:As predicted,the results indicate that upward social comparison mediates the relationship between both active(β=−0.11,95%CI=[−0.15,−0.08])and passive(β=0.11,95%CI=[0.07,0.15])social media use and anxiety.Furthermore,psychological resilience(β_(low)=0.10,95%CI=[0.06,0.14];β_(high)=0.05,95%CI=[0.01,0.09])moderated the indirect effect of passive social media use on anxiety through upward social comparison.Conclusion:The findings indicate that upward social comparison significantly influences the anxiety experienced by young social media users,with psychological resilience playing a crucial moderating role.These results offer valuable insights for optimizing content recommendation algorithms on social media platforms to better support young adults’mental health.
基金supported by Faculty of Nursing,Rambhai Barni Rajabhat University,Thailand.
文摘Objective:To study the effects of fall prevention program for the community-dwelling older adults.Falling is a significant risk factor for older adults,impacting their physical and mental health and causing social and economic burdens on themselves and their families.Methods:A randomized controlled trial was conducted with 60 older adults aged 60 years and older attending the elderly schools in Chanthaburi province,Thailand.Two elderly schools were randomly selected from 24 schools using a lottery method,then were randomly assigned to either the intervention or the control trial setting.Eligible older adults from each elderly school were randomly selected to participate in the study using a computer generator.There were 30 participants in each group.The experimental group engaged in fall prevention program training for 2 h per session per week for 6 weeks.The control group attended usual health-related activities of the school.Outcome measures before and after the intervention included:questionnaires used to assess knowledge and behaviors of fall prevention,the Fear of Falling test(Short FES-I),the Timed Up and Go Test(TUGT),and the Thai Falls Risk Assessment Test(Thai-FRAT).Results:The independent t-tests revealed significant differences between the experimental group and the control group.Post-intervention showed that the experimental group demonstrated better knowledge(t=5.94,P<0.001)and behaviors related to the fall prevention program knowledge(t=4.63,P<0.001),reduced fear of falling(t=-4.72,P<0.001),improved walking and balance(t=-4.85,P<0.001)and lowered risk of falling(t=-4.02,P<0.001)than the control group.Conclusions:The fall prevention program could benefit the older adults dwellings in the community by increasing their knowledge and fall prevention behaviors,reducing their fear of falling and fall risk and improving their walking and balance,which would enhance their quality of life.
文摘Economic inequality is a persistent global issue with profound implications for mental health,particularly among older adults.Previous studies have largely focused on objective economic well-being indicators such as income,employment status,and poverty.While these factors are crucial,emerging evidence suggests that welfare benefits and subjective economic well-being components of what can be deemed augmented economic well-being,may play equally significant roles in shaping psychological health among aging populations.This research explores how disparities in these aspects contribute to psychological distress in older adults.We highlight the role of financial security,government assistance pro-grams,and personal economic satisfaction.We propose policy interventions to mitigate adverse effects and emphasize the need for a holistic approach to econo-mic well-being to improve mental health outcomes in older adults.This study reveals that subjective financial security and access to welfare benefits often surpass income as predictors of mental health.These insights underscore the importance of broadening economic frameworks in aging research and deve-loping integrated policies to enhance financial and psychological well-being.
基金supported by the National Key Research and Development Program of China(No.2022YFC3702700)the National Natural Science Foundation of China(No.82025030)the National Research Program for Key Issues in Air Pollution Control of China(No.DQGG0401)。
文摘Objective To examine the mechanistic of organochlorine-associated changes in lung function.Methods This study investigated 76 healthy older adults in Jinan,Shandong Province,over a fivemonth period.Personal exposure to organochlorines was quantified using wearable passive samplers,while inflammatory factors and thyroid hormones were analyzed from blood samples.Participants’lung function was evaluated.After stratifying participants according to their thyroid hormone levels,we analyzed the differential effects of organochlorine exposure on lung function and inflammatory factors across the low and high thyroid hormone groups.Mediation analysis was further conducted to elucidate the relationships among organochlorine exposures,inflammatory factors,and lung function.Results Bis(2-chloro-1-methylethyl)ether(BCIE),was negatively associated with forced vital capacity(FVC,–2.05%,95%CI:–3.11%to–0.97%),and associated with changes in inflammatory factors such as interleukin(IL)-2,IL-7,IL-8,and IL-13 in the low thyroid hormone group.The mediation analysis indicated a mediating effect of IL-2(15.63%,95%CI:0.91%to 44.64%)and IL-13(13.94%,95%CI:0.52%to 41.07%)in the association between BCIE exposure and FVC.Conclusion Lung function and inflammatory factors exhibited an increased sensitivity to organochlorine exposure at lower thyroid hormone levels,with inflammatory factors potentially mediating the adverse effects of organochlorines on lung function.
基金supported by the Natural Science Foundation of Fujian Province,China(Grant No.2023J01133509)by The Key Projects on Civil Affairs Policy and Theory Research in Fujian Province(Grant No.FMZD202402).
文摘Background:Patient participation is crucial for medication safety among older adults with chronic diseases transitioning from hospital to home,yet evidence on its levels and influencing factors remains limited.This study investigated the current state and predictors of such participation during this critical period.Methods:A cross-sectional study was conducted among older adults discharged from two tertiary hospitals in Fujian,China(October-December 2023).Data were collected using a general information questionnaire,a self-developed behavior scale,the Health Literacy Management Scale,General Self-Efficacy Scale,Facilitation of Patient Involvement Scale,and Family Support Scale.Analyses included ANOVA,Pearson correlation,and multiple stepwise regression.Results:Among 302 valid responses,the mean score for participation in medication safety behaviors was 68.59±11.62,indicating a moderate level.Health literacy,self-efficacy,healthcare worker support,and family support were positively correlated with participation(all P<0.01).Multiple regression identified daily medication frequency,health literacy,self-efficacy,and healthcare worker support as significant predictors,explaining 18.3%of the variance.Conclusion:Participation in medication safety among older chronic disease patients during care transitions requires improvement.Enhancing health literacy,self-efficacy,and healthcare worker support,while considering medication frequency,can promote patient involvement and medication safety.
文摘Hypertension,a prevalent condition among older adults,has been identified as a risk factor for cognitive decline.Nutritional status is a pivotal factor in preserving cognitive function in hypertensive older adults.Nutritional psychiatry underscores the significance of anti-inflammatory diets in promoting mental and cognitive health.This article examined the mechanisms by which body mass index,serum hemoglobin,serum albumin,and alkaline phosphatase levels predict cognitive function in hypertensive older adults.Nutrition emerges as a modifiable factor that can be targeted to maintain cognitive function in these patients.
文摘In the December 2025 issue of the Journal of Sport and Health Science,Tomkinson et al.^(1)present international norms for adult handgrip strength(HGS)developed from a systematic review of 100 studies with 2.4 million adults aged 20 to 100+years from 69 countries and regions.Twenty-eight interna-tional handGRIP Strength(iGRIPS)researchers contributed to the study.
基金supported by the Ministry of Education of Humanities and Social Science project(Grant No.22YJC890024).
文摘Background:The aging global population necessitates innovative strategies to enhance older adults’health and quality of life.Physical activity(PA)is crucial for healthy aging,yet many older adults struggle to exercise regularly.Artificial intelligence(AI)-powered social robots offer an interactive,engaging,and personalized solution to promote PA among this demographic.This systematic review investigated the role of AI-powered social robots in encouraging PA in older adults.Methods:We conducted a systematic literature search in databases including PubMed,IEEE Xplore,Scopus,Cochrane Library,and Web of Science,focusing on studies published until February 2024.We included peer-reviewed articles reporting empiricalfindings on designing,implementing,and evaluating AI-enabled social robots to promote PA among older adults.Studies were conducted in nursing homes,rehabilita-tion centers,community centers,and home environments.Results:A total of 19 studies were included in the review.Analysis reveals that AI-powered social robots effectively motivate older adults to engage in PAs,leading to increased exercise adherence,higher engagement levels,and extended training durations.Social robots have demon-strated effectiveness across various environments,including nursing homes,rehabilitation centers,community centers,home environments,and elder care facilities.In structured environments like nursing homes and rehabilitation centers,robots help maintain regular exercise routines,improving adherence and recovery outcomes.In community and elder care centers,robots promote PA and social engagement by facilitating group exercises and enhancing participation.In home environments,robots provide personalized support for daily activities,offering reminders and engagement,which fosters long-term activity engagement.User acceptance and satisfaction are high,with participantsfinding the robots engaging and enjoyable.Additionally,several studies indicate potential health benefits,such as improved medication adherence,better sleep patterns,and enhanced overall well-being.Nevertheless,additional research is imperative to address unresolved issues concerning the technolog-ical maintenance costs,design constraints,and adaptability of AI-powered social robots to specific user demographics.Conclusion:AI-powered social robots play a promising role in promoting PA among older adults,enhancing their health,well-being,and inde-pendence.This review provides insights for researchers,designers,and healthcare professionals developing AI-enabled social robotic systems for older adults.
文摘Objective: To explore the association between cardiometabolic multimorbidity and frailty among middle- aged and older adults in China. Methods: Data were derived from the 2013 wave of the China Longitudinal Healthy Longevity Survey, including a total of 6,179 individuals aged 45 years and above with complete follow-up records. Basic demographic information was collected, and frailty status was assessed using a physical frailty scale. Generalized linear models were employed to analyze the association between the number and combinations of cardiometabolic conditions- such as hypertension, diabetes, heart disease, and stroke-and frailty. Results: The prevalence of cardiometabolic multimorbidity among middle-aged and older adults was 14.23%. After adjusting for sociodemographic covariates, individuals with cardiometabolic multimorbidity had a significantly increased risk of frailty compared to those without such conditions (OR = 1.78, 95% CI: 1.45-2.19), along with higher frailty scale scores (β = 0.26, 95% CI: 0.19-0.34). Compared to individuals without cardiometabolic diseases, those with both hypertension and stroke (OR = 1.18, 95% CI: 1.06-1.31) and those with hypertension, heart disease, and stroke (OR = 1.46, 95% CI: 1.24-1.73) exhibited notably higher frailty risks. Conclusion: There is a significant association between cardiometabolic multimorbidity and frailty in middle- aged and older adults in China, particularly for comorbidity patterns involving hypertension. These findings provide evidence for developing targeted health interventions for aging populations.
