As a typical in-memory computing hardware design, nonvolatile ternary content-addressable memories(TCAMs) enable the logic operation and data storage for high throughout in parallel big data processing. However,TCAM c...As a typical in-memory computing hardware design, nonvolatile ternary content-addressable memories(TCAMs) enable the logic operation and data storage for high throughout in parallel big data processing. However,TCAM cells based on conventional silicon-based devices suffer from structural complexity and large footprintlimitations. Here, we demonstrate an ultrafast nonvolatile TCAM cell based on the MoTe2/hBN/multilayergraphene (MLG) van der Waals heterostructure using a top-gated partial floating-gate field-effect transistor(PFGFET) architecture. Based on its ambipolar transport properties, the carrier type in the source/drain andcentral channel regions of the MoTe2 channel can be efficiently tuned by the control gate and top gate, respectively,enabling the reconfigurable operation of the device in either memory or FET mode. When working inthe memory mode, it achieves an ultrafast 60 ns programming/erase speed with a current on-off ratio of ∼105,excellent retention capability, and robust endurance. When serving as a reconfigurable transistor, unipolar p-typeand n-type FETs are obtained by adopting ultrafast 60 ns control-gate voltage pulses with different polarities.The monolithic integration of memory and logic within a single device enables the content-addressable memory(CAM) functionality. Finally, by integrating two PFGFETs in parallel, a TCAM cell with a high current ratioof ∼10^(5) between the match and mismatch states is achieved without requiring additional peripheral circuitry.These results provide a promising route for the design of high-performance TCAM devices for future in-memorycomputing applications.展开更多
This paper proposes a content addres sable storage optimization method, VDeskCAS, for desktop virtualization storage based disaster backup storage system. The method implements a blocklevel storage optimization, by em...This paper proposes a content addres sable storage optimization method, VDeskCAS, for desktop virtualization storage based disaster backup storage system. The method implements a blocklevel storage optimization, by employing the algorithms of chunking image file into blocks, the blockffmger calculation and the block dedup li cation. A File system in Use Space （FUSE） based storage process for VDeskCAS is also introduced which optimizes current direct storage to suit our content addressable storage. An interface level modification makes our system easy to extend. Experiments on virtual desktop image files and normal files verify the effectiveness of our method and above 60% storage volume decrease is a chieved for Red Hat Enterprise Linux image files. Key words： disaster backup; desktop virtualization; storage optimization; content addressable storage展开更多
Titanium dioxide (TiO2) thin film was deposited on the surface of the light addressable potentiometric sensor (LAPS) to modify the sensor surface for the non-labeled detection of DNA molecules. To evaluate the effect ...Titanium dioxide (TiO2) thin film was deposited on the surface of the light addressable potentiometric sensor (LAPS) to modify the sensor surface for the non-labeled detection of DNA molecules. To evaluate the effect of ultraviolet (UV) treatment on the silanization level of TiO2 thin film by 3-aminopropyltriethoxysilane (APTS),fluorescein isothiocyanate (FITC) was used to label the amine group on the end of APTS immobilized onto the TiO2 thin film. We found that,with UV irradiation,the silanization level of the irradiated area of the TiO2 film was improved compared with the non-irradiated area under well-controlled conditions. This result indicates that TiO2 can act as a coating material on the biosensor surface to improve the effect and efficiency of the covalent immobilization of biomolecules on the sensor surface. The artificially synthesized probe DNA molecules were covalently linked onto the surface of TiO2 film. The hybridization of probe DNA and target DNA was monitored by the recording of I-V curves that shift along the voltage axis during the process of reaction. A significant LAPS signal can be detected at 10 μmol/L of target DNA sample.展开更多
This paper presents a novel biosensor for bitter substance detection on the basis of light addressable potentiometric sensor(LAPS).Taste receptor cells(TRCs)were used as sensitive elements,which can respond to differe...This paper presents a novel biosensor for bitter substance detection on the basis of light addressable potentiometric sensor(LAPS).Taste receptor cells(TRCs)were used as sensitive elements,which can respond to different bitter stimuli with extreme high sensitivity and speci-ficity.TRCs were isolated from the taste buds of rats and cultured on the surface of LAPS chip.Due to the unique advantages such as single-cell recording,light addressable capability,and noninvasiveness,LAPS chip was used as secondary transducer to monitor the responses of TRCs by recording extracelluar potential changes.The results indicate LAPS chip can effectively record the responses of TRCs to different bitter substances used in this study in a real-time manner for a long-term.In addition,by performing principal component analysis on the LAPS recording data,different bitter substances tested can be successfully discriminated.It is suggested this TRCsLAPS hybrid biosensor could be a valuable tool for bitter substance detection.With further improvement and novel design,it has great potentials to be applied in both basic research and practical applications related to bitter taste detection.展开更多
Modern shared-memory multi-core processors typically have shared Level 2(L2)or Level 3(L3)caches.Cache bottlenecks and replacement strategies are the main problems of such architectures,where multiple cores try to acc...Modern shared-memory multi-core processors typically have shared Level 2(L2)or Level 3(L3)caches.Cache bottlenecks and replacement strategies are the main problems of such architectures,where multiple cores try to access the shared cache simultaneously.The main problem in improving memory performance is the shared cache architecture and cache replacement.This paper documents the implementation of a Dual-Port Content Addressable Memory(DPCAM)and a modified Near-Far Access Replacement Algorithm(NFRA),which was previously proposed as a shared L2 cache layer in a multi-core processor.Standard Performance Evaluation Corporation(SPEC)Central Processing Unit(CPU)2006 benchmark workloads are used to evaluate the benefit of the shared L2 cache layer.Results show improved performance of the multicore processor’s DPCAM and NFRA algorithms,corresponding to a higher number of concurrent accesses to shared memory.The new architecture significantly increases system throughput and records performance improvements of up to 8.7%on various types of SPEC 2006 benchmarks.The miss rate is also improved by about 13%,with some exceptions in the sphinx3 and bzip2 benchmarks.These results could open a new window for solving the long-standing problems with shared cache in multi-core processors.展开更多
Multicore systems oftentimes use multiple levels of cache to bridge the gap between processor and memory speed.This paper presents a new design of a dedicated pipeline cache memory for multicore processors called dual...Multicore systems oftentimes use multiple levels of cache to bridge the gap between processor and memory speed.This paper presents a new design of a dedicated pipeline cache memory for multicore processors called dual port content addressable memory(DPCAM).In addition,it proposes a new replacement algorithm based on hardware which is called a near-far access replacement algorithm(NFRA)to reduce the cost overhead of the cache controller and improve the cache access latency.The experimental results indicated that the latency for write and read operations are significantly less in comparison with a set-associative cache memory.Moreover,it was shown that a latency of a read operation is nearly constant regardless of the size of DPCAM.However,an estimation of the power dissipation showed that DPCAM consumes about 7%greater than a set-associative cache memory of the same size.These results encourage for embedding DPCAM within the multicore processors as a small shared cache memory.展开更多
The article mainly studies the application strategy of automatic addressable single-lamp control technology in tunnel lighting.It encompasses an introduction to this technology,an analysis of the tunnel lighting syste...The article mainly studies the application strategy of automatic addressable single-lamp control technology in tunnel lighting.It encompasses an introduction to this technology,an analysis of the tunnel lighting system using automatic addressable single-lamp control technology,and outlines the main development direction for this technology in modern tunnel lighting.The aim is to offer insights that can inform the rational deployment of this technology,thereby enhancing the lighting control effectiveness in modern tunnels and meeting their specific lighting requirements more effectively.展开更多
Content Addressable Memory (CAM) is a type of memory used for high-speed search applications. Due to parallel comparison feature, the CAM memory leads to large power consumption which is caused by frequent pre-charge ...Content Addressable Memory (CAM) is a type of memory used for high-speed search applications. Due to parallel comparison feature, the CAM memory leads to large power consumption which is caused by frequent pre-charge or discharge of match line. In this paper, CAM for automatic charge balancing with self-control mechanism is proposed to control the voltage swing of ML for reducing the power consumption of CAM. Another technique to reduce the power dissipation is to use MSML, it combines the master-slave architecture with charge minimization technique. Unlike the conventional design, only one match line (ML) is used, whereas in Master-Slave Match Line (MSML) one master ML and several slave MLs are used to reduce the power dissipation in CAM caused by match lines (MLs). Theoretically, the match line (ML) reduces the power consumption up to 50% which is independent of search and match case. The simulation results using Cadence tool of MSML show the reduced power consumption in CAM and modified CAM cell.展开更多
We first study the impacts of soft errors on various types of CAM for different feature sizes.After presenting a soft error immune CAM cell,SSB-RCAM,we propose two kinds of reliable CAM,DCF-RCAM and DCK-RCAM. In addit...We first study the impacts of soft errors on various types of CAM for different feature sizes.After presenting a soft error immune CAM cell,SSB-RCAM,we propose two kinds of reliable CAM,DCF-RCAM and DCK-RCAM. In addition,we present an ignore mechanism to protect dual cell redundancy CAMs against soft errors.Experimental results indicate that the 11T-NOR CAM cell has an advantage in soft error immunity.Based on 11T-NOR,the proposed reliable CAMs reduce the SER by about 81%on average with acceptable overheads.The SER of dual cell redundancy CAMs can also be decreased using the ignore mechanism in specific applications.展开更多
For many biomedical and catalytic applications, such as encapsulation of proteins/enzymes in nanopartides （NPs）, it is preferable to have well-dispersed small NPs that are stable in solution and behave quasi-homogen...For many biomedical and catalytic applications, such as encapsulation of proteins/enzymes in nanopartides （NPs）, it is preferable to have well-dispersed small NPs that are stable in solution and behave quasi-homogeneously. However, conventional liquid phase methods for small-NP synthesis and functionalization usually face great difficulties in separation/purification and recycling. In addition, controlling the orientation of proteins inside NPs is also a crucial issue to maximize the activity of the encapsulated proteins. Herein, we report a solid phase method to solve these problems. Using His-tagged proteins as cores, well-dispersed core-sheU silica NPs are facilely synthesized and functionalized in a column. The core His-tagged proteins are kept bound on the surface of the resIn beads in the column during the entire process, making the separation/purification of NPs and their precursors during the multiple-step process as simple as a few-minutes procedure of draining and washing the column. Each obtained silica NP has an adjustable eccentric core-shell structure with only one His-tag sticking out of the particle. This single His-tag on the surface of each NP not only makes it easy for addressable and stoichiometric functionalization of the NP but also provides an easy way to reversibly assemble NPs into dimers or be oriented on the surface of large particles. Notably, this solid phase approach also provides a versatile means to control the orientation of proteins inside NPs, and the His-tag makes it easy to recycle those well-dispersed small NPs.展开更多
Content addressable memory （CAM） is widely used and its tests mostly use functional fault models. However, functional fault models cannot describe some physical faults exactly. This paper introduces physical fault m...Content addressable memory （CAM） is widely used and its tests mostly use functional fault models. However, functional fault models cannot describe some physical faults exactly. This paper introduces physical fault models for write-only CAM. Two test algorithms which can cover 100% targeted physical faults are also proposed. The algorithm for a CAM module with N-bit match output signal needs only 2N＋2L＋4 comparison operations and 5N writing operations, where N is the number of words and L is the word length. The algorithm for a HIT-signal-only CAM module uses 2N＋2L＋5 comparison operations and 8N writing operations. Compared to previous work, the proposed algorithms can test more physical faults with a few more operations. An experiment on a test chip shows the effectiveness and efficiency of the proposed physical fault models and algorithms.展开更多
The year 2025 marks both the 25th anniversary of the Forum on China-Africa Cooperation(FOCAC)and the first year of implementation of the outcomes of the 2024 FOCAC Beijing Summit.Throughout the year,China has supporte...The year 2025 marks both the 25th anniversary of the Forum on China-Africa Cooperation(FOCAC)and the first year of implementation of the outcomes of the 2024 FOCAC Beijing Summit.Throughout the year,China has supported Africa in addressing historical injustices at diplomatic and political levels and firmly backed South Africa in hosting the G20 Leaders’Summit,further deepening China-Africa strategic mutual trust.展开更多
在分析现有P2P(peer to peer)路由算法的基础上,提出了一种基于二阶矩定位、支持多维资源数据描述的高效资源路由算法——FAN(flabellate addressable network)路由算法.FAN算法将节点映射到统一的多维笛卡尔空间,并以节点相对空间原点...在分析现有P2P(peer to peer)路由算法的基础上,提出了一种基于二阶矩定位、支持多维资源数据描述的高效资源路由算法——FAN(flabellate addressable network)路由算法.FAN算法将节点映射到统一的多维笛卡尔空间,并以节点相对空间原点的二阶矩作为子空间管理和资源搜索的依据.FAN路由算法具有O(log(N/k))的高路由效率,在节点加入和退出FAN网络时,更新路由信息的代价为O(klog(N/k)).实验结果表明,FAN路由算法具有路由效率高、维护代价小的优点,是一种P2P环境中支持多维资源数据描述的高效结构化资源路由算法.而且,目前部分基于CAN(content-addressable network)网络的改进算法也可以在FAN网络中适用,并获得更好的路由效率和更低的维护代价.展开更多
This study explores the variations in address forms within the Tinghu dialect of Yancheng city.The findings reveal that the ways individuals address one another in this region deviate from the established principles o...This study explores the variations in address forms within the Tinghu dialect of Yancheng city.The findings reveal that the ways individuals address one another in this region deviate from the established principles of tone sandhi theory.In Chinese phonology,it is generally assumed that individual characters serve as fundamental forms based on their standard pronunciations,with real-time pronunciations adapting to phonetic conditions.However,the study of address forms has not traditionally been integrated into this framework.Observations indicate that a wide range of addressing methods is employed in social interactions,reflecting the complexity of regional cultural traits and social dynamics.This research highlights the distinctive features of address forms in the Tinghu dialect,particularly in terms of tone sandhi,vocative expressions,and indirect address.By examining these unique characteristics,the study enhances our understanding of the principles governing tonal changes in Chinese.Furthermore,it offers valuable insights into the preservation and inheritance of regional dialects.展开更多
Archroma,a global leader in specialty chemicals fo-cused on sustainable solutions,has supported the Institute of ChemicalTechnology(ICT),Mumbai,lndia in the renova-tion and development of a sustainable laboratory faci...Archroma,a global leader in specialty chemicals fo-cused on sustainable solutions,has supported the Institute of ChemicalTechnology(ICT),Mumbai,lndia in the renova-tion and development of a sustainable laboratory facility as part of its Corporate Social Responsibility(CSR)program.The upgraded facility will strengthen the department's capacity to conduct fundamental research and develop future-oriented technologies in textile processing,manufac-turing,and effluent treatment.It is designed to help address current industrial challenges while encouraging innovation in sustainable and resource-efficient textile technologies.展开更多
The blue economy encompasses all economic activities related to oceans,seas,and coastal resources,emphasizing sustainable development that balances ecological health with economic growth.It includes sectors such as fi...The blue economy encompasses all economic activities related to oceans,seas,and coastal resources,emphasizing sustainable development that balances ecological health with economic growth.It includes sectors such as fisheries,maritime trade,coastal tourism,renewable energy,and marine biotechnology.For China and ASEAN,the blue economy represents not only a source of substantial economic potential but also a crucial domain for addressing shared challenges such as resource sustainability,ecological conservation,and climate resilience.展开更多
The increasing reliance on interconnected Internet of Things(IoT)devices has amplified the demand for robust anonymization strategies to protect device identities and ensure secure communication.However,traditional an...The increasing reliance on interconnected Internet of Things(IoT)devices has amplified the demand for robust anonymization strategies to protect device identities and ensure secure communication.However,traditional anonymization methods for IoT networks often rely on static identity models,making them vulnerable to inference attacks through long-term observation.Moreover,these methods tend to sacrifice data availability to protect privacy,limiting their practicality in real-world applications.To overcome these limitations,we propose a dynamic device identity anonymization framework using Moving Target Defense(MTD)principles implemented via Software-Defined Networking(SDN).In our model,the SDN controller periodically reconfigures the network addresses and routes of IoT devices using a constraint-aware backtracking algorithmthat constructs new virtual topologies under connectivity and performance constraints.This address-hopping scheme introduces continuous unpredictability at the network layer dynamically changing device identifiers,routing paths,and even network topology which thwarts attacker reconnaissance while preserving normal communication.Experimental results demonstrate that our approach significantly reduces device identity exposure and scan success rates for attackers compared to static networks.Moreover,the dynamic schememaintains high data availability and network performance.Under attack conditions it reduced average communication delay by approximately 60% vs.an unprotected network,with minimal overhead on system resources.展开更多
BACKGROUND Heart failure with preserved ejection fraction(HFpEF)following acute myocardial infarction(AMI)carries substantial morbidity and mortality,yet reliable prognostic markers beyond conventional cardiovascular ...BACKGROUND Heart failure with preserved ejection fraction(HFpEF)following acute myocardial infarction(AMI)carries substantial morbidity and mortality,yet reliable prognostic markers beyond conventional cardiovascular factors remain limited.Frailty,reflecting diminished physiological reserve,has emerged as a potential determinant of adverse outcomes in this high-risk population.Therefore,the aim of this study was to address a critical knowledge gap and to provide evidence that may guide frailty-adapted management strategies to improve prognosis and quality of life in this high-risk population.METHODS We conducted a multicenter retrospective cohort study including 4507 patients with HFpEF discharged after AMI across 82 hospitals in China(from January 2010 to March 2024).Frailty was assessed using the Hospital Frailty Risk Score(HFRS),with HFRS<5 defined as non-frail and HFRS≥5 as frail.Multivariable Cox proportional hazards models,adjusted for demographics,comorbidities,left ventricular ejection fraction,and therapies,were applied to evaluate associations between frailty and clinical outcomes.The primary endpoints were all-cause death and major adverse cardiovascular events(MACE),which defined as the composite of cardiovascular death and heart failure rehospitalization.Secondary endpoints included net adverse clinical events(NACE),which defined as the composite of all-cause death,stroke,recurrent myocardial infarction,revascularization,and major bleeding,as well as the individual components of MACE.RESULTS Frailty was independently associated with a higher risk of all-cause death[adjusted hazard ratio(aHR)=1.52,95%CI:1.31–2.03,P=0.005]and NACE(aHR=1.20,95%CI:1.02–1.41,P=0.026).At one year,frail patients had higher unadjusted rates of all-cause death(9.0%vs.2.9%)and NACE(19.8%vs.13.7%)compared with non-frail patients.For cardiovascular death,the association did not reach statistical significance(aHR=1.42,95%CI:0.99–2.03,P=0.053).No significant associations were found for MACE(aHR=1.05,95%CI:0.86–1.28,P=0.636)or heart failure rehospitalization(aHR=0.94,95%CI:0.75–1.19,P=0.616).CONCLUSIONS Frailty,as measured by the HFRS,is an independent predictor of one-year mortality and composite adverse events in post-AMI HFpEF patients.These findings support the use of HFRS at discharge to identify high-risk population who may benefit from closer follow-up,optimization of medical therapy,and targeted frailty-focused interventions.展开更多
1 The 2025 FIRST Robotics Competition(FRC)Shanghai Regional has returned to the city,inspiring youth in science and technology.The three⁃day event,starting from March 14,has brought together nearly 1,000 young competi...1 The 2025 FIRST Robotics Competition(FRC)Shanghai Regional has returned to the city,inspiring youth in science and technology.The three⁃day event,starting from March 14,has brought together nearly 1,000 young competitors from 43 teams—including three international teams.Held at East China Normal University,the event centered on this year's theme“Reefscape”,challenging participants to address environmental issues through robotics.Teams have to design and program robots to transplant artificial coral and collect simulated algae(模拟藻类),simulating marine ecosystems'restoration processes.展开更多
基金supported by the National Key Research&Development Projects of China(Grant No.2022YFA1204100)National Natural Science Foundation of China(Grant No.62488201)+1 种基金CAS Project for Young Scientists in Basic Research(YSBR-003)the Innovation Program of Quantum Science and Technology(2021ZD0302700)。
文摘As a typical in-memory computing hardware design, nonvolatile ternary content-addressable memories(TCAMs) enable the logic operation and data storage for high throughout in parallel big data processing. However,TCAM cells based on conventional silicon-based devices suffer from structural complexity and large footprintlimitations. Here, we demonstrate an ultrafast nonvolatile TCAM cell based on the MoTe2/hBN/multilayergraphene (MLG) van der Waals heterostructure using a top-gated partial floating-gate field-effect transistor(PFGFET) architecture. Based on its ambipolar transport properties, the carrier type in the source/drain andcentral channel regions of the MoTe2 channel can be efficiently tuned by the control gate and top gate, respectively,enabling the reconfigurable operation of the device in either memory or FET mode. When working inthe memory mode, it achieves an ultrafast 60 ns programming/erase speed with a current on-off ratio of ∼105,excellent retention capability, and robust endurance. When serving as a reconfigurable transistor, unipolar p-typeand n-type FETs are obtained by adopting ultrafast 60 ns control-gate voltage pulses with different polarities.The monolithic integration of memory and logic within a single device enables the content-addressable memory(CAM) functionality. Finally, by integrating two PFGFETs in parallel, a TCAM cell with a high current ratioof ∼10^(5) between the match and mismatch states is achieved without requiring additional peripheral circuitry.These results provide a promising route for the design of high-performance TCAM devices for future in-memorycomputing applications.
基金the Hi-tech Research and Development Program of China，the National Natural Science Foundation of China，the Beijing Natural Science Foundation，the Fundamental Research Funds for the Central Universities，the Fund of the State Key Laboratory of Software Development Environment
文摘This paper proposes a content addres sable storage optimization method, VDeskCAS, for desktop virtualization storage based disaster backup storage system. The method implements a blocklevel storage optimization, by employing the algorithms of chunking image file into blocks, the blockffmger calculation and the block dedup li cation. A File system in Use Space （FUSE） based storage process for VDeskCAS is also introduced which optimizes current direct storage to suit our content addressable storage. An interface level modification makes our system easy to extend. Experiments on virtual desktop image files and normal files verify the effectiveness of our method and above 60% storage volume decrease is a chieved for Red Hat Enterprise Linux image files. Key words： disaster backup; desktop virtualization; storage optimization; content addressable storage
基金Project supported by the National Natural Science Foundation of China (Nos. 30627002 and 60725102)the Interdisciplinary Research Foundation of Zhejiang University (No. 2009-15), China
文摘Titanium dioxide (TiO2) thin film was deposited on the surface of the light addressable potentiometric sensor (LAPS) to modify the sensor surface for the non-labeled detection of DNA molecules. To evaluate the effect of ultraviolet (UV) treatment on the silanization level of TiO2 thin film by 3-aminopropyltriethoxysilane (APTS),fluorescein isothiocyanate (FITC) was used to label the amine group on the end of APTS immobilized onto the TiO2 thin film. We found that,with UV irradiation,the silanization level of the irradiated area of the TiO2 film was improved compared with the non-irradiated area under well-controlled conditions. This result indicates that TiO2 can act as a coating material on the biosensor surface to improve the effect and efficiency of the covalent immobilization of biomolecules on the sensor surface. The artificially synthesized probe DNA molecules were covalently linked onto the surface of TiO2 film. The hybridization of probe DNA and target DNA was monitored by the recording of I-V curves that shift along the voltage axis during the process of reaction. A significant LAPS signal can be detected at 10 μmol/L of target DNA sample.
基金This work was supported by the grants from the National Natural Science Foundation of China(Grant Nos.60725102,31000448)the China Postdoctoral Science Foundation(Grant Nos.20100471737,201104734)the Key Project of Zhejiang Province(Grant No.2010C14006).
文摘This paper presents a novel biosensor for bitter substance detection on the basis of light addressable potentiometric sensor(LAPS).Taste receptor cells(TRCs)were used as sensitive elements,which can respond to different bitter stimuli with extreme high sensitivity and speci-ficity.TRCs were isolated from the taste buds of rats and cultured on the surface of LAPS chip.Due to the unique advantages such as single-cell recording,light addressable capability,and noninvasiveness,LAPS chip was used as secondary transducer to monitor the responses of TRCs by recording extracelluar potential changes.The results indicate LAPS chip can effectively record the responses of TRCs to different bitter substances used in this study in a real-time manner for a long-term.In addition,by performing principal component analysis on the LAPS recording data,different bitter substances tested can be successfully discriminated.It is suggested this TRCsLAPS hybrid biosensor could be a valuable tool for bitter substance detection.With further improvement and novel design,it has great potentials to be applied in both basic research and practical applications related to bitter taste detection.
文摘Modern shared-memory multi-core processors typically have shared Level 2(L2)or Level 3(L3)caches.Cache bottlenecks and replacement strategies are the main problems of such architectures,where multiple cores try to access the shared cache simultaneously.The main problem in improving memory performance is the shared cache architecture and cache replacement.This paper documents the implementation of a Dual-Port Content Addressable Memory(DPCAM)and a modified Near-Far Access Replacement Algorithm(NFRA),which was previously proposed as a shared L2 cache layer in a multi-core processor.Standard Performance Evaluation Corporation(SPEC)Central Processing Unit(CPU)2006 benchmark workloads are used to evaluate the benefit of the shared L2 cache layer.Results show improved performance of the multicore processor’s DPCAM and NFRA algorithms,corresponding to a higher number of concurrent accesses to shared memory.The new architecture significantly increases system throughput and records performance improvements of up to 8.7%on various types of SPEC 2006 benchmarks.The miss rate is also improved by about 13%,with some exceptions in the sphinx3 and bzip2 benchmarks.These results could open a new window for solving the long-standing problems with shared cache in multi-core processors.
文摘Multicore systems oftentimes use multiple levels of cache to bridge the gap between processor and memory speed.This paper presents a new design of a dedicated pipeline cache memory for multicore processors called dual port content addressable memory(DPCAM).In addition,it proposes a new replacement algorithm based on hardware which is called a near-far access replacement algorithm(NFRA)to reduce the cost overhead of the cache controller and improve the cache access latency.The experimental results indicated that the latency for write and read operations are significantly less in comparison with a set-associative cache memory.Moreover,it was shown that a latency of a read operation is nearly constant regardless of the size of DPCAM.However,an estimation of the power dissipation showed that DPCAM consumes about 7%greater than a set-associative cache memory of the same size.These results encourage for embedding DPCAM within the multicore processors as a small shared cache memory.
文摘The article mainly studies the application strategy of automatic addressable single-lamp control technology in tunnel lighting.It encompasses an introduction to this technology,an analysis of the tunnel lighting system using automatic addressable single-lamp control technology,and outlines the main development direction for this technology in modern tunnel lighting.The aim is to offer insights that can inform the rational deployment of this technology,thereby enhancing the lighting control effectiveness in modern tunnels and meeting their specific lighting requirements more effectively.
文摘Content Addressable Memory (CAM) is a type of memory used for high-speed search applications. Due to parallel comparison feature, the CAM memory leads to large power consumption which is caused by frequent pre-charge or discharge of match line. In this paper, CAM for automatic charge balancing with self-control mechanism is proposed to control the voltage swing of ML for reducing the power consumption of CAM. Another technique to reduce the power dissipation is to use MSML, it combines the master-slave architecture with charge minimization technique. Unlike the conventional design, only one match line (ML) is used, whereas in Master-Slave Match Line (MSML) one master ML and several slave MLs are used to reduce the power dissipation in CAM caused by match lines (MLs). Theoretically, the match line (ML) reduces the power consumption up to 50% which is independent of search and match case. The simulation results using Cadence tool of MSML show the reduced power consumption in CAM and modified CAM cell.
基金supported by the National Natural Science Foundation of China(No.60703074)the National High-Tech Research and Development Program of China(No.2009AA01Z124)
文摘We first study the impacts of soft errors on various types of CAM for different feature sizes.After presenting a soft error immune CAM cell,SSB-RCAM,we propose two kinds of reliable CAM,DCF-RCAM and DCK-RCAM. In addition,we present an ignore mechanism to protect dual cell redundancy CAMs against soft errors.Experimental results indicate that the 11T-NOR CAM cell has an advantage in soft error immunity.Based on 11T-NOR,the proposed reliable CAMs reduce the SER by about 81%on average with acceptable overheads.The SER of dual cell redundancy CAMs can also be decreased using the ignore mechanism in specific applications.
基金This work was supported by the National Natural Science Foundation of China （NSFC） （Nos. 21371117 and 31571024） and the National Basic Research Program of China （No. 2016YFA0201602）.
文摘For many biomedical and catalytic applications, such as encapsulation of proteins/enzymes in nanopartides （NPs）, it is preferable to have well-dispersed small NPs that are stable in solution and behave quasi-homogeneously. However, conventional liquid phase methods for small-NP synthesis and functionalization usually face great difficulties in separation/purification and recycling. In addition, controlling the orientation of proteins inside NPs is also a crucial issue to maximize the activity of the encapsulated proteins. Herein, we report a solid phase method to solve these problems. Using His-tagged proteins as cores, well-dispersed core-sheU silica NPs are facilely synthesized and functionalized in a column. The core His-tagged proteins are kept bound on the surface of the resIn beads in the column during the entire process, making the separation/purification of NPs and their precursors during the multiple-step process as simple as a few-minutes procedure of draining and washing the column. Each obtained silica NP has an adjustable eccentric core-shell structure with only one His-tag sticking out of the particle. This single His-tag on the surface of each NP not only makes it easy for addressable and stoichiometric functionalization of the NP but also provides an easy way to reversibly assemble NPs into dimers or be oriented on the surface of large particles. Notably, this solid phase approach also provides a versatile means to control the orientation of proteins inside NPs, and the His-tag makes it easy to recycle those well-dispersed small NPs.
基金supported by the National Natural Science Foundation of China (No.60603049)the National High Technology Research and Development Program of China (Nos.2008AA110901,2007AA01Z112,2009AA01Z125)+1 种基金the State Key Development Program for Basic Research of China (No.2005CB321600)the Beijing Natural Science Foundation (No.4072024)
文摘Content addressable memory （CAM） is widely used and its tests mostly use functional fault models. However, functional fault models cannot describe some physical faults exactly. This paper introduces physical fault models for write-only CAM. Two test algorithms which can cover 100% targeted physical faults are also proposed. The algorithm for a CAM module with N-bit match output signal needs only 2N＋2L＋4 comparison operations and 5N writing operations, where N is the number of words and L is the word length. The algorithm for a HIT-signal-only CAM module uses 2N＋2L＋5 comparison operations and 8N writing operations. Compared to previous work, the proposed algorithms can test more physical faults with a few more operations. An experiment on a test chip shows the effectiveness and efficiency of the proposed physical fault models and algorithms.
文摘The year 2025 marks both the 25th anniversary of the Forum on China-Africa Cooperation(FOCAC)and the first year of implementation of the outcomes of the 2024 FOCAC Beijing Summit.Throughout the year,China has supported Africa in addressing historical injustices at diplomatic and political levels and firmly backed South Africa in hosting the G20 Leaders’Summit,further deepening China-Africa strategic mutual trust.
文摘This study explores the variations in address forms within the Tinghu dialect of Yancheng city.The findings reveal that the ways individuals address one another in this region deviate from the established principles of tone sandhi theory.In Chinese phonology,it is generally assumed that individual characters serve as fundamental forms based on their standard pronunciations,with real-time pronunciations adapting to phonetic conditions.However,the study of address forms has not traditionally been integrated into this framework.Observations indicate that a wide range of addressing methods is employed in social interactions,reflecting the complexity of regional cultural traits and social dynamics.This research highlights the distinctive features of address forms in the Tinghu dialect,particularly in terms of tone sandhi,vocative expressions,and indirect address.By examining these unique characteristics,the study enhances our understanding of the principles governing tonal changes in Chinese.Furthermore,it offers valuable insights into the preservation and inheritance of regional dialects.
文摘Archroma,a global leader in specialty chemicals fo-cused on sustainable solutions,has supported the Institute of ChemicalTechnology(ICT),Mumbai,lndia in the renova-tion and development of a sustainable laboratory facility as part of its Corporate Social Responsibility(CSR)program.The upgraded facility will strengthen the department's capacity to conduct fundamental research and develop future-oriented technologies in textile processing,manufac-turing,and effluent treatment.It is designed to help address current industrial challenges while encouraging innovation in sustainable and resource-efficient textile technologies.
文摘The blue economy encompasses all economic activities related to oceans,seas,and coastal resources,emphasizing sustainable development that balances ecological health with economic growth.It includes sectors such as fisheries,maritime trade,coastal tourism,renewable energy,and marine biotechnology.For China and ASEAN,the blue economy represents not only a source of substantial economic potential but also a crucial domain for addressing shared challenges such as resource sustainability,ecological conservation,and climate resilience.
基金supported by the National Key Research and Development Program of China(Project No.2022YFB3104300).
文摘The increasing reliance on interconnected Internet of Things(IoT)devices has amplified the demand for robust anonymization strategies to protect device identities and ensure secure communication.However,traditional anonymization methods for IoT networks often rely on static identity models,making them vulnerable to inference attacks through long-term observation.Moreover,these methods tend to sacrifice data availability to protect privacy,limiting their practicality in real-world applications.To overcome these limitations,we propose a dynamic device identity anonymization framework using Moving Target Defense(MTD)principles implemented via Software-Defined Networking(SDN).In our model,the SDN controller periodically reconfigures the network addresses and routes of IoT devices using a constraint-aware backtracking algorithmthat constructs new virtual topologies under connectivity and performance constraints.This address-hopping scheme introduces continuous unpredictability at the network layer dynamically changing device identifiers,routing paths,and even network topology which thwarts attacker reconnaissance while preserving normal communication.Experimental results demonstrate that our approach significantly reduces device identity exposure and scan success rates for attackers compared to static networks.Moreover,the dynamic schememaintains high data availability and network performance.Under attack conditions it reduced average communication delay by approximately 60% vs.an unprotected network,with minimal overhead on system resources.
基金supported by the Tianjin Key Medical Discipline(Specialty)Construction Project(TJYXZDXK-029A)the Key Project of Tianjin Natural Science Foundation(21JCZDJC01080)the Tianjin Fourth Central Hospital Outstanding Young Talent Fund(tjdszxyy20230008).
文摘BACKGROUND Heart failure with preserved ejection fraction(HFpEF)following acute myocardial infarction(AMI)carries substantial morbidity and mortality,yet reliable prognostic markers beyond conventional cardiovascular factors remain limited.Frailty,reflecting diminished physiological reserve,has emerged as a potential determinant of adverse outcomes in this high-risk population.Therefore,the aim of this study was to address a critical knowledge gap and to provide evidence that may guide frailty-adapted management strategies to improve prognosis and quality of life in this high-risk population.METHODS We conducted a multicenter retrospective cohort study including 4507 patients with HFpEF discharged after AMI across 82 hospitals in China(from January 2010 to March 2024).Frailty was assessed using the Hospital Frailty Risk Score(HFRS),with HFRS<5 defined as non-frail and HFRS≥5 as frail.Multivariable Cox proportional hazards models,adjusted for demographics,comorbidities,left ventricular ejection fraction,and therapies,were applied to evaluate associations between frailty and clinical outcomes.The primary endpoints were all-cause death and major adverse cardiovascular events(MACE),which defined as the composite of cardiovascular death and heart failure rehospitalization.Secondary endpoints included net adverse clinical events(NACE),which defined as the composite of all-cause death,stroke,recurrent myocardial infarction,revascularization,and major bleeding,as well as the individual components of MACE.RESULTS Frailty was independently associated with a higher risk of all-cause death[adjusted hazard ratio(aHR)=1.52,95%CI:1.31–2.03,P=0.005]and NACE(aHR=1.20,95%CI:1.02–1.41,P=0.026).At one year,frail patients had higher unadjusted rates of all-cause death(9.0%vs.2.9%)and NACE(19.8%vs.13.7%)compared with non-frail patients.For cardiovascular death,the association did not reach statistical significance(aHR=1.42,95%CI:0.99–2.03,P=0.053).No significant associations were found for MACE(aHR=1.05,95%CI:0.86–1.28,P=0.636)or heart failure rehospitalization(aHR=0.94,95%CI:0.75–1.19,P=0.616).CONCLUSIONS Frailty,as measured by the HFRS,is an independent predictor of one-year mortality and composite adverse events in post-AMI HFpEF patients.These findings support the use of HFRS at discharge to identify high-risk population who may benefit from closer follow-up,optimization of medical therapy,and targeted frailty-focused interventions.
文摘1 The 2025 FIRST Robotics Competition(FRC)Shanghai Regional has returned to the city,inspiring youth in science and technology.The three⁃day event,starting from March 14,has brought together nearly 1,000 young competitors from 43 teams—including three international teams.Held at East China Normal University,the event centered on this year's theme“Reefscape”,challenging participants to address environmental issues through robotics.Teams have to design and program robots to transplant artificial coral and collect simulated algae(模拟藻类),simulating marine ecosystems'restoration processes.
