A highly enantioselective intramolecular Michael addition-Lactonization domino reaction of a range of enon acids catalyzed by nuleophilic organocatalyst(Fc-PIP)was developed,furnishing cis-2,3-dihydrobenzofuran deriva...A highly enantioselective intramolecular Michael addition-Lactonization domino reaction of a range of enon acids catalyzed by nuleophilic organocatalyst(Fc-PIP)was developed,furnishing cis-2,3-dihydrobenzofuran derivatives with excellent enantioselecitivities(94%-98%ee)and good diastereoselectivities(up to 99/1).展开更多
基金The authors are grateful to the Fundamental Research Funds for the Central Universities,the National Natural Science Foundation of China(No.21372074).
文摘A highly enantioselective intramolecular Michael addition-Lactonization domino reaction of a range of enon acids catalyzed by nuleophilic organocatalyst(Fc-PIP)was developed,furnishing cis-2,3-dihydrobenzofuran derivatives with excellent enantioselecitivities(94%-98%ee)and good diastereoselectivities(up to 99/1).
