The adaptively compressed exchange(ACE)operator is a low-rank representation of the Fock exchange,avoiding any loss of precision.We present an application of this method in the formalism of linearized augmented plane ...The adaptively compressed exchange(ACE)operator is a low-rank representation of the Fock exchange,avoiding any loss of precision.We present an application of this method in the formalism of linearized augmented plane waves(LAPW)to hybrid functionals with range separation.For this purpose,we extend the functionality of the LAPW-specific Poisson solver employing the pseudocharge method for the short-and long-range interaction kernels.To make these calculations more affordable,we revise the most expensive steps in the pseudocharge method and reduce their computational complexity.As a result,this implementation is a first step towards cubic-scaling hybrid calculations employing LAPW with respect to the number of atoms.We apply our code for assessing the numerical quality of band gaps computed with hybrid functionals in the literature,employing a test set consisting of 26 materials.展开更多
Nucleus pulposus(NP)tissue engineering brings new hope in the repair of intervertebral disc degeneration(IVDD).IVDD is often accompanied by multiscale changes in the mechanical microenvironment,including the changes o...Nucleus pulposus(NP)tissue engineering brings new hope in the repair of intervertebral disc degeneration(IVDD).IVDD is often accompanied by multiscale changes in the mechanical microenvironment,including the changes of mechanical property of collagen fibril,NP tissue,and mechanical instability of spine.In this study,a multiscale mechanically-adapted strategy is proposed to promote NP repair.To achieve this goal,a viscoelasticadapted dual-network hydrogel(PVA-DN)is constructed.The hydrogel with multiscale tunable viscoelasticity and dynamic compression condition is used to meet the multiscale mechanical requirements of NP regeneration.The results show that the viscoelastic hydrogel promotes the proliferation,migration and adhesion of nucleus pulposus cell(NPC)as well as the secretion of NP-specific extracellular matrix.RNA-seq results show that it attenuates the inflammatory microenvironment by inhibiting the IL-17 signaling pathway.Appropriate dynamic compression applied to the viscoelastic scaffold further promotes the physiological function of NPC,and the viscoelasticity of hydrogel protects against NPC damage induced by excessive compression.Animal experiments demonstrate that the viscoelastic hydrogel effectively restores disc mechanical function and delays disc degen-eration in rats.Findings from this study highlight that the multiscale mechanically-adapted strategy is effective in the repair of IVDD.展开更多
Efficient and precise localization is a prerequisite for the intelligent navigation of mobile robots. Traditional visual localization systems, such as visual odometry (VO) and simultaneous localization and mapping (SL...Efficient and precise localization is a prerequisite for the intelligent navigation of mobile robots. Traditional visual localization systems, such as visual odometry (VO) and simultaneous localization and mapping (SLAM), suffer from two shortcomings: a drift problem caused by accumulated localization error, and erroneous motion estimation due to illumination variation and moving objects. In this paper, we propose an enhanced VO by introducing a panoramic camera into the traditional stereo-only VO system. Benefiting from the 360° field of view, the panoramic camera is responsible for three tasks: (1) detect- ing road junctions and building a landmark library online; (2) correcting the robot's position when the landmarks are revisited with any orientation; (3) working as a panoramic compass when the stereo VO cannot provide reliable positioning results. To use the large-sized panoramic images efficiently, the concept of compressed sensing is introduced into the solution and an adap- tive compressive feature is presented. Combined with our previous two-stage local binocular bundle adjustment (TLBBA) stereo VO, the new system can obtain reliable positioning results in quasi-real time. Experimental results of challenging long-range tests show that our enhanced VO is much more accurate and robust than the traditional VO, thanks to the compressive panoramic landmarks built online.展开更多
基金supported by the European Union's Horizon 2020 research and innovation program under the grant agreement No.951786(NOMAD CoE)the Latvian Quantum Initiative within European Union Recovery and Resilience Facility project No.2.3.1.1.i.0/1/22/I/CFLA/001.We also acknowledge the EuroHPC Joint Undertaking for awarding access to the EuroHPC supercomputer LUMI,hosted by CSC(Finland)and the LUMI consortium through a EuroHPC Development Access call.
文摘The adaptively compressed exchange(ACE)operator is a low-rank representation of the Fock exchange,avoiding any loss of precision.We present an application of this method in the formalism of linearized augmented plane waves(LAPW)to hybrid functionals with range separation.For this purpose,we extend the functionality of the LAPW-specific Poisson solver employing the pseudocharge method for the short-and long-range interaction kernels.To make these calculations more affordable,we revise the most expensive steps in the pseudocharge method and reduce their computational complexity.As a result,this implementation is a first step towards cubic-scaling hybrid calculations employing LAPW with respect to the number of atoms.We apply our code for assessing the numerical quality of band gaps computed with hybrid functionals in the literature,employing a test set consisting of 26 materials.
基金supported by the National Natural Science Foundation of China(32201070,32171350,32471410,32171321,81925027,32130059)Jiangsu Basic Research Program(Natural Science Founda-tion)(BK20240019,BK20240020)+3 种基金International Cooperation Project of Ningbo City(2023H013)Medical and Health Science and Technology Innovation Project of Suzhou(SKY2022105)Basic cutting-edge innovation cross project of Suzhou Medical College of Soochow University(YXY2302010)the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD).
文摘Nucleus pulposus(NP)tissue engineering brings new hope in the repair of intervertebral disc degeneration(IVDD).IVDD is often accompanied by multiscale changes in the mechanical microenvironment,including the changes of mechanical property of collagen fibril,NP tissue,and mechanical instability of spine.In this study,a multiscale mechanically-adapted strategy is proposed to promote NP repair.To achieve this goal,a viscoelasticadapted dual-network hydrogel(PVA-DN)is constructed.The hydrogel with multiscale tunable viscoelasticity and dynamic compression condition is used to meet the multiscale mechanical requirements of NP regeneration.The results show that the viscoelastic hydrogel promotes the proliferation,migration and adhesion of nucleus pulposus cell(NPC)as well as the secretion of NP-specific extracellular matrix.RNA-seq results show that it attenuates the inflammatory microenvironment by inhibiting the IL-17 signaling pathway.Appropriate dynamic compression applied to the viscoelastic scaffold further promotes the physiological function of NPC,and the viscoelasticity of hydrogel protects against NPC damage induced by excessive compression.Animal experiments demonstrate that the viscoelastic hydrogel effectively restores disc mechanical function and delays disc degen-eration in rats.Findings from this study highlight that the multiscale mechanically-adapted strategy is effective in the repair of IVDD.
基金Project supported by the National Natural Science Foundation of China (Nos. 61071219 and 90820306) and the Fundamental Research Funds for the Central Universities, China
文摘Efficient and precise localization is a prerequisite for the intelligent navigation of mobile robots. Traditional visual localization systems, such as visual odometry (VO) and simultaneous localization and mapping (SLAM), suffer from two shortcomings: a drift problem caused by accumulated localization error, and erroneous motion estimation due to illumination variation and moving objects. In this paper, we propose an enhanced VO by introducing a panoramic camera into the traditional stereo-only VO system. Benefiting from the 360° field of view, the panoramic camera is responsible for three tasks: (1) detect- ing road junctions and building a landmark library online; (2) correcting the robot's position when the landmarks are revisited with any orientation; (3) working as a panoramic compass when the stereo VO cannot provide reliable positioning results. To use the large-sized panoramic images efficiently, the concept of compressed sensing is introduced into the solution and an adap- tive compressive feature is presented. Combined with our previous two-stage local binocular bundle adjustment (TLBBA) stereo VO, the new system can obtain reliable positioning results in quasi-real time. Experimental results of challenging long-range tests show that our enhanced VO is much more accurate and robust than the traditional VO, thanks to the compressive panoramic landmarks built online.
